@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2821: (2016-04-07 )
LKTTKIVIASLVSLTMVSNPLLTFAATNDVIDNTTEITTDKETSSTQPTIKNTLKAGQTQSFNDWFPDDNFASEVAAAFEMQATDTISEEQLATLTSLDCHNSSITDMTGIEKLTGLTKLICTSNNITTLDLSQNTNLTYLACDSNKLTNLDVTPLTKLTYLNCDTNKLTKLDVSQNPLLTYLNCARNTLTEIDVSHNTQLTELDCHLNKKITKLDVTPQTQLTTLDCSFNKITELDVSQNKLLNRLNCDTNNITKLDLNQNIQLTFLDCSSNKLTEIDVTPLTQLTYFDCSVNPLTELDVSTLSKLTTLHCIQTDLLEIDLTHNTQLIYFQAEGCRKIKELDVTHNTQLYLLDCQAAGITELDLSQNPKLVYLYLNNTELTELDVSHNTKLKSLSCVNAHIQDFSSVGKIPALNNNFEAEGQTITMPKETLTNNSLTIAVSPDLLDQFGNPMNIEPGDGGVYDQATNTITWENLSTDNPAVTYTFTSENGAIVGTVTTPFEAPQPIKGEDVTVHYLDDKGEKLADDEVLSGNLDDPYTSSAKDIPDYTLTTTPDNATGTFTTTSQSVTYVYTKNIVAAEPVTVNYVDDTGKTLSPSEILNGNVGDTYNATAKQIDGYTLSAEPTNATGQFTSSAQTVNYIYTKNPAPEKGVVEIHYVDEDNKQLNSTTEISGTIGDNYTTEPKTIEGYTLTTTPGNATGTFTTGSQTVTYVYTKNIEAAEPITVNYVDANGKTLAPSETLNGNVGDTYKATAKQIDGYTLSAEPTNATGQFTSSAQTVNYIYTKNTNTDQPLPTKKPTNTTPTKPSNLKTTEVKKASDTLPKTGDSAPWKSALLGVFLSSTALVIWKKKK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........-80..-.-......90........100.......110.........120.......130--........140---.......150-------------------.---...---.---...160--.......-.170-.---......180..---.....190.-.---.....200..-.-....210.........220----.......---..230..-..-.---..240..-----.....250......-.260.-......270.......---280.......290........---300.......310.......320-....-...330.-----------......340----.....--------------..350.......360.......370.......--------380..---.-....390.........400.......410.......420.......430.......440.......--450..------------------....---.460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
LKT
T
K
I
V
I
A
S
L
V
S
L
T
MVSNP
L
L
T
F
AATNDVIDNTTEITTDKETSSTQ
P
T
I
K
N
T
L
KAGQTQSFNDWFPDD
N
F
A
S
E
V
A
A
A
F
-E-MQ-A-TDTI
S
E
E
Q
L
A
T
L
TSLDCHNSSITDMT
G
--
I
E
K
L
T
G
L
T
K
L
I
CTSN
N
I
T
T
L
D
---LSQNT
N
L
T
Y
L
A
---CDSNKLTNL--------------------D---VTP---
L
---
T
K
L
T
Y
---
L
NCDTN
K
-
L
T
K
L-D---VSQN
P
L
L
T
Y
L
N
---
C
ARNT
L
T
E
I
-D---VSHNT
Q
L
T
E
L
-
D
-
C
HLNK--
K
I
T
K
LDVTPQ------T
Q
L
T
T
L
D---CSFNK
I
T
-EL-D---V
S
Q
N
K
L
L
-----
N
R
LNCDTN
N
I
T
K
L
D-LNQN
I
-
Q
L
T
F
L
DCSSN
K
L
T
E
I
D---VTP
L
T
Q
L
T
Y
F
D-CSVNP
L
T
E
L
---
D
V
S
T
L
S
K
L
T
T
L
H
C
IQT
D
L
L
E
I
D
L-THN
T
-
Q
L
I
Y
F
QA-----------EGC
R
K
I
K
E
L----DVTHN--------------
T
Q
L
Y
L
L
DCQAAG
I
T
E
LDLSQNP
K
L
V
Y
L
Y
LNNT--------
E
L
T
E
L
---D-VSHNT--KLKS
L
S
C
V
N
A
H
I
Q
D
F
S
SVGKIPALNNNFEAEG
Q
T
I
TM
P
K
ETLTNN
S
L
T
I
A
V
S
P
D
L
L
D
QF--GNPMN------------------IEPG---DGGVYDQAT
N
T
I
T
W
ENLSTDN
P
A
V
T
Y
T
F
TSEN
G
A
I
V
G
T
VTTPFEAPQPIKGE
D
V
T
V
H
Y
LDDKGEKLADDEVLSGNLDDPYTSSAKDIPD
Y
T
L
TTTPDNA
T
G
T
F
T
TTS
Q
S
V
T
Y
V
Y
TKNIVAAE
P
V
T
V
N
Y
VDDTGKTL
S
P
S
E
ILNGNVGDTYNA
T
A
K
QID
G
Y
T
LSAEPTNATGQFTSS
A
Q
T
V
N
Y
I
Y
TKNPAPEK
G
V
V
E
I
H
Y
VDEDNKQLNSTT
E
I
S
G
TIGDNYTTE
P
K
T
IE
G
Y
T
L
TTTPGN
A
T
G
T
F
TTG
S
Q
T
V
T
Y
V
Y
TKNIEAAE
P
I
T
V
N
Y
VDANGKTLAPSETLNGNVGD
T
Y
K
A
T
A
K
QID
G
Y
T
LSAEPTNATGQFTSS
A
Q
T
V
N
Y
I
Y
TKNTNTDQPLPTKKPTNTTPTKPSNLKT
T
E
VKKASDTLPKTGDSA
P
W
K
S
A
L
L
G
V
F
LSS
T
A
L
V
I
W
KKKK
35
Fugue
97.44
100%
-104
- C1 -
3BZ5
2
INLJ_LISMO
A:
[2-451]
----------------------------------------------------
T
L
K
A
G
Q
T
Q
S
F
N
D
W
F
P
D
D
N
F
A
S
E
V
A
A
A
F
-
E
-
M
Q
-
A
-
T
D
T
I
S
E
E
Q
L
A
T
L
T
S
L
D
C
H
N
S
S
I
T
D
M
T
G
--
I
E
K
L
T
G
L
T
K
L
I
C
T
S
N
N
I
T
T
L
D
---
L
S
Q
N
T
N
L
T
Y
L
A
---
C
D
S
N
K
L
T
N
L
--------------------
D
---
V
T
P
---
L
---
T
K
L
T
Y
---
L
N
C
D
T
N
K
-
L
T
K
L
-
D
---
V
S
Q
N
P
L
L
T
Y
L
N
---
C
A
R
N
T
L
T
E
I
-
D
---
V
S
H
N
T
Q
L
T
E
L
-
D
-
C
H
L
N
K
--
K
I
T
K
L
D
V
T
P
Q
------
T
Q
L
T
T
L
D
---
C
S
F
N
K
I
T
-
E
L
-
D
---
V
S
Q
N
K
L
L
-----
N
R
L
N
C
D
T
N
N
I
T
K
L
D
-
L
N
Q
N
I
-
Q
L
T
F
L
D
C
S
S
N
K
L
T
E
I
D
---
V
T
P
L
T
Q
L
T
Y
F
D
-
C
S
V
N
P
L
T
E
L
---
D
V
S
T
L
S
K
L
T
T
L
H
C
I
Q
T
D
L
L
E
I
D
L
-
T
H
N
T
-
Q
L
I
Y
F
Q
A
-----------
E
G
C
R
K
I
K
E
L
----
D
V
T
H
N
--------------
T
Q
L
Y
L
L
D
C
Q
A
A
G
I
T
E
L
D
L
S
Q
N
P
K
L
V
Y
L
Y
L
N
N
T
--------
E
L
T
E
L
---
D
-
V
S
H
N
T
--
K
L
K
S
L
S
C
V
N
A
H
I
Q
D
F
S
S
V
G
K
I
P
A
L
N
N
N
F
E
A
E
G
Q
T
I
T
M
P
K
E
T
L
T
N
N
S
L
T
I
A
V
S
P
D
L
L
D
Q
F
--
G
N
P
M
N
------------------
I
E
P
G
---
D
G
G
V
Y
D
Q
A
T
N
T
I
T
W
E
N
L
S
T
D
N
P
A
V
T
Y
T
F
T
S
E
N
G
A
I
V
G
T
V
T
T
P
F
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
97.35
100%
-104
- C1 -
3BZ5
2
INLJ_LISMO
A:
[2-451]
----------------------------------------------------
T
L
K
A
G
Q
T
Q
S
F
N
D
W
F
P
D
D
N
F
A
S
E
V
A
A
A
F
-
E
-
M
Q
-
A
-
T
D
T
I
S
E
E
Q
L
A
T
L
T
S
L
D
C
H
N
S
S
I
T
D
M
T
G
--
I
E
K
L
T
G
L
T
K
L
I
C
T
S
N
N
I
T
T
L
D
---
L
S
Q
N
T
N
L
T
Y
L
A
---
C
D
S
N
K
L
T
N
L
--------------------
D
---
V
T
P
---
L
---
T
K
L
T
Y
---
L
N
C
D
T
N
K
-
L
T
K
L
-
D
---
V
S
Q
N
P
L
L
T
Y
L
N
---
C
A
R
N
T
L
T
E
I
-
D
---
V
S
H
N
T
Q
L
T
E
L
-
D
-
C
H
L
N
K
--
K
I
T
K
L
D
V
T
P
Q
------
T
Q
L
T
T
L
D
---
C
S
F
N
K
I
T
-
E
L
-
D
---
V
S
Q
N
K
L
L
-----
N
R
L
N
C
D
T
N
N
I
T
K
L
D
-
L
N
Q
N
I
-
Q
L
T
F
L
D
C
S
S
N
K
L
T
E
I
D
---
V
T
P
L
T
Q
L
T
Y
F
D
-
C
S
V
N
P
L
T
E
L
---
D
V
S
T
L
S
K
L
T
T
L
H
C
I
Q
T
D
L
L
E
I
D
L
-
T
H
N
T
-
Q
L
I
Y
F
Q
A
-----------
E
G
C
R
K
I
K
E
L
----
D
V
T
H
N
--------------
T
Q
L
Y
L
L
D
C
Q
A
A
G
I
T
E
L
D
L
S
Q
N
P
K
L
V
Y
L
Y
L
N
N
T
--------
E
L
T
E
L
---
D
-
V
S
H
N
T
--
K
L
K
S
L
S
C
V
N
A
H
I
Q
D
F
S
S
V
G
K
I
P
A
L
N
N
N
F
E
A
E
G
Q
T
I
T
M
P
K
E
T
L
T
N
N
S
L
T
I
A
V
S
P
D
L
L
D
Q
F
--
G
N
P
M
N
------------------
I
E
P
G
---
D
G
G
V
Y
D
Q
A
T
N
T
I
T
W
E
N
L
S
T
D
N
P
A
V
T
Y
T
F
T
S
E
N
G
A
I
V
G
T
V
T
T
P
F
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
96.77
100%
-105
- C1 -
3BZ5
2
INLJ_LISMO
A:
[6-451]
--------------------------------------------------------
G
Q
T
Q
S
F
N
D
W
F
P
D
D
N
F
A
S
E
V
A
A
A
F
-
E
-
M
Q
-
A
-
T
D
T
I
S
E
E
Q
L
A
T
L
T
S
L
D
C
H
N
S
S
I
T
D
M
T
G
--
I
E
K
L
T
G
L
T
K
L
I
C
T
S
N
N
I
T
T
L
D
---
L
S
Q
N
T
N
L
T
Y
L
A
---
C
D
S
N
K
L
T
N
L
--------------------
D
---
V
T
P
---
L
---
T
K
L
T
Y
---
L
N
C
D
T
N
K
-
L
T
K
L
-
D
---
V
S
Q
N
P
L
L
T
Y
L
N
---
C
A
R
N
T
L
T
E
I
-
D
---
V
S
H
N
T
Q
L
T
E
L
-
D
-
C
H
L
N
K
--
K
I
T
K
L
D
V
T
P
Q
------
T
Q
L
T
T
L
D
---
C
S
F
N
K
I
T
-
E
L
-
D
---
V
S
Q
N
K
L
L
-----
N
R
L
N
C
D
T
N
N
I
T
K
L
D
-
L
N
Q
N
I
-
Q
L
T
F
L
D
C
S
S
N
K
L
T
E
I
D
---
V
T
P
L
T
Q
L
T
Y
F
D
-
C
S
V
N
P
L
T
E
L
---
D
V
S
T
L
S
K
L
T
T
L
H
C
I
Q
T
D
L
L
E
I
D
L
-
T
H
N
T
-
Q
L
I
Y
F
Q
A
-----------
E
G
C
R
K
I
K
E
L
----
D
V
T
H
N
--------------
T
Q
L
Y
L
L
D
C
Q
A
A
G
I
T
E
L
D
L
S
Q
N
P
K
L
V
Y
L
Y
L
N
N
T
--------
E
L
T
E
L
---
D
-
V
S
H
N
T
--
K
L
K
S
L
S
C
V
N
A
H
I
Q
D
F
S
S
V
G
K
I
P
A
L
N
N
N
F
E
A
E
G
Q
T
I
T
M
P
K
E
T
L
T
N
N
S
L
T
I
A
V
S
P
D
L
L
D
Q
F
--
G
N
P
M
N
------------------
I
E
P
G
---
D
G
G
V
Y
D
Q
A
T
N
T
I
T
W
E
N
L
S
T
D
N
P
A
V
T
Y
T
F
T
S
E
N
G
A
I
V
G
T
V
T
T
P
F
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
69.03
38%
-68
* C1 *
3BZ5
1
INLJ_LISMO
A:
[38-355]
--------------------------------------------------------------------------------------------------------------------
E
E
Q
L
A
T
L
T
S
L
D
C
H
N
S
S
I
T
D
M
T
G--
I
E
K
L
T
G
L
T
K
L
I
---
C
T
S
N
N
I
T
T
L
--------------------
D
---
L
S
Q
---
N
---
T
N
L
T
Y
---
L
A
C
D
S
N
K
-
L
T
N
L
-
D
---
V
T
P
L
T
K
L
T
Y
L
N
---
C
D
T
N
K
L
T
K
L
-
D
---
V
S
Q
N
P
L
L
T
Y
L
-
N
-
C
A
R
N
T
--
L
T
E
I
-
D
V
S
H
N
------
T
Q
L
T
E
L
D
---
C
H
L
N
K
K
I
T
K
L
-
D
---
V
T
P
Q
T
Q
L
-----
T
T
L
D
C
S
F
N
K
I
T
E
L
D
-
V
S
Q
N
K
-
L
L
N
R
L
N
C
D
T
N
N
I
T
K
L
D
---
L
N
Q
N
I
Q
L
T
F
L
D
-
C
S
S
N
K
L
T
E
I
---
D
V
T
P
L
T
Q
L
T
Y
F
D
C
S
V
N
P
L
T
E
L
D
V
-
S
T
L
S
-
K
L
T
T
L
H
C
-----------
I
-
Q
T
D
L
L
E
I
----
D
L
T
H
N
--------------
T
----------
Q
L
I
Y
F
Q
A
E
G
C
R
K
I
K
E
L
D
V
T
H
N
TQLYLLDC
Q
A
A
G
I
TEL
D
-
L
S
Q
N
P
--
K
L
V
Y
L
Y
L
N
N
T
E
L
T
E
L
D
-
V
S
H
N
T
K
L
K
S
L
S
C
V
N
A
H
I
Q
D
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
65.82
29%
-64
- C1 -
2OMU
2
INLA_LISMO
A:
[9-462]
-------------------------------------------------------------
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
D
I
-
S
A--
L
S
G
L
T
S
L
Q
Q
L
-
S
-
F
S
S
N
Q
--
V
T
---
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
YKA
N
V
S
I
P
NTVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.69
29%
-62
- C1 -
2OMX
2
INLA_LISMO
A:
[5-462]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
D
I
-
S
A--
L
S
G
L
T
S
L
Q
Q
L
-
N
-
F
S
S
N
Q
--
V
T
---
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
YKA
N
V
S
I
P
NTVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
65.15
24%
-87
- C1 -
1O6V
1
INLA_LISMO
A:
[9-391]
--------------------------------------------------------
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
-
G
-
K
T
N
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P--
L
K
N
L
T
K
L
V
D
I
L
---
M
N
N
N
Q
I
A
D
I
--------------------
T
P--
L
A
N
---
L
---
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
D
P
---
L
K
N
L
T
N
L
N
R
L
E
---
L
S
S
N
T
I
S
D
I
-
S
A--
L
S
G
L
T
S
L
Q
Q
L
-
S
-
F
G
N
Q
---
V
T
D
L
K
P
L
A
N
L
------
T
T
L
E
R
L
D
---
I
S
S
N
K
V
S
-
D
I
-
S
V
--
L
A
K
L
T
N
L
-----
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
L
T
-
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T--
L
A
S
L
T
N
L
T
D
L
D
-
L
A
N
N
Q
I
S
N
L
A--
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
-
A
L
T
N
L
E
L
-----------
N
E
N
-
Q
L
E
D
I
SPIS
N
L
K
N
L
--------------
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
--
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
--------
K
V
S
D
V
---
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
64.87
29%
-63
- C1 -
2OMZ
-
INLA_LISMO
A:
[40-496]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
LAN
L
---
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
Q
Q
-
L
S
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
A
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
YKAN
V
S
I
P
NTVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
--
D
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
64.73
29%
-65
- C1 -
2OMW
5
INLA_LISMO
A:
[5-461]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
N
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
YKA
N
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
62.62
29%
-55
- C- -
2OMY
5
INLA_LISMO
A:
[5-461]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
N
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
AN
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.37
29%
-49
- C- -
2OMT
2
INLA_LISMO
A:
[5-462]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
D
I
-
S
A--
L
S
G
L
T
S
L
Q
Q
L
-
S
-
F
S
S
N
Q
--
V
T
---
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
AN
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
62.08
29%
-55
- C- -
2OMV
3
INLA_LISMO
A:
[5-461]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
N
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
YKAN
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
61.98
29%
-54
- C- -
1O6T
11
INLA_LISMO
A:
[10-466]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
DIL
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
S
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.51
29%
-53
- C- -
1O6V
1
INLA_LISMO
A:
[10-466]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
S
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
TVKNVTG
A
L
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
61.40
29%
-56
- C- -
1O6S
4
INLA_LISMO
A:
[10-466]
---------------------------------------------------------
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
-
T
N
-
V
-
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
--
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
--
D
---
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
----------------------
D
---
I
T
P
---
L
ANL
T
N
L
T
G
---
L
T
L
F
N
N
Q
-
I
T
D
I
-
D
---
P
L
K
N
--
L
T
N
L
N
R
L
E
L
S
S
N
T
I
S
---
D
---
I
S
A
L
S
G
L
T
S
L
-
Q
Q
L
S
F
G
N
--
Q
V
T
--
D
L
K
P
L
------
A
N
L
T
T
L
E
-----------
R
L
-
D
---
I
S
S
N
K
V
----------
S
D
I
S
V
L
A
K
L
------
T
-
N
L
E
S
L
I
A
T
N
N
Q
I
S
--
D
---
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
---
D
I
G
T
L
A
S
L
T
N
L
----
T
D
L
---
D
L
-
A
N
N
Q
-
I
S
N
L
A
P
L
-----------
S
G
L
T
K
L
T
E
L
----
K
L
G
A
N
QISNISPLAGLTAL
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
----------
I
S
D
I
---
S
P
V
S
S
L
T
--
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
--
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
--
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
AN
V
S
I
P
NTVKNVTGAL
I
A
P
A
TIS
D
G
G
S
Y
T
E
P
D
--
I
T
W
-
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
58.92
23%
-82
- C1 -
1O6V
1
INLA_LISMO
A:
[64-391]
--------------------------------------------------------------------------------------------
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
--
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P--
L
A
N
L
T
N
L
T
G
L
T
---
L
F
N
N
Q
I
T
D
I
--------------------
D
P--
L
K
N
---
L
---
T
N
L
N
R
---
L
E
L
S
S
N
T
-
I
S
D
I
S
A
---
L
S
G
L
T
S
L
Q
Q
L
S
---
F
G
N
Q
V
T
D
L
K
-
P
---
L
A
N
L
T
T
L
E
R
L
-
D
-
I
S
S
N
K
--
V
S
D
I
S
V
L
A
K
L
------
T
N
L
E
S
L
I
---
A
T
N
N
Q
I
S
-
D
I
-
T
P--
L
G
I
L
T
N
L
-----
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
-
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P--
L
S
G
L
T
K
L
T
E
L
K
-
L
G
A
N
Q
I
S
N
I
S--
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
-
N
L
T
Y
L
T
L
YFNNISDISPV
S
S
L
T
K
L
Q
--------------------------
R
L
F
F
Y
N
N
K
V
S
D
V
S
--
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
--------
Q
I
S
D
L
---
T
P
L
A
N
L
T
--
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
55.80
28%
-88
- C1 -
4FMZ
5
?
A:
[12-292]
-------------------------------------------------------------
I
N
Q
I
F
P
D
A
D
L
A
E
G
I
R
A
V
L
-
Q
K
A
S
-
V
-
T
D
V
V
T
Q
E
E
L
E
S
I
T
K
L
V
V
A
G
E
K
V
A
S
I
Q
G
--
I
E
Y
L
T
N
L
E
Y
L
N
L
N
G
N
Q
I
T
D
I
S
P--
L
S
N
L
V
K
L
T
N
L
Y
---
I
G
T
N
K
I
T
D
I
SALQNLTNLR
E
L
Y
LNEDNIS
D
---
I
S
P
---
L
---
A
N
L
T
K
MY
S
L
N
L
G
A
N
H
N
L
S
D
L
-
S
P--
L
S
N
M
T
G
L
N
Y
L
T
---
V
T
E
S
K
V
K
D
V
T
P
---
I
A
N
L
T
D
L
Y
S
L
-
S
-
L
N
Y
N
Q
-----
I
E
D
I
S
P
L
------
A
S
L
T
S
L
H
Y
F
T
A
Y
V
N
Q
I
T
-
D
I
T
P
---
V
A
N
M
T
R
L
-----
N
S
L
K
I
G
N
N
K
I
T
D
L
S
-
P
L
A
N
L
S
Q
L
T
W
L
E
I
G
T
N
Q
I
S
D
I
N
A--
V
K
D
L
T
K
L
K
M
L
N
-
V
G
S
N
Q
I
S
-----
D
I
S
V
L
N
N
L
S
Q
L
N
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
55.67
32%
-85
- C1 -
4R5C
2
?
A:
[12-275]
-----------------------------------------------------------------
F
P
D
D
A
F
A
E
T
I
K
A
N
L
-
K
-
K
K
-
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
--
I
Q
Y
L
P
N
V
R
Y
L
A
L
G
G
N
K
L
H
D
I
S
A--
L
K
E
L
T
N
L
G
W
L
N
---
L
S
N
N
Q
L
E
T
L
--------------------
P
QGV
F
E
K
---
L
---
T
N
L
T
T
---
L
N
L
S
N
N
Q
-
L
T
S
L
-
P
QGV
F
E
R
L
A
S
L
T
T
L
N
---
L
S
N
N
Q
L
T
S
L
-
P
---
Q
G
V
F
E
R
L
T
N
L
-
T
-
T
-
L
N
L
--
S
N
N
Q
L
T
S
L
P
Q
GVFERL
T
N
L
T
T
L
N
---
L
S
N
N
Q
L
T
-
S
L
-
P
QGV
F
E
R
L
T
S
L
-----
H
T
L
D
L
S
N
N
G
I
T
D
I
S
-
A
L
K
N
L
D
N
L
H
T
L
D
L
S
N
N
G
I
T
D
I
S
A--
L
K
N
L
D
N
L
H
T
L
D
-
L
S
N
N
G
I
T
-----
D
I
S
A
L
K
N
L
T
S
L
H
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
55.59
22%
-72
- C1 -
3OJA
4
?
B:
[51-394]
------------------------------------------------------------------------------------------------
N
N
Q
K
I
V
T
F
K
N
S
T
M
R
K
L
P
A
A
L
L
D
S
F
R
Q
V
E
L
L
N
L
N
D
L
Q
I
E
E
I
D
TYA
F
A
Y
A
H
T
I
Q
K
L
Y
---
M
G
F
N
A
I
R
Y
L
--------------------
P
PHV
F
Q
N
---
V
---
P
L
L
T
V
---
L
V
L
E
R
N
D
-
L
S
S
L
-
P
RGI
F
H
N
T
P
K
L
T
T
L
S
---
M
S
N
N
N
L
E
R
I
-
E
DDT
F
Q
A
T
T
S
L
Q
N
L
-
Q
-
L
S
S
N
R
--
L
T
H
-
V
D
L
S
L
I
------
P
S
L
F
H
A
N
---
V
S
Y
N
L
L
S
-
T
L
-
A
---
I
--
P
I
A
V
-----
E
E
L
D
A
S
H
N
S
I
N
V
V
R
-
G
P
V
N
V
-
E
L
T
I
L
K
L
Q
H
N
N
L
T
D
T
A
W--
L
L
N
Y
P
G
L
V
E
V
D
-
L
S
Y
N
E
L
E
K
I
MYH
P
F
V
K
M
Q
R
L
E
R
L
Y
I
S
N
N
R
L
V
A
L
N
L
-
Y
G
---------------------
Q
P
I
P
T
L
K
V
L
----
D
----------------------
L
S
H
N
H
L
L
H
V
E
R
-
N
Q
P
Q
F
D
R
L
E
N
L
Y
L
D
H
N
--------
S
I
V
T
L
---
K
-
L
S
T
H
H
--
T
L
K
N
L
T
L
S
H
N
D
W
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
55.51
17%
-45
- C1 -
1XKU
3
PGS2_BOVIN
A:
[22-326]
-------------------------------------------------------------------------------------------------------------
G
P
V
C
P
--
F
R
C
Q
C
H
L
R
V
V
Q
C
S
D
L
G
L
E
K
V
P
---
K
D
L
P
P
D
T
A
L
L
D
---
L
Q
N
N
K
I
T
E
I
--------------------
K
DGD
F
K
N
---
L
---
K
N
L
H
T
---
L
I
L
I
N
N
K
-
I
S
K
I
-
S
PGA
F
A
P
L
V
K
L
E
R
L
Y
---
L
S
K
N
Q
L
K
E
L
-
P
---
E
K
M
P
K
T
L
Q
E
L
-
R
-
V
H
E
N
E
IT
K
V
R
K
S
V
F
N
G
L
------
N
Q
M
I
V
V
E
---
L
G
T
N
P
L
K
-
S
S
-
G
---
I
E
N
G
A
F
Q
GMKKL
S
Y
I
R
I
A
D
T
N
I
T
T
I
P
-
Q
G
L
P
P
-
S
L
T
E
L
H
L
D
G
N
K
I
T
K
V
D
AAS
L
K
G
L
N
N
L
A
K
L
G
-
L
S
F
N
S
I
S
A
V
---
D
N
G
S
L
A
N
T
P
H
L
R
-------
E
L
H
L
-
N
N
N
K
L
V
K
V
P
G
G
L
-----------
A
D
H
K
Y
I
Q
V
V
----
Y
L
H
N
N
--------------
N
I
S
A
I
G
S
N
D
F
C
P
P
G
--
Y
N
T
K
K
A
S
Y
S
G
V
S
L
F
S
N
--------
P
V
Q
Y
W
---
E
-
I
Q
P
S
T
FR
C
V
Y
V
R
A
A
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------