@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0219: (2015-11-29 )
MSYVVARMAKYKSGQLTAIYNHNERIFKNHSNKEIDVEKSHLNYELTNRDQAQNYHKQIKEHINENRLSTRGVRKDAILCNEWIITSDKTFFNSLDEKQTREFFDTAKDYFAEKYGDANIAYARVHLDESTPHMHLGIVPMKNGKLSSKALFGNKEKLVAIQDELPKYLNEHGFNLQRGEIGSKKKHLETAEFKEKQRLLDNADRKLADKHEELKALDDKISNVNDTIADKESRLKELEAKEWDAVGDLKQYELEKQSLAESIEDIKDIELLQLDRIQKEDLVKQSFDGKLKMDKETYNRLFQTASKHASSNAELKRDLVKAQSQNNHLSRELLNHRKTAEKNIKLSQENRKLKDKVKMLDEQVKILNKSLSVWKEKAKEFMPKQVYRETLSIINTLNPIGLAKTAIRQVKKMVDSNS
Atome Classification :
(20 SA)
------------------------------------------------------......---..--.10........20.-----------.......30....--....40......--------..50........60......----..70........80---........90---........100----.---......110.----.----.---.----------.-------.------------------------------------------.-120.....-..130--.-........140..---..---...--.150.......-160------------.......170.......180---------....---.....190........200.-------......210..--......220..-.....-230.......240-....--...250-----.......260.....-------..270.......------------280------.........290.......300....--...310.......320.......330--..--------.....340-.......350----------.......360.........370.......380.......390.......------400.......410......------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------M
S
Y
V
V
A
---
R
M
--
A
KYKSG
Q
L
T
A
I
YNH-----------N
E
R
I
F
KNHSNKE
I
--
D
V
EKSHL
N
Y
ELT--------
N
R
D
Q
A
Q
N
Y
H
K
Q
I
K
E
H
I
N
E
NR----LSTRGVRK
D
A
I
L
CN---
E
W
I
ITS
D
K
T
F
---
F
N
SL
D
E
K
Q
T
R
E
----
F
---
F
D
T
A
K
D
Y
F
A
E
----
K
----Y---G----------D-------A------------------------------------------
N
-
I
A
Y
A
R
V
H
L-DES----T-P
H
M
H
L
G
I
V
P-MKN---GK---LSS--KALFGNK
E
K
L
V
-
A
I
Q
------------
D
E
L
P
K
Y
L
N
E
HGFNLQRGE-----------IGSK---KKH
L
E
T
-
A
E
F
K
E
K
Q
R
L
L
DNA-------
D
R
K
L
A
D
K
-
H
E
E
--
L
K
A
L
D
D
K
ISNV-NDTIA-
D
K
E
S
R
L
K
E
L
E
AKE-WDAV--G
D
L
K
Q
Y
-----
E
L
E
K
Q
S
L
A
E
S
I
E
D
I
K
-------
D
I
E
L
L
Q
L
D
RI
Q
K
------------
E
--------
D
L
V
K
Q
SFDG
K
L
KM
D
K
E
T
Y
N
R
L
F
Q
T
A
S
--KHASS
N
A
E
L
K
R
D
L
V
K
A
QSQNN
H
L
S
R
E
--
L
L
--------
N
H
RKTAEK-N
I
K
LSQEN
R
K
----------
L
K
D
K
V
K
M
L
--
D
E
Q
V
K
I
L
N
K
S
L
S
V
W
K
E
K
A
K
EF
M
P
K
Q
V
Y
R
E
T
L
S
I
I
NTLNP------I
G
L
A
K
T
A
I
R
Q
V
K
K
M
VDSNS------------------------------------------
42
Fugue
92.02
62%
-62
- C5 -
4LVI
4
PRE_STRAG
A:
[1-194]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
----
V
S
N
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
K
R
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.51
62%
-65
- C5 -
4LVI
4
PRE_STRAG
A:
[1-192]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
V
----
S
N
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
K
R
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
90.84
62%
-74
- C5 -
4LVM
5
PRE_STRAG
A:
[1-192]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
V
------
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
K
R
A
M
A
D
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
90.79
62%
-67
- C5 -
4LVM
9
PRE_STRAG
C:
[1-191]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
V
F
E
T
H
S
N
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.79
62%
-64
- C5 -
4LVK
3
PRE_STRAG
A:
[1-192]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
V
----
S
N
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
K
R
A
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
89.49
62%
-62
- C5 -
4LVL
7
PRE_STRAG
A:
[1-192]
-------------------------------------------------------
S
Y
M
V
A
---
R
M
--
Q
K
M
K
A
G
N
L
G
G
A
F
K
H
-----------
N
E
R
V
F
E
T
H
S
N
K
D
I
--
N
P
S
R
S
H
L
N
Y
E
L
T
--------
D
R
D
R
S
V
S
Y
E
K
Q
I
K
D
Y
V
N
E
N
K
----
V
S
N
R
A
I
R
K
D
A
V
L
C
D
---
E
W
I
I
T
S
D
K
D
F
---
F
E
K
L
D
E
E
Q
T
R
T
----
F
---
F
E
T
A
K
N
Y
F
A
E
----
N
----
Y
---
G
----------
E
-------
S
------------------------------------------
N
-
I
A
Y
A
S
V
H
L
-
D
E
S
----
T
-
P
H
M
H
M
G
V
V
P
-
F
E
N
---
G
K
---
L
S
S
--
K
A
M
F
-
D
R
E
E
L
K
-
H
I
Q
------------
E
D
L
P
R
Y
M
S
D
H
G
F
E
L
E
R
G
K
-----------
L
N
S
E
---
A
K
H
K
T
V
-
A
E
F
K
R
A
M
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
56.98
17%
3
- C4 -
3VWA
-
CEX1_YEAST
A:
[1-540]
PLHMSISNFQFP
Y
T
I
E
ETAITETAL
W
Q
C
F
D
G
T
R
K
ADSL
P
V
T
V
F
K
A
KRSPEN
E
S
L
I
L
N
A
V
H
---
K
S
--
K
I
L
K
I
P
G
L
C
T
V
L
E
T
F
D
SDPQS
T
F
I
V
T
E
R
V
V
P
F
P
W
D
N
L
G
--
S
L
S
Q
N
K
F
G
V
E
L
G
--------
I
S
Q
L
L
A
T
L
G
F
-
L
K
N
F
V
--------
L
G
T
--
L
S
K
D
S
V
F
I
N
IKG
E
W
V
L
F
G
L
E
-
L
---
C
S
S
K
E
G
L
S
A
F
E
----
F
---
A
S
R
A
R
S
Y
Y
N
I
----
I
----
G
---
S
QLPCEDPNT
I
D
-------
S
M
-----------------------------------------
G
-
L
G
L
L
I
K
S
L
M
A
P
S
----
C
L
P
K
D
W
I
V
N
V
N
M
I
S
D
---
G
K
---
I
T
I
--
E
N
F
---
R
K
R
L
E
-
N
T
E
------------
T
W
R
S
N
P
L
I
N
F
Y
Q
E
L
R
E
L
H
-----------
I
K
D
P
---
Q
G
K
L
V
V
M
S
N
L
E
N
L
Y
L
E
S
R
E
I
-------
F
R
N
L
T
P
G
M
I
E
N
F
I
I
P
E
L
C
E
I
I
K
L
L
M
T
Q
S
I
S
S
N
A
S
H
K
L
V
P
F
L
A
I
V
-
L
D
L
T
--
S
E
T
N
T
F
PVG
F
N
D
L
I
T
Q
S
F
K
L
P
D
R
Q
V
R
-------
F
L
L
L
I
Y
L
P
K
L
I
G
PLS
K
S
E
I
S
S
RI
Y
P
--------
H
F
I
Q
G
L
T
D
S
D
A
T
L
R
L
Q
T
L
K
T
I
P
C
I
V
S
CL
T
E
R
Q
L
N
N
E
L
L
R
F
L
A
K
T
Q
V
D
S
D
V
E
I
R
T
W
T
V
I
--------
I
I
S
K
I
S
T
I
L
S
T
S
V
G
N
R
S
N
I
----------
L
A
T
A
F
T
K
S
L
K
D
P
Q
V
K
P
R
L
A
A
L
Y
G
L
E
K
S
I
E
L
F
D
V
N
T
I
A
N
K
I
L
T
V
I
A
P
G
L
L
DKS
P
I
V
R
G
R
A
K
I
L
F
E
E
Y
L
E
K
L
E
K
E
A
Q
L
IQTN------------------------------------
40
HHSearch
55.21
20%
-38
- C- -
3L6T
20
?
A:
[81-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
R
L
G
Y
---
D
L
T
F
S
A
P
K
G
V
SMQ
A
L
I
H
G
D
K
T
I
I
E
A
H
E
K
A
---
V
A
A
A
V
R
E
A
E
K
L
A
Q
A
R
----
T
T
R------------
K
S
V
T
Q
NTN
N
------------------------------------------
L
-
V
V
A
T
F
R
H
E
-
T
S
R
AL
D
P
D
-
L
H
T
H
A
F
V
M
N
-
M
T
Q
R
ED
G
Q
W
R
A
L
K
N
--
D
E
L
M
R
N
K
M
H
L
G
D
V
Y
K
------------
Q
E
L
A
L
E
L
T
K
A
G
Y
E
L
R
Y
N
S
-----------
K
N
N
T
---
F
D
M
A
H
F
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
55.11
17%
15
- C3 -
4XDN
5
SCC4_YEAST
A:
[24-640]
------------------------------------G
D
K
L
S
I
S
Q
V
Y
H
L
A
Q
E
Y
R
D
H
A
Y
S
I
A
---
N
K
IG
S
E
E
G
L
K
Q
Y
Y
G
L
M
N
M
-----------
S
I
Q
M
F
Q
L
L
K
T
K
C
T
LS
V
L
E
D
S
K
V
T
F
E
M
V
E
L
L
I
Q
ETY
N
F
D
L
A
E
L
Y
I
S
S
L
K
E
R
L
Q
T
H
Q
SDTD
L
V
E
E
I
M
R
C
E
F
L
L
L
H
---
D
L
P
L
M
R
D
S
K
F
---
H
Y
K
I
A
L
R
N
C
N
E
----
L
---
V
Q
Y
M
V
N
L
Q
D
E
----
L
----
Y
---
Q
----------
N
-------
W
A
S
V
F
Q
Y
V
G
V
M
L
C
I
K
L
KQ
H
R
R
V
K
T
S
F
H
G
L
L
S
Q
CREKS
Q
W
K
W
F
L
N
-
L
C
Y
V
N
Y
L
L
-
N
E
R
----
F
-
P
I
P
E
D
A
L
Q
E
-
L
R
S
---
T
E
---
L
H
T
VG
P
E
L
Y
A
W
K
L
A
L
E
-
M
V
I
Q
L
C
K
DGNI
T
D
H
L
N
E
F
K
N
F
F
D
T
N
K
Q
S
L
V
T
N
E
GKGCVIKIMPR
I
A
L
K
V
E
L
P
M
I
F
H
Y
-
K
E
L
K
N
I
L
L
L
L
Q
S
V
S
Y
I
VNCY
D
E
K
G
N
F
S
-
R
K
F
--
L
P
K
V
Y
S
T
T
Q
K
L
-
I
K
N
I
A
-
A
G
G
V
S
M
N
E
L
D
S
R
I
-
Q
T
Y
K
--
S
I
L
E
F
C
-----
E
F
Y
K
V
W
E
Q
T
L
L
K
G
A
V
VLGPSPG
Y
V
R
L
L
Q
A
M
K
V
Q
F
------------
E
GGGA
V
E
E
Y
T
R
L
A
Q
S
G
G
T
S
S
E
V
K
M
I
S
L
L
N
C
Y
T
V
Q
A
--
A
R
V
S
R
C
S
G
D
K
Q
G
E
L
V
E
Q
C
N
K
V
W
L
Q
V
E
--
K
L
L
Q
E
T
DLQF
N
P
I
W
E
C
T
V
-
T
I
L
W
L
F
S
H
F
E
PFSWNPLPCS
D
K
Q
R
A
E
Y
V
--
S
K
L
R
E
F
Y
S
S
N
K
F
V
N
R
F
K
L
K
K
A
L
L
L
Q
I
L
V
N
Y
L
G
G
R
M
L
E
H
D
------
L
G
E
I
Y
A
I
S
A
K
C
F
D
M
C
R
Q
Q
G
GM
R
K
V
Q
Y
V
I
G
I
W
H
L
M
N
C
T
V
A
MR
G
K
D
V
A
L
T
N
A
K
L
E
A
L
V
K
Q
I
T
S
46
Fugue
50.87
17%
64
- C5 -
3Q8T
-
BECN1_RAT
A:
[172-265]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
D
S
-
E
Q
L
Q
R
E
L
K
E
L
A
L
E
-------
E
E
R
L
I
Q
E
-
L
E
D
--
V
E
K
N
R
K
V
V
A
E
N
-
L
E
K
V
Q
-
A
E
A
E
R
L
D
Q
E
E
A
Q
Y
-
Q
R
E
Y
--
S
E
F
K
R
Q
-----
Q
L
E
L
D
D
E
L
K
S
V
E
N
Q
M
-------
R
Y
A
Q
M
Q
L
D
K
L
K
K
------------
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
50.64
15%
79
- C5 -
1NYH
-
SIR4_YEAST
A:
[1271-1346]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
F
V
D
I
V
L
S
K
A
-------
A
S
A
L
D
E
K
-
E
K
Q
--
L
A
V
A
N
E
I
I
R
S
L
-
S
D
E
V
M
-
R
N
E
I
R
I
T
S
L
Q
G
D
L
-
T
F
T
K
--
K
C
L
E
N
A
-----
R
S
Q
I
S
E
K
D
A
K
I
N
K
L
M
-------
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
49.15
9%
36
- C2 -
2FEN
1
?
A:
[2-350]
------------------------------------------------------
S
L
S
P
F
E
HPF
L
S
--
G
L
F
G
D
S
E
I
I
E
L
F
S
------------
A
K
A
D
I
D
A
M
I
R
F
E
T
--
A
L
A
Q
A
E
A
E
A
S
I
F
--------
A
D
D
E
A
E
A
I
V
S
G
L
S
E
F
------------------------------
A
A
D
M
S
A
---
L
R
H
G
V
A
K
D
G
V
V
----
V
---
P
E
L
I
R
Q
M
R
A
A
----
V
----
A
---
G
----------
Q
-------
A
------------------------------------------
A
-
D
------------------
K
V
H
F
G
A
---------------------------
T
S
Q
-
D
V
I
------------
D
T
S
L
M
L
R
L
K
M
A
A
E
I
I
A
T
R
-----------
L
G
H
L
---
I
D
T
L
G
D
-
L
A
S
R
D
G
H
K
P
L
T
G
Y
-------
T
R
M
---
Q
-
A
A
I
--
G
I
T
V
A
D
R
A
A
G
W
-
I
A
P
L
E
-
R
H
L
L
R
L
E
T
F
A
Q
N
G
---
F
A
--
L
Q
F
G
G
A
-----
A
G
T
L
E
K
L
G
D
N
A
G
A
V
R
-------
A
D
L
A
K
R
L
G
L
A
D
R
------------
P
--------
Q
W
H
N
Q
---------
R
D
G
I
A
E
F
A
N
L
L
S
--
L
V
T
G
T
L
G
K
F
G
Q
D
I
A
L
M
A
E
I
G
S
E
I
R
L
S
--
G
G
--------
G
K
Q
N
---------
P
V
N
A
E
T
----------
L
V
T
L
A
R
F
N
--
A
V
Q
I
S
A
L
H
Q
S
L
V
Q
E
Q
E
R
S
G
A
G
W
M
L
E
W
L
T
L
P
Q
M
V
T
A
T
G
T
S
------
L
L
V
A
E
R
L
A
A
Q
I
D
R
L
G
A
---------------------------------------------
29
HHSearch
48.77
16%
86
- C5 -
3VKG
-
?
A:
[2034-2097]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
T
I
T
A
L
E
K
S
I
A
T
Y
K
E
E
--
Y
-----------
A
T
L
I
R
E
-
T
E
Q
I
K
T
E
S
S
K
----------
V
K
N
K
V
D
R
S
--
I
A
L
L
D
N
L
N
S
E
R
G
R
W
E
Q
Q
S
E
N
F
N
T
Q
M
S
T
V
V
G
D
V
V
L
A
S
A
F
L
------
A
Y
I
G
F
F
D
Q
N
F
R
T
D
L
M
R
K
W
M
------------------------------------------
37
HHSearch
48.08
16%
-59
- C5 -
1OMH
4
?
A:
[79-213]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
R
I
G
L
---
D
L
T
F
S
A
P
K
S
V
S
L
Q
A
L
V
A
G
D
A
E
I
I
K
A
---
H
D
R
A
V
A
R
T
L
E
Q
A
E
A
----
R
A
Q
A
R
Q
K
I
Q
G
----------
K
T
R
I
E
TT-
G
------------------------------------------
N
L
V
I
G
K
F
R
H
E
-
T
S
R
ERDP
Q
-
L
H
T
H
A
V
I
L
N
-
M
T
K
R
SD
G
Q
W
R
A
L
K
N
--
D
E
I
V
K
A
T
R
Y
L
G
A
V
Y
N
------------
A
E
L
A
H
E
L
Q
K
L
G
Y
Q
L
R
Y
G
K
-----------
D
G
N
F
---
D
L
A
H
I
D
-
R
Q
Q
I
E
G
F
S
K
R
T
E
Q
-------
I
A
E
W
Y
A
A
-
R
G
L
--
D
P
N
S
V
S
L
E
Q
K
Q
-
A
A
K
V
L
-
S
R
A
K
K
T
S
V
D
R
E
A
L
-
R
A
E
W
--
Q
A
T
A
K
E
-----
L
G
I
D
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
47.26
14%
129
- C5 -
3E7K
-
TRPM7_RAT
A:
[2-55]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
---
G
S
R
V
T
F
-
E
R
V
E
Q
M
S
I
Q
I
K
E
V
-------
G
D
R
V
N
Y
I
-
K
R
S
--
L
Q
S
L
D
S
Q
I
G
H
L
-
Q
D
L
S
A
-
L
T
V
D
T
L
K
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
43.38
27%
125
* C5 *
2EFR
-
GCN4_YEAST (first)
A:
[243-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
S
V
T
K
L
E
K
S
I
D
D
L
E
D
E
--
L
-----------
Y
A
Q
K
L
K
-
Y
K
A
I
S
E
E
M
K
Q
----------
L
E
D
K
V
E
E
L
--
L
S
K
N
Y
H
L
E
N
E
------------------------------------------------------------------------------------------------
31
HHSearch
41.97
25%
198
- C5 -
2J5U
-
MREC_LISMO
A:
[74-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
N
Q
H
L
K
E
R
--
L
E
--------
E
L
A
Q
L
E
S
E
-
V
A
D
L
K
K
E
N
K
D
----------
L
K
E
S
L
D
--------------------------------------------------------------------------------------------------------------
45
Fugue
41.39
24%
117
- C5 -
1DEB
-
APC_HUMAN
A:
[1-54]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
A
S
Y
D
Q
L
L
K
Q
V
E
A
L
K
M
E
N
S
N
L
R
Q
E
--
L
-----------
E
D
N
S
N
H
-
L
T
K
L
E
T
E
A
S
N
----------
M
K
E
V
L
K
Q
L
--
Q
G
S
I
------------------------------------------------------------------------------------------------------
24
HHSearch
40.84
25%
147
- C5 -
1DEB
-
APC_HUMAN
A:
[7-50]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
L
K
Q
V
E
A
L
K
M
E
N
S
N
L
R
Q
E
--
L
-----------
E
D
N
S
N
H
-
L
T
K
L
E
T
E
A
S
N
----------
M
K
E
V
L
K
Q
L
--
Q
G
S
I
------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
40.10
30%
78
- C5 -
1IPH
-
CATE_ECOLI
A:
[279-381]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
N
A
-------
E
G
K
A
T
F
V
-
R
F
H
--
W
K
P
L
A
G
K
A
S
L
V
-
W
D
E
A
Q
-
K
L
T
G
R
D
P
D
F
H
R
R
E
L
W
E
A
I
E
A
G
D
F
P
E
Y
-----
E
L
G
F
Q
L
I
P
E
E
D
E
F
K
F
-------
D
F
D
L
L
D
P
T
K
L
I
P
------------
E
--------
E
L
V
P
V
Q
R
V
G
K
M
V
L
N
R
N
P
D
N
F
F
A
E
N
E
Q
--
A
A
F
H
P
G
H
I
V
P
G
L
D
F
T
N
D
P
L
L
Q
G
R
L
F
S
--
Y
T
--------
D
T
Q
I
S
R
L
G
-
G
P
N
F
H
E
I
P
I
N
----------
R
P
T
C
P
Y
H
N
--
F
Q
R
D
G
M
H
R
M
G
I
D
T
N
P
A
N
Y
E
P
N
S
I
N
D
N
W
P
R
E
T
P
P
G
P
K
R
G
G
------
F
E
S
Y
Q
E
R
V
E
G
N
K
V
R
E
R
S
P
S
------------------------------------------