@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0451: (2015-12-01 )
MDKHHSKKAILKLTLITTSILLMHSNQVNAEEQELKNQEQSPVIANVAQQPSPSVTTNIVEKTSVTAASASNTAKEMGDTSVKNDKTEDELLEELSKNLDTSNLGADLEEEYPSKPETTNNKESNVVTNASTAIAQKVPSAYEEVKPESKSSLAVFDTSKITKLQAITQRGKGNVVAIIDTGFDINHDIFRLDSPKDDKHSFKTKAEFEELKAKHNITYGKWVNDKIVFAHNYANNTETVADIAAAMKDGYGSEAKNISHGTHVAGIFVGNSKRPAINGLLLEGAAPNAQVLLMRIPDKIDSDKFGEAYAKAITDAVNLGAKTINMSLGKTADSLIALNDKVKLALKLASEKGVAVVVAAGNEGAFGMDYSKPLSTNPDYGTVNSPAISEDTLSVASYESLKTISEVVETTIEGKLVKLPIVTSKPFDKGKAYDVVYANYGAKKDFEGKDFKGKIALIERGGGLDFMTKITHATNAGVVGIVIFNDQEKRGNFLIPYRELPVGVISKVDGERIKNTSSQLTFNQSFEVVDSQGGNRMLEQSSWGVTAEGAIKPDVTASGFEIYSSTYNNQYQTMSGTSMASPHVAGLMTMLQSHLAEKYKGMNLDSKKLLELSKNILMSSATALYSEEDKAFYSPRQQGAGVVDAEKAIQAQYYVTGNDGKAKINLKRVGDKFDITVTIHKLVEGVKELYYQANVATEQVNKGKFALKPQALLDTNWQKVILRDKETQVRFTIDASQFSQKLKEQMANGYFLEGFVRFKEAKDSNQELMSIPFVGFNGDFANLQALETPIYKTLSKGSFYYKPNDTTHKDQLEYNESAPFESNNYTALLTQSASWGYVDYVKNGGELELAPESPKRIILGTFENKVEDKTIHLLERDAANNPYFAISPNKDGNRDEITPQATFLRNVKDISAQVLDQNGNVIWQSKVLPSYRKNFHNNPKQSDGHYRMDAFQWSGLDKDGKVVADGFYTYRLRYTPVAEGANSQESDFKVQVSTKSPNLPLLAQFDETNRTLSLAMPKESSYVPTYRLQLVLSHVVKDEEYGDETSYHYFHIDQEGKVTLPKTVKIGESEVAVDPKALTLVVEDKAGNFATVKLSDLLNKAVVSEKENAIVISNSFKYFDNLKKESMFISKEGKVVNKNLEEITLVKPQTTVTTQSLSKEITKSGNEKVLTSTNNNSSRVAKIISPKHNGDSVNHTLPSTSDRATNGLFVGTLALLSSLLLYLKPKKTKNNSK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.-...-.-..170.......180.......190.......200......-.210.....-..220.......230.......240.......250.......260.......270......----..280-........--.290.......300---..-.......310.-....--------------------..-320---.........330....--.----..340......--.-----350.......360.......370-----........380.......--390.......400.......410.------...-..--.-.420-------------.......-..------430....-------------.-------..-----440..--..--....450.......460.----......470.......480.......490..--.---.-.-..500.......510..-.-------..-----..-520.......530.......540..--....--.550.......560..--------------...----------------------------------.------------------.--------------570.......580.......590......-.---------600.......610.......620.....-------.-------.--------------------------630.......640......--------.650.....-----------------------------------.--.660......-..---------------------------670---.---........680.......690...-----....700.......710.......720...-.-....730.......740.......750.......760.......770.......780.......790.......800.......810......-.820--.......830.......840....----.---..850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010..-....1020......1030......1040......1050......1060.....-.1070.......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDKHHSK
K
A
I
L
K
L
T
L
I
T
T
S
I
L
L
M
HSNQVN
A
E
E
Q
E
L
KNQEQS
P
V
I
A
N
VAQQPSPS
V
T
T
N
I
V
EKT
S
V
TAASASN
T
A
K
EMGDTSVKNDK
T
E
D
E
L
L
E
E
L
S
KNLDTSNLGA
D
L
E
E
EYPSKPETTNNKES
N
V
VTN
A
S
T
A
I
A
Q
KV
P
S
A
Y
E
EVKPESKS
S
L
A
V
FDT
S
K
I
T
K
-
L
Q
A
-
I
-
T
QRGKG
N
V
V
A
I
I
DTGFDINHD
I
F
RLDSPKDDKHSFK
T
K
A
E
F
-
E
E
L
K
A
KHNI-TYGKWVN
D
K
I
V
F
A
HNYANN
T
E
T
V
A
D
I
A
A
A
M
KDGYGSEAKNISHG
T
H
V
A
G
I
F
VGN-SKRPAI----N
G
L
---
L
LEGAAPN--
A
Q
V
L
L
M
RIPDKI-----DS-
D
K
F
G
E
A
Y
A
K
A
I
-
T
D
A
V
--------------------NL-G-----
A
K
T
I
N
MSLGKTA
D
S
L
I
--A----LND
K
V
K
L
A
L
K
L--A-----SEK
G
V
A
V
V
V
A
AGNEGAFGMDYS------KPLSTNPDYGTVNSPAIS--EDTL
S
V
A
S
Y
E
S
L
K
T
I
S
E
V
V
E
T
-TI------EG
K
-
L
V
--
K
-
L
P
---------------
I
VTSKPF-DK------GK
A
Y
D
V
V
-------------
Y
-------AN-----Y-GAK--KD--FEGKDFK
G
K
I
A
L
I
ERGGG----
L
D
F
M
T
K
I
THATNA
G
V
V
G
I
V
I
FNDQEKRG
N
F
L
--
I
---P-Y-REL
P
V
G
V
I
SKVD
G
E
R
IK-N-------TS-----S
Q
-
L
T
FNQ
S
F
E
V
VDSQGGNR
M
L
EQSSWG--VTAE--GAIKPDVTAS
G
F
E
I
Y
S
--------------STY----------------------------------N------------------N--------------
Q
Y
Q
TMSGTSMAS
P
H
V
A
G
L
M
T
M
L
Q
S
H
L
A
E
K
-Y---------KGMNL
D
S
K
K
L
L
E
L
S
K
N
I
L
M
S
S
A
T
A
LYSE-------E-------D--------------------------
K
A
FYSPRQQGAGVV
D
A
E
K
A
--------
I
Q
A
Q
Y
Y
V
TG-----------------------------------N--D
G
-
K
A
K
I
N
L
K
-RV---------------------------G-----D---KF
D
I
T
V
T
I
H
K
L
V
E
G
V
K
E
L
Y
Y
QANV-----A
T
E
QVNKG
K
F
ALK
P
Q
A
L
LDTNW
Q
K
V
-
I
L
RD-K-E
T
Q
V
R
F
T
I
D
A
S
Q
F
S
Q
K
L
K
E
Q
M
ANG
Y
F
L
E
G
F
V
R
F
K
EAKDSNQ
E
L
M
SI
P
F
VGFNGDFA
N
L
Q
A
L
E
T
P
I
Y
K
TLSKG
S
F
Y
YKPNDTT
H
K
D
Q
LEYNESA-PFES--N
N
Y
T
A
L
L
TQSASWG
Y
V
D
YVKNGG
E
----
L
---
E
LAPESP
K
R
I
I
L
GTFENKVED
K
T
I
H
L
L
ERDAANN
P
Y
F
A
ISPNKDGNRDEIT
P
Q
A
T
F
L
R
N
V
K
D
I
S
A
Q
V
L
DQNG
N
V
I
W
QSKV
L
P
S
Y
R
K
NFHNNPKQSDGHY
R
M
D
A
F
Q
WSGLDKDG
K
V
V
A
D
G
F
Y
T
Y
R
L
R
Y
T
PVAEGANSQES
D
F
K
V
Q
V
STKSPNL
P
L
L
A
Q
FDETN
R
T
L
S
L
A-MPKESSYV
P
T
Y
R
L
Q
L
V
L
S
H
V
VKDEEYGDET
S
Y
H
Y
F
H
IDQEG
K
V
TL
P
K
T
V
K
IGE-SE-VAVDP
K
A
L
T
L
V
V
EDKAG
N
F
A
T
V
K
L
S
D
L
L
N
K
A
V
VSEKE
N
A
I
V
ISNS
F
K
Y
F
D
NL
K
K
E
S
M
F
ISKEG
K
V
VNKNLE
E
I
T
L
VKPQTTV
T
T
Q
S
L
S
K
E
I
T
KSGN
E
K
V
L
T
STNN
N
S
S
R
V
A
K
I
ISPKHNGDSVNHTLPSTSDRATNG
L
F
V
G
T
L
A
L
L
S
S
L
L
L
Y
LKPKKTKNNSK
1
PsiBlast_PDB
96.50
43%
-52
- C2 -
3EIF
11
C5AP_STRPY
A:
[11-932]
------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
S
Q
V
K
T
-
L
Q
E
-
K
-
A
S
K
G
A
G
T
V
V
A
V
I
D
A
G
F
D
K
N
H
E
A
W
R
L
T
D
K
T
--
K
A
R
Y
Q
S
K
E
D
L
-
E
K
A
K
K
E
H
G
I
-
T
Y
G
E
W
V
N
D
K
V
A
Y
Y
H
D
Y
S
K
D
G
K
T
A
V
D
Q
---------------
E
H
G
T
H
V
S
G
I
L
S
G
N
-
A
P
S
E
T
K
----
E
P
Y
---
R
L
E
G
A
M
P
E
--
A
Q
L
L
L
M
R
V
E
I
V
N
-----
G
L
-
A
D
Y
A
R
N
Y
A
Q
A
I
-
R
D
A
V
--------------------
N
L
-
G
-----
A
K
V
I
N
M
S
F
G
N
A
A
L
A
Y
A
--
N
----
L
P
D
E
T
K
K
A
F
D
Y
--
A
-----
K
S
K
G
V
S
I
V
T
S
A
G
N
D
S
S
F
G
G
K
T
R
------
L
P
L
A
D
H
P
D
Y
G
V
V
G
T
P
A
A
A
--
D
S
T
L
T
V
A
S
Y
S
P
D
K
Q
L
T
E
T
A
T
V
-
K
T
------
D
D
H
-
Q
A
--
K
E
M
P
---------------
V
L
S
T
N
R
F
-
E
P
------
N
K
A
Y
D
Y
A
-------------
Y
-------
A
N
-----
R
-
G
M
K
--
E
D
---
D
F
K
D
V
K
G
K
I
A
L
I
E
R
G
D
-----
I
D
F
K
D
K
I
A
N
A
K
K
A
G
A
V
G
V
L
I
Y
D
N
Q
D
K
G
F
P
I
E
--
L
---
P
N
V
-
D
Q
M
P
A
A
F
I
S
R
K
D
G
L
L
L
K
-
D
-------
N
S
-----
K
K
T
I
T
F
N
A
T
P
K
V
L
P
T
A
S
D
T
K
L
S
R
F
S
S
W
G
--
L
T
A
D
--
G
N
I
K
P
D
I
A
A
P
G
Q
D
I
L
S
--------------
S
V
A
----------------------------------
N
------------------
N
--------------
K
Y
A
K
L
S
G
T
S
M
S
A
P
L
V
A
G
I
M
G
L
L
Q
K
Q
Y
E
T
Q
-
Y
---------
P
D
M
T
P
S
E
R
--
L
D
L
A
K
K
V
L
M
S
S
A
T
A
L
Y
D
E
-------
D
-------
E
--------------------------
K
A
Y
F
S
P
R
Q
Q
G
A
G
A
V
D
A
K
K
A
--------
S
A
A
T
M
Y
V
T
D
-----------------------------------
K
--
D
N
T
S
S
K
V
H
L
N
-
N
V
---------------------------
S
-----
D
---
K
F
E
V
T
V
T
V
H
N
K
S
D
K
P
Q
E
L
Y
Y
Q
A
T
V
-----
Q
T
D
K
V
D
G
K
H
F
A
L
A
P
K
A
L
Y
E
T
S
W
Q
K
I
T
I
P
A
N
-
S
-
S
K
Q
V
T
V
P
I
D
A
S
R
F
S
K
D
L
L
A
Q
M
K
N
G
Y
F
L
E
G
F
V
R
F
K
Q
-
D
P
K
K
E
E
L
M
S
I
P
Y
I
G
F
R
G
D
F
G
N
L
S
A
L
E
K
P
I
Y
D
S
K
D
G
S
S
Y
Y
H
E
A
N
-
S
D
A
K
D
Q
L
D
-
G
D
G
L
-
Q
F
Y
A
LK
N
N
F
T
A
L
T
T
E
S
N
P
W
T
I
I
K
A
V
K
E
G
V
E
NIED
I
---
E
-
S
S
E
I
T
E
T
I
F
A
G
T
F
A
-
K
Q
D
D
D
S
H
Y
Y
I
H
R
H
A
N
G
K
P
Y
A
A
I
S
P
N
G
D
G
N
R
D
Y
V
Q
F
Q
G
T
F
L
R
N
A
K
N
L
V
A
E
V
L
D
K
E
G
N
V
V
W
T
S
E
V
T
E
Q
V
V
K
N
Y
N
N
D
L
A
S
T
L
G
S
T
R
F
E
K
T
R
W
D
G
K
D
K
D
G
K
V
V
V
N
G
T
Y
T
Y
R
V
R
Y
T
P
I
S
S
G
A
K
E
Q
H
T
D
F
D
V
I
V
D
N
T
T
P
E
V
A
T
S
A
T
F
S
T
E
D
R
R
L
T
L
A
S
K
P
K
T
S
Q
--
P
I
Y
R
E
R
I
A
Y
T
Y
M
--
D
E
---
D
L
P
T
T
E
Y
I
S
P
N
E
D
G
T
F
T
L
P
E
E
A
E
T
M
E
G
G
T
-
V
P
L
K
M
S
D
F
T
Y
V
V
E
D
M
A
G
N
I
T
Y
T
P
V
T
K
L
L
E
G
H
S
-----------------------------------------------------------------------------------------------------------------------------------
133
HHSearch
93.21
44%
-56
- C2 -
1XF1
6
C5AP_STRPY
A:
[1-926]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
P
S
Q
V
K
T
-
L
Q
E
-
K
-
A
G
K
G
A
G
T
V
V
A
V
I
D
A
G
F
D
K
N
H
E
A
W
R
L
T
D
K
T
K
--
A
R
Y
Q
S
K
E
D
L
-
E
K
A
K
K
E
H
G
I
-
T
Y
G
E
W
V
N
D
K
V
A
Y
Y
H
D
Y
S
K
D
G
K
T
---------------
A
V
D
Q
E
H
G
T
H
V
S
G
I
L
S
G
N
-
A
P
S
E
T
K
----
E
P
Y
---
R
L
E
G
A
M
P
E
--
A
Q
L
L
L
M
R
V
E
I
V
N
-----
G
L
-
A
D
Y
A
R
N
Y
A
Q
A
I
-
R
D
A
I
--------------------
N
L
-
G
-----
A
K
V
I
N
M
S
F
G
N
A
A
L
A
Y
A
--
N
----
L
P
D
E
T
K
K
A
F
D
Y
--
A
-----
K
S
K
G
V
S
I
V
T
S
A
G
N
D
S
S
F
G
G
K
T
R
------
L
P
L
A
D
H
P
D
Y
G
V
V
G
T
P
A
A
A
--
D
S
T
L
T
V
A
S
Y
S
P
D
K
Q
L
T
E
T
V
R
V
-
K
T
------
A
D
Q
Q
D
K
--
E
-
M
P
---------------
V
L
S
T
N
R
F
-
E
P
------
N
K
A
Y
D
Y
A
-------------
Y
-------
A
N
-----
R
-
G
T
K
--
E
D
--
D
-
F
K
D
V
K
G
K
I
A
L
I
E
R
-
G
D
----
I
D
F
K
D
K
I
A
K
A
K
K
A
G
A
V
G
V
L
I
Y
D
N
Q
D
K
G
F
P
I
E
--
L
---
P
-
N
V
D
Q
M
P
A
A
F
I
S
R
K
D
G
L
L
L
K
-
D
N------
P
Q
-----
K
T
-
I
T
F
N
A
T
P
K
V
L
P
T
A
S
G
T
K
L
S
R
F
S
S
W
G
--
L
T
A
D
--
G
N
I
K
P
D
I
A
A
P
G
Q
D
I
L
S
--------------
S
V
A
----------------------------------
N
------------------
N
--------------
K
Y
A
K
L
S
G
T
S
M
S
A
P
L
V
A
G
I
M
G
L
L
Q
K
Q
Y
E
T
Q
-
Y
---------
P
D
--
M
T
P
S
E
R
L
D
L
A
K
K
V
L
M
S
S
A
T
A
L
Y
D
E
-------
D
-------
E
--------------------------
K
A
Y
F
S
P
R
Q
Q
G
A
G
A
V
D
A
K
K
A
--------
S
A
A
T
M
Y
V
T
D
-----------------------------------
K
D-
N
T
-
S
S
K
V
H
L
N
-
N
V
---------------------------
S
-----
D
---
K
F
E
V
T
V
N
V
H
N
K
S
D
K
P
Q
E
L
Y
Y
Q
A
T
V
-----
Q
T
D
K
V
D
G
K
H
F
A
L
A
P
K
V
L
Y
E
T
S
W
Q
K
I
-
T
I
P
A
-
N
S
S
K
Q
V
T
V
P
I
D
A
S
R
F
S
K
D
L
L
A
Q
M
K
N
G
Y
F
L
E
G
F
V
R
F
K
Q
D
P
-
T
K
E
E
L
M
S
I
P
Y
I
G
F
R
G
D
F
G
N
L
S
A
L
E
K
P
I
Y
D
S
K
D
G
S
S
Y
Y
H
E
A
N
S
D
-
A
K
D
Q
L
D
G
D
G
L
Q
F
Y
A
L
K
--
N
N
F
T
A
L
T
T
E
S
N
P
W
T
I
I
K
A
V
K
E
G
V
E
----
N
IED
I
E
S
S
E
I
T
E
T
I
F
A
G
T
F
A
K
Q
D
-
D
D
S
H
Y
Y
I
H
R
H
A
N
G
K
P
Y
A
A
I
S
P
N
G
D
G
N
R
D
Y
V
Q
F
Q
G
T
F
L
R
N
A
K
N
L
V
A
E
V
L
D
K
E
G
N
V
V
W
T
S
E
V
T
E
Q
V
V
K
N
Y
N
N
D
L
A
S
T
L
G
S
T
R
F
E
K
T
R
W
D
G
K
D
K
D
G
K
V
V
A
N
G
T
Y
T
Y
R
V
R
Y
T
P
I
S
S
G
A
K
E
Q
H
T
D
F
D
V
I
V
D
N
T
T
P
E
V
A
T
S
A
T
F
S
T
E
D
R
R
L
T
L
A
-
S
K
P
K
-
T
S
Q
P
V
Y
R
E
R
I
A
Y
T
Y
M
D
E
D
-
L
P
----
T
T
E
Y
I
S
P
N
E
D
G
T
F
T
L
P
E
E
A
E
T
M
E
-
G
A
T
V
P
L
K
M
S
D
F
T
Y
V
V
E
D
M
A
G
N
I
T
Y
T
P
V
T
K
L
L
E
G
H
------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
92.42
42%
-53
- C2 -
1XF1
6
C5AP_STRPY
A:
[2-923]
------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
S
Q
V
K
T
-
L
Q
E
-
K
-
A
G
K
G
A
G
T
V
V
A
V
I
D
A
G
F
D
K
N
H
E
A
W
R
L
T
D
K
T
--
K
A
R
Y
Q
S
K
E
D
L
-
E
K
A
K
K
E
H
G
I
-
T
Y
G
E
W
V
N
D
K
V
A
Y
Y
H
D
Y
S
K
D
G
K
T
A
V
D
Q
---------------
E
H
G
T
H
V
S
G
I
L
S
G
N
-
A
P
S
E
T
K
----
E
P
Y
---
R
L
E
G
A
M
P
E
--
A
Q
L
L
L
M
R
V
E
I
V
N
-----
G
L
-
A
D
Y
A
R
N
Y
A
Q
A
I
-
R
D
A
I
--------------------
N
L
-
G
-----
A
K
V
I
N
M
S
F
G
N
A
A
L
A
Y
A
--
N
----
L
P
D
E
T
K
K
A
F
D
Y
--
A
-----
K
S
K
G
V
S
I
V
T
S
A
G
N
D
S
S
F
G
G
K
T
R
------
L
P
L
A
D
H
P
D
Y
G
V
V
G
T
P
A
A
A
--
D
S
T
L
T
V
A
S
Y
S
P
D
K
Q
L
T
E
T
V
R
V
K
T
A
------
D
Q
Q
-
D
K
--
E
-
M
P
---------------
V
L
S
T
N
R
F
-
E
P
------
N
K
A
Y
D
Y
A
-------------
Y
-------
A
N
-----
R
-
G
T
K
--
E
D
---
D
F
K
D
V
K
G
K
I
A
L
I
E
R
G
D
-----
I
D
F
K
D
K
I
A
K
A
K
K
A
G
A
V
G
V
L
I
Y
D
N
Q
D
K
G
F
P
I
E
--
L
---
P
N
V
-
D
Q
M
P
A
A
F
I
S
R
K
D
G
L
L
L
K
D
N
-------
P
Q
-----
K
T
-
I
T
F
N
A
T
P
K
V
L
P
T
A
S
G
T
K
L
S
R
F
S
S
W
G
--
L
T
A
D
--
G
N
I
K
P
D
I
A
A
P
G
Q
D
I
L
S
--------------
S
V
A
----------------------------------
N
------------------
N
--------------
K
Y
A
K
L
S
G
T
S
M
S
A
P
L
V
A
G
I
M
G
L
L
Q
K
Q
Y
E
T
Q
-
Y
---------
P
D
M
T
P
S
E
R
--
L
D
L
A
K
K
V
L
M
S
S
A
T
A
L
Y
D
E
-------
D
-------
E
--------------------------
K
A
Y
F
S
P
R
Q
Q
G
A
G
A
V
D
A
K
K
A
--------
S
A
A
T
M
Y
V
T
D
-----------------------------------
K
--
D
N
T
S
S
K
V
H
L
N
-
N
V
---------------------------
S
-----
D
---
K
F
E
V
T
V
N
V
H
N
K
S
D
K
P
Q
E
L
Y
Y
Q
A
T
V
-----
Q
T
D
K
V
D
G
K
H
F
A
L
A
P
K
V
L
Y
E
T
S
W
Q
K
I
T
I
P
A
N
-
S
-
S
K
Q
V
T
V
P
I
D
A
S
R
F
S
K
D
L
L
A
Q
M
K
N
G
Y
F
L
E
G
F
V
R
F
K
Q
-
D
P
T
K
E
E
L
M
S
I
P
Y
I
G
F
R
G
D
F
G
N
L
S
A
L
E
K
P
I
Y
D
S
K
D
G
S
S
Y
Y
H
E
A
N
-
S
D
A
K
D
Q
L
D
-
G
D
G
L
-
Q
F
Y
A
LK
N
N
F
T
A
L
T
T
E
S
N
P
W
T
I
I
K
A
V
K
E
G
V
E
NIED
I
---
E
-
S
S
E
I
T
E
T
I
F
A
G
T
F
A
-
K
Q
D
D
D
S
H
Y
Y
I
H
R
H
A
N
G
K
P
Y
A
A
I
S
P
N
G
D
G
N
R
D
Y
V
Q
F
Q
G
T
F
L
R
N
A
K
N
L
V
A
E
V
L
D
K
E
G
N
V
V
W
T
S
E
V
T
E
Q
V
V
K
N
Y
N
N
D
L
A
S
T
L
G
S
T
R
F
E
K
T
R
W
D
G
K
D
K
D
G
K
V
V
A
N
G
T
Y
T
Y
R
V
R
Y
T
P
I
S
S
G
A
K
E
Q
H
T
D
F
D
V
I
V
D
N
T
T
P
E
V
A
T
S
A
T
F
S
T
E
D
R
R
L
T
L
A
S
K
P
K
T
S
Q
--
P
V
Y
R
E
R
I
A
Y
T
Y
--
M
D
E
---
D
L
P
T
T
E
Y
I
S
P
N
E
D
G
T
F
T
L
P
E
E
A
E
T
M
E
G
A
T
-
V
P
L
K
M
S
D
F
T
Y
V
V
E
D
M
A
G
N
I
T
Y
T
P
V
T
K
L
L
E
G
H
------------------------------------------------------------------------------------------------------------------------------------
134
HHSearch
59.94
20%
-33
- C2 -
3I6S
3
?
A:
[13-643]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
G
-
L
W
P
-
A
-
S
G
L
G
Q
D
V
I
V
A
V
L
D
S
G
I
W
P
E
S
A
S
F
Q
D
D
G
M
P
E
I
P
K
R
W
K
G
I
C
--------
K
P
G
T
Q
F
N
A
S
M
C
N
R
K
L
I
G
A
N
Y
F
N
K
G
I
L
A
N
D
P
---
T
V
N
I
T
M
N
S
A
R
D
T
D
G
H
G
T
H
C
A
S
I
T
A
G
N
-
F
A
K
G
V
S
HFGY
A
P
G
---
T
A
R
G
V
A
P
R
--
A
R
L
A
V
Y
K
F
S
F
N
E
--------
G
T
F
T
S
D
L
I
A
A
M
-
D
Q
A
V
--------------------
A
D
-
G
-----
V
D
M
I
S
I
S
Y
G
Y
R
F
I
P
L
--------
Y
E
D
A
I
S
I
A
S
F
G
--
A
-----
M
M
K
G
V
L
V
S
A
S
A
G
N
R
G
P
G
I
---------------------
G
S
L
N
N
G
S
--
P
W
I
L
C
V
A
S
G
H
T
D
R
T
F
A
G
T
L
T
L
-
G
N
------
G
----
L
--
K
-
I
R
---------------
G
W
S
L
F
P
A
R
A
F
------
V
R
D
S
P
V
I
-------------
Y
-------
N
K
TLS--
D
-
C
S
S
--
E
E
L
L
S
Q
V
E
N
P
E
N
T
I
V
I
C
D
D
N
------
G
D
F
S
D
Q
M
R
I
I
T
R
A
R
L
K
A
A
I
F
I
S
E
D
P
G
V
F
R
----
S
---
A
-
T
-
F
P
N
P
G
V
V
V
N
K
K
E
G
K
Q
V
I
-
N
Y
V
K
N
S
VT
P
T
-----
A
T
-
I
T
F
Q
E
T
--
Y
L
D
T
K
P
A
P
V
V
A
A
S
S
A
R
G
--
P
S
R
S
YL
G
I
S
K
P
D
I
L
A
P
G
V
L
I
L
A
--------------
A
Y
P
----------------------------------
P
------------------
N
VFATSIGTN
I
L
L
S
T
D
Y
I
L
E
S
G
T
S
M
A
A
P
H
A
A
G
I
A
A
M
L
K
A
----
A
-
H
---------
P
E
--
W
S
P
S
A
----
I
R
S
A
M
M
T
T
A
D
P
L
D
N
T
RKPIKDS
D
-------
N
--------------------------
N
K
A
A
T
P
L
D
M
G
A
G
H
V
D
P
N
R
A
--------
L
D
P
G
L
V
Y
D
A
T
P
Q
D
Y
V
N
L
L
C
S
LNFT
E
E
Q
F
K
T
I
ARSSASHCSNPSA
D
--
L
N
-
Y
P
S
F
I
A
L
Y
S
I
---------------------------
E
GNF
T
L
L
---
E
Q
K
F
K
R
T
V
T
N
V
G
--
A
A
T
Y
K
A
K
L
K
A
-----
P
----
K
N
S
T
I
S
V
S
--------
P
Q
I
L
-
V
F
K
N
-
N
E
K
Q
S
Y
T
L
T
I
R
Y
I
G
D
-----------
S
R
N
V
G
S
I
T
W
V
E
Q
N
--
G
N
H
S
V
R
S
P
I
V
T
S
P
I
I
E
V
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
158
HHSearch
58.80
34%
-31
- C2 -
1THM
6
THET_THEVU
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
Y
G
P
Q
K
I
Q
A
P
Q
-
A
W
D
-
I
--
A
E
G
S
G
A
K
I
A
I
V
D
T
G
V
Q
S
N
H
P
D
L
A
G
K
V
-----------------------------------
V
G
G
W
D
F
V
D
N
D
S
T
--------------
P
Q
N
G
N
G
H
G
T
H
C
A
G
I
A
A
A
V
-
T
N
--------
N
S
T
---
G
I
A
G
T
A
P
K
--
A
S
I
L
A
V
R
V
L
D
N
S
------
G
-
S
G
T
W
T
A
V
A
N
G
I
-
T
Y
A
A
--------------------
D
Q
-
G
-----
A
K
V
I
S
L
S
L
G
G
T
V
G
-----------
N
S
G
L
Q
Q
A
V
N
Y
--
A
-----
W
N
K
G
S
V
V
V
A
A
A
G
N
A
G
N
T
A
---------------------
P
N
Y
P
A
Y
Y
--
S
N
A
I
A
V
A
S
T
D
Q
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
K
S
S
F
S
T
Y
G
--
S
W
--------
V
D
V
A
A
P
G
S
S
I
Y
S
--------------
T
Y
P
----------------------------------
T
------------------
S
--------------
T
Y
A
S
L
S
G
T
S
M
A
T
P
H
V
A
G
V
A
G
L
L
A
S
----
Q
------------
G
--
R
S
A
S
N
----
I
R
A
A
I
E
N
T
A
D
K
I
S
G
T
-----------------------------------------------
G
T
Y
W
A
K
G
R
V
N
A
Y
K
A
--------
V
Q
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
151
HHSearch
56.71
32%
-29
- C2 -
1R0R
4
SUBT_BACLI
E:
[4-274]
-------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
Y
G
I
P
L
I
K
A
D
K
-
V
Q
A
-
Q
-
G
F
K
G
A
N
V
K
V
A
V
L
D
T
G
I
Q
A
S
H
P
D
L
N
V
V
G
-------------------------------------
G
A
S
F
V
A
G
E
A
Y
--------------
N
T
D
G
N
G
H
G
T
H
V
A
G
T
V
A
A
L
-
D
---------
N
T
T
---
G
V
L
G
V
A
P
S
--
V
S
L
Y
A
V
K
V
L
N
S
S
------
G
-
S
G
S
Y
S
G
I
V
S
G
I
-
E
W
A
T
--------------------
T
N
-
G
-----
M
D
V
I
N
M
S
L
G
G
A
S
-----------
G
S
T
A
M
K
Q
A
V
D
N
--
A
-----
Y
A
R
G
V
V
V
V
A
A
A
G
N
S
G
N
S
G
S
-----------------
T
N
T
I
G
Y
P
A
K
Y
--
D
S
V
I
A
V
G
A
V
D
S
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
R
A
S
F
S
S
V
G
--
A
--------
E
L
E
V
M
A
P
G
A
G
V
Y
S
--------------
T
Y
P
----------------------------------
T
------------------
N
--------------
T
Y
A
T
L
N
G
T
S
M
A
S
P
H
V
A
G
A
A
A
L
I
L
S
----
K
-
H
---------
P
N
--
L
S
A
S
Q
----
V
R
N
R
L
S
S
T
A
T
Y
L
G
S
------------------------------------------------
S
F
Y
Y
G
K
G
L
I
N
V
E
A
A
--------
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
135
HHSearch
55.92
18%
-35
- C2 -
3VTA
3
CUCM1_CUCME
A:
[5-618]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
F
L
G
F
P
L
T
V
P
R
-
R
-
S
Q
V
E
S
N
I
V
V
G
V
L
D
T
G
I
W
P
E
S
P
S
F
D
D
E
G
F
S
P
P
P
P
K
W
K
G
T
C
E
T
-----------
S
N
N
F
R
C
N
R
K
I
I
G
A
R
S
Y
H
I
G
R
P
I
S
P
G
-------
D
V
N
G
P
R
D
T
N
G
H
G
T
H
T
A
S
T
A
A
G
G
-
L
V
S
Q
A
N
LYGL
G
L
G
---
T
A
R
G
G
V
P
L
--
A
R
I
A
A
Y
K
V
C
W
N
D
--------
G
C
S
D
T
D
I
L
A
A
Y
-
D
D
A
I
--------------------
A
D
-
G
-----
V
D
I
I
S
L
S
V
G
G
A
N
P
R
H
Y
-------
F
V
D
A
I
A
I
G
S
F
H
--
A
-----
V
E
R
G
I
L
T
S
N
S
A
G
N
G
G
P
N
F
---------------------
F
T
T
A
S
L
S
--
P
W
L
L
S
V
A
A
S
T
M
D
R
K
F
V
T
Q
V
Q
I
-
G
N
------
G
----
Q
--
S
-
F
Q
---------------
G
V
S
I
N
T
F
--
D
------
N
Q
Y
Y
P
L
V
S
GRDIPNTGFDKS
T
-------
S
R
-----
F
-
C
T
D
--
K
S
--
V
N
P
N
L
L
K
G
K
I
V
V
C
E
A
S
F
--------
G
P
H
E
F
F
K
S
L
D
G
A
A
G
V
L
M
T
S
N
T
R
D
Y
------
A
---
D
-
S
-
Y
P
L
P
S
S
V
L
D
P
N
D
L
L
A
T
L
-
R
Y
I
Y
S
I--
R
S
-----
P
G
-
A
T
I
F
K
S
T
-
T
I
L
N
A
S
A
P
V
V
V
S
F
S
S
R
G
--
P
N
R
A
TK
D
V
I
K
P
D
I
S
G
P
G
V
E
I
L
A
--------------
A
W
P
----------------------------------
S
VAPVGGIRRN--------
T
--------------
L
F
N
I
I
S
G
T
S
M
S
C
P
H
I
T
G
I
A
T
Y
V
K
T
----
Y
-
N
---------
P
T
--
W
S
P
A
A
----
I
K
S
A
L
M
T
T
A
S
P
M
N
A
R
------------------------------------------
F
N
P
Q
A
E
F
A
Y
G
S
G
H
V
N
P
L
K
A
--------
V
R
P
G
L
V
Y
D
A
NESDYVRVW--------------------------
D
--
L
N
-
Y
P
S
F
G
L
S
-
V
S
---------------------------
P
-----
S
Q
T
F
N
Q
Y
F
N
R
T
L
T
S
V
A
P
Q
A
S
T
Y
R
A
M
I
S
A
-----
P
----
Q
G
L
T
I
S
V
N
--------
P
N
V
L
-
S
F
N
G
L
G
D
R
K
S
F
T
L
T
V
R
G
S
I
----------
K
G
F
V
V
S
A
S
L
V
W
S
D
G
----
V
H
Y
V
R
S
P
I
T
I
T
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
154
HHSearch
55.32
24%
-14
- C2 -
3VV3
4
?
A:
[27-327]
------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
D
A
P
E
-
A
W
S
-
I
-
S
T
G
S
R
D
V
V
V
G
V
I
D
T
G
V
D
Y
S
H
P
D
L
A
A
N
A
W
V
N
S
--
G
E
----
I
A
-
G
D
G
I
D
N
----
D
G
N
G
Y
I
D
--
D
V
H
G
I
N
A
I
T
D
V
G
--------------
D
P
M
D
D
E
G
H
G
T
H
V
S
G
T
I
G
A
S
-
G
N
--------
N
G
V
---
G
V
V
G
V
N
H
D
--
V
S
I
V
G
C
K
F
L
A
A
D
------
G
-
T
G
S
T
S
G
A
I
K
C
I
-
D
Y
M
V
--------------------
G
L
-
K
N
A
GVN
L
R
V
L
N
N
S
W
G
G
G
G
-----------
F
S
Q
A
L
A
D
A
I
T
A
--
S
-----
E
Q
A
D
I
L
F
V
A
A
A
G
N
D
A
V
D
N
D
Q
------------------
N
P
H
Y
P
S
N
Y
EN
D
N
V
L
S
I
A
S
T
D
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
N
M
S
S
F
S
Q
W
G
--
L
T
-------
S
V
D
M
G
A
P
G
S
G
I
L
S
--------------
T
V
P
----------------------------------
G
------------------
N
--------------
S
Y
A
T
Y
S
G
T
S
M
A
T
P
H
V
A
G
A
A
A
L
V
L
S
----
V
-
N
---------
P
D
--
L
T
T
L
E
----
L
K
E
L
L
M
S
S
G
D
A
N
A
A
L
----------------------------------------------
N
G
K
T
V
A
G
T
R
L
N
V
N
Q
A
--------
L
I
D
A
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
145
HHSearch
55.28
28%
-26
- C2 -
2Z30
7
TKSU_THEKO
A:
[7-317]
------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
P
W
G
I
E
R
V
K
A
P
S
-
V
W
S
-
I
T
D
G
S
V
S
V
I
Q
V
A
V
L
D
T
G
V
D
Y
D
H
P
D
L
A
A
N
I
A
-----------------------------------
W
C
V
S
T
L
R
G
K
V
S
T
K
L
---------
R
D
C
A
D
Q
N
G
H
G
T
H
V
I
G
T
I
A
A
L
-
N
---------
N
D
I
---
G
V
V
G
V
A
P
G
--
V
Q
I
Y
S
V
R
V
L
D
A
R
------
G
-
S
G
S
Y
S
D
I
A
I
G
I
-
E
Q
A
I
L
GPDGVADKDGDGIIAGDPD
D
D
-
A
-----
A
E
V
I
S
M
S
L
G
G
P
A
D
-----------
D
S
Y
L
Y
D
M
I
I
Q
--
A
-----
Y
N
A
G
I
V
I
V
A
A
S
G
N
E
G
A
P
S
---------------------
P
S
Y
P
A
A
Y
--
P
E
V
I
A
V
G
A
I
D
S
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
I
A
S
F
S
N
R
------------
Q
P
E
V
S
A
P
G
V
D
I
L
S
--------------
T
Y
P
----------------------------------
D
------------------
D
--------------
S
Y
E
T
L
M
G
T
A
M
A
T
P
H
V
S
G
V
V
A
L
I
Q
A
A
Y
Y
Q
K
-
Y
GKILPVGTF
D
D
--
I
S
K
N
T
----
V
R
G
I
L
H
I
T
A
D
D
L
G
P
T
---------------------------------------------
G
W
D
A
D
Y
G
Y
G
V
V
R
A
A
L
A
--------
V
Q
A
A
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
140
HHSearch
54.88
30%
-30
- C2 -
3WHI
1
?
A:
[92-365]
-----------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
V
P
Y
G
I
S
Q
I
K
A
P
A
-
L
H
S
-
Q
-
G
Y
T
G
S
N
V
K
V
A
V
I
D
S
G
I
D
S
S
H
P
D
L
N
V
R
G
-------------------------------------
G
A
S
F
V
P
S
E
T
N
P
-------------
Y
Q
D
G
S
S
H
G
T
H
V
A
G
T
I
A
A
L
-
N
---------
N
S
I
---
G
V
L
G
V
S
P
S
--
A
S
L
Y
A
V
K
V
L
D
S
T
------
G
-
S
G
Q
Y
S
W
I
I
N
G
I
-
E
W
A
I
--------------------
S
N
-
N
-----
M
D
V
I
N
M
S
L
G
G
P
T
G
-----------
S
T
A
L
K
T
V
V
D
K
--
A
-----
V
S
S
G
I
V
V
A
A
A
A
G
N
E
G
S
S
G
S
-----------------
T
S
T
V
G
Y
P
A
K
Y
--
P
S
T
I
A
V
G
A
V
N
S
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
R
A
S
F
S
S
A
G
--
S
E
--------
L
D
V
M
A
P
G
V
S
I
Q
S
--------------
T
L
P
----------------------------------
G
------------------
G
--------------
T
Y
G
A
Y
N
G
T
A
M
A
T
P
H
V
A
G
A
A
A
L
I
L
S
----
K
-
H
---------
P
T
--
W
T
N
A
Q
----
V
R
D
R
L
E
S
T
A
T
Y
L
G
------------------------------------------------
N
S
F
Y
Y
G
K
G
L
I
N
V
Q
A
A
--------
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
155
HHSearch
54.82
31%
-33
- C2 -
1TO2
7
SUBT_BACAM
E:
[5-276]
--------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
G
V
S
Q
I
K
A
P
A
-
L
H
S
-
Q
-
G
Y
T
G
S
N
V
K
V
A
V
I
D
S
G
I
D
S
S
H
P
D
L
K
V
A
G
-------------------------------------
G
A
S
M
V
P
S
E
T
N
P
-------------
F
Q
D
N
N
S
H
G
T
H
V
A
G
T
V
A
A
L
-
N
---------
N
S
I
---
G
V
L
G
V
A
P
S
--
A
S
L
Y
A
V
K
V
L
G
A
D
------
G
-
S
G
Q
Y
S
W
I
I
N
G
I
-
E
W
A
I
--------------------
A
N
-
N
-----
M
D
V
I
N
M
S
L
G
G
P
S
-----------
G
S
A
A
L
K
A
A
V
D
K
--
A
-----
V
A
S
G
V
V
V
V
A
A
A
G
N
E
G
T
S
G
S
-----------------
S
S
T
V
G
Y
P
G
K
Y
--
P
S
V
I
A
V
G
A
V
D
S
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
R
A
S
F
S
S
V
G
--
P
--------
E
L
D
V
M
A
P
G
V
S
I
Q
S
--------------
T
L
P
----------------------------------
G
------------------
N
--------------
K
Y
G
A
Y
N
G
T
S
M
A
S
P
H
V
A
G
A
A
A
L
I
L
S
----
K
-
H
---------
P
N
--
W
T
N
T
Q
----
V
R
S
S
L
E
N
T
T
T
K
L
G
D
------------------------------------------------
S
F
Y
Y
G
K
G
L
I
N
V
Q
A
A
--------
A
Q
H
H
H
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
165
Fugue
54.46
20%
-24
- C2 -
3I6S
3
?
A:
[1-649]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
T
H
T
S
D
F
L
K
L
N
P
S
S
G
-
L
W
P
-
A
-
S
G
L
G
Q
D
V
I
V
A
V
L
D
S
G
I
W
P
E
S
A
S
F
Q
D
D
G
M
P
E
I
P
K
R
W
K
G
I
C
K
P
G
T
Q
F
N
A
S
M
C
--------
N
R
K
L
I
G
A
N
Y
F
---
N
K
G
I
L
A
N
D
P
T
V
N
I
T
M
N
S
A
R
D
T
D
G
H
G
T
H
C
A
S
I
T
A
G
N
F
A
K
G
V
S
H
----
F
G
Y
AP
G
T
A
R
G
V
A
P
R
--
A
R
L
A
V
Y
K
F
--
S
F
-----
N
E
-
G
T
F
T
S
D
L
I
A
A
M
-
D
Q
A
V
--------------------
A
D
-
G
-----
V
D
M
I
S
I
S
Y
G
Y
R
F
I
P
L
Y
--
E
------
D
A
I
S
I
A
S
F
G
--
A
-----
M
M
K
G
V
L
V
S
A
S
A
G
N
R
G
-------------------
P
G
I
G
S
L
N
N
G
S
P
W
----
I
L
C
V
A
S
G
H
T
D
R
T
F
A
G
T
L
T
L
-
G
N
------
G
L
K
-
I
R
--
G
-
W
S
---------------
L
F
P
A
R
A
F
-
V
R
------
D
--
S
P
V
I
-------------
Y
-------
N
K
TLSDC
S
-
S
E
E
--
L
L
--
S
Q
V
E
N
P
E
N
T
I
V
I
C
D
D
N
G
------
D
F
S
D
Q
M
R
I
I
T
R
A
R
L
K
A
A
I
F
I
S
E
D
P
G
V
F
R
----
S
---
A
-
T
-
F
P
N
P
G
V
V
V
N
K
K
E
G
K
Q
V
I
-
N
-------
Y
V
K
N
S
VT
P
T
-
A
T
I
T
F
Q
E
T
Y
L
D
T
K
P
A
P
V
V
A
A
S
S
A
R
G
PS
R
S
Y
L
--
G
I
S
K
P
D
I
L
A
P
G
V
L
I
L
A
A
Y
PPNVFATSIGTN
I
L
L
----------------------------------
S
------------------
T
--------------
D
Y
I
L
E
S
G
T
S
M
A
A
P
H
A
A
G
I
A
A
M
L
K
A
A
H
P
E
W
-
S
------------
P
S
A
I
R
S
A
M
M
T
T
A
D
P
L
D
N
T
R
K
P
I
K
D
S
-------
D
-------
N
--------------------------
N
K
A
A
T
P
L
D
M
G
A
G
H
V
D
P
N
R
A
L
D
PGLVYD
A
T
P
Q
D
Y
V
N
L
-----------------------------------
L
C
S
L
N
-
F
T
E
E
Q
F
K
-
T
I
ARSSASHCSNPSADLNYP
S
F
I
A
L
Y
S
IE
G
-----
N
---
F
T
L
L
E
Q
K
F
K
R
T
V
T
N
V
G
A
A
T
Y
K
A
K
L
K
A
P
K
N
S
T
I
S
V
S
P
Q
I
L
V
F
K
N
N
E
K
Q
S
Y
T
L
T
I
R
-
Y
I
G
D
-
S
-
R
N
V
G
S
I
T
W
V
E
Q
N
G
N
H
S
V
R
S
P
I
V
T
S
P
I
I
E
V
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
139
HHSearch
54.43
28%
-22
- C2 -
1WMD
6
?
A:
[3-319]
---------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
R
G
I
V
K
A
D
V
-
A
Q
S
S
Y
-
G
L
Y
G
Q
G
Q
I
V
A
V
A
D
T
G
L
D
T
G
R
N
D
S
S
M
H
E
A
F
-----------------------------
R
G
K
I
T
A
L
Y
A
L
G
R
T
N
N
---------------
A
N
D
T
N
G
H
G
T
H
V
A
G
S
V
L
G
N
-
G
-----------
S
---
T
N
K
G
M
A
P
Q
--
A
N
L
V
F
Q
S
I
M
D
S
G
-----
G
G
L
G
G
L
P
S
N
L
Q
T
L
F
-
S
Q
A
Y
--------------------
S
A
-
G
-----
A
R
I
H
T
N
S
W
G
A
A
V
N
G
A
--------
Y
T
T
D
S
R
N
V
D
D
Y
--
V
-----
R
K
N
D
M
T
I
L
F
A
A
G
N
E
G
P
N
G
-------------------
G
T
I
S
A
P
G
T
A
--
K
N
A
I
T
V
G
A
T
E
N
L
R
P
S
F
-----------------------------------------------------------------------------------------------------------------------
G
S
-------------------------------------------------------------------------------------------
Y
A
D
N
I
N
H
V
A
Q
F
S
S
R
G
--
P
T
K
D
--
G
R
I
K
P
D
V
M
A
P
G
T
F
I
L
S
--------------
A
R
S
SLAPDSSFWANH----------------------
D
------------------
S
--------------
K
Y
A
Y
M
G
G
T
S
M
A
T
P
I
V
A
G
N
V
A
Q
L
R
E
H
F
V
K
N
R
G
---------
I
T
--
P
K
P
S
----
L
L
K
A
A
L
I
A
G
A
A
D
I
G
L
---------------------------------------------
G
Y
P
N
G
N
Q
G
W
G
R
V
T
L
D
K
S
--------
L
N
V
A
Y
V
N
E
S
-----------------------------------
S
--
S
L
-
S
T
S
Q
K
A
T
-
Y
S
---------------------------
F
-----
T
---
A
T
A
G
K
P
L
K
I
S
L
V
W
S
D
A
P
A
S
T
T
A
S
V
-----
T
L
V
N
D
L
D
L
V
I
T
A
P
N
G
T
Q
Y
V
G
N
D
F
T
S
-
P
Y
N
D
-
N
-
W
D
G
R
N
N
V
E
N
V
F
I
N
A
P
Q
S
G
T
Y
T
I
E
V
Q
A
Y
N
V
P
V
G
P
Q
T
F
S
L
A
I
V
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137
HHSearch
54.38
28%
-29
- C2 -
1R6V
1
?
A:
[132-441]
-----------------------------------------------------------------------------------------------------------------------------------------------------
S
N
E
L
W
G
L
E
A
I
G
V
T
Q
-
Q
L
W
-
E
-
E
A
S
G
T
N
I
I
V
A
V
V
D
T
G
V
D
G
T
H
P
D
L
E
G
Q
V
I
-----------------------------------
A
G
Y
R
P
A
F
D
E
E
L
P
A
G
---------
T
D
S
S
Y
G
G
S
A
G
T
H
V
A
G
T
I
A
A
K
-
K
---------
D
G
K
---
G
I
V
G
V
A
P
G
--
A
K
I
M
P
I
V
I
F
D
D
P
ALVGG
N
G
-
Y
V
G
D
D
Y
V
A
A
G
I
-
I
W
A
T
--------------------
D
H
-
G
-----
A
K
V
M
N
H
S
W
G
G
W
G
-----------
Y
S
Y
T
M
K
E
A
F
D
Y
--
A
-----
M
E
H
G
V
V
M
V
V
S
A
G
N
N
T
S
D
S
--------------------
H
H
Q
Y
P
A
G
Y
--
P
G
V
I
Q
V
A
A
L
D
Y
Y
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
F
R
V
A
G
F
S
S
R
S
--
D
G
--------
V
S
V
G
A
P
G
V
T
I
L
S
--------------
T
V
P
----------------------------------
G
EDSIGYEGHNENVPATNG
G
--------------
T
Y
D
Y
Y
Q
G
T
S
M
A
A
P
H
V
T
G
V
V
A
V
L
L
Q
----
K
-
F
---------
P
N
--
A
K
P
W
Q
----
I
R
K
L
L
E
N
T
A
F
D
F
N
G
N
---------------------------------------------
G
W
D
H
D
T
G
Y
G
L
V
K
L
D
A
A
--------
L
Q
G
P
L
P
T
Q
G
-----------------------------------
G
--
V
E
-
E
F
Q
V
V
V
T
-
D
A
---------------------------
K
-----
G
---
N
F
G
V
P
T
V
F
V
S
M
M
R
D
N
G
S
C
Y
Y
A
K
T
G
-----
P
D
G
I
A
R
F
P
H
I
D
S
G
T
Y
D
I
F
V
G
G
P
D
H
W
-
D
R
A
L
-
A
-
P
Y
D
G
E
S
I
P
G
G
Y
A
I
A
L
R
M
A
E
E
R
Q
A
S
F
V
G
F
G
V
S
P
D
A
T
Q
L
N
V
N
F
N
S
T
L
Q
V
K
F
S
T
N
L
S
T
L
K
D
P
Q
F
V
V
V
D
P
L
L
R
G
V
Y
G
R
V
A
Y
A
R
N
Q
T
Y
D
L
S
L
L
S
G
Q
I
S
-
F
G
I
Q
--
T
L
L
P
A
A
T
D
I
T
I
Q
G
T
V
T
L
N
G
E
D
I
P
V
----
Y
---
G
V
L
K
A
G
T
T
W
T
I
I
D
D
F
G
G
L
N
L
G
T
D
S
Q
P
I
Y
V
W
W
T
I
F
G
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
138
HHSearch
53.75
28%
-26
- C2 -
3WIU
6
TKSU_THEKO
A:
[84-395]
-----------------------------------------------------------------------------------------------------------------------------------------------------
Q
T
I
P
W
G
I
E
R
V
K
A
P
S
-
V
W
S
-
I
T
D
G
S
V
S
V
I
Q
V
A
V
L
D
T
G
V
D
Y
D
H
P
D
L
A
A
N
I
A
-----------------------------------
W
C
V
S
T
L
R
G
K
V
S
T
K
L
---------
R
D
C
A
D
Q
N
G
H
G
T
H
V
I
G
T
I
A
A
L
-
N
---------
N
D
I
---
G
V
V
G
V
A
P
G
--
V
Q
I
Y
S
V
R
V
L
D
A
R
------
G
-
S
G
S
Y
S
D
I
A
I
G
I
-
E
Q
A
I
L
GPDGVADKDGDGIIAGDPD
D
D
-
A
-----
A
E
V
I
S
M
S
L
G
G
P
A
D
-----------
D
S
Y
L
Y
D
M
I
I
Q
--
A
-----
Y
N
A
G
I
V
I
V
A
A
S
G
N
E
G
A
P
---------------------
S
P
S
Y
P
A
A
Y
--
P
E
V
I
A
V
G
A
I
D
S
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
I
A
S
F
S
N
R
Q
------------
P
E
V
S
A
P
G
V
D
I
L
S
--------------
T
Y
P
----------------------------------
D
------------------
D
--------------
S
Y
E
T
L
M
G
T
A
M
A
T
P
H
V
S
G
V
V
A
L
I
Q
A
A
Y
Y
Q
K
-
Y
GKIAPVGTF
D
D
--
I
S
K
N
T
----
V
R
G
I
L
H
I
T
A
D
D
L
G
P
T
---------------------------------------------
G
W
D
A
D
Y
G
Y
G
V
V
R
A
A
L
A
--------
V
Q
A
A
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
157
HHSearch
53.46
31%
-25
- C2 -
1DBI
4
THES_BACSJ
A:
[8-279]
----------------------------------------------------------------------------------------------------------------------------------------------------
Y
Q
G
Y
Q
Y
G
P
Q
N
T
Y
T
D
Y
-
A
W
D
-
V
-
T
K
G
S
S
G
Q
E
I
A
V
I
D
T
G
V
D
Y
T
H
P
D
L
D
G
K
V
-----------------------------------
I
K
G
Y
D
F
V
D
N
D
Y
D
--------------
P
M
D
L
N
N
H
G
T
H
V
A
G
I
A
A
A
E
-
T
N
--------
N
A
T
---
G
I
A
G
M
A
P
N
--
T
R
I
L
A
V
R
A
L
D
R
N
------
G
-
S
G
T
L
S
D
I
A
D
A
I
-
I
Y
A
A
--------------------
D
S
-
G
-----
A
E
V
I
N
L
S
L
G
C
D
C
H
-----------
T
T
T
L
E
N
A
V
N
Y
--
A
-----
W
N
K
G
S
V
V
V
A
A
A
G
N
N
------------------------------
S
Y
--
E
N
V
I
A
V
G
A
V
D
Q
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
L
A
S
F
S
N
Y
G
--
T
--------
W
V
D
V
V
A
P
G
V
D
I
V
S
--------------
T
I
T
----------------------------------
G
------------------
N
--------------
R
Y
A
Y
M
S
G
T
S
M
A
S
P
H
V
A
G
L
A
A
L
L
A
S
----
Q
-
G
---------
R
----
N
N
I
E
----
I
R
Q
A
I
E
Q
T
A
D
K
I
S
G
-----------------------------------------------
T
G
T
Y
F
K
Y
G
R
I
N
S
Y
N
A
--------
V
T
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
147
HHSearch
52.61
27%
-16
- C2 -
3LPC
8
?
A:
[18-337]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
K
A
D
K
-
V
W
D
-
M
-
G
F
T
G
Q
N
V
V
V
A
V
V
D
T
G
I
-
L
H
H
R
D
L
N
A
N
V
L
P
G
--
Y
D
F
I
S
N
S
Q
I
-
S
L
----
D
----
G
D
G
R
D
A
D
P
F
D
E
G
D
W
F
D
N
W
A
C
G
G
R
P
------
D
P
R
K
E
R
S
D
S
S
W
H
G
S
H
V
A
G
T
I
A
A
V
-
T
N
--------
N
R
I
---
G
V
A
G
V
A
Y
G
--
A
K
V
V
P
V
R
A
L
G
R
C
-----
G
---
G
Y
D
S
D
I
S
D
G
L
-
Y
W
A
A
GGRIAGIPEN----------
R
N
-
P
-----
A
K
V
I
N
M
S
L
G
S
D
G
Q
C
----------
S
Y
N
A
Q
T
M
I
D
R
--
A
-----
T
R
L
G
A
L
V
V
V
A
A
G
N
E
N
Q
N
A
--------------------
S
N
T
W
P
T
S
C
--
N
N
V
L
S
V
G
A
T
T
S
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
R
A
S
F
S
N
Y
G
--
V
--------
D
V
D
L
A
A
P
G
Q
D
I
L
S
--------------
T
V
D
----------------------------------
S
GTRRPV
S
-----------
D
--------------
A
Y
S
F
M
A
G
T
S
M
A
T
P
H
V
S
G
V
A
A
L
V
I
S
A
A
N
S
V
-
N
---------
K
N
--
L
T
P
A
E
----
L
K
D
V
L
V
S
T
T
S
P
F
N
G
----------------------------------------------
R
L
D
R
A
L
G
S
G
I
V
D
A
E
A
A
--------
V
N
S
V
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
146
HHSearch
52.37
23%
-19
- C2 -
2ID4
6
KEX2_YEAST
A:
[40-343]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
N
V
L
D
-
L
W
Y
-
N
-
N
I
T
G
A
G
V
V
A
A
I
V
D
D
G
L
D
Y
E
N
E
D
L
K
D
N
F
C
---------------------------------
A
E
G
S
W
D
F
N
D
N
T
N
L
P
K
P
-----------
R
L
S
D
D
Y
H
G
T
R
C
A
G
E
I
A
A
K
-
K
G
--------
N
N
F
---
C
G
V
G
V
G
Y
N
--
A
K
I
S
G
I
R
I
L
S
G
D
---------
I
T
T
E
D
E
A
A
S
L
-
I
Y
G
L
--------------------
D
--
V
-----
N
D
I
Y
S
C
S
W
G
P
A
D
D
G
R
H
L
Q
G
----
P
S
D
L
V
K
K
A
L
V
K
--
G
V
TEGR
D
S
K
G
A
I
Y
V
F
A
S
G
N
G
G
T
R
G
D
N
-----------------
C
N
Y
D
G
Y
T
N
S
--
I
Y
S
I
T
I
G
A
I
D
H
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
H
P
P
Y
S
E
G
C
--
S
A
V
M
--
A
--
V
T
Y
S
S
G
S
G
E
Y
I
H
S
--------------
S
D
I
----------------------------------
N
G-----------------
R
--------------
C
S
N
S
H
G
G
T
S
A
A
A
P
L
A
A
G
V
Y
T
L
L
L
E
----
A
-
N
---------
P
N
--
L
T
W
R
D
----
V
Q
Y
L
S
I
L
S
A
V
G
L
E
K
N
-------
A
DG
D
W
R
D
S
A
--------------------------
M
G
K
K
Y
S
H
R
Y
G
F
G
K
I
D
A
H
K
L
--------
I
E
M
S
K
T
W
E
N
-----------------------------------
V
--
N
A
-
Q
T
W
F
Y
L
P
-
T
L
---------------------------
Y
-----
V
---
S
Q
S
T
N
S
T
E
E
T
L
E
S
V
I
T
I
S
E
K
S
L
Q
D
-----
A
N
F
K
R
I
E
H
V
T
V
T
V
D
I
D
T
E
I
R
G
T
T
T
V
-
D
L
I
S
-
P
-
A
G
I
I
S
N
L
G
V
V
R
P
R
D
V
S
S
E
G
F
K
D
W
T
F
M
S
V
A
H
W
G
E
N
G
V
G
D
W
K
I
K
V
K
T
T
E
N
G
H
R
I
D
F
H
S
W
R
L
K
L
F
G
E
S
I
D
S
S
K
T
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
148
HHSearch
51.59
22%
-25
- C2 -
3WQB
2
?
A:
[56-426]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
N
L
W
W
-
A
H
R
-
T
-
G
V
L
G
Q
G
V
N
V
A
V
V
D
D
G
L
A
I
A
H
P
D
L
A
D
N
V
R
----------------------------------
P
G
S
K
N
V
V
T
G
S
D
D
P
T
P
-----------
T
D
P
D
T
A
H
G
T
S
V
S
G
I
I
A
A
V
-
D
---------
N
A
I
---
G
T
K
G
I
A
P
R
--
A
Q
L
Q
G
F
N
L
L
D
D
N
------
S
-
Q
Q
L
Q
K
D
W
L
Y
A
L
G
D
S
N
A
--------------------
S
R
-
D
-----
N
R
V
F
N
Q
S
Y
G
M
S
V
V
D
P
R
--
S
ANS
L
D
Q
S
Q
L
D
R
L
F
E
Q
Q
T
L
-----
K
A
Q
G
A
A
Y
I
K
A
A
G
N
G
F
N
K
I
A
A
G
G
Y
V
L
N
R
T
G
N
G
P
K
L
P
F
E
N
S
N
L
D
P
S
N
S
N-
F
W
N
L
V
V
S
A
L
N
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
V
R
S
S
Y
S
S
V
G
--
S
N
--------
I
F
L
S
A
T
G
G
E
Y
G
T
--------------
D
T
P
A
M
V
T
T
D
LPGCDMGYNRTDDPSTNRLHGNSQLDAS
C
------------------
D
--------------
Y
N
G
V
M
N
G
T
A
S
A
T
P
S
T
S
G
A
M
A
L
L
M
S
----
A
-
Y
---------
P
D
--
L
S
V
R
D
----
L
R
D
L
L
A
R
S
A
T
R
V
D
A
K
-------
H
-------
Q
P
V
M
V
S
Y
T
S
STG
K
V
R
D
V
K
GLE
G
W
E
R
N
A
A
G
M
W
F
S
P
T
Y
G
F
G
L
I
D
V
N
K
A
--------
L
E
L
A
A
N
H
Q
P
-----------------------------------
L
--
P
P
-
L
V
Q
L
P
W
Q
-
K
I
---------------------------
N
-----
V
---
T
G
S
A
A
A
I
A
D
V
G
N
S
P
T
S
S
T
T
R
I
A
T
P
-----
L
T
V
E
A
V
Q
V
M
V
S
L
D
H
Q
R
L
P
D
L
L
I
E
L
V
-
S
P
A
G
-
T
-
R
S
I
L
L
S
P
F
N
S
L
V
G
Q
S
L
D
Q
Q
Q
L
G
F
V
R
T
K
G
L
R
D
M
R
M
L
S
N
K
F
Y
G
E
S
A
Q
G
T
W
R
L
E
V
T
D
V
A
N
G
T
R
Q
V
S
L
L
N
R
E
T
R
E
R
T
T
L
T
E
R
N
N
R
Q
P
G
K
L
I
S
W
S
L
R
V
-
L
G
H
D
--
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
142
HHSearch
51.55
24%
-21
- C2 -
1Y9Z
7
?
A:
[4-429]
-------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
W
G
Q
T
F
V
G
A
T
V
-
L
S
D
----
S
Q
A
G
N
R
T
I
C
I
I
D
S
G
Y
D
R
S
H
N
D
L
N
A
N
N
V
T
G
-----------------------------------
T
N
N
S
G
T
G
N
W
Y
------------
Q
P
G
N
N
N
A
H
G
T
H
V
A
G
T
I
A
A
I
-
A
---------
N
N
E
---
G
V
V
G
V
M
P
N
QN
A
N
I
H
I
V
K
V
F
N
E
A
------
G
-
W
G
Y
S
S
S
L
V
A
A
I
-
D
T
C
V
--------------------
N
S
G
G
-----
A
N
V
V
T
M
S
L
G
G
S
G
S
T
-----------
T
T
E
R
N
A
L
N
T
--
H
-----
Y
N
N
G
V
L
L
I
A
A
A
G
N
A
G
D
S
---------------------
S
Y
S
Y
P
A
S
Y
--
D
S
V
M
S
V
A
A
V
D
S
N
L
D
H
A
A
F
S
Q
Y
-
T
D
QVEISG
P
G
E
-
A
I
L
S
T
-
V
T
VGE
G
R
L
A
D
I
T
I
GGQS
Y
F
S
N
G
V
V
-
P
H
NRLTPS
G
T
S
Y
A
P
A
-------------
P
I
N
A
S
A
T
G
A
L
-----
A
E
C
T
V
NG
T
S
--
F
S
C
G
N
M
A
N
K
I
C
L
V
E
R
V
G
N
QGSS
Y
P
E
I
N
S
T
K
A
C
K
T
A
G
A
K
G
I
I
V
Y
S
N
S
A
L
P
G
L
Q
N
PF
L
VDA
N
S
D
-
I
T
V
P
S
V
S
V
D
R
A
T
G
L
A
L
K
-
A
-------------------------------------------------------
K
L
G
Q
--
S
T
T
V
S
--------------
N
Q
G
----------------------------------
N
------------------
Q
--------------
D
Y
E
Y
Y
N
G
T
S
M
A
T
P
H
V
S
G
V
A
T
L
V
W
S
----
Y
-
H
---------
P
E
--
C
S
A
S
Q
----
V
R
A
A
L
N
A
T
A
D
D
L
S
V
A
---------------------------------------------
G
R
D
N
Q
T
G
Y
G
M
I
N
A
V
A
A
--------
K
A
Y
L
D
E
S
C
T
-----------------------------------
G
--
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------