@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1877: (2016-03-29 )
MSNKVKSDIEIASKAEILPVTTIAEHLGLDADALELYGKYKAKLSYDTIHSLKDKEPGKLVLVTAINPTPAGEGKSTVTVGLGDALSKKDKKTVIALREPSLGPTMGIKGGATGGGYAQVIPMEDINLHFTGDFHAITAANNALSAFIDNHMQQGNDLEIDGRRIVWKRVVDLNDRALRKVVVGLGGPIQGVPREDGFDITVASEIMAIICLASDLKDLKKRLSEIVIGYNYKKEPITVGEMGYEGALTLLLKDALKPNLVQTLEHTPAIVHGGPFANIAHGCNSVSATSTALRLGDYVVTEAGFGADLGAEKFLDIKVPALGKAPDCVVIVATIRALKMHGGALKTELSEENVDALAKGFTNLQKHTESIQTFGIPYVVAINKFITDSDAEVAKLEALCEEHGIPFSLTEVWEKVAMAAWNSRIK
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.....---------..410.......420....----------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSNKVKSDIEIASKA
E
I
L
P
V
T
T
I
A
E
H
LGL
D
A
D
A
L
E
L
Y
G
K
Y
K
A
KLSY
D
T
I
H
S
LKDKEPG
K
L
V
L
V
T
AINPTPAGEG
K
S
T
V
T
V
GLGDALSKKDK
K
T
V
I
A
L
REPSLGPTMGIKGGATGGG
Y
A
Q
V
I
P
ME
D
I
N
L
H
F
TGD
F
H
A
I
T
AA
N
N
A
L
S
A
F
I
D
N
H
MQQGNDLEIDG
R
R
I
V
W
K
R
VVDL
N
D
R
A
L
R
K
V
V
V
GLGGPIQGVPREDGF
D
I
T
V
A
S
E
I
M
A
I
I
C
L
A
S
D
L
K
D
L
K
K
R
L
S
E
I
V
I
GYNYKKEP
I
T
VGEMGY
E
G
A
L
T
L
L
L
K
D
ALK
P
N
L
V
Q
T
L
EHTPAIVHGGP
F
A
N
I
A
H
GCNSVSA
T
S
T
A
L
R
LG
D
Y
V
VTEAGFGADLGA
E
K
F
L
D
I
KVPALGKAP
D
C
V
V
I
V
A
T
I
R
A
L
K
MHGGALKTELSE
E
N
V
D
A
L
A
K
G
F
T
N
L
Q
K
H
T
E
S
I
Q
T
FG
I
P
Y
V
V
A
I
N
K
FITDSD
A
E
V
A
K
L
E
A
L
C
E
EHGIPF---------
S
L
T
E
V
W
E
K
V
A
M
A
A
W
NSRIK----------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
93.09
64%
-93
- C5 -
4JKI
6
FTHS_MOOTH
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
92.84
64%
-89
- C5 -
4IOK
6
FTHS_MOOTA
B:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
92.39
64%
-90
- C5 -
4IOK
7
FTHS_MOOTA
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
92.29
61%
-94
- C5 -
1EG7
7
FTHS_MOOTH
A:
[7-555]
-------
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
E
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
K
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
A
LSWAKGGE
G
G
L
E
L
A
R
K
V
L
Q
T
L
E
S
R
P
S
N
FHVLYNLDLS
I
K
D
K
I
A
K
I
A
T
EIYGAD
G
V
N
Y
T
A
E
A
D
K
A
I
Q
R
Y
E
S
L
GYGN
L
P
V
V
M
AKTQYSFSDDMTKLGRPRN
F
T
I
T
V
R
E
V
R
L
SAG
G
R
L
I
V
P
I
T
GAIMT
M
P
G
L
P
KRPAACN
I
D
I
D
ADGVITG---------
21
PsiBlast_CBE
92.29
64%
-90
- C5 -
4JJK
4
FTHS_MOOTH
B:
[5-414]
-----
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
92.24
64%
-91
- C5 -
4IOL
4
FTHS_MOOTA
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
92.24
64%
-91
- C5 -
4JJK
8
FTHS_MOOTH
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
92.15
64%
-91
- C5 -
4IOJ
5
FTHS_MOOTA
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
91.87
64%
-90
- C5 -
4JJZ
6
FTHS_MOOTH
A:
[5-414]
-----
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
91.80
64%
-89
- C5 -
4IOM
7
FTHS_MOOTA
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
91.78
64%
-89
- C5 -
4IOJ
5
FTHS_MOOTA
B:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.76
64%
-93
- C5 -
4JIM
6
FTHS_MOOTH
A:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
91.54
64%
-93
- C5 -
4JKI
2
FTHS_MOOTH
B:
[5-414]
-----
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
91.48
64%
-91
- C5 -
4IOL
3
FTHS_MOOTA
B:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
91.34
64%
-92
- C5 -
4JIM
5
FTHS_MOOTH
B:
[5-414]
-----
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
90.81
64%
-89
- C5 -
4JJZ
7
FTHS_MOOTH
B:
[7-414]
-------
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
90.43
64%
-88
- C5 -
4IOM
4
FTHS_MOOTA
B:
[3-414]
---
K
V
P
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
E
V
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
90.07
63%
-89
- C5 -
1EG7
7
FTHS_MOOTH
A:
[7-412]
-------
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
E
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
K
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
--
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
89.88
63%
-87
- C5 -
3QUS
7
FTHS_MOOTH
A:
[6-412]
------
S
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
--
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------
55
Fugue
89.72
61%
-80
- C5 -
1FPM
8
FTHS_MOOTH
A:
[7-555]
-------
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
W
A
K
G
G
E
G
G
L
E
L
A
R
K
V
L
Q
T
L
E
SRPSNFHVLYNLDLS
I
K
D
K
I
A
K
I
A
T
EIYGAD
G
V
N
Y
T
A
E
A
D
K
A
I
Q
R
Y
E
S
L
GYGN
L
P
V
V
M
AKTQYSFSDDMTKLGRPRN
F
T
I
T
V
R
E
V
R
L
S
AGGR
L
I
V
P
I
T
GAIMT
M
P
G
L
P
KRPAACN
I
D
I
D
ADGVITG
27
PsiBlast_CBE
89.61
63%
-85
- C5 -
3QUS
5
FTHS_MOOTH
B:
[7-412]
-------
D
I
E
I
A
Q
A
A
K
M
K
P
V
M
E
L
A
R
G
L
G
I
Q
E
D
E
V
E
L
Y
G
K
Y
K
A
K
I
S
L
D
V
Y
R
R
L
K
D
K
P
D
G
K
L
I
L
V
T
A
I
T
P
T
P
A
G
E
G
K
T
T
T
S
V
G
L
T
D
A
L
A
R
L
G
K
R
V
M
V
C
L
R
E
P
S
L
G
P
S
F
G
I
K
G
G
A
A
G
G
G
Y
A
Q
V
V
P
M
E
D
I
N
L
H
F
T
G
D
I
H
A
V
T
Y
A
H
N
L
L
A
A
M
V
D
N
H
L
Q
Q
G
N
V
L
N
I
D
P
R
T
I
T
W
R
R
V
I
D
L
N
D
R
A
L
R
N
I
V
I
G
L
G
G
K
A
N
G
V
P
R
E
T
G
F
D
I
S
V
A
S
E
V
M
A
C
L
C
L
A
S
D
L
M
D
L
K
E
R
F
S
R
I
V
V
G
Y
T
Y
D
G
K
P
V
T
A
G
D
L
E
A
Q
G
S
M
A
L
L
M
K
D
A
I
K
P
N
L
V
Q
T
L
E
N
T
P
A
F
I
H
G
G
P
F
A
N
I
A
H
G
C
N
S
I
I
A
T
K
T
A
L
K
L
A
D
Y
V
V
T
E
A
G
F
G
A
D
L
G
A
E
K
F
Y
D
V
K
C
R
Y
A
G
F
K
P
D
A
T
V
I
V
A
T
V
R
A
L
K
M
H
G
G
V
P
K
S
D
L
A
T
E
N
L
E
A
L
R
E
G
F
A
N
L
E
K
H
I
E
N
I
G
K
F
G
V
P
A
V
V
A
I
N
A
F
P
T
D
T
E
A
E
L
N
L
L
Y
E
L
C
A
K
A
G
A
E
V
---------
A
L
S
--
W
A
K
---------------------------------------------------------------------------------------------------------------------------------------------