@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1975: (2016-03-30 )
MDTSRKIIHIDMDAFYASVEQRDHPEFRGKPLIIGGDPNKRGVVATCSYEARKFGVHSAMPTRQAAKLCPNGIFIHGNMAHYVEVSNQIREIFSRYTDIIEPLSLDEAYLDVTENKKGMKSATMVAREIQQTIYQELGLTASAGVSFNKFIAKIASDFKKPAGITVVTPEEAEAFLEQIPVTKFYGVGKVTAEKLHRLGIETGADLKKWSEWDLIRELHKHGYHLYRHVRGRSNNIVNPHRDRKSVGKETTFEFNVLDSRVLEQSLMQFAKKVEERLIKLQKHGKTVVLKLRYSDFTTITKRLTLNEYTNDASQIYQAAALLLIESYTGQDSIRLIGLTVTNLKPVYFENLRLEGL
Atome Classification :
(84 SA)
----------------------------------------------------------------.........10........20........30...---.....40........50........60........70........80........90........100.......110......-.120------------------.........130.......140.......150.......160.......--170.......180.......190.......200....--...210......--.220.......230.......240.......250.......260.......270.......280-----........290.......300.......310.......320......----.330--.........340.......350....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------MDTSR
K
I
I
H
I
D
M
D
A
F
Y
A
S
V
EQRDHPEFRG
K
P
L
I
I---GGDPNK
R
G
V
V
A
T
CS
Y
E
A
R
KFGVHSAM
P
T
R
Q
A
A
K
LCP
N
G
I
F
IHGN
M
A
H
Y
V
E
V
S
N
Q
I
R
E
I
F
S
R
Y
T
D
I
IEPLSL
D
E
A
Y
L
D
VTENKKG-
M
K
--------------------
S
A
T
M
V
A
R
E
I
Q
Q
T
I
Y
Q
E
LGLTASAGV
S
F
N
K
F
I
A
K
I
A
S
D
FKKPA
G
I
T
V
V
T
P
--
E
E
A
E
A
F
L
E
QIPV
T
K
F
YGV
G
K
V
T
A
E
K
L
H
R
LGIETGADL--KKW
S
E
W
D
L
I
R
E
L
--
H
KH
G
Y
H
L
Y
R
H
VRGRSNNIVNP
H
R
D
R
K
SVGKE
T
T
F
E
F
NV
L
D
S
R
V
L
E
Q
S
L
M
Q
F
A
K
K
V
E
E
R
L
I
K
L
Q
------KHG
K
T
V
V
L
K
L
RYSD
F
T
T
I
T
K
R
L
T
LNEYT
N
D
A
S
Q
I
Y
Q
A
A
A
L
L
L
I
ESYT----GQ----D
S
I
R
L
I
G
L
T
VTNLK
P
V
Y
F
E
N
L
RLEGL
8
PsiBlast_PDB
94.48
45%
-92
- C3 -
4Q44
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
9
PsiBlast_PDB
94.41
45%
-91
- C3 -
4Q45
5
DPO4_ECOLI
F:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
26
PsiBlast_CBE
94.32
45%
-93
- C3 -
4IRK
4
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
25
PsiBlast_CBE
93.69
45%
-91
- C3 -
4Q44
5
DPO4_ECOLI
F:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
29
PsiBlast_CBE
93.67
45%
-96
- C3 -
4R8U
4
?
B:
[1-336]
--------------------------------------------------------------------
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
---------------
7
PsiBlast_PDB
93.60
45%
-91
- C3 -
4IRK
6
DPO4_ECOLI
B:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
4
PsiBlast_PDB
93.60
45%
-93
- C3 -
4R8U
4
DPO4_ECOLI
A:
[1-339]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
-------------
21
PsiBlast_CBE
93.58
45%
-86
- C3 -
4Q43
5
DPO4_ECOLI
F:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
27
PsiBlast_CBE
93.45
45%
-92
- C3 -
4IRD
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
3
PsiBlast_PDB
93.29
45%
-90
- C3 -
4Q43
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
28
PsiBlast_CBE
93.20
45%
-90
- C3 -
4IRC
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
5
PsiBlast_PDB
93.15
45%
-87
- C3 -
4IRC
5
DPO4_ECOLI
F:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
22
PsiBlast_CBE
93.05
45%
-92
- C3 -
4IR9
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
24
PsiBlast_CBE
92.98
45%
-90
- C3 -
4Q45
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
A
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
A
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
1
PsiBlast_PDB
92.98
45%
-89
- C3 -
4IR1
5
DPO4_ECOLI
F:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R
K
S
V
G
V
E
R
T
M
A
E
D
I
H
H
W
S
E
C
E
A
I
I
E
R
L
Y
P
E
L
E
R
R
L
A
K
V
K
PDLLIA
R
Q
G
----
V
K
L
K
F
D
D
F
Q
Q
T
T
Q
E
H
V
W
P
R
L
-
N
K
A
D
L
I
--
A
T
A
R
K
T
W
D
E
R
R
----
G
G
----
R
G
V
R
L
V
G
L
H
V
T
L
L
D
P
-----------
23
PsiBlast_CBE
92.70
45%
-90
- C3 -
4IR1
7
DPO4_ECOLI
A:
[2-342]
-------------------------------------------------------------------
S
R
K
I
I
H
V
D
M
D
C
F
F
A
A
V
E
M
R
D
N
P
A
L
R
D
I
P
I
A
I
---
G
G
S
R
E
R
R
G
V
I
S
T
A
N
Y
P
A
R
K
F
G
V
R
S
A
M
P
T
G
M
A
L
K
L
C
P
H
L
T
L
L
P
G
R
F
D
A
Y
K
E
A
S
N
H
I
R
E
I
F
S
R
Y
T
S
R
I
E
P
L
S
L
D
E
A
Y
L
D
V
T
D
S
V
H
C
-
H
G
--------------------
S
A
T
L
I
A
Q
E
I
R
Q
T
I
F
N
E
L
Q
L
T
A
S
A
G
V
A
P
V
K
F
L
A
K
I
A
S
D
M
N
K
P
N
G
Q
F
V
I
T
P
--
A
E
V
P
A
F
L
Q
T
L
P
L
A
K
I
P
G
V
G
K
V
S
A
A
K
L
E
A
M
G
L
R
T
C
G
D
V
--
Q
K
C
D
L
V
M
L
L
K
R
F
--
G
K
F
G
R
I
L
W
E
R
S
Q
G
I
D
E
R
D
V
N
S
E
R
L
R