@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2495: (2016-04-04 )
MTTETAEKVEYIIETKDVDLFYGSKQALQKIALNIKKNQVTALIGPSGCGKSTFLRTLNRMNDLIPNVKTTGEIHIGGENVQDPKIDMVNLRKKVGMVFQQANPFPFSIYDNVAYGPRMHGIKDKKVLDEIVERSLRQAALWEEVHDRLDRSAIGMSGGQQQRLCIARVLAVKPDVILMDEPTSALDPISTAKVEDLILELKKDYTIVIVTHNMQQASRISDETAFFLNGRIVEFADTTSIFTNPAEKETEDYISGRFG
Atome Classification :
(36 SA)
.........10........20..-....--..30........40........50........60........70........80-----.--...-----------....90-----.----........100....-.-..110.....----..120.......--130...----....140.....-----------..150.......160.......170.......180......-.190-.......200-.-.--.....210.......220.......230.......240.......250.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTT
E
T
A
E
K
V
E
Y
I
I
ETK
D
V
D
L
FYG-
S
K
Q
A
--
L
Q
K
I
A
L
N
IKK
N
Q
V
T
A
L
IGPSGC
G
K
S
T
F
L
R
T
L
N
R
M
N
D
LIPNVKTT
G
E
I
H
IGGENV-----Q--DPK-----------
I
D
M
V
N
------
L
----
R
K
K
V
G
M
V
F
QQANPF
P
-
F
-
S
IYDNVAYGP----RMHGI
K
D
K
K
V
L
D
--
E
I
V
E
R
S
----
L
R
Q
A
A
L
W
E
E
V
H
D
-----------
R
L
D
R
S
AIGMSGG
Q
Q
Q
R
L
C
I
A
R
V
LAVKP
D
V
I
L
MDEPTSALDP-I
S
T
A
-
K
V
E
D
L
I
L
E
LK-K-D--
Y
T
I
V
I
V
TH
N
M
Q
Q
A
SRISDE
T
A
F
F
LN
G
R
I
V
E
F
ADTTSIFTNPA
E
K
E
T
E
D
Y
ISGRFG
25
PsiBlast_CBE
91.72
36%
-90
- C1 -
4U02
1
?
B:
[1-239]
--------
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
-
P
L
H
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
-----
Q
E
G
E
V
V
V
D
G
L
S
V
-----
K
--
D
D
R
-----------
A
-
L
R
E
------
I
----
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
-
T
V
L
E
N
V
T
L
A
P
MRVR
R
W
P
R
E
K
A
E
K
K
A
L
--
E
L
L
E
R
V
------------
G
I
L
D
-----------
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
----
24
PsiBlast_CBE
91.46
36%
-89
- C1 -
4U02
1
?
C:
[1-239]
--------
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
-
P
L
H
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
-----
Q
E
G
E
V
V
V
D
G
L
S
V
-----
K
--
D
D
R
-----------
A
-
L
R
E
------
I
----
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
-
T
V
L
E
N
V
T
L
A
P
MRVR
R
W
P
R
E
K
A
E
K
K
A
L
--
E
L
L
E
R
V
------------
G
I
L
D
-----------
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
----
84
HHSearch
91.26
34%
-89
- C1 -
1B0U
4
HISP_SALTY
A:
[5-255]
----------
N
K
L
H
V
I
D
L
H
K
R
Y
G
-
G
H
E
V
--
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
-----
S
E
G
A
I
I
V
N
G
Q
N
I
-----
N
--
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
------
L
----
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
-
T
V
L
E
N
V
M
E
A
P
----
I
Q
V
L
G
L
S
K
H
D
A
R
--
E
R
A
L
K
Y
----
L
A
K
V
G
I
D
E
R
A
Q
--------------
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
-
E
L
V
G
-
E
V
L
R
I
M
Q
Q
L
A
E
E
-
G
--
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
G
---
6
PsiBlast_PDB
90.63
36%
-93
- C1 -
4U00
3
?
A:
[3-239]
----------
P
I
I
R
I
R
N
L
H
K
W
F
G
-
P
L
H
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
-----
Q
E
G
E
V
V
V
D
G
L
S
V
-----
K
--
D
D
R
-----------
A
-
L
R
E
------
I
----
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
-
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
--
E
L
L
E
R
V
------------
G
I
L
D
-----------
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
----
7
PsiBlast_PDB
90.57
36%
-91
- C1 -
4U02
1
?
A:
[1-239]
--------
M
E
P
I
I
R
I
R
N
L
H
K
W
F
G
-
P
L
H
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
-----
Q
E
G
E
V
V
V
D
G
L
S
V
-----
K
--
D
D
R
-----------
A
-
L
R
E
------
I
----
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
-
T
V
L
E
N
V
T
L
A
P
MRVR
R
W
P
R
E
K
A
E
K
K
A
L
--
E
L
L
E
R
V
------------
G
I
L
D
-----------
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
----
23
PsiBlast_CBE
90.44
36%
-88
- C1 -
4U02
1
?
D:
[2-239]
---------
E
P
I
I
R
I
R
N
L
H
K
W
F
G
-
P
L
H
V
--
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
-----
Q
E
G
E
V
V
V
D
G
L
S
V
-----
K
--
D
D
R
-----------
A
-
L
R
E
------
I
----
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
-
T
V
L
E
N
V
T
L
A
P
MRVR
R
W
P
R
E
K
A
E
K
K
A
L
--
E
L
L
E
R
V
------------
G
I
L
D
-----------
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
----
33
PsiBlast_CBE
89.86
36%
-92
- C1 -
2OLK
2
?
B:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
10
PsiBlast_PDB
89.09
36%
-90
- C1 -
2OUK
1
?
A:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
32
PsiBlast_CBE
88.65
36%
-88
- C1 -
2OLK
1
?
C:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
29
PsiBlast_CBE
88.43
36%
-86
- C1 -
2OUK
1
?
C:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
26
PsiBlast_CBE
88.26
36%
-96
- C1 -
3C4J
4
?
B:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
13
PsiBlast_PDB
87.57
36%
-86
- C1 -
3C41
3
?
J:
[13-242]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
8
PsiBlast_PDB
87.27
36%
-96
- C1 -
2OLJ
4
?
A:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
11
PsiBlast_PDB
86.94
36%
-86
- C1 -
2Q0H
4
?
A:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
34
PsiBlast_CBE
86.79
36%
-89
- C1 -
2OLJ
3
?
B:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
12
PsiBlast_PDB
86.24
36%
-85
- C1 -
3C4J
3
?
A:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
5
PsiBlast_PDB
85.79
36%
-87
- C1 -
4YMW
-
?
J:
[1-237]
-----------
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
L
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
-----
P
T
K
G
E
V
F
I
D
G
V
K
I
-----
N
--
N
G
K
-----------
V
N
I
N
K
------
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
-
T
A
I
E
N
I
T
L
A
P
----
V
K
V
K
K
M
N
K
K
E
A
E
--
E
L
A
V
D
L
----
L
A
K
V
G
L
L
----
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
K
-
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
----
31
PsiBlast_CBE
85.63
36%
-88
- C1 -
2OLK
1
?
D:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
35
PsiBlast_CBE
85.02
36%
-88
- C1 -
3C41
3
?
K:
[13-242]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
AMEL
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
22
PsiBlast_CBE
84.41
36%
-89
- C1 -
4YMU
2
?
A:
[1-237]
-----------
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
L
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
-----
P
T
K
G
E
V
F
I
D
G
V
K
I
-----
N
--
N
G
K
-----------
V
N
I
N
K
------
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
-
T
A
I
E
N
I
T
L
A
P
----
V
K
V
K
K
M
N
K
K
E
A
E
--
E
L
A
V
D
L
----
L
A
K
V
G
L
L
----
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
K
-
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
----
3
PsiBlast_PDB
83.58
36%
-87
- C1 -
4YMU
2
?
J:
[1-237]
-----------
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
L
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
-----
P
T
K
G
E
V
F
I
D
G
V
K
I
-----
N
--
N
G
K
-----------
V
N
I
N
K
------
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
-
T
A
I
E
N
I
T
L
A
P
----
V
K
V
K
K
M
N
K
K
E
A
E
--
E
L
A
V
D
L
----
L
A
K
V
G
L
L
----
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
K
-
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
----
27
PsiBlast_CBE
83.23
36%
-88
- C1 -
2Q0H
4
?
B:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
38
PsiBlast_CBE
83.08
32%
-86
- C1 -
1B0U
4
HISP_SALTY
A:
[11-255]
----------------
D
L
H
K
R
Y
G
-
G
H
E
V
--
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
-----
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
K
--
D
G
Q
-----------
L
K
V
A
D
K
N
Q
L
R
L
L
----
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
-
T
V
L
E
N
V
M
E
A
P
I---
Q
V
L
G
L
S
K
----
H
--
D
A
R
E
R
A
----
L
K
Y
L
A
K
V
G
I
D
E
R
-----------
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
-
E
L
V
G
-
E
V
L
R
I
M
Q
Q
L
A
-
E
-
E
G-
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
G
---
21
PsiBlast_CBE
82.76
36%
-87
- C1 -
4YMV
1
?
A:
[1-237]
-----------
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
L
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
-----
P
T
K
G
E
V
F
I
D
G
V
K
I
-----
N
--
N
G
K
-----------
V
N
I
N
K
------
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
-
T
A
I
E
N
I
T
L
A
P
----
V
K
V
K
K
M
N
K
K
E
A
E
--
E
L
A
V
D
L
----
L
A
K
V
G
L
L
----
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
K
-
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
----
9
PsiBlast_PDB
82.57
36%
-88
- C1 -
2OLK
1
?
A:
[34-263]
---------------------
F
G
-
S
L
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
-----
D
E
G
E
I
I
I
D
G
I
N
L
-----
K
--
A
K
D
-----------
T
N
L
N
K
------
V
----
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
-
T
V
L
N
N
I
T
L
A
P
--------
M
K
V
R
K
W
P
R
--
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
-----------
Y
P
D
----
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
G
-
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-
4
PsiBlast_PDB
80.68
36%
-88
- C1 -
4YMV
1
?
J:
[1-237]
-----------
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
L
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
-----
P
T
K
G
E
V
F
I
D
G
V
K
I
-----
N
--
N
G
K
-----------
V
N
I
N
K
------
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
-
T
A
I
E
N
I
T
L
A
P
----
V
K
V
K
K
M
N
K
K
E
A
E
--
E
L
A
V
D
L
----
L
A
K
V
G
L
L
----
D
-----------
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
-
E
M
V
K
-
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
----
50
PsiBlast_CBE
64.73
32%
-77
- C1 -
1L2T
4
Y796_METJA
A:
[20-223]
---------------------------
A
--
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
-----
P
T
E
G
E
V
Y
I
--
D
N
I
-----
K
--
T
N
D
-----------
L
D
D
D
E
------
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
-
L
L
T
A
L
E
N
V
E
L
-
P
----
L
I
F
K
Y
R
G
A
M
S
G
E
--
E
R
R
K
R
A
----
L
E
C
L
K
M
A
E
L
E
E
R
-----------
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
-
K
T
G
E
-
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
DG
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
---------------------------
52
PsiBlast_CBE
63.85
32%
-76
- C1 -
3TIF
7
Y796_METJA
A:
[20-223]
---------------------------
A
--
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
-----
P
T
E
G
E
V
Y
I
--
D
N
I
-----
K
--
T
N
D
-----------
L
D
D
D
E
------
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
-
L
L
T
A
L
E
N
V
E
L
-
P
----
L
I
F
K
Y
R
G
A
M
S
G
E
--
E
R
R
K
R
A
----
L
E
C
L
K
M
A
E
L
E
E
R
-----------
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
-
K
T
G
E
-
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
DG
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
---------------------------
51
PsiBlast_CBE
63.15
32%
-80
- C1 -
3TIF
6
Y796_METJA
B:
[20-223]
---------------------------
A
--
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
-----
P
T
E
G
E
V
Y
I
--
D
N
I
-----
K
--
T
N
D
-----------
L
D
D
D
E
------
L
TKIR
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
-
L
L
T
A
L
E
N
V
E
L
-
P
----
L
I
F
K
Y
R
G
A
M
S
G
E
--
E
R
R
K
R
A
----
L
E
C
L
K
M
A
E
L
E
E
R
-----------
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
-
K
T
G
E
-
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
DG
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
---------------------------
49
PsiBlast_CBE
63.11
32%
-78
- C1 -
1L2T
4
Y796_METJA
B:
[20-223]
---------------------------
A
--
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
-----
P
T
E
G
E
V
Y
I
--
D
N
I
-----
K
--
T
N
D
-----------
L
D
D
D
E
------
L
TKIR
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
-
L
L
T
A
L
E
N
V
E
L
-
P
----
L
I
F
K
Y
R
G
A
M
S
G
E
--
E
R
R
K
R
A
----
L
E
C
L
K
M
A
E
L
E
E
R
-----------
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
-
K
T
G
E
-
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
DG
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
---------------------------
53
PsiBlast_CBE
62.97
31%
-88
- C1 -
2ONJ
4
Y1866_STAAM
B:
[340-555]
------------
I
D
I
D
H
V
S
F
Q
Y
N
-
D
N
E
A
PI
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
-----
T
S
G
Q
I
L
I
D
G
H
N
I
-----
K
--
D
F
L
-----------
T
G
--
S
------
L
----
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
-
D
-
T
V
K
E
N
I
L
L
G
----------
R
P
T
A
T
D
E
--
E
V
V
E
---------
A
A
K
M
A
N
A
H
D
FIMNLPQGYDT
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
-
E
S
E
S
-
I
I
Q
E
A
L
D
V
L
S
-
K
-
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
V
E
-------------------------
54
PsiBlast_CBE
62.06
31%
-88
- C1 -
2ONJ
4
Y1866_STAAM
A:
[340-555]
------------
I
D
I
D
H
V
S
F
Q
Y
N
-
D
N
E
A
PI
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
-----
T
S
G
Q
I
L
I
D
G
H
N
I
-----
K
--
D
F
L
-----------
T
G
--
S
------
L
----
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
-
D
-
T
V
K
E
N
I
L
L
G
----------
R
P
T
A
T
D
E
--
E
V
V
E
---------
A
A
K
M
A
N
A
H
D
FIMNLPQGYDT
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
-
E
S
E
S
-
I
I
Q
E
A
L
D
V
L
S
-
K
-
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
V
E
-------------------------
55
PsiBlast_CBE
60.95
31%
-91
- C1 -
2HYD
3
Y1866_STAAM
B:
[340-555]
------------
I
D
I
D
H
V
S
F
Q
Y
N
-
D
N
E
A
PI
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
-----
T
S
G
Q
I
L
I
D
G
H
N
I
-----
K
--
D
F
L
-----------
T
G
--
S
------
L
----
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
-
D
-
T
V
K
E
N
I
L
L
G
----------
R
P
T
A
T
D
E
--
E
V
V
E
---------
A
A
K
M
A
N
A
H
D
FIMNLPQGYDT
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
-
E
S
E
S
-
I
I
Q
E
A
L
D
V
L
S
-
K
-
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
V
E
-------------------------
56
PsiBlast_CBE
60.56
31%
-91
- C1 -
2HYD
3
Y1866_STAAM
A:
[340-555]
------------
I
D
I
D
H
V
S
F
Q
Y
N
-
D
N
E
A
PI
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
-----
T
S
G
Q
I
L
I
D
G
H
N
I
-----
K
--
D
F
L
-----------
T
G
--
S
------
L
----
R
N
Q
I
G
L
V
Q
Q
D
N
I
L
F
S
-
D
-
T
V
K
E
N
I
L
L
G
----------
R
P
T
A
T
D
E
--
E
V
V
E
---------
A
A
K
M
A
N
A
H
D
F
I
M
N
LPQGYDT
E
V
G
E
R
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
-
E
S
E
S
-
I
I
Q
E
A
L
D
V
L
S
-
K
-
D
--
R
T
T
L
I
V
A
H
R
L
S
T
I
T
H
-
A
D
K
I
V
V
I
E
N
G
H
I
V
E
-------------------------
17
PsiBlast_PDB
59.68
32%
-86
- C1 -
1VCI
1
?
A:
[22-240]
---------------------
F
G
-
N
F
T
A
--
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
-----
P
T
E
G
R
I
Y
F
G
D
R
D
V
-----
T
YL
P
P
K
---------------------------
D
R
N
I
S
M
V
F
Q
------H
M
-
T
V
Y
E
N
I
A
F
P
---------
L
--
K
K
F
P
K
--
D
E
I
D
K
R
----
V
R
W
A
A
E
L
L
Q
I
E
E
-----------
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
-
L
-
K
--
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
--------------
67
PsiBlast_CBE
55.14
31%
-79
- C1 -
3VX4
3
?
A:
[44-248]
---------------------
Y
G
F
G
R
D
T
--
L
S
D
I
N
L
S
I
K
K
G
S
K
V
S
L
V
G
A
S
G
S
G
K
T
T
L
A
K
L
I
--
V
N
F
Y
E
P
N
---
K
G
I
V
R
I
N
G
N
D
L
-----
K
----
V
-----------
I
D
K
T
A
------
L
----
R
R
H
I
S
Y
L
P
Q
Q
A
Y
V
F
S
-
G
-
S
I
M
D
N
L
V
L
G
A
----
K
-
E
G
T
S
Q
E
D
I
I
R
A
C
E
I
A
E
I
R
----
S
D
I
E
Q
M
P
Q
G
Y
Q
T
-----------
E
L
S
D
G
A
-
G
I
S
G
G
Q
K
Q
R
I
A
L
A
R
A
L
L
T
Q
A
P
V
L
I
L
D
A
A
T
S
S
L
D
I
-
L
T
E
K
-
K
I
I
S
N
L
L
Q
M
T
-
E
-
K
---
T
I
I
F
V
A
H
R
L
S
I
S
Q
R
-
T
D
E
V
I
V
M
D
Q
G
K
I
V
E
-------------------------