@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1738: (2016-03-28 )
MKKGLLITVMLMVMLALGACSSSESKEDQWSRIKKDKEVVIGLDDSFVPMGFRDKDDNLVGFDIDLAKAVFAEYGIKAKFTPIDWTMKESELKNGSIDLIWNGYTVTDARKKQVAFSQPYMKNEQVLVTLKSSNINQFSDMKNKTLGAQNGASSIDDMAKKPEVLTDIINNNEPELYDTFDTAFIDLNNKRIDGLIIDEVYARYYIDKQKNKDDYNIITGGFDATDFAVGMRKSDKELQKKINEAFEKLYKEGKMQEISKKWFGDDEIAKQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70....---....80--........90........100...-....110.......120.......130.-----------------------....-..140........150.--......160.......170....--...180.......190.......200.......210.-....---..---220-.-....---.-----..----230.......240.......250.......260.......270
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKK
G
L
L
I
T
V
M
L
M
V
M
L
A
LGACSSSESK
E
D
Q
W
S
R
IKKDK
E
V
V
I
GLDDSFVPMGFRDKDD
N
L
V
G
F
D
I
D
L
A
K
A
V
F
A
EYG---I
K
A
KFT--PI
D
W
T
M
K
E
S
ELKNG
S
I
D
L
I
WNG
Y
T
-VTDARKKQVAFSQPYMKN
E
Q
V
L
V
T
L
KSS-----------------------NI
N
Q
-
F
S
D
M-KNKTLGAQNGA
S
--
S
I
D
D
M
AKK
P
E
V
L
T
D
I
INNNEP
E
L
--
Y
DTF
D
T
A
F
I
DLNNKRI
D
G
L
I
I
D
E
V
Y
A
R
Y
Y
IDKQKNKD-D
Y
N
I
---
I
T---G-G-F-D
A
T
D
---
F
-----
A
V----GMRKS
D
K
E
L
Q
K
K
I
N
E
A
F
E
K
L
Y
KEG
K
M
Q
E
I
S
K
K
WFG
D
D
E
IAKQ
15
PsiBlast_PDB
82.34
26%
-53
- C2 -
3VVF
3
?
A:
[20-256]
--------------------
G
G
S
E
F
Q
V
R
S
F
E
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
G
---
L
K
P
R
W
I
--
A
Q
S
F
D
T
L
L
I
Q
L
N
Q
G
R
F
D
F
V
I
A
S
H
G
-
I
T
E
E
R
A
R
A
V
D
F
T
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
G
G
-----------------------
P
-
R
T
-
A
K
D
L
-
Q
G
K
V
V
G
V
Q
V
G
T
T
--
Y
M
E
A
A
Q
K
I
P
G
I
-------
K
E
V
R
T
--
Y
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
E
A
I
K
E
R
K
L
E
N
-
T
L
Q
V
---
G
E
---
L
-
V
-
F
-
Q
E
R
----
V
-----
A
M
----
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
-----
8
PsiBlast_PDB
81.53
28%
-74
- C2 -
2Y7I
7
?
A:
[6-227]
------------------------------------
R
T
L
H
F
G
T
S
A
T
Y
A
P
Y
E
F
V
D
A
D
N
K
I
V
G
F
D
I
D
V
A
N
A
V
C
K
E
M
Q
---
A
E
C
S
F
T
--
N
Q
S
F
D
S
L
I
P
S
L
R
F
K
K
F
D
A
V
I
A
G
M
D
-
M
T
P
K
R
E
Q
Q
V
S
F
S
Q
P
Y
Y
E
G
L
S
A
V
V
V
T
R
K
G
-----------------------
A
Y
H
T
-
F
A
D
L
-
K
G
K
K
V
G
L
E
N
G
T
T
--
H
Q
R
Y
L
Q
D
K
Q
Q
A
I
T
-------
P
V
A
--
Y
D
S
Y
L
N
A
F
T
D
L
K
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
K
W
L
---
K
N
N
P
-
D
Y
A
I
---
M
D
---
E
-
R
-
A
-
S
D
P
D
---
Y
YGK
G
L
G
I
----
A
V
R
K
D
N
D
A
L
L
Q
E
I
N
A
A
L
D
K
V
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
F
--------
13
PsiBlast_PDB
80.24
26%
-52
- C2 -
3VVD
1
?
A:
[20-256]
--------------------
G
G
S
E
F
Q
V
R
S
F
E
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
G
---
L
K
P
R
W
I
--
A
Q
S
F
D
T
L
L
I
Q
L
N
Q
G
R
F
D
F
V
I
A
S
H
G
-
I
T
E
E
R
A
R
A
V
D
F
T
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
G
G
-----------------------
P
-
R
T
-
A
K
D
L
-
Q
G
K
V
V
G
V
Q
V
G
T
T
--
Y
M
E
A
A
Q
K
I
P
G
I
-------
K
E
V
R
T
--
Y
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
E
A
I
K
E
R
K
L
E
N
-
T
L
Q
V
---
G
E
---
L
-
V
-
F
-
Q
E
R
----
V
-----
A
M
----
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
-----
18
PsiBlast_PDB
80.21
26%
-64
- C2 -
4POW
6
NOCT_AGRFC
A:
[5-257]
------------------------------------
K
S
I
T
I
A
T
E
G
S
Y
A
P
Y
N
F
K
D
A
G
G
K
L
I
G
F
D
I
D
L
G
N
D
L
C
K
R
M
N
---
I
E
C
K
F
V
--
E
Q
A
W
D
G
I
I
P
S
L
T
A
G
R
Y
D
A
I
M
A
A
M
G
-
I
Q
P
A
R
E
K
V
I
A
F
S
R
P
Y
L
L
T
P
M
T
F
L
T
T
A
D
S
PLLKTQVAIENLPLDNIT
P
E
Q
K
A
E
L
D
K
-
F
T
K
I
F
E
G
V
K
F
G
V
Q
A
G
T
S
---------
H
E
A
F
M
K
Q
M
M
P
S
V
Q
I
S
T
--
Y
D
T
I
D
N
V
V
M
D
L
K
A
G
R
I
D
A
S
L
A
S
V
S
F
L
K
P
L
T
D
K
P
D
N
K
D
-
L
K
M
F
G
P
R
M
T
---
G
-
G
-
L
-
F
G
K
G
---
V
-----
G
V
----
G
I
R
K
E
D
A
D
L
K
A
L
F
D
K
A
I
D
A
A
I
A
D
G
T
V
Q
K
L
S
Q
Q
W
F
G
Y
D
A
S
P
--
53
HHSearch
79.61
27%
-61
- C2 -
1XT8
1
?
A:
[34-265]
--------------------------
L
N
S
L
D
K
I
K
Q
N
G
V
V
R
I
G
V
F
G
D
K
P
P
F
G
Y
V
D
E
K
G
N
N
Q
G
Y
D
I
A
L
A
K
R
I
A
K
E
L
F
GDE
N
K
V
Q
F
V
--
L
V
E
A
A
N
R
V
E
F
L
K
S
N
K
V
D
I
I
L
A
N
F
T
-
Q
T
P
Q
R
A
E
Q
V
D
F
C
S
P
Y
M
K
V
A
L
G
V
A
V
P
K
D
S
-----------------------
N
I
T
S
-
V
E
D
L
-
K
D
K
T
L
L
L
N
K
G
T
T
--
A
D
A
Y
F
T
Q
N
Y
-------
P
N
I
K
T
L
K
--
Y
D
Q
N
T
E
T
F
A
A
L
M
D
K
R
G
D
A
L
S
H
D
N
T
L
L
F
A
W
V
K
D
H
--
P
--
D
F
K
M
---
G
I
---
K
-
E
-
L
G
N
K
D
V
---
I
-----
A
P
----
A
V
K
K
G
D
K
E
L
K
E
F
I
D
N
L
I
I
K
L
G
Q
E
Q
F
F
H
K
A
Y
D
E
T
L
K
-------
45
HHSearch
79.26
28%
-62
- C2 -
2Y7I
7
?
A:
[3-228]
---------------------------------
V
S
A
R
T
L
H
F
G
T
S
A
T
Y
A
P
Y
E
F
V
D
A
D
N
K
I
V
G
F
D
I
D
V
A
N
A
V
C
K
E
M
Q
---
A
E
C
S
F
T
--
N
Q
S
F
D
S
L
I
P
S
L
R
F
K
K
F
D
A
V
I
A
G
M
D
-
M
T
P
K
R
E
Q
Q
V
S
F
S
Q
P
Y
Y
E
G
L
S
A
V
V
V
T
R
K
G
-----------------------
A
Y
H
T
-
F
A
D
L
-
K
G
K
K
V
G
L
E
N
G
T
T
--
H
Q
R
Y
L
Q
D
K
Q
-------
Q
A
I
T
P
V
A
--
Y
D
S
Y
L
N
A
F
T
D
L
K
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
K
W
L
K
N
N
--
P
--
D
Y
A
I
---
M
D
E
R
A
S
D
P
D
Y
-
Y
G
K
G
---
L
-----
G
I
----
A
V
R
K
D
N
D
A
L
L
Q
E
I
N
A
A
L
D
K
V
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
F
T
-------
19
PsiBlast_PDB
79.13
26%
-66
- C2 -
4POX
9
NOCT_AGRFC
A:
[5-257]
------------------------------------
K
S
I
T
I
A
T
E
G
S
Y
A
P
Y
N
F
K
D
A
G
G
K
L
I
G
F
D
I
D
L
G
N
D
L
C
K
R
M
N
---
I
E
C
K
F
V
--
E
Q
A
W
D
G
I
I
P
S
L
T
A
G
R
Y
D
A
I
M
A
A
M
G
-
I
Q
P
A
R
E
K
V
I
A
F
S
R
P
Y
L
L
T
P
M
T
F
L
T
T
A
D
S
PLLKTQVAIE
N
L
P
L
DNIT
P
E
Q
K
A
E
L
D
K
-
F
T
K
I
F
E
G
V
K
F
G
V
Q
A
G
T
S
---------
H
E
A
F
M
K
Q
M
M
P
S
V
Q
I
S
T
--
Y
D
T
I
D
N
V
V
M
D
L
K
A
G
R
I
D
A
S
L
A
S
V
S
F
L
K
P
L
T
D
K
P
D
N
K
D
-
L
K
M
F
G
P
R
M
T
---
G
-
G
-
L
-
F
G
K
G
---
V
-----
G
V
----
G
I
R
K
E
D
A
D
L
K
A
L
F
D
K
A
I
D
A
A
I
A
D
G
T
V
Q
K
L
S
Q
Q
W
F
G
Y
D
A
S
P
--
20
PsiBlast_PDB
78.77
29%
-83
- C2 -
1HSL
6
HISJ_ECOLI
A:
[4-231]
------------------------------------
Q
K
I
R
I
G
T
D
P
T
Y
A
P
F
E
S
K
N
A
Q
G
E
L
V
G
F
D
I
D
L
A
K
E
L
C
K
R
I
N
---
T
Q
C
T
F
V
E
N
P
L
D
A
L
I
--
P
S
L
K
A
K
K
I
D
A
I
M
S
S
L
S
-
I
T
E
K
R
Q
Q
E
I
A
F
T
D
K
L
Y
A
A
D
S
R
L
V
V
A
K
N
S
-----------------------
D
I
Q
P
T
V
A
S
L
-
K
G
K
R
V
G
V
L
Q
G
T
T
Q
E
T
F
G
N
E
H
W
A
P
K
G
I
-
E
I
V
S
--------
Y
Q
G
Q
D
N
I
Y
S
D
L
T
A
G
R
I
D
A
A
F
Q
D
E
V
A
A
S
E
G
F
L
K
Q
P
V
G
K
-
D
Y
K
F
--------
G
-
G
-
P
-
A
V
K
D
EKL
F
-----
G
V
G
T
G
M
G
L
R
K
E
D
N
E
L
R
E
A
L
N
K
A
F
A
E
M
R
A
D
G
T
Y
E
K
L
A
K
K
Y
F
--------
16
PsiBlast_PDB
78.73
26%
-63
- C2 -
4PP0
10
NOCT_AGRFC
A:
[5-257]
------------------------------------
K
S
I
T
I
A
T
E
G
S
Y
A
P
Y
N
F
K
D
A
G
G
K
L
I
G
F
D
I
D
L
G
N
D
L
C
K
R
M
N
---
I
E
C
K
F
V
--
E
Q
A
W
D
G
I
I
P
S
L
T
A
G
R
Y
D
A
I
M
A
A
M
G
-
I
Q
P
A
R
E
K
V
I
A
F
S
R
P
Y
L
L
T
P
N
T
F
L
T
T
A
D
S
PLLKTQVAIENLPLDNIT
P
E
Q
K
A
E
L
D
K
-
F
T
K
I
F
E
G
V
K
F
G
V
Q
A
G
T
S
---------
H
E
A
F
M
K
Q
M
M
P
S
V
Q
I
S
T
--
Y
D
T
I
D
N
V
V
M
D
L
K
A
G
R
I
D
A
S
L
A
S
V
S
F
L
K
P
L
T
D
K
P
D
N
K
D
-
L
K
M
F
G
P
R
M
T
---
G
-
G
-
L
-
F
G
K
G
---
V
-----
G
V
----
G
I
R
K
E
D
A
D
L
K
A
L
F
D
K
A
I
D
A
A
I
A
D
G
T
V
Q
K
L
S
Q
Q
W
F
G
Y
D
A
S
P
--
12
PsiBlast_PDB
78.46
26%
-55
- C2 -
3VV5
1
?
A:
[24-256]
------------------------
F
Q
V
R
S
F
E
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
G
---
L
K
P
R
W
I
--
A
Q
S
F
D
T
L
L
I
Q
L
N
Q
G
R
F
D
F
V
I
A
S
H
G
-
I
T
E
E
R
A
R
A
V
D
F
T
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
G
G
-----------------------
P
-
R
T
-
A
K
D
L
-
Q
G
K
V
V
G
V
Q
V
G
T
T
--
Y
M
E
A
A
Q
K
I
P
G
I
-------
K
E
V
R
T
--
Y
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
E
A
I
K
E
R
K
L
E
N
-
T
L
Q
V
---
G
E
---
L
-
V
-
F
-
Q
E
R
----
V
-----
A
M
----
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
-----
14
PsiBlast_PDB
78.30
26%
-53
- C2 -
3VVE
2
?
A:
[20-256]
--------------------
G
G
S
E
F
Q
V
R
S
F
E
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
G
---
L
K
P
R
W
I
--
A
Q
S
F
D
T
L
L
I
Q
L
N
Q
G
R
F
D
F
V
I
A
S
H
G
-
I
T
E
E
R
A
R
A
V
D
F
T
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
G
G
-----------------------
P
-
R
T
-
A
K
D
L
-
Q
G
K
V
V
G
V
Q
V
G
T
T
--
Y
M
E
A
A
Q
K
I
P
G
I
-------
K
E
V
R
T
--
Y
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
E
A
I
K
E
R
K
L
E
N
-
T
L
Q
V
---
G
E
---
L
-
V
-
F
-
Q
E
R
----
V
-----
A
M
----
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
-----
49
HHSearch
78.08
28%
-75
- C2 -
2PVU
3
?
A:
[38-265]
--------------------------------
G
A
T
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
-
K
G
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
A
T
T
--
G
Q
E
A
A
E
K
L
F
G
------
K
G
P
H
I
K
K
--
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
--
P
N
K
K
L
Q
V
---
I
E
D
--
P
-
K
N
F
-
A
S
E
Y
---
Y
-----
G
M
----
I
F
P
K
-
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
----
22
PsiBlast_CBE
78.03
31%
-77
- C2 -
2Q2C
3
?
C:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----
55
HHSearch
77.04
23%
-62
- C2 -
2YLN
10
?
A:
[48-280]
---------------------------
S
L
I
E
R
I
N
N
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
T
Y
H
D
K
D
G
K
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
G
---
V
K
V
E
F
K
--
E
T
Q
W
D
S
M
M
A
G
L
K
A
G
R
F
D
V
V
A
N
Q
V
G
L
T
S
P
E
R
Q
A
T
F
D
K
S
E
P
Y
S
W
S
G
A
V
L
V
A
H
N
D
S
-----------------------
N
I
K
S
-
I
A
D
I
-
K
G
V
K
T
A
Q
S
L
T
S
N
--
Y
G
E
K
A
K
A
---------
A
G
A
Q
L
V
P
--
V
D
G
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
D
Y
L
K
K
N
--
P
N
A
G
V
K
I
---
V
W
---
S
A
P
A
D
-
E
K
V
G
---
S
-----
G
L
----
I
V
N
K
G
N
D
E
A
V
A
K
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
----
23
PsiBlast_CBE
77.04
31%
-78
- C2 -
2Q2C
3
?
B:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----
24
PsiBlast_CBE
76.97
31%
-74
- C2 -
2Q2A
2
?
D:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----
26
PsiBlast_CBE
76.72
31%
-75
- C2 -
2Q2A
2
?
B:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----
17
PsiBlast_PDB
76.64
26%
-61
- C2 -
4P0I
4
NOCT_AGRFC
A:
[5-259]
------------------------------------
K
S
I
T
I
A
T
E
G
S
Y
A
P
Y
N
F
K
D
A
G
G
K
L
I
G
F
D
I
D
L
G
N
D
L
C
K
R
M
N
---
I
E
C
K
F
V
--
E
Q
A
W
D
G
I
I
P
S
L
T
A
G
R
Y
D
A
I
M
A
A
M
G
-
I
Q
P
A
R
E
K
V
I
A
F
S
R
P
Y
L
L
T
P
M
T
F
L
T
T
A
D
S
PLLKTQVAIENLPLDNIT
P
E
Q
K
A
E
L
D
K
-
F
T
K
I
F
E
G
V
K
F
G
V
Q
A
G
T
S
---------
H
E
A
F
M
K
Q
M
M
P
S
V
Q
I
S
T
--
Y
D
T
I
D
N
V
V
M
D
L
K
A
G
R
I
D
A
S
L
A
S
V
S
F
L
K
P
L
T
D
K
P
D
N
K
D
-
L
K
M
F
G
P
R
M
T
---
G
-
G
-
L
-
F
G
K
G
---
V
-----
G
V
----
G
I
R
K
E
D
A
D
L
K
A
L
F
D
K
A
I
D
A
A
I
A
D
G
T
V
Q
K
L
S
Q
Q
W
F
G
Y
D
A
S
P
K
Q
5
PsiBlast_PDB
76.64
31%
-76
- C2 -
2Q2C
2
?
A:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----
21
PsiBlast_CBE
76.63
31%
-76
- C2 -
2Q2C
2
?
D:
[42-264]
------------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
K
G
-
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
G
---
L
D
Y
E
L
K
--
N
I
G
W
D
P
L
F
A
S
L
Q
S
K
E
V
D
M
G
I
S
G
I
T
-
I
T
D
E
R
K
Q
S
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
S
-----------------------
P
V
K
N
-
A
L
D
L
-
K
G
K
T
I
G
V
Q
N
-
A
T
--
T
G
Q
E
A
A
E
K
-------
L
F
G
K
G
P
H
I
KK
F
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
Y
V
K
N
N
P
N
K
K
-
L
Q
V
I
---
E
D
---
P
-
K
-
N
-
F
A
S
E
---
Y
-----
Y
G
----
M
I
F
P
K
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
-----