@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0006: (2015-11-27 )
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDGKSARTIEFTEEEAKVVKGLFLLTTKPVLYVANVDEDKVADPDDIDYVNQIRAFAETENAEVVVISARAEEEISELDDEDKLEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAASIIHSDFERGFIRAVTMSYDDLIQYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
Atome Classification :
(20 SA)
-.........10........20....-.-...30........40........50....------...----.60........70........80--.--.--.--..-..---.90........100.......110.......120.......130.......140.......150..----.....----160.......170......-.180.-......190.......200.......210.......220.......230...--....240-.........250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MALTAGIVGLPNV
G
K
S
T
L
F
N
A
I
T
KA-G-AEAANYP
F
A
TIDPNV
G
M
V
EV
P
D
E
R
L
Q
K
L
T
------
E
LI----TPKKTVP
T
T
F
E
F
T
D
I
A
G
I
VKGAS--K--G--E--GL-
G
N
---
K
F
L
A
N
I
R
E
V
D
A
I
V
H
V
V
R
AFD
D
E
N
V
M
R
E
QGREDAFVDPIADI
D
T
I
N
L
E
L
I
L
A
D
L
E
S
I
N
K
R
Y
A
R
V
E
K
M
----
A
R
T
Q
K
----
D
K
E
S
V
A
E
F
N
V
L
Q
K
I
K
P
V
L
E-DGKS
A
-
R
T
I
E
F
T
E
E
E
A
K
V
V
K
G
L
F
L
L
TTK
P
V
L
Y
V
A
NVDEDKVADPD
D
I
D
Y
V
N
Q
I
R
A
F
AE--TENA
E
---
V
V
V
I
SAR
A
E
E
E
I
S
ELD
D
E
D
K
L
E
F
L
E
A
IGL
T
E
S
G
V
D
K
L
T
R
A
A
Y
H
L
LGLGTYFTAGE
K
E
V
R
A
W
T
F
KRGIKA
P
Q
A
A
S
I
I
H
S
D
F
E
R
G
F
I
R
A
V
TM
S
Y
D
D
L
I
Q
YG
S
E
K
A
V
K
E
A
G
R
L
R
E
E
G
K
E
Y
IVQDG
D
I
M
E
F
R
FNV
72
HHSearch
93.74
53%
-78
- C11 -
2DBY
4
?
A:
[1-366]
--
M
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
-
N
-
A
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
L
E
D
E
R
L
Y
A
L
Q
------
R
T
F
AKGE
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
--
K
--
G
--
E
--
G
L
-
G
N
---
Q
F
L
A
H
I
R
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
D
R
------
E
R
L
P
L
L
E
A
A
E
G
L
Y
V
H
L
Q
-
E
G
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
R
G
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
A
E
---
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
G
L
Q
E
S
G
L
Q
R
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
V
R
A
W
T
V
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
74
HHSearch
93.26
56%
-86
- C11 -
1JAL
-
YCHF_HAEIN
A:
[3-363]
---
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
-
G
-------
P
F
C
T
I
E
P
N
T
G
V
V
P
M
P
D
P
R
L
D
A
L
A
------
E
I
V
----
K
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
--
K
--
G
--
E
--
G
L
-
G
N
---
K
F
L
A
N
I
R
E
T
D
A
I
G
H
V
V
R
C
F
E
N
-------------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
----
A
K
G
G
-----
D
K
E
A
K
F
E
L
S
V
M
E
K
I
L
P
V
L
E
-
N
A
G
M
I
-
R
S
V
G
L
D
K
E
E
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
T
M
Y
I
A
N
V
N
E
D
G
F
E
N
N
---
P
Y
L
D
R
V
R
E
I
A
A
--
K
E
G
A
V
---
V
V
P
V
C
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
G
I
E
E
P
G
L
N
R
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
V
R
A
W
T
V
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
1
PsiBlast_PDB
92.56
54%
-87
- C11 -
1JAL
-
YCHF_HAEIN
A:
[1-363]
-
M
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
-
G
-------
P
F
C
T
I
E
P
N
T
G
V
V
P
M
P
D
P
R
L
D
A
L
A
------
E
I
V
----
K
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
--
K
--
G
--
E
--
G
L
-
G
N
---
K
F
L
A
N
I
R
E
T
D
A
I
G
H
V
V
R
C
F
E
N
-------------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
----
A
K
G
-
G
----
D
K
E
A
K
F
E
L
S
V
M
E
K
I
L
P
V
L
E
-
N
A
G
M
I
-
R
S
V
G
L
D
K
E
E
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
T
M
Y
I
A
N
V
N
E
D
G
F
---
E
N
N
P
Y
L
D
R
V
R
E
I
A
A
--
K
E
G
A
V
---
V
V
P
V
C
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
G
I
E
E
P
G
L
N
R
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
V
R
A
W
T
V
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
3
PsiBlast_PDB
92.24
52%
-79
- C11 -
2DBY
4
?
A:
[2-366]
---
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
-
N
-
A
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
----
P
P
--
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
--
K
--
G
--
E
--
G
L
-
G
N
---
Q
F
L
A
H
I
R
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
------
D
R
E
R
L
P
L
L
E
A
A
E
G
L
Y
V
H
L
Q
-
E
G
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
R
G
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
A
E
---
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
G
L
Q
E
S
G
L
Q
R
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
V
R
A
W
T
V
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
2
PsiBlast_PDB
89.90
52%
-81
- C11 -
2DWQ
-
?
A:
[2-367]
---
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
-
N
-
A
L
A
A
-----
T
I
D
K
N
V
G
V
V
P
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
----
P
P
--
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
--
K
--
G
--
E
--
G
L
-
G
N
---
Q
F
L
A
H
I
R
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-------------
D
P
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
----
A
R
A
------
D
R
E
R
L
P
L
L
E
A
A
E
G
L
Y
V
H
L
Q
-
E
G
K
P
A
-
R
T
F
P
P
S
E
A
V
A
R
F
L
K
E
T
P
L
L
T
A
K
P
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
R
G
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
A
E
---
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
G
L
Q
E
S
G
L
Q
R
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
V
R
A
W
T
V
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
N
A
75
HHSearch
85.01
40%
-88
- C11 -
1NI3
1
OLA1_SCHPO
A:
[21-388]
---
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
L
-
G
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
----
K
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
--
T
--
G
--
V
--
G
L
-
G
N
---
A
F
L
S
H
V
R
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
----
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
----
T
S
R
G
A
NTLE
M
K
A
K
K
E
E
Q
A
I
I
E
K
V
Y
Q
Y
L
T
E
T
K
Q
P
I
-
R
K
G
D
W
S
N
R
E
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
Q
-
K
N
K
Y
L
P
K
I
K
K
W
I
D
E
N
S
P
G
D
T
---
L
I
P
M
S
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
N
T
K
-
S
M
L
P
K
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
V
R
S
W
T
I
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
4
PsiBlast_PDB
84.08
40%
-83
- C11 -
1NI3
1
OLA1_SCHPO
A:
[21-388]
---
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
-
V
L
G
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
----
K
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
--
T
--
G
--
V
--
G
L
-
G
N
---
A
F
L
S
H
V
R
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
----
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
TSRG
A
N
T
L
E
----
M
K
A
K
K
E
E
Q
A
I
I
E
K
V
Y
Q
Y
L
T
-
E
T
K
Q
P
I
R
K
G
D
W
S
N
R
E
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
Q
K
N
-
K
Y
L
P
K
I
K
K
W
I
D
---
E
N
S
P
G
D
T
L
I
P
M
S
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
N
-
T
K
S
M
L
P
K
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
V
R
S
W
T
I
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
92
HHSearch
46.87
23%
-70
- C9 -
2QTF
3
HFLX_SULSO
A:
[179-269]
--
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
-------------
M
S
P
K
R
Y
A
I
P
I
N
N
---------------------------
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
--
P
--
Q
--
I
V
-
D
A
-
F
F
---
V
T
L
S
E
A
K
Y
S
D
A
L
I
L
V
I
D
S
T
F
S
E
N
L
L
I
E
T
L
Q
S
S
F
E
I
L
R
E
I
G
V
S
G
K
P
I
L
V
T
L
N
K
I
D
K
I
N
G
D
L
Y
K
K
L
D
L
----
V
E
K
L
S
----
K
E
L
Y
S
P
I
F
D
V
I
P
I
S
A
L
K
R
T
-
N
L
E
L
L
-
R
D
K
I
Y
Q
L
A
T
Q
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90
HHSearch
46.51
36%
-108
- C9 -
1MKY
3
DER_THEMA
A:
[2-93]
---
A
T
V
L
I
V
G
R
P
N
V
G
K
S
T
L
F
N
K
L
V
K
---------------
D
P
V
Q
D
T
V
E
W
Y
G
---------------------------
K
T
F
K
L
V
D
T
C
G
V
F
D
N
P
Q
--
D
II
S
--
Q
--
K
M
-
K
E
---
V
T
L
N
M
I
R
E
A
D
L
V
L
F
V
V
D
G
K
R
G
I
T
K
E
D
E
S
L
A
D
F
L
R
K
S
T
V
D
T
I
L
V
A
N
K
A
E
N
L
R
E
F
E
R
E
V
K
P
E
L
Y
S
L
G
F
----
G
E
P
I
P
----
V
S
A
E
H
N
I
N
L
D
T
M
L
E
T
I
I
K
K
-
L
E
E
K
G
-
L
D
L
E
S
K
P
E
I
T
D
A
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
E
R
A
L
V
S
P
I
P
V
D
D
E
V
F
I
D
--
G
R
K
Y
V
---
F
V
D
T
A
G
L
E
K
Y
S
N
Y
R
V
V
D
S
I
E
K
A
D
V
V
V
I
V
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
G
L
M
E
R
R
G
R
A
S
V
V
V
F
N
K
W
D
L
V
V
H
R
E
K
R
Y
D
E
F
T
K
L
F
R
E
K
L
Y
F
I
D
Y
S
P
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
A
S
Y
T
T
K
V
P
S
S
A
I
N
S
A
L
Q
K
V
L
79
HHSearch
45.68
42%
-72
- C9 -
1LNZ
2
OBG_BACSU
A:
[158-248]
--
L
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
-
P
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
T
D
D
G
--------------------------
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
--
Q
--
G
--
V
--
G
L
-
G
H
---
Q
F
L
R
H
I
E
R
T
R
V
I
V
H
V
I
D
M
S
G
L
E
G
R
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
N
L
R
L
T
E
R
P
Q
I
I
V
A
N
K
M
D
M
P
E
A
A
E
N
L
E
----
A
F
K
E
K
----
L
T
D
D
Y
P
V
F
P
I
S
A
V
T
R
E
G
L
R
-
E
L
L
F
E
-
V
A
N
Q
L
E
N
T
P
E
F
P
L
Y
D
E
E
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
HHSearch
45.45
46%
-80
- C9 -
1UDX
3
OBG_THET8
A:
[157-247]
--
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
-
P
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
E
E
--------------------------
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
--
E
--
G
--
K
--
G
L
-
G
L
---
E
F
L
R
H
I
A
R
T
R
V
L
L
Y
V
L
D
A
A
D
E
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
L
L
E
E
E
A
V
K
A
L
A
D
A
----
L
A
R
E
G
----
L
A
V
L
P
V
S
A
L
T
G
A
G
L
P
A
L
K
E
-
A
L
H
A
L
-
V
R
S
T
P
P
P
E
M
P
K
P
V
P
Q
A
G
V
E
V
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
V
E
R
Y
L
A
R
I
K
G
D
L
M
E
A
A
G
Y
--
L
Q
E
V
F
---
R
R
Q
G
V
E
A
A
L
R
A
K
G
V
R
A
G
D
L
V
R
I
G
G
L
E
F
E
Y
I
P
E
V
--------------------------------------------------------------------------------------------------
96
HHSearch
42.62
30%
-42
- C9 -
2DYK
1
?
A:
[2-90]
---
H
K
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
-
R
-
S
----------
D
L
K
E
G
V
V
E
T
D
R
---------------------------
G
R
F
L
L
V
D
T
G
G
L
W
S
G
D
K
--
W
--
E
--
K
--
K
I
-
Q
E
---
K
V
D
R
A
L
E
D
A
E
V
V
L
F
A
V
D
G
R
A
E
L
T
Q
A
D
Y
E
V
A
E
Y
L
R
R
K
G
K
P
V
I
L
V
A
T
K
V
D
D
P
K
H
E
L
Y
L
G
P
L
Y
G
L
G
F
G
D
----
P
I
P
T
S
----
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
42.48
34%
-95
- C9 -
1MKY
2
DER_THEMA
A:
[180-275]
--
A
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
-
E
R
A
L
V
S
P
I
P
------
V
D
D
E
V
F
I
D
G
---------------------------
R
K
Y
V
F
V
D
T
A
G
L
--------------EK
Y
S
-
N
Y
---
R
V
V
D
S
I
E
K
A
D
V
V
V
I
V
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
G
L
M
E
R
R
G
R
A
S
V
V
V
F
N
K
W
D
L
V
V
H
R
E
K
R
Y
D
E
F
T
K
L
F
R
E
----
K
L
Y
F
I
----
D
Y
S
P
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
-
I
D
A
M
N
-
L
A
Y
A
S
Y
T
T
K
V
P
S
S
A
I
N
S
A
L
Q
K
V
L
A
F
T
N
L
P
R
G
L
K
I
F
F
G
V
Q
V
D
I
K
P
P
T
F
L
F
F
V
N
--
S
I
E
K
V
---
K
N
P
Q
K
I
F
L
R
K
L
I
R
D
Y
V
F
P
F
E
G
S
P
I
F
L
K
F
K
R
S
R
---------------------------------------------------------------------------------------------------
91
HHSearch
41.74
31%
-80
- C9 -
1XZP
2
MNME_THEMA
A:
[243-335]
--
G
L
R
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
-
D
R
A
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
I
R
G
---------------------------
I
L
F
R
I
V
D
T
A
G
V
R
S
E
T
N
--
D
--
L
V-
E
--
R
L
G
I
E
---
R
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
S
S
P
L
D
E
E
D
R
K
I
L
E
R
I
K
N
K
R
Y
L
V
V
I
N
K
V
D
V
V
E
K
I
N
E
E
E
I
K
N
K
L
G
T
D
R
H
M
----
V
K
I
S
A
----
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
Q
E
-
I
F
E
R
G
-
S
D
S
L
I
T
N
L
R
Q
K
Q
L
L
E
N
V
K
G
H
L
E
D
A
I
K
S
L
K
E
G
M
P
V
D
M
A
S
I
D
L
E
R
A
L
N
L
L
D
E
V
T
--
G
R
S
F
R
---
E
D
L
L
D
T
I
F
S
N
F
C
V
G
K
--------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
41.50
40%
-68
- C9 -
1UDX
3
OBG_THET8
A:
[161-248]
------
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
-
H
-
P
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
V
S
E
E
E
--------------------------
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
--
E
--
G
--
K
--
G
L
-
G
L
---
E
F
L
R
H
I
A
R
T
R
V
L
L
Y
V
L
D
A
A
D
E
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
D
P
A
L
L
R
R
P
S
L
V
A
L
N
K
V
D
L
L
E
E
E
A
V
K
A
L
A
D
A
----
L
A
R
E
G
----
L
A
V
L
P
V
S
A
L
T
G
A
G
L
P
A
L
K
E
-
A
L
H
A
L
-
V
R
S
T
P
P
P
E
M
P
K
P
V
P
Q
A
G
V
E
V
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
V
E
R
Y
L
A
R
I
K
G
D
L
M
E
A
A
G
Y
--
L
Q
E
V
F
---
R
R
Q
G
V
E
A
A
L
R
A
K
G
V
R
A
G
D
L
V
R
I
G
G
L
E
F
E
Y
I
P
E
V
--------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
40.92
37%
-55
- C9 -
1LNZ
2
OBG_BACSU
A:
[162-265]
------
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
-
K
-
P
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
T
D
D
G
R
--------------------------
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
--
Q
--
G
--
V
--
G
L
-
G
H
---
Q
F
L
R
H
I
E
R
T
R
V
I
V
H
V
I
----
D
M
S
G
L
--
E
G
R
-----
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
N
L
R
L
T
E
R
P
Q
I
I
V
A
N
K
----
M
D
M
P
E
----
A
A
E
N
L
E
A
F
K
E
K
L
T
D
D
Y
P
V
F
-
P
I
S
A
V
-
T
R
E
G
L
R
E
L
L
F
E
V
A
N
Q
L
E
N
T
P
E
F
P
L
Y
D
E
E
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
100
Fugue
40.68
17%
-23
- C6 -
3I8S
-
FEOB_ECOLI
B:
[1-261]
M
K
K
L
T
I
G
L
I
G
N
P
N
S
G
K
T
T
L
F
N
Q
L
T
G
S
-
R
-
Q
R
V
G
N
W
A
G
V
T
V
E
R
K
E
G
Q
F
S
T
T
D
H
Q
V
T
L
V
D
------------------
L
P
G
T
Y
S
L
T
T
I
S
---
S
Q
T
S
--
L
--
D
--
E
--
Q
I
-
A
C
---
H
Y
I
L
S
-
G
D
A
D
L
L
I
N
V
V
D
--------------------
A
S
N
L
E
R
-
N
L
Y
L
T
L
Q
L
L
E
L
G
I
P
C
I
V
A
L
N
M
L
----
D
I
A
E
K
----
Q
N
I
R
I
E
I
D
A
L
S
A
R
L
G
C
P
V
I
-
P
L
V
S
T
-
R
G
-----------------
R
G
I
E
A
L
K
L
A
I
D
R
Y
K
A
N
E
N
V
E
L
V
H
Y
-------------
A
Q
P
---
L
L
N
E
A
D
S
L
A
K
V
M
P
S
D
I
P
L
K
Q
R
R
W
L
-
G
L
Q
M
L
E
----------------------
G
D
I
Y
S
R
A
Y
A
G
E
A
S
Q
H
L
D
A
A
L
A
R
L
R
N
E
M
D
---------
D
P
A
L
H
I
A
D
A
R
Y
Q
C
I
A
A
I
C
D
V
V
S
N
------------------
86
HHSearch
40.19
26%
-71
* C9 *
3A1S
2
?
A:
[5-95]
--
M
V
K
V
A
L
A
G
C
P
N
V
G
K
T
S
L
F
N
A
L
T
G
T
-
K
-
Q
Y
V
A
N
W
P
G
V
T
V
E
K
K
E
G
V
F
T
Y
K
G
---------------------------
Y
T
I
N
L
I
D
L
P
G
T
Y
S
L
G
Y
SS
I
--
D
--
E
--
K
I
-
A
R
---
D
Y
L
-
L
K
G
D
A
D
L
V
I
L
V
A
D
S
V
N
P
E
Q
S
L
Y
L
L
L
E
I
L
E
M
E
K
K
V
I
L
A
M
T
A
I
D
E
A
K
K
T
G
M
K
I
D
R
Y
E
L
Q
K
H
L
G
I
----
P
V
V
F
T
----
S
S
V
T
G
E
G
L
E
E
L
K
E
K
I
V
E
Y
A
-
Q
K
N
T
I
-
L
H
R
M
I
L
D
Y
G
E
K
V
E
S
E
I
K
K
V
E
N
F
L
R
D
K
K
L
R
I
N
P
R
Y
F
A
L
K
Y
L
S
G
D
P
E
F
Y
S
E
G
V
K
--
L
G
L
P
E
---
L
S
E
E
E
R
I
G
Y
R
L
L
I
A
K
R
K
R
E
Y
V
E
N
V
V
K
E
A
F
A
-----------------------------------------------------------------------------------------------------
85
HHSearch
40.04
27%
-80
- C9 -
3I8S
-
FEOB_ECOLI
A:
[3-97]
--
K
L
T
I
G
L
I
G
N
P
N
S
G
K
T
T
L
F
N
Q
L
T
G
S
-
R
-
Q
R
V
G
N
W
A
G
V
T
V
E
R
K
E
G
Q
F
S
T
T
D
---------------------------
H
Q
V
T
L
V
D
L
P
G
T
Y
S
L
T
T
---------T-
S
L
-
D
E
Q
I
A
C
H
Y
I
L
S
G
D
A
D
L
L
I
N
V
V
D
A
S
N
L
E
R
N
L
Y
L
T
L
Q
L
L
E
L
G
I
P
C
I
V
A
L
N
M
L
D
I
A
E
K
Q
N
I
R
I
E
I
D
A
L
S
A
R
L
G
C
----
P
V
I
P
L
----
V
S
T
R
G
R
G
I
E
A
L
K
L
A
I
D
R
Y
K
-
A
N
E
N
V
-
E
L
V
H
Y
A
Q
P
L
L
N
E
A
D
S
L
A
K
V
M
P
S
D
I
P
L
K
Q
R
R
W
L
G
L
Q
M
L
E
G
D
I
Y
S
R
A
Y
A
G
E
A
S
Q
--
H
L
D
A
A
---
L
A
R
L
R
N
E
M
D
D
P
A
L
H
I
A
D
A
R
Y
Q
C
I
A
A
I
C
D
V
V
S
N
T
L
T
------------------------------------------------------------------------------------------------
89
HHSearch
39.47
28%
-62
- C9 -
2WJG
1
FEOB_METJA
A:
[7-96]
--
S
Y
E
I
A
L
I
G
N
P
N
V
G
K
S
T
I
F
N
A
L
T
G
E
-
N
-
V
Y
I
G
N
W
P
G
V
T
V
E
K
K
E
G
E
F
E
Y
N
G
---------------------------
E
K
F
K
V
V
D
L
P
G
V
Y
S
L
T
A
--
N
--
S
I
D
E
--
I
I
-
A
R
---
D
Y
-
I
I
N
E
K
P
D
L
V
V
N
I
V
D
A
T
A
L
E
R
N
L
Y
L
T
L
Q
L
M
E
M
G
A
N
L
L
L
A
L
N
K
M
D
L
A
K
S
L
G
I
E
I
D
V
D
K
L
E
K
I
L
G
V
----
K
V
V
P
L
----
S
A
A
K
K
M
G
I
E
E
L
K
K
A
I
S
I
A
V
-
K
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------