@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0272: (2015-11-29 )
MSREYITLSKNIIKHLGGQNNINNVYHCQTRLRFSLNDPTKVNLEQLKTLKEVKTVVISGGQHQIVIGTHVAKVFEEINSLIETNSTTKTEQTKKAKAVSRIIDFVSGTFQPILPALSGAGMIKALLALLLVFKILTPLSQTYILLNLFADGVFYFLPILIAITAAQKLKANPILALGTVVMLLHPNWANLVASGKPVSLFHTIPFTLTNYASSVIPIILIICVQAYIEKYLNQIIPKSLRLVLVPMLIFLSMGILSFSILGPMGTIAGQYLAVIFTFLSKYASWAPAFLVGAFAPILIMFGVHSGIAALGITQLTKLGFDSIFGPGMLCSNIAQATAGTVVTLITKEKKLKEIAGPAAITAYMGITEPILYGVNLPKRYPLIASLIGGGLGGLYAGIMNAHRFAVGSSGLPGLFLYISHTSTHLFITMLIAVIITVSTTAILTFILAQYYEKQVSIRQRD
Atome Classification :
(20 SA)
--.........10........20.......-.30.---.......40.......-.50.-----.......60......-.---.-70..-.......-------80........90........100.......-110--.-....----..120........130.--.....--.140.......150........160----.....-------..170.......180---.......190....--.-..200........210.......220-.......230..-----.....240.-------......250........260.......270....-...280....-----....290-....-....300......--.-310---...----..--...320-.....--...330........340------..----...--....350.......360----.......370.-.....----.--380.......390.......400.......-------410....------....420........430.......440.....-..450........460---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MSR
E
Y
I
T
L
S
K
N
I
I
K
H
LGGQNNIN
N
V
Y
H
C
-
Q
T
R
L
---
R
F
SLNDPTKV
N
L
E
Q
L
K
-
T
L
K
E
-----
V
K
T
V
V
ISGG
Q
H
Q
I
V
I
-
G
---
T
-
H
-
V
A
-
K
V
F
E
E
I
N
-------
S
L
I
ETNSTTK
T
E
Q
T
K
K
A
K
A
V
S
R
I
I
D
F
V
S
G
T
-
F
Q
P
--
I
-
L
P
AL----SG
A
-
G
M
I
K
A
L
L
A
L
L
L
V
F
--
K
I
LT
P
--
L
S
Q
T
Y
I
L
L
N
L
FAD-
G
V
F
Y
F
L
P
I
L
I
A
----
I
T
A
A
Q
-------KLKAN
P
I
L
A
L
G
T
V
V
M
---
L
LHP
N
W
A
N
LVASGK--
P
-
V
S
L
-
F
H
TIP
F
T
L
T
N
Y
A
S
S
V
I
P
I
I
L
I
I
-
C
V
Q
A
Y
I
E
K
Y
L
N
Q
-----
I
I
P
K
S
L
R
L
V
-------
L
V
P
M
L
I
F
L
-
S
M
G
I
L
S
F
SILG
P
M
G
T
I
A
G
Q
Y
L
A
V
I
F
-
T
F
L
S
K
-YASW-----
A
P
A
F
L
V
--
G
A
F
A
-
P
I
L
I
M
F
GVH
S
G
I
A
--
A
-
L
G
----
I
T
Q
----
L
T
--
K
LG
F
D
--SIFG
P
--
G
M
L
C
-
S
N
I
A
Q
ATA
G
T
--------
V
V
----
T
L
I--T
K
E
K
K
L
K
E
IA
G
P
A
A
I
T
A
----
Y
MGI
T
E
P
I
L
YG-VNLPK----R--
Y
P
L
I
A
S
L
I
GG
G
L
G
G
L
Y
A
G
I
M
N
A
H
R
FAVGSS-------GL-
P
G
L
F
------
L
Y
I
SHT-S
T
H
L
F
I
T
M
L
I
A
V
I
I
TV
S
T
T
A
I
L
T
F
I
L
-
A
Q
Y
-
Y
E
K
Q
VSIRQRD----------
27
Fugue
70.41
19%
-77
- C2 -
4UQU
10
?
A:
[1-462]
AE
K
E
K
N
A
A
E
I
R
Q
Q
F
A
M
T
A
G
S
P
I
I
V
N
D
K
L
E
R
-
Y
A
E
V
---
R
T
A
F
T
H
P
T
S
F
F
K
P
N
Y
K
G
E
V
K
P
-----
W
F
L
S
A
Y
D
E
K
V
R
Q
I
E
N
-
G
---
E
-
N
-
G
P
-
K
---------------
M
K
A
K
N
V
G
E
A
R
A
G
R
A
L
E
A
A
G
W
T
L
D
I
N
Y
G
N
-
I
Y
P
NR
F
-
F
M
L
W
----
S
G
E
-
T
M
T
N
T
Q
L
W
A
P
V
G
L
--
D
R
R
P
P
--
D
T
T
D
------------------
P
V
E
----
L
T
N
Y
V
-------
K
F
A
A
R
M
A
G
A
D
L
V
G
V
A
---
R
L
N
R
N
W
V
----
Y
S
E
--
A
-
V
T
I
-
P
A
D
V
P
Y
E
Q
S
L
H
K
E
I
E
K
P
I
V
F
K
--
D
V
P
L
P
I
E
T
D
D
E
L
-----
I
I
P
N
T
C
E
N
V
-------
I
V
A
G
I
A
M
N
-
R
E
M
M
Q
T
A
P
-----
N
S
M
A
C
A
T
T
A
F
C
Y
-
S
R
M
C
M
-
F
D
M
W
-----
L
C
Q
F
I
R
Y
M
G
Y
Y
A
I
P
S
C
N
G
V
G
Q
S
V
A
F
A
--
V
E
A
G
----
L
G
Q
----
A
S
--
R
M
G
A
C
IT
P
E
F
G
P
--
N
V
R
L
-
T
K
V
F
T
N
M
P
L
V
P
D
K
P
I
D
FG
V
T
----
E
F
C
--
E
T
C
K
K
C
A
R
E
C
P
S
K
A
I
T
E
G
P
R
T
F
E
G
R
S
I
H
N
Q
S
G
K
L
Q
W
Q
N
----
D
--
Y
N
K
C
L
G
Y
W
P
E
S
-
G
G
Y
C
G
V
C
V
A
V
C
P
F
T
K
G
N
I
-------
W
I
H
D
G
V
E
------
W
L
I
D
N
T
-
R
N
----------
I
T
E
V
W
D
G
K
I
N
T
Y
G
L
D
A
D
H
-
F
R
D
T
V
S
F
R
K
D
R
VK--------
23
Fugue
68.52
15%
-113
- C1 -
4C1N
2
?
A:
[1-442]
---
G
L
T
G
L
E
I
Y
K
H
L
P
K
K
N
C
K
E
C
G
Q
P
T
C
L
A
F
-
A
M
Q
I
A
A
G
K
A
G
L
D
A
C
P
Y
V
S
D
E
A
K
E
-
L
L
E
S
A
S
APP
V
A
L
I
K
V
G
K
G
E
K
V
L
E
I
-
G
---
H
-
E
-
T
V
-
L
F
R
H
D
K
R
FEH
P
C
G
L
A
I
L
V
E
D
T
L
S
E
G
E
I
K
E
R
V
E
K
I
N
K
L
V
F
D
R
V
G
Q
-
M
H
S
--
V
N
L
V
A
L
----
K
G
S
S
Q
D
A
A
T
F
A
K
A
V
A
T
A
--
R
E
V
T
D
--
L
P
--
F
I
L
I
G
T
----------
P
E
Q
L
A
----
A
A
L
E
T
-------
E
G
A
N
N
P
L
L
Y
A
A
T
--------
A
D
N
Y
E
Q
M
V
E
L
A
K
--
K
------
Y
N
V
P
L
T
V
S
A
K
G
L
D
A
L
A
E
L
V
Q
K
-
I
T
A
L
G
Y
K
N
L
I
L
D
-----
P
Q
P
E
N
I
S
E
G
-------
L
F
Y
Q
T
Q
I
R
-
R
L
A
I
K
K
--
L
F
R
P
F
G
Y
P
T
---
I
A
F
A
L
-
D
E
N
P
Y
-
Q
A
V
M
-----
E
A
S
V
Y
I
--
A
K
Y
A
-
G
I
I
V
L
----
N
T
V
E
--
P
-
A
D
----
I
L
P
----
L
I
--
T
L
R
L
N
--
I
Y
T
D
P
--
Q
----------------------------
K
P
I
--
A
V
E
P
K
V
Y
E
I
L
N
P
-----------
G
P
D
A
P
V
F
I
T
-
T
N
F
S
L
----
T
--
Y
F
C
V
A
G
D
V
E
G
A
R
I
P
A
Y
I
L
P
V
D
T
D
G
T
S
V
L
T
A
-------
W
A
-
A
G
K
F
T
P
E
K
I
A
Q
F
L
K
E
S
-
G
I
A
E
K
V
N
H
R
K
A
I
L
P
G
G
V
A
V
L
S
G
K
L
Q
E
-
L
S
G
-
W
E
I
L
V
G
P
R
E
S
S
G
I
N
S
F
I
K
Q
RW
22
Fugue
68.07
22%
-69
- C2 -
4PE6
1
?
A:
[18-339]
----
K
P
F
I
A
L
S
N
G
F
I
G
--------
N
G
W
R
Q
T
M
I
A
K
F
---
E
E
A
A
K
Q
A
Q
A
------
D
-
G
L
I
G
-----
K
Y
K
V
V
N
A
P
G
N
N
S
------------
A
T
-
E
Q
V
A
Q
I
K
-------
S
L
L
L
Q
K
P
D
------------
A
L
L
I
N
P
A
S
P
T
A
L
Q
P
--
V
-
I
Q
Q
A
----
C
D
A
-
G
V
------
K
V
V
V
F
--
D
S
A
I
D
--
A
P
C
A
Y
I
L
Q
N
S
F
V
D
-
W
A
T
Y
A
A
K
P
V
L
E
----
S
I
G
G
K
-----------------
G
N
V
I
V
---
V
R
G
------
V
V
G
S
Q
--
P
-
E
A
E
M
Y
E
T
T
K
K
I
L
A
E
Y
P
Q
V
K
T
V
A
T
V
T
G
M
C
D
G
A
T
A
Q
K
A
V
L
G
-----
V
L
P
S
V
S
T
----------
V
D
A
V
I
----------------
G
C
G
D
G
Y
G
V
A
Q
A
F
-
A
T
A
G
K
---------------------
P
-
I
P
A
V
T
F
E
T
N
--
G
R
--
A
-
L
S
----
Y
W
K
----
D
N
--
K
I
D
N
G
--
S
V
A
-------
V
M
S
D
P
A
Q
S
V
A
A
L
--------
W
A
----
A
L
D
--
L
L
E
----------------------------
G
-
R
D
L
P
K
----
Q
M
T
F
P
I
V
--
L
I
E
E
K
D
R
D
T
W
A
S
V
L
K
P
D
E
Y
A
---------------------------
A
W
P
-
W
T
R
E
L
F
R
Q
Q
V
E
A
I
K
T
G
G
E
P
--------------
V
Q
P
P
I
P
S
T
-----------
25
Fugue
64.28
12%
-101
* C4 *
3QNQ
8
?
A:
[3-434]
--------------------------
R
F
L
E
-
K
Y
V
M
---
P
V
A
G
K
V
A
E
Q
R
H
L
L
A
I
R
-
D
G
L
V
-----
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
-
S
---
T
-
L
-
P
I
-
P
G
Y
S
E
F
M
-------
A
S
L
F
G
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
L
I
A
V
F
G
-
I
A
Y
--
R
-
L
G
E
Y
----
Y
K
V
-
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
A
T
P
--
F
Q
V
A
Y
I
M
P
G
---
T
-
K
E
S
I
L
V
D
G
V
I
P
----
A
A
----------
L
M
G
S
Q
G
L
F
V
A
M
I
I
A
I
---
I
S
T
E
I
Y
R
F
L
V
Q
K
K
M
--
I
-
I
K
M
-
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
F
I
V
V
-
T
V
V
W
I
I
R
L
I
F
E
H
-----
T
T
F
G
S
I
H
N
V
-------
V
G
K
L
L
-------------
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
-
A
V
I
L
V
-
H
V
L
W
A
C
GIH
G
A
T
I
V
G
--
G
V
M
S
-
P
I
W
L
S
L
M
D
Q
N
R
I
A
--
F
-
Q
A
----
G
Q
D
----
V
P
--
N
T
I
T
A
--
Q
F
F
D
L
--
W
I
Y
M
-
G
G
S
G
-
A
T
L
A
L
--------
V
V
----
G
M
L
L
F
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
----
I
F
N
I
N
E
M
V
T
F
G
-
M
P
I
V
M
----
N
--
P
L
L
L
I
P
F
I
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
P
SGAAVTW
T
T
-
P
I
L
F
------
S
G
Y
L
G
S
-
G
G
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
-
I
W
D
-
K
Q
K
I
A
E
E
K
G
E
A
----------
2
PsiBlast_PDB
61.75
33%
-76
- C3 -
1O2F
-
PTGCB_ECOLI
B:
[315-388]
---------
M
A
A
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
G
------
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
60.60
31%
-81
- C3 -
3BP3
1
PTGCB_ECOLI
A:
[2-81]
-----
G
T
S
E
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
-
G
-----
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
60.55
33%
-92
- C3 -
3BP3
1
PTGCB_ECOLI
A:
[10-81]
-------------
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
G
------
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
59.59
32%
-69
- C3 -
3IPJ
2
?
B:
[3-92]
---
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
-
A
T
R
L
---
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
-
K
V
D
E
-----
V
K
G
V
F
F
T
S
G
Q
Y
Q
I
I
L
-
G
---
T
-
G
-
I
V
N
K
V
Y
A
E
V
E
-------
K
M
-
G
L
K
T
L
S
K
K
E
Q
D
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
59.02
32%
-57
- C3 -
3IPJ
1
?
A:
[3-92]
---
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
-
A
T
R
L
---
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
-
K
V
D
E
-----
V
K
G
V
F
F
T
S
G
Q
Y
Q
I
I
L
-
G
---
T
-
G
-
I
V
N
K
V
Y
A
E
V
E
-------
K
M
-
G
L
K
T
L
S
K
K
E
Q
D
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
57.94
33%
-50
- C3 -
3IPJ
1
?
A:
[3-87]
---
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
-
G
E
D
N
I
I
S
I
T
H
C
-
A
T
R
L
---
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
-
K
V
D
E
-----
V
K
G
V
F
F
T
S
G
Q
Y
Q
I
I
L
-
G
---
T
-
G
I
V
N
-
K
V
Y
A
E
V
E
-------
K
M
G
L
K
T
L
S
K
K
E
Q
D
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
57.24
33%
-87
- C3 -
3BP8
-
PTGCB_ECOLI
C:
[1-74]
---------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
G
------
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
57.15
31%
-50
* C3 *
3IPJ
1
?
A:
[1-95]
-S
N
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
-
A
T
R
L
---
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
-
K
V
D
E
-----
V
K
G
V
F
F
T
S
G
Q
Y
Q
I
I
L
-
G
---
T
G
I
-
V
N
-
K
V
Y
A
E
V
E
-------
K
M
G
L
K
T
L
S
K
K
E
Q
D
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
54.71
13%
-115
- C4 -
3QNQ
8
?
A:
[14-428]
------------------------------------------------------------------------------------------------------------------------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
-
L
V
L
--
T
-
M
P
F
L
----
I
I
G
-
S
I
F
L
I
I
S
T
L
P
I
P
G
Y
S
E
F
M
A
S
L
F
G
K
N
W
N
V
A
L
G
Y
P
V
S
-
A
T
F
N
I
M
A
L
I
A
V
F
G
I
A
Y
R
L
G
E
-------
Y
Y
K
V
D
A
L
A
S
G
A
L
S
L
V
T
F
L
L
A
T
P
F
Q
V
A
Y
I
M
P
G
T
K
E
S
I
L
V
D
-
G
-
V
I
P
A
A
L
M
G
-
S
Q
G
L
F
V
A
M
I
I
A
-
I
I
S
T
E
I
Y
R
F
L
V
Q
K
KM
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
F
E
H
T
T
F
G
S
I
H
N
V
V
G
K
L
L
Q
E
P
L
S
I
L
G
A
S
L
-----
W
G
A
V
I
A
--
V
I
L
V
-
H
V
L
W
A
C
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
F
Q
A
G
Q
D
VP
N
T
I
T
A
QF
F
D
L
W
-
I
Y
M
G
G
S
G
A
T
L
--------
A
L
V
V
G
M
L
L
F
--
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
----
I
F
N
I
N
E
M
V
T
F
G
-
M
P
I
V
M
NP
L
L
L
--
I
P
F
I
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
P
S
G
A
A
-------
V
T
-
W
T
T
P
------
I
L
F
S
G
Y
L
G
S
G
G
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
-
L
K
I
W
D
K
Q
K
I
A
E
E
K
G
E
----------
3
PsiBlast_PDB
50.35
33%
-44
- C3 -
1IBA
-
A:
[15-88]
---------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
G
------
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
N
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
50.12
30%
-36
- C3 -
1IBA
-
A:
[15-92]
---------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
-
G
-----
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
N
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
49.46
39%
-40
- C3 -
3BP3
1
B:
[10-66]
-------------
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
-
I
T
R
L
---
R
V
S
V
A
D
V
S
K
V
D
Q
A
G
L
K
-
K
L
G
------
A
A
G
V
V
V
A
G
S
G
V
Q
A
I
F
-
G
---
T
-
K
-
S
D
-
N
L
K
T
E
M
D
-------
E
Y
I
R
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.60
24%
-67
- C3 -
3HRX
-
?
A:
[13-173]
---------------------------------------
L
T
L
N
R
P
E
K
L
N
A
I
T
G
E
-
L
L
D
A
-----
L
Y
A
A
L
K
E
G
E
E
D
R
E
V
R
-
A
L
L
L
T
-
G
-
A
G
-
R
A
F
S
A
G
Q
-------
D
L
T
E
F
G
D
R
-
K
P
D
Y
E
A
H
L
R
R
Y
N
R
V
V
E
A
L
S
G
L
-
E
K
P
--
L
-
V
V
A
V
N
G
V
A
A
G
A
-
G
M
S
L
A
L
W
G
D
L
R
L
A
--
A
V
G
A
S
--
F
T
T
A
F
V
R
I
G
L
V
P
D
S
G
L
S
F
L
L
P
R
L
V
G
----
L
A
K
A
Q
E
L
L
L
L
SP
R
L
S
A
E
E
A
L
A
L
G
L
V
H
R
---
V
V
P
A
E
K
L
M
E
E
A
L
S
L
--
A
-
K
E
L
-
A
Q
G
P
T
R
A
Y
A
L
T
K
K
L
L
L
E
T
Y
R
L
S
-
L
T
E
A
L
A
L
E
A
V
L
Q
-----
G
Q
A
G
Q
T
Q
D
H
-------
E
E
G
V
R
A
F
R
-
E
K
R
P
P
R
F
Q
G
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
35.05
16%
-16
- C4 -
2N2H
-
?
B:
[1-125]
---------------------
S
N
A
E
H
I
Y
R
C
-
E
D
-
E
---
R
F
E
L
D
V
V
L
E
T
N
L
A
T
I
R
-
V
L
E
A
-----
I
Q
K
K
L
S
R
L
S
--------------------
A
E
E
Q
A
-------
K
F
R
L
D
N
T
L
G
G
T
S
E
V
I
H
R
K
A
L
Q
R
I
Y
A
D
K
A
A
D
-
I
I
D
--
G
-
L
R
K
N
----
P
S
I
-
A
V
P
I
V
L
K
R
L
K
M
K
E
--
E
E
W
R
E
--
A
Q
R
G
F
N
K
V
W
R
E
Q
N
-
E
K
Y
Y
L
K
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
25.09
16%
77
* C2 *
3E56
-
?
A:
[13-87]
----------------------
L
E
V
G
V
Y
E
C
-
E
I
H
L
---
K
F
R
L
I
E
E
K
S
L
L
S
D
R
E
Q
-
L
L
Q
V
-----
L
L
D
A
L
T
E
G
S
D
D
F
--
L
-
E
---
T
-
L
-
Q
A
-
S
V
K
A
Q
E
V
-------
S
E
F
K
A
S
P
Q
M
R
R
Q
L
M
R
L
R
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
24.23
19%
102
- C3 -
3CCD
1
PTHP_ECOLI
A:
[40-83]
---------------------------------------------
K
S
A
S
A
K
S
L
F
-
K
L
-
Q
-----
T
L
G
L
-
T
Q
G
T
V
V
T
I
S
A
E
G
---
E
-
D
-
E
Q
-
K
A
V
E
H
L
V
-------
K
L
M
A
E
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------