@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0769: (2015-12-03 )
MAFSPIKKLLQDIKSGKMVVLMDDENRENEGDLICAAEMVTKESINFMAKFGKGLICLPLSNYYAEKLELAQMASHNTDNHETAFTISIDHLSTSTGISAEDRALTAKMVANDSSKAKDFRRPGHLFPLLAKEGGVLARNGHTEATVDLCRLAGLKECGLCCEIMAEDGSMMRKDELLAFAQKHDLAIATIKQLQDYRRQEEGGVVREIEIQLPTQFGHFTAYGYSEVVANKEHVALVKGDISSGEDVLCRLHSECLTGDVFHSLRCDCGEQLANALQQIEAEGRGVLLYMRQEGRGIGLINKLKAYHLQEEGLDTLEANLALGFEGDERDYGVSAQLLKDLGINSINLLTNNPDKIQQLEAEGICVKNRVPLQVAATAYDLNYLKTKKEKMGHLLD
Atome Classification :
(34 SA)
.........---10........20........30........40........50........60.......------.70......----------------..------------80........90-..--.-......100.......110-------...------.....120.......130.......140.......150.......160...-----------.-.--.-----------.------------170.......180.......190.......200.......210.......220.......230.......240..-.....250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
F
S
P
I
K
K
L
---
L
Q
D
I
KSG
K
M
V
V
L
MDDENRENEG
D
L
I
C
A
A
E
M
V
T
K
E
S
I
N
F
M
A
K
FGK
G
L
I
C
L
P
L
S
N
Y
Y
A
E
K
L
------
E
L
A
Q
M
ASHN----------------TD------------NH
E
T
A
F
T
I
S
I
D
--HL--S-TSTGISAEDR
A
L
T
A
K
M
VA--------NDS------
S
K
A
K
D
FRRPGH
L
F
P
L
L
AKEG
G
V
L
ARNGH
T
E
A
T
V
D
L
C
R
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-----------A-E--D-----------G------------SM
M
R
K
D
E
L
L
A
F
A
Q
KH
D
L
A
I
A
T
I
K
Q
L
Q
D
Y
R
R
QEEG
G
V
V
R
E
I
E
I
Q
LPTQFGH
F
T
AY
G
Y
S
E
V
VANK
E
H
V
A
L
V
KGDISS-
G
E
D
V
L
C
R
L
H
S
E
CL
T
G
D
V
F
H
S
L
R
C
D
C
G
E
Q
L
A
N
A
L
Q
Q
I
E
AEG
R
G
V
L
L
Y
M
RQEGRGI
G
L
I
N
K
L
K
A
Y
H
L
Q
E
EGL
D
T
L
E
A
N
L
A
LGFEGDERDY
G
V
S
A
Q
L
L
K
D
LGI
N
S
I
N
L
LTNN
P
D
K
I
Q
Q
LEAE
G
I
C
VKNRV
P
L
Q
V
A
A
T
A
Y
D
L
N
Y
L
K
T
K
K
E
KMGHLLD
1
PsiBlast_PDB
96.01
51%
-109
- C7 -
4I14
2
RIBBA_MYCTA
A:
[7-383]
-----
V
E
R
A
---
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
------
G
L
L
P
M
Y
-------------------------------------
A
Y
T
V
T
V
D
--
A
R
--
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
--------
D
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-----------
S
-
Q
KD
E
-----------
G
------------
S
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
K
H
I
E
R
V
A
E
A
R
I
P
T
R
H
G
E
F
R
A
I
G
Y
T
S
I
Y
E
D
V
E
H
V
A
L
V
R
G
E
I
A
G
D
G
D
D
V
L
V
R
V
H
S
E
C
L
T
G
D
V
F
G
S
R
R
C
D
C
G
P
Q
L
D
A
A
L
A
M
V
A
R
E
G
R
G
V
V
L
Y
M
R
---------------------------------------
Y
G
I
G
A
Q
I
L
V
D
L
G
V
R
S
M
R
L
L
T
N
N
P
------
D
G
Y
G
L
H
I
I
E
R
V
P
L
P
-----------------------
15
PsiBlast_PDB
76.88
46%
-98
- C7 -
1K4P
7
RIB3_MAGO7
A:
[12-225]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-------------
D
--
D
-----------
G
QEVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
75.67
46%
-101
- C7 -
1K49
4
RIB3_MAGO7
A:
[12-225]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
-----------------------------------
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-------------
D
--
D
-----------
G
QEVEGRAVRAAP
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
75.45
46%
-97
- C7 -
1K4L
4
RIB3_MAGO7
A:
[12-225]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-------------
D
--
D
-----------
G
QEVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
74.91
46%
-99
- C7 -
1K4I
4
RIB3_MAGO7
A:
[12-225]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-------------
D
--
D
-----------
G
QEVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.66
58%
-109
- C7 -
4FFJ
8
?
A:
[1-199]
M
E
Y
R
K
I
Q
E
A
---
L
E
A
L
Q
K
G
R
L
V
L
V
I
D
D
K
D
--
N
E
G
D
L
I
C
S
A
Q
A
A
T
T
E
N
V
N
F
M
A
T
Y
A
K
G
L
I
C
M
P
M
S
E
S
L
A
N
Q
L
------
M
L
S
P
M
V
E
-----------------------------------
T
A
F
T
V
S
I
D
--
Y
K
--
E
-
T
T
T
G
I
S
A
E
E
R
G
L
T
A
R
M
C
V
--------
A
E
D
------
I
T
P
S
D
F
R
R
P
G
H
M
F
P
L
I
A
K
K
G
G
V
L
E
R
N
G
H
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-----------
N
-
H
--
D
-----------
G
------------
K
M
M
R
T
D
D
L
I
Q
F
S
K
K
H
N
I
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
74.52
46%
-98
- C7 -
1K4O
4
RIB3_MAGO7
A:
[12-225]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-------------
D
--
D
-----------
G
QEVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Fugue
74.16
47%
-99
- C7 -
1K4I
4
RIB3_MAGO7
A:
[12-227]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
--
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
DDGQEVEGRAV
R
-
A
--
A
-----------
P
------------
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
74.03
42%
-97
- C7 -
3LS6
8
RIBB_SALTY
A:
[13-211]
--
F
E
R
V
E
L
A
---
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
------
D
L
P
M
M
V
E
N
N
----------------
T
S
------------
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E-
G
-
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
--------
K
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-----------
N
-
D
--
D
-----------
G
------------
T
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
73.20
46%
-98
- C7 -
1K4I
4
RIB3_MAGO7
A:
[12-227]
--
F
D
A
I
P
D
V
---
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
------
D
L
P
Q
M
V
T
H
N
----------------
A
D
------------
P
R
G
T
A
Y
T
V
S
V
D
--
A
E
HP
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
--------
A
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-----------
D
-
D
--
G
QEVEGRAVRAA
P
------------
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
V
E
K
T
E
G
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
72.87
48%
-104
- C7 -
3MIO
6
RIBBA_MYCTA
B:
[7-206]
-----
V
E
R
A
---
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
------
G
L
L
P
M
----------------------------------------
T
V
T
V
D
--
A
R
--
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
--------
D
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-----------
S
-
Q
KD
E
-----------
G
------------
S
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.75
48%
-107
- C7 -
3MK5
5
RIBBA_MYCTA
A:
[13-212]
-----
V
E
R
A
---
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
---
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
------
G
L
L
P
M
Y
---------------------------------------
T
V
T
V
D
--
A
R
--
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
--------
D
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-----------
S
--D-
E
-----------
G
------------
S
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
72.60
48%
-108
- C7 -
2RIU
1
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
---
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
------
E
L
P
P
M
L
A
----------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E-
G
-
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
--------
N
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-----------
R
D
E
--
D
-----------
G
------------
L
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
72.21
48%
-105
- C7 -
3MIO
5
RIBBA_MYCTA
A:
[7-206]
-----
V
E
R
A
---
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
------
G
L
L
P
M
Y
---------------------------------------
T
V
T
V
D
--
A
R
--
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
--------
D
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-----------
S
-
Q
KD
E
-----------
G
------------
S
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
72.20
48%
-107
- C7 -
1TKS
-
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
---
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
------
E
L
P
P
M
L
A
----------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E-
G
-
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
--------
N
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-----------
R
D
E
--
D
-----------
G
------------
L
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
72.12
48%
-103
- C7 -
3MIO
5
RIBBA_MYCTA
A:
[3-204]
-
R
L
D
S
V
E
R
A
---
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
------
G
L
L
P
M
Y
---------------------------------------
T
V
T
V
D
--
A
R
N-
G
-
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
--------
D
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-----------
S
-
Q
KD
E
-----------
G
------------
S
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
72.02
48%
-108
- C7 -
1TKU
1
RIB3_CANAL
B:
[5-201]
--
F
T
P
I
E
E
A
---
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
------
E
L
P
P
M
L
A
----------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E-
G
-
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
--------
N
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-----------
R
D
E
--
D
-----------
G
------------
L
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.97
48%
-109
- C7 -
2RIS
-
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
---
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
------
E
L
P
P
M
L
A
----------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E-
G
-
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
--------
N
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-----------
R
D
E
--
D
-----------
G
------------
L
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
71.66
42%
-104
- C7 -
3LRJ
2
RIBB_SALTY
C:
[13-212]
--
F
E
R
V
E
L
A
---
L
D
A
L
R
E
G
R
G
V
M
V
L
D
------
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
------
D
L
P
M
M
V
E
N
N
----------------
T
S
------------
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E-
G
-
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
--------
K
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-----------
N
-
D
--
D
-----------
G
------------
T
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
71.64
42%
-100
- C7 -
3LQU
1
RIBB_SALTY
B:
[13-212]
--
F
E
R
V
E
L
A
---
L
D
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
------
D
L
P
M
M
V
E
N
N
----------------
T
S
------------
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E-
G
-
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
--------
K
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-----------
N
-
D
--
D
-----------
G
------------
T
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
71.33
48%
-107
- C7 -
1TKU
1
RIB3_CANAL
A:
[5-201]
--
F
T
P
I
E
E
A
---
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
------
E
L
P
P
M
L
A
----------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E-
G
-
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
--------
N
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-----------
R
D
E
--
D
-----------
G
------------
L
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
70.98
42%
-99
- C7 -
3LQU
1
RIBB_SALTY
A:
[13-212]
--
F
E
R
V
E
L
A
---
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
------
D
L
P
M
M
V
E
N
N
----------------
T
S
------------
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E-
G
-
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
--------
K
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-----------
N
-
D
--
D
-----------
G
------------
T
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
Q
A
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
70.27
44%
-98
- C7 -
4P6P
9
RIBB_VIBCH
B:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A
-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
69.37
44%
-96
- C7 -
4P8E
13
RIBB_VIBCH
B:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A
-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
68.90
44%
-100
- C7 -
4P6P
5
RIBB_VIBCH
A:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
68.65
44%
-99
- C7 -
4P8E
7
RIBB_VIBCH
A:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
68.64
44%
-100
- C7 -
4P6D
2
RIBB_VIBCH
A:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
-----------------------------------------
T
V
S
I
E
A
-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
68.43
44%
-99
- C7 -
4P77
2
RIBB_VIBCH
B:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
-----------------------------------
T
A
F
T
V
S
I
E
A
-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
67.94
44%
-96
- C7 -
4P6C
2
RIBB_VIBCH
B:
[33-232]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A
-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
67.86
44%
-95
- C7 -
4P77
3
RIBB_VIBCH
A:
[32-231]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
--------------
N
Q
T
A
F
T
V
S
I
E
A-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
66.95
44%
-94
- C7 -
4P6C
2
RIBB_VIBCH
A:
[33-232]
----
P
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
------
A
L
P
P
M
V
V
N
N
----------------
N
S
------------
A
N
Q
T
A
F
T
V
S
I
E
A-
K
H
--
G
-
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
--------
N
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-----------
N
-
P
--
D
-----------
G
------------
S
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
D
L
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
64.79
35%
-87
- C7 -
1SNN
6
RIBB_METJA
A:
[2-220]
---
N
N
V
E
K
A
---
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
------
G
I
P
F
M
V
D
I
L
E
F
A
SQKF
K
V
L
R
E
L
YPN
D
I
PY----------
D
E
K
S
S
F
S
I
T
I
N
--
H
R
--
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
--------
E
L
V
K
E
GRFN
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-----------
G
-
D
--
D
-----------
G
------------
N
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
62.38
33%
-97
- C7 -
1SNN
3
RIBB_METJA
B:
[4-219]
-----
V
E
K
A
---
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
GIPF
M
V
D
I
L
E
F
A
S
Q
K
----------------
F
K
V
L
R
E
L
YPNDIPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
--
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GRF
N
D
F
--------
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-----------
G
-
D
--
D
-----------
G
------------
N
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
Y
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
62.24
33%
-100
- C7 -
1PVY
3
RIBB_METJA
B:
[4-219]
-----
V
E
K
A
---
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
GIPF
M
V
D
I
L
E
F
A
S
Q
K
----------------
F
K
V
L
R
E
L
YPNDIPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
--
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GRF
N
D
F
--------
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-----------
G
-
D
--
D
-----------
G
------------
N
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
Y
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------