@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1920: (2016-03-30 )
LLYSLLANRAFLRLLFFGNLLGAIYGYIWYLPQLQMTEPRFWLFVPDSPTAILFFTLALVAFLGKKHWPLMEALGFVCLVKYGLWAVGMNIFYMVDQGVLVWGSVVLILTHGFMAVEGILYAPFYRFRIGHFMIAAVWVFHNDVIDYVFGQMPIYMGLEKYLPEIGYATFWLTVLVLWFVYDKTIKNKHLTLEFPHDE
Atome Classification :
(13 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-....--10....--...----.20..-------....-..-30........40-...-.---------...-.50----.-........60........70........80....--....90...-...-...100.......110.....-----..120.........130.......-140-......-..150.......160..----------.....170-......---------.180....-...190-...-...-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
Y
S
L
-
L
A
N
R
--
A
F
L
R
L
L
--
F
F
G
----
N
L
L
G
A
-------
I
Y
G
Y
-
I
W
-YLPQLQMTE
P
R
F
-
W
L
F
-V---------PDS-P
T
-----
A
-
I
L
F
F
T
L
A
L
V
A
F
LGKKH
W
P
L
M
E
A
L
G
F
V
C
L
V
K
Y
G
L
W
--
A
V
G
M
N
-
I
F
Y
-
M
VD-Q
G
V
L
V
W
G
S
V
V
L
I
L
T
H
G
F
M
A
V
E
-----
G
I
L
--YA
P
F
Y
R
F
R
I
G
H
F
M
I
A
A
V
W
V
-
F
-H-N
D
V
I
D
Y
-
V
FGQM
P
I
Y
M
G
L
E
K
Y
L
P
E----------IG
Y
A
T
F
W
L
-
T
V
L
V
L
W
---------
F
V
YDKTIK-NK
H
L
T
L
-EFP-HDE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
83.72
22%
-176
- C4 -
4RQO
1
?
A:
[20-476]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIS
V
F
D
L
F
S
I
G
I
G
PSSS
H
T
V
G
P
M
L
A
A
N
--
A
F
L
Q
L
L
--
E
Q
K
----
N
L
F
D
K
TQ
R
V
K
V
E
L
Y
G
S
-
L
A
-
L
T
G
K
G
H
G
T
D
K
A
I
-
L
N
G
-
L
E
NKAPETVD
P
A
S
M
I
P
-----
R
M
H
E
I
L
D
S
N
L
L
N
L
A
G
K
K
E
I
P
F
H
E
A
T
D
F
L
F
L
Q
K
E
L
L
P
--
K
H
S
N
G
M
R
F
S
-
A
F
D
G
N
A
N
L
L
I
E
Q
V
Y
Y
S
I
G
G
G
F
I
T
T
E
-----
E
D
F
DK
N
P
P
P
Y
P
F
A
T
A
T
E
L
L
K
L
C
K
K
-
H
-
H
-
L
T
I
A
E
L
M
L
--------------------------
V
N
E
K
T
W
R
S
-
T
A
E
I
H
K
---------
G
I
L
D
I
A
K
V
M
D
D
C
I
N
N
-
G
C
K
-
H
D
G
V
L
P
GGLNLKRR
A
P
D
L
Y
R
K
L
IFEQSD
I
M
N
H
L
N
L
Y
A
M
A
V
N
E
E
N
A
A
G
G
R
I
V
T
APTNGAAG
I
I
P
A
V
L
K
Y
C
Q
Q
A
HDRMS
N
E
D
I
Y
T
Y
F
L
T
A
A
A
I
G
I
L
Y
K
KGASISGAEVGCQGE
V
G
V
A
S
S
M
A
A
A
G
L
T
A
V
L
GGT
I
E
Q
V
E
N
A
A
E
I
A
M
E
H
H
LG
M
T
C
DPVLGLVQIP
C
I
E
R
N
A
M
G
A
V
K
A
V
N
A
T
R
M
A
L
I
G
DGQHQIS
L
D
K
V
I
K
T
M
K
Q
T
G
M
D
M
Q
SIYKETSMGGLAVNLPEC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
81.36
18%
-194
* C5 *
1K45
-
?
A:
[1-168]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
-
V
A
N
I
NG
G
F
E
S
T
P
AG
V
V
T
----
D
L
A
E
G
-------
V
E
G
W
-
D
L
-
N
V
G
S
S
V
T
N
P
P
V
F
-
E
V
L
-
E
---------
T
S
D
-
A
P
-----
E
-
G
N
K
V
L
A
V
T
V
N
G
V
G
N
N
P
W
D
-
I
E
A
T
A
F
P
V
N
V
R
P
G
V
---
T
Y
T
Y
T
-
I
W
A
-
R
A
E
-
Q
D
-----
G
A
V
V
S
F
T
V
G
N
Q
S
F
Q
-----
E
----
Y
G
R
L
H
E
Q
Q
I
T
T
E
W
Q
P
F
T
F
E
-
F
-
T
-
V
S
D
Q
E
T
-
V
I
-
R
A
P
I
H
F
G
Y
A
A
N
V
G
--------------
N
T
I
Y
I
-
D
G
L
A
I
----------------------------
A
-
S
Q
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
77.37
14%
-160
* C8 *
1Q59
-
EAR_EBVB9
A:
[1-172]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
Y
S
----
T
R
--
E
I
L
L
A
L
--
C
I
R
----
D
S
R
---------
V
H
G
N
-
G
T
-
L
H
P
V
L
E
L
A
A
R
E
T
-
P
L
R
-
L
---------
S
P
E
-
D
T
-----
V
-
V
L
R
Y
H
V
L
L
E
E
I
I
E
R
N
S
E
T
F
T
E
T
W
N
R
F
I
T
H
T
E
H
V
D
--
L
D
F
N
S
-
V
F
L
E
I
F
H
-
R
G
D
P
S
L
G
R
A
L
A
W
M
A
W
C
M
H
A
C
R
-----
T
L
C
--
C
N
Q
S
T
P
Y
Y
V
V
D
L
S
V
R
G
M
L
E
-
A
-
S
-
E
---------------
G
L
D
G
W
I
H
Q
----------
Q
G
G
---
W
S
-
T
--------------
L
I
E
D
N
I
P
G
-
D
D
D
D
L
E
-
H
H
H
-
H
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
Fugue
73.58
19%
-154
- C3 -
4DDU
3
RGYR_THEMA
A:
[2-1103]
AVN
S
K
Y
H
HSCINCGGLNT
D
E
R
N
E
R
GLPCEVCLPEDSPSD
I
Y
R
A
L
L
E
R
KTLKE
Y
R
F
Y
H
E
F
W
N
E
Y
E
D
F
R
S
F
F
K
K
K
F
G
K
D
L
T
G
Y
Q
R
L
W
A
K
R
I
V
Q
G
K
S
F
T
MVAPTGVG
K
T
T
F
G
M
M
T
A
L
W
L
A
R
K
G
K
K
S
A
L
V
F
PT
V
T
L
V
K
Q
T
L
E
R
L
Q
K
L
ADEK
V
K
I
F
G
F
Y
SSMK
K
E
E
K
E
K
F
E
K
S
F
E
EDDYH
I
L
V
F
S
T
Q
F
V
S
K
N
R
E
K
L
S
Q
KRFD
F
V
F
V
DD
V
D
A
V
L
KA
S
R
N
I
D
T
L
L
M
M
V
-
G
I
P
E
--
E
I
I
R
K
A
--
F
S
T
----
I
K
Q
G
K
-------
I
Y
--------
E
R
P
K
N
L
K
P
G
I
-
L
V
V
-
S
---------
S
A
T
-
A
K
-----
P
-
R
G
I
R
P
L
L
F
R
D
L
L
N
F
T
V
G
R
L
V
S
V
A
R
N
I
T
H
V
R
I
S
S
R
S
K
E
K
L
V
E
-
L
L
E
-
I
F
R
-
D
G
I
L
I
F
A
Q
T
--------
E
E
E
G
-----
K
E
L
--
Y
E
Y
L
K
R
F
---
K
F
N
V
G
E
T
W
S
E
F
-
E
-
K
N
F
E
D
F
-
K
V
G
K
I
N
I
L
I
G
V
Q
A
Y
Y
G
K
L
TRGVDLPER
I
K
Y
V
I
F
W
G
-
T
P
S
M
R
F
S
LELDKAP
R
F
V
L
A
R
V
L
K
-
E
M
G
L
I
K
-
A
Q
E
-
N
P
D
V
E
E
L
R
K
I
A
KEHLT
Q
K
E
F
V
E
K
V
K
E
M
FRGVVVKDEDL
E
L
I
I
P
D
V
Y
T
Y
I
Q
A
S
G
RSSRILNGVL
V
K
G
V
S
V
I
F
E
ED
E
E
I
F
E
S
L
K
T
R
L
L
L
IAE
E
E
I
I
E
EAEAN
W
K
E
L
V
H
E
V
E
E
S
R
R
R
S
E
R
E
L
T
D
T
S
R
S
L
L
I
I
V
E
S
P
T
K
A
E
T
L
S
R
F
L
GRA
S
S
R
K
E
RN
I
I
V
H
E
A
V
T
GE
G
V
I
L
F
T
A
TRGHVYDLVTKGGIHG
V
E
E
E
NG
K
F
V
P
V
Y
N
S
L
K
R
C
RDCGYQFTEDRDECPVCSSKNIDD
K
T
E
T
L
R
A
L
R
E
I
S
L
E
AD
E
I
L
V
A
T
D
PD
V
E
G
E
K
I
S
W
D
V
T
Q
Y
L
L
PSTR
S
L
R
R
I
E
M
HEIT
R
Y
G
F
K
K
A
R
E
S
VRFVD
F
N
L
V
K
A
Q
I
V
R
R
V
Q
D
R
W
I
G
F
E
L
S
G
K
L
Q
K
R
FGRSNLSAG
R
V
Q
S
T
V
L
G
W
I
V
E
R
E
E
E
Y
K
K
S
E
K
D
F
T
L
L
V
L
E
N
G
V
N
L
E
V
E
G
KIADD
V
V
T
V
V
E
L
Q
E
A
E
E
E
K
N
P
L
P
P
YT
T
S
S
A
L
S
E
I
S
Q
K
L
RLG
V
Q
E
V
M
D
I
L
Q
D
L
F
E
K
GFITYHRTDSTRIS
L
E
G
Q
N
V
A
R
T
Y
L
R
K
I
GKEDI
F
M
G
R
SWSTEGAHEAIRPVKPID
A
R
E
L
E
E
M
I
E
E
GLIADLT
K
K
H
L
R
V
Y
E
L
I
F
N
R
F
L
A
S
Q
S
A
A
V
K
V
K
K
Q
I
V
T
V
D
V
DG
K
R
M
G
I
E
Q
I
V
E
ILRDGWNLF
V
P
L
T
V
S
P
R
F
E
H
R
T
Y
K
I
K
E
K
K
F
Y
K
K
H
T
V
P
L
F
T
Q
A
S
I
V
E
E
M
K
K
R
GIGRPST
Y
A
K
I
V
E
V
L
F
R
R
GY
V
Y
E
D
KYK
R
V
R
P
T
R
F
G
V
M
V
Y
S
Y
L
K
E
RYEKYVT
E
E
T
T
R
R
L
E
E
I
M
D
K
V
E
R
GEED
Y
Q
A
T
L
R
L
L
Y
E
E
I
K
S
L
M
E
E
15
Fugue
62.49
19%
-129
- C5 -
4B9G
-
CSSA1_ECOLX (first)
A:
[16-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
-
D
S
A
V
--
R
I
I
P
V
N
--
Y
D
S
----
D
P
------------
K
L
-
N
S
-
Q
L
Y
T
V
E
M
T
I
P
A
G
-
V
S
A
-
V
---------
K
I
V
-
P
T
-----
D
-
S
L
T
S
S
G
Q
Q
I
G
K
L
V
N
V
N
N
P
--------------------
D
Q
N
-
M
N
Y
-
Y
I
R
-
K
D
S
-----------------------------------
G
A
G
K
F
M
A
G
Q
K
G
S
-
F
-
S
V
K
E
N
T
S
Y
-
T
F
--
S
A
I
Y
T
G
G
E
Y
P
N
S
G
----------
Y
S
S
G
T
Y
A
G
-
H
L
T
V
S
F
---------
Y
S
N
D
N
K
Q
R
-
T
E
I
A
T
K
-
N
F
P
-
V
S
T
T
I
S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
53.36
10%
-121
- C8 -
3IC6
-
?
A:
[4-220]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
P
A
L
-
P
D
Y
L
--
G
N
I
R
I
I
--
L
T
R
TSH
P
A
N
I
G
S
-------
A
A
R
A
M
K
T
M
G
L
H
R
L
T
I
V
T
P
N
L
M
A
T
P
M
T
---------
E
N
P
-
P
V
F
N
PDD
V
-
Q
S
F
A
L
P
E
E
S
F
I
L
A
S
G
A
A
D
V
L
H
N
A
E
I
V
A
T
L
D
E
A
L
A
--
D
T
T
I
A
-
C
A
L
-
T
S
R
-
R
R
T
A
P
L
Q
T
P
R
D
L
V
P
E
L
L
Q
A
A
N
R
G
E
K
V
A
L
V
--
F
G
N
-
E
T
F
G
L
S
I
E
E
V
R
A
C
N
R
-
L
M
T
-
I
N
G
-
N
P
-
D
Y
F
S
L
N
L
A
Q
A
V
Q
V
V
C
Y
E
----------
I
F
S
Q
T
D
S
P
M
T
H
L
Q
--------------
Q
H
A
A
T
-
H
E
Q
I
K
G
M
L
A
H
M
E
S
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
41.05
35%
-58
* C6 *
3MWC
-
?
A:
[346-390]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
K
-
G
N
-
D
L
V
E
N
T
M
T
D
G
K
---
I
Y
-
V
---------
P
D
E
-
P
G
-----
A
-
S
F
D
M
T
L
S
H
L
E
A
L
G
K
K
I
W
E
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
32.75
11%
88
- C6 -
2JP3
-
FXYD4_RAT
A:
[27-54]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
-
C
I
A
G
I
A
---------
L
A
L
S
G
K
C
K
-
C
R
R
N
H
T
-
P
S
S
-
L
P
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
23.91
0%
1047
- C2 -
2KLU
-
CD4_HUMAN
A:
[392-398]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
S
V
R
S
-
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
17.81
25%
322
- C7 -
2FE0
-
?
A:
[46-61]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
W
A
-
Y
-
Y
-
N
D
T
T
Q
Y
-
E
M
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
17.57
25%
307
* C7 *
1R75
-
?
A:
[43-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
W
A
-
F
-
Y
-
N
D
S
K
E
L
-
I
I
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
14.30
50%
-
- C7 -
2GSX
-
CR2_HUMAN
A:
[853-876]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
S
-
I
L
Y
-
S
C
D
-
Q
G
Y
L
L
V
G
E
A
L
L
L
C
T
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
5.14
67%
1222
- C1 -
2HFR
-
A:
[3-8]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-
W
P
L
-
V
---------
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------