@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2700: (2016-04-06 )
MTLSFSDTYRLNNGIEMPRHGFGVYKLTDEARMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFFDTWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNHLLHRYLEELHIVHQAWSPLGRGGVLQEQILIDLAEKHGKSPAQIVLRWHLQNNISIIPKSETPSRIRENAAIYDFELSEADMRQVERLNTGERVSHAPDVMYVRSEI
Atome Classification :
(92 SA)
.........10.-.......20........30........40........50........60----.----..------...-----.----.70.........80........90--........100.......110.--.----------------------.--------------------.--.--------------------.--.120--------------.........130.......140.......150-....--...--.160.......170.......180.......190--.-------..----------.----------.---.----------.200.......210.......220..----.....230.......240.......250---.......--260...---....270.......280
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTLSFSD
T
Y
RLN-NGIEMPRHGF
G
V
Y
K
L
T
D
E
A
R
M
R
T
A
L
E
T
A
V
D
V
G
Y
R
LFD
T
A
S
F
YH
N
E
K
E
L
G
----
D
----
F
F
------
A
SS-----G----LK-RD
E
F
F
V
T
T
KMWNTEQ
G
Y
D
E
T
L
--
R
A
F
E
K
S
Q
K
KLQLDQ
I
D
L
Y
L
V
HW--P----------------------K--------------------Q--D--------------------
T
--
F
F
----------------
D
T
W
R
A
V
E
K
L
Y
D
E
G
L
V
R
A
IGVSNF
E
A
H
H
L
D
R
L
--RTSA--NVL--
P
V
V
D
Q
LETHPHF
P
N
H
L
L
H
R
Y
L
E
E
L
H
I
V
H
Q
A
WSPL--G-------RG----------G----------
V
---
L
----------
Q
E
Q
I
L
I
D
L
A
E
K
HGK
S
P
A
Q
I
V
L
R
W
HLQ----NN
I
S
I
I
PKSE
T
P
S
R
I
REN
A
A
I
Y
D
F
ELS
E
---
A
D
M
R
Q
V
E
--RLNTGE---RVSHAP
D
V
M
Y
VRSEI
24
PsiBlast_CBE
95.25
49%
-79
- C9 -
3D3F
1
GR_BACSU
B:
[3-271]
---
S
L
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
----
G
I
------
K
E
S
-----
G
----
V
A
-
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
--
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
Y
K
----------------
D
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
--
L
K
D
A
--
E
I
K
--
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
----
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
---
E
D
M
D
K
I
D
--
A
L
N
K
D
E
---
R
V
G
P
N
P
D
--------
104
HHSearch
95.17
49%
-77
- C9 -
3F7J
7
GR_BACSU
A:
[1-272]
M
P
T
S
L
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
----
G
I
------
K
E
S
-----
G
----
V
A
-
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
--
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
Y
K
----------------
D
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
--
L
K
D
A
--
E
I
K
--
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
----
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
---
E
D
M
D
K
I
D
--
A
L
N
K
D
E
---
R
V
G
P
N
P
D
--------
23
PsiBlast_CBE
94.79
48%
-79
- C9 -
3F7J
7
GR_BACSU
B:
[1-272]
M
P
T
S
L
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
----
G
I
------
K
E
S
-----
G
----
V
A
-
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
--
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
Y
K
----------------
D
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
--
L
K
D
A
--
E
I
K
--
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
----
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
---
E
D
M
D
K
I
D
--
A
L
N
K
D
E
---
R
V
G
P
N
P
D
--------
4
PsiBlast_PDB
94.61
48%
-77
- C9 -
3F7J
7
GR_BACSU
A:
[1-272]
M
P
T
S
L
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
----
G
I
------
K
E
S
-----
G
----
V
A
-
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
--
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
Y
K
----------------
D
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
--
L
K
D
A
--
E
I
K
--
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
----
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
---
E
D
M
D
K
I
D
--
A
L
N
K
D
E
---
R
V
G
P
N
P
D
--------
5
PsiBlast_PDB
94.56
49%
-75
- C9 -
3D3F
1
GR_BACSU
A:
[3-271]
---
S
L
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
----
G
I
------
K
E
S
-----
G
----
V
A
-
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
--
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
Y
K
----------------
D
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
--
L
K
D
A
--
E
I
K
--
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
----
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
---
E
D
M
D
K
I
D
--
A
L
N
K
D
E
---
R
V
G
P
N
P
D
--------
22
PsiBlast_CBE
93.86
46%
-73
- C9 -
1VBJ
2
PGFS_TRYBB
B:
[6-276]
--
M
A
L
T
Q
S
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
----
A
I
------
A
S
C
-----
G
----
V
P
-
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
F
I
----------------
D
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
--
L
K
H
C
--
K
V
A
--
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
--
G
-------
Q
G
----------
H
----------
L
---
V
----------
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
----
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
---
E
D
I
Q
V
I
D
--
G
M
N
A
G
H
---
R
Y
G
P
D
P
E
V
-------
2
PsiBlast_PDB
93.15
46%
-79
- C9 -
4GIE
2
PGFS_TRYCC
A:
[14-289]
------
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
----
G
I
------
R
E
S
-----
G
----
V
P
-
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
--
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
K
--------------------
K
--
F
V
----------------
D
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
--
F
K
S
C
--
K
I
R
--
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
--
G
-------
S
G
EEA-------
G
----------
I
---
L
----------
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
----
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
---
E
E
M
R
Q
I
D
--
E
L
N
E
D
K
---
R
I
G
A
D
P
D
N
F
F
P
G
G
E
-
3
PsiBlast_PDB
92.89
46%
-79
- C9 -
1VBJ
2
PGFS_TRYBB
A:
[6-276]
--
M
A
L
T
Q
S
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
----
A
I
------
A
S
C
-----
G
----
V
P
-
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
F
I
----------------
D
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
--
L
K
H
C
--
K
V
A
--
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
--
G
-------
Q
G
----------
H
----------
L
---
V
----------
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
----
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
---
E
D
I
Q
V
I
D
--
G
M
N
A
G
H
---
R
Y
G
P
D
P
E
V
-------
102
HHSearch
92.74
46%
-79
- C9 -
1VBJ
2
PGFS_TRYBB
A:
[8-275]
----
L
T
Q
S
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
----
A
I
------
A
S
C
-----
G
----
V
P
-
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
D
--------------------
K
--
F
I
----------------
D
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
--
L
K
H
C
--
K
V
A
--
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
--
G
-------
Q
G
----------
H
----------
L
---
V
----------
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
----
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
---
E
D
I
Q
V
I
D
--
G
M
N
A
G
H
---
R
Y
G
P
D
P
E
--------
1
PsiBlast_PDB
92.05
46%
-77
- C9 -
4FZI
1
PGFS_TRYCC
A:
[14-289]
------
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
----
G
I
------
R
E
S
-----
G
----
V
P
-
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
--
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
K
--------------------
K
--
F
V
----------------
D
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
--
F
K
S
C
--
K
I
R
--
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
--
G
-------
S
G
EEA-------
G
----------
I
---
L
----------
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
----
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
---
E
E
M
R
Q
I
D
--
E
L
N
E
D
K
---
R
I
G
A
D
P
D
N
F
F
P
G
G
E
-
25
PsiBlast_CBE
91.76
44%
-78
- C9 -
4G5D
1
PGFS_LEIMA
B:
[15-284]
----------
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
----
G
L
------
R
A
S
-----
G
----
V
P
-
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
--
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
R
--------------------
G
--
K
D
I
L
S
K
EGK------------
K
--
Y
L
----------------
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
--
L
A
M
C
--
T
V
T
--
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
--
G
-------
Q
G
----------
K
----------
L
---
L
----------
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
----
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
---
E
D
V
M
S
I
D
--
A
L
N
T
N
S
---
R
Y
G
P
D
P
D
--------
21
PsiBlast_CBE
91.14
46%
-80
- C9 -
4FZI
2
PGFS_TRYCC
B:
[14-288]
------
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
----
G
I
------
R
E
S
-----
G
----
V
P
-
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
--
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
G
--------------------
K
--
K
--------------------
K
--
F
V
----------------
D
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
--
F
K
S
C
--
K
I
R
--
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
--
G
-------
S
----------------------
I
---
L
----------
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
----
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
---
E
E
M
R
Q
I
D
--
E
L
N
E
D
K
---
R
I
G
A
D
P
D
N
F
F
P
G
G
--
7
PsiBlast_PDB
90.94
44%
-80
- C9 -
4G5D
1
PGFS_LEIMA
A:
[15-284]
----------
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
----
G
L
------
R
A
S
-----
G
----
V
P
-
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
--
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
R
--------------------
G
--
K
D
I
L
S
K
EGK------------
K
--
Y
L
----------------
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
--
L
A
M
C
--
T
V
T
--
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
--
G
-------
Q
G
----------
K
----------
L
---
L
----------
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
----
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
---
E
D
V
M
S
I
D
--
A
L
N
T
N
S
---
R
Y
G
P
D
P
D
--------
9
PsiBlast_PDB
90.91
44%
-77
- C9 -
3B3D
1
YTBE_BACSU
A:
[35-310]
M
T
T
H
L
Q
A
K
A
T
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G
S
E
L
V
N
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
----
G
I
R
E
G
I
--
E
E
A
-----
G
----
I
S
-
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
--
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
V
--------------------
E
--
G
--------------------
K
--
Y
K
----------------
E
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
Q
I
H
H
L
E
D
L
--
M
T
A
A
--
E
I
K
--
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
Q
G
I
Q
M
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
----
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
---
D
D
M
N
R
I
D
--
A
L
N
E
N
L
---
R
V
G
P
D
P
D
--------
30
PsiBlast_CBE
90.72
44%
-76
- C9 -
3B3D
1
YTBE_BACSU
C:
[35-310]
M
T
T
H
L
Q
A
K
A
T
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G
S
E
L
V
N
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
----
G
I
REGI--
E
E
A
-----
G
----
I
S
-
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
--
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
V
--------------------
E
--
G
--------------------
K
--
Y
K
----------------
E
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
Q
I
H
H
L
E
D
L
--
M
T
A
A
--
E
I
K
--
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
Q
G
I
Q
M
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
----
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
---
D
D
M
N
R
I
D
--
A
L
N
E
N
L
---
R
V
G
P
D
P
D
--------
31
PsiBlast_CBE
90.57
44%
-80
- C9 -
3B3D
1
YTBE_BACSU
B:
[38-310]
---
H
L
Q
A
K
A
T
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G
S
E
L
V
N
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
----
G
I
R
E
G
I
--
E
E
A
-----
G
----
I
S
-
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
--
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
V
--------------------
E
--
G
--------------------
K
--
Y
K
----------------
E
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
Q
I
H
H
L
E
D
L
--
M
T
A
A
--
E
I
K
--
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
Q
G
I
Q
M
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
----
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
---
D
D
M
N
R
I
D
--
A
L
N
E
N
L
---
R
V
G
P
D
P
D
--------
26
PsiBlast_CBE
90.37
44%
-79
- C9 -
4F40
10
PGFS_LEIMA
B:
[15-284]
----------
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
----
G
L
------
R
A
S
-----
G
----
V
P
-
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
--
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
R
--------------------
G
--
K
DILSKEGK------------
K
--
Y
L
----------------
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
--
L
A
M
C
--
T
V
T
--
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
--
G
-------------------
K
----------
L
---
L
----------
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
----
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
---
E
D
V
M
S
I
D
--
A
L
N
T
N
S
---
R
Y
G
P
D
P
D
--------
106
HHSearch
89.49
45%
-71
- C9 -
3B3D
1
YTBE_BACSU
A:
[37-310]
---
T
H
L
Q
A
K
A
T
L
H
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G
S
E
L
V
N
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
----
G
I
------
R
E
G
I
E
E
A
-
G
----
I
S
-
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
--
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
W
--
P
----------------------
V
--------------------
E
--
G
--------------------
K
--
Y
K
----------------
E
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
Q
I
H
H
L
E
D
L
--
M
T
A
A
--
E
I
K
--
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
Q
G
I
Q
M
E
A
W
S
P
L
--
M
-------
Q
G
----------
Q
----------
L
---
L
----------
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
----
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
---
D
D
M
N
R
I
D
--
A
L
N
E
N
L
---
R
V
G
P
D
P
D
--------
6
PsiBlast_PDB
89.34
44%
-78
- C9 -
4F40
11
PGFS_LEIMA
A:
[15-284]
----------
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
----
G
L
------
R
A
S
-----
G
----
V
P
-
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
--
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
W
--
P
----------------------
R
--------------------
G
--
K
D
I
L
S
K
EGK------------
K
--
Y
L
----------------
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
--
L
A
M
C
--
T
V
T
--
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
--
G
-------------------
K
----------
L
---
L
----------
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
----
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
---
E
D
V
M
S
I
D
--
A
L
N
T
N
S
---
R
Y
G
P
D
P
D
--------
35
PsiBlast_CBE
89.26
44%
-81
- C9 -
4Q3M
1
?
C:
[5-265]
---------
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
-
S
K
K
N
D
A
Y
N
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
----
A
I
------
K
D
S
-----
N
----
I
P
-
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
--
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
W
--
F
----------------------
K
G
-------------------
Y
--
D
--------------------
N
--
A
L
----------------
S
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
N
V
H
H
L
M
Y
L
--
M
E
N
A
--
K
I
P
--
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
N
N
I
Q
L
E
A
Y
A
P
L
--
M
-------
S
H
----------
Q
----------
I
K
D
L
L
----------
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
----
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
---
E
D
M
K
S
I
R
--
S
V
N
T
G
K
---
K
I
-------------
11
PsiBlast_PDB
88.45
41%
-79
- C9 -
1MZR
4
DKGA_ECOLI
A:
[23-292]
---
A
N
P
T
V
I
K
L
Q
-
D
G
N
V
M
P
Q
L
G
L
G
V
W
Q
A
S
N
E
-
E
V
I
T
A
I
Q
K
A
L
E
V
G
Y
R
S
I
D
T
A
A
A
Y
K
N
E
E
G
V
G
----
K
----
A
L
------
K
N
A
-----
S
----
V
N
-
R
E
E
L
F
I
T
T
K
L
W
N
D
D
--
H
K
R
P
R
--
E
A
L
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
W
--
P
----------------------
V
--------------------
P
AI
D
--------------------
H
--
Y
V
----------------
E
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
Q
I
H
H
L
Q
R
L
--
I
D
E
T
--
G
V
T
--
P
V
I
N
Q
I
E
L
H
P
L
M
Q
Q
R
Q
L
H
A
W
N
A
T
H
K
I
Q
T
E
S
W
S
P
L
--
A
-------
Q
G
----------
G
KG--------
V
---
F
----------
D
Q
K
V
I
R
D
L
A
D
K
Y
G
K
T
P
A
Q
I
V
I
R
W
H
L
D
----
S
G
L
V
V
I
P
K
S
V
T
P
S
R
I
A
E
N
F
D
V
W
D
F
R
L
D
K
---
D
E
L
G
E
I
A
--
K
L
D
Q
G
K
---
R
L
G
P
D
P
D
--------
52
PsiBlast_CBE
87.65
39%
-79
- C9 -
1M9H
2
DKGA_CORSC
A:
[8-275]
----------
L
N
-
D
G
N
S
I
P
Q
L
G
Y
G
V
Y
K
V
P
-
P
A
D
T
Q
R
A
V
E
E
A
L
E
V
G
Y
R
H
I
D
T
A
A
I
Y
G
N
E
E
G
V
G
----
A
----
A
I
------
A
A
S
-----
G
----
I
A
-
R
D
D
L
F
I
T
T
K
L
W
N
D
R
H
D
G
D
E
P
A
--
A
A
I
A
E
S
L
A
K
L
A
L
D
Q
V
D
L
Y
L
V
H
W
PT
P
----------------------
A
--------------------
A
--
D
--------------------
N
--
Y
V
----------------
H
A
W
E
K
M
I
E
L
R
A
A
G
L
T
R
S
I
G
V
S
N
H
L
V
P
H
L
E
R
I
--
V
A
A
T
--
G
V
V
--
P
A
V
N
Q
I
E
L
H
P
A
Y
Q
Q
R
E
I
T
D
W
A
A
A
H
D
V
K
I
E
S
W
G
P
L
--
G
-------
Q
G
KY--------
D
----------
L
---
F
----------
G
A
E
P
V
T
A
A
A
A
A
H
G
K
T
P
A
Q
A
V
L
R
W
H
L
Q
----
K
G
F
V
V
F
P
G
S
V
R
R
E
H
L
E
E
N
L
D
V
F
D
F
D
L
T
D
---
T
E
I
A
A
I
D
--
A
M
D
P
G
D
GSG
R
V
S
G
H
P
D
--------
103
HHSearch
87.57
44%
-82
- C9 -
3O0K
4
?
A:
[21-283]
S
M
I
M
T
V
P
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
-
D
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
----
A
I
------
N
G
S
-----
G
----
I
A
-
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
W
--
P
----------------------
M
--------------------
P
--
S
K
D
------------------
L
--
F
M
----------------
E
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
--
I
K
E
S
--
G
V
T
--
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
--
G
-------
Q
G
---------------------
L
---
L
----------
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
----
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
---
T
D
H
D
A
I
T
--
K
L
D
---------------------
118
HHSearch
87.43
37%
-74
- C9 -
3H7U
2
AKRC9_ARATH
A:
[24-308]
----
A
I
T
F
F
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
P
-
G
L
V
G
D
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
----
A
----
V
L
------
K
K
L
F
E
D
R-
V
----
V
K
-
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
--
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
W
--
P
----------------------
A
--------------------
R
--
I
K
K
GSVGIKPENLLPV-----
D
--
I
P
----------------
S
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
T
K
K
L
A
D
L
--
L
E
L
A
--
R
V
P
--
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
K
G
V
H
L
S
A
Y
S
P
L
--
G
-------
S
P
----------
G
----------
T
---
T
WLKSDVL---
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
----
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
---
Y
M
F
A
K
F
A
--
E
I
E
Q
A
-------------------
28
PsiBlast_CBE
87.29
45%
-84
- C9 -
3O0K
3
?
C:
[28-283]
-------
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
E
A
V
-
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
----
A
I
------
N
G
S
-----
G
----
I
A
-
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
W
--
P
MP--------------------
S
--------------------
K
--
D
--------------------
L
--
F
M
----------------
E
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
--
I
K
E
S
--
G
V
T
--
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
--
G
------------------------------
L
---
L
----------
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
----
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
---
T
D
H
D
A
I
T
--
K
L
D
---------------------
50
PsiBlast_CBE
87.26
36%
-82
- C9 -
4GAC
2
AK1A1_MOUSE
B:
[7-303]
----------
L
H
-
T
G
Q
K
M
P
L
I
G
L
G
T
W
K
-
S
E
P
G
Q
V
K
A
A
I
K
H
A
L
S
A
G
Y
R
H
I
D
C
A
S
V
Y
G
N
E
T
E
I
G
----
E
----
A
L
------
K
E
S
VGSGK
A
----
V
P
-
R
E
E
L
F
V
T
S
K
L
W
N
T
K
H
H
P
E
D
V
E
--
P
A
L
R
K
T
L
A
D
L
Q
L
E
Y
L
D
L
Y
L
M
H
W
--
P
Y
A
F
E
------------------
R
--------------------
G
--
D
--------------------
N
--
P
F
PKGTVRYDSTH
Y
K
---
E
T
W
K
A
L
E
V
L
V
A
K
G
L
V
K
A
L
G
L
S
N
F
N
S
R
Q
I
D
D
V
--
L
S
V
A
--
S
V
R
--
P
A
V
L
Q
V
E
C
H
P
Y
L
A
Q
N
E
L
I
A
H
C
H
A
R
G
L
E
V
T
A
Y
S
P
L
--
G
--------------------PDEPV-----
L
---
L
----------
E
E
P
V
V
L
A
L
A
E
K
H
G
R
S
P
A
Q
I
L
L
R
W
Q
V
Q
----
R
K
V
I
C
I
P
K
S
I
N
P
S
R
I
L
Q
N
I
Q
V
F
D
F
T
F
S
P
---
E
E
M
K
Q
L
D
--
A
L
N
K
N
W
---
R
--------------
47
PsiBlast_CBE
87.20
36%
-82
- C9 -
3H4G
3
AK1A1_PIG
A:
[8-301]
----------
L
H
-
T
G
Q
K
M
P
L
I
G
L
G
T
W
K
-
S
E
P
G
Q
V
K
A
A
I
K
Y
A
L
T
V
G
Y
R
H
I
D
C
A
A
I
Y
G
N
E
L
E
I
G
----
E
----
A
L
Q
E
T
VG-
P
G
K
-----
A
----
V
P
-
R
E
E
L
F
V
T
S
K
L
W
N
T
K
H
H
P
E
D
V
E
--
P
A
L
R
K
T
L
A
D
L
Q
L
E
Y
L
D
L
Y
L
M
H
W
--
P
Y
A
F
E
------------------
R
--------------------
G
--
D
--------------------
N
--
P
F
P
K
N
ADGTIRYDATH
Y
K
D
T
W
K
A
L
E
A
L
V
A
K
G
L
V
R
A
L
G
L
S
N
F
S
S
R
Q
I
D
D
V
--
L
S
V
A
--
S
V
R
--
P
A
V
L
Q
V
E
C
H
P
Y
L
A
Q
N
E
L
I
A
H
C
Q
A
R
G
L
E
V
T
A
Y
S
P
L
--
G
-------
S
S
----------
D
RAWRDPNEPV
L
---
L
----------
E
E
P
V
V
Q
A
L
A
E
K
Y
N
R
S
P
A
Q
I
L
L
R
W
Q
V
Q
----
R
K
V
I
C
I
P
K
S
V
T
P
S
R
I
L
Q
N
I
Q
V
F
D
F
T
F
S
P
---
E
E
M
K
Q
L
D
--
A
L
N
K
N
L
---
R
--------------
27
PsiBlast_CBE
87.14
45%
-80
- C9 -
3O0K
3
?
D:
[28-283]
-------
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
E
A
V
-
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
----
A
I
------
N
G
S
-----
G
----
I
A
-
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
W
--
P
MP--------------------
S
--------------------
K
--
D
--------------------
L
--
F
M
----------------
E
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
--
I
K
E
S
--
G
V
T
--
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
--
G
-------------------
K
----------
L
---
L
----------
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
----
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
---
T
D
H
D
A
I
T
--
K
L
D
---------------------
51
PsiBlast_CBE
86.84
36%
-79
- C9 -
4GAC
2
AK1A1_MOUSE
A:
[7-296]
----------
L
H
-
T
G
Q
K
M
P
L
I
G
L
G
T
W
K
-
S
E
P
G
Q
V
K
A
A
I
K
H
A
L
S
A
G
Y
R
H
I
D
C
A
S
V
Y
G
N
E
T
E
I
G
----
E
----
A
L
------
K
E
S
VGSGK
A
----
V
P
-
R
E
E
L
F
V
T
S
K
L
W
N
T
K
H
H
P
E
D
V
E
--
P
A
L
R
K
T
L
A
D
L
Q
L
E
Y
L
D
L
Y
L
M
H
W
--
P
Y
A
F
E------------------
R
--------------------
G
--
D
--------------------
N
--
P
F
PKNADG
T
V
R
Y
D
STH
Y
K
E
T
W
K
A
L
E
V
L
V
A
K
G
L
V
K
A
L
G
L
S
N
F
N
S
R
Q
I
D
D
V
--
L
S
V
A
--
S
V
R
--
P
A
V
L
Q
V
E
C
H
P
Y
L
A
Q
N
E
L
I
A
H
C
H
A
R
G
L
E
V
T
A
Y
S
P
L
--
G
-------
S
S
----------
D
RAWRHPDEPV
L
---
L
----------
E
E
P
V
V
L
A
L
A
E
K
H
G
R
S
P
A
Q
I
L
L
R
W
Q
V
Q
----
R
K
V
I
C
I
P
K
S
I
N
P
S
R
I
L
Q
N
I
Q
V
F
D
F
T
F
S
P
---
E
E
M
K
Q
L
D
--
A
L
N
K
N
W
---
R
--------------
8
PsiBlast_PDB
86.61
45%
-82
- C9 -
3O0K
4
?
A:
[28-283]
-------
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
E
A
V
-
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
----
A
I
------
N
G
S
-----
G
----
I
A
-
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
--
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
W
--
P
MP--------------------
S
--------------------
K
--
D
--------------------
L
--
F
M
----------------
E
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
--
I
K
E
S
--
G
V
T
--
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
--
G
-------
Q
G
---------------------
L
---
L
----------
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
----
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
---
T
D
H
D
A
I
T
--
K
L
D
---------------------
55
PsiBlast_CBE
86.42
36%
-81
- C9 -
3H7U
2
AKRC9_ARATH
A:
[28-318]
--------
F
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
-
P
G
L
V
G
D
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
A
V
L
K
K
----
L
F
------
E
D
R
-----
V
----
V
K
-
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
--
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
W
--
P
A
R
I
K
K
GSVGI------------
K
--------------------
P
--
E
--------------------
N
--
L
L
PVD
I
P
-----------
S
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
T
K
K
L
A
D
L
--
L
E
L
A
--
R
V
P
--
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
K
G
V
H
L
S
A
Y
S
P
L
--
G
-------
S
P
----------
G
TTWLKSD---
V
---
L
----------
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
----
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
Y
M
F
A
K
F
A
E
I
E
Q
A
R
L
V
T
G
S
---
F
L
V
H
-----------
49
PsiBlast_CBE
86.18
36%
-80
- C9 -
3CV7
5
AK1A1_PIG
A:
[8-300]
----------
L
H
-
T
G
Q
K
M
P
L
I
G
L
G
T
W
K
-
S
E
P
G
Q
V
K
A
A
I
K
Y
A
L
T
V
G
Y
R
H
I
D
C
A
A
I
Y
G
N
E
L
E
I
G
----
E
----
A
L
Q
E
T
VG-
P
G
K
-----
A
----
V
P
-
R
E
E
L
F
V
T
S
K
L
W
N
T
K
H
H
P
E
D
V
E
--
P
A
L
R
K
T
L
A
D
L
Q
L
E
Y
L
D
L
Y
L
M
H
W
--
P
Y
A
F
E------------------
R
--------------------
G
--
D
--------------------
N
--
P
F
P
K
N
ADG
T
I
R
Y
D
ATH
Y
K
D
T
W
K
A
L
E
A
L
V
A
K
G
L
V
R
A
L
G
L
S
N
F
S
S
R
Q
I
D
D
V
--
L
S
V
A
--
S
V
R
--
P
A
V
L
Q
V
E
C
H
P
Y
L
A
Q
N
E
L
I
A
H
C
Q
A
R
G
L
E
V
T
A
Y
S
P
L
--
G
-------
S
S
----------
D
RAWRDPNEPV
L
---
L
----------
E
E
P
V
V
Q
A