@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2606: (2016-04-05 )
MIEIEKPKIETIEISDDAKYGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSIQIDGALHEFSVIEGVVEDVTTMILNIKKLALKIYSDEEKTLEIDMQGPGVVTAADINYDSDVEILNPDLHIATLSDNAKFHVRLNATRGRGYTPADQNKRENMPIGVLPVDSIFSPVIRVNYQVENTRVGQSTNYDKLTFDVLTDGSISPEEAVSLGAKILSEHLSIFVNLTDEAQKAEIMIEKEESHKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELADKSEDDMMKVRNLGRKSLEEVKVKLADLGLSLRNEN
Atome Classification :
(20 SA)
---.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130-.......140.......150---.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MIEIEKP
K
I
E
T
I
E
ISDDAKY
G
K
F
V
V
E
P
L
E
RGYGT
T
L
G
N
S
L
R
R
I
L
L
SSLPG
A
A
V
T
S
I
Q
IDGA
L
H
E
F
S
V
I
E
G
V
V
E
D
V
T
T
M
I
L
N
I
K
K
L
A
L
K
I
YSDEE
K
T
L
E
I
DMQGP
G
V
V
T
A
A
DINYDSD
V
E
I
LNPD
L
H
I
A
TLSD-N
A
K
F
H
V
R
L
N
ATRGRGYTPAD---QNKRENM
P
I
G
V
L
P
V
D
S
IFSP
V
I
R
V
N
Y
Q
V
E
N
T
RVGQSTNY
D
K
L
T
F
D
V
LTDGSI
S
P
E
E
A
V
S
L
G
A
K
I
L
S
E
H
L
S
I
F
V
NLTDEAQK
A
E
I
M
I
EKE
E
S
H
K
E
K
V
L
E
M
T
I
E
E
LD
L
S
V
R
S
Y
N
C
L
K
R
AG
I
N
T
V
Q
E
L
ADKS
E
D
D
M
M
K
V
R
N
L
G
R
K
S
L
E
E
V
K
V
K
L
A
DL
G
L
SL--RNEN
4
PsiBlast_PDB
87.73
45%
-86
- C3 -
4JK2
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
19
PsiBlast_PDB
87.71
45%
-92
- C3 -
4ZH4
-
?
A:
[14-326]
------
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
------------------
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
3
PsiBlast_PDB
87.71
45%
-87
- C3 -
4JK1
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
7
PsiBlast_PDB
87.64
45%
-88
- C3 -
4KN4
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
18
PsiBlast_PDB
87.56
45%
-92
- C3 -
4ZH3
-
?
A:
[14-326]
------
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
------------------
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
17
PsiBlast_PDB
87.35
45%
-90
- C3 -
4ZH2
-
?
A:
[14-326]
------
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
------------------
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
8
PsiBlast_PDB
87.16
45%
-88
- C3 -
4KN7
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
6
PsiBlast_PDB
86.72
45%
-88
- C3 -
4KMU
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
13
PsiBlast_PDB
86.03
45%
-93
- C3 -
4YG2
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
15
PsiBlast_PDB
85.95
45%
-95
- C3 -
4MEX
-
RPOA_ECOLI
A:
[13-326]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TR---------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
----------------
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
16
PsiBlast_PDB
85.82
45%
-97
- C3 -
4MEY
-
RPOA_ECOLI
A:
[13-326]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TR---------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
----------------
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
GM
R
L
E
N
10
PsiBlast_PDB
85.66
45%
-92
- C3 -
4YFK
-
RPOA_ECO24
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
14
PsiBlast_PDB
83.23
45%
-94
- C3 -
5BYH
-
?
A:
[10-320]
--------
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
----------------
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
1
PsiBlast_PDB
80.97
45%
-88
- C3 -
3IYD
-
RPOA_ECOLI
A:
[7-320]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI-----
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
---
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
11
PsiBlast_PDB
72.41
45%
-88
- C3 -
4YFN
-
RPOA_ECO24
A:
[7-235]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
----------------------------------------------------------------------------------------
12
PsiBlast_PDB
70.84
45%
-87
- C3 -
4YFX
-
RPOA_ECO24
A:
[7-235]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
TRI
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
----------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.68
45%
-86
- C3 -
4JKR
1
?
A:
[7-232]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
-------------------------------------------------------------------------------------------
83
Fugue
70.66
49%
-87
- C3 -
1BDF
-
RPOA_ECOLI
A:
[2-232]
QGS
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
-
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
A
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
---
T
R
I
E
R
--
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
-------------------------------------------------------------------------------------------
59
HHSearch
69.59
48%
-87
- C3 -
1BDF
-
RPOA_ECOLI
A:
[6-232]
----
T
E
F
L
K
P
R
L
V
-
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
A
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
---
T
R
I
--
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
-------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.21
45%
-84
- C3 -
4S20
-
?
A:
[7-232]
-----
E
F
L
K
P
R
L
V
D
I
E
-
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
-------------------------------------------------------------------------------------------