@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2775: (2016-04-07 )
MKKFLSIIILVTLIIGNVMFFNFISNTLSRDFLFKEQTVVQFKYKEDYQVSDFNNSIKTFSETKNINIAQYTFLGERDLNIYGSNCQFAPNINLKKGDYPNKNQFLANEESVDKKQSGVIYHPSKYWSLKVYDFGQIKNVGLSDTFYVSGLDNQNTYQAFLKEFEQYGEVTTKSVDVSWWKYINIPLLMTLLLCFAILFVFTYYYLRYSKQRLLVNRIWGNSELVTLMSLFNKTIIFTLFSVLAILITFVSIVLANGLATYLVEIVWKLLLFNVLLFIFILFPMYFFGLLRIKKIDQAKSDQRMQSSRQHLAINLVIKFVLLCLFIGTFIASYQSLQTLNTRLANIDVWEATKDIFKVKVGVLPEGIQDDLKADKELNDNLSAFYEEGTSKKEMFLMYSNNFQRSETNTFFYETYLKKGSEINSPEGNSVEIDFNYLKLNPIKSIKGQNVGKEAIISDKVLNIIVPNSKKGLEKDIKNTFLDYFYFQKVEVANIYNEALDLPAVALSKEDLRVNIIYAENNQDYFSYDSNTGDFRTGNITDPIAIVYTGNIDSSSIGAHVTSSVYFVDKSNGDAFNAILPLISNSNAREITHVRSVYQEVSSEITTLKWQIYQQLIGTIILALCLCSFMVLLVLSYYRENLYKQLIYHVFGYSFWKSSKWFIISNLFVSVFSGILIFILSKEPVALYFSVVILIIELCAIYFIKEKAIYKDFKAILKGEKYD
Atome Classification :
(20 SA)
.........10........20........30........40..---....--..50.......----.60........70........80........90....-----------....100.......110.......120-........130.......140....-----...150.......160.-......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380-......-..390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510........520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
K
F
L
S
I
I
I
L
V
T
L
I
I
G
N
V
M
F
F
N
F
I
S
N
T
L
S
R
D
FLFKE
Q
T
V
V
Q
F
K
---YKED--YQVSDFNN
S
I
K
----TFSETKN
I
N
I
A
Q
Y
T
F
LGER
D
L
N
I
YGSN
C
Q
FAPNINLK-----------KGDYPNKNQFLANEESVDKKQS
G
V
I
Y--HPS
K
Y
W
S
L
K
V
Y
DFGQIKNVGLS
D
T
F
-----
Y
V
SGLDN
Q
N
T
Y
Q
A
F
L
K
E
-
F
E
Q
YGEVTTKSVD
V
S
W
W
K
YI
N
I
P
L
L
M
T
L
L
L
C
F
A
I
L
F
V
F
T
Y
Y
Y
L
R
Y
S
K
Q
R
L
L
V
N
R
IWGN
S
E
L
V
T
L
M
S
L
FN
K
T
I
I
F
T
L
F
S
V
L
A
I
L
I
T
F
V
S
I
V
L
AN
G
L
A
T
Y
L
V
E
I
V
W
K
L
L
L
F
N
V
L
L
F
I
F
I
L
F
P
M
Y
F
F
G
L
L
R
I
K
K
I
D
QAK
S
D
Q
R
M
Q
S
S
R
Q
H
L
A
I
N
L
V
I
K
F
V
L
L
C
L
F
I
G
T
F
I
A
S
Y
Q
S
L
Q
T
L
N
T
RLANI
D
V
W
E
A
T
K
D
I
F
K
V
K
VGVLPE
G
I
Q
D
D
L
K
ADKELN
D
N
-
L
-
S
A
F
Y
E
E-GTSK
K
E
M
F
L
M
YSNNFQRSETN
T
F
F
Y
E
T
Y
L
KKGSEINSPEG
N
S
V
E
I
D
F
N
Y
L
K
LNP
I
K
S
IKGQNVG
K
E
AIISD
K
V
L
N
I
I
VPNSKK
G
L
E
K
D
I
K
N
T
F
L
D
Y
F
Y
F
Q
K
V
E
V
A
N
I
Y
N
E
ALDLPAVALSKE
D
L
-
R
V
N
I
I
Y
AENNQ
D
Y
F
SYDSNTGDFRTGNITD
P
I
A
I
V
Y
TGNIDSSSIG
A
H
V
T
S
S
V
Y
F
V
DKSNG
D
A
F
N
A
I
L
P
LISNSN
A
R
E
I
T
H
V
R
S
V
Y
Q
E
V
S
S
E
I
T
T
L
K
W
Q
I
Y
Q
Q
L
I
G
T
I
I
L
A
L
C
L
C
S
F
M
V
L
L
V
L
S
Y
Y
R
E
N
L
Y
K
Q
L
I
Y
H
V
F
G
Y
S
FWKSS
K
W
F
I
I
S
N
L
F
V
S
V
F
S
G
I
L
I
F
I
LSKE
P
V
A
L
Y
F
S
V
V
I
L
I
I
E
L
C
A
I
Y
F
I
K
E
K
A
I
Y
K
D
F
K
A
I
LKGEKYD------
15
Fugue
87.74
15%
-64
- C2 -
1UWK
2
HUTU_PSEPU
A:
[4-557]
N
N
K
Y
R
D
V
E
I
R
A
P
R
-----------
G
N
K
L
T
A
K
S
W
L
T
E
A
P
L
R
M
L
M
---
N
N
L
D
--
P
Q
V
A
E
N
--------------------------
P
K
E
L
V
V
Y
G
G
I
G
R
A
A
------------------
R
N
W
E
C
Y
D
K
I
V
E
T
L
T
R
L
E
D
D
E
T
L
L
V
Q
SG
K
P
V
G
V
F
K
----
T
H
S
N
A
P
R
V
L
I
A
N
S
N
-----
L
V
P
H
W
A
N
W
E
H
F
N
E
L
D
A
K
G
L
A
M
Y
G
Q
M
T
-----
A
G
S
W
I
Y
I
G
S
----------
Q
G
I
V
Q
G
T
Y
E
T
F
V
E
A
G
R
Q
H
Y
G
G
S
L
K
G
K
------------------------------
W
V
L
T
A
G
L
G
G
M
G
G
A
Q
P
L
A
A
T
L
A
G
A
C
S
L
N
I
E
S
Q
Q
S
R
I
D
F
R
L
E
T
R
Y
V
D
E
Q
A
T
D
--
L
D
D
A
L
V
R
I
A
K
Y
T
A
E
G
K
A
I
S
I
A
L
H
G
N
A
A
E
I
L
P
E
L
V
K
R
G
V
R
P
D
M
V
T
D
Q
T
S
A
H
D
P
L
N
---
G
Y
L
P
A
G
-
W
T
W
E
Q
Y
R
D
R
A
Q
T
E
-
P
-
A
A
V
V
K
A
-
A
K
Q
S
M
A
V
H
V
Q
A
M
L
D
F
Q
K
Q
G
V
P
T
F
D
Y
G
N
N
I
R
Q
M
A
K
E
E
G
V
A
-----------
D
A
F
D
F
P
G
F
V
P
A
Y
I
R
P
L
F
C
R
G
V
G
P
F
R
W
A
A
L
S
---
G
E
A
E
D
I
Y
K
T
--
D
A
K
V
K
E
L
I
P
D
D
A
H
L
H
R
W
L
D
M
A
R
E
R
I
S
F
Q
G
L
-
P
A
R
I
C
W
V
G
L
G
L
R
A
K
L
G
L
A
F
N
E
M
V
R
S
G
E
L
S
A
P
V
V
I
G
R
D
-
H
L
D
S
G
S
V
S
S
P
N
A
E
T
E
A
M
R
D
G
S
D
A
V
S
D
W
P
L
L
N
A
L
L
N
T
A
G
-----------------------------
G
A
T
W
V
S
L
H
H
G
G
-----------------------
G
V
G
M
G
F
S
------------
Q
H
S
G
M
V
I
V
C
D
G
T
D
E
A
A
E
R
I
A
R
V
L
T
N
D
P
G
T
G
V
M
R
H
A
D
-
A
G
Y
D
I
A
I
D
C
A
K
E
Q
G
L
D
LPMITG
1
PsiBlast_PDB
39.52
30%
243
- C3 -
3NEH
2
?
A:
[249-290]
--------------------------------------------------------------------------------------------------------------------------------------------------------
I
C
E
L
G
G
L
K
N
I
G
F
G
S
D
F
DGIPD
H
V
K
G
L
E
H
V
G
K
Y
Q
S
F
L
E
T
-
L
E
K
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
37.17
28%
165
- C3 -
1OYS
-
RNPH_BACSU
A:
[175-230]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
G
S
G
R
F
V
E
L
Q
G
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
36.94
19%
231
- C3 -
2CPG
1
COPG_STRAG
A:
[1-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
R
L
T
I
T
L
S
E
S
V
L
E
N
-
L
-
E
K
M
A
R
E
M
G
L
S
K
S
A
M
I
S
V
A
L
E
N
Y
K
K
G
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
36.55
28%
161
- C3 -
1OYR
2
RNPH_BACSU
A:
[175-230]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
G
S
G
R
F
V
E
L
Q
G
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
36.48
16%
588
* C3 *
1VYT
-
CAC1C_RAT
E:
[1-25]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
L
R
E
K
Q
Q
L
E
E
D
-
L
-
K
G
Y
L
D
W
-
I
T
Q
A
E
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
36.44
28%
165
- C3 -
1OYP
-
RNPH_BACSU
A:
[175-230]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
N
Y
E
E
D
S
S
A
E
V
D
M
N
V
I
M
T
G
S
G
R
F
V
E
L
Q
G
T
G
E
E
A
T
F
S
R
E
D
L
N
G
L
L
G
L
A
E
K
G
I
Q
E
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
30.75
20%
89
- C3 -
3UAU
-
?
A:
[128-272]
------------------------
S
N
L
V
F
E
D
F
K
L
G
E
K
V
V
S
D
I
N
A
S
L
F
Q
Q
D
--
P
K
I
S
S
F
I
N
K
L
S
S
D
S
Y
T
L
S
F
D
N
S
I
N
K
Q
E
N
N
Y
L
D
N
L
D
I
K
F
Y
N
A
K
L
N
F
N
T
N
L
N
I
N
L
K
E
D
L
L
N
Y
L
D
S
K
G
I
K
F
N
T
Q
T
L
A
M
D
E
Q
A
I
N
E
L
L
N
---------
S
D
F
S
N
T
I
Q
K
Y
I
I
L
N
N
F
K
I
D
S
T
L
-----
K
T
E
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
29.48
11%
285
- C3 -
3IS6
1
?
A:
[76-119]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
E
T
K
T
L
L
A
E
P
A
F
L
D
M
F
G
V
E
L
I
A
G
V
R
D
S
A
----
L
R
D
N
M
T
C
L
I
S
E
S
L
A
R
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
28.50
35%
208
- C3 -
2RB7
-
?
A:
[200-247]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
D
L
L
M
E
D
Y
T
R
L
K
T
L
F
A
E
E
N
E
D
H
W
H
R
T
V
N
L
G
R
I
R
A
G
E
S
T
N
K
V
P
D
V
A
E
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
28.09
9%
332
- C3 -
2JNA
-
?
A:
[40-76]
--------------------------------------
T
I
N
V
S
---
Q
S
G
G
QI
S
S
P
S
D
L
R
E
K
L
S
----
E
L
A
D
A
K
G
G
K
Y
Y
H
I
I
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
27.69
23%
497
- C3 -
1G2Z
-
HNF1A_MOUSE
B:
[2-32]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
K
L
S
Q
L
Q
T
E
-
L
M
A
A
L
L
E
S
-
G
L
S
K
E
A
L
I
Q
A
L
G
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
27.36
22%
503
- C3 -
1G2Z
-
HNF1A_MOUSE
A:
[1-32]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
T
E
-
L
M
A
A
L
L
E
S
-
G
L
S
K
E
A
L
I
Q
A
L
G
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
27.25
24%
576
- C3 -
1G2Y
-
HNF1A_MOUSE
B:
[1-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
T
E
M
L
-
A
A
L
L
E
S
-
G
L
S
K
E
A
L
I
Q
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
27.06
23%
509
- C3 -
1G2Y
-
HNF1A_MOUSE
A:
[1-31]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
T
E
M
L
-
A
A
L
L
E
S
-
G
L
S
K
E
A
L
I
Q
A
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
26.75
24%
561
- C3 -
1G2Y
-
HNF1A_MOUSE
D:
[1-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
K
L
S
Q
L
Q
T
E
M
L
-
A
A
L
L
E
S
-
G
L
S
K
E
A
L
I
Q
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
24.48
9%
344
- C3 -
2NOC
-
?
A:
[42-74]
--------------------------------------
T
I
S
T
T
---
G
E
-
M
---
S
P
L
D
A
R
E
D
L
I
----
K
K
A
D
E
K
G
A
D
V
V
V
L
T
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
21.14
15%
573
- C3 -
2L69
-
?
A:
[34-59]
-----------------------------------------------------
S
P
Q
E
L
K
D
S
I
E
----
E
L
V
K
K
Y
N
A
T
I
V
V
V
V
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
19.31
11%
528
- C3 -
2LN3
-
?
A:
[37-63]
------------------------------------------------
D
D
--
K
E
I
E
E
F
E
R
D
M
E
----
D
L
A
K
K
T
G
V
Q
I
Q
K
Q
W
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
16.23
11%
2077
- C1 -
1AFO
-
GLPA_HUMAN
A:
[92-100]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
G
I
R
R
L
I
K
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