@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1871: (2016-03-29 )
MNQSETKALEALQNGSDIRGIAIATEKYQITLTDERVEKIAYGFAKWLKEEKKVEGQAKVAIGHDSRLSAERLKAALVKGLTFAGIDVVDVGLATTPAMFMATQYEDYDCDAGIMITASHLPFMYNGLKLFTKSGGAEHEDIDYIVAHADKSFIENGLNLGKVTKQDLLSTYAADLTDKIRAGITDAADKMKPLQGSHIIVDAGNGAGGFFAEKVLAELGADISESQFLDPDGNFPNHIPNPDNEEAMASLKKAVLASGADLGVIFDTDVDRAAIMDKNGESLNRNPLIAVISSIILEEKPGTTIVTDSTTSGHLQAFIEAKGGKQHRFKRGYRNVINEALRLNANGTPSEIAIEVSGHAALKENYFLDDGAYLIAKILMTYATLRKNGQDLPDLIADLKEPAESEEIRLSITANDFKAYGKEALADFLTFVEADPDMELEPVNQEGIRVNTKGALGEGWFLLRMSLHEPVMPMNLESDEAGGIRKVKDRLAGFFATKADLKM
Atome Classification :
(20 SA)
.........10.....-...20........30........40........50........60........70........80........90........100...------....110.......120.......130.......-140.......150......---.------160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360....-.-..370.......380.......390.......400.......410.......420.......430.......440.......450----.......460.......470.......480.......490.....---..500.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
Q
S
E
T
K
A
L
E
A
L
QNGS-D
I
R
G
I
A
I
A
T
E
K
Y
Q
I
T
L
T
D
E
R
V
E
K
I
A
Y
G
F
A
K
W
L
K
E
E
K
KVEG
Q
A
K
V
A
IGHDSRL
S
A
E
R
L
K
A
A
L
V
KG
L
T
F
AG
I
D
V
V
DVGLATTP
A
M
F
M
A
T
QY------EDYDCDA
G
I
M
I
T
ASH
L
P
F
M
YN
G
L
K
L
F
TKSGGAEH-EDID
Y
I
V
AHA
D
K
S
F
I
E
NGL---N------LG
K
V
T
K
Q
D
L
L
S
T
Y
A
A
D
L
T
D
K
I
R
AGIT
D
A
A
DKMKPLQG
S
H
I
I
V
DAGNGA
G
G
F
F
A
E
K
V
L
A
E
LGADISESQFLDPDGNFPNHIPNPD
N
E
E
A
M
A
S
L
K
K
A
V
L
ASGA
D
L
G
V
I
F
DTDVDR
A
A
I
MDKNGESLNRN
P
L
I
A
V
I
S
S
I
I
LEEKPG
T
T
I
V
TDSTTS
G
H
L
Q
A
F
I
EAKGGK
Q
H
R
F
K
R
G
Y
R
N
V
I
N
E
A
LRLNANGTP
S
E
I
A
I
E
VSG
H
A
A
LKENY-F-LDD
G
A
Y
L
I
A
K
I
L
M
T
Y
A
T
L
RKNGQ
D
L
P
D
L
I
A
D
L
KEPAES
E
E
I
R
L
S
I
T
A
N
D
F
K
A
Y
G
K
E
A
L
A
D
F
L
T
F
VEADPDMELEPVNQE
G
I
R
VNT----KGALGE
G
W
F
L
L
R
MSLHEPVMPMNLESDEAG
G
I
R
K
V
K
D
R
L
A
G
F
FAT---KADLKM
46
Fugue
94.72
28%
-67
- C1 -
1K2Y
2
ALGC_PSEAE
X:
[5-463]
---
K
A
P
T
L
P
A
S
I
F
R
A
Y
-
D
I
R
G
V
------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
----
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
A
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
-----------
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
-
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
-----
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
---
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
E
D
S
-----
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
I
T
T
L
D
--
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
VDS
S
L
P
V
P
F
22
PsiBlast_CBE
94.70
32%
-68
- C1 -
1WQA
1
?
C:
[10-427]
------------------
V
R
G
I
A
--
N
E
K
----
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
L
L
K
R
E
G
R
--
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
-
K
E
R
E
A
I
V
---
E
E
L
F
F
K
E
D
F
---
D
RAKWYE
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
K
V
D
---
V
E
A
I
K
K
R
K
P
F
----
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
-
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
-
N
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
-
D
L
I
V
A
R
A
L
Y
E
N
-
N
G
T
---
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
-
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
---
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
Y
Y
Q
I
K
T
K
R
-
H
V
E
G
D
R
H
A
I
V
N
K
V
A
----------------
E
M
A
R
E
R
G
Y
T
V
D
T
TDGA
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
----------------------------------
23
PsiBlast_CBE
94.62
32%
-69
- C1 -
1WQA
1
?
B:
[10-427]
------------------
V
R
G
I
A
--
N
E
K
----
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
L
L
K
R
E
G
R
--
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
-
K
E
R
E
A
I
V
---
E
E
L
F
F
K
E
D
F
---
D
RAKWYE
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
K
V
D
---
V
E
A
I
K
K
R
K
P
F
----
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
-
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
-
N
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
-
D
L
I
V
A
R
A
L
Y
E
N
-
N
G
T
---
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
-
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
---
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
Y
Y
Q
I
K
T
K
R
-
H
V
E
G
D
R
H
A
I
V
N
K
V
A
----------------
E
M
A
R
E
R
G
Y
T
V
D
T
TDGA
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
----------------------------------
13
PsiBlast_PDB
94.59
32%
-69
- C1 -
1WQA
1
?
A:
[10-427]
------------------
V
R
G
I
A
--
N
E
K
----
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
L
L
K
R
E
G
R
--
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
-
K
E
R
E
A
I
V
---
E
E
L
F
F
K
E
D
F
---
D
RAKWYE
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
K
V
D
---
V
E
A
I
K
K
R
K
P
F
----
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
-
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
-
N
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
-
D
L
I
V
A
R
A
L
Y
E
N
-
N
G
T
---
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
-
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
---
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
Y
Y
Q
I
K
T
K
R
-
H
V
E
G
D
R
H
A
I
V
N
K
V
A
----------------
E
M
A
R
E
R
G
Y
T
V
D
T
TD
G
A
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
----------------------------------
1
PsiBlast_PDB
94.57
28%
-59
- C1 -
4MRQ
13
ALGC_PSEAE
A:
[10-437]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
2
PsiBlast_PDB
94.53
28%
-61
- C1 -
1K2Y
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
A
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
12
PsiBlast_PDB
94.27
28%
-64
- C1 -
3C04
1
ALGC_PSEAE
A:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
G
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
11
PsiBlast_PDB
94.26
28%
-60
- C1 -
3BKQ
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
G
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
21
PsiBlast_CBE
93.80
32%
-68
- C1 -
1WQA
1
?
D:
[10-427]
------------------
V
R
G
I
A
--
N
E
K
----
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
L
L
K
R
E
G
R
--
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
-
K
E
R
E
A
I
V
---
E
E
L
F
F
K
E
D
F
---
D
RAKWYE
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
K
V
D
---
V
E
A
I
K
K
R
K
P
F
----
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
T
V
N
-
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
-
N
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
-
D
L
I
V
A
R
A
L
Y
E
N
-
N
G
T
---
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
-
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
---
K
S
G
K
K
F
S
E
L
I
D
E
L
P
K
Y
Y
Q
I
K
T
K
R
-
H
V
E
G
D
R
H
A
I
V
N
K
V
A
----------------
E
M
A
R
E
R
G
Y
T
V
D
T
TDGA
K
I
I
F
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
----------------------------------
10
PsiBlast_PDB
93.46
28%
-63
- C1 -
2H5A
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
9
PsiBlast_PDB
93.41
28%
-61
- C1 -
2H4L
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
7
PsiBlast_PDB
93.36
28%
-64
- C1 -
1PCJ
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
8
PsiBlast_PDB
93.09
28%
-62
- C1 -
1PCM
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
14
PsiBlast_PDB
93.05
28%
-61
- C1 -
4IL8
3
ALGC_PSEAE
A:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
A
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
25
HHSearch
92.99
29%
-66
- C1 -
1WQA
1
?
A:
[3-454]
-----------
K
L
F
G
T
F
G
V
R
G
I
A
------
N
E
K
I
T
P
E
F
A
M
K
I
G
M
A
F
G
T
L
L
K
R
E
G
--
R
K
K
P
L
V
V
V
G
R
D
T
R
V
S
G
E
M
L
K
E
A
L
I
S
G
L
L
S
V
G
C
D
V
I
D
V
G
I
A
P
T
P
A
V
Q
W
A
T
K
H
--------
F
N
A
D
G
G
A
V
I
T
A
S
H
N
P
P
E
Y
N
G
I
K
L
L
E
P
N
G
M
G
L
K
-
K
E
R
E
A
I
V
E
E
L
F
F
K
E
D
F
D
R
A
KWY
E
------
I
G
E
V
R
R
E
D
I
I
K
P
Y
I
E
A
I
K
S
K
V
D
V
E
A
------
I
K
K
-
R
K
P
F
V
V
V
D
T
S
N
G
A
G
S
L
T
L
P
Y
L
L
R
E
L
G
C
K
V
I
-
T
V
N
A
Q
P
D
G
Y
F
P
A
R
N
P
E
P
N
-
E
E
N
L
K
E
F
M
E
I
V
K
A
L
G
A
D
F
G
V
A
Q
D
G
D
A
D
R
A
V
F
I
D
E
N
G
R
F
I
Q
G
D
K
T
F
A
L
V
A
D
A
V
L
K
E
K
G
G
G
L
L
V
T
T
V
A
T
S
N
L
L
D
D
I
A
K
K
H
G
A
K
V
M
R
T
K
V
G
D
L
I
V
A
R
A
L
Y
E
-----
N
N
G
T
I
G
G
E
E
N
G
G
V
I
F
P
E
H
V
-
L
-
G
R
D
G
A
M
T
V
A
K
V
V
E
I
F
A
K
S
---
G
K
K
F
S
E
L
I
D
E
L
P
K
Y
Y
Q
I
---
K
T
K
R
H
-
V
E
G
-
D
R
H
-
A
I
V
N
K
V
A
E
---
M
A
R
E
R
G
Y
T
V
D
T
T
D
G
A
K
I
I
F
--------
E
D
G
W
V
L
V
R
A
S
G
T
E
P
I
I
R
I
F
S
E
A
K
S
K
E
K
A
Q
E
Y
L
N
L
G
I
E
L
L
E
K
---
A
L
----
5
PsiBlast_PDB
92.93
28%
-63
- C1 -
1P5D
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
6
PsiBlast_PDB
92.81
28%
-60
- C1 -
1P5G
2
ALGC_PSEAE
X:
[18-445]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
29
HHSearch
92.71
28%
-70
- C1 -
3UW2
10
?
A:
[22-477]
-------
M
I
S
Q
S
I
F
K
A
Y
D
I
R
G
V
I
------
G
K
T
L
D
A
D
V
A
R
S
I
G
R
A
F
G
S
E
V
R
A
Q
----
G
G
D
A
V
V
V
A
R
D
G
R
L
S
G
P
E
L
V
G
A
L
A
D
G
L
R
A
A
G
V
D
V
V
D
V
G
M
V
P
T
P
V
G
Y
F
A
A
S
V
PLALSG
G
E
R
R
V
D
S
C
I
V
V
T
G
S
H
N
P
P
D
Y
N
G
F
K
M
V
L
R
-
G
A
A
I
Y
G
D
Q
I
Q
G
L
Y
K
R
I
V
D
A
R
F
--
E
T
---
G
------
S
G
S
Y
E
Q
Y
D
V
A
D
Q
Y
V
E
R
I
V
G
D
I
K
L
-----------
T
R
P
L
K
L
V
V
D
A
G
N
G
V
A
G
P
L
A
T
R
L
F
K
A
L
G
C
E
L
V
-
E
L
F
T
D
I
D
G
N
F
P
N
H
H
P
D
P
A
H
P
E
N
L
Q
D
V
I
A
K
L
K
A
T
D
A
E
I
G
F
A
F
D
G
D
G
D
R
L
G
V
V
T
K
D
G
Q
I
I
Y
P
D
R
Q
L
M
L
F
A
E
E
V
L
S
R
N
P
G
A
Q
I
I
Y
D
V
K
C
T
R
N
L
A
R
W
V
R
E
K
G
G
E
P
L
M
W
K
T
G
H
S
L
V
K
A
K
L
R
E
-----
T
G
A
P
L
A
G
E
M
S
G
H
V
F
F
K
D
R
W
Y
G
-
F
D
D
G
L
Y
T
G
A
R
L
L
E
I
L
A
R
V
----
A
D
P
S
A
L
L
N
G
L
P
N
A
V
S
T
P
E
--
L
Q
L
-------
N
V
K
-
L
I
D
K
L
R
A
D
A
K
-
F
D
G
-
A
D
E
V
V
T
I
D
G
L
R
V
E
Y
--------
P
D
G
F
G
L
A
R
S
S
N
T
T
P
V
V
V
L
R
F
E
A
T
S
D
A
A
L
A
R
I
Q
D
D
F
R
R
A
L
K
A
---
A
-----
4
PsiBlast_PDB
92.60
28%
-60
- C1 -
2FKM
2
ALGC_PSEAE
X:
[17-444]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
D
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------
3
PsiBlast_PDB
92.57
28%
-61
- C1 -
2FKF
2
ALGC_PSEAE
A:
[17-444]
-----------------
D
I
R
G
V
----------
V
G
D
T
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
E
S
L
A
R
G
E
P
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
--------
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
G
E
T
L
A
N
-
E
Q
I
Q
A
L
R
E
R
I
E
K
N
D
L
A
S
G
V
-----------
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
--------
K
P
M
K
---
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
-
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
R
N
P
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
-
S
L
I
K
K
K
M
K
----
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
-
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
---
E
I
L
S
Q
D
Q
R
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
T
V
T
-
E
D
S
K
F
A
I
I
E
A
L
Q
R
D
A
Q
W
G
E
G
N
------
I
T
T
L
D
G
V
R
V
D
Y
----
P
----
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
------------------