@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2556: (2016-04-04 )
MPIVNMTDMLKKALAGKYAVGQFNINNLEWTQAILKAAEAEKAPVILGVSEGAAKYMGGFKTVVKMTEGLVEDLKITVPVAIHLDHGSSFDSCKAAIDAGFSSVMIDGSHHPIDENIAMTKQVVDYAHAKGVSVEAEIGTVGGDEDGVTGGINYADPQECLRVVKEANIDALAAALGSVHGPYHGEPVLGFDEMKEISELTGAPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQIVWTAAVREKLATDDKVYDPRKVIGPGVDAIIKTVTEKIQEFGSNGKA
Atome Classification :
(27 SA)
--.....---....10........20........30........40........50.......--.---60..-------......70.---..-.....80......-----------..90.--------------.......100.......110.......120.......130.......140.......150..--..---....160.....-----..170.......180-..----.-.--.--...190.......-----------200.--......210--------------------...---------------------.---------------------.---------------------...220.......230.......240.......250------------.-.-......260.......270.......280..-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MPIV
N
---
M
T
D
M
L
K
K
A
LAGK
Y
A
V
G
Q
F
NIN
N
L
E
W
T
Q
A
I
L
K
A
AEAEKA
P
V
I
L
G
VSE
G
A
A
K
Y
M
G
--
G
---
F
K
T
V
-------
V
K
M
T
E
G
L
V
E---D
L
-
K
I
T
V
P
V
A
I
H
LDHG-----------S
S
F
D
S
--------------
C
K
A
A
I
D
AGF
S
S
V
M
IDGSHHPID
E
N
I
A
M
T
K
Q
V
V
D
Y
AHAKG
V
S
V
E
A
E
IGTVGGDEDGVTG-GIN--YA---
D
P
Q
E
C
L
R
V
V
K
EA-----
N
I
D
A
L
A
A
A
L
GSVHG--PY----H-G--E--PVL
G
F
D
E
M
K
E
I
S
E
-----------LTGA--
P
L
V
L
HGGS---------------------GI
P
---------------------
E
---------------------
H
---------------------
Q
I
K
K
A
I
E
LGH
S
K
INVNT
E
C
Q
I
V
W
T
A
A
V
R
E
KLATDD-------------K-V-YD
P
R
KVIGP
G
V
D
A
I
I
K
T
V
T
E
K
I
Q
E
FGSNGKA-
1
PsiBlast_PDB
97.78
67%
-89
- C2 -
3Q94
10
?
A:
[5-288]
---
P
L
V
S
---
M
K
E
M
L
N
K
A
L
E
G
K
Y
A
V
G
Q
F
N
M
N
N
L
E
W
T
Q
A
I
L
A
A
A
E
E
E
K
S
P
V
I
L
G
V
S
E
G
A
A
R
H
M
T
--
G
---
F
K
T
V
-------
V
A
M
V
K
A
L
I
E
---
E
M
-
N
I
T
V
P
V
A
I
H
L
D
H
G
-----------
S
S
F
E
K
--------------
C
K
E
A
I
D
A
G
F
T
S
V
M
I
D
A
S
H
H
P
F
E
E
N
V
E
T
T
K
K
V
V
E
Y
A
H
A
R
N
V
S
V
E
A
E
L
G
T
V
G
G
Q
E
D
D
V
I
A
E
G
V
I
--
Y
A
---
D
P
A
E
C
K
H
L
V
E
A
T
-----
G
I
D
C
L
A
P
A
L
G
S
V
H
G
--
P
Y
----
K
-
G
--
E
--
P
N
L
G
F
A
E
M
E
Q
V
R
D
-----------
F
T
G
V
--
P
L
V
L
H
G
G
T
---------------------
G
I
P
---------------------
T
---------------------
A
---------------------
D
I
E
K
A
I
S
L
G
T
S
K
I
N
V
N
T
E
N
Q
I
E
F
T
K
A
V
R
E
V
L
N
K
D
Q
-------------
E
-
V
-
Y
D
P
R
K
F
I
G
P
G
R
D
A
I
K
A
T
V
I
G
K
I
R
E
F
G
S
N
G
K
A
-
2
PsiBlast_PDB
93.38
65%
-94
- C2 -
4TO8
2
?
A:
[2-285]
---
P
L
V
S
---
M
K
E
M
L
I
D
A
K
E
N
G
Y
A
V
G
Q
Y
N
I
N
N
L
E
F
T
Q
A
I
L
E
A
S
Q
E
E
N
A
P
V
I
L
G
V
S
E
G
A
A
R
Y
M
S
--
G
---
F
Y
T
I
-------
V
K
M
V
E
G
L
M
H
---
D
L
-
N
I
T
I
P
V
A
I
H
L
D
H
G
-----------
S
S
F
E
K
--------------
C
K
E
A
I
D
A
G
F
T
S
V
M
I
D
A
S
H
S
P
F
E
E
N
V
A
T
T
K
K
V
V
E
Y
A
H
E
K
G
V
S
V
E
A
E
L
G
T
V
G
G
--
D
D
V
V
A
D
G
I
I
--
Y
A
---
D
P
K
E
C
Q
E
L
V
E
K
T
-----
G
I
D
A
L
A
P
A
L
G
S
V
H
G
----------------
P
K
L
G
F
K
E
M
E
E
I
G
L
-----------
S
T
G
L
--
P
L
V
L
H
G
G
T
---------------------
G
I
P
---------------------
T
---------------------
K
---------------------
D
I
Q
K
A
I
P
F
G
T
A
K
I
N
V
N
T
E
N
Q
I
A
S
A
K
A
V
R
D
V
L
N
N
D
K
-------------
E
-
V
-
Y
D
P
R
K
Y
L
G
P
A
R
E
A
I
K
E
T
V
K
G
K
I
K
E
F
G
T
S
N
R
A
-
21
PsiBlast_CBE
92.76
65%
-93
- C2 -
4TO8
2
?
B:
[2-285]
---
P
L
V
S
---
M
K
E
M
L
I
D
A
K
E
N
G
Y
A
V
G
Q
Y
N
I
N
N
L
E
F
T
Q
A
I
L
E
A
S
Q
E
E
N
A
P
V
I
L
G
V
S
E
G
A
A
R
Y
M
S
--
G
---
F
Y
T
I
-------
V
K
M
V
E
G
L
M
H
---
D
L
-
N
I
T
I
P
V
A
I
H
L
D
H
G
-----------
S
S
F
E
K
--------------
C
K
E
A
I
D
A
G
F
T
S
V
M
I
D
A
S
H
S
P
F
E
E
N
V
A
T
T
K
K
V
V
E
Y
A
H
E
K
G
V
S
V
E
A
E
L
G
T
V
G
G
--
D
D
V
V
A
D
G
I
I
--
Y
A
---
D
P
K
E
C
Q
E
L
V
E
K
T
-----
G
I
D
A
L
A
P
A
L
G
S
V
H
-----------------
P
K
L
G
F
K
E
M
E
E
I
G
L
-----------
S
T
G
L
--
P
L
V
L
H
G
G
T
---------------------
G
I
P
---------------------
T
---------------------
K
---------------------
D
I
Q
K
A
I
P
F
G
T
A
K
I
N
V
N
T
E
N
Q
I
A
S
A
K
A
V
R
D
V
L
N
N
D
K
-------------
E
-
V
-
Y
D
P
R
K
Y
L
G
P
A
R
E
A
I
K
E
T
V
K
G
K
I
K
E
F
G
T
S
N
R
A
-
53
HHSearch
84.08
47%
-82
* C2 *
2ISW
2
?
A:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
S
D
------
M
I
Y
L
-------
K
K
L
C
E
A
A
-----
L
E
K
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
S
V
S
V
E
A
E
L
G
T
L
-----------
V
Q
--
L
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
F
K
S-----
R
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
GGKMPDAV
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
4
PsiBlast_PDB
83.82
43%
-83
- C2 -
2ISV
2
?
A:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
-
S
--
D
---
M
I
Y
L
-------
K
K
L
C
E
A
A
L
E
---
K
--
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
S
V
S
V
E
A
E
L
G
-----------------
L
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
G
T
S
H
G
--
A
--------------
R
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
GGKMPDAV
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
5
PsiBlast_PDB
83.15
43%
-82
- C2 -
2ISW
2
?
A:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
-
S
--
D
---
M
I
Y
L
-------
K
K
L
C
E
A
A
L
E
---
K
--
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
S
V
S
V
E
A
E
L
G
T
L
-----------
V
Q
--
L
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
G
T
S
H
G
--
A
Y
KFKS---------
R
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
GGKMPDAV
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
22
PsiBlast_CBE
83.11
43%
-86
- C2 -
3GAK
4
?
B:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
-
S
--
D
---
M
I
Y
L
-------
K
K
L
C
E
A
A
L
E
---
K
--
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
G
V
S
V
E
A
E
L
G
------------------
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
G
T
S
H
G
--
A
Y
KFKS
E
---------
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
GGKMP
D
A
V
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
23
PsiBlast_CBE
82.98
43%
-83
- C2 -
2ISV
2
?
B:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
-
S
--
D
---
M
I
Y
L
-------
K
K
L
C
E
A
A
L
E
---
K
--
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
S
V
S
V
E
A
E
L
G
---------
Q
N
-
T
V
Q
--
L
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
G
T
S
H
G
--
A
Y
KF----------
I
R
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
GGKMPDAV
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
55
HHSearch
82.28
45%
-78
- C2 -
1RVG
8
?
A:
[1-305]
---
M
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
-----
A
K
-
E
A
R
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
---
K
-
D
A
L
--
L
T
---
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
K
G
R
--
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
AVP
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
EAA
G
I
H
---------------------
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
6
PsiBlast_PDB
81.49
40%
-83
- C2 -
1RV8
7
?
A:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
---------
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
G
R
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
EAAGIH
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
8
PsiBlast_PDB
81.08
41%
-79
- C2 -
2FJK
1
ALF_THECA
A:
[2-305]
----
L
V
T
---
G
L
E
I
L
R
K
A
R
A
E
G
Y
G
V
G
A
F
N
T
N
N
M
E
F
T
Q
A
I
L
E
A
A
E
E
M
K
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
R
M
V
V
A
L
A
Q
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
K
A
L
R
E
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
K
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
H
V
A
V
-
D
E
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
GR
P
F
I
D
H
P
R
L
A
R
I
A
K
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
---------------------
Q
E
L
V
E
R
F
R
A
A
G
G
E
I
G
EASGIH
P
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
V
R
E
T
L
G
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
54
HHSearch
80.85
39%
-85
- C2 -
1GVF
11
KBAY_ECOLI
A:
[2-284]
---
S
I
I
S
---
T
K
Y
L
L
Q
D
A
Q
A
N
G
Y
A
V
P
A
F
N
I
H
N
A
E
T
I
Q
A
I
L
E
V
C
S
E
M
R
S
P
V
I
L
A
G
T
P
G
T
F
K
H
I
A
------
L
E
E
I
-------
Y
A
L
C
S
A
Y
-----
S
T
-
T
Y
N
M
P
L
A
L
H
L
D
H
H
-----------
E
S
L
D
D
--------------
I
R
R
K
V
H
A
G
V
R
S
A
M
I
D
G
S
H
F
P
F
A
E
N
V
K
L
V
K
S
V
V
D
F
C
H
S
Q
D
C
S
V
E
A
E
L
G
R
L
G
---------
S
A
F
--
L
T
---
D
P
Q
E
A
K
R
F
V
E
L
T
-----
G
V
D
S
L
A
V
A
I
G
T
A
H
G
--
L
Y
----
S
-
K
--
T
--
P
K
I
D
F
Q
R
L
A
E
I
R
E
-----------
V
V
D
V
--
P
L
V
L
H
G
A
S
---------------------
D
V
P
---------------------
D
---------------------
E
---------------------
F
V
R
R
T
I
E
L
G
V
T
K
V
N
V
A
T
E
L
K
I
A
F
A
G
A
V
K
A
W
F
A
E
N
P
-------------
Q
-
G
-
N
D
P
R
Y
Y
M
R
V
G
M
D
A
M
K
E
V
V
R
N
K
I
N
V
C
G
S
A
N
R
I
-
3
PsiBlast_PDB
80.67
43%
-84
- C2 -
3GAK
4
?
A:
[2-307]
---
P
L
C
T
---
L
R
Q
M
L
G
E
A
R
K
H
K
Y
G
V
G
A
F
N
V
N
N
M
E
Q
I
Q
G
I
M
K
A
V
V
Q
L
K
S
P
V
I
L
Q
C
S
R
G
A
L
K
Y
-
S
--
D
---
M
I
Y
L
-------
K
K
L
C
E
A
A
L
E
---
K
--
H
P
D
I
P
I
C
I
H
L
D
H
G
-----------
D
T
L
E
S
--------------
V
K
M
A
I
D
L
G
F
S
S
V
M
I
D
A
S
H
H
P
F
D
E
N
V
R
I
T
K
E
V
V
A
Y
A
H
A
R
G
V
S
V
E
A
E
L
G
------------------
T
---
E
P
Q
D
A
K
K
F
V
E
L
T
-----
G
V
D
A
L
A
V
A
I
-----------------------
L
A
I
D
R
V
K
T
I
S
D
-----------
L
T
G
I
--
P
L
V
M
H
G
S
S
SVP
K
D
V
K
D
M
I
N
K
Y
G
G
K
MPDA
V
G
V
P
---------------------
I
---------------------
E
---------------------
S
I
V
H
A
I
G
E
G
V
C
K
I
N
V
D
S
D
S
R
M
A
M
T
G
A
I
R
K
V
F
V
E
H
P
-------------
E
-
K
-
F
D
P
R
D
Y
L
G
P
G
R
D
A
I
T
E
M
L
I
P
K
I
K
A
F
G
S
A
G
H
A
-
28
PsiBlast_CBE
80.57
40%
-80
- C2 -
1RV8
6
?
C:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
H
V
A
V
-
D
E
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
GR
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
26
PsiBlast_CBE
80.54
40%
-82
- C2 -
1RVG
6
?
B:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
H
V
A
V
-
D
E
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
GR
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
E
A
A
G
I
H
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
25
PsiBlast_CBE
80.48
40%
-82
- C2 -
1RVG
6
?
C:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
H
V
A
V
-
D
E
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
GR
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
31
PsiBlast_CBE
80.38
38%
-81
- C2 -
3N9R
14
?
Z:
[2-306]
----
L
V
K
---
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
-----------------
I
D
M
A
V
G
M
V
K
IMC
E
R
-
Y
P
H
I
P
V
A
L
H
L
D
H
G
-----------
T
T
F
E
S
--------------
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-------------
A
VLV
N
P
K
E
A
E
Q
F
V
K
E
S
-----
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
AF
K
F
----
K
-
G
--
E
--
P
K
L
D
F
E
R
L
Q
E
V
K
R
-----------
L
T
N
I
--
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
---------------------
N
VRKSYLDAGGDLKGSKGVPFE
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
-
K
V
A
N
E
D
-------------
K
-
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
--
24
PsiBlast_CBE
80.21
40%
-79
- C2 -
1RVG
5
?
D:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
H
V
A
V
-
D
E
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
GR
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
7
PsiBlast_PDB
80.21
40%
-81
- C2 -
1RVG
8
?
A:
[2-305]
----
L
V
T
---
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
-------
R
A
L
-------
T
L
M
A
V
E
L
A
K
---
E
A
-
R
--
V
P
V
A
V
H
L
D
H
G
-----------
S
S
Y
E
S
--------------
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
A
G
I
E
E
-------
K
--
D
A
LLT
N
P
E
E
A
R
I
F
M
E
R
T
-----
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
--
A
Y
----
K
-
G
--
K
G
R
P
F
I
D
H
A
R
L
E
R
I
A
R
-----------
L
V
P
A
--
P
L
V
L
H
G
A
S
---------------------
A
V
P
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
EAAGIH
P
---------------------
E
---------------------
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
-------------
K
-
E
-
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
-
32
PsiBlast_CBE
80.13
38%
-80
- C2 -
3N9R
2
?
U:
[2-306]
----
L
V
K
---
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
-----------------
I
D
M
A
V
G
M
V
K
IMC
E
R
-
Y
P
H
I
P
V
A
L
H
L
D
H
G
-----------
T
T
F
E
S
--------------
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-------------
A
VLV
N
P
K
E
A
E
Q
F
V
K
E
S
-----
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
AF
K
F
----
K
-
G
--
E
--
P
K
L
D
F
E
R
L
Q
E
V
K
R
-----------
L
T
N
I
--
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
---------------------
N
VRKSYLDAGGDLKGSKGVPFE
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
-
K
V
A
N
E
D
-------------
K
-
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
--
13
PsiBlast_PDB
79.83
38%
-86
- C2 -
1GVF
11
KBAY_ECOLI
A:
[2-283]
---
S
I
I
S
---
T
K
Y
L
L
Q
D
A
Q
A
N
G
Y
A
V
P
A
F
N
I
H
N
A
E
T
I
Q
A
I
L
E
V
C
S
E
M
R
S
P
V
I
L
A
G
T
P
G
T
F
K
H
I
A
------
L
E
E
I
-------
Y
A
L
C
S
A
Y
-----
S
T
-
T
Y
N
M
P
L
A
L
H
L
D
H
H
-----------
E
S
L
D
D
--------------
I
R
R
K
V
H
A
G
V
R
S
A
M
I
D
G
S
H
F
P
F
A
E
N
V
K
L
V
K
S
V
V
D
F
C
H
S
Q
D
C
S
V
E
A
E
L
G
R
L
G
--------------
S
A
FLT
D
P
Q
E
A
K
R
F
V
E
L
T
-----
G
V
D
S
L
A
V
A
I
G
T
A
H
G
--
L
Y
----
S
-
K
--
T
--
P
K
I
D
F
Q
R
L
A
E
I
R
E
-----------
V
V
D
V
--
P
L
V
L
H
G
A
S
---------------------
D
V
P
---------------------
D
---------------------
E
---------------------
F
V
R
R
T
I
E
L
G
V
T
K
V
N
V
A
T
E
L
K
I
A
F
A
G
A
V
K
A
W
F
A
E
N
P
-------------
Q
-
G
-
N
D
P
R
Y
Y
M
R
V
G
M
D
A
M
K
E
V
V
R
N
K
I
N
V
C
G
S
A
N
R
--
30
PsiBlast_CBE
79.63
38%
-81
- C2 -
3N9S
5
?
B:
[2-306]
----
L
V
K
---
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
-----------------
I
D
M
A
V
G
M
V
K
I
M
C
E
R
-
Y
P
H
I
P
V
A
L
H
L
D
H
G
-----------
T
T
F
E
S
--------------
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
---------------
A
VLV
N
P
K
E
A
E
Q
F
V
K
E
S
-----
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
AF
K
F
----
K
-
G
--
E
--
P
K
L
D
F
E
R
L
Q
E
V
K
R
-----------
L
T
N
I
--
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
---------------------
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
-
K
V
A
N
E
D
-------------
K
-
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
--
11
PsiBlast_PDB
79.16
38%
-82
- C2 -
3C56
3
ALF_HELPY
A:
[2-306]
----
L
V
K
---
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
-----------------
I
D
M
A
V
G
M
V
K
I
M
C
E
R
-
Y
P
H
I
P
V
A
L
H
L
D
H
G
-----------
T
T
F
E
S
--------------
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-------------
A
VLV
N
P
K
E
A
E
Q
F
V
K
E
S
-----
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
AF
K
F
----
K
-
G
--
E
--
P
K
L
D
F
E
R
L
Q
E
V
K
R
-----------
L
T
N
I
--
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
---------------------
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
-
K
V
A
N
E
D
-------------
K
-
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
--
38
PsiBlast_CBE
78.29
38%
-82
- C2 -
1GVF
12
KBAY_ECOLI
B:
[2-283]
---
S
I
I
S
---
T
K
Y
L
L
Q
D
A
Q
A
N
G
Y
A
V
P
A
F
N
I
H
N
A
E
T
I
Q
A
I
L
E
V
C
S
E
M
R
S
P
V
I
L
A
G
T
P
G
T
F
K
H
I
A
------
L
E
E
I
-------
Y
A
L
C
S
A
Y
-----
S
T
-
T
Y
N
M
P
L
A
L
H
L
D
H
H
-----------
E
S
L
D
D
--------------
I
R
R
K
V
H
A
G
V
R
S
A
M
I
D
G
S
H
F
P
F
A
E
N
V
K
L
V
K
S
V
V
D
F
C
H
S
Q
D
C
S
V
E
A
E
L
G
R
L
G
G
V
E
-----------
S
A
FLT
D
P
Q
E
A
K
R
F
V
E
L
T
-----
G
V
D
S
L
A
V
A
I
G
T
A
H
G
--
L
Y
----
S
-
K
--
T
--
P
K
I
D
F
Q
R
L
A
E
I
R
E
-----------
V
V
D
V
--
P
L
V
L
H
G
A
S
---------------------
D
V
P
---------------------
D
---------------------
E
---------------------
F
V
R
R
T
I
E
L
G
V
T
K
V
N
V
A
T
E
L
K
I
A
F
A
G
A
V
K
A
W
F
A
E
N
P
-------------
Q
-
G
-
N
D
P
R
Y
Y
M
R
V
G
M
D
A
M
K
E
V
V
R
N
K
I
N
V
C
G
S
A
N
R
--
10
PsiBlast_PDB
78.23
38%
-83
- C2 -
3C52
4
ALF_HELPY
A:
[2-306]
----
L
V
K
---
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
-----------------
I
D
M
A
V
G
M
V
K
I
M
C
E
R
-
Y
P
H
I
P
V
A
L
H
L
D
H
G
-----------
T
T
F
E
S
--------------
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
--------------VLV
N
P
K
E
A
E
Q
F
V
K
E
S
-----
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
AF
K
F
----
K
-
G
--
E
--
P
K
L
D
F
E
R
L
Q
E
V
K
R
-----------
L
T
N
I
--
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
---------------------
N
V
R
K
S
Y
L
D
A
G
G
D
L
K
GSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
-
K
V
A
N
E
D
-------------
K
-
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
--
45
Fugue
78.01
40%
-83
- C2 -
1GVF
11
KBAY_ECOLI
A:
[2-285]
SI
I
S
------
T
K
Y
L
L
Q
D
A
Q
A
N
G
Y
A
V
P
A
F
N
I
H
N
A
E
T
I
Q
A
I
L
E
V
C
S
E
M
R
S
P
V
I
L
A
G
T
P
G
T
F
K
------
H
IA
L
E
E
I
-------
Y
A
L
C
S
A
Y
S
T
---
T
Y
-
N
--
M
P
L
A
L
H
L
D
H
H
ES
L
D
D
I
R
R
K
V
H
A
-------------------------
G
V
R
S
A
M
I
D
G
S
H
F
P
F
A
E
N
V
K
L
V
K
S
V
V
D
F
C
H
S
Q
D
C
S
V
E
A
E
L
G
R
L
G
S
-----------AF
L
T
---
D
P
Q
E
A
K
R
F
V
E
L
T
-----
G
V
D
S
L
A
V
A
I
G
T
A
H
G
--
L
Y
----
S
-
K
--
T
--
P
K
I
D
F
Q
R
L
A
E
I
R
E
-----------
V
V
--D
V
P
L
V
L
H
G
A
S
---------------------
D
V
P
---------------------
D
---------------------
E
---------------------
F
V
R
R
T
I
E
L
G
V
T
K
V
N
V
A
T
E
L
K
I
A
F
A
G
A
V
K
A
W
F
A
E
N
P
--------------Q
G
-
N
D
P
R
Y
Y
M
R
V
G
M
D
A
M
K
E
V
V
R
N
K
I
N
V
C
G
S
A
N
R
I
S
56
HHSearch
69.50
32%
-72
- C2 -
3ELF
3
ALF_MYCTU
A:
[2-341]
---
P
I
A
T
P
E
V
Y
A
E
M
L
G
Q
A
K
Q
N
S
Y
A
F
P
A
I
N
C
T
S
S
E
T
V
N
A
A
I
K
G
F
A
D
A
G
S
D
G
I
I
Q
F
S
T
G
G
A
E
F
G
S
GL
G
---
V
K
D
M
V
T
G
A
V
A
L
A
E
F
T
H
V
I
-----
A
A
-
K
Y
P
V
N
V
A
L
H
T
D
H
C
-----------
P
K
D
K
L
DSY
V
R
P
L
L
A
I
S
A
Q
R
V
S
K
G
G
N
P
L
F
Q
S
H
M
W
D
G
S
A
V
P
I
D
E
N
L
A
I
A
Q
E
L
L
K
A
A
A
A
A
K
I
I
L
E
I
E
I
G
V
V
G
G
-------------
Y
T
---
S
P
E
D
F
E
K
T
I
E
A
L
GAGEH
G
K
Y
L
L
A
A
T
F
G
N
V
H
G
--
V
Y
----
K
P
G
--
N
--
V
K
L
R
P
D
I
L
A
Q
G
Q
Q
V
A
A
A
K
L
GLPAD
A
K
P
F
--
D
F
V
F
H
G
G
S
---------------------
G
S
L
---------------------
K
---------------------
S
---------------------
E
I
E
E
A
L
R
Y
G
V
V
K
M
N
V
D
T
D
T
Q
Y
A
F
T
R
P
I
A
G
H
M
F
T
N
Y
DGVLKVDGEVGVK
K
-
V
-
Y
D
P
R
S
Y
L
K
K
A
E
A
S
M
S
Q
R
V
V
Q
A
C
N
D
L
H
C
A
G
K
S
-