@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0673: (2015-12-02 )
MLNQLKNNYFFAVIRGKSSEDALEIAKHAILGGIRNIEVTFSTPEASKVIKQLSDDFKNNKKIIVGAGTVMTTQLAKDAIDAGAKFLVSPHFDSDIANLANENKVYYFPGCATATEIVVARKYKCQIIKLFPGGVVGPDFIKDIHGPIPDVDLMPSGGVSVSNVAEWRKAGAVAVGVGSALSSKVATEGYDSVTKIAKQFVSALD
Atome Classification :
(28 SA)
-------.........10........20........30........40........50......-..60........70........80........90........100...------....110.......120.......130----....-...140......-.-150.......160.......170.-......180-....--..--.--190.......200...-------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------M
L
N
QLKNN
Y
F
F
A
V
I
RGKSS
E
D
A
L
E
I
A
K
H
A
I
LGGI
R
N
I
E
V
T
FSTP
E
A
S
K
V
I
K
Q
L
S
D
D
F-KNN
K
K
I
I
V
GAG
T
V
M
T
T
Q
L
A
K
D
A
I
D
AGA
K
F
L
VSPHFD
S
D
I
A
N
LANEN
K
V
------
Y
Y
FPGCA
T
A
T
E
I
V
V
A
R
K
Y
K
C
Q
I
I
K
LFP----GGVV-
G
P
D
F
I
K
D
I
HGPI-P-DVDLMPSGGV
S
V
S
N
V
A
E
W
R
KAG
A
V
-
A
V
GV
G
S
A
L
S
-
S
K
V
A--TE--G--
Y
D
S
V
T
K
I
A
K
Q
F
V
S
ALD-------------------------------------------------------------------------
22
PsiBlast_CBE
97.78
45%
-132
- C2 -
1WA3
2
?
E:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
1
PsiBlast_PDB
97.73
45%
-128
- C2 -
1WA3
3
?
A:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
2
PsiBlast_PDB
97.44
45%
-129
- C2 -
1VLW
-
?
A:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
23
PsiBlast_CBE
97.27
45%
-128
- C2 -
1WA3
3
?
D:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
21
PsiBlast_CBE
97.10
45%
-131
- C2 -
1WA3
3
?
F:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
24
PsiBlast_CBE
97.08
45%
-130
- C2 -
1WA3
3
?
C:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
25
PsiBlast_CBE
96.65
45%
-127
- C2 -
1WA3
3
?
B:
[3-200]
-------
M
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
--
F
-
L
K
E
K
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
----------
D
E
V
R
E
K
A
K
A
F
V
E
K
I
R
-------------------------------------------------------------------------
48
HHSearch
91.14
47%
-123
- C2 -
1WA3
3
?
A:
[4-185]
--------
E
E
L
F
K
K
H
K
I
V
A
V
L
R
A
N
S
V
E
E
A
K
E
K
A
L
A
V
F
E
G
G
V
H
L
I
E
I
T
F
T
V
P
D
A
D
T
V
I
K
E
L
S
F
L
K
E
K
---
G
A
I
I
G
A
G
T
V
T
S
V
E
Q
C
R
K
A
V
E
S
G
A
E
F
I
V
S
P
H
L
D
E
E
I
S
Q
F
C
K
E
K
G
V
------
F
Y
M
P
G
V
M
T
P
T
E
L
V
K
A
M
K
L
G
H
T
I
L
K
L
F
P
----
G
E
V
V
-
G
P
Q
F
V
K
A
M
K
G
P
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
D
N
V
C
E
W
F
K
A
G
V
L
-
A
V
G
V
G
S
A
L
V
-
K
G
T
P
--
D
E
--
V
--
R
E
K
A
K
A
F
V
E
K
I
R
G
C
---------------------------------------------------------------------------
14
PsiBlast_PDB
86.91
27%
-114
- C2 -
4E38
4
?
A:
[29-231]
---------
N
Q
L
K
A
L
K
V
I
P
V
I
A
I
D
N
A
E
D
I
I
P
L
G
K
V
L
A
E
N
G
L
P
A
A
E
I
T
F
R
S
D
A
A
V
E
A
I
R
L
L
R
----
Q
A
Q
P
E
M
L
I
G
A
G
T
I
L
N
G
E
Q
A
L
A
A
K
E
A
G
A
T
F
V
V
S
P
G
F
N
P
N
T
V
R
A
C
Q
E
I
G
I
------
D
I
V
P
G
V
N
N
P
S
T
V
E
A
A
L
E
M
G
L
T
T
L
K
F
F
P
AEAS
G
G
I
----
S
M
V
K
S
L
V
G
P
Y
-
G
-
D
I
R
L
M
P
T
G
G
I
T
P
S
N
I
D
N
Y
L
A
I
P
Q
V
L
A
C
G
G
T
W
M
V
D
-
K
K
L
V
--
T
N
--
G
E-
W
D
E
I
A
R
L
T
R
E
I
V
E
Q
V
N
-------------------------------------------------------------------------
61
Fugue
84.56
31%
-119
* C2 *
1FQ0
2
ALKH_ECOLI
A:
[1-213]
MKNWKTS
A
E
S
I
L
T
T
G
P
V
V
P
V
I
V
V
K
K
L
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
K
E
V
-
P
E
---
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
----
A
E
A
N
G
G
V
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
A
G
D
--
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
L------------------------------------------------------------------------
44
HHSearch
83.28
31%
-114
- C2 -
1WBH
1
ALKH_ECOLI
A:
[10-212]
--------
E
S
I
L
T
T
G
P
V
V
P
V
I
V
V
K
K
L
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
N
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
K
E
V
-
P
---
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
----
A
E
A
N
G
G
V
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
L
E
A
G
--
D
--
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
42
HHSearch
82.42
27%
-110
- C2 -
1MXS
2
ALKD_PSEPU
A:
[20-223]
--------
D
A
I
C
E
K
A
R
I
L
P
V
I
T
I
A
R
E
E
D
I
L
P
L
A
D
A
L
A
A
G
G
I
R
T
L
E
V
T
L
R
S
Q
H
G
L
K
A
I
Q
V
L
R
E
Q
R
-
P
---
E
L
C
V
G
A
G
T
V
L
D
R
S
M
F
A
A
V
E
A
A
G
A
Q
F
V
V
T
P
G
I
T
E
D
I
L
E
A
G
V
D
S
E
I
------
P
L
L
P
G
I
S
T
P
S
E
I
M
M
G
Y
A
L
G
Y
R
R
F
K
L
F
P
----
A
E
I
S
G
G
V
A
A
I
K
A
F
G
G
P
F
-
G
-
D
I
R
F
C
P
T
G
G
V
N
P
A
N
V
R
N
Y
M
A
L
P
N
V
-
M
C
V
G
T
T
W
M
L
-
D
S
S
W
I
K
N
G
--
D
--
W
A
R
I
E
A
C
S
A
E
A
I
A
L
L
D
-------------------------------------------------------------------------
62
Fugue
82.10
29%
-110
- C2 -
4QCC
-
DGOA_ECOLI
A:
[5-274]
------------
T
K
L
P
L
I
A
I
L
R
G
I
T
P
D
E
A
L
A
H
V
G
A
V
I
D
A
G
F
D
A
V
E
I
P
L
N
S
P
Q
W
E
Q
S
I
P
A
I
V
D
A
Y
-
G
D
--
K
A
L
I
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
G
C
Q
L
I
V
T
P
N
I
H
S
E
V
I
R
R
A
V
G
Y
G
M
------
T
V
C
P
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
A
Q
A
L
K
I
F
P
----
S
S
A
F
-
G
P
Q
Y
I
K
A
L
K
A
V
L
-
P
S
D
I
A
V
F
A
V
G
G
V
T
P
E
N
L
A
Q
W
I
D
A
G
C
A
-
G
A
G
L
G
S
D
L
Y
-
R
--
A
--
G
Q
--
S
--
V
E
R
T
A
Q
Q
A
A
A
F
V
K
A
Y
R
E
A
Q
K
Q
K
E
Q
R
Q
D
Q
K
S
A
Y
A
L
G
A
S
L
G
R
Y
M
E
N
S
L
K
E
Q
E
K
L
GIKLD
K
D
Q
L
I
A
G
V
Q
D
A
F
A
DKSKLS
D
Q
E
I
E
Q
T
L
Q
A
F
E
A
45
HHSearch
81.22
27%
-122
- C2 -
2YW3
2
?
A:
[7-201]
--------
L
A
V
L
A
E
S
R
L
L
P
L
L
T
V
R
G
G
E
D
L
L
G
L
A
R
V
L
E
E
E
G
V
G
A
L
E
I
T
L
R
T
E
K
G
L
E
A
L
K
A
L
R
K
---
S
---
G
L
L
L
G
A
G
T
V
R
S
P
K
E
A
E
A
A
L
E
A
G
A
A
F
L
V
S
P
G
L
L
E
E
V
A
A
L
A
Q
A
R
G
V
------
P
Y
L
P
G
V
L
T
P
T
E
V
E
R
A
L
A
L
G
L
S
A
L
K
F
F
P
----
A
E
P
F
Q
G
V
R
V
L
R
A
Y
A
E
V
F
-
P
-
E
V
R
F
L
P
T
G
G
I
K
E
E
H
L
P
H
Y
A
A
L
P
N
L
-
L
A
V
G
G
S
W
L
L
-
Q
------
G
--
N
--
L
E
A
V
R
A
K
V
R
A
A
K
A
L
L
--------------------------------------------------------------------------
30
PsiBlast_CBE
80.78
32%
-118
- C2 -
1EUA
3
ALKH_ECOLI
C:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
5
PsiBlast_PDB
80.76
29%
-115
- C2 -
2V82
1
DGOA_ECOLI
A:
[9-199]
----------------
L
I
A
I
L
R
G
I
T
P
D
E
A
L
A
H
V
G
A
V
I
D
A
G
F
D
A
V
E
I
P
L
N
S
P
Q
W
E
Q
S
I
P
A
I
V
D
A
Y
-
G
D
--
K
A
L
I
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
G
C
Q
L
I
V
T
P
N
I
H
S
E
V
I
R
R
A
V
G
Y
G
M
------
T
V
C
P
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
A
Q
A
L
K
I
F
P
----
S
S
A
F
-
G
P
Q
Y
I
K
A
L
K
A
V
L
-
P
S
D
I
A
V
F
A
V
G
G
V
T
P
E
N
L
A
Q
W
I
D
A
G
C
A
-
G
A
G
L
G
S
D
L
Y
-
R
--
A
--
G
Q
--
S
--
V
E
R
T
A
Q
Q
A
A
A
F
V
K
A
Y
R
-------------------------------------------------------------------------
49
HHSearch
80.52
29%
-108
- C2 -
2V82
1
DGOA_ECOLI
A:
[3-199]
----------
W
Q
T
K
L
P
L
I
A
I
L
R
G
I
T
P
D
E
A
L
A
H
V
G
A
V
I
D
A
G
F
D
A
V
E
I
P
L
N
S
P
Q
W
E
Q
S
I
P
A
I
V
D
A
Y
-
G
--
D
K
A
L
I
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
G
C
Q
L
I
V
T
P
N
I
H
S
E
V
I
R
R
A
V
G
Y
G
M
------
T
V
C
P
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
A
Q
A
L
K
I
F
P
----
S
S
A
F
-
G
P
Q
Y
I
K
A
L
K
A
V
L
P
S
-
D
I
A
V
F
A
V
G
G
V
T
P
E
N
L
A
Q
W
I
D
A
G
C
A
-
G
A
G
L
G
S
D
L
Y
-
R
A
G
Q
------
S
--
V
E
R
T
A
Q
Q
A
A
A
F
V
K
A
Y
R
-------------------------------------------------------------------------
3
PsiBlast_PDB
80.46
29%
-115
- C2 -
4QCC
-
DGOA_ECOLI
A:
[9-199]
----------------
L
I
A
I
L
R
G
I
T
P
D
E
A
L
A
H
V
G
A
V
I
D
A
G
F
D
A
V
E
I
P
L
N
S
P
Q
W
E
Q
S
I
P
A
I
V
D
A
Y
-
G
D
--
K
A
L
I
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
G
C
Q
L
I
V
T
P
N
I
H
S
E
V
I
R
R
A
V
G
Y
G
M
------
T
V
C
P
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
A
Q
A
L
K
I
F
P
----
S
S
A
F
-
G
P
Q
Y
I
K
A
L
K
A
V
L
-
P
S
D
I
A
V
F
A
V
G
G
V
T
P
E
N
L
A
Q
W
I
D
A
G
C
A
-
G
A
G
L
G
S
D
L
Y
-
R
--
A
--
G
Q
--
S
--
V
E
R
T
A
Q
Q
A
A
A
F
V
K
A
Y
R
-------------------------------------------------------------------------
31
PsiBlast_CBE
80.01
32%
-112
- C2 -
1EUA
3
ALKH_ECOLI
B:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
46
HHSearch
79.87
32%
-108
- C2 -
3VCR
1
?
A:
[12-216]
-------------
T
K
P
L
I
P
V
I
V
I
D
D
L
V
H
A
I
P
M
A
K
A
L
V
A
G
G
V
H
L
L
E
V
T
L
R
T
E
A
G
L
A
A
I
S
A
I
K
K
A
V
-
P
---
E
A
I
V
G
A
G
T
V
C
T
A
D
D
F
Q
K
A
I
D
A
G
A
Q
F
I
V
S
P
G
L
T
P
E
L
I
E
K
A
K
Q
V
K
L
D
GQWQ
G
V
F
L
P
G
V
A
T
A
S
E
V
M
I
A
A
Q
A
G
I
T
Q
L
K
C
F
P
----
A
S
A
I
G
G
A
K
L
L
K
A
W
S
G
P
F
-
P
-
D
I
Q
F
C
P
T
G
G
I
S
K
D
N
Y
K
E
Y
L
G
L
P
N
V
-
I
C
A
G
G
S
W
L
T
-
E
S
K
L
L
I
E
G
--
D
--
W
N
E
V
T
R
R
A
S
E
I
V
K
L
S
D
-------------------------------------------------------------------------
33
PsiBlast_CBE
79.74
32%
-113
- C2 -
1FWR
2
ALKH_ECOLI
B:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
Q
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
K
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
26
PsiBlast_CBE
79.33
32%
-113
- C2 -
1FQ0
2
ALKH_ECOLI
C:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
32
PsiBlast_CBE
78.65
32%
-114
- C2 -
1FWR
2
ALKH_ECOLI
C:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
Q
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
K
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
27
PsiBlast_CBE
78.43
32%
-112
- C2 -
1FQ0
2
ALKH_ECOLI
B:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
10
PsiBlast_PDB
78.38
32%
-112
- C2 -
1FWR
2
ALKH_ECOLI
A:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
Q
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
K
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
7
PsiBlast_PDB
78.36
32%
-114
- C2 -
1FQ0
2
ALKH_ECOLI
A:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
8
PsiBlast_PDB
78.09
32%
-112
- C2 -
1EUA
4
ALKH_ECOLI
A:
[27-208]
--------------------------
E
H
A
V
P
M
A
K
A
L
V
A
G
G
V
R
V
L
E
V
T
L
R
T
E
C
A
V
D
A
I
R
A
I
A
----
K
E
V
P
E
A
I
V
G
A
G
T
V
L
N
P
Q
Q
L
A
E
V
T
E
A
G
A
Q
F
A
I
S
P
G
L
T
E
P
L
L
K
A
A
T
E
G
T
I
------
P
L
I
P
G
I
S
T
V
S
E
L
M
L
G
M
D
Y
G
L
K
E
F
K
F
F
P
AEAN
G
G
V
----
K
A
L
Q
A
I
A
G
P
F
-
S
-
Q
V
R
F
C
P
T
G
G
I
S
P
A
N
Y
R
D
Y
L
A
L
K
S
V
-
L
C
I
G
G
S
W
L
V
-
P
A
D
A
--
L
E
--
A
GD
Y
D
R
I
T
K
L
A
R
E
A
V
E
G
A
K
-------------------------------------------------------------------------
6
PsiBlast_PDB
77.19
34%
-107
- C2 -
3VCR
1
?
A:
[27-216]
----------------------------
A
I
P
M
A
K
A
L
V
A
G
G
V
H
L
L
E
V
T
L
R
T
E
A
G
L
A
A
I
S
A
I
K
----
K
A
V
P
E
A
I
V
G
A
G
T
V
C
T
A
D
D
F
Q
K
A
I
D
A
G
A
Q
F
I
V
S
P
G
L
T
P
E
L
I
E
K
A
K
Q
V
K
L
D
GQWQ
G
V
F
L
P
G
V
A
T
A
S
E
V
M
I
A
A
Q
A
G
I
T
Q
L
K
C
F
P
----
A
S
A
I
G
G
A
K
L
L
K
A
W
S
G
P
F
-
P
-
D
I
Q
F
C
P
T
G
G
I
S
K
D
N
Y
K
E
Y
L
G
L
P
N
V
-
I
C
A
G
G
S
W
L
T
E
S
K
L
L
--
I
E
--
G
D-
W
N
E
V
T
R
R
A
S
E
I
V
K
L
S
D
-------------------------------------------------------------------------