@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2654: (2016-04-06 )
MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRVVFVNKMDKIGADFLYSVGTLHERLAANAHPIQLPIGAEDTFEGIIDLIEMNALYYEDDLGNDPHIKEIPADLKDLADEYRGKLVEAVAELDEELMMKYLEGEEITKEELKAGIRKGTLNVEFYPVVCGTAFKNKGVQPMLDAVLDYLPAPTDVPAINGVLPDGEEAARHADDSEPFSSLAFKVMTDPYVGRLTFFRVYSGTLNSGSYVQNSTKGKRERVGRILQMHANHREEISIVYAGDIAAAVGLKDTTTGDTLCDEKEQIILESMEFPEPVIQVAIEPKSKADQDKMGQALAKLAEEDPTFRAETDQETGQTLISGMGELHLDILVDRMRREFRVEANVGDPQVSYRETFRKSAQVEGKFVRQSGGRGQYGHVWIEFGPNEEGKGFEFENAIVGGVVPREYIPAVQAGLEGALDNGVLAGYPLIDIKAKLYDGSYHDVDSNEMAFKVAASMALRNAAKKCDPVILEPMMAVEVVIPEEYLGDIMGNITSRRGRVDGMEARGNAQVVRAFVPLANMFGYATHLRSGTQGRGVYTMQFDHYEEVPKSIAEEIIKANGGNNKED
Atome Classification :
(24 SA)
--------.........10........20........30........40........50........60........70...-------.....80........90........100.......110.......120.......130.......140--....-...150.......160.....--..170..-------------------.....180......-.190......-------------------.200.......210.......220.......230.......240--........250.......260.......270.......280.......290------..--.--..--...300.......310.......320........330.......340...---------....350.......360.......370.......380........----390.-.--......400........410.......420.......430.......440.......450.......460.....-..470.......480...-.------------------------------------------...490.......500.......510.....---..520.......530.......540.......550.......560.......570.........580.......590.......600.......610.......620.......630....--...640.......650.......660.......670.....------..680.......690...-------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MAREFSLEKTRNI
G
I
M
A
H
IDAGKTTT
T
E
R
I
L
F
YTG
R
I
H
KIGETHEG
A
S
Q
M
D
W
M
E
Q
E
Q
ER
G
I
T
I
T
SAATT
A
Q
WK
G
-------
Y
R
V
N
I
I
DTPG
H
V
D
F
T
V
E
V
E
RS
L
R
V
LD
G
A
V
A
V
L
DAQSGVEP
Q
T
E
T
V
W
R
QATTYGV
P
R
V
V
F
VN
K
M
D
K
I
G
A
--
D
F
L
Y
-
S
V
G
T
L
H
E
R
L
AANAH
P
I
QLPIG--
A
E
D
T
F
E
G
-------------------
I
I
D
L
I
E
MN
A
L
Y
YED-DLGNDP
H
I
K
E
-------------------I
P
A
D
L
K
D
L
A
D
E
Y
R
G
K
L
V
E
A
V
A
E
L
D
E
E
L
M
M
K
Y
LEGEEI
T
K
E
E
L
K
---
A
G
I
RKG
T
L
N
V
E
F
Y
P
V
VCGTAFKNKG
V
Q
P
M
L
D
A
V
L
D
YLPAPTDVPAINGVL-------P
D
--
G
--
E
E
--
A
ARHADDSE
P
F
S
S
L
A
F
K
VMTDPYVG-
R
L
T
F
F
R
V
YSGTLNSGSYVQNSTKG---------
K
R
E
R
V
G
R
I
L
Q
M
HANHR
E
E
I
S
I
V
Y
AGD
I
A
A
AVGLKDT-TTGDTLC
D
----
E
-
K
E
-
Q
--
I
I
L
E
SMEF-PE
P
V
I
Q
V
A
IEPKSKA
D
Q
D
K
M
G
Q
A
L
A
K
L
AEEDPTFRAET
D
Q
E
T
G
Q
T
L
I
S
G
M
G
E
L
H
L
D
I
L
V
D
R
M
R
R
E
F
-
R
V
EANVGDPQ
V
S
Y
R
E
T
F
R
-
K
------------------------------------------
S
AQVE
G
K
F
V
RQSGGRGQY
G
H
V
W
I
E
FGPNEEG---KGFEFENAIVGGVV
P
R
E
Y
I
P
A
V
Q
A
GLEGALDNGVLAGY
P
L
I
D
I
K
A
K
LYDGSYH--DVDSN
E
M
A
F
K
V
A
A
S
M
A
L
R
N
A
A
KKCD
P
V
I
LEP
M
M
A
V
E
V
VI
P
E
E
Y
L
G
D
I
M
G
N
I
T
SRRGRVDGMEARG
N
--
A
Q
V
V
R
A
F
V
P
L
A
N
M
F
G
Y
A
T
HLRSGTQGR
G
V
Y
T
M
QF
D
H
Y
E
E
V
P
------
K
S
I
A
E
E
I
I
KANGGNNKED-------------
21
PsiBlast_CBE
95.13
78%
-88
- C2 -
2XEX
2
EFG_STAAU
B:
[2-692]
---------
A
R
E
F
S
L
E
K
T
R
N
I
G
I
M
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
K
I
G
----
G
A
S
Q
M
D
W
M
E
Q
E
--------
S
A
A
T
T
A
A
W
E
G
-------
H
R
V
N
I
I
D
T
P
G
H
V
D
F
T
V
E
V
E
R
S
L
R
V
L
D
G
A
V
T
V
L
D
A
Q
S
G
V
E
P
Q
T
E
T
V
W
R
Q
A
T
T
Y
G
V
P
R
I
V
F
V
N
K
M
D
K
L
G
A
--
N
F
E
Y
-
S
V
S
T
L
H
D
R
L
Q
A
N
A
A
P
I
Q
L
P
I
G
--
A
E
D
E
F
E
A
-------------------
I
I
D
L
V
E
M
K
C
F
K
Y
T
N
-
D
L
G
T
E
I
E
E
I
E
-------------------
I
P
E
D
H
L
D
R
A
E
E
A
R
A
S
L
I
E
A
V
A
E
T
S
D
E
L
M
E
K
Y
L
G
D
E
E
I
S
V
S
E
L
K
---
E
A
I
R
Q
A
T
T
N
V
E
F
Y
P
V
L
C
G
T
A
F
K
N
K
G
V
Q
L
M
L
D
A
V
I
D
Y
L
P
S
P
L
D
V
K
P
I
I
G
H
R
-------
A
S
--
N
PE
E
E
--
V
I
A
K
A
D
D
S
A
E
F
A
A
L
A
F
K
V
M
T
D
P
Y
V
G
-
K
L
T
F
F
R
V
Y
S
G
T
M
T
S
G
S
Y
V
K
N
S
T
K
G
---------
K
R
E
R
V
G
R
L
L
Q
M
H
A
N
S
R
Q
E
I
D
T
V
Y
S
G
D
I
A
A
A
V
G
L
K
D
T
-
G
T
G
D
T
L
C
G
----
E
-
K
N
-
D
--
I
I
L
E
S
M
E
F
-
P
E
P
V
I
H
L
S
V
E
P
K
S
K
A
D
Q
D
K
M
T
Q
A
L
V
K
L
Q
E
E
D
P
T
F
H
A
H
T
-----
Q
V
I
I
G
G
M
G
E
L
H
L
D
I
L
V
D
R
M
K
K
E
F
-
N
V
E
C
N
V
G
A
P
M
V
S
Y
R
E
T
F
K
-
S
------------------------------------------
S
A
Q
V
Q
G
K
F
S
R
Q
S
G
G
R
G
Q
Y
G
D
V
H
I
E
F
T
P
N
E
T
G
---
A
G
F
E
F
E
N
A
I
V
G
G
V
V
P
R
E
Y
I
P
S
V
E
A
G
L
K
D
A
M
E
N
G
V
L
A
G
Y
P
L
I
D
V
K
A
K
L
Y
D
G
S
Y
H
--
D
V
D
S
S
E
M
A
F
K
I
A
A
S
L
A
L
K
E
A
A
K
K
C
D
P
V
I
L
E
P
M
M
K
V
T
I
E
M
P
E
E
Y
M
G
D
I
M
G
D
V
T
S
R
R
G
R
V
D
G
M
E
P
R
G
N
--
A
Q
V
V
N
A
Y
V
P
L
S
E
M
F
G
Y
A
T
S
L
R
S
N
T
Q
G
R
G
T
Y
T
M
Y
F
D
H
Y
A
E
V
P
------
K
S
I
A
E
D
I
I
K
K
N
K
G
------------------
1
PsiBlast_PDB
92.56
78%
-88
* C2 *
2XEX
2
EFG_STAAU
A:
[2-692]
---------
A
R
E
F
S
L
E
K
T
R
N
I
G
I
M
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
-------------------------
T
S
A
A
T
T
A
A
W
E
G
-------
H
R
V
N
I
I
D
T
P
G
H
V
D
F
T
V
E
V
E
R
S
L
R
V
L
D
G
A
V
T
V
L
D
A
Q
S
G
V
E
P
Q
T
E
T
V
W
R
Q
A
T
T
Y
G
V
P
R
I
V
F
V
N
K
M
D
K
L
G
A
--
N
F
E
Y
-
S
V
S
T
L
H
D
R
L
Q
A
N
A
A
P
I
Q
L
P
I
G
--
A
E
D
E
F
E
A
-------------------
I
I
D
L
V
E
M
K
C
F
K
Y
T
N
-
D
L
G
T
E
I
E
E
I
E
-------------------
I
P
E
D
H
L
D
R
A
E
E
A
R
A
S
L
I
E
A
V
A
E
T
S
D
E
L
M
E
K
Y
L
G
D
E
E
I
S
V
S
E
L
K
---
E
A
I
R
Q
A
T
T
N
V
E
F
Y
P
V
L
C
G
T
A
F
K
N
K
G
V
Q
L
M
L
D
A
V
I
D
Y
L
P
S
P
L
D
V
K
P
I
I
G
H
R
-------
A
S
--
N
PE
E
E
--
V
I
A
K
A
D
D
S
A
E
F
A
A
L
A
F
K
V
M
T
D
P
Y
V
G
-
K
L
T
F
F
R
V
Y
S
G
T
M
T
S
G
S
Y
V
K
N
S
T
K
G
---------
K
R
E
R
V
G
R
L
L
Q
M
H
A
N
S
R
Q
E
I
D
T
V
Y
S
G
D
I
A
A
A
V
G
L
K
D
T
-
G
T
G
D
T
L
C
G
----
E
-
K
N
-
D
--
I
I
L
E
S
M
E
F
-
P
E
P
V
I
H
L
S
V
E
P
K
S
K
A
D
Q
D
K
M
T
Q
A
L
V
K
L
Q
E
E
D
P
T
F
H
A
H
T
---
T
G
Q
V
I
I
G
G
M
G
E
L
H
L
D
I
L
V
D
R
M
K
K
E
F
-
N
V
E
C
N
V
G
A
P
M
V
S
Y
R
E
T
F
K
-
S
------------------------------------------
S
A
Q
V
Q
G
K
F
S
R
Q
S
G
G
R
G
Q
Y
G
D
V
H
I
E
F
T
P
N
E
T
G
---
A
G
F
E
F
E
N
A
I
V
G
G
V
V
P
R
E
Y
I
P
S
V
E
A
G
L
K
D
A
M
E
N
G
V
L
A
G
Y
P
L
I
D
V
K
A
K
L
Y
D
G
S
Y
H
--
D
V
D
S
S
E
M
A
F
K
I
A
A
S
L
A
L
K
E
A
A
K
K
C
D
P
V
I
L
E
P
M
M
K
V
T
I
E
M
P
E
E
Y
M
G
D
I
M
G
D
V
T
S
R
R
G
R
V
D
G
M
E
P
R
G
N
--
A
Q
V
V
N
A
Y
V
P
L
S
E
M
F
G
Y
A
T
S
L
R
S
N
T
Q
G
R
G
T
Y
T
M
Y
F
D
H
Y
A
E
V
P
------
K
S
I
A
E
D
I
I
K
K
N
K
G
------------------
105
HHSearch
87.97
78%
-40
- C- -
2XEX
2
EFG_STAAU
A:
[2-693]
---------
A
R
E
F
S
L
E
K
T
R
N
I
G
I
M
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
-------------------------
T
S
A
A
T
T
A
A
W
E
G
-------
H
R
V
N
I
I
D
T
P
G
H
V
D
F
T
V
E
V
E
R
S
L
R
V
L
D
G
A
V
T
V
L
D
A
Q
S
G
V
E
P
Q
T
E
T
V
W
R
Q
A
T
T
Y
G
V
P
R
I
V
F
V
N
K
M
D
K
L
G
A
--
N
F
E
Y
-
S
V
S
T
L
H
D
R
L
Q
A
N
A
A
P
I
Q
L
P
I
G
--
A
E
D
E
F
E
A
-------------------
I
I
D
L
V
E
M
K
C
F
K
Y
T
N
-
D
L
G
T
E
I
E
E
I
E
-------------------
I
P
E
D
H
L
D
R
A
E
E
A
R
A
S
L
I
E
A
V
A
E
T
S
D
E
L
M
E
K
Y
L
G
D
E
E
I
S
V
S
E
L
K
---
E
A
I
R
Q
A
T
T
N
V
E
F
Y
P
V
L
C
G
T
A
F
K
N
K
G
V
Q
L
M
L
D
A
V
I
D
Y
L
P
S
P
L
D
V
K
P
I
I
G
H
R
-------
A
S
NP
E
--
E
E
--
V
I
A
K
A
D
D
S
A
E
F
A
A
L
A
F
K
V
M
T
D
P
Y
V
G
-
K
L
T
F
F
R
V
Y
S
G
T
M
T
S
G
S
Y
V
K
N
S
T
K
G
---------
K
R
E
R
V
G
R
L
L
Q
M
H
A
N
S
R
Q
E
I
D
T
V
Y
S
G
D
I
A
A
A
V
G
L
K
D
T
-
G
T
G
D
T
L
C
G
----
E
-
K
N
-
D
--
I
I
L
E
S
M
E
F
-
P
E
P
V
I
H
L
S
V
E
P
K
S
K
A
D
Q
D
K
M
T
Q
A
L
V
K
L
Q
E
E
D
P
T
F
H
A
H
T
---
T
G
Q
V
I
I
G
G
M
G
E
L
H
L
D
I
L
V
D
R
M
K
K
E
F
-
N
V
E
C
N
V
G
A
P
M
V
S
Y
R
E
T
F
K
-
S
------------------------------------------
S
A
Q
V
Q
G
K
F
S
R
Q
S
G
G
R
G
Q
Y
G
D
V
H
I
E
F
T
P
N
E
T
G
---
A
G
F
E
F
E
N
A
I
V
G
G
V
V
P
R
E
Y
I
P
S
V
E
A
G
L
K
D
A
M
E
N
G
V
L
A
G
Y
P
L
I
D
V
K
A
K
L
Y
D
G
S
Y
H
--
D
V
D
S
S
E
M
A
F
K
I
A
A
S
L
A
L
K
E
A
A
K
K
C
D
P
V
I
L
E
P
M
M
K
V
T
I
E
M
P
E
E
Y
M
G
D
I
M
G
D
V
T
S
R
R
G
R
V
D
G
M
E
P
R
G
N
--
A
Q
V
V
N
A
Y
V
P
L
S
E
M
F
G
Y
A
T
S
L
R
S
N
T
Q
G
R
G
T
Y
T
M
Y
F
D
H
Y
A
E
V
P
------
K
S
I
A
E
D
I
I
K
K
N
K
G
E
-----------------
12
PsiBlast_PDB
87.43
65%
-84
- C2 -
2BM0
2
?
A:
[6-689]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
K
I
A
--------------------
T
I
T
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
A
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
K
----------------------
133
Fugue
87.26
64%
-87
- C2 -
4M1K
2
?
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
---------------------------
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
-
D
A
P
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
L
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
7
PsiBlast_PDB
86.94
65%
-87
- C2 -
4M1K
2
?
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
---------------------------
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
L
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
10
PsiBlast_PDB
86.17
65%
-82
- C2 -
1FNM
2
EFG_THETH
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
----------------------------
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
A
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
9
PsiBlast_PDB
86.16
65%
-83
- C2 -
4MYU
2
EFG_THETH
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
----------------------------
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
K
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
6
PsiBlast_PDB
85.90
65%
-80
- C2 -
2J7K
2
EFG_THETH
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
------------------------
I
T
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
A
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
2
PsiBlast_PDB
85.23
65%
-81
- C2 -
2OM7
-
?
L:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
----------------------------
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
8
PsiBlast_PDB
84.66
65%
-82
- C2 -
2BM1
2
EFG_THETH
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
V
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
-------------------------
I
T
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
5
PsiBlast_PDB
84.34
65%
-75
- C2 -
4MYT
2
EFG_THETH
A:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
---------------------------
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
A
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
13
PsiBlast_PDB
83.64
65%
-69
- C2 -
3IZP
-
?
E:
[6-688]
-----------
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
H
K
I
G
E
V
H
E
G
A
A
T
M
D
F
M
E
Q
E
R
E
R
G
I
T
I
T
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
I
E
V
-
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
E
T
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
-
K
V
D
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
A
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
-----------------------
135
Fugue
79.97
64%
-81
- C2 -
1ELO
-
?
?:
[5-689]
----------
V
E
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
----------------------------
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
-
D
A
-
P
--
R
V
I
L
---------
I
D
V
A
I
E
P
K
S
Q
A
--------
L
A
R
L
A
E
E
D
P
T
F
R
V
S
T
H
P
Q
T
---
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
------
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
K
----------------------
3
PsiBlast_PDB
79.86
65%
-79
- C2 -
2EFG
1
EFG_THET8
A:
[7-689]
------------
Y
D
L
K
R
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
---------------------------
A
A
V
T
T
C
F
W
K
D
-------
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
--
D
L
W
L
-
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
M
Q
L
P
I
G
--
R
E
D
T
F
S
G
-------------------
I
I
D
V
L
R
M
K
A
Y
T
Y
G
N
-
D
L
G
T
D
I
R
E
I
P
-------------------
I
P
E
E
Y
L
D
N
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
---
A
A
I
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
V
V
D
Y
L
P
S
P
L
D
I
P
P
I
K
G
T
T
-------
P
E
--
G
--
E
V
--
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
-
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
---------
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
D
L
G
A
V
V
G
L
K
E
T
-
I
T
G
D
T
L
V
G
----
E
D
A
P
-
R
--
V
I
L
E
S
----------------------------------------------------------------------------
V
G
K
P
Q
V
A
Y
R
E
T
I
T
-
K
------------------------------------------
P
V
D
V
E
G
K
F
I
R
Q
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
---
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
G
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
--
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
--
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
------
K
Q
V
Q
E
K
L
I
K
----------------------
14
PsiBlast_PDB
79.60
62%
-65
- C2 -
3J0E
2
EFG_ECOLI
H:
[1-702]
---------
A
R
T
T
P
I
A
R
Y
R
N
I
G
I
S
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
F
Y
T
G
V
N
H
K
I
G
E
V
H
D
G
A
A
T
M
D
W
M
E
Q
E
Q
E
R
G
I
T
I
T
S
A
A
T
T
A
F
W
S
G
MAKQYEP
H
R
I
N
I
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
V
M
V
Y
C
A
V
G
G
V
Q
P
Q
S
E
T
V
W
R
Q
A
N
K
Y
K
V
P
R
I
A
F
V
N
K
M
D
R
M
G
A
--
N
F
L
K
-
V
V
N
Q
I
K
T
R
L
G
A
N
P
V
P
L
Q
L
A
I
G
--
A
E
E
H
F
T
G
-------------------
V
V
D
L
V
K
M
K
A
I
N
W
N
D
A
D
Q
G
V
T
F
E
Y
E
D
-------------------
I
P
A
D
M
V
E
L
A
N
E
W
H
Q
N
L
I
E
S
A
A
E
A
S
E
E
L
M
E
K
Y
L
G
G
E
E
L
T
E
A
E
I
K
---
G
A
L
R
Q
R
V
L
N
N
E
I
I
L
V
T
C
G
S
A
F
K
N
K
G
V
Q
A
M
L
D
A
V
I
D
Y
L
P
S
P
V
D
V
P
A
I
N
G
I
L
-------
D
D
--
G
--
K
D
TP
A
E
R
H
A
S
D
D
E
P
F
S
A
L
A
F
K
I
A
T
D
P
F
V
G
-
N
L
T
F
F
R
V
Y
S
G
V
V
N
S
G
D
T
V
L
N
S
V
K
A
---------
A
R
E
R
F
G
R
I
V
Q
M
H
A
N
K
R
E
E
I
K
E
V
R
A
G
D
I
A
A
A
I
G
L
K
D
V
-
T
T
G
D
T
L
C
D
----
P
-
D
A
-
P
--
I
I
L
E
R
M
E
F
-
P
E
P
V
I
S
I
A
V
E
P
K
T
K
A
D
Q
E
K
M
G
L
A
L
G
R
L
A
K
E
D
P
S
F
R
V
W
T
D
E
E
S
N
Q
T
I
I
A
G
M
G
E
L
H
L
D
I
I
V
D
R
M
K
R
E
F
-
N
V
E
A
N
V
G
K
P
Q
V
A
Y
R
E
T
I
R
Q
K
------------------------------------------
V
T
D
V
E
G
K
H
A
K
Q
S
G
G
R
G
Q
Y
G
H
V
V
I
D
M
Y
P
L
E
P
G
SNP
K
G
Y
E
F
I
N
D
I
K
G
G
V
I
P
G
E
Y
I
P
A
V
D
K
G
I
Q
E
Q
L
K
A
G
P
L
A
G
Y
P
V
V
D
M
G
I
R
L
H
F
G
S
Y
H
--
D
V
D
S
S
E
L
A
F
K
L
A
A
S
I
A
F
K
E
G
F
K
K
A
K
P
V
L
L
E
P
I
M
K
V
E
V
E
T
P
E
E
N
T
G
D
V
I
G
D
L
S
R
R
R
G
M
L
K
G
Q
E
S
E
V
T
--
G
V
K
I
H
A
E
V
P
L
S
E
M
F
G
Y
A
T
Q
L
R
S
L
T
K
G
R
A
S
Y
T
M
E
F
L
K
Y
D
E
A
P
------
S
N
V
A
Q
A
V
I
E
A
R
G
-------------------
107
HHSearch
71.94
35%
-69
- C2 -
2DY1
2
?
A:
[6-664]
--------------
G
A
M
I
R
T
V
A
L
V
G
H
A
G
S
G
K
T
T
L
T
E
A
L
L
Y
K
T
G
A
K
E
R
R
G
R
V
E
E
G
T
T
T
T
D
Y
T
P
E
A
K
L
H
R
T
T
V
R
T
G
V
A
P
L
L
F
R
G
-------
H
R
V
F
L
L
D
A
P
G
Y
G
D
F
V
G
E
I
R
G
A
L
E
A
A
D
A
A
L
V
A
V
S
A
E
A
G
V
Q
V
G
T
E
R
A
W
T
V
A
E
R
L
G
L
P
R
M
V
V
V
T
K
L
D
K
G
G
---
D
Y
Y
A
-
L
L
E
D
L
R
S
T
L
G
P
-
I
L
P
I
D
L
P
L
Y
--
E
G
G
K
W
V
G
-------------------
L
I
D
V
F
H
G
K
A
Y
R
Y
E
N
-
G
E
E
R
E
---
A
E
-------------------
V
P
P
E
E
R
E
R
V
Q
R
F
R
Q
E
V
L
E
A
I
V
E
T
D
E
G
L
L
E
K
Y
L
E
G
E
E
V
T
G
E
A
L
E
---
K
A
F
H
E
A
V
R
R
G
L
L
Y
P
V
A
L
A
S
G
E
R
E
I
G
V
L
P
L
L
E
L
I
L
E
A
L
P
S
P
T
E
R
F
------------------------------
G
D
G
P
P
L
A
K
V
F
K
V
Q
V
D
P
F
M
G
-
Q
V
A
Y
L
R
L
Y
R
G
R
L
K
P
G
D
S
L
Q
S
E
A
G
-----------
Q
V
R
L
P
H
L
Y
V
P
M
G
K
D
L
L
E
V
E
E
A
E
A
G
F
V
L
G
V
P
K
A
E
G
L
-
H
R
G
M
V
L
W
Q
----
G
-
E
K
-
P
ES
E
E
V
P
F
A
R
L
-
P
D
P
N
V
P
V
A
L
H
P
K
G
R
T
D
E
A
R
L
G
E
A
L
R
K
L
L
E
E
D
P
S
L
K
L
E
R
Q
E
E
T
G
E
L
L
L
W
G
H
G
E
L
H
L
A
T
A
K
E
R
L
Q
-
D
Y
-
G
V
E
V
E
F
S
V
P
K
V
P
Y
R
E
T
I
K
-
K
------------------------------------------
V
A
E
G
Q
G
K
Y
K
K
Q
T
G
G
H
G
Q
Y
G
D
V
W
L
R
L
E
P
A
S
------
E
Y
G
F
E
W
R
I
T
G
G
V
I
P
S
K
Y
Q
E
A
I
E
E
G
I
K
E
A
A
K
K
G
V
L
A
G
F
P
V
M
G
F
K
A
I
V
Y
N
G
S
Y
H
--
E
V
D
S
S
D
L
A
F
Q
I
A
A
S
L
A
F
K
K
V
M
A
E
A
H
P
V
L
L
E
P
I
Y
R
L
K
V
L
A
P
Q
E
R
V
G
D
V
L
S
D
L
Q
A
R
R
G
R
I
L
G
M
E
Q
E
G
A
--
L
S
V
V
H
A
E
V
P
L
A
E
V
L
E
Y
Y
K
A
L
P
G
L
T
G
G
A
G
A
Y
T
L
E
F
S
H
Y
A
E
V
P
------
P
H
L
A
Q
R
I
V
Q
E
R
A
Q
E
-----------------
17
PsiBlast_PDB
71.76
34%
-73
- C2 -
2DY1
2
?
A:
[10-659]
------------------
R
T
V
A
L
V
G
H
A
G
S
G
K
T
T
L
T
E
A
L
L
Y
K
T
G
A
K
E
R
R
G
R
V
E
E
G
T
T
T
T
D
Y
T
P
E
A
K
L
H
R
T
T
V
R
T
G
V
A
P
L
L
F
R
G
-------
H
R
V
F
L
L
D
A
P
G
Y
G
D
F
V
G
E
I
R
G
A
L
E
A
A
D
A
A
L
V
A
V
S
A
E
A
G
V
Q
V
G
T
E
R
A
W
T
V
A
E
R
L
G
L
P
R
M
V
V
V
T
K
L
D
K
-
G
G
--
D
Y
Y
A
-
L
L
E
D
L
R
S
T
L
G
P
I
L
-
P
I
D
L
P
L
Y
--
E
G
G
K
W
V
G
-------------------
L
I
D
V
F
H
G
K
A
Y
R
Y
E
N
----
G
E
E
R
E
A
E
-------------------
V
P
P
E
E
R
E
R
V
Q
R
F
R
Q
E
V
L
E
A
I
V
E
T
D
E
G
L
L
E
K
Y
L
E
G
E
E
V
T
G
E
A
L
E
---
K
A
F
H
E
A
V
R
R
G
L
L
Y
P
V
A
L
A
S
G
E
R
E
I
G
V
L
P
L
L
E
L
I
L
E
A
L
P
S
P
T
E
-----------------------------
R
F
G
D
G
P
P
L
A
K
V
-
F
K
V
Q
V
D
P
F
M
G
-
Q
V
A
Y
L
R
L
Y
R
G
R
L
K
P
G
D
S
L
Q
--
S
E
A
---------
G
Q
V
R
L
P
H
L
Y
V
P
M
G
K
D
L
L
E
V
E
E
A
E
A
G
F
V
L
G
V
P
K
A
E
G
L
-
H
R
G
M
V
L
W
Q
G
EKP
E
-
S
E
-
E
--
V
P
F
A
R
L
---
P
D
P
N
V
P
V
A
L
H
P
K
G
R
T
D
E
A
R
L
G
E
A
L
R
K
L
L
E
E
D
P
S
L
K
L
E
R
Q
E
E
T
G
E
L
L
L
W
G
H
G
E
L
H
L
A
T
A
K
E
R
L
Q
-
D
Y
-
G
V
E
V
E
F
S
V
P
K
V
P
Y
R
E
T
I
K
-
K
------------------------------------------
V
A
E
G
Q
G
K
Y
K
K
Q
T
G
G
H
G
Q
Y
G
D
V
W
L
R
L
E
P
A
S
E
------
Y
G
F
E
W
R
I
T
G
G
V
I
P
S
K
Y
Q
E
A
I
E
E
G
I
K
E
A
A
K
K
G
V
L
A
G
F
P
V
M
G
F
K
A
I
V
Y
N
G
S
Y
H
--
E
V
D
S
S
D
L
A
F
Q
I
A
A
S
L
A
F
K
K
V
M
A
E
A
H
P
V
L
L
E
P
I
Y
R
L
K
V
L
A
P
Q
E
R
V
G
D
V
L
S
D
L
Q
A
R
R
G
R
I
L
G
M
E
Q
E
G
A
--
L
S
V
V
H
A
E
V
P
L
A
E
V
L
E
Y
Y
K
A
L
P
G
L
T
G
G
A
G
A
Y
T
L
E
F
S
H
Y
A
E
V
P
------
P
H
L
A
Q
R
I
V
Q
----------------------
16
PsiBlast_PDB
71.49
34%
-71
- C2 -
1WDT
2
?
A:
[10-659]
------------------
R
T
V
A
L
V
G
H
A
G
S
G
K
T
T
L
T
E
A
L
L
Y
K
T
G
A
K
E
R
R
G
R
V
E
E
G
T
T
T
T
D
Y
T
P
E
A
K
L
H
R
T
T
V
R
T
G
V
A
P
L
L
F
R
G
-------
H
R
V
F
L
L
D
A
P
G
Y
G
D
F
V
G
E
I
R
G
A
L
E
A
A
D
A
A
L
V
A
V
S
A
E
A
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V
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A
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L
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L
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V
V
V
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L
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-
G
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--
D
Y
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L
L
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-
P
I
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L
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Y
--
E
G
G
K
W
V
G
-------------------
L
I
D
V
F
H
G
K
A
Y
R
Y
E
N
----
G
E
E
R
E
A
E
-------------------
V
P
P
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R
E
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L
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V
T
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A
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---
K
A
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P
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T
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-----------------------------
R
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-
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-
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-
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--
V
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---
P
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-
K
------------------------------------------
V
A
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A
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------
Y
G
F
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H
Y
A
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------
P
H
L
A
Q
R
I
V
Q
----------------------
137
Fugue
58.24
24%
-50
- C1 -
1N0V
-
EF2_YEAST
C:
[2-842]
VAFTVDQM
R
S
L
M
D
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V
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N
V
R
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--
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S
-------
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VQVYPARGTVAFGSGLHGW
A
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----
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A
--
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M
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-
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ESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDD
F
K
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I
M
A
D
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T
D
A
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F
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---
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T
S
K
A
G
E
I
V
L
A
A
R
K
R
H
G
M
K
EEVPGWQEYYDKL
22
PsiBlast_CBE
28.68
40%
-35
- C2 -
4ZCM
3
?
B:
[35-224]
-------------
M
I
E
K
L
R
N
I
A
I
I
A
H
V
D
H
G
K
T
T
L
V
D
K
L
L
Q
Q
S
G
--------------------------
T
I
L
A
K
N
T
A
I
K
W
N
D
-------
Y
R
I
N
I
V
D
T
P
G
H
A
D
F
G
G
E
V
E
R
V
M
S
M
V
D
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L
L
V
V
D
A
F
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P
M
P
Q
T
R
F
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T
K
K
A
F
A
Y
G
L
K
P
I
V
V
I
N
K
V
D
R
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A
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D
W
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V
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F
D
L
F
V
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L
D
A
T
D
E
Q
L
D
F
P
I
V
--
Y
A
S
A
L
N
G
-------------------
I
A
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
28.04
40%
-40
- C2 -
4ZCL
2
?
B:
[35-224]
-------------
M
I
E
K
L
R
N
I
A
I
I
A
H
V
D
H
G
K
T
T
L
V
D
K
L
L
Q
Q
S
G
--------------------------
T
I
L
A
K
N
T
A
I
K
W
N
D
-------
Y
R
I
N
I
V
D
T
P
G
H
A
D
F
G
G
E
V
E
R
V
M
S
M
V
D
S
V
L
L
V
V
D
A
F
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P
M
P
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T
R
F
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T
K
K
A
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A
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I
N
K
V
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R
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A
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D
W
V
V
D
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F
D
L
F
V
N
L
D
A
T
D
E
Q
L
D
F
P
I
V
--
Y
A
S
A
L
N
G
-------------------
I
A
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
26.81
40%
-33
- C2 -
4ZCM
3
?
A:
[35-224]
-------------
M
I
E
K
L
R
N
I
A
I
I
A
H
V
D
H
G
K
T
T
L
V
D
K
L
L
Q
Q
S
G
--------------------------
T
I
L
A
K
N
T
A
I
K
W
N
D
-------
Y
R
I
N
I
V
D
T
P
G
H
A
D
F
G
G
E
V
E
R
V
M
S
M
V
D
S
V
L
L
V
V
D
A
F
D
G
P
M
P
Q
T
R
F
V
T
K
K
A
F
A
Y
G
L
K
P
I
V
V
I
N
K
V
D
R
P
G
A
R
P
D
W
V
V
D
Q
V
F
D
L
F
V
N
L
D
A
T
D
E
Q
L
D
F
P
I
V
--
Y
A
S
A
L
N
G
-------------------
I
A
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
25.27
40%
-31
- C2 -
4ZCL
2
?
A:
[35-224]
-------------
M
I
E
K
L
R
N
I
A
I
I
A
H
V
D
H
G
K
T
T
L
V
D
K
L
L
Q
Q
S
G
--------------------------
T
I
L
A
K
N
T
A
I
K
W
N
D
-------
Y
R
I
N
I
V
D
T
P
G
H
A
D
F
G
G
E
V
E
R
V
M
S
M
V
D
S
V
L
L
V
V
D
A
F
D
G
P
M
P
Q
T
R
F
V
T
K
K
A
F
A
Y
G
L
K
P
I
V
V
I
N
K
V
D
R
P
G
A
R
P
D
W
V
V
D
Q
V
F
D
L
F
V
N
L
D
A
T
D
E
Q
L
D
F
P
I
V
--
Y
A
S
A
L
N
G
-------------------
I
A
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------