@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0191: (2015-11-29 )
MVDNKTVVIMLVFLARKNLSLYELTVQTKFSIKVIIEQINYLNSFLAKNHLPAIAHSAGRYQLLGDEKEHDKIVSLLEAEQFYLTQEERVCLIYLYSFCRREFVSNVHYQDFLKVSKNTTLSDIKMLRSKLAKRGISLTYTRAKGYSLVGDEMDKHQVAFQMITQLLESPIGFWSLNYILSSWKFALSYEKLEKTVEYFYESFQLSPIQDRLEKSLYFIILILCRYQRSVDRVLQGSPIVSEQLKELTTIIVTNLSQDISLSKPLDQKEKDYITLILSGCFEGEGTKDDDFFEALAKAIVDEMETVSLLNFSNKEELLQGLKRHIIPAYFRLKYGLTGDSGYTQNIKEHYSDLFLLVKKALRPLEEQVGLIPDSEISYFVIHFGGYLRQSGDTQSMSYKALILCPNGVSSSLVIKEKLRGLFPQIHFHRVSKIEQLKLIDNQTYDMVFSTIFVETKKPNYLVSLMMTAEQVQQLKELVISDFPKACLDDFQLDQLIATIKKYAHVHCEEELKLALRTMVKQDIFRKDVRPLLHQLITEETYQTSSEQMNWKEAIRLAAKPLLASGKITESYPEAMIEKVEEFGPFINLGKGIAIPHARPEDGVNSVGMSMLVLEQPIYLLDDPKQEIYLLLCIAAIDNETHLKALSHLTTILRDNNNVKALLASRGYQDIEMIIKQED
Atome Classification :
(20 SA)
.........10........20........--30........40........50........60........70.......---.80........90........100.......110.......120.......130.......140....-...150...---....160.......170.......180.......190.......200.......210.......220.......230.......240.......250.....--------------..260....-...270.......280.......290...--....300...--....310.......320.......330.......340.......350.......360.......370.......380.--......390.....--------..400.-......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.....-----------..540........550.......560...-..-..-----570.......580......-.---590......-.600..-.......610...--....-620--....----.....630.....--.--.640-.-......650.......660.......670......-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVDN
K
T
V
V
I
M
L
V
F
L
ARKN
L
S
L
Y
E
L
T
V
Q
T
K
--
F
S
I
K
V
I
I
E
Q
I
N
Y
L
N
S
F
L
A
KNH
L
P
A
I
AHSAG
R
Y
Q
LLGDE
K
E
H
D
K
I
V
S
L
L
E
---
A
E
Q
F
Y
LTQEER
V
C
L
I
Y
L
Y
S
F
C
R
R
E
F
V
S
NV
H
Y
Q
D
F
L
K
VSKNT
T
L
S
D
I
K
M
L
R
S
K
L
A
KRG
I
S
L
T
Y
T
RAKGY-SLVGDE
M
D
K
---
H
Q
V
A
F
Q
M
I
T
Q
L
L
ESPI
G
F
W
S
L
N
Y
I
L
S
S
W
K
F
A
L
S
Y
E
K
L
E
K
T
V
E
Y
F
Y
E
SFQLS
P
I
Q
D
R
L
E
K
S
L
Y
F
I
I
L
I
L
C
R
Y
Q
R
S
V
D
R
V
LQGSP
I
V
S
E
Q
L
K
E
L
T
T
I
I
V
TNLSQ--------------DISLSKPLD-QKEK
D
Y
I
T
L
I
L
S
G
CFEGEGTK
D
D
D
F
F
E
A
L
--
A
K
A
I
V
D
E
M
E
T
--
V
S
LLNFS
N
K
E
E
L
L
Q
G
L
K
R
H
I
I
P
A
Y
F
R
L
K
YGLTGDSGY
T
Q
N
I
K
E
H
Y
S
D
L
F
L
L
V
K
K
A
L
R
P
L
E
E
Q
VGLIPDSEI
S
Y
F
V
I
HF--GGYLRQSGDTQS
M
S
--------
Y
K
A
L
I
L-CPNGVS
S
S
L
V
I
K
E
K
L
R
G
LF
P
Q
I
H
F
H
R
V
S
K
I
E
Q
L
KLIDNQ
T
Y
D
M
V
F
S
T
I
F
V
ETKKPN
Y
L
V
S
L
M
M
T
A
E
Q
V
Q
Q
L
K
E
L
V
I
SDF
P
K
A
C
L
D
D
F
Q
L
D
Q
L
I
A
T
I
K
K
Y
A
H
V
H
C
E
E
E
L
K
L
A
L
R
T
M
V
K
Q
D
I
F
R
K
D
V
R
P
L
L
H
Q
L
I
T
-----------
E
E
T-YQTSSEQM
N
W
K
E
A
I
R
L
A
A
K
P
LLASG-KI-TE-----S
Y
P
E
A
M
I
E
K
V
E
E
FGPFINL-G---KGIAIPHAR-PE--DG-
V
N
S
VG
M
S
M
L
V
LEQ--
P
I
Y
L-L----DDPK----
Q
E
I
Y
L
L
L
C
I
AAID--N--
E
T
H
L
-
K
-
A
L
S
H
L
T
T
I
L
RDNN
N
V
K
A
L
L
A
SRG
Y
Q
D
I
E
M
I
IKQED-
50
Fugue
75.65
16%
-30
- C1 -
4RKN
14
MCCA_WOLSU
A:
[43-702]
--------
M
Q
M
T
K
E
A
R
E
I
I
A
H
P
K
G
T
K
E
S
R
GV
I
S
L
Q
D
Y
I
V
E
E
Q
A
M
Y
D
W
L
F
K
N
H
-
P
I
F
T
K
Y
G
G
K
T
V
--
G
K
L
V
V
K
D
R
G
E
E
W
I
E
EGR
G
N
D
F
S
K
A
S
K
R
S
G
G
E
G
F
S
S
M
M
Y
R
V
A
R
N
S
T
L
Q
Y
P
N
--
K
F
I
G
P
E
K
C
G
E
C
H
P
A
Q
Y
E
T
W
S
R
S
R
H
A
T
T
I
R
F
P
G
E
H
P
E
V
N
N
K
L
N
D
PVF
D
K
D
T
A
S
I
L
P
Q
G
I
T
P
D
V
V
Y
C
T
V
G
H
I
R
T
K
F
G
F
F
D
A
W
--------
L
L
R
G
T
Y
H
V
E
G
--
G
L
L
K
N
G
T
G
Q
I
V
A
G
G
N
Q
W
Q
R
T
W
A
L
N
L
--
S
P
E
V
A
K
K
I
K
K
W
V
P
D
F
P
V
T
L
E
E
YGDNGGYVRG
L
A
S
Y
A
A
K
Y
K
K
S
M
S
F
Q
A
S
T
S
Y
C
E
V
C
H
P
--
W
K
F
D
F
K
N
E
S
E
F
Y
A
A
L
GN
A
K
E
L
Q
K
H
T
I
S
KG
V
S
C
E
E
C
H
G
A
G
G
H
L
E
G
G
S
G
L
L
I
S
N
C
E
R
C
H
Q
R
F
S
Y
S
P
D
L
M
R
N
N
P
L
N
A
G
K
P
D
L
A
L
S
S
K
F
K
S
M
G
P
G
C
G
S
--
E
G
S
Q
T
Y
F
T
A
H
Y
E
K
G
M
R
C
A
T
C
H
D
P
H
D
V
T
GN
V
T
G
E
KG
I
K
G
V
S
Y
N
S
E
Q
G
Y
L
S
S
L
Y
S
K
P
K
L
K
K
E
C
T
D
C
H
-------------
K
E
Q
A
Y
I
Q
S
K
A
D
T
H
S
K
N
S
C
A
S
C
H
M
P
F
M
M
S
C
E
N
F
Y
A
I
Q
F
-----
Q
D
Q
A
G
F
D
T
Q
R
R
----------
A
H
------------------
I
W
K
I
D
V
D
P
A
R
K
S
L
V
A
G
STSKDPRDGK
D
W
H
-
F
E
R
N
E
E
G
R
N
F
V
D
L
M
W
A
C
A
R
T
T
W
A
D
K
-
D
Q
-
A
E
A
KGCH
S
P
V
V
S
E
L
K
E
T
L
H
F
K
D
Q
K
Q
V
-
Y
---
N
E
V
M
G
W
Q
T
P
-
V
K
--
D
K
-
F
T
Q
V
K
V
G
I
Q
G
L
Y
S
L
L
E
V
K
K
-
L
----
A
P
S
D
----
K
T
R
V
Y
E
L
I
E
K
A
Q
D
--
T
--
V
D
L
I
-
E
-
K
D
G
S
W
G
M
H
G
F
K
Y
T
K
Q
R
L
D
A
A
V
E
Y
I
N
E
A
Q
R
I
M
K
K
S
L
-
19
PsiBlast_CBE
72.64
33%
-77
- C4 -
3OXP
2
?
B:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
T
L
L
T
-----------
S
D
V
-
I
Q
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
I
D
N
G
-
A
V
-
E
A
-----
R
Y
V
E
A
I
Y
R
S
H
E
A
I
G
P
Y
Y
V
V
-
G
---
P
G
I
A
M
P
H
A
R
-
P
E
--
D
G
-
V
N
R
L
S
L
A
L
T
V
I
T
E
--
G
V
T
F
-
N
----
A
E
G
N
----
D
P
V
K
L
L
I
V
L
A
A
T
D
--
S
--
N
S
H
I
-
E
-
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
I
L
S
V
I
A
R
Y
--
21
HHSearch
72.04
33%
-75
- C4 -
3OXP
1
?
A:
[4-150]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
K
T
L
L
T
-----------
S
D
V
-
I
Q
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
I
D
N
G
-
A
V
-
E
A
-----
R
Y
V
E
A
I
Y
R
S
H
E
A
I
G
P
Y
Y
V
V
-
G
---
P
G
I
A
M
P
H
A
R
-
P
E
--
D
G
-
V
N
R
L
S
L
A
L
T
V
I
T
E
--
G
V
T
F
-
N
----
A
E
G
N
----
D
P
V
K
L
L
I
V
L
A
A
T
D
--
S
--
N
S
H
I
-
E
-
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
I
L
S
V
I
A
R
Y
--
1
PsiBlast_PDB
71.96
33%
-77
- C4 -
3OXP
1
?
A:
[5-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
T
L
L
T
-----------
S
D
V
-
I
Q
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
I
D
N
G
-
A
V
-
E
A
-----
R
Y
V
E
A
I
Y
R
S
H
E
A
I
G
P
Y
Y
V
V
-
G
---
P
G
I
A
M
P
H
A
R
-
P
E
--
D
G
-
V
N
R
L
S
L
A
L
T
V
I
T
E
--
G
V
T
F
-
N
----
A
E
G
N
----
D
P
V
K
L
L
I
V
L
A
A
T
D
--
S
--
N
S
H
I
-
E
-
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
I
L
S
V
I
A
R
Y
--
23
HHSearch
70.00
30%
-83
- C4 -
2OQ3
-
PTMA_ECOLI
A:
[2-147]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
S
D
Y
F
P
-----------
E
S
S
-
I
S
V
I
H
S
A
K
D
W
Q
E
A
I
D
F
S
M
V
S
L
L
D
K
N
-
Y
I
-
S
E
-----
N
Y
I
Q
A
I
K
D
S
T
I
N
N
G
P
Y
Y
I
L
-
A
---
P
G
V
A
M
P
H
A
R
-
P
E
---
C
G
A
L
K
T
G
M
S
L
T
L
L
E
Q
--
G
V
Y
F
-
P
----
G
N
D
-----
E
P
I
K
L
L
I
G
L
S
A
A
D
--
A
--
D
S
H
I
-
G
-
A
I
Q
A
L
S
E
L
L
C
E
E
E
I
L
E
Q
L
L
T
A
S
S
E
K
Q
L
A
D
I
I
S
R
G
--
25
HHSearch
68.82
29%
-84
- C4 -
3BJV
-
?
A:
[3-148]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
Q
A
F
K
-----------
E
N
H
S
I
R
L
G
L
T
A
K
D
W
K
E
A
V
K
L
S
V
T
P
L
I
E
S
G
-
A
V
-
K
P
-----
E
Y
Y
N
A
I
I
E
S
T
E
S
Y
G
P
Y
Y
I
L
-
M
---
P
G
M
A
M
P
H
A
R
-
P
E
--
A
G
-
V
Q
R
D
A
F
S
L
V
T
L
T
E
--
P
V
T
F
-
T
----
D
G
------
K
E
V
Q
V
L
L
A
L
A
A
T
S
--
S
--
K
I
H
T
S
V
-
A
I
P
Q
I
I
A
L
F
E
L
D
H
S
I
E
R
L
V
N
C
K
T
P
E
E
V
L
A
M
V
E
E
S
K
-
2
PsiBlast_PDB
68.63
30%
-97
- C4 -
3BJV
-
?
A:
[21-147]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
W
K
E
A
V
K
L
S
V
T
P
L
I
E
S
G
-
A
V
-
K
P
-----
E
Y
Y
N
A
I
I
E
S
T
E
S
Y
G
P
Y
Y
I
L
-
M
---
P
G
M
A
M
P
H
A
R
-
P
E
--
A
G
-
V
Q
R
D
A
F
S
L
V
T
L
T
E
--
P
V
T
F
-
T
----
D
G
------
K
E
V
Q
V
L
L
A
L
A
A
T
S
--
S
--
K
I
H
T
-
S
V
A
I
P
Q
I
I
A
L
F
E
L
D
H
S
I
E
R
L
V
N
C
K
T
P
E
E
V
L
A
M
V
E
E
S
K
-
27
HHSearch
67.51
20%
-75
- C4 -
2A0J
-
?
A:
[4-147]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
E
I
L
P
-----------
L
S
H
-
I
V
L
D
M
E
V
G
S
K
K
R
L
F
E
E
A
G
L
L
L
E
R
E
S
-
S
L
S
H
A
-----
D
V
F
E
C
L
F
A
R
-
E
K
L
G
S
T
-
G
L
-
G
---
Q
G
V
A
I
P
H
G
R
-
H
A
---
G
-
V
K
Q
A
T
G
A
F
I
R
T
R
E
--
P
V
G
F
-
D
----
A
P
D
G
----
K
P
V
S
L
I
F
I
L
L
V
P
E
--
N
A
T
G
E
H
L
-
E
-
V
L
S
K
L
A
G
K
F
S
Q
K
S
I
R
E
S
L
M
T
V
S
S
A
E
E
V
R
A
I
L
T
----
24
HHSearch
65.63
24%
-64
- C4 -
1A3A
-
PTM3C_ECOLI
A:
[4-147]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
K
L
G
-----------
A
E
N
-
I
F
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
-
Y
V
-
E
P
-----
E
Y
V
Q
A
M
L
D
R
-
E
K
L
T
P
-
T
Y
L
-
G
---
E
S
I
A
V
P
H
G
T
-
V
E
AK
D
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
--
G
V
R
F
-
G
----
E
E
E
D
----
D
I
A
R
L
V
I
G
I
A
A
R
N
--
N
---
E
H
I
-
Q
-
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
K
-
43
Fugue
64.55
23%
-69
- C4 -
1A6J
1
PTSN_ECOLI
A:
[8-157]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
L
S
S
V
L
N
-----------
R
E
C
-
T
R
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
A
K
Q
L
-
S
L
-
P
P
-----
Q
V
V
F
E
A
I
L
T
R
E
K
M
G
S
T
-
G
I
-
G
---
N
G
I
A
I
P
H
G
K
L
-
E
--
E
D
-
T
L
R
A
V
G
V
F
V
Q
L
E
T
--
P
I
A
F
D
A
----
I
D
-
N
----
Q
P
V
D
L
L
F
A
L
L
V
P
A
--
D
QT
K
T
H
L
-
H
-
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
L
Y
Q
I
I
T
D
T
E
-
6
PsiBlast_PDB
64.33
30%
-69
- C4 -
1J6T
-
A:
[22-131]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
-
Y
V
-
E
P
-----
E
Y
V
Q
A
M
L
D
R
-
E
K
L
T
P
-
T
Y
L
-
G
---
E
S
I
A
V
P
H
G
T
-
V
E
AK
D
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
--
G
V
R
F
-
G
----
E
E
E
D
----
D
I
A
R
L
V
I
G
I
A
A
R
N
--
N
--
E
-
H
I
-
Q
-
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
--
28
HHSearch
63.45
23%
-68
- C4 -
1A6J
1
PTSN_ECOLI
A:
[8-155]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
L
S
S
V
L
N
-----------
R
E
C
-
T
R
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
A
K
Q
L
-
S
L
P
P
Q
-----
V
V
F
E
A
I
L
T
R
-
E
K
M
G
S
T
-
G
I
-
G
---
N
G
I
A
I
P
H
G
K
-
L
E
--
E
D
-
T
L
R
A
V
G
V
F
V
Q
L
E
T
--
P
I
A
F
-
D
----
A
I
D
N
----
Q
P
V
D
L
L
F
A
L
L
V
P
A
DQ
T
--
K
T
H
L
-
H
-
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
L
Y
Q
I
I
T
D
T
E
-
7
PsiBlast_PDB
62.48
29%
-67
- C4 -
2FEW
-
A:
[22-131]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
-
Y
V
-
E
P
-----
E
Y
V
Q
A
M
L
D
R
-
E
K
L
T
P
-
T
Y
L
-
G
---
E
S
I
A
V
P
Q
G
T
-
V
E
AK
D
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
--
G
V
R
F
-
G
----
E
E
E
D
----
D
I
A
R
L
V
I
G
I
A
A
R
N
--
N
--
E
-
H
I
-
Q
-
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
--
5
PsiBlast_PDB
62.11
30%
-68
- C4 -
1A3A
-
PTM3C_ECOLI
A:
[22-131]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
-
Y
V
-
E
P
-----
E
Y
V
Q
A
M
L
D
R
-
E
K
L
T
P
-
T
Y
L
-
G
---
E
S
I
A
V
P
H
G
T
-
V
E
AK
D
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
--
G
V
R
F
-
G
----
E
E
E
D
----
D
I
A
R
L
V
I
G
I
A
A
R
N
--
N
--
E
-
H
I
-
Q
-
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
K
-
44
Fugue
60.96
15%
-67
- C4 -
1XIZ
-
?
A:
[-1-153]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
Q
D
I
H
F
R
-----------
R
H
Y
-
V
R
H
L
P
K
E
V
S
Q
N
D
I
I
K
A
L
A
S
P
L
I
N
D
G
-
M
V
-
V
S
-----
D
F
A
D
H
V
I
T
R
E
Q
N
F
P
T
G
L
P
V
E
P
---
V
G
V
A
I
P
H
T
D
-
H
K
--
Y
--
V
R
Q
N
A
I
S
V
G
I
L
A
E
--
P
V
N
F
-
E
DMGG
E
P
D
P
----
V
P
V
R
V
V
F
M
L
A
L
G
E
--
S
--
N
K
Q
L
-
N
-
V
L
G
W
I
M
D
V
I
Q
D
E
D
F
M
Q
Q
L
L
V
M
N
D
D
E
I
Y
Q
S
I
Y
T
R
I
S
E
4
PsiBlast_PDB
60.59
38%
-67
- C4 -
2OQ3
-
PTMA_ECOLI
A:
[20-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
W
Q
E
A
I
D
F
S
M
V
S
L
L
D
K
N
-
Y
I
-
S
E
-----
N
Y
I
Q
A
I
K
D
S
T
I
N
N
G
P
Y
Y
I
L
-
A
---
P
G
V
A
M
P
H
A
R
-
P
E
--
C
G
-
A
L
K
T
G
M
S
L
T
L
L
E
Q
--
G
V
Y
F
-
P
GN--
D
E
P
-------
I
K
L
L
I
G
L
S
A
A
D
--
A
--
D
S
H
I
-
G
-
A
I
Q
A
L
S
E
L
L
C
E
E
E
I
L
E
Q
L
L
T
A
S
S
E
K
Q
L
A
D
I
I
S
R
G
--
26
HHSearch
60.40
20%
-63
- C4 -
3URR
4
?
A:
[5-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
A
K
I
L
P
-----------
L
E
N
-
V
V
I
G
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
E
N
Q
N
G
I
A
-
R
S
-----
T
V
T
D
N
L
F
A
R
-
E
R
L
G
S
-
T
G
L
-
G
---
E
G
V
A
I
P
H
G
R
-
I
K
---
G
-
L
K
H
P
L
A
A
F
V
R
L
A
E
--
P
I
P
F
-
E
----
A
P
D
G
----
Q
P
V
S
L
L
I
F
L
L
V
P
E
--
Q
AT
Q
A
H
L
-
E
-
I
L
S
E
I
A
Q
L
L
S
D
R
D
T
R
E
R
L
H
T
E
P
D
R
D
E
L
H
R
L
L
T
Q
W
Q
-
29
HHSearch
59.70
21%
-76
- C4 -
3T43
-
?
A:
[3-134]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
N
D
I
I
K
A
L
A
S
P
L
I
N
D
G
-
M
V
-
V
S
-----
D
F
A
D
H
V
I
T
R
-
E
Q
N
A
P
T
-
G
L
-
P
VEP
V
G
V
A
I
P
H
T
D
-
S
K
---
Y
-
V
R
Q
N
A
I
S
V
G
I
L
A
E
--
P
V
N
F
-
E
----
D
A
G
G
EPDP
V
P
V
R
V
V
F
M
L
A
L
G
N
--
W
--
F
D
I
T
-
N
-
V
L
W
W
I
M
D
V
I
Q
D
A
D
F
M
Q
Q
L
L
V
M
N
D
D
-
E
I
Y
Q
S
I
Y
T
R
I
-
22
HHSearch
57.05
29%
-2
- C4 -
2OQT
-
?
A:
[6-148]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
I
D
-----------
N
N
S
-
I
R
L
G
L
S
A
D
T
W
Q
E
A
V
R
L
A
V
Q
P
L
I
D
S
K
-
A
V
-
T
S
-----
A
Y
Y
D
A
I
I
A
S
T
E
K
Y
G
P
Y
Y
V
L
-
M
---
P
G
M
A
M
P
H
A
E
-
A
---
L
G
-
V
N
R
N
A
F
A
L
I
T
L
T
K
--
P
V
T
F
-
S
----
D
--
G
----
K
E
V
S
V
L
L
T
L
A
A
T
D
--
P
--
S
I
H
T
-
T
V
A
I
P
Q
I
V
A
L
F
E
L
D
N
A
I
E
R
L
V
A
C
Q
S
P
K
E
V
L
E
M
V
E
E
S
K
-
3
PsiBlast_PDB
56.46
29%
2
- C4 -
2OQT
-
?
A:
[3-141]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
Q
A
L
I
D
-----------
N
N
S
-
I
R
L
G
L
S
A
D
T
W
Q
E
A
V
R
L
A
V
Q
P
L
I
D
S
K
-
A
V
-
T
S
-----
A
Y
Y
D
A
I
I
A
S
T
E
K
Y
G
P
Y
Y
V
L
-
M
---
P
G
M
A
M
P
H
A
E
-
A
---
L
G
-
V
N
R
N
A
F
A
L
I
T
L
T
K
--
P
V
T
F
-
S
----
D
G
------
K
E
V
S
V
L
L
T
L
A
A
T
D
--
P
--
S
I
H
T
-
T
V
A
I
P
Q
I
V
A
L
F
E
L
D
N
A
I
E
R
L
V
A
C
Q
S
P
K
E
V
L
E
M
V
E
E
S
K
-