@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2421: (2016-04-03 )
LKSKLELLFTKISHVMNVWQATFFAAVSWVLALITIQTIYLWSISIRDDSLFLREVSQAIVQLFGTNKYTRIMQSFWMMSLKFLIIFLIACLFFAFFYRLMRQRILKKQLRTINFALNDGKPVDTESFVPEIQELERNIENMRERQKKLMQQEEQAQQARNDLITNVSHDLRTPLTSILGYLSYIHEDRYRDEIELRYYTELVYGKARHLHKLIDDLFSYTRLDSVDYQLKKDELDIVELLRQLVAEYDGRAAERNMQIVEHFDANKLIIGGDGNQIMRLFENLFSNALRYGEGNKQIDVSAKKEDNMAVVRVTNYGEEIPNVDLPYLFERFYKVDKNRTTTGTGLGLAIAKSIVEKHGGIVTAESKKRQTSFIVKLPLI
Atome Classification :
(21 SA)
--------.........10........20........30........40........50........60........70........80........90........100----.........110.......120.......130.......140.......150.......160.......170......-.180.......190........200.......210.......220.......230.......240-........-----250--.........260...-.-...270--.......280.......290.---...---...300.--......310.......320.......330....--...340.........350.......360...-.-.-.-.-370.-.......380
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------LK
S
K
L
E
L
L
F
T
K
I
S
H
V
M
N
V
W
Q
A
T
F
F
A
A
V
S
W
V
L
A
L
I
T
I
Q
T
I
Y
L
W
S
I
S
IRD
D
S
L
F
L
R
E
V
S
Q
A
I
V
Q
L
FGT
N
K
Y
T
R
I
M
Q
S
F
W
M
M
S
L
K
F
L
I
I
F
L
I
A
C
L
F
F
A
F
F
Y
R
L
------
M
R
Q
R
I
L
K
K
Q
L
R
T
I
N
F
ALNDGKPV
D
T
E
S
F
V
P
E
I
Q
E
L
E
R
N
I
E
N
M
R
E
R
Q
K
K
L
M
Q
Q
E
E
Q
A
Q
Q
A
R
N
D
L
I
T
NV
S
H
D
L
R
T
P
L
T
S
I
-
L
G
Y
L
S
Y
I
H
E
D
RYR-
D
E
I
E
L
R
Y
Y
T
E
L
V
YG
K
A
R
H
L
H
K
L
I
D
D
L
F
S
Y
TRLDSV
D
Y
Q
LKKDE
L
D
I
V
E
L
L
--
R
Q
L
V
A
EYD-----G----RAAERN
M
Q
I
V
E
HFDA-
N
-
K
L
I
IGG--D
G
N
Q
I
M
R
L
F
E
N
L
F
S
N
A
L
RYGE---GN
K
---
Q
I
D
V
S
AK--KED
N
M
A
V
V
R
VTNYGEEIPNV
D
L
P
Y
L
F
E
R
F
Y
K
VD--KNRT--TTGT
G
L
G
L
A
I
A
K
S
I
V
E
KHG
G
I
V
TAE-S-K-K-R-
Q
-
T
S
-
F
I
V
KLPLI-
5
PsiBlast_PDB
91.25
30%
-93
- C2 -
4JAU
1
?
A:
[7-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
E
L
E
R
L
K
R
I
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
-
K
G
Y
A
E
M
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
--
F
E
S
-
N
V
P
C
P
V
E
A
YI
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
KDA
P
D
K
---
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
--
S
---------
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
V
G
-
K
-
G
-
S
R
-
F
F
V
W
I
P
---
7
PsiBlast_PDB
90.95
29%
-79
- C2 -
4JAV
6
?
A:
[3-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
T
E
--
S
K
E
L
E
R
L
K
R
I
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
-
K
A
Y
A
E
T
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
--
F
E
S
-
N
V
P
C
P
V
E
A
YI
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
KDA
P
D
K
---
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
--
S
S
L
T
YE
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
V
G
-
K
-
G
-
S
R
-
F
F
V
W
I
P
---
8
PsiBlast_PDB
87.71
29%
-82
- C2 -
2C2A
2
?
A:
[1-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
N
V
T
E
--
S
K
E
L
E
R
L
K
R
I
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
-
K
A
Y
A
E
T
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
--
F
E
S
-
N
V
P
C
P
V
E
A
YI
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
KDA
P
D
K
---
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
-----------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
V
G
-
K
-
G
-
S
R
-
F
F
V
W
I
P
---
4
PsiBlast_PDB
87.14
30%
-79
- C2 -
4JAS
2
?
A:
[13-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
R
I
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
-
K
G
Y
A
E
M
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
--
F
E
S
-
N
V
P
C
P
V
E
A
YI
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
KDA
P
D
K
---
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
--
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
V
G
-
K
-
G
-
S
R
-
F
F
V
W
I
P
---
3
PsiBlast_PDB
85.97
25%
-81
- C2 -
4U7O
1
?
A:
[27-261]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
Q
K
I
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
-
R
S
Y
I
E
A
L
S
D
G
A
W
K
-
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
--
N
Y
V
L
D
R
F
D
M
I
L
KK
D
----
D
N
P
A
K
Y
Y
T
I
K
R
E
F
T
K
-
R
-
D
L
W
V
E
I
--
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
P
---
D
G
G
---
V
V
T
C
R
L
L
--
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
--
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
-
S
V
E
-
G
-
K
-
G
-
S
T
-
F
Y
I
S
L
P
---
6
PsiBlast_PDB
84.43
29%
-77
- C2 -
3DGE
3
?
A:
[14-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
I
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
-
K
A
Y
A
E
T
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
--
F
E
S
-
N
V
P
C
P
V
E
A
YI
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
KDA
P
D
K
---
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
--
S
S
L
T
YE
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
V
G
-
K
-
G
-
S
R
-
F
F
V
W
I
P
---
40
HHSearch
83.97
30%
-85
- C2 -
2C2A
2
?
A:
[18-247]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
-
K
A
Y
A
E
T
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
--
E
S
A
V
N
A
I
K
-----
E
----
F
A
S
S
H
N
V
N
V
L
F
E
S
N
V
P
C
-
P
V
E
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
---
K
D
A
P
D
K
Y
V
K
V
I
L
D
--
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
-----------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
-
S
-
E
-
V
G
K
-
G
-
S
R
-
F
F
V
W
I
P
K
--
17
PsiBlast_PDB
83.06
26%
-65
- C2 -
4CB0
6
CPXA_ECOLI
A:
[74-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
M
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
--
T
A
L
L
R
R
R
S
G
-
E
S
K
E
L
----
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
--
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
16
PsiBlast_PDB
82.60
26%
-70
- C2 -
4BIV
2
CPXA_ECOLI
A:
[74-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
M
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
--
T
A
L
L
R
R
R
S
G
-
E
S
K
E
L
----
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
EA
R
D
R
E
--
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
2
PsiBlast_PDB
82.59
25%
-88
- C2 -
4U7N
-
?
A:
[39-261]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
-
R
S
Y
I
E
A
L
S
D
G
A
W
K
-
D
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
--
N
Y
V
L
D
R
F
D
M
I
L
K
K
D
----
D
N
---
Y
Y
T
I
K
R
E
F
T
K
-
R
-
D
L
W
V
E
I
--
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
P
---
D
G
G
---
V
V
T
C
R
L
L
--
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
-------------
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
-
S
V
E
-
G
-
K
-
G
-
S
T
-
F
Y
I
S
L
P
---
14
PsiBlast_PDB
81.57
28%
-81
- C2 -
4BIX
3
CPXA_ECOLI
A:
[83-294]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
E
S
-
K
E
L
E
-
R
I
E
T
E
-----
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
----------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
13
PsiBlast_PDB
81.55
28%
-78
- C2 -
4BIW
5
CPXA_ECOLI
A:
[83-294]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
E
S
-
K
E
L
E
-
R
I
E
T
E
-----
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
--
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
18
PsiBlast_PDB
80.17
27%
-76
- C2 -
4BIZ
3
CPXA_ECOLI
A:
[83-294]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
D
I
S
E
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
E
S
-
K
E
L
E
-
R
I
E
T
E
-----
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
----
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
12
PsiBlast_PDB
80.10
28%
-80
- C2 -
4BIU
-
CPXA_ECOLI
A:
[83-294]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
E
S
-
K
E
L
E
-
R
I
E
T
E
-----
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
------------
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
15
PsiBlast_PDB
78.67
28%
-86
- C2 -
4BIY
3
CPXA_ECOLI
A:
[83-294]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
E
S
-
K
E
L
E
-
R
I
E
T
E
-----
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
--
S
E
V
L
D
N
A
A
-----
F
----
E
A
E
Q
M
G
K
S
L
T
V
N
F
P
P
-
G
-
P
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-----
H
T
---
K
I
E
V
G
F
A
--
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
-----------
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
-
P
-
L
-
G
-
G
-
L
R
-
L
V
I
W
L
P
L
--
9
PsiBlast_PDB
72.86
29%
-50
- C2 -
4Q20
-
DIVL_CAUCR
A:
[35-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
-
I
G
Y
S
E
L
L
E
R
A
D
---
S
E
-
R
G
R
N
H
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
D
M
A
Q
I
D
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
A
Q
E
R
A
L
K
D
-----
A
----
Q
L
G
G
V
T
L
A
V
E
C
E
E
D
V
-
G
---
L
I
R
G
--
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
P
---
P
G
G
---
R
V
T
L
S
A
R
--
R
A
L
G
E
V
R
L
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
G
R
D
--
R
G
------
G
P
G
L
G
L
A
L
V
K
A
L
V
E
L
H
G
G
W
V
A
L
E
-
S
-
E
-
P
-
G
-
N
-
G
S
T
F
T
C
H
L
P
---
1
PsiBlast_PDB
71.86
27%
-66
- C2 -
4I5S
-
?
A:
[211-432]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
-
K
S
Y
L
E
A
L
D
D
G
A
L
T
-
E
S
V
A
P
S
F
I
-
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
-----
S
H
L
D
V
E
L
T
N
F
T
A
F
M
--
N
Y
I
L
D
R
F
D
-----
Q
I
Q
SQ
Q
S
T
----
E
I
I
R
D
Y
P
D
-
K
-
S
V
W
I
E
I
--
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P
---
D
G
G
---
K
V
T
I
T
M
Q
--
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
--
K
A
R
-------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
-
S
-
E
-
E
-
G
-
E
G
S
T
-
F
T
I
V
L
P
---
50
HHSearch
71.55
32%
-98
* C2 *
3SL2
2
A:
[3-151]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
I
V
R
F
M
--
S
L
I
I
D
R
F
E
-----
M
----
T
-
K
E
Q
--
E
F
I
R
N
L
P
D
-
R
-
D
L
Y
V
E
I
--
D
Q
D
K
I
T
Q
V
L
D
N
I
I
S
N
A
L
K
Y
S
P
---
E
G
G
---
H
V
T
F
S
I
D
V
N
E
E
E
E
L
L
Y
I
S
V
K
D
E
G
I
G
I
P
K
K
D
V
E
K
V
F
D
R
F
Y
R
V
D
--------
L
G
G
T
G
L
G
L
A
I
A
K
E
M
V
Q
A
H
G
G
D
I
W
A
D
-
S
-
I
-
E
-
G
K
G
-
T
T
-
I
T
F
T
L
P
Y
--
29
Fugue
70.15
20%
-62
- C2 -
4I5S
-
?
A:
[37-432]
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
L
K
V
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
M
T
D
G
V
L
A
T
D
R
S
G
K
I
T
V
-
I
N
D
M
A
Q
K
Q
L
N
V
T
R
E
Q
A
L
E
C
N
I
L
D
I
L
DDDSY
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
R
R
D
E
Y
D
E
F
I
T
L
R
I
R
F
A
L
N
R
R
E
S
G
F
I
S
G
L
I
A
V
L
H
D
A
-
T
E
Q
E
K
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
-
K
S
Y
L
E
A
L
D
D
G
A
L
T
-
E
S
V
A
P
S
F
I
-
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
S
H
-----
L
D
V
E
L
T
N
F
T
A
F
M
--
N
Y
I
L
D
R
F
D
-----
Q
----
I
Q
S
Q
Q
S
T
E
I
I
R
D
Y
P
D
-
K
-
S
V
W
I
E
I
--
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P
---
D
G
G
---
K
V
T
I
T
M
Q
--
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
--
K
A
R
-------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
-
S
-
E
-
E
-
G
-
E
G
S
T
-
F
T
I
V
L
P
---
28
Fugue
69.97
22%
-73
- C2 -
1ID0
2
A:
[1-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
L
H
P
V
A
P
L
L
--
D
N
L
T
S
A
L
N
-----
K
----
V
Y
Q
R
K
G
V
N
I
S
L
D
I
S
--
P
-
E
I
S
F
V
G
--
E
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
C
-----
L
E
---
F
V
E
I
S
A
R
--
Q
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
R
E
V
I
F
D
R
G
Q
R
V
D
--
T
L
R
P
----
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
Q
Y
E
G
K
I
V
A
G
-
E
-
S
-
M
-
L
-
G
G
A
R
-
M
E
V
I
F
G
R
Q
H
10
PsiBlast_PDB
68.27
30%
-45
- C2 -
4KP4
4
ENVZ_ECOLI
A:
[12-213]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
L
L
M
A
G
V
S
H
D
L
R
T
P
L
T
R
I
-
R
A
Y
A
E
T
I
Y
N
S
L
G
E
L
D
L
S
T
L
K
E
L
A
E
S
I
N
K
D
I
E
E
C
N
A
I
I
E
Q
F
I
D
Y
L
R
---
T
G
Q
E
M
P
M
E
M
A
D
L
N
A
V
L
--
G
E
V
I
A
A
E
S
-----
G
----
Y
--
E
R
E
I
E
T
A
L
Y
P
G
S
-
I
-
E
V
K
M
----
H
P
L
S
I
K
R
A
V
A
N
M
V
V
N
A
A
R
Y
G
-----
N
G
---
W
I
K
V
S
S
G
--
T
E
P
N
R
A
W
F
Q
V
E
D
D
G
P
G
I
A
P
E
Q
R
K
H
L
F
Q
P
F
V
R
G
D
--
S
A
R
T
--
I
S
G
T
G
L
G
L
A
I
V
Q
R
I
V
D
N
H
N
G
M
L
E
L
G
-
T
-
S
-
E
-
R
---------------