@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1894: (2016-03-29 )
LLSNKQTVLCIEEMAKMFPAAHCELVHKNTFELLVAVVLSAQCTDVLVNRVTASLFEKYHSPEDYLAVPLEELMEDIRSIGLYRNKAKNIQGLSEKILTEFNGEVPKTHAELESLPGVGRKTANVVLSVGFGVPAIAVDTHVERISKRLGICRWKDSVVEVEETLKRKLPKELWSDAHHYMIFFGRYHCKARNPECPTCPLLYLCREGKKQAKVRGFDG
Atome Classification :
(20 SA)
.........10........20.---...--------..---..30........40........50........60........70........80........90........100.......110..-.-....120.......130.......140......-.----150...---.------...----160----.........170..------------...------------..180.......190.......200.......210.......----------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
LLSNK
Q
T
V
L
C
I
E
E
M
A
K
M
F
P
A
A
H
---
C
E
L
--------
V
H---K
N
T
F
E
L
L
V
A
V
V
L
SAQ
C
T
D
V
L
V
N
R
V
T
A
S
L
F
E
K
YHSP
E
D
Y
L
AV
P
L
E
E
L
M
E
D
I
R
SIGLYRNKA
K
N
I
Q
G
L
S
E
K
I
L
T
E
FNGEVP
K
T
H
A
E
L
E
S-L-PGVGRK
T
A
N
V
V
L
S
VGFGV
P
A
I
A
V
D
T
H
V
E
R
I
S
K
R
-L----GICRWK---
D
------
S
V
V
----
E
------
V
E
E
T
L
K
R
KL
P
K
E
L
W
------------SDA------------H
H
Y
M
I
F
F
G
R
Y
H
C
KARNPECPT
C
P
L
L
Y
L
C
REGKKQAKVRGFDG----------------------------------------------------------------------------------------------------------------------------
24
HHSearch
97.45
71%
-126
- C2 -
1ORN
5
?
A:
[5-216]
-
L
T
K
Q
Q
I
R
Y
C
L
D
E
M
A
K
M
F
P
D
A
H
---
C
E
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
E
V
P
R
D
R
D
E
L
M
K
-
L
-
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
-
L
----
G
F
C
R
W
D
---
D
------
S
V
L
----
E
------
V
E
K
T
L
M
K
I
I
P
K
E
E
W
------------
S
I
T
------------
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
R
E
G
K
K
R
M
R
----------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
97.29
70%
-126
- C2 -
1ORN
5
?
A:
[4-217]
M
L
T
K
Q
Q
I
R
Y
C
L
D
E
M
A
K
M
F
P
D
A
H
---
C
E
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
E
V
P
R
D
R
D
E
L
M
K
-
L
-
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
-
L
----
G
F
C
R
W
D
---
D
------
S
V
L
----
E
------
V
E
K
T
L
M
K
I
I
P
K
E
E
W
------------
S
I
T
------------
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
R
E
G
K
K
R
M
R
K
---------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
96.54
70%
-125
- C2 -
1ORP
4
?
A:
[4-216]
M
L
T
K
Q
Q
I
R
Y
C
L
D
E
M
A
K
M
F
P
D
A
H
---
C
E
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
E
V
P
R
D
R
D
E
L
M
K
-
L
-
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
-
L
----
G
F
C
R
W
D
---
D
------
S
V
L
----
E
------
V
E
K
T
L
M
K
I
I
P
K
E
E
W
------------
S
I
T
------------
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
R
E
G
K
K
R
M
R
----------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
96.52
70%
-126
- C2 -
1P59
4
?
A:
[4-217]
M
L
T
K
Q
Q
I
R
Y
C
L
D
E
M
A
K
M
F
P
D
A
H
---
C
E
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
E
V
P
R
D
R
D
E
L
M
K
-
L
-
P
G
V
G
R
K
T
A
N
V
V
V
S
T
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
-
L
----
G
F
C
R
W
D
---
D
------
S
V
L
----
E
------
V
E
K
T
L
M
K
I
I
P
K
E
E
W
------------
S
I
T
------------
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
R
E
G
K
K
R
M
R
K
---------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
86.83
43%
-120
- C2 -
2ABK
1
END3_ECOLI
A:
[3-210]
---
K
A
K
R
L
E
I
L
T
R
L
R
E
N
N
P
H
P
T
---
T
E
L
--------
N
F
---
S
S
P
F
E
L
L
I
A
V
L
L
S
A
Q
A
T
D
V
S
V
N
K
A
T
A
K
L
Y
P
V
A
N
T
P
A
A
M
L
E
L
G
V
E
G
V
K
T
Y
I
K
T
I
G
L
Y
N
S
K
A
E
N
I
I
K
T
C
R
I
L
L
E
Q
H
N
G
E
V
P
E
D
R
A
A
L
E
A
-
L
-
P
G
V
G
R
K
T
A
N
V
V
L
N
T
A
F
G
W
P
T
I
A
V
D
T
H
I
F
R
V
C
N
R
-
T
----
Q
F
A
P
-
G
---
K
------
N
V
E
----
Q
------
V
E
E
K
L
L
K
V
V
P
A
E
F
K
------------
V
D
C
------------
H
H
W
L
I
L
H
G
R
Y
T
C
I
A
R
K
P
R
C
G
S
C
I
I
E
D
L
C
E
Y
K
E
K
V
D
-----------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
82.90
46%
-116
- C2 -
2ABK
1
END3_ECOLI
A:
[18-208]
------------------
P
H
P
T
---
T
E
L
--------
N
F
---
S
S
P
F
E
L
L
I
A
V
L
L
S
A
Q
A
T
D
V
S
V
N
K
A
T
A
K
L
Y
P
V
A
N
T
P
A
A
M
L
E
L
G
V
E
G
V
K
T
Y
I
K
T
I
G
L
Y
N
S
K
A
E
N
I
I
K
T
C
R
I
L
L
E
Q
H
N
G
E
V
P
E
D
R
A
A
L
E
A
-
L
-
P
G
V
G
R
K
T
A
N
V
V
L
N
T
A
F
G
W
P
T
I
A
V
D
T
H
I
F
R
V
C
N
R
-
T
----
Q
F
A
P
G
K
---
N
-------
V
E
----
Q
------
V
E
E
K
L
L
K
V
V
P
A
E
F
K
------------
V
D
C
------------
H
H
W
L
I
L
H
G
R
Y
T
C
I
A
R
K
P
R
C
G
S
C
I
I
E
D
L
C
E
Y
K
E
K
-------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
75.29
20%
-93
- C2 -
1RRQ
4
?
A:
[12-362]
-----
P
A
R
E
F
Q
R
D
L
L
D
W
F
A
R
E
R
---
R
D
L
--------
P
W
RKD
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
-
L
-
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
-
L
F
LVT
D
D
I
A
K
C
---
S
------
T
R
K
----
R
------
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
------------
G
A
F
------------
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
-
Q
A
F
A
E
G
V
A
E
E
L
P
V
KMV
K
Q
V
P
L
A
V
A
V
L
A
D
DE
G
R
V
L
I
R
K
R
D
STGLLAN
L
W
E
F
PSCETDGADG
K
E
K
L
E
Q
M
VGL
Q
V
E
L
T
E
PI
V
S
F
E
H
A
F
SHLVWQ
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
R
L
A
P
EDELKA
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
28
HHSearch
71.58
21%
-93
* C2 *
3FSP
4
?
A:
[11-223]
----
F
P
A
R
E
F
Q
R
D
L
L
D
W
F
A
R
E
R
RDL
P
W
R
--------
K
D
---
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
-
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
-
L
-
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
-
L
----
F
L
V
T
D
D
---
I
AK
P
S
--
T
R
K
----
R
------
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
------------
G
A
F
------------
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
69.68
23%
-96
- C2 -
4YOQ
5
?
A:
[37-226]
-----------------------------------------
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
-
L
-
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
-
L
----
F
L
V
--
T
---
D
------
D
I
A
----
K
CS
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
------------
G
A
F
------------
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
-----------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
69.42
23%
-101
- C2 -
3G0Q
4
?
A:
[26-215]
-----------------------------------------
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
-
L
-
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
-
L
----
F
L
V
--
T
---
D
------
D
I
A
----
K
CS
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
------------
G
A
F
------------
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
-----------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
68.87
21%
-95
- C2 -
3N5N
1
MUTYH_HUMAN
X:
[13-240]
----
A
E
V
T
A
F
R
G
S
L
L
S
W
Y
D
Q
E
K
RDL
P
W
R
RRAEDEMD
L
D
---
R
R
A
Y
A
V
W
V
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
N
Y
Y
T
G
W
M
Q
K
W
P
T
L
Q
D
L
A
S
A
S
L
E
E
V
N
Q
L
W
A
G
L
G
Y
Y
S
-
R
G
R
R
L
Q
E
G
A
R
K
V
V
E
E
L
G
G
H
M
P
R
T
A
E
T
L
Q
Q
L
L
-
P
G
V
G
R
Y
T
A
G
A
I
A
S
I
A
F
G
Q
A
T
G
V
V
D
G
N
V
A
R
V
L
C
R
-
V
----
R
A
I
G
A
D
---
P
SSTL--
V
S
Q
----
Q
------
L
W
G
L
A
Q
Q
L
V
D
P
A
R
P
------------
G
D
F
------------
N
Q
A
A
M
E
L
G
A
T
V
C
T
P
Q
R
P
L
C
S
Q
C
P
V
E
S
L
C
R
A
R
Q
R
V
E
-----------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
68.23
23%
-89
- C2 -
1KEA
8
GTMR_METTF
A:
[8-219]
-----
K
R
K
V
F
V
S
T
I
L
T
F
W
N
T
D
R
R
D
F
P
W
R
--------
H
T
---
R
D
P
Y
V
I
L
I
T
E
I
L
L
R
R
T
T
A
G
H
V
K
K
I
Y
D
K
F
F
V
K
Y
K
C
F
E
D
I
L
K
T
P
K
S
E
I
A
K
D
I
K
E
I
G
L
S
N
Q
R
A
E
Q
L
K
E
L
A
R
V
V
I
N
D
Y
G
G
R
V
P
R
N
R
K
A
I
L
D
-
L
-
P
G
V
G
K
Y
T
C
A
A
V
M
C
L
A
F
G
K
K
A
A
M
V
D
A
N
F
V
R
V
I
N
R
-
Y
----
F
G
G
S
Y
E
NLN
Y
------
N
H
K
----
A
------
L
W
E
L
A
E
T
L
V
P
G
G
K
C
------------
R
D
F
------------
N
L
G
L
M
D
F
S
A
I
I
C
A
P
R
K
P
K
C
E
K
C
G
M
S
K
L
C
S
Y
Y
E
K
C
------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
67.25
27%
-103
- C2 -
1KEA
8
GTMR_METTF
A:
[27-213]
-----------------
F
P
W
R
H
---------------
T
---
R
D
P
Y
V
I
L
I
T
E
I
L
L
R
R
T
T
A
G
H
V
K
K
I
Y
D
K
F
F
V
K
Y
K
C
F
E
D
I
L
K
T
P
K
S
E
I
A
K
D
I
K
E
I
G
L
S
N
Q
R
A
E
Q
L
K
E
L
A
R
V
V
I
N
D
Y
G
G
R
V
P
R
N
R
K
A
I
L
D
-
L
-
P
G
V
G
K
Y
T
C
A
A
V
M
C
L
A
F
G
K
K
A
A
M
V
D
A
N
F
V
R
V
I
N
R
-
Y
----
F
G
G
S
Y
E
---
N
LNYNH
K
A
L
W
----
E
------
L
A
E
T
L
---
V
P
G
G
K
C
------------
R
D
F
------------
N
L
G
L
M
D
F
S
A
I
I
C
A
P
R
K
P
K
C
E
K
C
G
M
S
K
L
C
------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
65.69
21%
-88
- C2 -
1KG2
6
MUTY_ECOLI
A:
[5-215]
-----
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
T
L--
P
W
Q
--------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
-
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
-
C
----
Y
A
V
S
G
W
---
P
------
G
K
K
E
V
E
N
K
------
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
------------
E
R
F
------------
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
-----------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.51
24%
-102
- C2 -
3N5N
1
MUTYH_HUMAN
X:
[45-238]
------------------------------------
L
D
---
R
R
A
Y
A
V
W
V
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
N
Y
Y
T
G
W
M
Q
K
W
P
T
L
Q
D
L
A
S
A
S
L
E
E
V
N
Q
L
W
A
G
L
G
Y
Y
-
S
R
G
R
R
L
Q
E
G
A
R
K
V
V
E
E
L
G
G
H
M
P
R
T
A
E
T
L
Q
Q
-
L
L
P
G
V
G
R
Y
T
A
G
A
I
A
S
I
A
F
G
Q
A
T
G
V
V
D
G
N
V
A
R
V
----------
L
C
R
V
R
---
A
------
I
G
A
----
D
------
P
S
S
T
L
---
V
S
Q
Q
L
W
GLAQQLVDPARP
G
D
F
------------
N
Q
A
A
M
E
L
G
A
T
V
C
T
P
Q
R
P
L
C
S
Q
C
P
V
E
S
L
C
R
A
R
Q
R
-------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.83
23%
-88
- C2 -
1WEF
1
MUTY_ECOLI
A:
[26-208]
------------------------------------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
-
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
----
A
V
S
G
W
P
---
G
-------------------------
K
K
E
V
E
N
K
L
W
------------
S
L
S
E
Q
V
TPAVG
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
63.79
23%
-87
- C2 -
1KG7
5
MUTY_ECOLI
A:
[26-208]
------------------------------------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
-
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
----
A
V
S
G
W
P
---
G
-------------------------
K
K
E
V
A
N
K
L
W
------------
S
L
S
E
Q
V
TPAVG
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
63.35
23%
-85
- C2 -
1KG2
6
MUTY_ECOLI
A:
[26-208]
------------------------------------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
-
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
----
A
V
S
G
W
P
---
G
-------------------------
K
K
E
V
E
N
K
L
W
------------
S
L
S
E
Q
V
TPAVG
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.24
23%
-88
- C2 -
1KG5
6
MUTY_ECOLI
A:
[26-208]
------------------------------------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
-
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
Q
R
V
L
A
R
C
Y
----
A
V
S
G
W
P
---
G
-------------------------
K
K
E
V
E
N
K
L
W
------------
S
L
S
E
Q
V
TPAVG
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
63.05
23%
-89
- C2 -
1MUD
4
MUTY_ECOLI
A:
[26-208]
------------------------------------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
-
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
-
L
-
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
N
G
N
V
K
R
V
L
A
R
C
Y
----
A
V
S
G
W
P
---
G
-------------------------
K
K
E
V
E
N
K
L
W
------------
S
L
S
E
Q
V
TPAVG
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
------------------------------------------------------------------------------------------------------------------------------------------