@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0384: (2015-11-30 )
MDVSSSPNITFMLQYTEANPQYVDYTNREEAVKIDEELSLETNRQMIEGLTEDELTRIQEAVPETQLNFREYIDYMNRSYATEEQSKELTAIFTQEADYLQKLRLIDLKNKLESAYQNGSLLWQGVISFDNAFLAEQGLYDVATGQVDQKAIKAVMRDMMPTLIQKEGLSDSAFWWGNIHLNTDNIHIHFGLSEVESNREKIFYQPRGRMEYKGNFSQKTINRFKSGVYHGLLKEETRSNLLRKEQILANLKADFITSIYQKDKITSSAEKNFLEQAYNHLPLNKKWRYGSNARDFAVSKFFLDRYLDSYLNNEGSAAYQEFLKETRDFLQTYEGVYSAEKNKIYEKLRKVDGQTIRTLAESKGYDLEHHLARRVMDLRERLANNILRSFREAAPQIQDVQLEKNLESFSVLNQKKILEQHPEASVVKSQKAWQKLGYFVKAGEQPLEIIRPVYKSYDKHGKGIGRPEFVSDTVYDISQLTENIQLKSLTLKDLSLFSSNELKELVDAAKLKTNPTERERRELGTYRYALKLSILESSQKELQVRQKLLEQVQPLASDQPFLDFKKQLIAQELQAIALQLTPNYKLSEDDKALKNRLKRQFEDSVALPVSKATPGAIQLPIRQLWTELGLVHHIQDENILTLLKGTSTTKQAYIEELQTHISIFQLKYQINNRNKQISQLSDEATIKEMRIANAKGFSELKRLYDTLQPSDDGQNQISQAVSKQLQERKVIKKAQLQQTQRSGKINTDFMRQLTASLNRSQQASKKALMERARSDEREEQEERRQAQR
Atome Classification :
(20 SA)
.........10...----.....20.--------.----......30....--....40.......--.50.--.......60.-...-....70........--80-----------------.....-...90-----........100-........-110.-......120.......130......--.140.....----..150.......160.-.-----------.....170-....--.....180.......190.....--------------.-.200......-.210......---.220..--.....230.-----....-------------------------..240.......250..---...-..260.....--..270------.......280......--------.290....-.-..300.-----......310...-----------------------....320.......330---........340......-.350........360....-----..---.370......--.380...-.....390.......---400.......-410.-...-------------...420....---------...430--------------.......-.440.-----..-.....450.....-------..-460..-.....470---------....--...480-..-...------..490.-.-----....--..500....-------...510.--...-...520....-----...530....------...540-----........-----------550--.-...-...---.-560..-.....---------570...----....580.---......590...-..-..600---.-.......610-.........620....------------...630.---......640.......650.......660..--------------------.....670.......680----..-----------.....690..-.....700....--..-.710.......720.---......730......--.740.......------.750........760.......770...----....780......------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDVSSSP
N
I
T
F
M
L
Q
----YTEANP
Q
Y
--------V----DYTN
R
E
E
A
V
KI
D
--
E
ELSL
E
T
N
R
Q
M
I
E
--GL
T
E
--
D
E
L
T
R
I
Q
E
AV-PET-QL
N
F
R
E
Y
I
D
Y
M
NRS--YA-----------------
T
E
E
QS-K
E
L
T
A
-----
I
FTQ
E
A
D
Y
L
Q
--
K
L
R
L
I
D
L
K
-
N
K
L
E
-
S
A
Y
QNG
S
L
L
W
Q
G
V
I
SF
D
N
A
F
L
A
EQG--LYDVATGQ
V
----
D
Q
K
A
I
K
A
V
M
R
D
M
M
P
T
L
-
I
-----------
Q
KEGLS---DS
A
F
--
W
W
G
N
I
H
L
NTD
N
I
H
I
H
FG
L
S
E
V
ES--------------N-R
E
K
I
F
YQPRG-
R
M
E
YKGNF
S
Q
---
K
T
I
N
R
F
--
K
S
G
V
Y
H
G
L
L
-----
K
E
E
T
-------------------------
R
S
N
L
L
R
K
E
Q
I
L
A
N
L
K
A
D
---
F
I
T
-
S
I
Y
Q
KDKIT
S
--
S
A
E
K
N
------
F
L
E
Q
A
Y
NHLPLNKKWR--------YGSN
A
R
D
F
-
A
-
V
S
K
F
F
L
-----
D
R
Y
L
D
S
Y
LNNEG-----------------------
S
A
A
Y
Q
E
F
L
K
E
T
R
D
F
L
Q
----
T
Y
E
G
V
YSA
E
K
N
K
I
Y
E
K
L
-
R
KV-D
G
Q
T
I
R
T
L
A
ESKGY
D
-----
L
E
---
H
H
L
A
R
R
V
M
D
L
--
R
E
R
-
L
A
N
-
N
I
L
R
S
F
R
E
AAPQI
Q
D
---
V
Q
L
E
K
N
L
E
S
F
-
S
V
L
N
-
Q
K
K
-------------
I
L
E
QHP
E
A
S
V
---------
V
K
S
Q
K
---------------
A
W
Q
KL
G
Y
-
F
V
K-A-----GE-
Q
P
L
E
I
I
R
P
V
Y
K
S
Y
-------
D
K-HGKGI-GR
P
E
FV
S
D
---------
T
V
Y
D
--
I
S
Q
L
T
E-N
I
-
Q
L
K
------
S
L
T
-
L
K
-
D
-----
L
S
LF--
S
S
N
E
L
K
E
L
V
-------
D
A
A
KLKT--NP
T
-
E
R
E
R
R
ELG
T
Y
-----
R
Y
A
L
K
L
S
I
L
E------S
S
Q
K
E
------
L
Q
V
R
Q
K
L
L
-----------
E
Q
---
V
-
Q
P
L
-ASD---Q-
P
F
L
D
F
-
K
K
Q
L
I
---------
A
Q
E
L
Q
A
----
I
A
L
Q
LTPN---YKLSE
D
D
K
A
L
K
N
-
R
L
-
K
R
Q
-
F
---E-DSVALPVS---KATPG
A
I
QL
P
I
R
Q
L
W
T
------------ELG
L
V
H
H---IQDE
N
I
L
T
L
LKGTS
T
T
K
Q
A
Y
I
E
E
L
Q
T
H
I
S
I
F
--------------------
Q
L
K
Y
Q
INNRN
K
Q
I
S
QLSD----E
A
-----------
T
I
K
E
MRIANA-K
G
F
S
E
L
K
R
L
Y
D
T--LQ-PSDD
G
Q
N
Q
I
S
Q
A
V
S
K
---
Q
L
Q
E
R
K
V
I
K
K
A
Q
L
Q
Q
--
T
Q
R-SGKI
N
T
D
------
F
M
R
-
Q
L
T
A
SLN
R
S
Q
Q
A
S
K
K
A
L
M
E
R
ARSD----
E
R
E
E
Q
E
E
R
R
Q
AQR------------------------------------
49
Fugue
79.37
18%
-3
- C4 -
4XC8
4
?
A:
[42-1113]
---
G
P
A
N
K
V
R
F
V
T
A
----
A
S
L
F
D
G
H
D
--------
A
----
S
I
N
I
M
R
R
I
L
Q
S
Q
GC
E
V
I
H
L
G
H
N
R
S
V
Q
E
--
V
V
T
A
--
A
L
Q
E
D
V
Q
G
I
A
-
I
S
S
Y
Q
G
G
H
V
E
Y
F
K
Y
M
I
D
L
--
L
R
E
H
GGEH
I
Q
V
F
G
G
GGGVI
V
P
D
E
I
-
R
E
L
Q
A
Y
GVA
R
I
Y
S
P
E
D
G
Q
R
M
G
L
A
G
M
I
T
D
M
A
-
Q
R
C
D
I
D
L
T
R
Y
A
P
T
T
L
D
T
V
V
A
G
D
R
R
A
L
A
-
Q
L
--
I
T
A
L
E
N
G
K
A
----
D
P
E
L
V
S
A
L
H
A
Q
A
K
A
A
A
-
V
P
V
L
G
I
T
G
T
GGA
G
K
S
S
L
T
---
D
E
L
I
R
R
F
R
L
D
Q
D
D
A
L
S
I
A
V
I
S
I
D
P
S
R
R
K
S
GGALLGDRIRMNAI
N
-
H
P
N
I
F
M
R
S
L
A
-
T
R
E
A
G
S
E
I
S
Q
A
L
P
D
V
I
A
A
C
--
K
A
A
R
F
D
L
V
I
-----
V
E
T
S
GIGQGDAAIVPHVD
L
S
L
Y
V
M
T
PEFG
A
A
S
Q
L
E
K
I
D
M
L
D
F
--
A
D
---
F
V
A
-
I
N
K
F
D
R
K
G
A
Q
--
D
A
W
R
D
------
V
A
K
Q
V
Q
R
N
---
R
E
Q
W
H
SRAEDMP
V
Y
G
T
Q
A
S
R
F
N
D
-
D
G
V
T
M
L
-----
Y
Q
G
L
V
G
A
L
G
A
R
G
M
S
L
K
PGTLPNLEGRISTGQNVIV
P
P
A
R
S
R
Y
L
A
E
L
A
D
T
V
R
----
A
Y
H
R
R
V
V
A
Q
S
K
L
A
R
E
R
Q
-
Q
L
R
-
A
A
H
D
M
L
Q
G
A
G
H
E
S
A
A
-----
L
E
---
T
L
A
S
E
R
D
V
S
L
G
A
V
E
R
-
K
L
L
-
A
M
W
P
Q
M
Q
Q
A
Y
S
G
D
E
Y
---
V
E
I
R
T
G
L
I
S
T
-
T
L
S
G
-
T
K
I
R
K
V
V
L
P
RFED
E
G
E
I
L
K
W
L
M
R
E
N
V
PGSFPYTAG
V
F
A
F
K
REGEDP
T
R
M
F
A
G
E
G
D
A
F
R
T
N
R
R
-
F
K
L
-
V
-----
S
E
G
M
E
A
K
R
L
S
T
A
F
D
S
V
-------
T
L
-
Y
G
E
D
P
H
E
R
P
D
I
Y
G
K
VGNS
G
V
S
I
A
T
L
E
D
--
M
K
V
L
Y
D
-
G
F
-
D
L
T
NPS
T
S
V
S
M
T
-
I
N
-
G
P
A
P
T
I
L
A
M
F
--
M
N
T
A
I
D
Q
Q
I
-------
D
R
F
R
A
D
N
GR
D
P
T
-
A
D
E
E
A
K
I
R
A
W
V
L
Q
N
V
R
G
T
V
Q
A
D
I
L
K
------
E
D
Q
G
Q
NTCIFS
T
E
F
S
L
K
V
M
-----------
G
D
---
I
-
Q
E
Y
-
F
V
H
---
H
-
Q
V
R
N
F
-
Y
S
V
S
I
SG
Y
H
I
A
E
A
G
A
N
P
I
S
Q
----
L
A
F
T
L
A
N
G
---
F
T
Y
V
E
A
Y
L
A
R
G
M
-
H
I
-
D
-
D
-
F
---
A
-
P
N
L
S
F
F
F
S
N
G
M
D
P
E
Y
S
V
L
G
R
V
A
R
R
I
W
A
V
T
M
R
DKYGANDR
S
Q
K
L
K
Y
H
---
I
Q
T
S
G
--
R
S
L
H
A
Q
E
I
D
F
N
D
I
R
T
T
L
Q
A
L
I
A
I
Y
D
NCN
S
L
H
T
N
A
YDEAITTPT
A
E
S
V
R
R
A
L
A
I
Q
L
I
I
N
R
E
W
G
----
V
A
KCENPNQGS
F
L
I
E
E
L
T
D
L
V
E
E
-
A
V
L
Q
E
F
E
R
I
A
E
R
GG
V
L
-
G
A
M
E
T
G
Y
Q
R
G
K
I
Q
E
E
---
S
L
Y
Y
E
Q
L
K
H
D
G
T
L
P
I
--
I
G
V
-
N
T
F
R
N
P
N
------
G
D
P
-
R
S
S
E
D
E
K
Q
S
Q
L
H
R
L
T
E
F
H
G
A
H
Q
A
D
----
A
E
A
M
L
A
R
L
R
Q
A
V
I
D
NRN
V
F
A
V
L
M
D
A
V
R
V
CS
L
G
Q
I
T
H
A
L
F
E
V
GGQYRRNM
50
Fugue
72.05
20%
17
- C4 -
4QEI
1
SYG_HUMAN
A:
[1-617]
--
I
V
D
R
A
K
M
G
D
T
L
K
R
R
FF
Y
D
Q
A
F
A
I
Y
--------
G
GVSG
L
Y
D
F
G
P
V
G
C
A
L
K
--
N
N
I
I
Q
T
W
R
Q
H
F
I
Q
EE
Q
I
L
E
--
I
D
C
T
M
---
L
T
-
P
E
P
-
V
L
K
T
S
G
H
V
D
K
F
A
D
F
--
M
V
-----------------
K
D
V
K
N
-
G
E
----------
R
F
R
A
D
H
L
L
--
K
A
H
L
Q
K
L
Q
-
Q
E
L
A
-
D
L
F
V
N
F
N
L
M
F
K
T
F
I
----------
G
--
P
G
G
N
M
P
G
Y
L
----
R
P
E
T
A
Q
G
I
F
L
N
F
K
R
L
L
-
E
-----------
F
N
Q
G
-----------------------
K
L
P
F
A
A
A
Q
I
G
N
--------------
S
F
R
N
E
I
--
S
P
R
S
-
G
L
I
R
V
R
E
F
T
M
---
A
E
I
E
H
F
V
D
P
S
E
K
D
H
P
K
F
-----
Q
N
V
-----------------------------------------
A
D
---
L
H
L
-
Y
L
Y
S
A
K
A
Q
V
S
GQ
S
A
R
K
M
------
R
L
G
D
A
V
E
Q
G
V
I
N
N
--------------------
T
-
V
L
G
Y
F
I
-----
G
R
-
I
Y
L
Y
L
T
K
V
G
-----------------------------
I
S
P
D
K
L
R
F
R
Q
----
H
M
E
D
C
W
D
A
E
S
K
T
S
Y
--------
G
W
I
E
I
V
G
C
A
D
R
S
C
Y
D
-----
L
S
---
C
H
A
R
A
T
K
V
P
L
--
V
---------------------------
A
E
K
P
L
K
E
P
-
K
T
V
N
-
V
V
Q
-------------
F
E
P
S
K
G
A
I
G
K
---------
A
Y
K
K
D
---------------
A
K
L
V
M
E
Y
-
L
A
I
-
C
---------------------------------------------------------
D
--
E
C
Y
I
T
E
-
M
E
-
M
L
L
---------------------------
N
E
K
G
E
F
T
-------
I
E
T
Q
L
T
K
--
D
M
I
-
N
V
K
R
F
Q
K
T
L
Y
-----
V
E
E
V
V
P
N
V
I
E
------
P
S
F
G
L
------
G
R
I
M
Y
T
V
F
-----------
E
H
T
F
H
V
-
R
E
G
-
D
E
Q
---
R
-
T
F
F
S
F
-
P
A
V
V
A
---------
P
--
F
K
C
----
S
V
L
P
L
S
Q
N
---
Q
E
F
M
P
F
V
K
E
L
S
E
-
A
L
-
T
R
H
------------------------------------------------
G
V
S
H
K
---
V
D
D
S
S
------
G
S
I
G
R
R
Y
A
R
T
D
E
I
G
V
A
F
G
V
---------------------
T
I
D
F
D
T
V
N
K
T
P
H
T
A
T
L
R
D
----
R
D
-----------
S
M
R
Q
I
R
A
E
-----
I
S
E
L
P
S
I
V
Q
D
--
L
A
-
N
G
N
----------------------------------------------------------
I
T
W
A
D
V
E
A
R
Y
P
L
F
E
G
Q
E
T
G
----
K
K
-----------------------------------------------
55
Fugue
61.49
14%
3
- C1 -
3UGM
-
PTHX1_XANOP
A:
[169-1048]
-----
K
P
K
V
R
E
L
V
A
----
H
I
V
A
L
S
Q
H
PAALGTVA
V
----
T
Y
Q
H
I
I
T
A
L
A
T
H
--
E
D
I
V
G
V
G
K
Q
W
S
G
A
--
R
A
L
E
--
A
L
L
T
D
A
G
E
L
R
G
P
P
L
-
Q
L
D
T
G
Q
L
V
K
I
A
K
R
G
G
V
T
A
-----------------
M
E
A
V
H
-
A
S
R
N
A
-----
L
T
P
L
N
L
T
P
A
Q
--
V
V
A
I
A
----------
S
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
--
L
T
P
A
Q
V
V
A
I
A
SHD
G
G
K
Q
A
L
E
T
M
Q
R
L
L
P
V
L
-
C
-----------
Q
A
H
G
L
P
---
P
D
Q
V
--
V
A
I
A
-----
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
--------------
L
-
L
P
V
L
C
Q
A
H
G
L
-
T
P
D
Q
V
V
A
I
A
S
---
H
G
G
G
K
Q
--
A
L
E
T
V
Q
R
L
L
-----
P
V
L
C
-------------------------
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
-
E
T
V
Q
R
L
L
P
V
L
--
C
Q
A
H
G
------
L
T
P
D
Q
V
V
A
I
A
S
N
G
G
G
K
--------
Q
A
L
E
T
V
Q
R
-
L
-
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
S
N
G
G
-----------------------
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGL
T
P
D
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
-
L
E
T
-
V
Q
R
L
L
P
V
L
C
Q
T
H
G
L
T
-------------
P
A
Q
V
V
A
I
--
A
S
H
D
G
G
K
-
Q
A
L
E
T
V
Q
Q
L
L
P
V
L
C
Q
AHG
L
T
P
D
Q
V
V
A
I
A
-
S
N
I
G
-
G
K
Q
-------------
A
L
A
T
V
Q
R
L
L
P
---------
V
L
C
Q
A
---------------
H
G
L
T
P
D
Q
-
V
V
A
-
I
A
S
N
GG
G
K
-
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
-
Q
V
V
A
I
-
A
S
N
G
G
G
K
Q
---------
A
L
E
T
--
V
Q
R
L
L
P
-
V
L
-
C
Q
A
H-----
G
L
T
-
Q
V
-
Q
-----
V
V
A
I
--
A
S
N
I
G
G
K
Q
A
-------
L
E
T
V
Q
R
L
--
L
P
V
-
L
C
Q
A
H
G
L
-
T
P
-----
A
Q
V
V
A
I
A
S
H
D
------
G
G
K
Q
A
------
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
---
V
-
V
A
I
-
A
S
N
GG
G
K
-
Q
A
L
E
T
-
V
Q
R
L
L
---------
P
G
L
T
Q
E
----
Q
V
V
A
I
A
S
N
NGG
K
Q
A
L
E
T
V
Q
R
L
L
P
-
V
L
-
C
Q
A
-
H
GLT
P
-
D
Q
V
V
A
I
A
S
---
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
------------
V
L
C
Q
A
H
G
---
L
T
P
A
Q
V
V
A
I
A
S
N
I
G
--
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
--------------------
C
Q
D
H
G
L
T
--
L
A
Q
V
V
A
I
A
S
NIG
G
K
Q
-----------
A
L
E
T
V
Q
R
L
L
P
-
V
L
C
Q
G
L
T
Q
D
Q
V
V
--
A
I
-
A
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
LLP
V
L
C
Q
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
-
G
G
K
Q
A
L
E
------
T
V
Q
-
R
L
L
P
V
L
C
Q
D
H
G
L
T
L
D
Q
V
V
A
I
A
S
N
G
----
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
DHGLTPDQVVAIASNSG---------------
51
Fugue
56.68
17%
-11
- C4 -
4C0E
-
?
A:
[9-528]
------------------------------------------------------------------------------
L
E
A
A
H
L
-
L
E
Q
M
E
Y
V
F
D
E
W
I
H
L
C
N
N
P
--
H
A
-----------------
T
E
R
A
A
M
I
----------------
F
V
H
--
Q
L
H
S
V
Q
L
V
T
N
R
D
E
-
F
L
L
F
L
R
H
A
L
D
K
S
V
E
R
F
E
Q
G
I
H
S
G
--------
A
S
I
A
E
----
S
F
Q
A
V
E
A
L
V
K
L
I
I
I
F
V
-
K
-----------
S
H
S
A
A
V
A
F
M
D
S
I
L
--
A
L
G
V
L
V
A
N
S
H
H
V
K
----------------------------------------
R
G
E
N
F
N
Q
---
R
V
F
Y
R
F
--
F
A
L
L
L
H
E
V
G
-----
L
L
A
G
-------------------------
H
F
S
K
S
H
Y
E
Q
I
I
L
N
F
A
A
R
---
L
F
D
M
R
P
-----------------------------------------------
N
L
L
P
G
F
-
A
-
C
A
W
A
G
L
V
S
H--
R
A
F
L
P
V
I
L
G
L
P
D
-----------------------
E
K
G
W
A
P
F
T
K
L
L
E
Q
F
L
G
----
C
V
G
E
L
V
K
T
F
T
V
S
S
L
G
K
E
M
Y
H
A
-
A
L
K
I
L
I
V
L
Q
H
D
F
P
I
Y
-----
L
D
K
F
R
V
Q
L
C
Q
S
L
P
L
H
--
A
T
Q
-
L
V
N
-
L
I
L
A
A
I
P
P
N
C
N
S
L
A
D
----
P
F
Q
A
G
L
K
V
D
-
K
I
P
D
M
K
E
R
-------------
P
P
T
A
F
D
S
A
G
L
---------
L
R
E
A
G
---------------
L
L
D
I
L
E
R
M
L
Q
N
G
P
-----
S
E
-
D
G
V
A
Q
I
N
H
A
I
N
K
S
-------
T
S
-
F
G
Y
----
V
P
L
G
V
N
R
---------
R
L
I
D
A
V
V
A
R
F
A
E
-
F
A
-
I
N
R
------
A
S
S
-
R
S
-
D
-----
S
A
I
F
VA
G
A
N
D
I
K
T
L
Q
M
L
V
T
E
VS
P
E
A
R
Y
Y
L
--
V
S
S
M
V
N
E
L
R
Y
P
N
A
Y
-----
T
N
Y
F
S
Q
A
L
L
D
I
F
G
HDM
S
D
P
E
E
------
N
L
V
R
E
Q
I
V
-----------
R
V
---
L
-
L
E
R
-
V
L
G
---
Y
-
W
P
Q
P
W
-
G
L
I
I
T
---------
I
L
E
L
L
K
NDKY
L
F
F
E
L
-
P
F
---
I
K
A
T
P
E
V
A
E
R
F
T
-
A
L
-
A
R
S
-
A
---
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
50.38
13%
28
* C3 *
1D8C
8
MASZ_ECOLI
A:
[3-722]
-
Q
T
I
T
Q
S
R
L
R
I
D
-----------
A
N
F
--------
K
----
R
F
V
D
E
E
V
L
P
G
T
G
--
L
-----
D
A
A
A
F
W
R
--
N
F
D
E
I
V
H
D
L
A
P
E
N
R
Q
L
-
L
A
E
-
R
D
R
I
Q
A
A
L
D
E
W
H
R
S
--
N
P
-----------------
G
P
V
K
D
-
K
A
A
Y
K
-----
S
F
L
R
E
L
G
Y
L
V
--
P
-----------------------------------
Q
P
E
--
R
V
T
V
E
T
T
G
I
----
D
S
E
I
T
S
Q
A
G
P
Q
L
V
V
P
A
M
N
-----------
A
R
Y
A
L
N
---
A
A
N
A
--
R
W
G
S
L
Y
D
A
L
Y
G
-----------------------------
S
D
I
I
P
Q
E
G
A
M
V
S
G
Y
D
P
Q
R
G
E
---
Q
V
I
A
W
V
--
R
R
F
L
D
E
S
L
P
LENGS
Y
Q
D
V
-------------------------
V
A
F
K
V
V
D
K
Q
L
R
I
Q
L
K
N
G
---
K
E
T
-
T
L
R
T
P
A
Q
F
V
G
--
Y
R
G
D
A
AAPT
C
I
L
L
K
N
N
G
L
H
I
E
L
Q
I
D
A
N
--------
G
R
I
G
K
D
D
P
-
A
H
I
N
D
V
I
V
-----
E
A
A
I
S
T
I
L
D
C
E
D
-----------------------
S
V
A
--------------------
A
V
D
A
E
D
K
I
L
L
Y
R
N
L
-
L
G
L
M
Q
G
T
L
Q
R
K
L
N
D
D
R
H
Y
T
A
ADG
S
E
I
---
S
L
H
G
R
S
L
L
F
I
--
R
N
V
-
G
H
L
M
T
I
P
V
I
W
D
S
E
G
N
E
I
P
-------
E
G
I
L
D
G
V
M
T
G
A
I
-
A
L
Y
-------------
D
L
K
V
Q
-----------------
K
N
---------------
S
R
T
G
S
V
Y
-
I
V
K
-
P
-----------------------------
K
M
H
G
------
P
Q
E
V
A
F
---------
A
N
K
L
--
F
T
R
I
E
T
M
L
G
M
A
P
N
------
T
L
K
M
G
I
M
D
-----
E
E
R
R
--
T
S
L
N
L
R
S
C
I
-------
A
Q
A
R
N
R
V
----------------------
A
F
I
N
T
G
F
L
D
------
R
T
G
D
E
-------------------------------
M
H
S
V
M
E
A
G
---
P
M
L
R
K
N
Q
M
K
S
T
P
W
---------
I
K
A
Y
E
R
----
N
N
V
L
S
G
L
F
---
C
G
L
R
G
K
A
Q
I
G
K
G
M
W
A
M
P
D
L
M
A
---
D
M
Y
S
Q
K
G
D
Q
L
---
R
A
G
A
N
T
A
W
V
P
S
P
T
A
A
T
------------
L
H
A
L
H
Y
H
Q
TN
V
Q
S
V
Q
A
N
I
A
Q
T
E
F
N
A
E
F
E
P
L
L
D
D
L
L
T
I
P
V
A
E
--------------------
N
A
N
W
S
A
Q
E
I
Q
Q
E
L
D
N
N
V
Q
----
G
I
-----------
L
G
Y
V
V
R
W
V
E
Q
G
I
G
C
S
K
V
P
D
I
H
N
V
--
A
L
M
E
D
R
A
T
L
R
I
S
S
Q
H
I
A
N
---
W
L
R
H
G
I
L
T
K
E
Q
V
Q
A
S
--
L
E
N
M
A
K
V
V
D
Q
Q
N
AGDPA
Y
R
P
M
A
G
N
F
A
N
S
C
A
F
K
A
A
S
D
L
I
F
L
G
V
K
Q
P
NGYT
E
P
L
L
H
A
W
R
L
R
E
K
E
S-----------------------------------
29
PsiBlast_CBE
44.68
32%
87
- C2 -
1URN
5
SNRPA_HUMAN
B:
[1-78]
----------------------------------------------------------------------------------
A
V
-
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
44.57
33%
85
- C2 -
1OIA
-
SNRPA_HUMAN
A:
[3-79]
-----------------------------------------------------------------------------------
V
-
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
Y
A
-----
I
F
S
Q
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
44.50
32%
90
- C2 -
1URN
3
SNRPA_HUMAN
A:
[1-78]
----------------------------------------------------------------------------------
A
V
-
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
44.38
32%
86
- C2 -
1M5V
7
SNRPA_HUMAN
F:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
44.21
32%
88
- C2 -
1M5V
1
SNRPA_HUMAN
C:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
44.10
32%
82
- C2 -
3UD4
1
SNRPA_HUMAN
P:
[7-79]
-----------------------------------------------------------------------------------------
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
44.03
32%
92
- C2 -
1VBZ
-
SNRPA_HUMAN
A:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
44.00
32%
84
- C2 -
1URN
4
SNRPA_HUMAN
C:
[1-78]
----------------------------------------------------------------------------------
A
V
-
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
43.93
32%
80
- C2 -
3UCZ
1
SNRPA_HUMAN
P:
[7-79]
-----------------------------------------------------------------------------------------
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
43.78
32%
93
- C2 -
1VBX
-
SNRPA_HUMAN
A:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
43.78
32%
91
- C2 -
1DRZ
2
SNRPA_HUMAN
A:
[3-78]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
43.76
32%
91
- C2 -
1VC0
-
SNRPA_HUMAN
A:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
43.76
33%
58
- C2 -
1FHT
-
SNRPA_HUMAN
A:
[1-78]
----------------------------------------------------------------------------------
A
V
-
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
Y
A
-----
I
F
S
Q
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
G
T
F
-
V
-----------
E
R
D
R
K
R
---
E
K
R
K
--
P
K
S
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
43.69
32%
93
- C2 -
1SJ4
-
SNRPA_HUMAN
P:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
43.49
32%
92
- C2 -
1SJF
1
SNRPA_HUMAN
A:
[4-79]
-------------------------------------------------------------------------------------
P
E
T
-
R
P
N
H
T
I
Y
I
N
N
L
N
E
K
--
I
K
-----------------
K
D
E
L
K
-
K
S
L
H
A
-----
I
F
S
R
F
G
Q
I
L
D
--
I
L
V
S
R
S
L
K
-
M
R
G
Q
-
A
F
-----
V
I
F
K
E
V
S
S
A
T
N
A
L
R
S
M
Q
G
FP
F
Y
D
K
P
M
R
I
Q
----
Y
A
K
T
D
S
D
I
I
A
K
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------