@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2227: (2016-04-02 )
MKKLEIQGLKKKYNGKWVIKGIDLTINEKECVALIGPNGAGKSTMINMIVQILTQDEGQITLDGESAKLVREKIGFLPQYPEFYGWMSATECLHFMGKLSNMEKTDLKARINEVLLLVGLEESANKKISTYSGGMRQRLGIAQAILHRPELLVLDEPVSALDPIGRREMMLLLDKLKKEITILFSTHILKDAEEICDRIAIIKNGELVADKTVVQLMEEESSPVFDVEFNGNSEAWQTLLLQNKYVEKIEKVGMVYQVYTTNQKAGSEAVLSSLLQIDGEFIRVENRHQSLEEIFMEKVGK
Atome Classification :
(28 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10....----..---..20........30........40........50........60...---------.--------...--------.-------70-----.....--....80.-.......90------......-..100----.-........110........120.-.....----.130.......140.......150.......160.......170.....-.--.--180.........190.......200.......210.......220.......--------------------230.......240.......250.....-------..260.......270.......280.......290.......300---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK
K
L
EIQ
G
L
K
K
KYN
G
----
K
W
---
V
I
K
GI
D
L
T
INEK
E
C
V
A
L
IGPNGA
G
K
S
T
M
I
N
M
I
V
Q
I
L
TQDE
G
Q
I
T
LDG---------
E
--------
S
A
K
--------
L
-------
V
------
R
E
K
IG--FLPQ
Y
P
E
-
F
Y
G
W
M
S
A
T
E
------
C
L
H
F
M
G
-
K
LS------N-M
E
K
T
D
L
K
A
R
I
-
N
E
V
L
L
L
V
GLEES-ANKKI----STYSG
G
M
R
Q
R
L
G
I
A
Q
A
I
LHRP
E
L
L
V
LDEP
V
S
A
LDPI
G
R
R
E
M
M
L
L
L
D
K
L
K
-
K
--
E
--
I
--
T
I
L
F
S
T
H
I
L
K
D
A
E
E
I
C
D
R
I
A
I
I
KNGELV
A
D
K
T
V
V
Q
L
M
E
EESS
P
V
F
D
V
E
F--------------------NGN
S
E
A
W
Q
T
L
L
L
Q
N
K
Y
V
E
K
I
E
KV
G
M
V
Y
Q
-------
V
Y
TTNQKA
G
S
E
A
V
L
S
S
L
L
Q
IDG
E
F
I
R
V
E
N
R
H
Q
S
L
E
E
I
F
M
E
KVGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
HHSearch
95.01
35%
-115
- C1 -
1VPL
2
?
A:
[14-237]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
V
V
V
K
D
L
R
K
R
I
G
K
----
K
E
---
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
---------
K
--------
N
V
V
EE
P
H
----
E
-------
V
------
R
K
L
I
S
--
Y
L
P
E
E
A
G
-
A
Y
R
N
M
Q
G
I
E
------
Y
L
R
F
V
A
-
G
F
Y
------
A
-
S
S
S
S
E
I
E
E
M
V
-
E
R
A
T
E
I
A
G
L
G
E
K
-
I
K
D
R
V
----
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
S
-
Q
E
-
G
--
L
--
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.38
35%
-116
- C1 -
1VPL
2
?
A:
[14-235]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
V
V
V
K
D
L
R
K
R
I
G
K
----
K
E
---
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
KNVV-----
E
--------
E
P
H
--------
E
-------
V
------
R
K
L
I
S
--
Y
L
P
E
E
A
G
-
A
Y
R
N
M
Q
G
I
E
------
Y
L
R
F
V
A
-
G
F
Y
------
A
-
S
S
S
S
E
I
E
E
M
V
-
E
R
A
T
E
I
A
G
L
G
E
K
-
I
K
D
R
V
----
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
S
-
Q
--
E
G-
L
--
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
HHSearch
88.30
31%
-106
- C1 -
2OLJ
4
?
A:
[22-249]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
AKDTN
L
N
-
K
-------
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
-
M
K
V
------
R
K
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
-
G
--
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
86.81
30%
-98
- C1 -
2IT1
-
?
A:
[1-225]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
E
I
K
L
E
N
I
V
K
K
F
G
N
----
F
T
---
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
---------
K
--------
D
V
T
ELP-----
P
-------
K
------
D
R
N
V
G
--
L
V
F
Q
N
W
A
-
L
Y
P
H
M
T
V
Y
K
------
N
I
A
F
P
L
-
E
L
R
------
K
-
A
P
R
E
E
I
D
K
K
V
-
R
E
V
A
K
M
L
H
I
D
K
L
-
L
N
R
Y
P
----
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
-
K
E
L
G
--
I
--
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
85.58
31%
-105
- C1 -
4WBS
1
?
A:
[40-270]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
V
R
N
L
K
K
R
Y
G
S
----
R
T
---
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
---------
K
--------
S
I
S
--------
L
-------
L
P
I
H
K
--
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
-
V
F
R
K
L
S
V
E
E
------
N
I
R
A
V
L
-
E
L
Q
VGDDGK
R
-
L
S
K
D
A
I
A
S
R
T
-
E
A
L
L
D
E
L
Q
I
S
H
L
-
R
E
N
P
A
----
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
--
N
--
I
--
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
I
I
E
N
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
84.82
31%
-100
- C1 -
4WBS
1
?
B:
[40-270]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
V
R
N
L
K
K
R
Y
G
S
----
R
T
---
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
---------
K
--------
S
I
S
--------
L
-------
L
P
I
H
K
--
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
-
V
F
R
K
L
S
V
E
E
------
N
I
R
A
V
L
-
E
L
Q
VGGK--
R
-
L
S
K
D
A
I
A
S
R
T
-
E
A
L
L
D
E
L
Q
I
S
H
L
-
R
E
N
P
A
----
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
--
N
--
I
--
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
I
I
E
N
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
84.59
31%
-111
- C1 -
2OUK
1
?
C:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTNLNK
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
84.29
31%
-112
- C1 -
2OLJ
4
?
A:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTN
L
N
K
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
84.18
30%
-109
- C1 -
4RVC
-
?
A:
[2-218]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
L
E
V
K
D
L
S
G
G
Y
T
A
----
Q
N
---
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
YRLA-----
D
--------
G
P
E
--------
T
-------
Y
------
R
R
Q
F
A
--
Y
I
P
E
T
P
V
-
L
Y
E
E
L
T
L
E
E
------
H
L
R
L
A
A
-
M
A
Y
------
G
-
L
S
E
A
E
Y
E
R
R
L
-
P
P
L
L
R
E
F
R
L
E
R
R
-
L
S
S
F
P
----
A
H
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
K
A
K
--
G
--
A
--
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
84.09
31%
-107
- C1 -
3C4J
3
?
A:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTN
L
N
K
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
83.94
31%
-110
- C1 -
3C4J
4
?
B:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTNLNK
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
83.74
30%
-104
* C1 *
3TUI
1
METN_ECOLI
C:
[23-254]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
GTRT
I
Q
---
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---------
Q
--------
E
L
T
TLSESELT
K
-------
A
------
R
R
Q
I
G
--
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
------
N
V
A
L
P
L
-
E
L
D
------
N
-
T
P
K
D
E
V
K
R
R
V
-
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
----
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
RL
G
--
L
--
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
83.71
30%
-96
- C1 -
4P33
7
LPTB_ECOLI
A:
[3-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
K
A
Y
K
G
----
R
R
---
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---------
D
--------
D
I
S
--------
L
-------
L
P
L
H
A
R
A
R
R
G
I
G
--
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
--
V
L
Q
I
R
D
-
D
L
S
------
A
-
E
Q
R
E
D
---
R
A
-
N
E
L
M
E
E
F
H
I
E
H
L
-
R
D
S
M
G
----
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
--
S
G-
L
--
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
Fugue
83.69
24%
-76
- C1 -
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
LPTGQNYT
K
T
D
F
E
H
D
V
M
N
V
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
L
R
R
E
F
V
K
S
I
L
R
QE
I
S
W
F
D
T
N
HSGT
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
GD
K
I
G
M
A
F
Q
Y
L
S
Q
F
I
T
G
F
I
V
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
T
F
A
I
R
E
T
L
R
Y
A
K
A
G
K
V
V
E
E
T
I
S
S
I
R
T
V
V
S
L
NG
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
V
L
K
G
L
F
L
G
I
S
F
G
A
M
Q
A
S
N
F
I
S
F
A
L
A
F
Y
I
G
V
G
W
V
H
D
GSLN
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
T
A
Q
G
A
A
S
G
I
Y
E
V
LDRKPVIDSS
S
K
A
G
R
KDMKI
K
G
D
I
T
V
E
N
V
H
F
T
Y
P
S
----
R
P
DVP
I
L
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
D
V
L
K
G
K
I
T
I
D
G
---------
V
DVRDI---
N
L
E
--------
F
-------
L
------
R
K
N
V
A
--
V
V
S
Q
E
P
A
-
L
F
N
-
C
T
I
E
E
------
N
I
S
L
G
K
-
E
G
I
------
T
-
R
E
E
M
V
A
A
C
K
M
A
N
A
E
K
F
I
K
T
L
P
N
G
-
Y
N
T
L
V
GDR
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
S
E
G
I
V
Q
Q
A
L
D
K
A
A
-
K
--
G
--
R
--
T
T
I
I
I
A
H
R
L
S
T
I
R
N
A
-
D
L
I
I
S
C
K
N
G
Q
V
V
E
V
G
D
H
R
A
L
M
A
Q
Q
G
---------------------------------
L
Y
Y
D
L
V
T
A
Q
T
F
T
D
A
V
D
S
A
A
------------------
E
G
E
R
I
G
K
D
A
L
S
R
L
K
Q
E
L
E
E
N
N
A
Q
K
T
N
L
F
E
I
L
Y
H
A
R
P
H
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
E
A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
72
HHSearch
83.38
29%
-109
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
I
L
K
V
E
E
L
N
Y
N
Y
S
D
G---
T
H
---
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
L
F
D
N
---------
K
--------
P
I
D
YS
R
K
G
I
M
-
K
-------
L
------
R
E
S
I
G
--
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
Y
Q
------
D
V
S
F
G
A
-
V
N
M
------
K
-
L
P
E
D
E
I
R
K
R
V
-
D
N
A
L
K
R
T
G
I
E
H
L
-
K
D
K
P
T
----
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
V
E
M
Q
-
K
E
L
G
--
I
--
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
E
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
83.30
31%
-106
- C1 -
2OLK
1
?
D:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTNLNK
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
83.27
31%
-113
- C1 -
2OLK
1
?
C:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTNLNK
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
83.14
25%
-88
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
GTRT
I
Q
---
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---------
Q
ELTTLSES
E
L
T
--------
K
-------
A
------
R
R
Q
I
G
--
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
------
N
V
A
L
P
L
-
E
L
D
------
N
-
T
P
K
D
E
V
K
R
R
V
-
T
E
L
L
S
L
V
G
L
G
D
K
-
H
D
S
Y
P
----
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
--
R
LG
L
--
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
QSTLHLDIPEDYQERLQAEP
F
T
D
C
V
P
M
L
R
L
E
F
T
G
Q
S
V
D
A
P
L
L
S
E
T
A
R
R
FNVNNNI
I
S
A
Q
M
D
Y
A
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
I
A
W
L
Q
E
H
H
V
K
V
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.13
30%
-91
- C1 -
4QC2
2
?
A:
[2-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
G
----
R
R
---
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---------
D
--------
D
I
S
--------
L
-------
L
P
L
H
A
R
A
R
R
G
I
G
--
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
--
V
L
Q
I
R
D
-
D
L
S
------
A
-
E
Q
R
E
D
---
R
A
-
N
E
L
M
E
E
F
H
I
E
H
L
-
R
D
S
M
G
----
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
--
S
G-
L
--
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
83.09
31%
-115
- C1 -
2OUK
1
?
A:
[22-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTN
L
N
K
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
82.90
31%
-108
- C1 -
3C41
3
?
J:
[1-217]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
----
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------
I
--------
N
L
K
--------
A
KDTNLNK
V
------
R
E
E
V
G
--
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
------
N
I
T
L
A
P
M
K
V
R
------
K
-
W
P
R
E
K
A
E
A
K
A
-
M
E
L
L
D
K
V
G
L
K
D
K
-
A
H
A
Y
P
----
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
82.72
31%
-115
- C1 -
4YMU
2
?
A:
[4-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
D
V
Y
K
N
F
G
S
----
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
VKI------
N
--------
N
G
K
--------
V
N
I
N
K
---
V
------
R
Q
K
V
G
--
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
------
N
I
T
L
A
P
V
K
V
K
------
K
-
M
N
K
K
E
A
E
E
L
A
-
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
P
----
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
--
E
G-
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
81.84
30%
-101
- C1 -
4P32
2
LPTB_ECOLI
A:
[3-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
K
A
Y
K
G
----
R
R
---
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---------
D
--------
D
I
S
--------
L
-------
L
P
L
H
A
R
A
R
R
G
I
G
--
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
--
V
L
Q
I
R
D
-
D
L
S
------
A
-
E
Q
R
E
D
---
R
A
-
N
E
L
M
E
E
F
H
I
E
H
L
-
R
D
S
M
G
----
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
--
S
G-
L
--
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
76.61
33%
-114
- C1 -
1L2T
4
Y796_METJA
B:
[19-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKTNDLDDD
E
--------
L
T
K
--------
I
-------
R
------
R
D
K
I
G
--
F
V
F
Q
Q
F
N
-
L
I
P
L
L
T
A
L
E
NVELPL
I
F
K
Y
R
G
-
A
M
S
------
G
-
E
E
R
---
R
K
R
A
-
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
----
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
--
E
--
D
GK
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
76.59
33%
-110
- C1 -
1L2T
4
Y796_METJA
A:
[19-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKTNDLD
D
D
E
--------
L
T
K
--------
I
-------
R
------
R
D
K
I
G
--
F
V
F
Q
Q
F
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
PL
I
F
K
Y
R
G
-
A
M
S
------
G
-
E
E
R
---
R
K
R
A
-
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
----
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
--
E
--
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
76.24
33%
-115
- C1 -
3TIF
6
Y796_METJA
B:
[19-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKTNDLDDD
E
--------
L
T
K
--------
I
-------
R
------
R
D
K
I
G
--
F
V
F
Q
Q
F
N
-
L
I
P
L
L
T
A
L
E
NVELPL
I
F
K
Y
R
G
-
A
M
S
------
G
-
E
E
R
---
R
K
R
A
-
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
----
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
--
E
--
D
GK
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
74.69
33%
-112
- C1 -
3TIF
7
Y796_METJA
A:
[19-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKTNDLD
D
D
E
--------
L
T
K
--------
I
-------
R
------
R
D
K
I
G
--
F
V
F
Q
Q
F
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
PL
I
F
K
Y
R
G
-
A
M
S
------
G
-
E
E
R
---
R
K
R
A
-
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
----
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
--
E
--
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.11
30%
-6
- C1 -
4P31
2
LPTB_ECOLI
A:
[3-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
K
A
Y
K
G
----
R
R
---
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---------
D
--------
D
I
S
--------
L
-------
L
P
L
H
A
R
A
R
R
G
I
G
--
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
--
V
L
Q
I
R
D
-
D
L
S
------
A
-
E
Q
R
E
D
---
R
A
-
N
E
L
M
E
E
F
H
I
E
H
L
-
R
D
S
M
G
----
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
--
S
G-
L
--
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------