@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2335: (2016-04-02 )
MRITDLLSKDVMIMSLQATTKEAAIDEMIASLKSNGKINDEVLFKKAIMNREAQSSTGVGEGIAMPHAKTKAVNEPTVVFAKSEKGLDYDALDGQPAHLFFMIAAPDGANATHLETLAALSRLLVHPAFVQSLRDAKTPEEVINLFNNEQEDSEETVVAPTSTNDTGKSVVAVTACPTGIAHTYMAAEKLQETANKLGVRIKVETNGSRGVENRLTDKEIAEADGVIIAADVQVDMPRFDGKHLIAKPVAAGIHKPEELIKEAISGNAPIYKAEEGSQATESADGLSIGQQIYKHLMSGVSHMLPFVIGGGIAIAIAFMLDQMLGVPQDQLAKLGSYNEIPALLKQIGDVAFGFMLPVFAGYIAYSISDRPGLVAGFVAGGVASVGGAGFLGALVGGFLAGYAVELIKLALKKLPKTLDGIKVVLFYPVLSVLIVGLLMLLLNVPMSALNTWLNDFLNSLSGTNAVILGLLLGAMMAADLGGPINKAAYIFATGTLAASVATGGSAIMAATMAAGMVPPLATFVATLIFRNKFTAQERDAGLTNSILGASFITEGAIPFAAADPLRMIPSFIAGSAITGAIVMFLNIKVLAPHGGVFVIFLVSQPWFYIIAIIIGTLISAGLIGVLRKKPTV
Atome Classification :
(20 SA)
---------------------.........10..-......20........30.-....-...--40.....------------...50-...-.----------.---..----.60----------------------.-----------.....---------..-70---.-..---....-.80........90-........100...--....110..-.....120.......130.......140........150.......160.......170.......180.......190..--.....200.......210.......220.......230..-.....240.......250.......260.......270.......280.......290.......300.......310....-...320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430...-.-...440.-......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.-......580.......590.......600.......610.......620.......630
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------M
R
I
T
D
L
LSKD
V
M
I
-
M
S
L
QAT
T
K
E
A
A
I
D
E
M
I
A
S
L
-KSNG-KI
N
--
D
E
V
L
F
K
K
------------
A
I
MNR-EAQ-S----------S---TG----VGE----------------------G-----------IAMPH---------AK-TK---A-VN---EP
T
V
-
V
F
A
KSEKGLDYDA-LDGQP
A
H
L
F
F
M
I
AA--PDGAN
A
T
H
L
-
E
T
L
A
A
L
S
R
L
LV
H
P
A
F
V
Q
S
L
RDAK
T
P
E
E
-
V
I
N
L
FNNEQEDSEE
T
V
V
APTSTNDTG
K
S
V
V
A
V
TACPT
G
I
A
H
T
Y
M
A
A
E
K
L
Q
E
T
A
--
N
KL
G
V
R
I
K
V
ETNGSRGVENRLT
D
K
E
IAEAD
G
V
I
I
A
A
D
V
Q
V-DMPRFDGK
H
L
I
A
K
P
V
A
AGIH
K
P
E
E
L
I
K
E
A
ISGNA
P
I
Y
KAEEGSQATESADG
L
S
I
G
Q
Q
I
Y
K
H
L
M
S
G
V
S
H
M
L
P
F
V
IG
G
G
I
A
I
A
I
-
A
F
M
L
D
Q
M
LGV
P
Q
D
Q
L
A
KLGSY
N
E
I
P
A
L
L
K
Q
I
G
D
V
A
F
G
F
M
L
P
V
F
A
G
Y
I
A
Y
SISDRP
G
L
V
A
G
F
V
AG
G
V
A
SVGG
A
G
F
L
G
A
L
V
G
G
F
L
A
G
Y
A
V
E
L
I
K
L
A
L
K
K
L
P
K
TLDG
I
K
V
V
L
F
Y
P
V
L
S
V
L
I
V
-
G
-
L
L
M
L
L
L
N-V
P
M
S
A
L
N
T
W
L
N
D
F
L
N
SLSG
T
N
A
V
I
L
G
L
L
L
G
A
M
M
A
A
DLGGPIN
K
A
A
Y
I
F
ATG
T
L
A
A
SVATG
G
S
A
I
M
A
A
T
M
AAGMV
P
P
L
A
T
F
V
A
T
L
I
FRNKFT
A
Q
E
RDAGL
T
N
S
I
L
G
A
S
F
ITEGAIPFAAA
D
P
L
R
M
I
P
S
F
IA-
G
S
A
I
T
G
A
I
V
M
F
L
N
I
K
V
LAPHG
G
V
F
V
I
F
L
VSQ
P
W
F
Y
I
I
A
I
I
I
G
T
L
I
S
A
G
L
I
G
V
LRKKPTV
5
PsiBlast_PDB
68.56
26%
-85
- C5 -
2A0J
-
?
A:
[4-147]
-----------------------
I
G
E
I
L
P
L
S
H
I
V
-
L
D
M
E
V
G
S
K
K
R
L
F
E
E
A
G
L
L
L
-
E
R
E
S
-
S
L
S
--
H
A
D
V
F
E
-------------
C
L
F
A
R
-
E
K
L
-
G
----------
S
---
T
G
----
L
G
Q
----------------------
G
-----------
V
A
I
P
H
---------
G
R
-
H
A
---
G
-
V
K
---
Q
A
T
G
-
A
F
I
R
T
R
E
P
V
G
F
D
A
-
P
D
G
K
P
V
S
L
I
F
I
L
L
V
--
P
E
N
A
T
G
E
H
L
-
E
V
L
S
K
L
A
G
K
F
S
Q
K
S
I
R
E
S
L
M
T
V
S
S
A
E
E
-
V
R
A
I
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
67.23
29%
-81
- C5 -
1A6J
1
PTSN_ECOLI
A:
[8-157]
---------------------
L
Q
L
S
S
V
L
N
R
E
C
T
R
-
S
R
V
H
C
Q
S
K
K
R
A
L
-
E
I
I
S
E
L
-
A
A
K
Q
L
S
L
P
--
P
Q
V
V
F
E
-------------
A
I
L
T
R
-
E
K
M
-
G
----------
S
---
T
G
----
I
G
N
----------------------
G
-----------
I
A
I
P
H
---------
G
K
-
L
E
---
E
-
D
T
---
L
R
A
V
G
V
F
V
Q
L
E
T
P
I
A
F
D
A
-
I
D
N
Q
P
V
D
L
L
F
A
L
L
V
--
P
A
D
Q
T
K
T
H
L
-
H
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
-
L
Y
Q
I
I
T
D
T
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
66.94
26%
-77
* C5 *
1A6J
1
PTSN_ECOLI
A:
[8-157]
---------------------
L
Q
L
S
S
V
L
N
R
E
C
T
R
-
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
-
A
K
Q
L
-
S
L
---
P
P
Q
V
V
F
E
------------
A
I
L
T
R
-
E
K
M
-
G
----------
S
---
T
G
----
I
G
N
----------------------
G
-----------
I
A
I
P
H
---------
G
K
L
E
E
---
D
-
T
L
---
R
A
V
G
-
V
F
V
Q
L
E
T
P
I
A
F
D
A
-
I
D
N
Q
P
V
D
L
L
F
A
L
L
V
--
P
A
D
Q
T
K
T
H
L
-
H
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
-
L
Y
Q
I
I
T
D
T
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
66.71
31%
-85
- C5 -
3OXP
1
?
A:
[5-149]
-----------------------
L
K
T
L
L
T
S
D
V
I
Q
-
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
-
I
D
N
G
-
A
V
E
----
A
R
Y
V
E
------------
A
I
Y
R
S
H
E
A
I
-
G
----------
P
---
Y
Y
V---
V
G
P
----------------------
G
-----------
I
A
M
P
H
---------
A
R
-
P
E
D--
G
-
V
N
---
R
L
S
L
-
A
L
T
V
I
T
E
G
V
T
F
N
A
-
E
G
N
D
P
V
K
L
L
I
V
L
A
A
--
T
D
S
--
N
S
H
I
-
E
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
-
I
L
S
V
I
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
66.71
25%
-79
- C5 -
2A0J
-
?
A:
[3-147]
----------------------
L
I
G
E
I
L
P
L
S
H
I
V
-
L
D
M
E
V
G
S
K
K
R
L
F
E
E
A
G
L
L
L
-
E
R
E
S
-
S
L
S
---
H
A
D
V
F
E
------------
C
L
F
A
R
-
E
K
L
-
G
----------
S
---
T
G
----
L
G
Q
----------------------
G
-----------
V
A
I
P
H
---------
G
R
-
H
A
---
G
-
V
K
---
Q
A
T
G
-
A
F
I
R
T
R
E
P
V
G
F
D
A
-
P
D
G
K
P
V
S
L
I
F
I
L
L
V
--
P
E
N
A
T
G
E
H
L
-
E
V
L
S
K
L
A
G
K
F
S
Q
K
S
I
R
E
S
L
M
T
V
S
S
A
E
E
-
V
R
A
I
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
66.35
26%
-74
- C5 -
1A6J
1
PTSN_ECOLI
A:
[9-157]
----------------------
Q
L
S
S
V
L
N
R
E
C
T
R
-
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
-
A
K
Q
L
-
S
L
---
P
P
Q
V
V
F
E
------------
A
I
L
T
R
-
E
K
M
-
G
----------
S
---
T
G
----
I
G
N
----------------------
G
-----------
I
A
I
P
H
---------
G
K
-
L
E
E--
D
-
T
L
---
R
A
V
G
-
V
F
V
Q
L
E
T
P
I
A
F
D
A
-
I
D
N
Q
P
V
D
L
L
F
A
L
L
V
--
P
A
D
Q
T
K
T
H
L
-
H
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
-
L
Y
Q
I
I
T
D
T
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
65.57
26%
-79
- C5 -
3URR
4
?
A:
[5-152]
----------------------
R
L
A
K
I
L
P
L
E
N
V
V
-
I
G
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
-
E
N
Q
N
-
G
I
---
A
R
S
T
V
T
D
------------
N
L
F
A
R
-
E
R
L
-
G
----------
S
---
T
G
----
L
G
E
----------------------
G
-----------
V
A
I
P
H
---------
G
R
-
I
K
---
G
-
L
K
---
H
P
L
A
-
A
F
V
R
L
A
E
P
I
P
F
E
A
-
P
D
G
Q
P
V
S
L
L
I
F
L
L
V
--
P
E
Q
A
T
Q
A
H
L
-
E
I
L
S
E
I
A
Q
L
L
S
D
R
D
T
R
E
R
L
H
T
E
P
D
R
D
E
-
L
H
R
L
L
T
Q
W
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
64.31
29%
-85
- C5 -
3OXP
1
?
A:
[8-147]
--------------------------
L
L
T
S
D
V
I
Q
-
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
-
I
D
N
G
-
A
V
----
E
A
R
Y
V
E
------------
A
I
Y
---
R
S
H
-
E
----------
A
---
I
G
PYYV
V
G
P
----------------------
G
-----------
I
A
M
P
H
---------
A
R
-
P
E
D--
G
-
V
N
---
R
L
S
L
-
A
L
T
V
I
T
E
G
V
T
F
N
A
-
E
G
N
D
P
V
K
L
L
I
V
L
A
A
--
T
D
--
S
N
S
H
I
-
E
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
-
I
L
S
V
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
63.27
26%
-68
- C5 -
1J6T
-
A:
[7-144]
---------------------------
L
G
A
E
N
I
F
-
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
-
V
K
G
G
-
Y
V
E
--
P
E
--
Y
V
Q
------------
A
M
L
D
R
-
E
K
L
-
T
----------
P
---
T
Y
----
L
G
E
----------------------
S
-----------
I
A
V
P
H
---------
G
T
-
V
E
---
A
-
K
D
RVL
K
T
G
V
-
V
F
C
Q
Y
P
E
G
V
R
F
G
E
-
E
E
D
D
I
A
R
L
V
I
G
I
A
A
-----
R
N
N
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
-
V
L
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
62.95
15%
-59
- C5 -
1HYN
-
B3AT_HUMAN
P:
[109-318]
----------------------
E
L
R
R
V
F
T
K
G
T
V
L
-
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
-
I
F
E
D
-
Q
I
R
PQ
D
R
E
E
L
L
R
------------
A
L
L
L
K
-
H
S
H
-
A
GELEALGGVK
P
AVL
T
R
----
S
G
D
PSQPLLPQHSSLETQLFCEQGD
G
GTEGHSPSGIL
E
K
I
P
P
DSEATLVLV
G
R
-
A
D
---
F
-
L
E
---
Q
P
V
L
-
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
E
L
P
V
P
I
R
F
L
F
V
L
L
G
--
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
-
L
L
H
S
L
E
G
F
L
D
C
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
62.61
26%
-72
- C5 -
1A3A
-
PTM3C_ECOLI
A:
[7-144]
---------------------------
L
G
A
E
N
I
F
-
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
-
V
K
G
G
-
Y
V
E
--
P
E
--
Y
V
Q
------------
A
M
L
D
R
-
E
K
L
-
T
----------
P
---
T
Y
----
L
G
E
----------------------
S
-----------
I
A
V
P
H
---------
G
T
-
V
E
---
A
-
K
D
RVL
K
T
G
V
-
V
F
C
Q
Y
P
E
G
V
R
F
G
E
-
E
E
D
D
I
A
R
L
V
I
G
I
A
A
-----
R
N
N
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
-
V
L
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
62.00
23%
-77
- C5 -
2OQ3
-
PTMA_ECOLI
A:
[1-146]
---------------------
M
R
L
S
D
Y
F
P
E
S
S
I
S
-
V
I
H
S
A
K
D
W
Q
E
A
I
D
F
S
M
V
S
L
-
L
D
K
N
-
Y
I
S
----
E
N
Y
I
Q
------------
A
I
K
D
S
-
T
I
N
N
G
----------
P
Y--
Y
I
----
L
A
P
----------------------
G
-----------
V
A
M
P
H
---------
A
R
-
P
E
---
C
G
A
L
---
K
T
G
M
-
S
L
T
L
L
E
Q
G
V
Y
F
P
G
-
N
D
-
E
P
I
K
L
L
I
G
L
S
A
--
A
D
--
A
D
S
H
I
-
G
A
I
Q
A
L
S
E
L
L
C
E
E
E
I
L
E
Q
L
L
T
A
S
S
E
K
Q
-
L
A
D
I
I
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
61.23
26%
-63
- C5 -
1A3A
-
PTM3C_ECOLI
A:
[4-147]
------------------------
L
F
K
L
G
A
E
N
I
F
-
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
-
V
K
G
G
-
Y
V
E
----
P
E
Y
V
Q
------------
A
M
L
D
R
-
E
K
L
-
T
----------
P
---
T
Y
----
L
G
E
----------------------
S
-----------
I
A
V
P
H
---------
G
T
-
V
E
AKD
R
-
V
L
---
K
T
G
V
-
V
F
C
Q
Y
P
E
G
V
R
F
G
E
-
E
E
D
D
I
A
R
L
V
I
G
I
A
A
--
R
N
---
N
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
-
V
L
E
L
L
A
G
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
60.97
25%
-67
- C5 -
2FEW
-
A:
[7-144]
---------------------------
L
G
A
E
N
I
F
-
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
-
V
K
G
G
-
Y
V
E
--
P
E
--
Y
V
Q
------------
A
M
L
D
R
-
E
K
L
-
T
----------
P
---
T
Y
----
L
G
E
----------------------
S
-----------
I
A
V
P
Q
---------
G
T
-
V
E
---
A
-
K
D
RVL
K
T
G
V
-
V
F
C
Q
Y
P
E
G
V
R
F
G
E
-
E
E
D
D
I
A
R
L
V
I
G
I
A
A
-----
R
N
N
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
-
V
L
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
59.83
19%
-79
- C5 -
3BJV
-
?
A:
[1-151]
---------------------
M
N
L
A
Q
A
F
K
E
N
H
S
I
R
L
G
L
T
A
K
D
W
K
E
A
V
K
L
S
V
T
P
L
-
I
E
S
G
-
A
V
K
----
P
E
Y
Y
N
------------
A
I
I
E
S
T
E
S
Y
-
G
----------
P
---
Y
Y
I---
L
M
P
----------------------
G
-----------
M
A
M
P
H
---------
A
R
-
P
E
A--
G
-
V
Q
---
R
D
A
F
-
S
L
V
T
L
T
E
P
V
T
F
T
D
-
G
--
K
E
V
Q
V
L
L
A
L
A
A
--
T
S
S
--
K
I
H
T
S
V
A
I
P
Q
I
I
A
L
F
E
L
D
H
S
I
E
R
L
V
N
C
K
T
P
E
E
-
V
L
A
M
V
E
E
S
K
S
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
59.66
27%
-59
- C5 -
3URR
3
?
A:
[5-126]
----------------------
R
L
A
K
I
L
P
L
E
N
V
V
-
I
G
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
-
E
N
Q
N
-
G
I
A
--
R
S
T
V
-
T
D
------------
N
L
F
A
R
-
E
R
L
-
G
----------
S
---
T
G
----
L
G
E
----------------------
G
-----------
V
A
I
P
H
---------
G
R
-
I
K
---
G
-
L
K
---
H
P
L
A
-
A
F
V
R
L
A
E
P
I
P
F
E
A
-
P
D
G
Q
P
V
S
L
L
I
F
L
L
V
--
P
E
Q
A
T
Q
A
H
L
-
E
I
L
S
E
I
A
Q
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
59.59
47%
-38
- C5 -
2M1Z
-
?
A:
[2-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
K
I
I
A
V
T
A
C
A
T
G
V
A
H
T
Y
M
A
A
Q
A
L
K
K
G
A
--
K
K
M
G
N
L
I
K
V
E
T
Q
G
A
T
G
I
E
N
E
L
T
E
K
D
V
N
I
G
E
V
V
I
F
A
V
D
T
K
V
R
N
K
E
R
F
D
G
K
V
V
L
E
V
P
V
S
A
P
I
K
D
A
E
K
V
I
N
A
A
L
A
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
59.21
47%
-43
- C5 -
2M1Z
-
?
A:
[3-101]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
I
I
A
V
T
A
C
A
T
G
V
A
H
T
Y
M
A
A
Q
A
L
K
K
G
A
--
K
K
M
G
N
L
I
K
V
E
T
Q
G
A
T
G
I
E
N
E
L
T
E
K
D
V
N
I
G
E
V
V
I
F
A
V
D
T
K
V
R
N
K
E
R
F
D
G
K
V
V
L
E
V
P
V
S
A
P
I
K
D
A
E
K
V
I
N
A
A
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
58.87
20%
-74
- C1 -
4R4X
2
?
A:
[1-546]
A
Q
T
Y
E
I
T
Y
Q
N
S
F
EGKINQN
H
I
I
S
I
T
N
--
S
D
K
T
L
L
-
F
N
E
K
I
K
N
K
K
A
D
F
P
F
E
V
N
E
I
N
R
K
N
N
-
E
V
S
--
Q
F
A
F
L
N
N
N
E
I
V
K
T
S
D
NTIL
A
K
Q
E
F
-
K
P
T
-
S
----------
E
---
T
G
----
K
I
L
----------------------
G
-----------
Y
N
V
K
K
---------
A
V
-
T
S
---
V
-
N
S
---
N
T
I
E
-
V
W
Y
T
N
D
L
K
V
K
G
G
P
S
I
L
G
Q
D
L
G
L
V
L
K
T
V
R
NG
S
S
V
V
E
A
T
S
V
-
K
K
I
K
A
L
D
D
Q
S
L
F
N
G
K
N
I
T
E
K
D
A
L
T
Y
K
D
M
I
-----
W
K
S
R
F
I
T
I
P
V
F
E
N
E
T
I
N
F
S
D
A
S
K
S
D
Q
V
I
Q
R
F
G
N
G
T
I
I
L
K
K
V
K
I
P
E
I
K
QG
N
T
I
F
V
E
L
K
Q
K
S
N
G
---------
D
A
Y
D
R
T
G
D
V
F
I
I
P
Q
E
R
A
I
--------------
S
Y
Y
T
G
L
T
Q
G
V
K
S
L
P
V
Y
Q
N
G
N
G
K
S
Y
Q
------------
G
V
A
L
T
-----------
P
D
Y
L
P
F
-------
I
E
L
M
R
F
F
------
T
P
F
G
----
I
G
H
F
N
E
K
I
Q
L
K
--------
G
K
N
W
H
N
N
T
P
Y
R
Q
D
I
T
E
L
R
P
Q
L
S
-----------
G
K
E
I
L
I
G
A
F
I
G
N
Y
D
K
G
G
H
Q
I
S
L
E
L
S
I
H
P
D
Q
Q
K
I
V
N
N
N
F
V
L
--
P
V
F
N
T
T
N
V
M
E
M
A
G
Q
D
Y
P
T
M
F
N
S
D
K
G
V
E
V
D
F
I
L
T
K
D
L
K
N
A
Q
L
R
Y
I
T
T
G
H
G
G
W
G
A
G
D
E
F
V
P
--
K
E
N
S
I
Y
L
D
G
K
L
A
H
A
F
-----------------
T
P
W
R
T
D
C
G
S
Y
R
L
F
N
P
A
S
G
N
F
E
D
-
G
L
S
S
S
D
L
S
R
S
N
W
C
P
G
T
I
T
N
---------
P
V
Y
I
N
L
G
N
L
N
A
G
K
H
T
I
Q
V
K
I
P
Q
G
A
P
E
G
S
-------
S
Q
S
F
W
N
V
S
G
V
L
L
G
Q
E
H
H
-------
H
H
H
H
H
H
7
PsiBlast_PDB
58.82
27%
-60
- C5 -
4GQX
-
?
A:
[15-136]
----------------------
R
L
A
K
I
L
P
L
E
N
V
V
-
I
D
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
-
E
N
Q
N
-
G
I
A
--
R
S
T
V
-
T
D
------------
N
L
F
A
R
-
E
R
L
-
G
----------
S
---
T
G
----
L
G
E
----------------------
G
-----------
V
A
I
P
H
---------
G
R
-
I
K
---
G
-
L
K
---
H
P
L
A
-
A
F
V
R
L
A
E
P
I
P
F
E
A
-
P
D
G
Q
P
V
S
L
L
I
F
L
L
V
--
P
E
Q
A
T
Q
A
H
L
-
E
I
L
S
E
I
A
Q
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------