@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Lmo2023: (2016-03-31 )
MIKERVIIVGSGISGCTAALRLMQDYDVTIITKGYKEESNSMLAQGGVAAAVSKNDTPKKHFSDTFQAGCFHNKVLAVNQLVTHGPMVIQKLIAEGMAFDEQDGELALGLEGAHQLPRILHTGGDQTGKFLTTFLQEKLTDIHWQEQKMAIEIIKQNDSAIGVHCLDKENRLHTYYGEHIILASGGLGQLFPVTTNAATISGDGLALAYRAGAKLTDMEFIQFHPTLLFLNGRCHGLISEAVRGEGAKLIRADGSAIMTDVHPRADLAPRDIVAATLFAEIQDGNEVFLDITAIPNFEKRFPGITANLDAHHIPFRETKRIPVHPGAHFLMGGIRTDLSGKTNIPGLYAIGEVANAGVHGANRLASNSLLETLVFGEKVAEYIRTQKINPIDHPEIPLSNQIQTPHLPDKQLLQEKIWETLGITRKPEKITEFLHWLTDFDYANHTRKTAEISHMLITAKLIAESALKRTESLGAHRILKGVIK

Atome Classification :

(24 SA) ---------------------------------------------------------------------------------------------------------------------------.........10........20...-.--....30.-.......40........50.-----.--.-------.....60........70........80........90........100-.-.-.----------------------....---------------------..110.....-------.--------...120...---------....-.130-....------------....---140-.--........150.....-------.-------.---------160......-.-.170-........180.......190.------------......200.......210-.......220.......230.......240.......250..--------------.....260--------..-.------------.-....270.....-..280.-------.--------.--------.--------...290..--.--.--...300...------..-.-.310-.--.......320---------------------.........330.......340---------.---------.......350.......360.......370.......380......-------.390.-.----.------..-----.-----.400-.........---------410.---------..---.-------..------------.420.......430.......440---.--------------..--------.--------------.-....450-.........460.......470....----------...480....----------------------------------------------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) ---------------------------------------------------------------------------------------------------------------------------MIKERVIIVGSGISGCTAALRLMQ-D--YDVTIIT-KGYKEESNSMLAQGGVAAAV-----S--K-------NDTPKKHFSDTFQAGCFHNKVLAVNQLVTHGPMVIQKLIAEGMAFD---E-Q-D----------------------GELA---------------------LGL--EGAHQ-------L--------PRIL-HTGG---------DQTG-KFL--TTFL------------QEKL---T---D--IHWQEQKMAIEIIKQN-------D-------S---------AI-GVHCLD-K-EN-R-LHTYYGEHIILASGGLGQLFPV------------TTNAATISGDGLALAYRAG-AKLTDMEFIQFHPTLLFLNGRCHGLISEAVRGEGAKLIRADG--------------SAIMTDV---------HP-R------------A-DLAPRDIVAATL-FAEIQD-------G--------N--------E--------VFLDITAI--P--N--FEKRFPGIT------AN-L-DA-H-H--IPFRETKR-----------------------IPVHPGAHFLMGGIRTDLSGK----------T---------NIPGLYAIGEVANAGVHGANRLASNSLLETLVFGEKVAEYIRTQKI-------NPIDH-P----E------IP-----L-----SN---QIQTPHLPD---------KQLL---------QE---K-------IW------------ETLGITRKPEKITEFLHWLTDF-----D--------------YA--------N--------------H-TRKTA---EISHMLITAKLIAESALKRTESLGAH----------RILK--GVIK----------------------------------------------------------------------------------------------------
24 PsiBlast_PDB 90.6533% -80 - C5 -1KNP NADB_ECOLI A:[11-517] --------------------------------------------------------------------------------------------------------------------------------VLIIGSGAAGLSLALRLAD-Q--HQVIVLS-KGPVTEGSTFYAQGGIAAVF-----D--E-------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQ-P-N----------------------GEES---------------------YHLTREGGHS-------H--------RRIL-H-AA---------DATG-REV--ETTL------------VSKALNHP---N--IRVLERTNAVDLIVSD-------KIGLPGTRR---------VV-GAWVWN-R-NK-ETVETCHAKAVVLATGGASKVYQY------------TTNPDISSGDGIAMAWRAG-CRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDG--------------TRFMPDF---------DE-R------------G-ELAPRDIVARAI-DHEMKRLG-----A--------D--------C--------MFLDISHK--P--ADFIRQHFPMIY------EK-L-LG-L-G--IDLTQ-EP-----------------------VPIVPAAHYTCGGVMVDDHGR----------T---------DVEGLYAIGEVSYTGLHGANLMASNSLLECLVYGWSAAEDITRRMP-------YAHDI-S----T------LP-----P-----WD---ESRVENPDE---------RVVI---------QH---NWHELRLFMW------------DYVGIVRTTKRLERALRRITMLQQEIDE--------------YY--------A--------------H-FRVSNNLLELRNLVQVAELIVRCAMMRKESRGLH----------FTL-----------------------------------------------------------------------------------------------------------
25 PsiBlast_PDB 90.6133% -80 - C5 -1KNR NADB_ECOLI A:[11-517] --------------------------------------------------------------------------------------------------------------------------------VLIIGSGAAGLSLALRLAD-Q--HQVIVLS-KGPVTEGSTFYAQGGIAAVF-----D--E-------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQ-P-N----------------------GEES---------------------YHLTREGGHS-------H--------RRIL-H-AA---------DATG-REV--ETTL------------VSKALNHP---N--IRVLERTNAVDLIVSD-------KIGLPGTRR---------VV-GAWVWN-R-NK-ETVETCHAKAVVLATGGASKVYQY------------TTNPDISSGDGIAMAWRAG-CRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDG--------------TRFMPDF---------DE-R------------G-ELAPRDIVARAI-DHEMKRLG-----A--------D--------C--------MFLDISHK--P--ADFIRQHFPMIY------EK-L-LG-L-G--IDLTQ-EP-----------------------VPIVPAAHYTCGGVMVDDHGR----------T---------DVEGLYAIGEVSYTGLHGANLMASNSLLECLVYGWSAAEDITRRMP-------YAHDI-S----T------LP-----P-----WD---ESRVENPDE---------RVVI---------QH---NWHELRLFMW------------DYVGIVRTTKRLERALRRITMLQQEIDE--------------YY--------A--------------H-FRVSNNLLELRNLVQVAELIVRCAMMRKESRGLH----------FTL-----------------------------------------------------------------------------------------------------------
23 PsiBlast_PDB 87.4433% -94 - C5 -1CHU - NADB_ECOLI A:[11-517] --------------------------------------------------------------------------------------------------------------------------------VLIIGSGAAGLSLALRLAD-Q--HQVIVLS-KGPVTE-------------F-----D--E-------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVL----------------------------------------------------------------------------------------------------------------TTL------------VSKALNHP---N--IRVLERTNAVDLIVSD-------KIGLPGTRR---------VV-GAWVWN-R-NK-ETVETCHAKAVVLATGGASKVYQY------------TTNPDISSGDGIAMAWRAG-CRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDG--------------TRFMPDF---------DE-R------------G-ELAPRDIVARAI-DHEMKRLG-----A--------D--------C--------MFLDISHK--P--ADFIRQHFPMIY------EK-L-LG-L-G--IDLTQ-EP-----------------------VPIVPAAHYTCGGVMVDDHGR----------T---------DVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAEDITRRM----------HDI-S----T------LP-----P-----WD---ESRVENPDE---------RVVI---------QH---NWHELRLFMW------------DYVGIVRTTKRLERALRRITMLQQEIDE--------------YY--------A--------------H-FRVSNNLLELRNLVQVAELIVRCAMMRKESRGLH----------FTL-----------------------------------------------------------------------------------------------------------
3 HHSearch 86.5535% -85 - C5 -1CHU - NADB_ECOLI A:[7-522] ----------------------------------------------------------------------------------------------------------------------------HSCDVLIIGSGAAGLSLALRLAD-Q--H-QVIVLSKGPVTE-------------F-----D--E-------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVL----------------------------------------------------------------------------------------------------------------TTL------------VSKAL--NHP-N--IRVLERTNAVDLIVSDKIGLPGTR-------R---------VV-GAWVWN-RNKE-T-VETCHAKAVVLATGGASKVYQY------------TTNPDISSGDGIAMAWRAG-CRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDG--------------TRFMPDF---------DE-R------------G-ELAPRDIVARAI-DHEMKR-------LGA------D--------C--------MFLDISHK--PADF--IRQHFPMIY------EK-L-LG-L-G--IDLT-QEP-----------------------VPIVPAAHYTCGGVMVDDHGR----------T---------DVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAEDITRRM----------HDI-S----TLPP---WD-----ESRV--ENP--DERVVIQHN---------WHEL---------RL---F-------MW------------DYVGIVRTTKRLERALRRITML-----Q--------------QE--------IDEYYAHF-------RVSNNLL---ELRNLVQVAELIVRCAMMRKESRGLH----------FTLD--YPEL----------------------------------------------------------------------------------------------------
96 Fugue 85.7033% -85 - C5 -1CHU - NADB_ECOLI A:[2-533] -----------------------------------------------------------------------------------------------------------------------NTLPEHSCDVLIIGSGAAGLSLALRLAD-Q--HQVIVLS-KGPVTEFDE---------------------------TDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVL----------------------------------------------------------------------------------------------------------------TTL------------VSKA---LNHPN--IRVLERTNAVDLIV---------S-------DKIGLPGTRRVV-GAWVWNRN-KE-T-VETCHAKAVVLATGGASKVYQY------------TTNPDISSGDGIAMAWRAG-CRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDG--------------TRFMPDF---------DE-R------------G-ELAPRDIVARAI-DHEMKR-------L--------GAD------C--------MFLDISHKPAD--F--IRQHFPMIY------EK-L-LG---L--GIDLTQEP-----------------------VPIVPAAHYTCGGVMVDDHGR----------T---------DVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAEDITRRMH-------DISTL-P----P------WD-----E-----SR---VEN-----P---------DERVVIQHNWHELRL---F-------MW------------DYVGIVRTTKRLERALRRITML-----Q--------------QEIDEYYAHFR--------------V-SNNLL---ELRNLVQVAELIVRCAMMRKESRGLHFTLDYPELLTHSGP--SILSP---------------------------------------------------------------------------------------------------
6 HHSearch 85.2235% -76 - C5 -2E5V NADB_SULTO A:[1-458] -------------------------------------------------------------------------------------------------------------------------------MIYIIGSGIAGLSAGVALRR-A--GKKVTLISKRI-DGGSTPIAKGGVAASV-----G--S-------DDSPELHAQDTIRVGDGLCDVKTVNYVTSEAKNVIETFESWGFEFE---E-D-L------------------------------------------------RL--EGGHT-------K--------RRVL-HRT----------DETG-REI--FNFL------------LKLAR--EE--G--IPIIED-RLVEIRVKD-------G-------K---------VT-GFVTEK---RG----LVEDVDKLVLATGGYSYLYEY------------SSTQSTNIGDGMAIAFKAG-TILADMEFVQFHPTVTSLD-GEVFLLTETLRGEGAQIINENG--------------ERFLFNY---------DK-R------------G-ELAPRDILSRAI-YIEMLK-------G--------H--------K--------VFIDLSKI--E--D--FERKFPVVA------KY-L-AR-H-G--HNYK-V-K-----------------------IPIFPAAHFVDGGIRVNIRGE----------S---------NIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFGINLPRYVDSSWE-------GISTD-D----G------IV-----H-----SV---RISGNKTLS---------LKEI---------RR---I-------NW------------ENVGIIRNEEKLVKAINTYSSS-----T---------------------------------------------------QNEAIISYLTALAAEIRKESRGNH----------FRED--YPYK----------------------------------------------------------------------------------------------------
22 PsiBlast_PDB 84.7434% -76 - C5 -2E5V NADB_SULTO A:[2-450] --------------------------------------------------------------------------------------------------------------------------------IYIIGSGIAGLSAGVALRRAG--KKVTLIS-KRI-DGGSTPIAKGGVAASV-----G--S-------DDSPELHAQDTIRVGDGLCDVKTVNYVTSEAKNVIETFESWGFEFE---E-D-------------------------------------------------LRL--EGGHT-------K--------RRVL-HRT----------DETG-REI--FNFLLKLAREEGIPIIEDRL---V---E--IRVKDGKVTGFVTEKR-------G-------L-------------VEDVD-K--------------LVLATGGYSYLYEY------------SSTQSTNIGDGMAIAFKAG-TILADMEFVQFHPTVTSLDGEVF-LLTETLRGEGAQIINENG--------------ERFLFNY---------DK-R------------G-ELAPRDILSRAI-YIEMLK-------G--------H--------K--------VFIDLSKI--E--D--FERKFPVVA------KY-L-AR-H-G--HNYK--VK-----------------------IPIFPAAHFVDGGIRVNIRGE----------S---------NIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFGINLPRYVDSSWE-------GISTD-D----G------IV-----H-----SV---RISGNKTLS---------LKEI---------RR---I-------NW------------ENVGIIRNEEKLVKAIN----------T--------------YS--------S--------------S-TQNEA---IISY------LTALAAEIRKESRGNH------------------------------------------------------------------------------------------------------------------------
5 HHSearch 84.0230% -70 - C5 -1KF6 FRDA_ECOLI A:[4-542] ----------------------------------------------------------------------------------------------------------------------------FQADLAIVGAGGAGLRAAIAAAQ-ANPNAKIALISKVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTG-FHM--LHTL------------FQTSL--QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMNMM-EG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPG---SGILMTEGCRGEGGILVNKNG--------------YRYLQDY---------GM-GPETPLGEPKNKYM-ELGPRDKVSQAF-WHEWRK-------GNTISTPRGD--------V--------VYLDLRHL--GEKK--LHERLPFIC------EL-AKAY-V-G--VDPV-KEP-----------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----EAAIEA-QAAGVEQRLKD--LVNQ-DGGENWAKI---------RDEM---------GL---A-------ME------------EGCGIYRTPELMQKTIDKLAEL-----Q--------------ER--------FKRVRITDTSSVFN-TDLLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRLDEGCTE-----------------------------------------------------------------------------------------------------
42 PsiBlast_CBE 83.9734% -76 - C5 -2E5V NADB_SULTO B:[2-450] --------------------------------------------------------------------------------------------------------------------------------IYIIGSGIAGLSAGVALRRAG--KKVTLIS-KRI-DGGSTPIAKGGVAASV-----G--S-------DDSPELHAQDTIRVGDGLCDVKTVNYVTSEAKNVIETFESWGFEFE---E-D-------------------------------------------------LRL--EGGHT-------K--------RRVL-HRT----------DETG-REI--FNFLLKLAREEGIPIIEDRL---V---E--IRVKDGKVTGFVTEKR-------G-------L-------------VEDVD-K--------------LVLATGGYSYLYEY------------SSTQSTNIGDGMAIAFKAG-TILADMEFVQFHPTVTSLDGEVF-LLTETLRGEGAQIINENG--------------ERFLFNY---------DK-R------------G-ELAPRDILSRAI-YIEMLK-------G--------H--------K--------VFIDLSKI--E--D--FERKFPVVA------KY-L-AR-H-G--HNYK--VK-----------------------IPIFPAAHFVDGGIRVNIRGE----------S---------NIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFGINLPRYVDSSWE-------GISTD-D----G------IV-----H-----SV---RISGNKTLS---------LKEI---------RR---I-------NW------------ENVGIIRNEEKLVKAIN----------T--------------YS--------S--------------S-TQNEA---IISY------LTALAAEIRKESRGNH------------------------------------------------------------------------------------------------------------------------
1 HHSearch 82.5229% -66 - C5 -2BS2 FRDA_WOLSU A:[4-555] ----------------------------------------------------------------------------------------------------------------------------QYCDSLVIGGGLAGLRAAVATQQ-K--GLSTIVLSLIPVKRSHSAAAQGGMQASL-----G--NSKMSD--GDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWT---R-IHK----------------------GDRMAIINAQKTTITEEDFRHGLIHSRD--FGGTK-------K--------WRTC-YT-A---------DATG-HTM--LFAV------------ANECL--KL--G--VSIQDRKEAIALIHQD-------G-------K---------CY-GAVVRDLV-TG-D-IIAYVAKGTLIATGGYGRIYKN------------TTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFP---SGILLTEGCRGDGGILRDVDG--------------HRFMPDY---------EP-EK-----------K-ELASRDVVSRRM-IEHIRK-------GKGVQSPYGQ--------H--------LWLDISIL--GRKH--IETNLRDVQ------EI-C-EY-FAG--IDPA-EKW-----------------------APVLPMQHYSMGGIRTDYRGE----------A---------KLKGLFSAGEAACWDMHGFNRLGGNSVSEAVVAGMIVGEYFAEHCA-------NTQVDLETKT-LEKFVKGQE-----AYMK--SLVESKGTEDVFKI---------KNRM---------KD---V-------MD------------DNVGIFRDGPHLEKAVKELEEL-----Y--------------KK--------SKNVGIKNKRLHANPE-LEEAY---RVPMMLKVALCVAKGALDRTESRGAH----------NRED--YPKR----------------------------------------------------------------------------------------------------
4 HHSearch 82.2830% -68 - C5 -2WDQ SDHA_ECOLI A:[6-548] ----------------------------------------------------------------------------------------------------------------------------REFDAVVIGAGGAGMRAALQISQ-S--GQTCALLSKVFPTRSHTVSAQGGITVAL-----G--NTH-----EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFS---R-LDD----------------------GRIY---------------------QRP--FGGQSKNFGGEQA--------ARTA-AA-A---------DRTG-HAL--LHTL------------YQQNL--KN--H--TTIFSEWYALDLVKNQD------G-------A---------VV-GCTALCIE-TG-E-VVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGIAGA---GVLVTEGCRGEGGYLLNKHG--------------ERFMERY---------AP-N------------AKDLAGRDVVARSI-MIEIRE-------G--------RGCDGPWGPH--------AKLKLDHL--GKEV--LESRLPGIL------EL-S-RTFA-H--VDPV-KEP-----------------------IPVIPTCHYMMGGIPTKVTGQALTVNEKGEDV---------VVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIA-------EQGAL-RDASES------DVEASLDRLNR--WNNN-RNGEDPVAI---------RKAL---------QE---C-------MQ------------HNFSVFREGDAMAKGLEQLKVI-----R--------------ER--------LKNARLDDTSSEFN-TQRVECL---ELDNLMETAYATAVSANFRTESRGAH----------SRFD--FPDR----------------------------------------------------------------------------------------------------
30 PsiBlast_PDB 81.4729% -65 - C5 -3P4S FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
27 PsiBlast_PDB 81.1829% -62 - C5 -3P4R FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
32 PsiBlast_PDB 81.0729% -60 - C5 -1KF6 FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
97 Fugue 81.0428% -67 - C5 -1E7P FRDA_WOLSU A:[1-655] -------------------------------------------------------------------------------------------------------------------------MKVQYCDSLVIGGGLAGLRAAVATQQKG--LSTIVLS-LIPVKRSHSAAAQGGMQASLGNSKMS--D-------GDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWT---R-I-HKGDRMAIINAQKTTITEEDFRHGLIH---------------------SRD--FGGTK-------K--------WRTC-YTA----------DATG-HTM--LFAV------------ANEC---L---KLGVSIQDRKEAIALIHQD-------G-------K---------CY-GAVVRD-L-VTGD-IIAYVAKGTLIATGGYGRIYKN------------TTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFPSGI---LLTEGCRGDGGILRDVDG--------------HRFMPDY---------EPEK------------K-ELASRDVVSRRM-IEHIRK-------GKGVQSPYGQ--------H--------LWLDISILGRK--H--IETNLRDVQ------EI-C-EY-F-A--GIDPAEKW-----------------------APVLPMQHYSMGGIRTDYRGE----------A---------KLKGLFSAGEAACWDMHGFNRLGGNSVSEAVVAGMIVGEYFAEHCANTQVDLETKTLE-K----F------VK-----G-----QE---AYMKSLVESKGTEDVFKIKNRM---------KD---V-------MD------------DNVGIFRDGPHLEKAVKELEEL-----YKKSKNVGIKNKRLHAN--------P--------------E-LEEAY---RVPMMLKVALCVAKGALDRTESRGAH----------NRED--YPKRDDINWLNRTLASWPNPEQTLPTLEYEALDVNEMEIAPGYRGYGAKGNYIENPLSVKRQEEIDKIQSELEAAGKDRHAIQEALMPYELPAKYKARNERLGD
34 PsiBlast_PDB 80.9629% -61 - C5 -1L0V FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
31 PsiBlast_PDB 80.8729% -61 - C5 -4KX6 FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
29 PsiBlast_PDB 80.8429% -60 - C5 -3P4Q FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAEGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
26 PsiBlast_PDB 80.7929% -63 - C5 -2B76 FRDA_ECOLI A:[33-536] ---------------------------------------------------------------------------------------------------------------------------------------------------------IALIS-KVYPMRSHTVAAQGGSAAVA-----Q--D-------HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWS---R-RPD----------------------GSVN---------------------VRR--FGGMK-------I--------ERTW-FAA----------DKTGFHML--HTLF------------QTSL---QFP-Q--IQRFDEHFVLDILVDD-------G-------H---------VR-GLVAMN-MMEG-T-LVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGSGI---LMTEGCRGEGGILVNKNG--------------YRYLQDYGMGPETPLGEP-KNKY---------M-ELGPRDKVSQAF-WHEWRK-------G--------N--------TISTPRGDVVYLDLRHLGEK--K--LHERLPFIC------EL-A-KA-Y-VGVDPVKEP-------------------------IPVRPTAHYTMGGIETDQNCE----------T---------RIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAA-------TAGNG-N----E------AA-----I-----EA---QAAGVEQRL---------KDLV---------NQDGGE-------NWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAEL-----QERFKRVRITDTSSVFN--------T--------------D-LLYTI---ELGHGLNVAECMAHSAMARKESRGAH----------QRL-----------------------------------------------------------------------------------------------------------
2 HHSearch 80.7830% -67 - C5 -2H88 SDHA_CHICK A:[17-557] ----------------------------------------------------------------------------------------------------------------------------HEFDAVVVGAGGAGLRAAFGLSE-A--GFNTACVTKLFPTRSHTVAAQGGINAAL-----G--NME-----DDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFS---R-TEE----------------------GKIY---------------------QRA--FGGQS-------LQFGKGGQAHRCC-CV-A---------DRTG-HSL--LHTL------------YGRSL--RY--D--TSYFVEYFALDLLMEN-------G-------E---------CR-GVIALCIE-DG-T-IHRFRAKNTVIATGGYGRTYFS------------CTSAHTSTGDGTAMVTRAG-LPCQDLEFVQFHPTGIYG---AGCLITEGCRGEGGILINSQG--------------ERFMERY---------AP-V------------AKDLASRDVVSRSM-TIEIREGRGCGPEK--------D--------H--------VYLQLHHL--PPQQ--LATRLPGIS------ETAM-IF-A-G--VDVT-KEP-----------------------IPVLPTVHYNMGGIPTNYKGQVITHVNGED-K---------VVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAETCK-------PGEPV-PSI--KPNAGEESVA----NLDKLRFA---DGTIRTSEA---------RLNM---------QK---T-------MQ------------SHAAVFRTGSILQEGCEKLSQI-----Y--------------RD--------LAHLKTFDRGIVWN-TDLVETL---ELQNLMLCALQTIYGAEARKESRGAH----------ARED--YKLR----------------------------------------------------------------------------------------------------
99 Fugue 73.6230% -58 - C5 -1JRX FRDA_SHEFR A:[1-568] ADNLAEFHVQNQECDSCHTPDGELSNDSLTYENTQCVSCHGTLAEVAETTKHEHYNAHASHFPGEVACTSCHSAHEKSMVYCDSCHSFDFNMPYAKKWLRDEPTIAELAKDKSERQAALASAPHDTVDVVVVGSGGAGFSAAISATDSG--AKVILIE-KEPVIGGNAKLAAGGMNAAW-----T--DQQKAKKITDSPELMFEDTMKGGQNINDPALVKVLSSHSKDSVDWMTAMGADLT---------------------------------D---------------------VGM--MGGAS-------V--------NRAHRPTGG---------AGVG-AHV--VQVL------------YDNA---V---KRNIDLRMNTRGIEVLKDD-------K-------G---------TVKGILVKG-M-YK-G-YYWVKADAVILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAG-GALKDMQYIQAHPTLSVKGGV---MVTEAVRGNGAILVNREGKRFVNEITTADKASAAILAQT---------GK-S------------A-YLIFDDSVRKSLSKIDKYI-------G--------L--------G--------VAPTADSL--V--K--LGKMEGIDG------KA-L-TE-T-V--ARYNSLVSSGKDTDFERPNLPRALNEGNYYAIEVTPGVHHTMGGVMIDTKAE----------VMNAKKQ---VIPGLYGAGEV-TGGVHGANRLGGNAISDIITFGRLAGEEAAKYS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------