@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2653: (2016-04-06 )
MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGYADAQAYDQIDGAPEERERGITISTAHVEYQTDSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKCDMVDDEELLELVEMEIRDLLTEYEFPGDDIPVIKGSALKALQGEADWEAKIDELMEAVDSYIPTPERDTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDEVEVIGIEEESKKVVVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQVLAKPGSITPHTNFKAETYVLTKEEGGRHTPFFNNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNIELAVELIAPIAIEDGTKFSIREGGRTVGAGVVSNISK
Atome Classification :
(60 SA)
.........10........20........30..--------.....--.--------40.--------..-------......----------50........60........--------------70-...--------------.....80........90........100.......110...-------.....120.......130.......140---.......150.......160.......170......-----.180--------.----------.....---...190.......200....-...210......-.220.------...--------...230.......240....---------...250....-------...260.......270.......280-.........290.---...----...300-.......310...--....320.........330.......-------340.------......350.......360.......370..------.....380---........390...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAKEKFDRSKP
H
V
NI
G
T
I
GHVDHG
K
T
T
L
T
A
A
I
T
--------
T
V
L
AK--K--------G-Y--------AD-------
A
Q
A
Y
DQ----------IDGA
P
E
E
RER
G
I
T
I
S
T
A
H
V
E
--------------
Y
Q-TDS--------------
R
H
Y
A
HVDCPG
H
A
D
Y
V
K
N
M
I
TGAAQMD
G
A
I
L
V
V
SAADG-PMP-------Q
T
R
E
H
I
L
L
SRQVGV
P
Y
I
V
V
F
MNKCDMV
D
---
D
E
E
L
L
E
L
V
E
M
E
I
R
D
L
L
T
E
YEFPGDDIPVIKG
S
A
L
K
A
-----LQ----------G----------EAD
W
E
---
A
K
I
D
E
L
M
E
A
V
D
S
YIPTPERD-TDKP
F
M
M
P
V
E
D
V
-FSITG------R
G
T
--------
V
ATGRVERG
Q
V
KVGD
E
V
E
V
I
---------
G
IEEES
K
K
V
V
-------
V
T
G
V
E
M
F
R
K
L
L
D
Y
A
EAG
D
N
I
G
A
L
L
---
R
G
V
A
R
E
D
I
QRG
Q
V
---LAK----PGSITP-HTNFK
A
E
T
Y
V
L
T
K--EEGGR--HTPFFNNY
R
P
Q
F
Y
F
R
TTDV-------
T
G
I
V
------TLPEG
T
E
M
VMPGDNI
E
L
A
V
E
L
I
A
P
I
A
IEDG
T
------
K
F
S
IREG----
G
R
T
V
G
A
G
V
V
SNISK
20
PsiBlast_PDB
96.08
75%
-93
- C3 -
4G5G
5
EFTU1_ECOLI
A:
[4-392]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
18
PsiBlast_PDB
96.06
75%
-97
- C3 -
3U6K
3
EFTU1_ECOLI
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
47
PsiBlast_CBE
95.74
74%
-94
- C3 -
1D8T
22
EFTU1_ECOLI
A:
[3-391]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
46
PsiBlast_CBE
95.54
74%
-100
- C3 -
1D8T
6
EFTU1_ECOLI
B:
[9-391]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
28
PsiBlast_CBE
95.45
75%
-93
- C3 -
3U6K
3
?
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
41
PsiBlast_CBE
95.43
74%
-97
- C3 -
1EFC
2
EFTU1_ECOLI
A:
[8-391]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
29
PsiBlast_CBE
95.01
74%
-95
- C3 -
1DG1
2
EFTU2_ECOLI
H:
[10-392]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
30
PsiBlast_CBE
94.94
74%
-98
- C3 -
1DG1
2
EFTU2_ECOLI
G:
[10-392]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
111
HHSearch
94.91
74%
-95
- C3 -
2C78
3
EFTU1_THET8
A:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
-
P
N-------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
----------
Q
M
H
R
NPKTRRG
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
9
PsiBlast_PDB
94.82
72%
-92
- C3 -
1EXM
2
EFTU1_THETH
A:
[3-403]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
F
V
T
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
19
PsiBlast_PDB
94.78
75%
-96
- C3 -
3U2Q
3
?
A:
[7-392]
------
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
---
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
7
PsiBlast_PDB
94.39
72%
-97
- C3 -
2C78
3
EFTU1_THET8
A:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
44
PsiBlast_CBE
94.35
74%
-94
- C3 -
2FX3
2
EFTU1_ECOLI
A:
[7-391]
-------
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
34
PsiBlast_CBE
94.30
74%
-106
- C3 -
4PC3
2
EFTU1_ECOLI
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
-------------------------------
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
17
PsiBlast_PDB
94.27
72%
-93
- C3 -
4LC0
10
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
14
PsiBlast_PDB
94.17
72%
-93
- C3 -
4LBW
11
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
1
PsiBlast_PDB
94.05
72%
-94
* C3 *
1EFT
2
EFTU_THEAQ
A:
[1-403]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
F
V
T
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
E
M
H
K
NPKTKR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
13
PsiBlast_PDB
93.99
72%
-92
- C3 -
4LBV
12
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
8
PsiBlast_PDB
93.98
72%
-94
- C3 -
4H9G
12
EFTU1_THETH
A:
[2-403]
--
K
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
35
PsiBlast_CBE
93.96
74%
-103
- C3 -
4PC2
3
?
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
--------------------
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
40
PsiBlast_CBE
93.94
74%
-94
- C3 -
1EFC
2
EFTU1_ECOLI
B:
[8-391]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
16
PsiBlast_PDB
93.75
72%
-89
- C3 -
4LBZ
10
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
11
PsiBlast_PDB
93.68
72%
-95
- C3 -
2C77
4
EFTU2_THET8
A:
[2-403]
--
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
T
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
15
PsiBlast_PDB
93.59
72%
-92
- C3 -
4LBY
9
EFTU1_THETH
A:
[4-402]
-----
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
37
PsiBlast_CBE
93.36
75%
-91
- C3 -
1OB2
4
EFTU2_ECOLI
A:
[1-391]
-
A
K
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
A
-------
A
R
A
F
D
Q
----------
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
4
PsiBlast_PDB
93.02
72%
-92
- C3 -
1B23
5
EFTU_THEAQ
P:
[1-403]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
EMHKNPKTKR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
3
PsiBlast_PDB
92.51
72%
-99
- C3 -
1TUI
2
EFTU_THEAQ
A:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
E
M
H
K
NPKTKR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
38
PsiBlast_CBE
92.50
74%
-95
- C3 -
2BVN
3
EFTU2_ECOLI
B:
[6-391]
------
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
-----------------------------------------
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
39
PsiBlast_CBE
92.49
74%
-95
- C3 -
2BVN
3
EFTU2_ECOLI
A:
[9-391]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
------------------------------
E
K
A
R
G
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
52
PsiBlast_CBE
92.46
70%
-98
- C3 -
4IW3
3
EFTU1_PSEPK
B:
[46-431]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
R
V
C
S
E
--
V
--------
F
-
G
--------
S
-------------
K
----------
I
D
S
A
P
E
E
K
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
N
-
S
T
I
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
-----
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
-----
L
E
----------
G
----------
K
D
D
N
E
MG
T
T
A
V
K
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
-
I
D
Q
P
F
L
M
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
---------
G
L
R
D
T
T
T
T
-
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
---
R
G
T
K
R
D
D
V
E
R
G
Q
V
---
L
V
K
----
P
G
S
V
K
P
-
H
T
K
F
T
A
E
V
Y
V
L
S
K
--
E
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
N
C
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
I
--
22
PsiBlast_CBE
92.32
72%
-96
- C3 -
1TUI
2
EFTU_THEAQ
B:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
EMHKNPKTKR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
21
PsiBlast_CBE
92.07
72%
-98
- C3 -
1TUI
2
EFTU_THEAQ
C:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
Y
V
A
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
EMHKNPKTKR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
10
PsiBlast_PDB
91.98
72%
-100
- C3 -
1HA3
5
EFTU1_THET8
A:
[3-403]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
F
V
T
A
A
--
E
--------
N
P
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
------------
T
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
51
PsiBlast_CBE
91.72
70%
-101
- C3 -
4IW3
4
EFTU1_PSEPK
K:
[46-431]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
R
V
C
S
E
--
V
--------
F
-
G
----------------------
K
----------
I
D
S
A
P
E
E
K
A
-
G
I
T
I
N
T
A
H
V
E
--------------
Y
N
-
S
T
I
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
-----
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
-----
L
E
----------
G
----------
K
D
D
N
E
MGT
T
A
V
K
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
-
I
D
Q
P
F
L
M
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
---------
G
L
R
D
T
T
T
T
-
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
---
R
G
T
K
R
D
D
V
E
R
G
Q
V
---
L
V
K
----
P
G
S
V
K
P
-
H
T
K
F
T
A
E
V
Y
V
L
S
K
--
E
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
N
C
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
I
--
27
PsiBlast_CBE
91.02
72%
-105
- C3 -
1HA3
5
EFTU1_THET8
B:
[3-403]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--------
F
V
T
A
A
--
E
--------
N
P
N
-------------------------------------------------
A
H
V
E
--------------
Y
E
-
T
A
K
--------------
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
---
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
-----
L
E
Q
M
H
R
NPKTRR
G
----------
E
N
E
W
V
---
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
-
V
D
K
P
F
L
M
P
V
E
D
V
-
F
T
I
T
G
------
R
G
T
--------
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
---------
G
L
A
P
E
T
R
K
T
V
-------
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
V
S
R
E
E
V
E
R
G
Q
V
---
L
A
K
----
P
G
S
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
--
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
V
V
------
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
--
31
PsiBlast_CBE
89.20
74%
-100
- C3 -
4PC7
3
EFTU1_ECOLI
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------
G
------------------------------------
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
-
I
D
K
P
F
L
L
P
I
E
D
V
-
F
S
I
S
G
------
R
G
T
--------
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
---------
G
I
-
K
E
T
Q
K
S
T
-------
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
I
K
R
E
E
I
E
R
G
Q
V
---
L
A
K
----
P
G
T
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
--
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
-------
T
G
T
I
------
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
------
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
--
67
PsiBlast_CBE
71.62
36%
-81
- C3 -
3WY9
1
EF1A_PYRHO
A:
[5-426]
---------
K
P
H
V
N
I
V
F
I
G
H
V
D
H
G
K
S
T
T
I
G
R
L
L
Y
D
T
GNIP
E
T
I
I
K
K
F
E---------
S
-
F
--------
K
F
-------
A
W
V
M
D
R
----------
L
K
---
E
E
R
E
R
G
I
T
I
D
V
A
H
T
K
--------------
F
E
-
T
P
H
--------------
R
Y
I
T
I
I
D
A
P
G
H
R
D
F
V
K
N
M
I
T
G
A
S
Q
A
D
A
A
V
L
V
V
A
A
T
D
G
-
V
M
P
-------
Q
T
K
E
H
A
F
L
A
R
T
L
G
I
K
H
I
I
V
T
I
N
K
M
D
M
V
N
Y--
D
Q
K
V
F
E
K
V
K
A
Q
V
E
K
L
L
K
T
L
G
Y
--
K
D
F
P
V
I
P
T
S
A
W
N
G
DNVVK
K
S
----------
D
----------
K
M
P
W
Y
---
N
G
-
P
T
L
I
E
A
L
D
Q
-
I
P
E
P
E
K
P
-
I
D
K
P
L
R
I
P
I
Q
D
V
-
Y
S
I
K
G
------
V
G
T
--------
V
P
V
G
R
V
E
T
G
K
L
K
V
G
D
V
V
-------------
I
F
E
P
A
S
T
I
F
HKPI
Q
G
E
V
K
S
I
E
M
H
H
E
P
L
Q
E
A
L
P
G
D
N
I
G
F
N
V
---
R
G
V
S
K
N
D
I
K
R
G
D
V
---
A
G
H
TDKP
P
T
V
V
R
T
-
K
D
T
F
K
A
Q
I
I
V
L
N
H
--
P
T
A
I
T
VG
Y
S
P
V
L
H
A
H
T
A
Q
I
P
V
R
F
E
Q
I
-------
L
A
K
V
D
PRTGN
I
V
E
E
N
P
Q
F
I
K
T
G
D
S
A
I
V
V
L
R
P
M
K
P
V
V
L
E
P
V
K
EIPQLG
R
F
A
I
R
D
M
----
G
M
T
I
A
A
G
M
V
I
S
I
Q
K
65
PsiBlast_CBE
71.26
36%
-81
- C3 -
3WYA
1
EF1A_PYRHO
A:
[5-426]
---------
K
P
H
V
N
I
V
F
I
G
H
V
D
H
G
K
S
T
T
I
G
R
L
L
Y
D
T
GNIP----------------------------
K
F
-------
A
W
V
M
D
R
----------
L
K
---
E
E
----------
H
T
K
--------------
F
E
-
T
P
H
--------------
R
Y
I
T
I
I
D
A
P
G
H
R
D
F
V
K
N
M
I
T
G
A
S
Q
A
D
A
A
V
L
V
V
A
A
T
D
G
-
V
M
P
-------
Q
T
K
E
H
A
F
L
A
R
T
L
G
I
K
H
I
I
V
T
I
N
K
M
D
M
V
N
Y--
D
Q
K
V
F
E
K
V
K
A
Q
V
E
K
L
L
K
T
L
G
Y
--
K
D
F
P
V
I
P
T
S
A
W
N
G
DNVVK
K
S
----------
D
----------
K
M
P
W
Y
---
N
G
-
P
T
L
I
E
A
L
D
Q
-
I
P
E
P
E
K
P
-
I
D
K
P
L
R
I
P
I
Q
D
V
-
Y
S
I
K
G
------
V
G
T
--------
V
P
V
G
R
V
E
T
G
K
L
K
V
G
D
V
V
-------------
I
F
E
P
A
S
T
I
F
HKPIQGE
V
K
S
I
E
M
H
H
E
P
L
Q
E
A
L
P
G
D
N
I
G
F
N
V
---
R
G
V
S
K
N
D
I
K
R
G
D
V
---
A
G
H
TDKP
P
T
V
V
R
T
-
K
D
T
F
K
A
Q
I
I
V
L
N
H
--
P
T
A
I
T
VG
Y
S
P
V
L
H
A
H
T
A
Q
I
P
V
R
F
E
Q
I
-------
L
A
K
V
D
PRTGN
I
V
E
E
N
P
Q
F
I
K
T
G
D
S
A
I
V
V
L
R
P
M
K
P
V
V
L
E
P
V
K
EIPQLG
R
F
A
I
R
D
M
----
G
M
T
I
A
A
G
M
V
I
S
I
Q
K
103
Fugue
70.83
31%
-79
- C3 -
1KK1
3
IF2G_PYRAB
A:
[6-410]
-------
S
R
Q
A
E
V
N
I
G
M
V
G
H
V
D
H
G
K
T
T
L
T
K
A
L
T
--------
G
V
W
T
D
--
S
--------
E
-
E
--------
L
R
RGITIK
I
G
F
A
D
A
E
----------
I
R
R
C
P
N
C
G
R
Y
S
T
S
P
V
C
P
Y
C
G
--------------
H
E
T
E
F
V
--------------
R
R
V
S
F
I
D
A
P
G
H
E
A
L
M
T
T
M
L
A
G
A
S
L
M
D
G
A
I
L
V
I
A
A
N
E
P
C
P
R
P
-------
Q
T
R
E
H
L
M
A
L
Q
I
I
G
Q
K
N
I
I
I
A
Q
N
K
I
E
L
V
D
---
K
E
K
A
L
E
N
Y
R
-
Q
I
K
E
F
I
E
G
T
--
V
A
E
N
A
P
I
I
P
I
S
A
L
H
---------------------------------
G
---
A
N
I
D
V
L
V
K
A
I
E
D
F
I
P
T
P
K
R
D
-
P
N
K
P
P
K
M
L
V
L
R
S
-
F
D
V
N
K
------
P
G
K
LV
G
G
----
V
L
D
G
S
I
V
Q
G
K
L
K
V
G
D
E
I
E
I
R
P
G
V
P
Y
E
E
HG
R
I
K
Y
E
P
I
T
T
E
-------
I
V
S
L
Q
A
G
G
Q
F
V
E
E
A
Y
P
G
G
L
V
G
V
G
T
KLD
P
Y
L
T
K
G
D
L
M
A
G
N
V
---
V
G
K
----
P
G
K
L
P
P
V
W
D
S
L
R
L
E
V
H
L
L
E
R
VV
E
Q
E
L
K
--
V
E
P
I
K
R
K
E
V
L
L
L
N
V
G
T
A
R
T
-------
M
G
L
V
------
T
G
L
G
K
D
---------
E
I
E
V
K
L
Q
I
P
V
C
A
E
P
G
D
------
R
V
A
I
S
R
Q
I
GS
R
W
R
L
I
G
Y
G
I
I
K
E
---
68
PsiBlast_CBE
70.44
34%
-70
- C3 -
4CXH
2
EF1A_AERPE
A:
[4-428]
---------
K
P
H
M
N
L
V
V
I
G
H
V
D
H
G
K
S
T
L
V
G
H
L
-----------
L
Y
R
--
L
--------
G
-
Y
IE
E
K
K
L
K
E
L
E
-------
E
Q
A
K
S
R
GKESF
K
F
A
W
I
L
D
K
M
K
E
E
R
E
R
G
I
T
I
D
L
T
F
M
K
--------------
F
E
-
T
K
K
--------------
Y
V
F
T
I
I
D
A
P
G
H
R
D
F
V
K
N
M
I
T
G
A
S
Q
A
D
A
A
I
L
V
V
S
A
R
K
G
-
E
F
E
A
G
M
STEG
Q
T
R
E
H
L
L
L
A
R
T
M
G
I
E
Q
I
I
V
A
V
N
K
M
D
A
P
D
VNY
D
Q
K
R
Y
E
F
V
V
S
V
L
K
K
F
M
K
G
L
G
Y
Q
V
D
K
I
P
F
I
P
V
S
A
W
K
G
DNLIE
R
S
----------
P
----------
N
M
P
W
Y
---
N
G
-
P
T
L
V
E
A
L
D
Q
L
Q
P
-
P
A
K
P
-
V
D
K
P
L
R
I
P
V
Q
N
V
-
Y
S
I
P
G
------
A
G
T
--------
V
P
V
G
R
V
E
T
G
V
L
R
V
G
D
K
V
V
F
M
PP-------
G
V
V
G
E
------------
V
R
S
I
E
M
H
Y
Q
Q
L
Q
Q
A
E
P
G
D
N
I
G
F
A
V
---
R
G
V
S
K
S
D
I
K
R
G
D
V
A
G
H
L
D
K
----
P
P
T
V
A
---
E
E
F
E
A
R
I
F
V
I
W
H
--
P
S
A
I
T
VG
Y
T
P
V
I
H
V
H
T
A
S
V
S
S
R
I
I
E
I
KAKLDPK
T
G
Q
V
-------
V
E
Q
N
P
Q
F
L
K
A
G
D
A
A
I
V
R
F
K
P
V
K
P
L
V
V
E
K
F
S
EIPQLG
R
F
A
M
R
D
M
----
N
R
T
V
G
I
G
I
V
T
D
V
K
-
70
PsiBlast_CBE
70.24
34%
-70
- C3 -
3VMF
3
EF1A_AERPE
A:
[7-430]
---------
K
P
H
M
N
L
V
V
I
G
H
V
D
H
G
K
S
T
L
V
G
H
L
-----------
L
Y
R
--
L
--------
G
-
Y
IE
E
K
K
L
K
E
L
E
-------
E
Q
A
K
S
R
GKESF
K
F
A
W
I
L
D
K
M
K
E
E
R
E
R
G
I
T
I
D
L
T
F
M
K
--------------
F
E
-
T
K
K
--------------
Y
V
F
T
I
I
D
A
P
G
H
R
D
F
V
K
N
M
I
T
G
A
S
Q
A
D
A
A
I
L
V
V
S
A
R
K
G
-
E
F
E
A
G
M
STEG
Q
T
R
E
H
L
L
L
A
R
T
M
G
I
E
Q
I
I
V
A
V
N
K
M
D
A
P
D
VNY
D
Q
K
R
Y
E
F
V
V
S
V
L
K
K
F
M
K
G
L
G
Y
Q
V
D
K
I
P
F
I
P
V
S
A
W
K
G
DNLIE
R
S
----------
P
----------
N
M
P
W
Y
---
N
G
-
P
T
L
V
E
A
L
D
Q
L
Q
P
-
P
A
K
P
-
V
D
K
P
L
R
I
P
V
Q
N
V
-
Y
S
I
P
G
------
A
G
T
--------
V
P
V
G
R
V
E
T
G
V
L
R
V
G
D
K
V
V
F
M
PP-------
G
V
V
G
E
------------
V
R
S
I
E
M
H
Y
Q
Q
L
Q
Q
A
E
P
G
D
N
I
G
F
A
V
---
R
G
V
S
K
S
D
I
K
R
G
D
V
A
G
H
L
D
K
----
P
P
T
V
A
---
E
E
F
E
A
R
I
F
V
I
W
H
--
P
S
A
I
T
VG
Y
T
P
V
I
H
V
H
T
A
S
V
S
S
R
I
I
E
I
KAKLDPK
T
G
Q
V
-------
V
E
Q
N
P
Q
F
L
K
A
G
D
A
A
I
V
R
F
K
P
V
K
P
L
V
V
E
K
F
S
EIPQLG
R
F
A
M
R
D
M
----
N
R
T
V
G
I
G
I
V
T
D
V
--
66
PsiBlast_CBE
68.80
36%
-78
- C3 -
3WY9
1
EF1A_PYRHO
B:
[5-426]
---------
K
P
H
V
N
I
V
F
I
G
H
V
D
H
G
K
S
T
T
I
G
R
L
L
YDTGNIPE
T
I
I
K
K
FE---------
S
-
F
--------
K
F
-------
A
W
V
M
D
R
----------
L
K
---
E
E
R
E
R
G
I
T
I
D
V
A
H
T
K
--------------
F
E
-
T
P
H
--------------
R
Y
I
T
I
I
D
A
P
G
H
R
D
F
V
K
N
M
I
T
G
A
S
Q
A
D
A
A
V
L
V
V
A
A
T
D
G
-
V
M
P
-------
Q
T
K
E
H
A
F
L
A
R
T
L
G
I
K
H
I
I
V
T
I
N
K
M
D
M
V
N
Y--
D
Q
K
V
F
E
K
V
K
A
Q
V
E
K
L
L
K
T
L
G
Y
--
K
D
F
P
V
I
P
T
S
A
W
N
G
DNVVK
K
S
----------
D
----------
K
M
P
W
Y
---
N
G
-
P
T
L
I
E
A
L
D
Q
-
I
P
E
P
E
K
P
-
I
D
K
P
L
R
I
P
I
Q
D
V
-
Y
S
I
K
G
------
V
G
T
--------
V
P
V
G
R
V
E
T
G
K
L
K
V
G
D
V
V
-------------
I
F
E
P
A
S
T
I
F
HKPIQGE
V
K
S
I
E
M
H
H
E
P
L
Q
E
A
L
P
G
D
N
I
G
F
N
V
---
R
G
V
S
K
N
D
I
K
R
G
D
V
---
A
G
H
TDKP
P
T
V
V
R
T
-
K
D
T
F
K
A
Q
I
I
V
L
N
H
--
P
T
A
I
T
VG
Y
S
P
V
L
H
A
H
T
A
Q
I
P
V
R
F
E
Q
I
-------
L
A
K
V
DPRTGN
I
V
E
E
N
P
Q
F
I
K
T
G
D
S
A
I
V
V
L
R
P
M
K
P
V
V
L
E
P
V
K
EIPQLG
R
F
A
I
R
D
M
----
G
M
T
I
A
A
G
M
V
I
S
I
Q
K
45
PsiBlast_CBE
63.46
74%
-121
- C3 -
1ETU
2
EFTU1_ECOLI
A:
[5-200]
-----
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--------
T
V
L
A
K
--
T
--------
Y
-
G
--------------------------------------------
I
T
I
N
T
S
H
V
E
--------------
Y
D
-
T
P
T
--------------
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
-------
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
---
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
-----
L
E
----------
G
----------
D
A
E
W
E
---
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
59.36
32%
-81
- C3 -
4M4S
22
IF2G_SULSO
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSD
D
E
P
K
F
L
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
A
D
V
N
A
P
G
TQFNEL
K
G
G
--------
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
56.91
32%
-85
- C3 -
4RD0
4
IF2G_SULSO
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
A
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
56.40
32%
-83
- C3 -
4RCZ
3
IF2G_SULSO
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
56.13
32%
-85
- C3 -
2PMD
3
IF2G_SULSO
B:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
TNIGVCESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELKGG
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
55.71
32%
-101
- C3 -
2QN6
3
IF2G_SULSO
A:
[2-262]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
---------------------------------------------------------------
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
55.56
32%
-86
- C3 -
4RD6
2
?
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
---------
K
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSD
D
E
P
K
F
L
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
54.62
32%
-82
- C3 -
3V11
4
IF2G_SULSO
A:
[6-260]
---------
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
CESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
54.49
32%
-81
- C3 -
2PMD
4
IF2G_SULSO
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
C
ESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
54.45
32%
-83
- C3 -
2QMU
2
IF2G_SULSO
A:
[2-255]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
C
ESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
53.92
32%
-89
- C3 -
3I1F
1
IF2G_SULSO
B:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
TNIGVCESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELKGG
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
53.31
32%
-88
- C3 -
2AHO
3
IF2G_SULSO
A:
[2-260]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
---------------------------------------------------------
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
C
ESCKKPEA
Y
V
-
T
E
P
SCKSCGSDDEPKFL
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
52.72
34%
-74
- C3 -
3PEN
7
IF2G_SULSO
A:
[2-244]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
--------
K
-
L
--------
G
Y
-------
A
E
T
N
I
G
----------
V
C
E
S
C
K
K
P
E
A
Y
V
T
E
P
S
C
K
S
C
--------------
G
S
-
D
D
E
PKFL----------
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
52.28
34%
-75
- C3 -
4M53
19
IF2G_SULSO
A:
[3-245]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
--------
K
-
L
--------
G
Y
-------
A
E
T
N
I
G
----------
V
C
E
S
C
K
K
P
E
A
Y
V
T
E
P
S
C
K
S
C
--------------
G
S
-
D
D
E
PKFL----------
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
51.30
33%
-80
- C3 -
3SJZ
3
IF2G_SULSO
A:
[2-250]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
HSEETIKL
G
-
Y
--------
A
E
-------
T
N
I
--
G
----------
V
C
E
S
C
K
K
P
E
A
Y
V
T
E
P
S
C
K
S
C
--------------
G
S
-
D
D
E
PKFL----------
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
51.24
33%
-82
- C3 -
4M2L
20
IF2G_SULSO
A:
[3-251]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
------TIKL----
G
-
Y
--------
A
E
-------
T
N
I
--
G
----------
V
C
E
S
C
K
K
P
E
A
Y
V
T
E
P
S
C
K
S
C
--------------
G
S
-
D
D
E
PKFL----------
R
R
I
S
F
I
D
A
P
---
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELK
G
G
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
49.47
32%
-64
- C3 -
3QSY
2
IF2G_SULSO
A:
[3-256]
-----
W
P
K
V
Q
P
E
V
N
I
G
V
V
G
H
V
D
H
G
K
T
T
L
V
Q
A
I
T
--------
G
I
W
T
S
--
K
-----------------------------------------------
H
S
E
E
L
K
R
G
M
T
I
K
L
G
Y
A
E
T
N
I
G
V
C
E
SCKKPEA
Y
V
-
T
E
P
SCKSCGS
D
D
E
P
K
F
L
R
R
I
S
F
I
D
A
P
G
H
E
V
L
M
A
T
M
L
S
G
A
A
L
M
D
G
A
I
L
V
V
A
A
N
E
P
F
P
Q
P
-------
Q
T
R
E
H
F
V
A
L
G
I
I
G
V
K
N
L
I
I
V
Q
N
K
V
D
V
V
S
---
K
E
E
A
L
S
Q
Y
R
-
Q
I
K
Q
-
F
T
K
G
T
W
-
A
E
N
V
P
I
I
P
V
S
A
L
H
K
-----
I
N
-------------------------------
I
D
S
L
I
E
G
I
E
E
Y
I
K
T
P
Y
R
D
L
S
Q
K
P
V
M
L
V
I
R
S
--
F
D
V
N
K
------
P
G
T
QFNELKGG
V
I
G
G
S
I
I
Q
G
L
F
K
V
D
Q
E
I
K
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
Fugue
1.90
54%
150
- C3 -
2P8W
1
S:
[1-35]
------------------------------------------
T
A
A
E
--
N
--------
P
-
N
--------
V
E
-------
V
K
D
Y
G
D
----------
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------