@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2695: (2016-04-06 )
MKKILNGTDQVVEQMVEGLVKSHADVVHRVEGTRVIARNDKRPGKVGLVSGGGSGHEPAHAGYVGRGMLSAAVCGDVFTSPTPDQIYEGIKAADQGAGVLLIVKNYTGDVMNFEMAADLADADDIKVEQIVVDDDIAVEDSTFTTGRRGVAGTVLVHKIIGAAAEAGASLDELKALGEKVIASVKTLGVALSPCTVPEVGHPGFELGDDEIELGIGIHGEPGFTREKIMPSASLAKQLYERISNESKLLAGDKVVVLVNGMGATPLMEQYVFANDVHELLKNAGVQVEKTLVGDYMTSLEMAGLSLTILKLEDEKWVDMLKLPVDTIAW
Atome Classification :
(27 SA)
.........10.......-.20........30---........40.-.......50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190......------.200.......210.......220......---------.230.......240---------------..------------------------.------------------------....--250.......260.......270.......280.......290.--......300.......310.......320.......----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
K
IL
N
G
T
D
Q
V
V
E
Q
M
V
E
G
-
L
V
K
S
H
A
D
V
V
H
RVE---G
T
R
V
I
ARNDKR-PG
K
V
G
L
VSGGGSGHEPAHAG
Y
V
G
R
G
M
L
S
A
A
V
CGDVFTSP
T
P
D
Q
I
Y
E
G
I
K
A
ADQG
A
G
V
L
L
I
V
KNYTGDVM
N
F
E
M
AADLADADD
I
K
V
E
Q
I
V
VDDDIAVEDSTFTTGRRG
V
A
G
T
V
L
V
H
K
I
I
G
A
A
A
EAGA
S
L
D
E
L
K
A
L
G
E
K
V
I
A
S
V
K
T
L
G
V
ALSPCTVPE------VGHPGFELGDD
E
I
E
L
G
I
G
IHGEPGF
T
R
EKI---------M
P
S
A
S
L
A
K
Q
L
Y
E
R
I---------------SN------------------------E------------------------SKLL--AG
D
K
V
V
V
L
VNGMGA
T
P
L
M
E
Q
Y
V
F
A
N
D
V
H
E
L
L
K
NAG
V
Q
V
E
K
T
L
V
G
--
D
Y
M
T
S
L
EMAG
L
S
L
T
I
L
KLED
E
K
W
V
D
M
L
KLPVDTIAW----
37
HHSearch
99.61
61%
-103
- C6 -
3CT4
1
DHAK_LACLA
A:
[4-331]
-
E
K
I
I
N
Q
P
Q
D
V
V
S
E
M
L
D
G
-
L
T
Y
A
Y
G
D
L
I
E
K
V
P
---
D
F
E
I
I
Q
R
K
S
P
K
-
S
G
K
V
A
L
V
S
G
G
G
S
G
H
E
P
A
H
A
G
F
V
G
E
G
M
L
S
A
A
V
C
G
A
I
F
T
S
P
T
P
D
Q
I
Y
E
A
I
K
S
A
D
E
G
A
G
V
L
L
I
I
K
N
Y
L
G
D
V
M
N
F
E
M
A
R
E
M
A
E
M
E
E
I
K
V
E
Q
I
I
V
D
D
D
I
A
V
E
N
S
L
Y
T
Q
G
R
R
G
V
A
G
T
V
L
V
H
K
I
L
G
A
A
A
H
Q
E
A
S
L
D
E
I
K
D
L
A
D
K
V
V
K
N
I
K
T
I
G
L
A
L
S
A
A
T
V
P
----------------
D
N
E
I
E
Y
G
V
G
I
H
S
E
P
G
Y
R
R
E
K
M
---------
K
T
S
Y
E
L
A
T
E
L
V
G
K
L
---------------
K
E
------------------------
E
------------------------
F
K
F
E
--
A
G
Q
K
Y
G
I
L
V
N
G
M
G
A
T
P
L
M
E
Q
F
I
F
M
N
D
V
A
K
L
L
T
E
E
N
I
E
I
L
F
K
K
V
G
--
N
Y
M
T
S
I
D
M
A
G
L
S
L
T
M
I
K
L
E
D
D
Q
W
L
K
N
L
N
E
D
V
K
T
I
S
W
----
1
PsiBlast_PDB
99.28
60%
-103
- C6 -
3CT4
1
DHAK_LACLA
A:
[4-331]
-
E
K
I
I
N
Q
P
Q
D
V
V
S
E
M
L
D
G
-
L
T
Y
A
Y
G
D
L
I
E
K
V
P
---
D
F
E
I
I
Q
R
K
S
P
K
-
S
G
K
V
A
L
V
S
G
G
G
S
G
H
E
P
A
H
A
G
F
V
G
E
G
M
L
S
A
A
V
C
G
A
I
F
T
S
P
T
P
D
Q
I
Y
E
A
I
K
S
A
D
E
G
A
G
V
L
L
I
I
K
N
Y
L
G
D
V
M
N
F
E
M
A
R
E
M
A
E
M
E
E
I
K
V
E
Q
I
I
V
D
D
D
I
A
V
E
N
S
L
Y
T
Q
G
R
R
G
V
A
G
T
V
L
V
H
K
I
L
G
A
A
A
H
Q
E
A
S
L
D
E
I
K
D
L
A
D
K
V
V
K
N
I
K
T
I
G
L
A
L
S
A
A
T
V
P
----------------
D
N
E
I
E
Y
G
V
G
I
H
S
E
P
G
Y
R
R
E
K
M
---------
K
T
S
Y
E
L
A
T
E
L
V
G
K
L
---------------
K
E
------------------------
E
------------------------
F
K
F
E
--
A
G
Q
K
Y
G
I
L
V
N
G
M
G
A
T
P
L
M
E
Q
F
I
F
M
N
D
V
A
K
L
L
T
E
E
N
I
E
I
L
F
K
K
V
G
--
N
Y
M
T
S
I
D
M
A
G
L
S
L
T
M
I
K
L
E
D
D
Q
W
L
K
N
L
N
E
D
V
K
T
I
S
W
----
21
PsiBlast_CBE
99.01
60%
-101
- C6 -
3CT4
1
DHAK_LACLA
C:
[4-331]
-
E
K
I
I
N
Q
P
Q
D
V
V
S
E
M
L
D
G
-
L
T
Y
A
Y
G
D
L
I
E
K
V
P
---
D
F
E
I
I
Q
R
K
S
P
K
-
S
G
K
V
A
L
V
S
G
G
G
S
G
H
E
P
A
H
A
G
F
V
G
E
G
M
L
S
A
A
V
C
G
A
I
F
T
S
P
T
P
D
Q
I
Y
E
A
I
K
S
A
D
E
G
A
G
V
L
L
I
I
K
N
Y
L
G
D
V
M
N
F
E
M
A
R
E
M
A
E
M
E
E
I
K
V
E
Q
I
I
V
D
D
D
I
A
V
E
N
S
L
Y
T
Q
G
R
R
G
V
A
G
T
V
L
V
H
K
I
L
G
A
A
A
H
Q
E
A
S
L
D
E
I
K
D
L
A
D
K
V
V
K
N
I
K
T
I
G
L
A
L
S
A
A
T
V
P
----------------
D
N
E
I
E
Y
G
V
G
I
H
S
E
P
G
Y
R
R
E
K
M
---------
K
T
S
Y
E
L
A
T
E
L
V
G
K
L
---------------
K
E
------------------------
E
------------------------
F
K
F
E
--
A
G
Q
K
Y
G
I
L
V
N
G
M
G
A
T
P
L
M
E
Q
F
I
F
M
N
D
V
A
K
L
L
T
E
E
N
I
E
I
L
F
K
K
V
G
--
N
Y
M
T
S
I
D
M
A
G
L
S
L
T
M
I
K
L
E
D
D
Q
W
L
K
N
L
N
E
D
V
K
T
I
S
W
----
22
PsiBlast_CBE
99.00
60%
-102
- C6 -
3CT4
1
DHAK_LACLA
B:
[4-331]
-
E
K
I
I
N
Q
P
Q
D
V
V
S
E
M
L
D
G
-
L
T
Y
A
Y
G
D
L
I
E
K
V
P
---
D
F
E
I
I
Q
R
K
S
P
K
-
S
G
K
V
A
L
V
S
G
G
G
S
G
H
E
P
A
H
A
G
F
V
G
E
G
M
L
S
A
A
V
C
G
A
I
F
T
S
P
T
P
D
Q
I
Y
E
A
I
K
S
A
D
E
G
A
G
V
L
L
I
I
K
N
Y
L
G
D
V
M
N
F
E
M
A
R
E
M
A
E
M
E
E
I
K
V
E
Q
I
I
V
D
D
D
I
A
V
E
N
S
L
Y
T
Q
G
R
R
G
V
A
G
T
V
L
V
H
K
I
L
G
A
A
A
H
Q
E
A
S
L
D
E
I
K
D
L
A
D
K
V
V
K
N
I
K
T
I
G
L
A
L
S
A
A
T
V
P
----------------
D
N
E
I
E
Y
G
V
G
I
H
S
E
P
G
Y
R
R
E
K
M
---------
K
T
S
Y
E
L
A
T
E
L
V
G
K
L
---------------
K
E
------------------------
E
------------------------
F
K
F
E
--
A
G
Q
K
Y
G
I
L
V
N
G
M
G
A
T
P
L
M
E
Q
F
I
F
M
N
D
V
A
K
L
L
T
E
E
N
I
E
I
L
F
K
K
V
G
--
N
Y
M
T
S
I
D
M
A
G
L
S
L
T
M
I
K
L
E
D
D
Q
W
L
K
N
L
N
E
D
V
K
T
I
S
W
----
54
Fugue
92.41
45%
-98
* C6 *
1OI2
2
DHAK_ECOLI
A:
[20-366]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
---------
S
S
L
D
Q
T
V
D
E
M
F
D
T
L
---------------
L
V
------------------------
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
K
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
-
D
D
E
T
L
A
L
W
D
A
P
V
H
T
P
A
L
N
W
G
K
39
HHSearch
92.32
46%
-98
- C6 -
1OI2
2
DHAK_ECOLI
A:
[20-362]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
-
L
T
L
H
Q
---
D
P
V
Y
V
T
R
A
D
A
P
V
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
---------
S
S
L
D
Q
T
V
D
E
M
F
D
T
L
---------------
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
-
E
T
L
A
L
W
D
A
P
V
H
T
P
A
L
----
23
PsiBlast_CBE
90.28
44%
-84
- C6 -
1UOE
2
DHAK_ECOLI
B:
[20-361]
---------
Q
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDNTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
25
PsiBlast_CBE
90.24
44%
-87
- C6 -
1OI3
1
DHAK_ECOLI
B:
[20-361]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
13
PsiBlast_PDB
90.07
41%
-98
- C6 -
2IU6
1
DHAQ_LACLA
A:
[2-328]
--
E
F
Y
N
S
T
N
E
I
P
E
E
M
L
K
G
-
I
D
L
T
Y
P
Q
L
T
Y
L
P
E
----
T
G
I
L
Y
D
N
T
Y
N
-
E
K
T
V
P
I
I
S
G
G
G
S
G
H
E
P
A
H
V
G
Y
V
G
S
G
M
L
A
A
A
V
T
G
P
L
F
I
P
P
K
S
K
N
I
L
K
A
I
R
Q
V
N
S
G
K
G
V
F
V
I
I
K
N
F
E
A
D
L
K
E
F
N
E
A
I
K
E
A
R
T
E
G
I
D
V
R
Y
I
V
S
H
D
D
I
S
V
N
A
Y
N
F
H
K
R
H
R
G
V
A
G
T
I
L
L
H
K
I
L
G
A
F
A
K
E
G
G
S
I
D
E
I
E
Q
L
A
L
S
L
S
P
E
I
Y
T
L
G
V
A
L
------------------------
E
V
S
F
G
I
G
I
H
G
E
P
G
Y
R
V
E
K
F
---------
E
G
S
E
R
I
A
I
E
L
V
N
K
L
---------------
K
A
------------------------
E
------------------------
I
N
W
Q
KK
A
N
K
N
Y
I
L
L
V
N
G
L
G
S
T
T
L
M
E
L
Y
S
F
Q
Y
D
V
M
R
L
L
E
L
E
G
L
S
V
K
F
C
K
V
G
--
N
L
M
T
S
C
D
M
S
G
I
S
L
T
L
C
S
V
K
D
P
K
W
L
D
Y
L
N
V
P
T
G
A
F
A
W
----
2
PsiBlast_PDB
90.05
44%
-85
- C6 -
1UOE
2
DHAK_ECOLI
A:
[20-361]
---------
Q
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
N
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
31
PsiBlast_CBE
89.90
41%
-95
- C6 -
2IU6
1
DHAQ_LACLA
B:
[2-328]
--
E
F
Y
N
S
T
N
E
I
P
E
E
M
L
K
G
-
I
D
L
T
Y
P
Q
L
T
Y
L
P
E
----
T
G
I
L
Y
D
N
T
Y
N
-
E
K
T
V
P
I
I
S
G
G
G
S
G
H
E
P
A
H
V
G
Y
V
G
S
G
M
L
A
A
A
V
T
G
P
L
F
I
P
P
K
S
K
N
I
L
K
A
I
R
Q
V
N
S
G
K
G
V
F
V
I
I
K
N
F
E
A
D
L
K
E
F
N
E
A
I
K
E
A
R
T
E
G
I
D
V
R
Y
I
V
S
H
D
D
I
S
V
N
A
Y
N
F
H
K
R
H
R
G
V
A
G
T
I
L
L
H
K
I
L
G
A
F
A
K
E
G
G
S
I
D
E
I
E
Q
L
A
L
S
L
S
P
E
I
Y
T
L
G
V
A
L
A
P
V
--------------------
D
E
V
S
F
G
I
G
I
H
G
E
P
G
Y
R
V
E
K
F
---------
E
G
S
E
R
I
A
I
E
L
V
N
K
L
---------------
K
A
------------------------
E
------------------------
I
N
W
Q
KK
A
N
K
N
Y
I
L
L
V
N
G
L
G
S
T
T
L
M
E
L
Y
S
F
Q
Y
D
V
M
R
L
L
E
L
E
G
L
S
V
K
F
C
K
V
G
--
N
L
M
T
S
C
D
M
S
G
I
S
L
T
L
C
S
V
K
D
P
K
W
L
D
Y
L
N
V
P
T
G
A
F
A
W
----
3
PsiBlast_PDB
89.88
44%
-84
- C6 -
1OI2
2
DHAK_ECOLI
A:
[20-361]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
24
PsiBlast_CBE
89.87
44%
-85
- C6 -
1UOD
2
DHAK_ECOLI
B:
[20-361]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
12
PsiBlast_PDB
89.72
43%
-88
- C6 -
3PNM
-
DHAK_ECOLI
A:
[10-351]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
A
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
-------------
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
26
PsiBlast_CBE
89.69
44%
-85
- C6 -
1OI2
2
DHAK_ECOLI
B:
[20-361]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
5
PsiBlast_PDB
89.58
44%
-83
- C6 -
1UOD
2
DHAK_ECOLI
A:
[20-361]
---------
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
-----------------
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
9
PsiBlast_PDB
89.48
44%
-84
- C6 -
4LRY
1
DHAK_ECOLI
A:
[1-351]
M
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
L
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
6
PsiBlast_PDB
89.48
44%
-84
- C6 -
4LRX
1
DHAK_ECOLI
A:
[1-351]
M
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SS
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
28
PsiBlast_CBE
89.43
44%
-84
- C6 -
3PNK
1
DHAK_ECOLI
B:
[3-352]
-
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
8
PsiBlast_PDB
89.41
44%
-82
- C6 -
3PNL
3
DHAK_ECOLI
A:
[3-352]
-
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
S
S
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
7
PsiBlast_PDB
89.36
44%
-84
- C6 -
3PNK
1
DHAK_ECOLI
A:
[3-352]
-
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
S
S
L
D
Q
T
V
D
E
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
L
R
F
W
DYQQG
S
W
Q
E
E
Q
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
29
PsiBlast_CBE
89.22
44%
-84
- C6 -
4LRY
1
DHAK_ECOLI
B:
[1-351]
M
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
L
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
27
PsiBlast_CBE
89.11
44%
-83
- C6 -
4LRX
1
DHAK_ECOLI
B:
[1-351]
M
K
K
L
I
N
D
V
Q
D
V
L
D
E
Q
L
A
G
-
L
A
K
A
H
P
S
L
T
L
H
Q
D
---
P
V
Y
V
T
R
A
D
A
P
V
-
A
G
K
V
A
L
L
S
G
G
G
S
G
H
E
P
M
H
C
G
Y
I
G
Q
G
M
L
S
G
A
C
P
G
E
I
F
T
S
P
T
P
D
K
I
F
E
C
A
M
Q
V
D
G
G
E
G
V
L
L
I
I
K
N
Y
T
G
D
I
L
N
F
E
T
A
T
E
L
L
H
D
S
G
V
K
V
T
T
V
V
I
D
D
D
V
A
V
K
D
S
L
Y
T
A
G
R
R
G
V
A
N
T
V
L
I
E
K
L
V
G
A
A
A
E
R
G
D
S
L
D
A
C
A
E
L
G
R
K
L
N
N
Q
G
H
S
I
G
I
A
L
G
A
C
T
V
P
A
------
A
G
K
P
S
F
T
L
A
D
N
E
M
E
F
G
V
G
I
H
G
E
P
G
I
D
R
R
P
F
SSLDQTVDE
M
F
D
T
L
L
V
N
G
S
Y
H
R
T
LRFWDYQQGSWQEEQ
Q
T
------------------------
K
------------------------
Q
P
L
Q
--
S
G
D
R
V
I
A
L
V
N
N
L
G
A
T
P
L
S
E
L
Y
G
V
Y
N
R
L
T
T
R
C
Q
Q
A
G
L
T
I
E
R
N
L
I
G
--
A
Y
C
T
S
L
D
M
T
G
F
S
I
T
L
L
K
V
D
D
E
T
-
L
A
L
W
D
A
P
V
H
T
P
A
-----
34
PsiBlast_CBE
82.98
36%
-86
- C6 -
1UN9
1
DHAK_CITFR
B:
[5-340]
---
F
F
N
Q
R
T
H
L
V
S
D
V
I
D
G
A
I
I
A
S
P
W
N
N
L
A
R
L
E
SDP
A
I
R
I
V
V
R
R
D
L
N
-
K
N
N
V
A
V
I
S
G
G
G
S
G
H
E
P
A
H
V
G
F
I
G
K
G
M
L
T
A
A
V
C
G
D
V
F
A
S
P
S
V
D
A
V
L
T
A
I
Q
A
V
T
G
E
A
G
C
L
L
I
V
K
N
Y
T
G
D
R
L
N
F
G
L
A
A
E
K
A
R
R
L
G
Y
N
V
E
M
L
I
V
G
D
D
I
S
L
P
D
N
K
H
P
---
R
G
I
A
G
T
I
L
V
H
K
I
A
G
Y
F
A
E
R
G
Y
N
L
A
T
V
L
R
E
A
Q
Y
A
A
S
N
T
F
S
L
G
V
A
L
S
S
C
H
L
P
Q
ETDAAP
R
H
H
P
G
------
H
A
E
L
G
M
G
I
H
G
E
P
G
A
S
V
I
D
T
---------
Q
N
S
A
Q
V
V
N
L
M
V
D
K
L
-----------------------------------------
L
------------------------
A
A
L
P
--
E
T
G
R
L
A
V
M
I
N
N
L
G
G
V
S
V
A
E
M
A
I
I
---
T
R
E
L
A
S
S
P
L
H
S
R
I
D
W
L
I
G
PA
S
L
V
T
A
L
D
M
K
G
F
S
L
T
A
I
V
L
E
-
E
S
I
E
K
A
L
L
T
E
V
E
T
S
N
W
----
16
PsiBlast_PDB
82.96
36%
-87
- C6 -
1UN9
1
DHAK_CITFR
A:
[5-340]
---
F
F
N
Q
R
T
H
L
V
S
D
V
I
D
G
A
I
I
A
S
P
W
N
N
L
A
R
L
E
SDP
A
I
R
I
V
V
R
R
D
L
N
-
K
N
N
V
A
V
I
S
G
G
G
S
G
H
E
P
A
H
V
G
F
I
G
K
G
M
L
T
A
A
V
C
G
D
V
F
A
S
P
S
V
D
A
V
L
T
A
I
Q
A
V
T
G
E
A
G
C
L
L
I
V
K
N
Y
T
G
D
R
L
N
F
G
L
A
A
E
K
A
R
R
L
G
Y
N
V
E
M
L
I
V
G
D
D
I
S
L
P
D
N
K
H
P
---
R
G
I
A
G
T
I
L
V
H
K
I
A
G
Y
F
A
E
R
G
Y
N
L
A
T
V
L
R
E
A
Q
Y
A
A
S
N
T
F
S
L
G
V
A
L
S
S
C
H
L
P
Q
ETDAA
P
R
H
H
P
G
------
H
A
E
L
G
M
G
I
H
G
E
P
G
A
S
V
I
D
T
---------
Q
N
S
A
Q
V
V
N
L
M
V
D
K
L
-----------------------------------------
L
------------------------
A
A
L
P
--
E
T
G
R
L
A
V
M
I
N
N
L
G
G
V
S
V
A
E
M
A
I
I
---
T
R
E
L
A
S
S
P
L
H
S
R
I
D
W
L
I
G
PA
S
L
V
T
A
L
D
M
K
G
F
S
L
T
A
I
V
L
E
-
E
S
I
E
K
A
L
L
T
E
V
E
T
S
N
W
----
38
HHSearch
69.52
41%
-83
- C6 -
2IU4
4
DHAQ_LACLA
A:
[8-214]
--------
N
E
I
P
E
E
M
L
K
G
-
I
D
L
T
Y
P
Q
-
L
T
Y
L
P
---
E
T
G
I
L
Y
D
N
T
Y
N
-
E
K
T
V
P
I
I
S
G
G
G
S
G
H
E
P
A
H
V
G
Y
V
G
S
G
M
L
A
A
A
V
T
G
P
L
F
I
P
P
K
S
K
N
I
L
K
A
I
R
Q
V
N
S
G
K
G
V
F
V
I
I
K
N
F
E
A
D
L
K
E
F
N
E
A
I
K
E
A
R
T
E
G
I
D
V
R
Y
I
V
S
H
D
D
I
S
V
N
A
Y
N
F
H
K
R
H
R
G
V
A
G
T
I
L
L
H
K
I
L
G
A
F
A
K
E
G
G
S
I
D
E
I
E
Q
L
A
L
S
L
S
P
E
I
Y
T
L
G
V
A
L
A
P
V
H
F
P
H
------
Q
-
K
T
S
F
V
L
A
E
D
E
V
S
F
G
I
G
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
69.42
40%
-86
- C6 -
2IU4
4
DHAQ_LACLA
A:
[8-214]
--------
N
E
I
P
E
E
M
L
K
G
-
I
D
L
T
Y
P
Q
L
T
Y
L
P
E
----
T
G
I
L
Y
D
N
T
Y
N
-
E
K
T
V
P
I
I
S
G
G
G
S
G
H
E
P
A
H
V
G
Y
V
G
S
G
M
L
A
A
A
V
T
G
P
L
F
I
P
P
K
S
K
N
I
L
K
A
I
R
Q
V
N
S
G
K
G
V
F
V
I
I
K
N
F
E
A
D
L
K
E
F
N
E
A
I
K
E
A
R
T
E
G
I
D
V
R
Y
I
V
S
H
D
D
I
S
V
N
A
Y
N
F
H
K
R
H
R
G
V
A
G
T
I
L
L
H
K
I
L
G
A
F
A
K
E
G
G
S
I
D
E
I
E
Q
L
A
L
S
L
S
P
E
I
Y
T
L
G
V
A
L
A
P
V
H
F
P
H
-------
Q
K
T
S
F
V
L
A
E
D
E
V
S
F
G
I
G
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------