@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1758: (2016-03-28 )
MADKKRYEELINILDQYSYDYYVIDNPTVEDAEYDQKMQELLKIEEAHPEWVTPESPSKRVGGEVLEGFKKVAHDTPMLSLANAFNHEDLADFDRRIRDKVGDDIAYMCELKIDGLAVSLQYENGKYKQGATRGDGTIGEDITANLRTIRSIPMKLQKDYSIEVRGEAFMPKRSFQKLNEIREEEGQMLFANPRNAAAGSLRQLDTKIAASRNLDIFLYAVADFGEMGVETHSAGLDMLETLGLKVNKERRLCSSLEEVYAYIDEWTEKRADLAYDIDGIVLKLNNLEQQRQMGTTVKSPRWSIAYKFPAEEVPTKLLDIELNVGRTGVITPTAVLEPVRVAGTTVSRASLHNEDLITEKDIRIGDTVLIKKAGDIIPEVIKSITEERSGSEEPFHMPKKCPTCDSELVRLEEEVALRCINPKCPAQIKEGLIHFVSRNAMNIDGLGEKVIIQLFSQHLIKDVADLFFLSKEKLLELERMGEKSVTNLLASIEASKQNSLEKLLFGLGIRHVGAKAAKSLAVHFETMDNLKVADKETLTSINDIGEKMADSIVTYFANEEVHDLLEELKRAGVNMTYTGPKLEDMSEEELVFAGKTVVLTGKLEKLTRNDAKALIESLGGNVSGSVSKKTDVVVAGSDAGSKLAKAEELAIPIWSEEDLIEYLPDEGGLNE
Atome Classification :
(33 SA)
---...-......10........20........30........40........50........60...-.-..-..70........80........90........100-.---..---.--.....110.......120.......130.......140.......150.....------.---.---160---.----.......170.......180.......190.......200.......210.......220---..-.---..-..230-.-........240......--.250-.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420..-......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MA
D
-
K
K
R
Y
E
E
L
I
N
I
L
D
QYSY
D
Y
Y
V
IDNPTVE
D
A
E
Y
D
Q
K
M
Q
E
L
L
K
I
EEAHPEWVTPESPSKRV
G
G
E
-
V
-
L
E
-
G
F
K
K
V
AHDT
P
M
L
S
L
A
N
AFN
H
E
D
L
A
D
F
D
R
R
I
R
D
K---V---GD---D--
I
A
Y
M
C
E
L
K
ID
G
L
A
V
S
L
Q
YENGKYKQGATRGDGTIG
E
D
I
T
A
N
L
R
T
I
R
S
I
P
M
K
LQ------K---D---
Y
-
S
---
I
----
E
VRGEAFM
P
K
R
S
F
Q
K
L
N
E
I
R
E
EEG
Q
M
L
F
ANPRNAAAG
S
L
R
Q
L
D
T
K
IAASRNL
D
I
F
L
Y
A
V
A
---
D
F
-
G
---EM-GV
E
---
T
-
H
S
A
G
L
D
M
L
E
T
LGLKVN
K
--
E
R
R
L
-
C
S
S
L
E
E
V
Y
A
Y
I
D
E
W
T
E
K
RAD
L
A
YDI
D
G
I
V
L
K
LN
N
L
E
Q
Q
R
QMGTTVKSP
R
W
S
I
A
Y
KF
P
A
E
EVPT
K
L
L
D
I
E
L
NVGRTGVI
T
P
T
A
VLE
P
V
R
VAG
T
T
V
S
RASLHNEDLITEKDIRIG
D
T
V
L
I
KKA
G
D
I
I
P
E
V
I
K
S
I
T
E
ERSGSEEPFHMPKKCPTC
D
S
E
L
V
R
L
E
E
E
V
A
L
R
CIN-PK-C
P
A
Q
I
K
E
G
L
I
H
F
V
SRNAMNIDGL
G
E
K
V
I
I
Q
L
F
S
Q
H
L
I
K
D
V
A
D
L
F
F
L
S
K
E
K
L
L
E
L
E
RMG
E
K
S
V
T
N
L
L
A
S
I
EA
S
K
Q
N
S
L
E
K
L
L
F
G
L
G
I
R
H
V
G
A
K
A
A
K
S
L
A
V
H
F
E
TMDNLKVA
D
K
E
T
L
T
S
I
N
D
I
G
E
K
M
A
D
S
I
V
T
Y
FA
N
E
E
V
H
D
L
L
E
E
L
K
RAGV
N
M
T
YTGPKLEDMSEE
E
L
V
FAG
K
T
V
V
L
TG
K
L
E
K
L
T
R
N
D
A
K
A
L
I
E
S
LGGNVSGSVSKK
T
D
V
V
V
AGSDAGSKLAKAEELAIPIW
S
E
E
D
L
I
E
YLPDEGGLNE
1
PsiBlast_PDB
92.15
46%
-73
- C4 -
2OWO
8
DNLJ_ECOLI
A:
[5-586]
-------
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
-
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
---
L
---
K
N
---
N
EK
V
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
------
G
---
E
NIP
A
-
R
---
L
----
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
VL-
E
G
-
G
---
E
L
-
P
-
D
---
T
-
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
--
R
V
T
L
-
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
-
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
--
W
P
A
P
-------------------------------------------------------------------------------------------
34
HHSearch
91.97
46%
-72
- C4 -
2OWO
8
DNLJ_ECOLI
A:
[2-586]
---
E
S
I
-
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
-
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
---
L
---
K
N
NE-
K
--
V
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
G
E
N---
I
---
P
---
A
-
R
---
L
----
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
---
V
L
-
E
---
G
G
E
L
P
D
---
T
-
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
--
R
V
T
L
-
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
-
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.08
45%
-76
- C4 -
4GLX
5
DNLJ_ECOLI
A:
[5-582]
-------
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
-----
P
-
L
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
----------------
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
------
G
---
E
NIP
A
-
R
---
L
----
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
VL-
E
G
-
G
---
E
L
-
P
-
D
---
T
-
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
--
R
V
T
L
-
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
-
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
-------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
87.23
45%
-68
- C4 -
1V9P
2
DNLJ_THEFI
A:
[7-581]
-------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
A
---
L
---
G
R
---
K
RP
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
V--
P
---
D
-
R
---
L
----
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L--
G
L
-
E
---
E
S
-
G
L
K
---
S
-
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
--
E
G
K
V
H
R
C
P
N
-
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.95
45%
-65
- C4 -
1V9P
2
DNLJ_THEFI
B:
[7-581]
-------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
A
---
L
---
G
R
---
K
RP
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
V--
P
---
D
-
R
---
L
----
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L--
G
L
-
E
---
E
S
-
G
L
K
---
S
-
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
GY
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
--
E
G
K
V
H
R
C
P
N
-
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
------------------------------------------------------------------------------------------------
56
Fugue
86.65
44%
-64
- C4 -
1DGS
2
DNLJ_THEFI
A:
[1-581]
MT
R
E
E
A
-
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
---
A
---
E
A
---
P
--
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
--
V
W
S
T
G
S
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
---
V
---
P
D
R
---
L
----
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
---
L
G
-
L
GLE
E
S
-
G
L
K
---
S
-
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
--
C
Y
E
K
-
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
--
V
K
E
G
K
V
H
R
C
P
N
-
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
21
PsiBlast_CBE
85.84
43%
-62
- C4 -
1DGS
2
DNLJ_THEFI
B:
[7-581]
-------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
---
A
---
E
A
---
P
--
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
V--
P
---
D
-
R
---
L
----
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
LGL
G
L
-
E
---
E
S
-
G
L
K
---
S
-
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
CY
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
--
E
G
K
V
H
R
C
P
N
-
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
-------
E
S
K
--------------------------------------------------------------------------------------
3
PsiBlast_PDB
85.04
43%
-62
- C4 -
1DGS
2
DNLJ_THEFI
A:
[7-581]
-------
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
-
P
-
L
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
---
A
---
E
A
---
P
--
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
V--
P
---
D
-
R
---
L
----
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
LGL
G
L
-
E
---
E
S
-
G
L
K
---
S
-
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
---
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
--
E
G
K
V
H
R
C
P
N
-
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
-------
E
S
K
--------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.40
58%
-56
- C4 -
4EEQ
4
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.23
58%
-59
- C4 -
3BA8
5
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
69.75
58%
-57
- C4 -
4EFE
4
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
69.54
58%
-58
- C4 -
4EFB
4
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.44
58%
-58
- C4 -
3BA9
9
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
69.12
58%
-54
- C4 -
1TA8
4
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.77
58%
-56
- C4 -
3BAA
8
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
68.26
58%
-57
- C4 -
3BAB
7
DNLJ_ENTFA
A:
[10-317]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
68.07
58%
-57
- C4 -
4LH6
5
DNLJ_ENTFA
A:
[10-323]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
67.74
58%
-50
- C4 -
1TAE
7
DNLJ_ENTFA
B:
[10-324]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
67.43
58%
-55
- C4 -
1TAE
5
DNLJ_ENTFA
C:
[10-324]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
67.08
58%
-55
- C4 -
1TAE
12
DNLJ_ENTFA
D:
[10-324]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
66.77
58%
-53
- C4 -
4CC5
2
DNLJ_STAAU
A:
[2-309]
----
A
D
L
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
-
A
-
Q
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
Q
---
I
---
G
N
------
V
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
K
------
E
---
P
---
L
-
N
---
V
----
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
S
V
N
---
D
F
-
T
---
D
F
-
N
A
R
---
S
-
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
K
--
N
R
A
R
-
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
66.45
58%
-54
- C4 -
4LH7
4
DNLJ_ENTFA
A:
[10-322]
----
A
A
-
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
-
V
-
L
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
---
I
---
G
K
---
P
--
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
------
E
---
P
---
I
-
S
---
V
----
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
---
D
F
-
G
---
P
M
-
K
A
K
---
T
-
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
--
E
R
Q
L
-
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
65.14
58%
-55
- C4 -
4CC6
2
DNLJ_STAAU
A:
[2-309]
----
A
D
L
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
-
A
-
Q
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
Q
---
I
---
G
N
------
V
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
K
------
E
---
P
---
L
-
N
---
V
----
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
S
V
N
---
D
F
-
T
---
D
F
-
N
A
R
---
S
-
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
K
--
N
R
A
R
-
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
63.54
47%
-46
- C4 -
3UQ8
2
DNLJ_HAEIN
A:
[2-321]
-----
I
-
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
R
---
L
---
I
L
LPA
P
--
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
------
T
DNP
P
---
A
-
R
---
L
----
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
---
I
A
-
E
---
G
V
D
L
P
T
---
T
-
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
--
E
I
R
L
-
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
62.13
47%
-49
- C4 -
3UQ8
2
DNLJ_HAEIN
A:
[3-318]
-------
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
R
LIL
L
---
P
A
---
P
--
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
------
T
---
D
---
N
-
P
PA
R
L
----
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
----
I
-
A
---
E
--
G
V
D
LPT
T
-
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
--
E
I
R
L
-
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
61.36
47%
-52
- C4 -
3PN1
2
DNLJ_HAEIN
A:
[5-318]
-------
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
-
P
-
L
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LIL
L
---
P
K
---
P
--
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
------
T
---
D
---
N
-
P
PA
R
L
----
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
----
I
-
A
---
E
--
G
V
D
LPT
T
-
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
--
E
I
R
L
-
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
60.83
49%
-55
- C4 -
4GLW
4
DNLJ_STRZP
B:
[3-304]
--------
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
-
V
-
L
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
E
---
V
---
A
H
---
P
---
T
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
P
------
E
---
E
---
L
-
D
---
I
----
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
Q
E
A
---
S
P
-
S
---
T
R
---
D
---
S
-
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
P
--
K
R
I
L
-
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
60.63
41%
-33
- C4 -
3SGI
1
DNLJ_MYCTU
A:
[12-415]
----
E
V
-
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
-
G
F
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
---
V
---
G
D
---
A
--
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
P
G
DDYP
V
---
P
---
E
-
V
---
L
----
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
G
L
G
---
H
V
-
E
---
G
F
-
R
P
A
---
T
-
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
E
--
H
T
T
L
-
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
E
A
Q
T
K
L
L
D
I
R
V
N
V
G
R
T
G
R
I
T
P
F
A
F
M
T
P
V
K
V
A
G
S
T
V
G
Q
A
T
L
H
N
A
S
E
I
K
R
K
G
V
L
I
G
D
T
V
V
I
R
K
A
G
D
V
I
P
E
V
L
G
P
V
V
E
L
R
D
G
S
E
R
E
F
I
M
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
60.05
41%
-34
- C4 -
3SGI
1
DNLJ_MYCTU
A:
[15-415]
--------
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
F
-
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
---
V
---
G
D
---
A
--
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
------
P
G
D-
D
---
Y
-
P
---
V
PE
V
L
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
G
L
G
---
H
V
E
G
---
F
R
-
P
A
T
---
L
-
H
Q
A
Y
L
-
A
L
R
A
W
G
L
P
V
S
E
--
H
T
T
L
-
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
E
A
Q
T
K
L
L
D
I
R
V
N
V
G
R
T
G
R
I
T
P
F
A
F
M
T
P
V
K
V
A
G
S
T
V
G
Q
A
T
L
H
N
A
S
E
I
K
R
K
G
V
L
I
G
D
T
V
V
I
R
K
A
G
D
V
I
P
E
V
L
G
P
V
V
E
L
R
D
G
S
E
R
E
F
I
M
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
59.35
49%
-52
- C4 -
4GLW
3
DNLJ_STRZP
A:
[3-305]
--------
K
R
M
N
E
-----------------------------
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
-
V
-
L
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
E
---
V
---
A
H
---
P
---
T
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
P
------
E
---
E
---
L
-
D
---
I
----
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
Q
E
A
---
S
P
-
S
---
T
R
---
D
---
S
-
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
P
--
K
R
I
L
-
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
57.29
42%
-46
- C4 -
1ZAU
1
DNLJ_MYCTU
A:
[12-328]
----
E
V
-
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
-
G
F
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
---
V
---
G
D
---
A
--
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
P
G
D
DYP
V
---
P
---
E
-
V
---
L
----
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
G
L
G
---
H
V
-
E
---
G
F
-
R
P
A
---
T
-
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
E
--
H
T
T
L
-
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
55.71
42%
-44
- C4 -
1ZAU
1
DNLJ_MYCTU
A:
[15-328]
--------
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
F
-
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
---
V
---
G
D
---
A
--
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
------
P
G
D
-
D
---
Y
-
P
---
V
PEVL
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
R
M
I
C
H
G
L
G
---
H
V
E
G
---
F
R
-
P
A
T
---
L
-
H
Q
A
Y
L
-
A
L
R
A
W
G
L
P
V
S
E
--
H
T
T
L
-
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
53.26
48%
-53
- C4 -
3BAC
4
DNLJ_HAEIN
A:
[6-260]
--------------------------------------------------------------------------
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
---
L
ILL
P
K
---
P
--
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
------
T
---
D
---
N
-
P
PA
R
L
----
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
---
I
A
-
E
---
G
V
-
G
L
P
---
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
--
E
I
R
L
-
C
N
G
A
D
E
V
L
D
F
Y
Q
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------