@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2010: (2016-03-31 )
MLKIVLVDDEPLILKGLESIIPEFEQSIEIIGTAKNGAVALDLFANQEVDVLLTDIEMPVMNGLELIDEWKKRQPATKTIVLSGFEDFHYVKRGLSAGIENYLLKPLNEQELKETLIQIEKKQMTDSVIPREEAYYILRDNTIWRWLNLRINKEEWEERLALYDMALNPKENAVLIQIQATKEIDLAEWKNLSEQYRKDFSFMLLTPENEIIVGITEQTSISEQILAIHQDMKKRISNEAFYLFISEKVQGEMMYPQAFRQLTRLLPERLVQEPGSLIAYQKRTKHTWRPKRKQHQLAKLLVMNNEKEIKAWINNFFKEWNDHKLESDPHQMLHILNELLVMMAESDPKELSESMGRIAEETSIEGLEEATLAYAIRYYNRKKQTDESKSPIIQNVLSYITEHFAEGMSLKTLGNDFHINAVYLGQLFQKEMGEHFTDYLNRYRVNYAKEELLQTKDNLTIIAGKSGYTDMAYFYRQFKKHTGETPNRYRKIHQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
K
I
V
L
VDDE
P
L
I
L
K
G
L
E
S
I
I
P
E
F
E
Q
S
I
E
I
I
G
TAKN
G
A
V
A
L
D
L
FANQE
V
D
V
L
L
TDIE
M
P
V
M
N
G
L
E
L
I
D
E
W
K
KRQPAT
K
T
I
V
LSG
F
E
D
F
H
Y
V
K
R
G
L
S
A
G
I
E
N
Y
L
LKPL
N
E
Q
E
L
K
E
T
L
I
Q
I
E
K
K
QMTDSVIPRE
E
A
Y
Y
I
L
RDN
T
I
W
R
W
L
N
L
R
I
N
K
E
E
W
E
E
R
L
A
L
Y
DMALNPKE
N
A
V
L
I
Q
I
Q
ATKEI
D
L
A
E
W
K
N
L
S
E
Q
Y
R
KDF
S
F
M
L
LTPEN
E
I
I
V
G
ITEQT
S
I
S
E
Q
I
L
A
I
H
Q
D
M
K
K
RISNE
A
F
Y
L
F
ISEKVQGEMM
Y
P
Q
A
F
R
Q
L
T
R
L
L
P
E
R
L
V
QEPG
S
L
I
A
Y
Q
KRTKHTWRP
K
R
K
Q
H
Q
L
A
K
L
L
VMN
N
E
K
E
I
K
A
W
I
N
N
F
F
K
EWNDHKLES
D
P
H
Q
M
L
H
I
L
N
E
L
L
V
M
MAES
D
P
K
E
L
S
E
S
M
G
R
I
A
E
E
TSIE
G
L
E
E
A
T
L
A
Y
A
I
R
Y
YNRKKQTDESKS
P
I
I
Q
N
V
L
S
Y
I
T
E
H
F
AEGM
S
L
KTLGND
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
QTKD
N
L
T
I
I
AGKSGY
T
D
M
A
Y
F
Y
R
Q
F
K
K
HTGET
P
N
R
Y
R
K
IHQ
46
HHSearch
80.63
99%
-59
- C5 -
3OOU
1
?
A:
[4-108]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
I
Q
N
V
L
S
Y
I
T
E
H
F
S
E
G
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
E
T
P
N
R
Y
R
K
I
H
Q
1
PsiBlast_PDB
79.96
96%
-59
- C5 -
3OOU
1
?
A:
[4-108]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
I
Q
N
V
L
S
Y
I
T
E
H
F
S
E
G
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
E
T
P
N
R
Y
R
K
I
H
Q
72
Fugue
78.12
15%
-51
- C2 -
1NY5
8
?
A:
[1-384]
-
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
M
K
G
I
K
V
E
S
A
---
E
R
G
K
E
A
Y
K
L
L
S
E
K
H
F
N
V
V
L
L
D
L
L
L
P
D
V
N
G
L
E
I
L
K
W
I
K
E
R
S
P
E
T
E
V
I
V
I
T
G
H
G
T
I
K
T
A
V
E
A
M
K
M
G
A
Y
D
F
L
T
K
P
C
M
L
E
E
I
E
L
T
I
N
K
A
I
E
H
R
K
L
R
K
E
N
E
L
L
R
R
E
K
D
L
K
E
E
E
Y
----------------------------------------------
V
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
S
C
A
E
C
P
V
L
I
T
G
E
S
G
V
G
K
E
V
V
A
R
L
I
H
K
L
S
D
R
S
K
E
P
F
V
A
L
N
V
A
S
I
P
R
D
I
F
E
A
E
L
F
G
Y
E
K
G
A
F
T
G
A
V
S
S
K
E
G
F
F
E
L
A
D
G
G
T
L
F
L
D
-------
E
I
G
E
L
-----
S
L
E
A
Q
A
K
L
L
R
V
I
E
S
G
K
F
Y
R
L
G
G
R
K
E
I
E
V
N
V
---
R
I
L
A
A
T
N
R
N
I
K
E
L
V
K
-----------
E
G
K
F
R
E
D
L
Y
Y
R
L
G
V
I
E
I
E
I
P
P
L
R
E
R
K
E
D
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
A
K
E
V
-----------------
E
G
F
T
K
S
A
Q
E
L
L
L
S
Y
P
W
Y
G
N
V
R
E
L
K
N
V
I
E
R
A
V
L
F
S
E
G
K
F
I
D
R
G
E
L
S
C
L
V
-----------------
11
PsiBlast_PDB
73.71
30%
-74
- C4 -
3TMY
1
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
72.46
29%
-70
- C4 -
1U0S
-
CHEY_THEMA
Y:
[4-118]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
72.35
32%
-80
- C4 -
4LDZ
5
DESR_BACSU
B:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
72.16
32%
-79
- C4 -
4LE2
4
DESR_BACSU
C:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
72.06
32%
-81
- C4 -
4LDZ
5
DESR_BACSU
A:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
71.94
32%
-81
- C4 -
4LE2
3
DESR_BACSU
A:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
71.84
29%
-74
- C4 -
4QYW
-
?
A:
[3-118]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
-
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
A
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
71.82
30%
-68
- C4 -
4IGA
3
CHEY_THEMA
A:
[7-121]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
71.66
30%
-70
- C4 -
4TMY
1
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
71.27
32%
-89
- C4 -
4LE2
1
DESR_BACSU
D:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
----
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.00
32%
-79
- C4 -
4LE0
3
DESR_BACSU
A:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
70.86
32%
-82
- C4 -
4LE0
4
DESR_BACSU
B:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
A
R
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.72
30%
-66
- C4 -
1TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
70.70
32%
-85
- C4 -
4LE2
2
DESR_BACSU
B:
[5-117]
M
I
S
I
F
I
A
E
D
Q
Q
M
L
L
G
A
L
G
S
L
L
-
N
L
E
D
D
M
E
V
V
G
K
G
T
T
G
Q
D
A
V
D
F
V
K
K
R
Q
P
D
V
C
I
M
D
I
E
M
P
G
K
T
G
L
E
A
A
E
E
L
K
--
D
T
G
C
K
I
I
I
L
T
T
F
--
P
G
Y
F
Q
R
A
I
K
A
G
V
K
G
Y
L
L
K
D
S
P
S
E
E
L
A
N
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
70.65
27%
-66
- C4 -
4IF4
3
VRAR_STAAM
A:
[2-115]
-
I
K
V
L
F
V
D
D
H
E
M
V
R
I
G
I
S
S
Y
L
S
T
-
Q
S
D
I
E
V
V
G
E
G
A
S
G
K
E
A
I
A
K
A
H
E
L
K
P
D
L
I
L
M
D
L
L
M
E
D
M
D
G
V
E
A
T
T
Q
I
K
K
D
L
P
Q
I
K
V
L
M
L
T
S
F
I
E
D
K
E
V
Y
R
A
L
D
A
G
V
D
S
Y
I
L
K
T
T
S
A
K
D
I
A
D
A
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
70.22
36%
-60
- C4 -
3A0U
5
?
A:
[1-111]
M
K
R
I
L
V
V
D
D
E
P
N
I
R
E
L
L
K
E
E
L
Q
E
E
G
Y
E
I
D
---
T
A
E
N
G
E
E
A
L
K
K
F
F
S
G
N
Y
D
L
V
I
L
D
I
E
M
P
G
I
S
G
L
E
V
A
G
E
I
R
K
K
K
K
D
A
K
I
I
L
L
T
A
Y
S
--
H
Y
R
S
D
L
S
S
W
A
A
D
E
Y
V
V
K
S
F
N
F
D
E
L
K
E
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
70.16
30%
-64
- C4 -
2TMY
-
CHEY_THEMA
A:
[4-119]
--
R
V
L
I
V
D
D
A
A
F
M
R
M
M
L
K
D
I
I
T
K
--
A
G
Y
E
V
A
G
E
A
T
N
G
R
E
A
V
E
K
Y
K
E
L
K
P
D
I
V
T
M
D
I
T
M
P
E
M
N
G
I
D
A
I
K
E
I
M
K
I
D
P
N
A
K
I
I
V
C
S
A
M
G
Q
Q
A
M
V
I
E
A
I
K
A
G
A
K
D
F
I
V
K
P
F
Q
P
S
R
V
V
E
A
L
N
K
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------