@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0061: (2015-11-28 )
MGIKVYKPTTNGRRNMTSLDFAEITTNTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYILAPKGLEVGQRIISGPEADIKVGNALPLANIPVGTVIHNIELQPGKGAELIRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRNRWKGVRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNQK
Atome Classification :
(20 SA)
-----------------------------------------------------------------.........10........20........30........40...----.....50........60........-----70..-....----..80.......---.90--....--.....100..--------..---------...110.-.-.-..-..120----.------.......130.......140..---------...---..150.......160.......170........180.-..----------....190.......200..----.....210-------------.-------.---......-220.......230.......240.......250.....-..260.......270.....------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------MG
I
K
V
Y
KPTTNGRRNMTSLD
F
A
E
ITTNTP
E
K
S
L
L
V
S
L
K
N
KAGRN----NN
G
R
I
T
V
R
HQGGGH
K
R
H
Y
R
L
I
D
F
KR-----NK
D
G
-
V
E
A
V
----
V
K
T
IEYDPNR
T
---
A
N
---
I
A
L
V
--
H
YTDG
V
K
A
Y
I
--------LA---------PK
G
L
E
V
G
-
Q
-
R
-
I
I-SGPE-----A------
D
I
KVGNALPLANIP
V
G
T
V
I
H
N
I
---------
E
LQ---PGKG
A
E
L
I
R
AAGASA
Q
V
LGQEG
K
Y
-
V
L
V
R
LQSG
E
V
R
M
-
I
L
----------
G
T
C
R
A
T
I
GTVG
N
E
Q
Q
S
L
V
N
----
I
G
KAGRN--------------R-------W---KGVRPT-VRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGL-KTRNKKAKSD
K
L
I
V
RRRNQK------------------------------
2
PsiBlast_PDB
91.26
75%
-47
- C3 -
3J3W
-
RL2_BACSU
C:
[1-277]
-----------------------------------------------------------------
M
A
I
K
K
Y
K
P
T
S
N
G
R
R
G
M
T
T
S
D
F
A
E
I
T
T
D
K
P
E
K
S
L
L
A
P
L
H
K
K
G
G
R
N
----
N
Q
G
K
L
T
V
R
H
Q
G
G
G
H
K
R
Q
Y
R
V
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
V
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
L
A
---------
P
K
G
I
Q
V
G
-
T
-
E
-
I
M
-
S
G
P
E
-----
A
------
D
I
K
V
G
N
A
L
P
L
I
N
I
P
V
G
T
V
V
H
N
I
---------
E
L
K
---
P
G
K
G
G
Q
L
V
R
S
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
L
V
R
L
N
S
G
E
V
R
M
-
I
L
----------
S
A
C
R
A
S
I
G
Q
V
G
N
E
Q
H
E
L
I
N
----
I
G
K
A
G
R
S
--------------
R
-------
W
---
K
G
I
R
P
T
-
V
R
G
S
V
M
N
P
N
D
H
P
H
G
G
G
E
G
R
A
P
I
G
R
K
S
P
M
S
P
W
G
K
P
T
L
G
F
-
K
T
R
K
K
K
N
K
S
D
K
F
I
V
R
R
R
K
N
K
------------------------------
14
PsiBlast_PDB
90.14
71%
-108
- C3 -
487D
-
RL2_ECOLI
I:
[1-135]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
-
M
-
E
-
I
M
-
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
----------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
89.36
59%
-52
- C3 -
4U67
-
?
A:
[13-272]
-----------------------------------------------------------------------------
R
R
Q
M
T
T
A
D
F
S
G
L
T
K
K
R
P
E
K
A
L
T
E
A
L
P
K
T
G
G
R
N
----
N
R
G
R
I
T
S
R
F
I
G
G
G
H
K
R
L
Y
R
I
I
D
F
K
R
R----
D
K
S
G
-
V
N
A
K
----
V
A
A
I
E
Y
D
P
N
R
S
---
A
R
---
I
A
L
L
--
H
Y
A
D
G
E
K
R
Y
I
--------
L
A
---------
P
E
G
L
T
V
G
-
A
-
T
-
V
N
-
A
G
P
E
-----
A
------
E
P
K
L
G
N
A
L
P
L
R
F
V
P
V
G
A
V
V
H
A
L
---------
E
L
V
---
P
G
K
G
A
Q
L
A
R
S
A
G
T
S
V
Q
V
Q
G
K
E
S
D
Y
-
V
I
V
R
L
P
S
G
E
L
R
R
-
V
H
----------
S
E
C
Y
A
T
I
G
A
V
G
N
A
E
H
K
N
I
V
----
L
G
K
A
G
R
S
--------------
R
-------
W
---
L
G
R
K
P
H
-
Q
R
G
S
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
T
G
A
G
R
-
V
P
V
T
P
W
G
K
P
T
K
G
L
-
K
T
R
R
K
R
K
T
S
D
R
F
I
V
T
-----------------------------------
5
PsiBlast_PDB
89.25
59%
-57
- C3 -
2ZJQ
-
RL2_DEIRA
A:
[33-272]
-------------------------------------------------------------------------------------------------
L
T
E
A
L
P
K
T
G
G
R
N
----
N
R
G
R
I
T
S
R
F
I
G
G
G
H
K
R
L
Y
R
I
I
D
F
K
R
R----
D
K
S
G
-
V
N
A
K
----
V
A
A
I
E
Y
D
P
N
R
S
---
A
R
---
I
A
L
L
--
H
Y
A
D
G
E
K
R
Y
I
--------
L
A
---------
P
E
G
L
T
V
G
-
A
-
T
-
V
N
-
A
G
P
E
-----
A
------
E
P
K
L
G
N
A
L
P
L
R
F
V
P
V
G
A
V
V
H
A
L
---------
E
L
V
---
P
G
K
G
A
Q
L
A
R
S
A
G
T
S
V
Q
V
Q
G
K
E
S
D
Y
-
V
I
V
R
L
P
S
G
E
L
R
R
-
V
H
----------
S
E
C
Y
A
T
I
G
A
V
G
N
A
E
H
K
N
I
V
----
L
G
K
A
G
R
S
--------------
R
-------
W
---
L
G
R
K
P
H
-
Q
R
G
S
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
T
G
A
G
R
-
V
P
V
T
P
W
G
K
P
T
K
G
L
-
K
T
R
R
K
R
K
T
S
D
R
F
I
V
T
-----------------------------------
15
PsiBlast_PDB
87.66
38%
-66
- C3 -
3J7Y
-
RM02_HUMAN
D:
[62-270]
------------------------------------------------------------------------------------
N
F
V
S
W
K
S
R
T
K
Y
T
I
T
P
V
K
M
R
K
S
G
G
R
D
----
H
T
G
R
I
R
V
H
G
I
G
G
G
H
K
Q
R
Y
R
M
I
D
F
L
R
FRPEE
T
K
S
G
P
F
E
E
K
----
V
I
Q
V
R
Y
D
P
C
R
S
---
A
D
---
I
A
L
V
---
A
G
G
S
R
K
R
W
I
--------
I
A
---------
T
E
N
M
Q
A
G
-
D
-
T
-
I
L
-
N
S
N
H
IGRMA
V
------
A
A
R
E
G
D
A
H
P
L
G
A
L
P
V
G
T
L
I
N
N
V
---------
E
S
E
---
P
G
R
G
A
Q
Y
I
R
A
A
G
T
C
G
V
L
L
R
K
V
N
G
T
-
A
I
I
Q
L
P
S
K
R
Q
M
Q
-
V
L
----------
E
T
C
V
A
T
V
G
R
V
S
N
V
D
H
N
K
R
V
----
I
G
K
A
G
R
N
--------------
R
-------
W
---
L
G
K
R
P
N
-
S
G
R
W
H
R
K
G
G
W
A
G
R
K
I
R
P
L
P
P
M
K
S
Y
V
----------------------------------------------------------------
11
PsiBlast_PDB
82.54
56%
-32
- C3 -
2J28
-
RL2_ECOLI
C:
[4-267]
-----------------------------------------------------------------------
K
P
T
S
P
G
R
R
H
V
V
K
V
V
N
P
E
L
H
K
G
K
P
F
A
P
L
L
E
K
N
S
K
S
G
G
R
N
----
N
N
G
R
I
T
T
R
H
I
G
G
G
H
K
Q
A
Y
R
I
V
D
F
K
R
-----
N
K
D
G
-
I
P
A
V
----
V
E
R
L
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
V
--
L
Y
K
D
G
E
R
R
Y
I
--------
L
A
---------
P
K
G
L
K
A
G
-
D
-
Q
-
I
Q
-
S
G
V
D
-----
A
------
A
I
K
P
G
N
T
L
P
M
R
N
I
P
V
G
S
T
V
H
N
V
---------
E
M
K
---
P
G
K
G
G
Q
L
A
R
S
A
G
T
Y
V
Q
I
V
A
R
D
G
A
Y
-
V
T
L
R
L
R
S
G
E
M
R
K
-
V
E
----------
A
D
C
R
A
T
L
G
E
V
G
N
A
E
H
M
L
R
V
----
L
G
K
A
G
A
A
--------------
R
-------
W
---
R
G
V
R
P
T
-
V
R
G
T
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
N
-
F
G
-
K
H
P
V
T
P
W
G
V
Q
T
K
G
K
-
K
T
R
S
N
K
-
R
T
D
K
F
I
V
R
R
----------------------------------
6
PsiBlast_PDB
81.59
55%
-36
- C3 -
5AKA
-
RL2_ECOLI
C:
[3-269]
--------------------------------------------------------------------
V
K
C
K
P
T
S
P
G
R
R
H
V
V
K
V
V
N
P
E
L
H
K
G
K
P
F
A
P
L
L
E
K
N
S
K
S
G
G
R
N
----
N
N
G
R
I
T
T
R
H
I
G
G
G
H
K
Q
A
Y
R
I
V
D
F
K
R
-----
N
K
D
G
-
I
P
A
V
----
V
E
R
L
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
V
--
L
Y
K
D
G
E
R
R
Y
I
--------
L
A
---------
P
K
G
L
K
A
G
-
D
-
Q
-
I
Q
-
S
G
V
D
-----
A
------
A
I
K
P
G
N
T
L
P
M
R
N
I
P
V
G
S
T
V
H
N
V
---------
E
M
K
---
P
G
K
G
G
Q
L
A
R
S
A
G
T
Y
V
Q
I
V
A
R
D
G
A
Y
-
V
T
L
R
L
R
S
G
E
M
R
K
-
V
E
----------
A
D
C
R
A
T
L
G
E
V
G
N
A
E
H
M
L
R
V
----
L
G
K
A
G
A
A
--------------
R
-------
W
---
R
G
V
R
P
T
-
V
R
G
T
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
N
-
F
G
-
K
H
P
V
T
P
W
G
V
Q
T
K
G
K
-
K
T
R
S
N
K
-
R
T
D
K
F
I
V
R
R
----------------------------------
57
Fugue
75.39
68%
-98
- C3 -
1RL2
-
RL2_GEOSE
A:
[60-125]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
-G
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
--
M
E
-
I
-
M
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
G
---------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
74.90
73%
-80
- C3 -
1RL2
-
RL2_GEOSE
A:
[60-195]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
DKD-----
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
----
M
E
I
M
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
-
R
M
I
L
----------
G
K
C
R
A
T
V
G
E
V
G
---------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
74.71
68%
-95
- C3 -
1RL2
-
RL2_GEOSE
A:
[60-125]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
M
E
----
I
M
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
G
---------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
73.37
72%
-52
- C3 -
1C04
-
RL2_HALMA
A:
[60-194]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
-
M
-
E
-
I
M
-
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
----------------------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
73.07
73%
-57
* C3 *
1RL2
-
RL2_GEOSE
A:
[60-195]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
-
M
-
E
-
I
M
-
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
G
---------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
73.05
72%
-57
- C3 -
1RL2
-
RL2_GEOSE
A:
[60-195]
---------------------------------------------------------------------------------------------------------------------------------
Q
Y
R
I
I
D
F
K
R
-----
D
K
D
G
-
I
P
G
R
----
V
A
T
I
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
I
--
N
Y
A
D
G
E
K
R
Y
I
--------
I
A
---------
P
K
N
L
K
V
G
-
M
-
E
-
I
M
-
S
G
P
D
-----
A
------
D
I
K
I
G
N
A
L
P
L
E
N
I
P
V
G
T
L
V
H
N
I
---------
E
L
K
---
P
G
R
G
G
Q
L
V
R
A
A
G
T
S
A
Q
V
L
G
K
E
G
K
Y
-
V
I
V
R
L
A
S
G
E
V
R
M
-
I
L
----------
G
K
C
R
A
T
V
G
E
V
G
---------------------------------------------------------------------------------------------------------------------------------------------
59
Fugue
70.17
20%
-18
- C2 -
4RNZ
9
?
A:
[1-369]
M
E
R
L
V
W
D
KLT
L
L
G
F
L
E
K
N
HIPQ
K
L
Y
Y
N
LS
S
Q
D
K
E
L
S
A
E
IQSN
V
T
Y
Y
T
L
R
D
ANNTLI
Q
A
L
I
P
ISQD
L
Q
I
H
I
Y
K
K
-----
G
E
D
Y
F
L
D
F
I
P
I
I
F
T
R
K
E
K
T
L
L
L
S
L
Q
T
S
P
Y
Q
D
I
I
K
A
T
N
D
P
L
L
A
N
Q
L
M
N
A
Y
K
K
S
V
P
F
K
R
L
V
K
-----
N
D
---
K
I
A
I
----
V
Y
T
R
D
Y
R
V
G
Q
A
F
G
Q
P
T
---
I
K
M
A
--
M
V
S
S
R
S
N
Q
Y
Y
--------
L
F
S
H
SNG
H
Y
Y
D
S
K
A
Q
E
V
A
-
G
-
F
-
L
L
-
E
T
P
V
-----
K
------
Y
T
R
I
S
S
--
P
F
S
Y
G
R
F
H
R
P
H
Y
G
V
---------
D
Y
A
---
A
K
H
G
S
L
I
H
S
A
S
D
G
R
V
G
F
M
G
V
K
A
G
Y
G
K
V
V
E
I
H
L
N
E
L
R
L
-
V
Y
----------
A
H
M
S
A
F
A
N
--
G
L
K
K
G
S
F
V
K
KGQI
I
G
R
V
G
S
T
--------------
G
P
H
L
H
F
G
V
Y
---
K
N
S
R
P
I
N
P
L
G
Y
I
R
T
A
K
S
K
L
H
G
---
K
Q
R
E
V
F
L
E
K
A
Q
R
S
K
Q
K
L
E
E
L
L
-
K
T
H
S
F
E
K
N
S
F
Y
L
L
E
G
F
L
E
H
H
HH----------------------------
58
Fugue
69.27
18%
-13
- C2 -
4FHL
10
YEKI_SCHPO
A:
[2-392]
------------------------------------------------------------------
G
S
M
T
L
S
S
N
Q
Y
Q
L
P
L
N
V
R
P
Y
T
T
T
W
C
S
Q
S
P
S
C
S
N
L
L
A
I
G
H
D
T
G
--------
I
T
I
Y
C
A
S
E
E
S
T
G
L
T
L
Q
E
L
F
T
I
Q
T
-----
G
L
P
T
-
L
H
L
S
F
S
SS
C
S
Y
S
E
N
S
P
V
Y
S
---
L
F
---
L
A
C
V
--
C
Q
D
N
T
V
R
-
L
I
--------
I
T
---------
K
N
E
T
I
I
T
-
Q
-
H
-
V
L
-
G
G
K
S
-----
G
HHNFVN
D
I
D
I
A
D
V
Y
S
A
D
N
R
L
A
E
Q
V
I
A
S
V
GDDC
T
L
I
I
W
R
L
T
DE
G
P
I
L
A
G
Y
P
L
S
S
P
G
I
S
V
Q
F
R
P
S
N
P
N
Q
-
L
I
V
G
E
R
N
G
N
I
R
I
-
F
D
WTLNLTELVK
N
P
W
L
L
T
L
N
T
L
P
L
V
N
S
S
L
A
N
----
V
R
W
I
G
S
D
GS
G
I
L
A
M
C
KSG
A
W
L
R
-------
W
N
LF
K
N
L
L
P
N
-
V
Q
G
I
S
L
F
P
S
L
L
------
G
A
C
P
H
P
R
Y
M
D
Y
F
A
T
A
H
S
Q
H
G
L
I
Q
L
I
N
T
Y
E
K
D
S
N
S
I
P
I
Q
L
G
M
P
IV
D
F
C
W
H
QDGS
H
L
A
I
A
T
EG
S
V
L
L
T
R
L
MGFT
3
PsiBlast_PDB
68.92
59%
108
- C- -
1NKW
-
RL2_DEIRA
A:
[4-273]
--------------------------------------------------------------------
K
K
Y
R
P
Y
T
P
S
R
R
Q
M
T
T
A
D
F
S
G
L
T
K
K
R
P
E
K
A
L
T
E
A
L
P
K
T
G
G
R
N
----
N
R
G
R
I
T
S
R
F
I
G
G
G
H
K
R
L
Y
R
I
I
D
F
K
R
R----
D
K
S
G
-
V
N
A
K
----
V
A
A
I
E
Y
D
P
N
R
S
---
A
R
---
I
A
L
L
--
H
Y
A
D
G
E
K
R
Y
I
--------
L
A
---------
P
E
G
L
T
V
G
-
A
-
T
-
V
N
-
A
G
P
E
-----
A
------
E
P
K
L
G
N
A
L
P
L
R
F
V
P
V
G
A
V
V
H
A
L
---------
E
L
V
---
P
G
K
G
A
Q
L
A
R
S
A
G
T
S
V
Q
V
Q
G
K
E
S
D
Y
-
V
I
V
R
L
P
S
G
E
L
R
R
-
V
H
----------
S
E
C
Y
A
T
I
G
A
V
G
N
A
E
H
K
N
I
V
----
L
G
K
A
G
R
S
--------------
R
-------
W
---
L
G
R
K
P
H
-
Q
R
G
S
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
T
G
A
G
R
-
V
P
V
T
P
W
G
K
P
T
K
G
L
-
K
T
R
R
K
R
K
T
S
D
R
F
I
V
T
R
----------------------------------
7
PsiBlast_PDB
68.38
56%
108
- C- -
2RDO
-
RL2_ECOLI
C:
[6-269]
-----------------------------------------------------------------------
K
P
T
S
P
G
R
R
H
V
V
K
V
V
N
P
E
L
H
K
G
K
P
F
A
P
L
L
E
K
N
S
K
S
G
G
R
N
----
N
N
G
R
I
T
T
R
H
I
G
G
G
H
K
Q
A
Y
R
I
V
D
F
K
R
-----
N
K
D
G
-
I
P
A
V
----
V
E
R
L
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
V
--
L
Y
K
D
G
E
R
R
Y
I
--------
L
A
---------
P
K
G
L
K
A
G
-
D
-
Q
-
I
Q
-
S
G
V
D
-----
A
------
A
I
K
P
G
N
T
L
P
M
R
N
I
P
V
G
S
T
V
H
N
V
---------
E
M
K
---
P
G
K
G
G
Q
L
A
R
S
A
G
T
Y
V
Q
I
V
A
R
D
G
A
Y
-
V
T
L
R
L
R
S
G
E
M
R
K
-
V
E
----------
A
D
C
R
A
T
L
G
E
V
G
N
A
E
H
M
L
R
V
----
L
G
K
A
G
A
A
--------------
R
-------
W
---
R
G
V
R
P
T
-
V
R
G
T
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
N
-
F
G
-
K
H
P
V
T
P
W
G
V
Q
T
K
G
K
-
K
T
R
S
N
K
-
R
T
D
K
F
I
V
R
R
----------------------------------
9
PsiBlast_PDB
66.37
56%
28
- C3 -
3J5L
-
RL2_ECOLI
C:
[6-271]
-----------------------------------------------------------------------
K
P
T
S
P
G
R
R
H
V
V
K
V
V
N
P
E
L
H
K
G
K
P
F
A
P
L
L
E
K
N
S
K
S
G
G
R
N
----
N
N
G
R
I
T
T
R
H
I
G
G
G
H
K
Q
A
Y
R
I
V
D
F
K
R
-----
N
K
D
G
-
I
P
A
V
----
V
E
R
L
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
V
--
L
Y
K
D
G
E
R
R
Y
I
--------
L
A
---------
P
K
G
L
K
A
G
-
D
-
Q
-
I
Q
-
S
G
V
D
-----
A
------
A
I
K
P
G
N
T
L
P
M
R
N
I
P
V
G
S
T
V
H
N
V
---------
E
M
K
---
P
G
K
G
G
Q
L
A
R
S
A
G
T
Y
V
Q
I
V
A
R
D
G
A
Y
-
V
T
L
R
L
R
S
G
E
M
R
K
-
V
E
----------
A
D
C
R
A
T
L
G
E
V
G
N
A
E
H
M
L
R
V
----
L
G
K
A
G
A
A
--------------
R
-------
W
---
R
G
V
R
P
T
-
V
R
G
T
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
N
-
F
G
-
K
H
P
V
T
P
W
G
V
Q
T
K
G
K
-
K
T
R
S
N
K
-
R
T
D
K
F
I
V
R
R
R
S
--------------------------------
10
PsiBlast_PDB
65.99
56%
28
- C3 -
4UY8
-
RL2_ECOLI
C:
[6-271]
-----------------------------------------------------------------------
K
P
T
S
P
G
R
R
H
V
V
K
V
V
N
P
E
L
H
K
G
K
P
F
A
P
L
L
E
K
N
S
K
S
G
G
R
N
----
N
N
G
R
I
T
T
R
H
I
G
G
G
H
K
Q
A
Y
R
I
V
D
F
K
R
-----
N
K
D
G
-
I
P
A
V
----
V
E
R
L
E
Y
D
P
N
R
S
---
A
N
---
I
A
L
V
--
L
Y
K
D
G
E
R
R
Y
I
--------
L
A
---------
P
K
G
L
K
A
G
-
D
-
Q
-
I
Q
-
S
G
V
D
-----
A
------
A
I
K
P
G
N
T
L
P
M
R
N
I
P
V
G
S
T
V
H
N
V
---------
E
M
K
---
P
G
K
G
G
Q
L
A
R
S
A
G
T
Y
V
Q
I
V
A
R
D
G
A
Y
-
V
T
L
R
L
R
S
G
E
M
R
K
-
V
E
----------
A
D
C
R
A
T
L
G
E
V
G
N
A
E
H
M
L
R
V
----
L
G
K
A
G
A
A
--------------
R
-------
W
---
R
G
V
R
P
T
-
V
R
G
T
A
M
N
P
V
D
H
P
H
G
G
G
E
G
R
N
-
F
G
-
K
H
P
V
T
P
W
G
V
Q
T
K
G
K
-
K
T
R
S
N
K
-
R
T
D
K
F
I
V
R
R
R
S
--------------------------------
66
HHSearch
64.45
21%
-72
- C3 -
2CQA
-
A:
[7-72]
---------------------------------------------------------------------------------------------------------------------------------------
G
K
E
-----
E
T
E
I
-
I
E
G
E
----
V
V
E
I
Q
I
D
R
P
A
T
---
G
T
GS
K
V
G
K
L
T
L
K
T
T
E
M
E
T
I
Y
D
L
G
T
K
M
I
E
S
L
T
---------
K
D
K
V
Q
A
G
-
D
-
V
-
I
T
-
I
D
K
A
-----
T
------
G
K
I
S
K
L
G
R
S
F
T
R
A
R
S
G
P
S
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------