@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0749: (2015-12-02 )
MGLFDRLFGHKKKDKEPEIEASESVVLEDEDSVIDKEEGSNFSKESTLNRTSEVPVAEDDSFLELERDTALSESHQPVTSEIHPLESEDTDEIPVKEDDSFLELEDRAKTKVADTSEVENVVPDSTTLSDNVSAKSEASFSDKEQLSDSQASDQFSETPLQEEMSSGKTEVQTESEDTSAADAFLADYYAKRKAIEKEISSNSLSTDESEFSEAQEVLSQSQADTIKAESQEEKYNRSLKKTRTGFSARLNAFLSNFRRVDEEFFEELEEMLILSDVGVNVATQLTEDLRYEAKLENAKKSEDLKRVIVEKLVEIYEKDGIYNEAINFQEGLTVMLFVGVNGVGKTTSIGKLAHQYKSQGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVVTGEEKADPASVVFDGMEKAVAQGVDVLLIDTAGRLQNKENLMAELEKIGRIIKRVVPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKIDDIGEFNSEDFMRGLLEGIL
Atome Classification :
(48 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250----------.......-.---.260.----.....----.270.......280.......290....----..---.----300---.......-------.310.......----320.----..--.-..-----.-330-...------.------....340.......350.....-..360.......370.......380-----...---....390...-....400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
G
L
F
D
R
L
FGHKKKDKEPEIEAS
E
S
V
V
LEDEDSVI
D
K
E
EGSNFSKESTLNRTSEVPVAEDDS
F
L
E
LERDTALSESHQPVTSEIHPLESEDTDEIPVKEDD
S
F
L
E
L
E
D
RAKTKVA
D
T
S
E
V
E
NVVPDSTTLSDNVSAKSEASFS
D
K
E
QLSDSQASDQFSET
P
L
Q
E
E
M
SSGK
T
E
V
Q
TESEDT
S
A
A
D
A
F
L
A
D
Y
Y
A
K
R
K
A
I
E
K
E
ISSNSLST
D
E
S
E
F
S
E
A
Q
E
V
L
S
QSQADTIKA
E
S
Q
E
E
K
Y
N
R
S
L
K
K
TRT
G
F
S
A
R
L
------------
N
A
F
L
S
N
F
-
R
---
R
V
D
E
E
----
F
F
E
E
L
----
E
E
M
L
I
L
SDVG
V
N
V
A
T
Q
L
T
E
D
L
R
Y
E
A
KLE----NA---
K
----
K
S
----
E
D
L
K
R
V
I
-------
V
E
K
L
V
E
I
Y
E
KD----GIYN----EA--I-NF-----Q-E-G-
L
T
V
------
M
------
L
F
V
GVNGVGKT
T
S
I
G
K
L
A
H
Q
Y
K-SQG
K
K
V
M
L
V
A
ADTFRA
G
A
V
A
Q
L
V
E
W-----GRR---VDVPVVTGEE-KAD
P
A
S
V
V
F
D
G
M
E
K
A
V
AQGV
D
V
L
L
IDTAGRLQ
N
K
E
N
L
M
A
E
L
E
K
I
G
R
I
I
K
R
VVPDAPH
E
T
L
L
A
L
DAST
G
Q
N
A
L
S
Q
A
K
E
F
SKITPL
T
G
L
I
L
T
KIDGTAKG
G
V
V
L
A
I
R
QELDI
P
V
K
F
IGFGEKI
D
D
IGEF
N
S
E
D
F
M
R
G
L
L
E
GIL
3
PsiBlast_PDB
95.42
47%
-114
- C5 -
2YHS
5
FTSY_ECOLI
A:
[189-493]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
KTKENLG
S
G
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I
S
L
F
-
R
GK-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
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P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
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E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
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I
A
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K
K
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M
K
K
L
D
V
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M
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A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--
1
PsiBlast_PDB
94.64
45%
-110
- C5 -
1ZU4
1
FTSY_MYCMS
A:
[9-313]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
M
L
K
S
A
F
N
F
S
K
D
I
------------
K
K
L
S
K
K
Y
-
K
---
Q
A
D
D
E
----
F
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
K
T
K
R
D
----
T
S
---------
F
----
E
N
I
K
D
A
L
-------
V
E
S
L
Y
Q
A
Y
T
D
N
----
D
W
--------YR
I
-
D
F
-----
K
-
E
-
N
R
L
N
I
------
F
------
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
-
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
T
RL
N
N
K
---
V
D
L
-
V
K
A
N
K
L
-
N
A
D
P
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
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K
S
A
P
H
E
V
L
L
V
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A
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Q
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E
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F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
Q
Y
I
V
H
L
S
S
G
F
M
4
PsiBlast_PDB
94.47
47%
-106
- C5 -
2QY9
-
FTSY_ECOLI
A:
[198-493]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
R
S
L
L
K
T
K
E
N
L
G
---------------
S
G
F
I
S
L
F
-
R
GK-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
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A
P
H
E
V
M
L
T
I
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A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--
6
PsiBlast_PDB
94.06
47%
-108
- C5 -
1FTS
-
FTSY_ECOLI
A:
[201-493]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
L
K
T
K
E
N
L
G
---------------
S
G
F
I
S
L
F
-
R
GK-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
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L
Q
N
K
S
H
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M
E
E
L
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R
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M
K
K
L
D
V
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A
P
H
E
V
M
L
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I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
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L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
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V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--
2
PsiBlast_PDB
93.61
45%
-108
- C5 -
1ZU5
-
FTSY_MYCMS
A:
[100-404]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
M
L
K
S
A
F
N
F
S
K
D
I
------------
K
K
L
S
K
K
Y
-
K
---
Q
A
D
D
E
----
F
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
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K
V
S
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R
K
K
T
K
R
D
----
T
S
---------
F
----
E
N
I
K
D
A
L
-------
V
E
S
L
Y
Q
A
Y
T
D
N
----
D
W
T
N
----
K
K
YR
I
-
D
F
-----
K
-
E
-
N
R
L
N
I
------
F
------
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
-
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
TRL
N
N
K
---
V
D
L
-
V
K
A
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N
A
D
P
A
S
V
V
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A
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L
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M
104
HHSearch
93.30
48%
-98
- C5 -
1VMA
1
?
A:
[13-305]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
L
F
D
F
L
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R
V
------------
V
K
L
L
K
G
--
K
---
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L
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D
E
----
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R
E
E
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E
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I
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E
E
K
D
G
-----------------------
D
A
L
E
S
L
-------
K
E
I
I
L
E
I
L
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F
D
-------
T
----
K
---
L
-
N
V
-----
P
-
P
E
P
-
P
F
V
------
I
------
M
V
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G
V
N
G
T
G
K
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C
G
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A
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A
A
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I
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Q
L
K
I
W
-----
G
E
R
---
V
G
A
T
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
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A
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A
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A
L
A
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N
K
D
V
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A
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N
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E
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R
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R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
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V
T
G
I
I
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T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
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I
K
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E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
--
99
HHSearch
93.26
46%
-101
- C5 -
2YHS
5
FTSY_ECOLI
A:
[189-495]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
------------
I
S
L
F
R
G
--
K
---
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
V
-------
D
----
E
P
--
L
-
N
V
-----
E
-
G
K
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--
23
PsiBlast_CBE
92.94
48%
-100
- C5 -
1VMA
1
?
B:
[19-304]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
------------
V
K
L
L
K
G
--
K
---
K
L
D
D
E
----
T
R
E
E
L
----
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
--
R
L
E
E
K
------
D
G
---
D
----
A
L
----
E
S
L
K
E
I
I
-------
L
E
I
L
N
------------
F
D
----
T
K
--
L
-
N
V
-----
P
P
E
-
P
-
P
F
V
------
I
------
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
-
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
-----
G
E
R
---
V
G
A
T
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
--
7
PsiBlast_PDB
92.74
47%
-109
- C5 -
3ZN8
-
FTSY_ECOLI
D:
[1-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
L
K
T
K
E
N
L
G
---------------
S
G
F
I
S
L
F
-
R
GK-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--
112
HHSearch
92.32
50%
-109
- C5 -
1ZU4
1
FTSY_MYCMS
A:
[31-312]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
D
D
E
----
F
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
K
T
K
R
D
---------
T
----
S
F
----
E
N
I
K
D
A
L
-------
V
E
S
L
Y
Q
A
Y
T
D
N
----
D
W
------
Y
R
--
I
-
D
F
-----
K
-
E
N
R
-
L
N
I
------
F
------
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
-
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
-----
I
K
T
RLN
N
K
V
D
L
V
K
A
N
K
L
N
A
D
P
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
Q
Y
I
V
H
L
S
S
G
F
M
22
PsiBlast_CBE
92.09
48%
-110
- C5 -
4C7O
5
FTSY_ECOLI
D:
[2-274]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
-
9
PsiBlast_PDB
91.97
48%
-99
- C5 -
1VMA
1
?
A:
[19-304]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
------------
V
K
L
L
K
G
--
K
---
K
L
D
D
E
----
T
R
E
E
L
----
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
--
R
L
E
E
K
------
D
G
---
D
----
A
L
----
E
S
L
K
E
I
I
-------
L
E
I
L
N
------------
F
D
----
T
K
--
L
-
N
V
-----
P
P
E
-
P
-
P
F
V
------
I
------
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
-
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
-----
G
E
R
---
V
G
A
T
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
--
8
PsiBlast_PDB
91.43
48%
-105
- C5 -
4C7O
4
FTSY_ECOLI
B:
[5-274]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
---
21
PsiBlast_CBE
90.45
47%
-110
- C5 -
2XXA
3
FTSY_ECOLI
D:
[20-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
F
-
R
GK-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
D
5
PsiBlast_PDB
90.31
47%
-108
- C5 -
2XXA
3
FTSY_ECOLI
B:
[20-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
F
-
R
G
K
-
K
I
D
D
D
----
L
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
---
R
----
D
A
----
E
A
L
Y
G
L
L
-------
K
E
E
M
G
E
I
L
A
K
-------
V
D
----
E
P
--
L
-
N
V
-----
E
G
K
-
A
-
P
F
V
------
I
------
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-----
G
Q
R
---
N
N
I
P
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
D
100
HHSearch
90.26
39%
-109
- C5 -
3B9Q
1
CFTSY_ARATH
A:
[1-302]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
------------
D
E
L
L
L
F
W
-
N
L--
A
E
T
D
R
----
V
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
L
---
K
----
S
G
----
S
E
I
K
D
A
L
-------
K
E
S
V
L
E
M
L
A
K
------
S
K
T
----
E
---
L
-
Q
L
-----
G
-
F
R
K
-
P
A
V
------
I
------
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
-
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-----
A
E
R
---
T
G
C
E
I
V
V
A
E
--
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
---
98
HHSearch
87.92
39%
-102
- C5 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
------------
D
E
L
L
L
F
W
N
L
---
A
E
T
D
R
----
V
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
L
---
K
----
S
G
----
S
E
I
K
D
A
L
-------
K
E
S
V
L
E
M
L
A
K
K
-------
T
----
E
---
L
-
Q
L
-----
G
-
F
R
K
-
P
A
V
------
I
------
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
-
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-----
A
E
R
---
T
G
C
E
I
V
V
A
E
G
D
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
---
17
PsiBlast_PDB
87.39
45%
-107
- C5 -
1OKK
8
FTSY_THEAQ
D:
[42-302]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
---------------------------------
P
V
EPKGRV
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
19
PsiBlast_PDB
86.98
45%
-104
- C5 -
2J7P
7
FTSY_THEAQ
D:
[22-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
--------------------------------
K
P
V
EPKG
R
V
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
29
PsiBlast_CBE
86.91
45%
-103
- C5 -
2J7P
9
FTSY_THEAQ
E:
[22-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
---------------------------------
P
V
EPKGRV
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
113
HHSearch
85.96
44%
-99
- C5 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
E
E
----
V
L
E
E
L
----
E
M
A
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----------------------
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
D
----
E
R
R
A
T
L
R
K
L
G
--
F
-
N
P
Q
KPKP
V
E
P
-
K
-
G
R
V
------
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
30
PsiBlast_CBE
85.52
45%
-100
- C5 -
1RJ9
3
FTSY_THEAQ
A:
[43-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
----
L
G
--
F
-
N
P
-----
Q
-
K
-
P
-
K
P
V
EPKGR
V
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
16
PsiBlast_PDB
85.04
45%
-111
- C5 -
2IYL
3
FTSY_THEAQ
D:
[23-283]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
D
A---
T
L
R
K
----
L
G
--
F
-
N
P
-----
Q
-
K
----
P
V
EPKGRV
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
--
14
PsiBlast_PDB
84.56
45%
-95
- C5 -
2Q9C
8
FTSY_THEAQ
A:
[43-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
----
L
G
--
F
-
N
P
-----
Q
-
K
-
P
-
K
P
V
EPKGR
V
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
--
13
PsiBlast_PDB
84.49
45%
-96
- C5 -
2Q9B
12
FTSY_THEAQ
A:
[43-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----------
A
---
S
----
G
R
----
K
D
L
K
E
A
V
-------
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
----
L
G
--
F
-
N
P
-----
Q
-
K
-
P
-
K
P
V
EPKGR
V
V
------
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-----
G
K
R
---
L
S
I
P
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---
48
PsiBlast_CBE
80.47
37%
-93
- C5 -
1NG1
13
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
40
PsiBlast_CBE
80.43
37%
-95
- C5 -
3NG1
7
SRP54_THEAQ
B:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
DLKA
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KDRNLW
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
41
PsiBlast_CBE
80.01
37%
-95
- C5 -
3NG1
6
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
39
PsiBlast_CBE
80.01
37%
-90
- C5 -
1JPJ
1
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
42
PsiBlast_CBE
79.74
37%
-88
- C5 -
2J7P
8
SRP54_THEAQ
B:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
47
PsiBlast_CBE
79.69
37%
-87
- C5 -
1OKK
17
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
---
53
PsiBlast_CBE
79.65
37%
-91
- C5 -
1O87
7
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-
109
HHSearch
79.62
33%
-80
- C5 -
3DM5
10
SRP54_PYRFU
A:
[3-297]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
--------------
S
S
V
D
---
E
---
A
L
I
K
E
----
L
V
R
D
I
----
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
KPPA
G
I
---
S
----
K
K
----
E
H
I
I
K
I
V
-------
Y
E
E
L
T
K
F
L
G
T
E
-------
A
----
K
P
--
I
-
E
------
I
-
K
E
K
-
P
T
I
------
L
------
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
-
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-----
L
D
R
---
Y
H
I
E
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
52
PsiBlast_CBE
79.41
37%
-87
- C5 -
1O87
7
SRP54_THEAQ
B:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
DLKA
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KDRNLW
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-
37
PsiBlast_CBE
79.09
37%
-90
- C5 -
1JPN
4
SRP54_THEAQ
B:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
DLKA
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KDRNLW
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-
43
PsiBlast_CBE
79.08
37%
-89
- C5 -
2J7P
11
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
38
PsiBlast_CBE
78.79
37%
-91
- C5 -
1JPN
4
SRP54_THEAQ
A:
[5-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
35
PsiBlast_CBE
78.58
35%
-100
- C5 -
3DM5
9
SRP54_PYRFU
B:
[23-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
E
A
----
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
----
K
P
---
P
AGIS
K
K
----
E
H
I
I
K
I
V
-------
Y
E
E
L
T
K
F
L
-------
G
T
E
A
----
K
P
--
I
-
E
I
-----
K
-
E
-
K
-
P
T
I
------
L
------
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
-
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-----
L
D
R
---
Y
H
I
E
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
67
PsiBlast_CBE
78.54
33%
-95
- C5 -
4C7O
5
SRP54_ECOLI
C:
[31-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
V
----
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
V
---
N
----
K
S
LT
P
G
Q
E
F
V
K
I
V
-------
R
N
E
L
V
A
A
M
-------
G
E
E
N
----
Q
T
--
L
-
N
L
-----
A
A
Q
-
P
-
P
A
V
------
V
------
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
-----
A
E
Q
---
V
G
V
D
F
F
P
S
D
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
-
68
PsiBlast_CBE
78.52
33%
-97
- C5 -
4C7O
4
SRP54_ECOLI
A:
[31-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
V
----
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
V
---
N
----
K
S
LT
P
G
Q
E
F
V
K
I
V
-------
R
N
E
L
V
A
A
M
-------
G
E
E
N
----
Q
T
--
L
-
N
L
-----
A
A
Q
-
P
-
P
A
V
------
V
------
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
-----
A
E
Q
---
V
G
V
D
F
F
P
S
D
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
---
36
PsiBlast_CBE
77.89
35%
-95
- C5 -
3DM5
10
SRP54_PYRFU
A:
[23-294]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
E
A
----
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
----
K
P
---
P
AGIS
K
K
----
E
H
I
I
K
I
V
-------
Y
E
E
L
T
K
F
L
-------
G
T
E
A
----
K
P
--
I
-
E
I
-----
K
-
E
-
K
-
P
T
I
------
L
------
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
-
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-----
L
D
R
---
Y
H
I
E
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
59
PsiBlast_CBE
77.36
36%
-93
- C5 -
2NG1
4
SRP54_THEAQ
A:
[4-286]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
R
L
------------
Q
E
A
I
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--
106
HHSearch
76.12
36%
-91
- C5 -
3E70
3
?
C:
[50-324]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
V
D
K
----
A
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
RIG------
G
----
K
I
I
E
E
A
V
-------
K
E
A
V
S
E
I
L
E
T
S
----
R
R
I
D
----
L
I
--
E
E
I
R
-----
K
-
A
E
K
-
P
Y
V
------
I
------
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-----
A
K
R
---
I
G
V
K
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
------
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---
33
PsiBlast_CBE
75.20
37%
-93
- C5 -
3DMD
4
?
B:
[56-319]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
---
R
----
I
G
----
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
----
D
L
I
E
----
E
---
I
-
R
K
-----
A
-
E
-
K
-
P
Y
V
------
I
------
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-----
A
K
R
---
I
G
V
K
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---
32
PsiBlast_CBE
74.78
37%
-94
- C5 -
3DMD
7
?
C:
[56-319]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
---
R
----
I
G
----
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
----
D
L
I
E
----
E
---
I
-
R
K
-----
A
-
E
-
K
-
P
Y
V
------
I
------
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-----
A
K
R
---
I
G
V
K
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---
34
PsiBlast_CBE
74.72
37%
-95
- C5 -
3DMD
6
?
A:
[56-319]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
---
R
----
I
G
----
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
----
D
L
I
E
----
E
---
I
-
R
K
-----
A
-
E
-
K
-
P
Y
V
------
I
------
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-----
A
K
R
---
I
G
V
K
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---
31
PsiBlast_CBE
74.50
37%
-92
- C5 -
3E70
3
?
C:
[56-319]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
---
R
----
I
G
-------
G
K
I
I
EEAVKEA
V
S
E
I
L
E
T
S
R
R
I
----
D
L
I
E
----
E
---
I
-
R
K
-----
A
-
E
-
K
-
P
Y
V
------
I
------
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-----
A
K
R
---
I
G
V
K
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---
60
PsiBlast_CBE
74.38
36%
-82
- C5 -
1RJ9
3
SRP54_THEAQ
B:
[14-287]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
L
-
R
GRG
R
I
T
E
E
D
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
---
L
----
E
S
----
L
T
P
A
E
V
I
----------
L
A
T
V
Y
E
A
-------
L
K
----
E
A
--
L
-
G
G
-----
E
-
A
-
R
-
L
P
V
------
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-----
G
E
K
---
V
G
V
P
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-