@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1904: (2016-03-30 )
MKNNREKLLALFTESDGTYLSGQEIADSLGCSRTAVWKQMEALRKEGFEIEAVRNRGYRLSATAEQYTKDALLLGLETKFIGQHLEVHESVNSTQIIAHQQIETSPEGTVIVADEQTAGKGRLLRPWSSKKGEGIWMSVILKPQIPIQKVPQFTFIASLAITEAIENITKLEPKIKWPNDIYIGKRKICGVLTEMQAEAETIHAVIIGMGINVNQQEFPEEIKDKASSLKLELGESVSRKALLQEILTSLEKYYELFLDKGFAPIKLLWETKAIPFGEKLTASTTKGKIHGQVKGISDEGVLLLQDTLGEVHSIYSADILLDNEK
Atome Classification :
(40 SA)
.........10........20........30........40........50........60--------........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210..--..--.--..220.......230.......240.......250.......260.......270.......280.......290.......300.........310.......320...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKN
N
R
E
K
L
L
A
L
F
TESDGTYL
S
G
Q
E
I
A
D
S
LGC
S
R
T
A
V
W
K
Q
M
E
A
L
R
KEG
F
E
I
E
A
V
RNRG
Y
R
LS--------
A
T
A
E
Q
Y
T
K
D
A
L
LLGL
E
T
K
F
I
G
Q
H
L
E
V
H
ESVNS
T
Q
I
I
A
H
QQIETSPE
G
T
V
I
V
ADEQTAGKG
R
L
LRPWSSKKGE
G
I
W
M
S
V
I
LKPQI
P
I
Q
KVP
Q
F
T
F
I
A
S
L
A
I
T
E
A
I
E
N
I
T
KLEPKIKWPNDIYI
G
K
R
K
I
C
G
V
L
T
E
M
Q
A
E
A
E
T
I
H
A
V
I
I
GMGINV
N
--
Q
Q
--
E
--
F
P
E
E
I
K
D
K
A
S
S
L
K
L
ELG
E
S
V
S
R
K
A
L
L
Q
E
I
L
T
S
L
E
K
Y
Y
E
L
F
L
DKGFA
P
I
K
L
L
W
ETKAIPFGEKLTASTTK
G
K
I
H
G
Q
V
KGISDE
G
--
V
L
L
L
Q
D
T
L
G
E
V
H
S
I
Y
S
A
D
I
L
LDNEK
6
PsiBlast_PDB
88.27
35%
-94
- C5 -
3V7C
1
?
A:
[2-321]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
3
PsiBlast_PDB
87.82
35%
-108
- C5 -
3RKX
-
?
A:
[3-321]
--
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
9
PsiBlast_PDB
87.76
35%
-112
- C5 -
3V8J
-
?
A:
[1-320]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
---------------
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
4
PsiBlast_PDB
87.73
35%
-92
- C5 -
3RKY
1
?
A:
[2-321]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
LPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
8
PsiBlast_PDB
87.29
35%
-93
- C5 -
3V7R
1
?
A:
[8-327]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
LPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
7
PsiBlast_PDB
87.26
35%
-96
- C5 -
3V7S
1
?
A:
[2-321]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
59
HHSearch
87.25
35%
-104
- C5 -
3RKX
-
?
A:
[3-323]
--
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
--------
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
--
L
EN
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
-
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
----
12
PsiBlast_PDB
87.24
36%
-97
- C5 -
4DQ2
1
?
A:
[5-320]
-----
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
2
PsiBlast_PDB
87.13
35%
-91
- C5 -
3RKW
1
?
A:
[2-321]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
LPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
10
PsiBlast_PDB
87.08
35%
-99
- C5 -
3V8K
1
?
A:
[8-327]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
LPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
5
PsiBlast_PDB
86.99
36%
-99
- C5 -
4HA8
1
?
A:
[11-326]
-----
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
1
PsiBlast_PDB
86.93
35%
-93
- C5 -
3RIR
1
?
A:
[2-321]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
50
Fugue
86.21
33%
-105
- C5 -
3RKX
-
?
A:
[3-323]
--
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
--------
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
S
------------
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
QQ
L
E
--
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
-
N
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
----
11
PsiBlast_PDB
86.06
35%
-91
- C5 -
3V8L
1
?
A:
[8-327]
-
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
QLPDIWY
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
F
S
--------
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
D
N
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
--
Q
Q
LE
N
--
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
P
F
S
E
I
R
E
E
Y
I
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
--
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
------
13
PsiBlast_PDB
72.35
31%
-101
- C5 -
1WNL
2
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
20
PsiBlast_PDB
72.21
31%
-101
- C5 -
2DJZ
1
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
A
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
51
Fugue
71.89
33%
-96
- C5 -
1WNL
2
?
A:
[1-235]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
T
S
--
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
-
F
S
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
-----------
N
K
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
--
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
-
D
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
L
-
16
PsiBlast_PDB
71.86
31%
-101
- C5 -
1X01
1
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
30
PsiBlast_CBE
71.84
31%
-102
- C5 -
2DEQ
1
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
G
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
35
PsiBlast_CBE
71.72
31%
-102
- C5 -
2DVE
1
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
17
PsiBlast_PDB
71.70
31%
-105
- C5 -
2DKG
3
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
26
PsiBlast_CBE
71.51
31%
-101
- C5 -
1WNL
2
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
39
PsiBlast_CBE
71.39
31%
-102
- C5 -
2DXT
2
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
24
PsiBlast_CBE
71.13
31%
-97
- C5 -
1X01
3
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
18
PsiBlast_PDB
71.10
31%
-99
- C5 -
2DTH
2
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
19
PsiBlast_PDB
70.94
31%
-105
- C5 -
2DTI
3
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
34
PsiBlast_CBE
70.65
31%
-99
- C5 -
2DVE
1
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
25
PsiBlast_CBE
70.41
31%
-99
- C5 -
1WQW
1
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
21
PsiBlast_CBE
70.39
31%
-100
- C5 -
2DTI
3
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
38
PsiBlast_CBE
70.19
31%
-99
- C5 -
2DXT
2
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
23
PsiBlast_CBE
69.96
31%
-98
- C5 -
2DKG
1
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
22
PsiBlast_CBE
69.86
31%
-97
- C5 -
2DTH
2
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
32
PsiBlast_CBE
69.66
31%
-101
- C5 -
2EJG
2
?
A:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
------
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
36
PsiBlast_CBE
69.52
31%
-98
- C5 -
2DZ9
1
?
B:
[1-232]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
L
G
D
---
G
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
----
31
PsiBlast_CBE
68.74
31%
-96
- C5 -
2EJG
2
?
B:
[1-231]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
I
--------
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
---
E
V
K
K
V
I
Y
G
D
V
S
-----
33
PsiBlast_CBE
68.04
31%
-98
- C5 -
2DXU
1
?
B:
[1-226]
--------------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
--
K
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
N
Y
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
--
N
K
---------
V
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
P
M
D
I
L
N
L
V
R
D
N
M
I
L
G
V
R
V
K
--------
S
F
E
G
I
A
E
D
I
D
D
F
G
--
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
----------
40
PsiBlast_CBE
64.26
37%
-107
- C5 -
3EFS
4
?
B:
[26-225]
-------------------------------------------------------------------------------------------------------------------
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
--
Q
R
--
E
--
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
S
F
K
E
F
K
G
K
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
-
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
GA
L
I
L
T
E
E
G
I
K
E
I
L
S
------------
43
PsiBlast_CBE
64.08
36%
-104
- C5 -
3EFR
4
?
A:
[26-225]
-------------------------------------------------------------------------------------------------------------------
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
--
Q
R
--
E
--
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
S
F
K
E
F
K
G
K
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
-
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
I
K
E
I
L
S
------------
41
PsiBlast_CBE
63.93
37%
-104
- C5 -
3EFS
5
?
A:
[26-225]
-------------------------------------------------------------------------------------------------------------------
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
--
Q
R
--
E
--
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
S
F
K
E
F
K
G
K
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
-
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
I
K
E
I
L
S
------------
42
PsiBlast_CBE
63.58
36%
-101
- C5 -
3EFR
3
?
B:
[26-225]
-------------------------------------------------------------------------------------------------------------------
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
Q
E
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
--
Q
R
--
E
--
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
S
F
K
E
F
K
G
K
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
-
L
G
E
G
K
I
T
G
K
L
V
G
L
S
E
K
G
GA
L
I
L
T
E
E
G
I
K
E
I
L
S
------------