@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2642: (2016-04-05 )
VIRFFKIVTPILLSISLVACSSASGKTEKITAPIEKDRNLSMVVTTDVHYFAPSLTDNGKAFEKYVAAGDGKQLAYSDEITDAFLADVESKKTDVLIISGDLTNNGEKTSHEELAKKLTQVEKNGTQVFVVPGNHDINNPWARKFEKDKQLPTDTISPTDFSKIYGDFGYEDAISSDEFSLSYLAAPSSKVWLLMLDTAIYKTNMQQGNPTTEGGLTAGTLDWIKESSALAKKNGAKLIPVLHHNLTDHNDVIQKGYTINYNQQVIDALTEGAMDFSLSGHIHTQNIRSAKSTDGKEITDIVTNALSVFPHKYGNITYSAKNKNFTYQSQKLDMEAWAKAQGSTDENLLNFDQFDYETFYNSGYDKAMMDLMTDESYDKYNQADKEKMADTMGLNNMYFFAGTAPPKSDGMALWDSAPNSFLKDYVLSSSNPPKKSNDYYVSP
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90-...--......100--......-----.----110-.-...----....-.120---------------..-.....130.......140.......150.......160...-....170---...-....180....----.---.-----.190.......200--------------.....----------------------------------..210.......220------.......230.-......240.......250.......260.......270.-.......---280.......--------290.----------------......300....--------------.--------.----------------.-----310.......320.......330.-----......340.......350.......360.......370.......380.......390.......400.....-.-.410.......420.......430.......440.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VI
R
F
F
K
I
V
T
P
I
L
L
S
I
S
L
V
ACSSASGKTE
K
I
TAPIEKDR
N
L
S
M
V
V
TTD
V
H
Y
FAPSLTDN
G
K
A
F
E
K
Y
V
AAGDG
K
Q
L
AYSDE
I
T
D
A
F
L
A
DVES--KKT--
D
V
L
I
I
SGDL--TNNGEK-----T----
S
---
H
-
E
E
L
----
A
K
K
L
-
T
Q
VE---------------KN-G
T
Q
V
F
V
VPGNHDIN
N
P
W
A
R
K
F
E
KDKQLPTDTISP
T
D
F
S
K
I
Y
-GDFGYED---AIS-SDE
F
S
L
S
Y
LAA----P---S-----
S
K
V
W
L
L
M
LDT
A
I
Y
K--------------TNMQQ----------------------------------GNPTTEGGLTAG
T
L
D
------
W
I
K
E
S
S
A
L
AKK-NG
A
K
L
I
P
V
LHHNLTD
H
N
D
V
I
QKG
Y
T
INY
N
Q
Q
V
I
D
A
L
T
E-G-AM
D
F
SLS---G
H
I
H
T
QNIRS--------AKST----------------D
G
K
E
I
T
D
I
V
T
N
A
L
--------------
S
--------V----------------F-----PHKYG
N
I
T
Y
S
AKNKN
F
T
Y
Q
S
QKL
D
-----
M
E
A
W
A
KAQGSTDENLLN
F
D
Q
F
D
Y
E
T
F
YNSG
Y
D
K
A
M
M
D
L
MTDESYDKYN
Q
A
D
K
E
K
M
A
D
TMGLNN
M
Y
F
F
AGTAPPK-S-DG
M
A
LWDSA
P
N
S
F
L
K
D
Y
V
LSSSNPPKKSNDYYVSP
21
HHSearch
96.79
100%
-58
- C2 -
2XMO
4
?
A:
[33-443]
--------------------------------
P
I
E
K
D
R
N
L
S
M
V
V
T
T
D
V
H
Y
F
A
P
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D
N
G
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A
F
E
K
Y
V
A
A
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D
G
K
Q
L
A
Y
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D
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A
F
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A
D
V
E
S
--
K
K
T
--
D
V
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I
I
S
G
D
L
--
T
N
N
G
E
K
-----
T
----
S
---
H
-
E
E
L
----
A
K
K
L
-
T
Q
V
E
---------------
K
N
-
G
T
Q
V
F
V
V
P
G
N
H
D
I
N
N
P
W
A
R
K
F
E
K
D
K
Q
L
P
T
D
T
I
S
P
T
D
F
S
K
I
Y
-
S
D
F
G
Y
E
D
---
A
I
S
-
S
D
E
F
S
L
S
Y
L
A
A
----
P
---
S
-----
S
K
V
W
L
L
M
L
D
T
A
I
Y
K
--------------
T
N
M
Q
Q
----------------------------------
G
N
P
T
T
E
G
G
L
T
A
G
T
L
D
------
W
I
K
E
S
S
A
L
A
K
K
-
N
G
A
K
L
I
P
V
L
H
H
N
L
T
D
H
N
D
V
--
K
G
Y
T
I
N
Y
N
Q
Q
V
I
D
A
L
T
E
-
G
-
A
M
D
F
S
L
S
---
G
H
I
H
T
Q
N
I
R
S
--------
A
K
S
T
----------------
D
G
K
E
I
T
D
I
V
T
N
A
L
--------------
S
--------
V
----------------
F
-----
P
H
K
Y
G
N
I
T
Y
S
A
K
N
K
N
F
T
Y
Q
S
Q
K
L
D
-----
M
E
A
W
A
K
A
Q
G
S
T
D
E
N
L
L
N
F
D
Q
F
D
Y
E
T
F
Y
N
S
G
Y
D
K
A
M
M
D
L
M
T
D
E
S
Y
D
K
Y
N
Q
A
D
K
E
K
M
A
D
T
M
G
L
N
N
M
Y
F
F
A
G
T
A
P
P
K
-
S
-
D
G
M
A
L
W
D
S
A
P
N
S
F
L
K
D
Y
V
L
S
S
S
N
P
P
K
K
S
N
D
Y
Y
V
S
P
1
PsiBlast_PDB
96.58
99%
-58
- C2 -
2XMO
4
?
A:
[33-443]
--------------------------------
P
I
E
K
D
R
N
L
S
M
V
V
T
T
D
V
H
Y
F
A
P
S
L
T
D
N
G
K
A
F
E
K
Y
V
A
A
G
D
G
K
Q
L
A
Y
S
D
E
I
T
D
A
F
L
A
D
V
E
S
--
K
K
T
--
D
V
L
I
I
S
G
D
L
--
T
N
N
G
E
K
-----
T
----
S
---
H
-
E
E
L
----
A
K
K
L
-
T
Q
V
E
---------------
K
N
-
G
T
Q
V
F
V
V
P
G
N
H
D
I
N
N
P
W
A
R
K
F
E
K
D
K
Q
L
P
T
D
T
I
S
P
T
D
F
S
K
I
Y
-
S
D
F
G
Y
E
D
---
A
I
S
-
S
D
E
F
S
L
S
Y
L
A
A
----
P
---
S
-----
S
K
V
W
L
L
M
L
D
T
A
I
Y
K
--------------
T
N
M
Q
Q
----------------------------------
G
N
P
T
T
E
G
G
L
T
A
G
T
L
D
------
W
I
K
E
S
S
A
L
A
K
K
-
N
G
A
K
L
I
P
V
L
H
H
N
L
T
D
H
N
D
V
--
K
G
Y
T
I
N
Y
N
Q
Q
V
I
D
A
L
T
E
-
G
-
A
M
D
F
S
L
S
---
G
H
I
H
T
Q
N
I
R
S
--------
A
K
S
T
----------------
D
G
K
E
I
T
D
I
V
T
N
A
L
--------------
S
--------
V
----------------
F
-----
P
H
K
Y
G
N
I
T
Y
S
A
K
N
K
N
F
T
Y
Q
S
Q
K
L
D
-----
M
E
A
W
A
K
A
Q
G
S
T
D
E
N
L
L
N
F
D
Q
F
D
Y
E
T
F
Y
N
S
G
Y
D
K
A
M
M
D
L
M
T
D
E
S
Y
D
K
Y
N
Q
A
D
K
E
K
M
A
D
T
M
G
L
N
N
M
Y
F
F
A
G
T
A
P
P
K
-
S
-
D
G
M
A
L
W
D
S
A
P
N
S
F
L
K
D
Y
V
L
S
S
S
N
P
P
K
K
S
N
D
Y
Y
V
S
P
41
Fugue
96.51
99%
-56
- C2 -
2XMO
4
?
A:
[33-443]
--------------------------------
P
I
E
K
D
R
N
L
S
M
V
V
T
T
D
V
H
Y
F
A
P
S
L
T
D
N
G
K
A
F
E
K
Y
V
A
A
G
D
G
K
Q
L
A
Y
S
D
E
I
T
D
A
F
L
A
D
V
E
S
--
K
K
T
--
D
V
L
I
I
S
G
D
L
--
T
N
N
G
E
K
-----
T
----
S
---
H
-
E
E
L
----
A
K
K
L
-
T
Q
V
E
---------------
K
N
-
G
T
Q
V
F
V
V
P
G
N
H
D
I
N
N
P
W
A
R
K
F
E
K
D
K
Q
L
P
T
D
T
I
S
P
T
D
F
S
K
I
Y
-
S
D
F
G
Y
E
D
---
A
I
S
-
S
D
E
F
S
L
S
Y
L
A
A
----
P
---
S
-----
S
K
V
W
L
L
M
L
D
T
A
I
Y
K
--------------
T
N
M
Q
Q
----------------------------------
G
N
P
T
T
E
G
G
L
T
A
G
T
L
D
------
W
I
K
E
S
S
A
L
A
K
K
-
N
G
A
K
L
I
P
V
L
H
H
N
L
T
D
H
N
D
--
V
K
G
Y
T
I
N
Y
N
Q
Q
V
I
D
A
L
T
E
-
G
-
A
M
D
F
S
L
S
---
G
H
I
H
T
Q
N
I
R
S
--------
A
K
S
T
----------------
D
G
K
E
I
T
D
I
V
T
N
A
L
--------------
S
--------
V
----------------
F
-----
P
H
K
Y
G
N
I
T
Y
S
A
K
N
K
N
F
T
Y
Q
S
Q
K
L
D
-----
M
E
A
W
A
K
A
Q
G
S
T
D
E
N
L
L
N
F
D
Q
F
D
Y
E
T
F
Y
N
S
G
Y
D
K
A
M
M
D
L
M
T
D
E
S
Y
D
K
Y
N
Q
A
D
K
E
K
M
A
D
T
M
G
L
N
N
M
Y
F
F
A
G
T
A
P
P
K
-
S
-
D
G
M
A
L
W
D
S
A
P
N
S
F
L
K
D
Y
V
L
S
S
S
N
P
P
K
K
S
N
D
Y
Y
V
S
P
24
HHSearch
50.68
14%
-68
- C2 -
3D03
2
?
A:
[1-245]
---------------------------------------
M
L
L
A
H
I
S
D
T
H
F
R
S
R
G
E
K
L
--------------
Y
G
F
I
D
V
N
A
A
N
A
D
V
V
S
Q
L
N
A
LR
E
R
P
--
D
A
V
V
V
S
G
D
I
--
V
N
C
G
R
P
-----
E
----
E
---
Y
-
Q
V
A
----
R
Q
I
L
-
G
S
L
-------------------
N
Y
P
L
Y
L
I
P
G
N
H
D
D
K
A
L
F
L
E
Y
----------------
L
Q
P
L
C
-
P
Q
L
G
S
----------
D
A
N
N
M
R
C
A
V
D
----
D
---------
F
A
T
R
L
L
F
I
D
S
S
R
A
G
--------------
T
------------------------------------------
S
K
G
W
L
T
D
E
T
I
S
------
W
L
E
A
Q
L
F
E
G
---
G
D
K
P
A
T
I
F
M
H
H
P
P
L
P
L
G
N
A
Q
M
D
P
I
A
C
E
N
G
H
R
L
L
A
L
V
E
R
-
F
P
S
L
T
R
I
F
C
---
G
H
N
H
S
L
T
M
T
Q
--------
Y
R
-------------------
Q
A
L
I
-
S
T
L
P
G
T
V
H
Q
V
P
Y
C
HADTDPYY
D
--------
L
----------------
S
-----
P
A
S
C
L
M
H
R
Q
V
G
E
---------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
50.15
17%
-64
- C2 -
3IB7
7
CPDA_MYCTU
A:
[21-279]
----------------------------------
H
P
R
P
D
Y
V
L
L
H
I
S
D
T
H
L
I
G
G
D
R
R
L
Y
G
--------------
A
V
D
A
D
D
R
L
G
E
L
L
E
Q
L
N
Q
S
G
L
R
P
--
D
A
I
V
F
T
G
D
L
--
A
D
K
G
E
P
-----
A
----
A
---
Y
-
R
K
L
----
R
G
L
V
-
E
P
F
A
A
--------------
Q
L
-
G
A
E
L
V
W
V
M
G
N
H
D
D
R
A
E
L
R
K
----------------
F
L
L
D
E
A
-
P
S
--------------
M
A
P
L
D
R
V
C
M
----
I
---------
D
G
L
R
I
I
V
L
D
T
S
V
P
G
--------------
H
------------------------------------------
H
H
G
E
I
R
A
S
Q
L
G
------
W
L
A
E
E
L
A
T
P
A
---
P
D
G
T
I
L
A
L
H
H
P
P
I
P
S
V
L
D
M
A
V
T
V
E
L
R
D
Q
A
A
L
G
R
V
L
R
G
-
T
-
D
V
R
A
I
L
A
---
G
H
L
H
Y
S
T
N
A
T
--------
F
---------------------
V
G
I
P
V
S
V
A
S
A
T
--------------
C
--------
Y
T
Q
D
LTVAAG
G
T
R
G
R
D-
G
-----
A
Q
G
C
N
L
V
H
V
Y
P
D
--
T
V
V
H
S
V
I
P
L
G
---------------------------------------------------------------------------------------------------------------------
25
HHSearch
49.50
19%
-54
- C2 -
1UTE
4
PPA5_PIG
A:
[3-241]
-----------------------------------
P
T
P
I
L
R
F
V
A
V
G
D
W
G
G
V
P
N
A
P
F
H
----------------
T
A
R
E
M
A
N
A
K
A
I
A
T
T
V
K
T
--
L
G
A
--
D
F
I
L
S
L
G
D
N
--
F
Y
F
T
G
V
H----
D
AKDK
R
---
F
Q
E
T
F
----
E
D
V
F
-
S
D
P
S
---------------
L
R
-
N
V
P
W
H
V
L
A
G
N
H
D
H
L
G
N
V
S
A
Q
I
--------------
A
Y
S
K
I
S
-
K
R
W
N
F
------------
P
S
P
Y
Y
R
L
R
----
F
---
K
IPRSN
V
S
V
A
I
F
M
L
D
T
V
T
L
C
--------------
G
N
S
D
D
FVSQQ-----------------------------
P
E
R
P
R
N
L
A
L
A
R
T
Q
L
A
------
W
I
K
K
Q
L
A
A
A
---
K
E
D
Y
V
L
V
A
G
H
Y
P
V
W
S
I
A
E
H
G
---
P
T
H
C
L
V
K
Q
L
L
P
L
L
T
T
-
H
-
K
V
T
A
Y
L
C
---
G
H
D
H
N
L
Q
Y
L
Q
--------
D
E
--------------------
N
G
L
G
F
V
L
S
G
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
48.31
13%
-39
* C2 *
2NXF
6
ADPRM_DANRE
A:
[3-304]
------------------------------------
D
P
V
F
T
F
G
L
I
A
D
V
Q
Y
A
D
I
E
D
---
G
E
N
Y
L
R
T
----
R
R
R
Y
Y
R
G
S
A
D
L
L
R
D
A
V
L
Q
W
R
R
--
E
R
V
--
Q
C
V
V
Q
L
G
D
I
--
I
D
G
H
N
R
R
R
D--
A
----
S
---
D
-
R
A
L
----
D
T
V
M
-
A
E
L
D
---------------
A
C
-
S
V
D
V
H
H
V
W
G
N
H
E
F
Y
N
F
S
R
P
S
L
L
S
S
-----------
R
L
N
S
-
A
-
Q
---------
G
S
D
L
I
G
D
D
I
Y
A
Y
E
F
S
----
P
---
A
-----
P
N
F
R
F
V
L
L
D
A
Y
D
L
S
--------------
V
I
G
R
E
EES
E
K
H
T
H
S
W
R
I
L
T
Q
H
N
HNLQDLNLPPVSVGLEQ
R
F
V
K
F
N
G
G
F
S
E
Q
Q
L
Q
------
W
L
D
A
V
L
T
L
S
D
H
-
K
Q
E
R
V
L
I
F
S
H
L
P
V
H
P
C
A
A
D
--
P
I
C
L
A
W
N
H
E
A
V
L
S
V
L
R
S
-
H
Q
S
V
L
C
F
I
A
---
G
H
D
H
D
G
G
R
C
T
--------
D
S
--------------------
S
G
A
Q
H
I
T
L
E
G
V
--------------
I
--------
E
----------------
T
PPH--
S
H
A
F
A
T
A
Y
L
Y
E
D
---------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
47.51
15%
-55
- C2 -
3AV0
4
MRE11_METJA
A:
[18-252]
------------------------------------
G
S
H
M
M
F
V
H
I
A
D
N
H
L
G
Y
R
Q
Y
N
L
-------------
D
D
R
E
K
D
I
Y
D
S
F
K
L
C
I
K
K
I
L
E
--
I
K
P
--
D
V
V
L
H
S
G
D
L
--
F
N
D
L
R
P
-----
P
V
K
--
A
---
L
-
R
I
A
----
M
Q
A
F
-
K
K
L
H
---------------
E
N
-
N
I
K
V
Y
I
V
A
G
N
H
E
M
P
R
R
L
G
E
E
---------------
S
P
L
A
L
L
-
K
D
Y
V
K
---------
I
L
D
G
--
K
D
V
I
N
----
V
---
N
G----
E
E
I
F
I
C
G
T
Y
-------------------------------------------------------------
Y
H
K
K
S
K
R
E
E
M
L
D
------
K
L
K
N
F
E
S
E
A
K
--
N
Y
K
K
K
I
L
M
L
H
Q
G
I
N
P
Y
I
P
L
---------
D
Y
E
-
L
E
H
F
D
L
-
P
-
K
F
S
Y
Y
A
L
---
G
H
I
H
K
R
I
L
E
R
--------
F
N
--------------------
D
G
-
I
L
A
Y
S
G
S
T
--------------
E
--------
I
IYRNE
Y
E
D
Y
K
K
-----
E
-----
G
K
G
F
Y
L
V
D
F
S
G
N
---------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
46.78
13%
-55
- C2 -
1UF3
3
?
A:
[3-225]
------------------------------------
R
T
V
R
Y
I
L
A
T
S
N
P
M
G
D
L
E
--------------------------
A
L
E
K
F
V
K
L
A
P
D
--
T
G
A
--
D
A
I
A
L
I
G
N
L
--
M
P
K
A
A
K
-----
S
----------
R
D
Y
----
A
A
F
F
-
R
I
L
S
---------------
E
A
-
H
L
P
T
A
Y
V
P
G
P
Q
D
A
P
I
W
--
E
Y
L
R
E
A
-------
A
N
---
V
E
L
V
H
-
P
E
M
R
N
-----------
V
H
-
E
T
F
T
F
W
----
R
---------
G
P
Y
L
V
A
G
V
G
G
E
I
A
D
--------------
E
G
-----------------------------------------
E
P
E
E
H
E
A
L
R
Y
P
A
W
V
A
E
Y
R
L
K
A
L
W
E
L
--
K
-
D
-
Y
P
K
I
F
L
F
H
T
M
P
Y
H
K
G
L
------
N
E
Q
G
S
H
E
V
A
H
L
I
K
T
-
H
-
N
P
L
L
V
L
V
A
G
K
G
Q
K
H
E
----
M
--------
L
---------------------
G
A
S
W
V
V
V
P
G
D
L
--------------
S
-------------------------------
E
G
E
Y
S
L
L
D
L
R
A
--
R
K
L
E
T
G
--------------------------------------------------------------------------------------------------------------------------
37
HHSearch
45.99
18%
-53
- C2 -
3THO
6
RAD50_THEMA
B:
[1-251]
---------------------------------------
M
K
I
L
H
T
S
D
W
H
L
G
V
T
S
W
T
S
S
----------
R
P
V
D
R
R
E
E
L
K
K
A
L
D
K
V
V
E
E
A
E
K
--
R
E
V
--
D
L
I
L
L
T
G
D
L
--
L
H
S
R
N
N
-----
P
----
S
V
V
A
L
-
H
D
L
----
L
D
Y
L
-
K
R
M
M
---------------
R
--
T
A
P
V
V
V
L
P
G
N
Q
D
W
K
G
L
K
L
--
F
G
-------------
N
F
V
T
S
I
S
S
D
I
T
F
V
----------
M
S
F
E
P
V
D
V
E
----
A
KR-
G
-----
Q
K
V
R
I
L
P
F
P
Y
P
D
E
S
--------------------------------------------------------
K
N
E
G
D
F
R
F
F
L
E
S
------
R
L
N
K
L
Y
E
E
A
L
K
-
K
E
D
F
A
I
F
M
G
H
F
T
V
E
G
L
A
G
---------
R
E
I
I
I
N
R
A
L
I
P
-
S
-
V
V
D
Y
A
A
L
---
G
H
I
H
S
F
R
E
I
Q
--------
K
--------------------
Q
P
L
T
--
I
Y
P
G
S
L
--------------
I
--------
R
IDFGEEA---------
D
-----
E
K
G
A
V
F
V
E
L
K
R
G
---------------------------------------------------------------------------------------------------------------------------------
42
Fugue
45.54
17%
-43
- C2 -
2HY1
3
CPDA_MYCTU
A:
[12-267]
----------------------------------------------------------
P
R
P
D
Y
V
L
L
H
I
S
D
T
-
H
L
I
D
A
D
D
R
L
G
E
L
L
E
Q
L
N
Q
--
S
G
L
RP
D
A
I
V
F
T
G
D
L
--
A
D
K
G
E
P
-----
A
----
A
---
Y
-
R
K
L
----
R
G
L
V
-
E
P
F
A
---------------
A
Q
L
G
A
E
L
V
W
V
M
G
N
H
D
D
R
A
E
L
R
K
F
L
L
D
E
A
P
S
M
----
A
P
L
D
R
V
C
M
I
-
D
G
---------------------------------------
L
R
I
I
V
L
D
T
S
V
--------------------------------------------------------
P
G
H
H
H
G
E
I
R
A
S
Q
L
G
------
W
L
A
E
--
E
L
A
T
P
-
A
P
D
G
T
I
L
A
L
H
H
P
P
I
P
S
V
L
D
M
A
V
T
V
E
L
R
D
Q
A
A
L
G
R
V
L
R
G
-
T
-
D
V
R
A
I
L
A
---
G
H
L
H
Y
S
T
N
A
T
--------
F
V
G
I
----------------
P
V
S
V
A
S
A
T
C
G
C
N
L
--------------
V
--------
H
----------------
V
-----
Y
P
D
T
V
V
H
S
V
I
P
----------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
45.46
19%
-68
- C2 -
3CK2
5
?
A:
[4-163]
------------------------------------
M
A
K
Q
T
I
I
V
M
S
D
S
H
G
D
S
L
--------------------------
I
V
E
E
V
R
D
R
Y
V
---
G
K
V
--
D
A
V
F
H
N
G
D
S
--
E
L
R
P
D
S
-----
P
------------------------
L
-------------------
W
E
G
I
R
V
V
K
G
N
M
D
F
Y
A
G
Y
--------------------------------------------------------------------------------------------
P
----------------------------------------------------
E
------
R
L
V
T
------
E
-
L
G
S
T
K
I
I
Q
T
H
G
H
L
F
D
I
N
F
---------
N
F
Q
K
L
D
Y
W
A
Q
E
-
E
-
E
A
A
I
C
L
Y
---
G
H
L
H
V
P
S
A
W
L
--------
E
---------------------
G
K
I
L
F
L
N
P
G
S
I
--------------
S
--------
Q
PRGTI-----------
R
-----
E
C
L
Y
A
R
V
E
I
D
D
S
--
Y
F
K
V
D
F
L
T
R
D
---------------------------------------------------------------------------------------------------------------------
38
HHSearch
45.34
14%
-85
- C2 -
1S3L
2
P936_METJA
A:
[26-183]
---------------------------------------
M
K
I
G
I
M
S
D
T
H
D
H
L
P
--------------------------
N
I
R
K
A
I
E
I
F
N
D
--
E
N
V
--
E
T
V
I
H
C
G
D
F
--
V
S
L
F
--------------------
V
----
I
K
E
F
-
E
N
L
-------------------
N
A
N
I
I
A
T
Y
G
N
N
D
G
E
R
C
K
L
K
----------------
E
W
---
L
-
K
-----------------------
D
----
I
---------
N
E
E
N
I
I
--------------------------------------------------------------------------
D
D
------
F
I
S
V
------
E
-
I
D
D
L
K
F
F
I
T
H
G
H
H
Q
S
V
L
---------------
E
M
A
I
K
S
-
G
-
L
Y
D
V
V
I
Y
---
G
H
T
H
E
R
V
F
E
E
--------
V
---------------------
D
D
V
L
V
I
N
P
G
E
C
--------------
C
--------
G
----------------
Y
LTG--
I
P
T
I
G
I
L
D
T
E
K
K
---------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
45.01
14%
-57
- C2 -
2QFP
11
PPAF_PHAVU
A:
[117-324]
------------------------------------
D
V
P
Y
T
F
G
L
I
G
D
L
G
Q
S
F
D
S
N
-----------------------
T
T
L
S
H
Y
--
E
L
S
P
--
K
K
G
--
Q
T
V
L
F
V
G
D
L
--
S
Y
A
D
R
Y
PNHDN
V
----
R
---
W
-
D
T
W
----
G
R
F
T
-
E
R
S
V
----------------
A
-
Y
Q
P
W
I
W
T
A
G
N
H
E
I
E
F
A
P
E
I
N
--
E
----------
T
E
P
F
K
P
F
S
-
Y
R
Y
H
V
P
Y
---
E
A
S
-
Q
S
T
S
P
F
W
Y
S
I
K
----
R
---------
A
S
A
H
I
I
V
L
S
S
Y
S
A
Y
------------------------------------------------------------
G
R
G
T
P
Q
Y
T
------
W
L
K
K
E
L
R
K
V
K
R
S
E
T
P
W
L
I
V
L
M
H
S
P
L
Y
N
S
Y
N
H
H
F
M
-
E
G
E
A
M
R
T
K
F
E
A
W
F
V
K
-
Y
-
K
V
D
V
V
F
A
---
G
H
V
H
A
Y
E
R
S
E
--------
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
44.80
12%
-37
- C2 -
2DXN
2
?
A:
[1-271]
---------------------------------------
M
L
L
A
H
I
S
D
T
H
F
R
S
R
G
E
K
L
Y
G
F
I
--------------
D
V
N
A
A
N
A
D
V
V
S
Q
L
N
A
--
L
R
E
RP
D
A
V
V
V
S
G
D
I
--
V
N
C
G
R
P
-----
E
----
E
---
Y
-
Q
V
A
----
R
Q
I
L
-
G
S
L
N
-------------------
Y
P
L
Y
L
I
P
G
N
H
D
D
K
A
L
F
L
E
Y
L
Q
P
L
C
P
Q
L
G
S
D
A
N
N
M
R
C
A
V
D
D
-
F
A
T
---------------------------------------
R
L
L
F
I
D
S
S
R
--------------------------------------------------------
A
G
T
S
K
G
W
L
T
D
E
T
I
S
------
W
L
E
A
--
Q
L
F
E
G
-
G
D
K
P
A
T
I
F
M
H
H
P
P
L
P
L
G
N
A
Q
M
D
P
I
A
C
E
N
G
H
R
L
L
A
L
V
E
R
F
P
-
S
L
T
R
I
F
C
---
G
H
N
H
S
L
T
M
T
Q
Y
RQAL
I
S
T
L
P
G
T
----------------
V
H
Q
V
P
Y
C
H
E
D
T
D
P
--------------
Y
--------
Y
----------------
D
-----
L
S
P
A
S
C
L
M
H
R
Q
V
G
E
Q
W
V
S
Y
Q
H
S
L
A
H
Y
A
G
P
W
L
Y
D
E
N
I
S
C
P
T
-----------------------------------------------------------------------------------------------------
46
Fugue
44.57
12%
-36
- C2 -
2NXF
6
ADPRM_DANRE
A:
[3-322]
------------------------------------
D
P
V
F
T
F
G
L
I
A
D
V
Q
Y
A
D
I
E
D
G
E
N
Y
L
R
T
R
R
R
-------
Y
Y
R
G
S
A
D
L
L
R
D
A
V
L
Q
W
R
R
--
E
R
V
--
Q
C
V
V
Q
L
G
D
I
ID
G
H
N
R
R
R
-----
D
----
A
---
S
-
D
R
A
----
L
D
T
V
M
A
E
L
D
---------------
A
C
-
S
V
D
V
H
H
V
W
G
N
H
E
F
Y
N
F
S
R
P
S
L
L
S
S
R
L
N
S
A
Q
G
S
D
L
I
G
D
D
I
Y
A
-
Y
E
F
S
P
A
P
N
F
R
F
V
L
-
L
D
A
Y
D
L
S
V
I
G
R
----
E
---
E
-----
E
S
E
K
H
T
H
S
W
R
I
L
T
Q
H
N
HNLQDLNLPPVS
V
G
L
E
Q
----------------------------------
R
F
V
K
F
N
G
G
F
S
E
Q
Q
L
Q
------
W
L
D
A
V
L
T
L
S
D
H
-
K
Q
E
R
V
L
I
F
S
H
L
P
V
--
H
P
C
A
A
D
P
I
C
L
A
W
N
H
E
A
V
L
S
V
L
R
S
H
Q
-
S
V
L
C
F
I
A
---
G
H
D
H
D
G
G
R
C
T
--------
D
S
S
--------------------
G
A
Q
H
I
T
L
E
G
V
--------------
I
--------
E
----------------
T
-----
P
P
H
---------------------------------------------------------------------------------------
S
H
A
F
A
T
A
Y
L
Y
E
D
R
M
V
M
K
G
R
G
R
V
E
D
L
T
I
T
Y
S
---------------------
35
HHSearch
44.56
16%
-41
- C2 -
3T1I
9
MRE11_HUMAN
A:
[28-312]
----------------------------------
D
D
E
N
T
F
K
I
L
V
A
T
D
I
H
L
G
F
M
E
K
D
--------------
A
V
R
G
N
D
T
F
V
T
L
D
E
I
L
R
L
A
Q
E
--
N
E
V
--
D
F
I
L
L
G
G
D
L
--
F
H
E
N
K
P
-----
S
R
K
--
T
---
L
-
H
T
C
----
L
E
L
L
-
R
K
Y
C
MGDRPVQFEILSDQL
N
I
-
S
I
P
V
F
S
I
H
G
N
H
D
D
P
T
G
A
D
A
-
L
C
-----
A
L
D
I
L
S
C
A
G
F
V
N
H
F
-
G
R
S
M
------
S
V
E
-
K
-
I
D
I
S
P
V
L
L
Q
----
K
G--
S
-----
T
K
I
A
L
Y
G
L
G
S
I
P
D
E
--------------
R
------------------------------------------
L
Y
R
M
F
V
N
K
K
V
T
------
M
L
R
P
K
E
D
---
E
-
N
S
W
F
N
L
F
V
I
H
Q
N
R
S
K
H
G
S
---
T
-------
N
F
I
P
E
Q
F
L
D
-
D
-
F
I
D
L
V
I
W
---
G
H
E
H
E
C
K
I
A
P
--------
T
K
N
-----------------
E
Q
Q
L
F
Y
I
S
Q
P
G
S
S
--------------
V
VTSLSPGE
A
----------------
V
-----
K
K
H
V
G
L
L
R
I
K
G
R
---------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
44.36
12%
-46
- C2 -
3TGH
6
?
A:
[2-293]
-------------------------------------
C
Q
L
R
F
A
S
L
G
D
W
G
K
D
T
K
G
----------------------
Q
I
L
N
A
K
Y
F
K
Q
F
I
K
N
--
E
R
V
--
T
F
I
V
S
P
G
S
N
--
F
I
D
G
V
K
-----
G
L---
N
---
D
-
P
A
W
KNLY
E
D
V
Y
-
S
E
E
K
G--------------
D
M
-
Y
M
P
F
F
T
V
L
G
T
R
D
W
T
G
N
Y
N
A
Q
L
L
K
G
Q
G
----------
D
A
T
N
Y
-
P
K
W
I
M
------------
P
N
Y
W
Y
H
Y
F
T
H
F
T
V
SH
K
D
-----
L
A
A
A
F
I
F
I
D
T
W
V
L
S
--------------
S
N
----------------------------------------
F
P
Y
K
K
I
H
E
K
A
W
N
------
D
L
K
S
Q
L
S
V
A
K
K
-
I
A
D
F
I
I
V
V
G
D
Q
P
I
Y
S
S
G
Y
S
R
G
---
S
S
Y
L
A
Y
Y
L
L
P
L
L
K
D
-
A
-
E
V
D
L
Y
I
S
---
G
H
D
N
N
M
E
V
I
E
--------
D
---------------------
N
D
M
A
H
I
T
C
G
S
G
--------------
S
--------
M
S
Q
G
KSGMKNSKSLFFS
S
-----
D
I
G
F
C
V
H
E
L
S
N
N
--
G
I
V
T
K
F
V
S
S
----------------------------------------------------------------------------------------------------------------------
29
HHSearch
43.76
13%
-57
- C2 -
1XZW
7
PPAF1_IPOBA
A:
[124-331]
------------------------------------
D
V
P
Y
V
F
G
L
I
G
D
I
G
Q
T
H
D
S
N
-----------------------
T
T
L
T
H
Y
E
Q
N
--
S
--
A
K
G
--
Q
A
V
L
F
M
G
D
L
--
S
Y
S
N
R
W
PNHDN
N
----
R
---
W
-
D
T
W
----
G
R
F
S
-
E
R
S
V
----------------
A
-
Y
Q
P
W
I
W
T
A
G
N
H
E
I
D
Y
A
P
D
I
G
------------
E
Y
Q
P
F
V
P
F
T
-
N
R
Y
P
T
P
H
---
E
A
S
-
G
S
G
D
P
L
W
Y
A
I
K
----
R
---------
A
S
A
H
I
I
V
L
S
S
Y
S
G
F
------------------------------------------------------------
V
K
Y
S
P
Q
Y
K
------
W
F
T
S
E
L
E
K
V
N
R
S
E
T
P
W
L
I
V
L
V
H
A
P
L
Y
N
S
Y
E
A
H
Y
M
-
E
G
E
A
M
R
A
I
F
E
P
Y
F
V
Y
-
Y
-
K
V
D
I
V
F
S
---
G
H
V
H
S
Y
E
R
S
E
--------
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
43.68
17%
-44
- C2 -
3RQZ
2
?
A:
[2-228]
-------------------------------------
N
A
M
R
I
L
I
I
S
D
V
H
A
N
L
V
--------------------------
A
L
E
A
V
L
S
D
A
G
----
R
V
--
D
D
I
W
S
L
G
D
I
--
V
G
Y
G
P
R
-----
P
----------
R
E
C
----
V
E
L
V
-
R
V
L
--------------------
A
P
N
I
S
V
I
G
N
H
D
W
A
C
I
G
R
L
S
-------------
L
--------
D
--
N
------------------------------------
P
V
A
R
F
A
--
S
-----------------------------------------------------------
Y
W
T
T
M
Q
L
Q
A
E
H
L
Q
------
Y
L
E
S
L
P
N
R
M
I
----
D
G
D
W
T
V
V
H
G
S
P
R
H
P
I
W
E
----
Y
-
I
Y
N
A
R
I
A
A
L
N
F
P
A
-
F
-
D
T
P
L
C
F
V
---
G
H
T
H
V
P
L
Y
I
R
--------
E
D
E
A
L
S
NV
A
P
H
H
P
N
DG
E
V
L
D
V
S
S
G
R
Y
I
I
N
P
G
A
V
--------------
G
--------
Q
----------------
P
RDGDP
R
A
S
Y
A
I
F
E
P
D
A
--
Q
R
V
T
F
H
R
V
E
Y
R
-----
I
A
D
T
Q
A
Q
---------------------------------------------------------------------------------------------------------