@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2601: (2016-04-05 )
VAESFVRLEHVFYKYEDTEKYAVKDVSISAQKGEWVALVGHNGSGKSTIAKLLNGLLFPEDGLIKIGHFVLSEKNIWEIRRQVGMVFQNPDNQFVGATVQDDVAFGLENHGVPHDTMVERVESALNEVGMQSYALHEPARLSGGQKQRVAIAGVLALQPDVIILDEATSMLDPRGRAEVMETIRIMREQEDITVISITHDLDEVLFADRVIVMNKGEIHSEGTPKEIFQQADAMREIGLGVPFIIELQEKLVAGGFETGSTVLSEGALLDQLWKLNSNN
Atome Classification :
(53 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.....--..--.20-..---.......30........40........50......-..60.....-..-.70--.---.--.--.---.---..--..---80--.-........90........100....-...110.-----------.-------------......120---.--------..-----....--.130--.-------........140.......150.......160.......170.......180.-......190--.......200--...-.-.-.----..210.......220.......230-.......--.240------.......----------.250.......260.----...--------...270.......--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VA
E
S
F
V
R
L
E
H
V
F
Y
KYE--DT--E
K
--
Y
A
---
V
K
D
V
S
I
SAQKG
E
W
V
A
L
VGHNGS
G
K
S
T
I
A
K
L
L
N
G
LL-FPEDG
L
I
K
I
-
G
H
-
F
V---L---S--E--K---
N
---
I
W
--
E
I
---
R
---
R
-QVG
M
V
F
QNPDN
Q
F
V
G
A
T
V
Q
D
D
V
A
F
G
-
L
ENH-GV-----------
P
-------------
H
D
T
M
V
E
R
V
----
E
--------
S
A
-----
L
N
E
V--G
M
----
Q
-------
S
YALH
E
P
A
RLSGGQ
K
Q
R
V
A
I
A
G
V
L
ALQP
D
V
I
I
LDE
A
T
SMLDPR
G
R
A
E
V
M
E
T
I
-
R
I
M
REQED
I
--
T
V
I
S
ITH
D
L
---
D
E
V
-
L
-F-A----
D
R
V
I
V
M
NKGEIHSEG
T
P
K
E
I
F
Q
Q
A
--
D
A
M
R
E
IG--LGV-------
P
F
I
I
E
L
Q
----------
E
K
L
VAGGFET
G
S
T
V
L
----SE
G
--------
A
L
L
D
Q
L
W
KLNSNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.25
48%
-98
- C1 -
4HUQ
-
ECFA1_LACBA
B:
[3-277]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
I
I
S
V
D
H
L
T
Y
Q
Y
D
--
E
N
--
Q
A
--
P
A
---
L
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
G
S
G
K
S
T
L
A
K
S
L
D
G
L
L
-
P
F
T
Q
G
S
V
T
V
-
G
G
-
I
T
---
L
---
T
--
P
--
E
---
T
---
V
W
--
Q
V
---
R
---
E
-
Q
I
G
M
I
F
Q
N
P
D
N
Q
F
V
G
A
T
V
E
D
D
V
A
F
G
-
L
E
N
R
-
Q
I
-----------
S
-------------
R
D
E
M
V
P
R
V
----
Q
--------
A
A
-----
L
A
Q
V
--
G
M
----
T
-------
S
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
A
G
I
V
A
I
A
P
K
I
L
I
L
D
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
-
R
Q
L
R
Q
Q
Q
N
L
--
T
V
I
S
I
T
H
D
I
---
D
E
A
-
A
-
S
-
A
----
D
R
V
L
V
I
D
D
G
R
L
V
D
E
A
V
P
S
Q
I
F
E
R
G
--
T
Q
L
V
E
M
G
--
L
D
L
-------
P
F
T
E
K
L
K
----------
A
A
L
R
Q
R
G
I
T
P
P
T
T
Y
Q
----
T
A
A
--------
E
M
E
E
W
L
W
Q
S
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
92.11
48%
-89
- C1 -
4HZU
-
ECFA1_LACBA
A:
[2-277]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
N
I
I
S
V
D
H
L
T
Y
Q
Y
-------
Q
A
--
P
A
---
L
T
D
V
S
F
T
V
H
A
G
E
W
L
A
I
V
G
H
N
G
S
G
K
S
T
L
A
K
S
L
D
G
L
L
-
P
F
T
Q
G
S
V
T
V
-
G
G
-
I
T
---
L
---
T
--
P
--
E
---
T
---
V
W
--
Q
V
---
R
---
E
-
Q
I
G
M
I
F
Q
N
P
D
N
Q
F
V
G
A
T
V
E
D
D
V
A
F
G
-
L
E
N
R
-
Q
I
-----------
S
-------------
R
D
E
M
V
P
R
V
----
Q
--------
A
A
-----
L
A
Q
V
--
G
M
----
T
-------
S
F
A
Q
R
E
P
S
S
L
S
G
G
Q
K
Q
R
V
A
L
A
G
I
V
A
I
A
P
K
I
L
I
L
D
E
A
T
S
M
L
D
P
Q
G
R
I
E
M
L
A
I
V
-
R
Q
L
R
Q
Q
Q
N
L
--
T
V
I
S
I
T
H
D
I
---
D
E
A
-
A
-
S
-
A
----
D
R
V
L
V
I
D
D
G
R
L
V
D
E
A
V
P
S
Q
I
F
E
R
G
--
T
Q
L
V
E
M
G
--
L
D
L
-------
P
F
T
E
K
L
K
----------
A
A
L
R
Q
R
G
I
T
P
P
T
T
Y
Q
----
T
A
A
--------
E
M
E
E
W
L
W
Q
S
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.17
40%
-109
- C1 -
4MKI
4
ECFA2_CALS4
A:
[7-272]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
V
E
N
V
S
F
I
Y
N
--
E
G
--
T
P
--
Y
A
TVA
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
-
K
P
S
K
G
K
I
Y
I
-
N
G
-
I
D
---
I
---
T
--
D
--
K
---
K
---
V
S
L
K
D
I
---
R
---
K
-
Q
V
G
L
V
F
Q
Y
P
E
Y
Q
L
F
E
E
T
V
F
K
D
I
A
F
G
-
P
S
N
L
-
G
L
-----------
S
-------------
E
E
E
V
K
E
R
V
----
Y
--------
E
A
-----
M
E
I
V
--
G
I
S---
K
-------
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
-
K
E
I
H
D
K
Y
K
M
--
I
T
I
L
V
S
H
N
M
---
E
D
I
-
A
R
I
-
A
----
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
R
E
A
--
E
R
L
E
K
I
G
--
L
S
V
-------
P
Q
I
T
S
L
A
----------
R
E
L
R
K
R
G
V
P
I
P
P
D
V
L
----
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
85.73
40%
-107
- C1 -
4MKI
4
ECFA2_CALS4
B:
[7-272]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
V
E
N
V
S
F
I
Y
N
--
E
G
--
T
P
--
Y
A
TVA
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
-
K
P
S
K
G
K
I
Y
I
-
N
G
-
I
D
---
I
---
T
--
D
--
K
---
K
---
V
S
L
K
D
I
---
R
---
K
-
Q
V
G
L
V
F
Q
Y
P
E
Y
Q
L
F
E
E
T
V
F
K
D
I
A
F
G
-
P
S
N
L
-
G
L
-----------
S
-------------
E
E
E
V
K
E
R
V
----
Y
--------
E
A
-----
M
E
I
V
--
G
I
S---
K
-------
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
-
K
E
I
H
D
K
Y
K
M
--
I
T
I
L
V
S
H
N
M
---
E
D
I
-
A
R
I
-
A
----
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
R
E
A
--
E
R
L
E
K
I
G
--
L
S
V
-------
P
Q
I
T
S
L
A
----------
R
E
L
R
K
R
G
V
P
I
P
P
D
V
L
----
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
HHSearch
76.13
39%
-105
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[4-254]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
Y
I
L
K
V
E
E
L
N
Y
N
Y
S
--
D
G
---
T
--
H
A
---
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
-
K
P
S
S
G
R
I
L
F
-
D
N
-
K
P
---
I
---
D
--
Y
--
S
R
K
-
G
---
I
M
--
K
L
---
R
---
E
-
S
I
G
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
Y
Q
D
V
S
F
G
-
A
V
N
M
-
K
L
-----------
P
-------------
E
D
E
I
R
K
R
V
----
D
--------
N
A
-----
L
K
R
T
--
G
I
----
E
-------
H
L
K
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
-
V
E
M
Q
K
E
L
G
I
--
T
I
I
I
A
T
H
D
I
---
D
I
V
-
P
L
Y
-
C
----
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
E
K
--
E
V
I
R
K
V
N
--
L
R
L
-------
P
R
I
G
H
L
M
----------
E
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
74.96
40%
-106
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[5-254]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
I
L
K
V
E
E
L
N
Y
N
Y
S
--
D
G
---
T
--
H
A
---
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
-
K
P
S
S
G
R
I
L
F
-
D
N
-
K
P
---
I
DY-
S
--
R
--
K
---
G
---
I
M
--
K
L
---
R
---
E
-
S
I
G
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
Y
Q
D
V
S
F
G
-
A
V
N
M
-
K
L
-----------
P
-------------
E
D
E
I
R
K
R
V
----
D
--------
N
A
-----
L
K
R
T
--
G
I
----
E
-------
H
L
K
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
-
V
E
M
Q
K
E
L
G
I
--
T
I
I
I
A
T
H
D
I
---
D
I
V
P
L
-
Y
-
C
----
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
E
K
--
E
V
I
R
K
V
N
--
L
R
L
-------
P
R
I
G
H
L
M
----------
E
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
122
Fugue
74.37
30%
-106
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
R
--
T
I
--
Q
A
---
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
-
R
P
T
E
G
S
V
L
V
-
D
G
-
Q
E
---
L
TTL
S
--
E
--
S
---
E
---
L
T
--
K
A
---
R
---
R
-
Q
I
G
M
I
F
Q
H
F
-
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
-
L
E
L
D
-
N
T
-----------
P
-------------
K
D
E
V
K
R
R
V
----
T
--------
E
L
-----
L
S
L
V
--
G
L
----
G
-------
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
-
K
D
I
N
R
R
L
G
L
--
T
I
L
L
I
T
H
E
M
---
D
V
V
-
K
-
R
I
C
----
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
KT
P
L
A
Q
K
F
I
--
Q
S
T
LHLDIPE
D
Y
Q
E
R
L
Q
----------
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
TGQS
V
D
A
--------
P
L
L
S
E
T
A
R
R
F
N
V
N
NNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
73.92
33%
-104
- C1 -
3TUI
1
METN_ECOLI
C:
[23-254]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
TR
T
I
--
Q
A
---
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
-
R
P
T
E
G
S
V
L
V
-
D
G
-
Q
E
---
L
---
T
--
T
--
L
---
S
ESE
L
T
--
K
A
---
R
---
R
-
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
P
-
L
E
L
D
-
N
T
-----------
P
-------------
K
D
E
V
K
R
R
V
----
T
--------
E
L
-----
L
S
L
V
--
G
L
----
G
-------
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
-
K
D
I
N
R
R
L
G
L
--
T
I
L
L
I
T
H
E
M
---
D
V
V
-
K
R
I
-
C
----
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119
HHSearch
72.50
32%
-103
* C1 *
2OLJ
4
?
A:
[22-250]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
--
S
----
L
--
E
V
---
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
-
D
F
D
E
G
E
I
I
I
-
D
G
-
I
N
---
L
---
K
--
A
KD
T
---
N
---
L
N
--
K
V
---
R
---
E
-
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M
K
V
R
K
W
-----------
P
-------------
R
E
K
A
E
A
K
A
----
M
--------
E
L
-----
L
D
K
V
--
G
L
----
K
-------
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
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P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
-
K
Q
L
A
N
-
E
G
M
--
T
M
V
V
V
T
H
E
M
---
G
F
A
-
R
E
V
-
G
----
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129
Fugue
70.45
28%
-84
- C1 -
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
LPTGQNYT
K
T
D
F
E
H
D
V
M
N
V
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
L
R
R
E
F
V
K
S
I
L
R
QE
I
S
W
F
D
T
N
HSGT
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
GD
K
I
G
M
A
F
Q
Y
L
S
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F
I
T
G
F
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V
A
F
T
H
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W
Q
L
T
L
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M
L
A
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T
P
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F
A
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L
NG
L
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Y
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L
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K
A
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V
L
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F
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L
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L
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LDRKPVIDSS
S
K
A
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R
KDM
K
I
K
G
D
I
T
V
E
N
V
H
F
T
Y
P
--
S
R
--
P
D
--
V
P
I--
L
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
-
D
V
L
K
G
K
I
T
I
-
D
G
-
V
D
---
V
---
R
--
D
--
I
---
N
---
L
E
--
F
L
---
R
---
K
-
N
V
A
V
V
S
Q
E
P
--
A
L
F
N
C
T
I
E
E
N
I
S
L
G
-
K
E
---
G
I
-----------
T
-------------
R
E
E
M
V
A
A
C
----
K
--------
M
A
-----
N
A
E
K
--
F
I
----
K
T
L
PNGYN
T
L
V
G
D
R
G
T
Q
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
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S
E
G
I
V
Q
Q
A
L
-
D
K
A
A
K
G
R
----
T
T
I
I
I
A
H
R
L
---
S
T
I
-
R
-
N
-
A
----
D
L
I
I
S
C
K
N
G
Q
V
V
E
V
G
D
H
R
A
L
M
A
Q
Q
--
G
L
Y
Y
D
L
V
--
T
A
Q
-------
T
F
T
D
A
V
D
----------
S
A
A
--
E
G
E
R
I
G
K
D
A
L
----
S
R
L
--------
K
Q
-----
E
L
E
E
N
N
AQKTN
L
F
E
I
L
Y
H
A
RPH
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
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A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
12
PsiBlast_PDB
70.39
32%
-102
- C1 -
2IT1
-
?
A:
[4-259]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
K
K
F
G
--
N
F
--
T
----
A
---
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
-
K
P
T
S
G
K
I
-------
Y
---
F
---
D
--
E
--
K
---
D
---
V
T
--
E
L
---
P
PKD
R
-
N
V
G
L
V
F
Q
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
E
L
R
-
K
A
-----------
P
-------------
R
E
E
I
D
K
K
V
----
R
--------
E
V
-----
A
K
M
L
--
H
I
----
D
-------
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
-
K
R
L
Q
K
E
L
G
I
--
T
T
V
Y
V
T
H
D
Q
---
A
E
A
-
L
A
M
-
A
----
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
--
K
-
Y
K
F
V
G
G
F
L
G
N
-------
P
P
M
---------------
N
F
V
E
A
K
V
E
D
G
K
L
V
I
----
T
E
K
--------
S
K
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
69.83
32%
-105
- C1 -
2IT1
1
?
B:
[4-259]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
K
K
F
G
--
N
F
--
T
----
A
---
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
-
K
P
T
S
G
K
I
-------
Y
---
F
---
D
--
E
--
K
---
D
---
V
T
--
E
L
---
P
PKD
R
-
N
V
G
L
V
F
Q
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
E
L
R
-
K
A
-----------
P
-------------
R
E
E
I
D
K
K
V
----
R
--------
E
V
-----
A
K
M
L
--
H
I
----
D
-------
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
-
K
R
L
Q
K
E
L
G
I
--
T
T
V
Y
V
T
H
D
Q
---
A
E
A
-
L
A
M
-
A
----
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
--
K
-
Y
K
F
V
G
G
F
L
G
N
-------
P
P
M
---------------
N
F
V
E
A
K
V
E
D
G
K
L
V
I
----
T
E
K
--------
S
K
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124
Fugue
69.36
26%
-96
- C1 -
1OXS
23
?
C:
[1-352]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
R
I
I
V
K
N
V
S
K
V
F
K
--
K
G
--
K
V
--
V
A
---
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
-
V
P
S
T
G
E
L
Y
F
-
D
D
-
R
L
---
V
---
A
--
S
--
N
---
G
---
K
L
--
I
V
PPE
D
---
R
-
K
I
G
M
V
F
Q
T
W
-
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
P
-
L
T
N
M
-
K
M
-----------
S
-------------
K
E
E
I
R
K
R
V
----
E
--------
E
V
-----
A
K
I
L
--
D
I
----
H
-------
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
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P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
-
K
E
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Q
S
R
L
G
V
--
T
L
L
V
V
S
H
D
P
---
A
D
I
-
F
-
A
I
A
----
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
--
V
S
-
I
Q
V
A
--
S
L
I
-------
G
E
I
N
E
L
E
----------
G
K
V
T
N
E
G
V
V
I
G
S
L
R
F
----
P
V
S
VSSDRAII
G
I
R
P
E
D
V
K
L
S
K
D
V
IKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
HHSearch
68.66
38%
-92
- C1 -
1Z47
1
?
A:
[12-237]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
--
G
---
G
A
--
R
S
---
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
-
R
P
T
K
G
D
V
W
I
-
G
G
-
K
R
---
V
---
T
--
D
--
L
---
P
-------
P
Q
---
K
---
R
-
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
R
E
K
-
R
V
-----------
P
-------------
K
D
E
M
D
A
R
V
----
R
--------
E
L
-----
L
R
F
M
--
R
L
----
E
-------
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
-
R
Q
V
H
D
E
M
G
V
--
T
S
V
F
V
T
H
D
Q
---
E
E
A
-
L
E
V
-
A
----
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
68.03
35%
-95
- C1 -
4HLU
3
ECFA1_THEMA
C:
[12-246]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
L
N
S
V
S
F
R
Y
N
--
G
D
------
Y
V
---
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
L
-
A
A
A
G
E
I
F
L
D
-
G
-----------
S
--
P
--
A
---
D
---
P
F
--
L
L
---
R
---
K
-
N
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
G
A
T
V
E
E
D
V
A
F
S
-
L
E
I
M
-
G
L
-----------
D
-------------
E
S
E
M
R
K
R
I
----
K
--------
K
V
-----
L
E
L
V
--
G
L
----
S
-------
G
L
A
A
A
D
P
L
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
V
L
-
E
S
L
K
-
N
E
G
K
--
G
I
I
L
V
T
H
E
L
---
E
Y
L
-
D
-
D
-
M
----
D
F
I
L
H
I
S
N
G
T
I
D
F
C
G
S
W
E
E
F
V
E
R
E
--
F
D
D
V
E
I
-------------
P
F
K
W
K
L
W
----------
K
K
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106
HHSearch
67.95
27%
-94
- C1 -
1OXX
21
?
K:
[1-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
R
I
I
V
K
N
V
S
K
V
F
K
--
K
G
--
K
V
--
V
A
---
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
-
V
P
S
T
G
E
L
Y
F
-
D
D
-
R
L
---
V
---
A
--
S
--
N
GKL
I
---
V
P
--
P
E
---
D
---
R
-
K
I
G
M
V
F
Q
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
P
-
L
T
N
M
-
K
M
-----------
S
-------------
K
E
E
I
R
K
R
V
----
E
--------
E
V
-----
A
K
I
L
--
D
I
----
H
-------
H
V
L
N
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
-
K
E
V
Q
S
R
L
G
V
--
T
L
L
V
V
S
H
D
P
---
A
D
I
-
F
A
I
-
A
----
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
67.03
33%
-105
- C1 -
1XEF
3
D:
[2-231]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GAHDF
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
123
Fugue
67.00
31%
-82
- C1 -
1Z47
1
?
A:
[11-355]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
--
G
G
--
A
R
---
S
---
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
-
R
P
T
K
G
D
V
W
I
-
G
G
-
K
R
---
V
---
T
--
D
--
L
---
P
-------
P
Q
---
K
---
R
-
N
V
G
L
V
F
Q
N
Y
-
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
R
E
K
-
R
V
-----------
P
-------------
K
D
E
M
D
A
R
V
----
R
--------
E
L
-----
L
R
F
M
--
R
L
----
E
-------
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
-
R
Q
V
H
D
E
M
G
V
--
T
S
V
F
V
T
H
D
Q
---
E
E
A
-
L
-
E
V
A
----
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
--
G
T
L
F
V
A
S
F
-
I
G
E
-------
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
D
P
A
V
S
E
G
S
E
V
----
A
V
V
--------
V
R
P
K
D
V
E
L
Q
P
A
S
E
REAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
66.21
33%
-105
- C1 -
2FGJ
2
HLYBP_ECOLX
A:
[8-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GA
H
D
F
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
66.10
33%
-108
- C1 -
1XEF
3
HLYBP_ECOLX
A:
[2-231]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GA
H
D
F
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
65.82
33%
-106
- C1 -
2FGJ
2
HLYBP_ECOLX
B:
[8-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GAHDF
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
65.64
33%
-104
- C1 -
1XEF
3
HLYBP_ECOLX
B:
[2-231]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GAHDF
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
65.49
33%
-107
- C1 -
2FGJ
2
D:
[8-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
--------
L
A
GAHDF
I
S
E
L
RE
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
G
R
-----
T
V
I
I
I
A
A
R
L
---
S
T
V
-
K
-
N
-
A
----
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
--
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
65.16
34%
-105
- C1 -
2FF7
1
A:
[8-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
F
R
N
I
R
F
R
Y
K
--
P
D
--
S
P
--
V
I
---
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
-
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
A
---
L
---
A
--
D
--
P
---
N
----
W
---
L
---
R
---
R
-
Q
V
G
V
V
L
Q
--
D
N
V
L
L
N
R
S
I
I
D
N
I
S
---
L
A
N
P
-
G
M
-----------
S
-------------
V
E
K
V
I
Y
A
A
----
K
L
A
GA
H
D
F
I
S
E
-----
L
R
E
---
G
Y
----
N
-------
T
I
V
G
E
Q
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A