@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1929: (2016-03-30 )
MEQTYVMVKPDGVERGLIGEIVTRIEKKGLKIVAGKLMQIDRELAEKHYAEHIGKSFFEDLIGFITSGPVFAMVLEGDDAIATARRMMGKTNPLEADPGTIRADYAIHTNRNVIHGSDSPESAQREIQLFFAPDEILSYQKAVDTWI
Atome Classification :
(58 SA)
--.........10........20........30........-40........50........60........70........80........90........100.....---..110-.........120.......130.......140.....--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MEQ
T
Y
V
M
VKPDGVER
G
L
I
G
E
I
V
T
R
I
E
KKG
L
K
I
V
A
G
K
L
M
Q
-
I
D
R
E
L
A
E
K
H
Y
A
E
H
I
G
K
S
F
F
E
D
L
I
G
F
ITSG
P
V
F
A
M
V
LEGD
D
A
I
A
T
A
R
R
MMGKTNPLEADP
G
T
I
R
A
D
Y
A
I
---HTN---RNVIHGSDS
P
E
S
A
Q
R
E
I
Q
L
F
FA
P
D
E
I
L
S
Y
Q
K
A
V
D
TWI--
7
PsiBlast_PDB
95.14
63%
-107
- C9 -
3VVT
-
?
A:
[1-139]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
S
R
F
E
R
K
G
L
K
I
V
A
M
K
M
M
R
-
I
S
R
E
M
A
E
K
H
Y
A
E
H
R
E
K
P
F
F
S
A
L
V
D
Y
I
T
S
G
P
V
V
A
M
V
L
E
G
K
N
A
V
E
V
V
R
K
M
V
G
A
T
N
P
K
E
A
A
P
G
T
I
R
G
D
F
G
L
---
D
V
G
---
K
N
V
I
H
A
S
D
S
P
E
S
A
E
R
E
I
S
L
F
F
K
D
E
E
L
V
E
W
----------
22
PsiBlast_CBE
95.12
59%
-101
- C9 -
3Q8Y
2
NDK_STAAC
G:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
23
PsiBlast_CBE
94.66
59%
-103
- C9 -
3Q8Y
1
NDK_STAAC
F:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
28
PsiBlast_CBE
94.48
59%
-100
- C9 -
3Q8V
2
NDK_STAAC
D:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
26
PsiBlast_CBE
94.24
59%
-101
- C9 -
3Q8Y
1
NDK_STAAC
C:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
132
HHSearch
94.17
58%
-99
- C9 -
2DXE
3
NDK_PYRHO
A:
[7-155]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
EVS
D
A
I
---
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
W
F
---
1
PsiBlast_PDB
94.16
59%
-100
- C9 -
3Q83
-
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
37
PsiBlast_CBE
93.98
59%
-97
- C9 -
3Q86
1
NDK_STAAC
B:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
126
HHSearch
93.92
60%
-97
- C9 -
3Q8U
2
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
76
PsiBlast_CBE
93.88
57%
-99
- C9 -
2DY9
4
NDK_PYRHO
A:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
78
PsiBlast_CBE
93.76
57%
-100
- C9 -
2DXF
2
NDK_PYRHO
A:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
25
PsiBlast_CBE
93.65
59%
-100
- C9 -
3Q8Y
3
NDK_STAAC
D:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
80
PsiBlast_CBE
93.63
57%
-98
- C9 -
2DXE
3
NDK_PYRHO
A:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
77
PsiBlast_CBE
93.62
57%
-100
- C9 -
2DXF
2
NDK_PYRHO
B:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
82
PsiBlast_CBE
93.61
57%
-101
- C9 -
2DXD
2
NDK_PYRHO
A:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
15
PsiBlast_PDB
93.61
62%
-109
- C9 -
1WKL
2
NDK_THET8
A:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
------------
74
PsiBlast_CBE
93.55
57%
-97
- C9 -
2DYA
4
NDK_PYRHO
A:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
4
PsiBlast_PDB
93.55
59%
-97
- C9 -
3Q8U
2
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
14
PsiBlast_PDB
93.51
62%
-103
- C9 -
1WKK
1
NDK_THET8
A:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
------------
81
PsiBlast_CBE
93.46
57%
-99
- C9 -
2DXD
2
NDK_PYRHO
B:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
6
PsiBlast_PDB
93.37
59%
-101
- C9 -
3Q8Y
2
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
29
PsiBlast_CBE
93.29
59%
-97
- C9 -
3Q8V
2
NDK_STAAC
B:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
35
PsiBlast_CBE
93.21
59%
-98
- C9 -
3Q89
2
NDK_STAAC
E:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
2
PsiBlast_PDB
93.14
59%
-97
- C9 -
3Q86
2
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
21
PsiBlast_CBE
93.13
59%
-102
- C9 -
3Q8Y
3
NDK_STAAC
H:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
24
PsiBlast_CBE
93.07
59%
-101
- C9 -
3Q8Y
2
NDK_STAAC
E:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
5
PsiBlast_PDB
93.00
59%
-97
- C9 -
3Q8V
2
NDK_STAAC
A:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
32
PsiBlast_CBE
92.99
59%
-98
- C9 -
3Q8U
2
NDK_STAAC
D:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
45
PsiBlast_CBE
92.98
62%
-108
- C9 -
1WKL
2
NDK_THET8
B:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
---
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
------------
31
PsiBlast_CBE
92.98
59%
-101
- C9 -
3Q8U
2
NDK_STAAC
E:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
36
PsiBlast_CBE
92.73
59%
-96
- C9 -
3Q89
2
NDK_STAAC
B:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
34
PsiBlast_CBE
92.73
59%
-95
- C9 -
3Q8U
2
NDK_STAAC
B:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
30
PsiBlast_CBE
92.69
59%
-96
- C9 -
3Q8U
2
NDK_STAAC
F:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
73
PsiBlast_CBE
92.65
57%
-98
- C9 -
2DYA
5
NDK_PYRHO
B:
[8-153]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
DAI
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-----
27
PsiBlast_CBE
92.53
59%
-101
- C9 -
3Q8Y
2
NDK_STAAC
B:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
33
PsiBlast_CBE
92.06
59%
-95
- C9 -
3Q8U
1
NDK_STAAC
C:
[1-147]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
---
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
--
98
PsiBlast_CBE
90.07
55%
-97
- C9 -
1HIY
1
NDKC_DICDI
B:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
85
PsiBlast_CBE
89.97
55%
-99
- C9 -
2BEF
2
NDKC_DICDI
C:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
94
PsiBlast_CBE
89.58
55%
-96
- C9 -
1KDN
2
NDKC_DICDI
C:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
95
PsiBlast_CBE
89.54
55%
-96
- C9 -
1KDN
2
NDKC_DICDI
B:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
100
PsiBlast_CBE
89.19
55%
-94
- C9 -
1F6T
2
NDKC_DICDI
C:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
96
PsiBlast_CBE
88.99
55%
-95
- C9 -
1KDN
2
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
87
PsiBlast_CBE
88.97
55%
-96
- C9 -
2BEF
2
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
90
PsiBlast_CBE
88.74
55%
-99
- C9 -
1S5Z
1
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
91
PsiBlast_CBE
88.69
55%
-100
- C9 -
1NDP
1
NDKC_DICDI
B:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
86
PsiBlast_CBE
88.54
55%
-97
- C9 -
2BEF
2
NDKC_DICDI
B:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
93
PsiBlast_CBE
88.52
55%
-97
- C9 -
1NDC
2
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
38
PsiBlast_CBE
88.46
53%
-97
- C9 -
1S59
1
NDK2_ARATH
C:
[5-151]
--
V
E
E
T
Y
I
M
V
K
P
D
G
I
Q
R
G
L
V
G
E
I
I
S
R
F
E
K
K
G
F
K
L
I
G
L
K
M
F
Q
-
C
P
K
E
L
A
E
E
H
Y
K
D
L
S
A
K
S
F
F
P
N
L
I
E
Y
I
T
S
G
P
V
V
C
M
A
W
E
G
V
G
V
V
A
S
A
R
K
L
I
G
K
T
D
P
L
Q
A
E
P
G
T
I
R
G
D
L
A
V
---
Q
T
G
---
R
N
I
V
H
G
S
D
S
P
E
N
G
K
R
E
I
G
L
W
F
K
E
G
E
L
C
K
W
D
S
A
L
A
T
W
L
--
97
PsiBlast_CBE
88.32
55%
-102
- C9 -
1HIY
1
NDKC_DICDI
C:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
99
PsiBlast_CBE
88.08
55%
-94
- C9 -
1HIY
1
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
92
PsiBlast_CBE
88.00
55%
-91
- C9 -
1NDP
1
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
102
PsiBlast_CBE
87.49
55%
-94
- C9 -
1F6T
2
NDKC_DICDI
A:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
103
Fugue
87.41
53%
-89
- C9 -
1NDP
1
NDKC_DICDI
A:
[6-155]
VN
K
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
N
-
P
N
L
YE
101
PsiBlast_CBE
87.22
55%
-92
- C9 -
1F6T
2
NDKC_DICDI
B:
[9-148]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
---
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
--------
11
PsiBlast_PDB
86.97
53%
-96
- C9 -
1S59
1
NDK2_ARATH
A:
[5-151]
--
V
E
E
T
Y
I
M
V
K
P
D
G
I
Q
R
G
L
V
G
E
I
I
S
R
F
E
K
K
G
F
K
L
I
G
L
K
M
F
Q
-
C
P
K
E
L
A
E
E
H
Y
K
D
L
S
A
K
S
F
F
P
N
L
I
E
Y
I
T
S
G
P
V
V
C
M
A
W
E
G
V
G
V
V
A
S
A
R
K
L
I
G
K
T
D
P
L
Q
A
E
P
G
T
I
R
G
D
L
A
V
---
Q
T
G
---
R
N
I
V
H
G
S
D
S
P
E
N
G
K
R
E
I
G
L
W
F
K
E
G
E
L
C
K
W
D
S
A
L
A
T
W
L
--
127
HHSearch
86.04
50%
-94
- C9 -
1ZS6
1
NDK3_HUMAN
A:
[21-167]
--
H
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
---
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
C
W
E
D
S
A
G
H
W
L
--
133
HHSearch
82.71
47%
-97
- C9 -
3EVO
1
NDK_MIMIV
A:
[6-138]
--
L
Q
R
T
L
V
L
I
K
P
D
A
F
E
R
S
L
V
A
E
I
M
G
R
I
E
K
K
N
F
K
I
V
S
M
K
F
W
S
K
A
P
R
N
L
I
E
Q
H
Y
K
E
H
S
E
Q
S
Y
F
N
D
N
C
D
F
M
V
S
G
P
I
I
S
I
V
Y
E
G
T
D
A
I
S
K
I
R
R
L
Q
G
N
T
N
P
L
A
S
A
P
G
T
I
R
G
D
L
A
N
---
D
I
R
---
E
N
L
I
H
A
S
D
S
E
D
S
A
V
D
E
I
S
I
W
F
P
-----------------
129
HHSearch
82.39
49%
-92
- C9 -
1NHK
1
NDK_MYXXA
R:
[2-142]
--
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
---
K
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
S
Y
P
Y
--------