@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0661: (2015-12-02 )
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLNADVNVKAYVQNTIDNQQRPSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKGWDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNVAIPNTQASYTMDYATGEITLN
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------.........10.-----------.......--20........30...-------.....40.....---...50........60-----....-....70.-------.......80...-----.....---90--.---....------------....100.......110.......120.....------..130--...-.----...140....-...150...---....160.----......170...-.-...180---..-----.......190..-.------....200--.......210...---..-----..220.......230...---.-.------------------..240.......250.......260-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------M
K
R
L
H
K
L
F
I
T
V
I
-----------
A
T
L
G
M
L
G
--
V
M
TFGLPTQPQN
V
T
P
-------
I
V
H
ADVNSSVD
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
GNL-----
P
F
Q
Y
-
V
N
G
I
Y
E
L-------NNNQTNLNA
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---TIDN------------QQRP
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
QNRRDTTLPDANWK------PL
G
W
H
--
Q
VA-T----NDHYGHAVDK-G
H
L
I
A
Y
A
LA---GNFKGWDA----SVS
N
P
Q
N
V
V
T
QT-A-HSNQ-----SN-----QKINR
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
AVDQ--NK
R
V
R
Y
R
V
T
P
L
YR---ND-----TD
L
V
P
F
A
M
H
L
E
AKSQDG
T
---
L
-
E
------------------
F
N
V
AIPNTQ
A
S
Y
T
M
D
YAT
G
E
I
T
LN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
99.34
99%
-57
- C4 -
4QH0
7
?
D:
[6-225]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
-------
A
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.99
99%
-56
- C4 -
4QGO
8
?
A:
[6-225]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
R
-------
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
98.59
99%
-54
- C4 -
4QH0
8
?
C:
[6-225]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
R
-----
D
A
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_CBE
98.52
99%
-56
- C4 -
4QGO
8
?
B:
[6-225]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
R
-------
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
97.68
99%
-54
- C4 -
4QH0
15
?
A:
[7-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
R
D
T
T
L
P
D
A
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_CBE
97.08
99%
-51
- C4 -
4QH0
14
?
B:
[7-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
D
T
---
S
Q
E
F
Q
N
N
L
K
N
A
I
G
N
L
-----
P
F
Q
Y
-
V
N
G
I
Y
E
L
-------
N
N
N
Q
T
N
L
N
A
D
V
N
-----
V
K
A
Y
V
---
Q
---
N
---
T
I
D
N
------------
Q
Q
R
P
S
T
A
N
A
M
L
D
R
T
I
R
Q
Y
Q
N
R
R
D
T
T
L
P
D
A
N
W
K
------
P
L
G
W
H
--
Q
V
A
-
T
----
N
D
H
Y
G
H
A
V
D
K
-
G
A
L
I
A
Y
A
L
A
---
G
N
F
K
G
W
D
A
----
S
V
S
N
P
Q
N
V
V
T
Q
T
-
A
-
H
S
N
Q
-----
S
N
-----
Q
K
I
N
R
G
Q
N
Y
Y
E
S
-
L
------
V
R
K
A
V
D
Q
--
N
K
R
V
R
Y
R
V
T
P
L
Y
R
---
N
D
-----
T
D
L
V
P
F
A
M
H
L
E
A
K
S
Q
D
G
T
---
L
-
E
------------------
F
N
V
A
I
P
N
T
Q
A
S
Y
T
M
D
Y
A
T
G
E
I
T
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
77.55
44%
-39
- C4 -
3OWV
3
NUCE_STRPN
A:
[20-247]
--------------------------------------------------------------------------------------------------------------------------------------------------
S
E
A
P
S
Q
A
L
A
---
E
S
V
L
T
D
A
V
K
S
Q
I
K
G
------
S
L
E
W
N
G
S
G
A
F
I
V
-------
N
G
N
K
T
N
L
D
A
K
V
S
-----
S
K
P
Y
A
---
D
N
K
T
K
---
T
V
G
K
------------
E
T
V
P
T
V
A
N
A
L
L
S
K
A
T
R
Q
Y
-----------
S
W
T
------
P
P
G
W
H
--
Q
V
K
-
N
L---
K
G
S
Y
T
H
A
V
D
R
-
G
A
L
L
G
Y
A
L
I
---
G
G
L
D
G
F
D
A
----
S
T
S
N
P
K
N
I
A
V
Q
T
-
A
-
W
A
N
Q
-----
A
Q
-----
A
E
Y
S
T
G
Q
N
Y
Y
E
S
-
K
------
V
R
K
A
L
D
Q
--
N
K
R
V
R
Y
R
V
T
L
Y
Y
A
---
S
N
-----
E
D
L
V
P
S
A
S
Q
I
E
A
K
S
S
D
G
E
---
L
-
E
------------------
F
N
V
L
V
P
N
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.43
51%
-46
- C4 -
3OWV
3
NUCE_STRPN
A:
[49-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
A
F
I
V
-------
N
G
N
K
T
N
L
D
A
K
V
S
-----
S
K
P
Y
A
---
D
---
N
K
T
K
T
V
G
K
------------
E
T
V
P
T
V
A
N
A
L
L
S
K
A
T
R
Q
Y
-----------
S
W
T
------
P
P
G
W
H
--
Q
V
K
-
N
L---
K
G
S
Y
T
H
A
V
D
R
-
G
A
L
L
G
Y
A
L
I
---
G
G
L
D
G
F
D
A
----
S
T
S
N
P
K
N
I
A
V
Q
T
-
A
-
W
A
N
Q
-----
A
Q
-----
A
E
Y
S
T
G
Q
N
Y
Y
E
S
-
K
------
V
R
K
A
L
D
Q
--
N
K
R
V
R
Y
R
V
T
L
Y
Y
A
---
S
N
-----
E
D
L
V
P
S
A
S
Q
I
E
A
K
S
S
D
G
E
---
L
-
E
------------------
F
N
V
L
V
P
N
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
76.81
51%
-47
- C4 -
3OWV
4
NUCE_STRPN
B:
[49-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
A
F
I
V
-------
N
G
N
K
T
N
L
D
A
K
V
S
-----
S
K
P
Y
A
---
D
---
N
K
T
K
T
V
G
K
------------
E
T
V
P
T
V
A
N
A
L
L
S
K
A
T
R
Q
Y
K
--------
S
T
S
W
T
------
P
P
G
W
H
--
Q
V
K
-
N
L---
K
G
S
Y
T
H
A
V
D
R
-
G
A
L
L
G
Y
A
L
I
---
G
G
L
D
G
F
D
A
----
S
T
S
N
P
K
N
I
A
V
Q
T
-
A
-
W
A
N
Q
-----
A
Q
-----
A
E
Y
S
T
G
Q
N
Y
Y
E
S
-
K
------
V
R
K
A
L
D
Q
--
N
K
R
V
R
Y
R
V
T
L
Y
Y
A
---
S
N
-----
E
D
L
V
P
S
A
S
Q
I
E
A
K
S
S
D
G
E
---
L
-
E
------------------
F
N
V
L
V
P
N
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
76.01
47%
-35
- C4 -
3OWV
3
NUCE_STRPN
A:
[20-248]
--------------------------------------------------------------------------------------------------------------------------------------------------
S
E
A
P
S
Q
A
L
A
---
E
S
V
L
T
D
A
V
K
S
Q
I
K
G
S
-----
L
E
W
N
-
G
S
G
A
F
I
V
-------
N
G
N
K
T
N
L
D
A
K
V
S
-----
S
K
P
Y
A
D
N
K
T
---
K
---
T
V
G
K
------------
E
T
V
P
T
V
A
N
A
L
L
S
K
A
T
R
Q
Y
-----------
S
W
T
------
P
P
G
W
H
--
Q
V
K
N
L
----
K
G
S
Y
T
H
A
V
D
R
-
G
A
L
L
G
Y
A
L
I
---
G
G
L
D
G
F
D
A
----
S
T
S
N
P
K
N
I
A
V
Q
T
-
A
-
W
A
N
Q
-----
A
Q
-----
A
E
Y
S
T
G
Q
N
Y
Y
E
S
-
K
------
V
R
K
A
L
D
Q
--
N
K
R
V
R
Y
R
V
T
L
Y
Y
A
---
S
N
-----
E
D
L
V
P
S
A
S
Q
I
E
A
K
S
S
D
G
E
---
L
-
E
------------------
F
N
V
L
V
P
N
V
Q
K
G
L
Q
L
D
Y
R
T
G
E
V
T
V
T
Q-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
54.35
26%
-26
* C4 *
2XGR
8
?
A:
[59-250]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Y
Q
L
---
Q
L
--
G
---
E
L
D
N
------------
L
N
R
A
T
F
S
H
I
Q
L
Q
D
R
H
E
T
K
D
V
R
T
-----
K
I
------------------------------
W
V
M
N
R
-
G
H
L
V
G
Y
Q
F
C
---
G
-----------
L
N
D
E
P
R
N
L
V
A
M
T
-
A
-
W
L
N
T
-----
G
A
YSGAN
D
S
N
P
E
G
M
L
Y
Y
E
N
-
R
------
L
D
S
W
L
A
L
H
P
D
F
W
L
D
Y
K
V
T
P
I
Y
S
---
G
N
------
E
V
V
P
R
Q
I
E
L
Q
Y
V
G
I
D
S
S
G
E
L
L
-
T
I
R
LNSNK
E
S
I
D
ENG
V
---
T
T
V
I
L
E
N
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
49.12
24%
-11
- C4 -
2XGR
8
?
A:
[33-250]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
Y
P
N
V
S
H
A
N
T
H
Y
K
-----
N
T
V
S
-
S
K
L
L
P
F
T
-------
A
N
Y
Q
L
Q
L
G
-------------------------
E
L
D
N
------------
L
N
R
A
T
F
S
H
I
Q
L
----------
Q
D
R
H
E
T
K
-
D
V
R
------
T
K
I
W
V
------------------
M
N
R
-
G
H
L
V
G
Y
Q
F
C
---
G
L
N
D
-----------
E
P
R
N
L
V
A
M
T
-
A
-
W
L
N
T
GAYSG
A
N
-----
D
S
N
P
E
G
M
L
Y
Y
E
N
-
R
------
L
D
S
W
L
A
L
H
P
D
F
W
L
D
Y
K
V
T
P
I
Y
S
---
G
N
------
E
V
V
P
R
Q
I
E
L
Q
Y
V
G
I
D
S
S
---
G
-
E
L
L
T
I
R
LNSNK
E
S
I
D
ENG
V
T
T
V
I
L
E
N
S
A
P
N
I
N
L
D
Y
L
N
G
T
A
T
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
40.74
15%
-30
- C4 -
5CQC
1
?
A:
[22-402]
-------------------------------------------------------------------------SIYPPETSWEVNKGMN
S
S
R
L
H
K
L
Y
S
L
F
F
DKSSAFYLGDD
V
S
V
L
L
T
G
--
A
Y
G
F
Q
S
K
K
N
D
Q
Q
I
F
L
F
R
P
DSDY
V
A
G
Y
H
V
D
A
K
S
D
A
GWV
N
D
K
L
D
R
R
L
S
E
I
S
E
F
C
S
K
AT
Q
P
A
T
F
-
I
L
P
F
V
E
M
P
TDITKG
V
Q
H
Q
V
L
L
T
I
S
Y
D
PKSK
Q
L
T
P
T
V
---
Y
---
D
---
S
I
G
R
DTYSESLS
S
Y
F
K
G
K
Y
R
T
T
C
D
E
I
L
T
Q
S
I
E
K
A
I
K
S
T
D
F
T
L
G
K
-------------
F
T
--
R
A
A
-
Y
----
N
T
E
G
N
C
G
S
Y
T
-
F
R
T
I
K
E
V
I
S
---
S
S
A
Q
G
T
T
S
NSYL
T
S
Q
H
V
Q
D
I
E
S
C
I
-
K
-
Y
R
N
L
-----
G
V
-----
V
D
I
E
S
A
L
T
E
G
K
T
-
L
P
VQ
L
S
E
F
I
V
A
L
E
D
--
Y
G
K
L
R
S
Q
Q
Y
S
K
T
A
---
K
L
-----
T
A
V
E
L
L
I
G
I
L
N
D
I
K
G
K
N
E
---
I
S
E
------------------
S
Q
Y
D
K
L
V
K
E
V
D
C
L
M
D
S
S
L
G
K
L
V
Q
F
H
L
K
N
L
GAES
L
Q
K
L
V
LPCVKFD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
39.39
16%
-18
- C4 -
3NKQ
6
ENPP2_MOUSE
A:
[635-702]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
S
Y
-
G
F
L
F
P
P
Y
L
S
---
S
S
P
E
A
K
Y
-----
D
A
F
L
V
T
N
M
V
P
M
Y
-
P
-
A
F
K
R
-----------------
V
W
T
Y
F
Q
R
V
L
------
V
K
K
Y
A
S
E
--
R
N
G
V
N
V
I
S
G
P
I
F
D
---
Y
N
-----
Y
N
G
L
R
D
I
E
D
E
I
K
Q
Y
V
E
G
S
---
S
-
I
------------------
P
V
P
T
H
Y
Y
S
I
I
T
S
C
L
D
F
T
Q
P
A
D
K
C
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
33.67
20%
-11
- C4 -
1ZM8
4
NUCA_NOSS1
A:
[104-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
A
R
-
G
H
I
A
P
S
A
D
R
---
T
K
T
T
E
D
N
A
----
A
T
F
L
M
T
N
M
M
P
Q
T
-
P
-
D
N
N
R
----------------
N
T
W
G
N
L
E
D
-
Y
------
C
R
E
L
V
S
Q
--
G
K
E
L
Y
I
V
A
G
P
N
G
S
---
L
G
KPLKG
K
V
T
V
P
K
S
T
W
K
I
V
V
V
L
D
S
P
---
G
-
S
------------------
G
L
E
G
I
T
A
N
T
R
V
I
A
V
N
I
P
N
D
P
E
L
N
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
32.33
12%
-24
- C2 -
4BHW
5
EP300_HUMAN
A:
[14-576]
------------------------------------------------------------------------------------K
K
I
F
K
P
E
E
L
R
Q
A
L
M
P
T
L
-----------
E
A
L
Y
R
Q
D
PE
S
L
P
F
R
Q
P
V
D
P
Q
L
L
G
I
-------
P
D
Y
F
D
I
V
K
S
P
M
D
---
L
S
T
I
K
R
K
L
D
T
G
Q
Y
Q
E
-----
P
W
Q
Y
-
V
D
D
I
W
L
M
-------
F
N
N
A
W
L
Y
N
R
K
T
S
-----
R
V
Y
K
Y
---
C
---
S
---
K
L
S
E
------------
V
F
E
Q
E
I
D
P
V
M
Q
S
L
---
G
Y
C
C
G
R
K
L
E
F
S
P
Q
T
L
C
------
C
Y
G
K
Q
L
C
T
I
P
-
R
----
D
A
T
Y
Y
S
Y
Q
N
R
-
Y
H
F
C
E
K
C
F
N
E
IQ
G
E
S
V
S
L
G
D
----
D
P
S
Q
P
Q
T
T
I
N
K
E
-
Q
-
F
S
K
R
-----
K
N
-----
D
T
L
D
P
--
E
L
F
V
E
-
C
------
T
E
C
G
R
K
M
--
H
Q
I
C
V
L
H
H
E
I
I
W
P
---
A
G
-----
F
-
V
C
D
G
C
L
K
K
S
A
R
T
R
K
E
N
---
K
-
F
------------------
S
A
K
R
L
P
S
T
R
L
G
T
F
L
E
N
R
V
N
D
F
L
R
R
Q
NHPE
S
G
E
V
T
V
R
V
V
H
A
S
D
K
T
V
E
V
K
P
G
M
K
A
R
FVDSGEMAE
S
F
P
Y
R
T
K
A
L
F
A
F
E
E
I
DG
V
D
L
C
F
F
G
M
H
V
Q
E
Y
G
SDCPPPNQR
R
V
Y
IS
Y
L
D
S
V
HFFRPKCL
R
T
A
V
Y
H
E
I
L
I
G
Y
L
E
Y
V
K
K
L
GYT
T
G
H
I
WACPPSEGDDYIFHCHPPDQ
K
I
P
K
P
K
R
L
Q
E
W
F
K
K
M
L
D
K
A
V
S
E
RIVH
D
Y
K
D
I
F
K
Q
A
T
E
D
RLTSAKE
L
P
Y
F
E
GD
F
W
P
N
V
L
E
E
S
I
K
E
S
GGSGSQK
L
Y
A
T
M
E
K
H
KEV
F
F
V
I
R
LIAGPAANSL
P
P
I
V
D
PD
P
L
I
P
C
DLMDGR
D
A
F
L
T
L
A
R
D
K
HLEFSS
L
R
R
A
Q
W
S
T
M
C
M
L
V
E
L
H
T
Q
S
Q
D
16
HHSearch
31.13
22%
1
- C4 -
3ISM
1
?
A:
[96-164]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
D
R
-
G
H
M
A
A
A
G
N
H
---
R
L
H
Q
K
H
C
D
----
E
T
F
Y
L
S
N
M
A
P
Q
V
G
Q
-
G
F
N
R
----------------
D
A
W
N
T
L
E
A
-
H
------
V
R
R
L
T
K
T
--
Y
S
N
V
Y
V
C
T
G
P
L
Y
L
---
P
H
-----
K
E
D
D
G
K
S
Y
V
K
Y
E
V
I
G
A
N
T
---
V
-
A
------------------
V
P
T
H
F
Y
K
V
I
V
G
E
S
A
D
H
K
L
H
M
E
S
Y
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
30.22
21%
-5
- C4 -
3S5B
1
NUCG_CAEEL
A:
[89-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
R
-
G
H
L
A
A
A
G
N
H
---
R
K
S
Q
L
A
V
D
----
Q
T
F
Y
L
S
N
M
S
P
Q
V
-
G
R
G
F
N
R
----------------
D
K
W
N
D
L
E
M
-
H
------
C
R
R
V
A
K
K
--
M
I
N
S
Y
I
I
T
G
P
L
Y
L
---
P
K
-----
L
E
G
D
G
K
K
Y
I
K
Y
Q
V
I
G
D
N
N
---
V
-
A
------------------
V
P
T
H
F
F
K
V
A
L
F
E
V
T
P
G
K
F
E
L
E
S
Y
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
27.32
19%
-3
- C1 -
2GRG
-
YN034_YEAST
A:
[1-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
S
S
I
P
I
T
E
V
L
-----
P
R
A
V
G
---
S
---
L
---
T
F
D
E
------------
N
Y
N
L
L
D
T
S
G
V
A
K
-
V
I
E
K
S
P
I
A
E
I
I
R
K
S
N
A
E
L
G
------
R
L
G
Y
S
--
V
Y
E
-
D
----
A
Q
Y
I
G
H
A
F
K
K
A
G
H
F
I
V
Y
F
T
P
---
K
N
K
N
R
--
E
----
G
V
V
P
P
V
G
I
T
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
27.06
11%
-26
* C3 *
1YT3
11
RND_ECOLI
A:
[1-375]
M
N
Y
Q
M
I
TT
D
D
A
L
A
S
L
C
E
A
V
RAFP
A
I
A
L
D
T
E
F
V
R
T
RTYYPQLG
L
I
Q
L
F
DGE
H
L
A
L
I
D
PLGITDW
S
P
L
K
A
I
L
R
DPS
I
T
K
F
L
H
AG
S
E
D
L
E
V
F
L
N
V
F
G
E
L
P
Q
P
L
I
-----------
D
T
Q
I
L
A
A
--
F
C
--
G
R
P
-
M
S
W
G
F
A
S
-------
M
V
E
E
Y
S
G
V
T
L
D
K
---
S
E
S
R
T
D
W
L
A
R
P
L
T
E
R
-----
Q
C
E
Y
-
A
A
A
D
V
W
-------------------
Y
-----
L
L
P
I
T
---
A
---
K
---
L
M
V
E
------------
T
E
A
S
G
W
L
P
A
A
L
D
E
C
R
L
M
Q
M
R
R
Q
E
V
V
A
P
E
D
A
W
R
DITNAW
Q
L
R
T
R
--
Q
L
A
-
C
L
Q
L
L
A
D
W
R
L
R
K
A
R
E
-
R
D
L
A
V
N
F
V
V
---
R
E
E
H
L
W
S
V
----
A
R
Y
M
P
G
S
L
G
E
L
D
-
S
-
L
G
L
S
-----
G
S
-----
E
I
R
F
H
G
K
T
L
L
A
L
-
V
------
E
K
A
Q
T
L
P
--
E
D
A
L
P
Q
P
M
L
N
L
M
D
MPG
Y
R
-----
K
A
F
K
A
I
K
S
L
I
T
D
V
S
E
T
H
K
---
I
-
S
------------------
A
E
L
L
A
S
R
R
Q
I
N
Q
L
L
N
W
H
W
K
L
K
P
Q
N
NLPELISG
W
R
G
E
L
M
A
E
A
L
H
N
L
L
Q
EYPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------