@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : gbs0898: (2015-12-04 )
MAFDVIMPKLGVDMQEGEILEWKKNEGDTVNEGDVLLEIMSDKTNMEIEAEDTGVLLKIVHQAGDVVPVTEVIAYIGEEGEEVGTSSPSADATITAEDGQSVSGPAAPSQETVAAATPKEELAADEYDIVVVGGGPAGYYAAIRGAQLGGKIAIVEKTEFGGTCLNVGCIPTKTYLKNAEILDGLKVAAGRGINLASTNYAIDMDKTVAFKNSVVKTLTGGVRGLLKANKVEIFNGLGQVNPDKSVVIGDKVIKGRNVVLATGSKVSRINIPGIESPLVLTSDDILDLREIPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAMDKEVSLELQKILAKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVADKALLSIGRVPQMNGLENLEPELEMERGRIKVNAYQETSIPGIYAPGDVNGTRMLAHAAYRMGEVAAENALGGNKRKAHLDFTPAAVYTHPEVAMVGMTEEQAREQYGDILVGKNSFTGNGRAIASNEAHGFVKVIAEPKYKEILGVHIIGPAAAELINEASTIMENELTVYDVAQSIHGHPTFSEVMYEAFLDVLGEAIHNPPKRK

Atome Classification :

(30 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.....-------.-------.-160.......170....----...180-.----.----..-.--.-.-.---190------.......-.200.......210.......220.......230.......-240....--..-----.-----------250.........260.......270..--..----...----.280.......-290........300.......310.......320.......-330.......340...-....350-........360..---.--...-------.--370---.-----.----.---.----.--.-.---..380...-----....390--.......-400-.-.-.-.-....410.......420.....-..430........440.......450----.........460--....----....470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580...
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MAFDVIMPKLGVDMQEGEILEWKKNEGDTVNEGDVLLEIMSDKTNMEIEAEDTGVLLKIVHQAGDVVPVTEVIAYIGEEGEEVGTSSPSADATITAEDGQSVSGPAAPSQETVAAATPKEELAADEYDIVVVGGGPAGYYAAIRGAQLGGKIAIVEK-------T-------E-FGGTCLNVGCIPTKTYL----KNAEI--L----D----GL-K--V-A-A---GR-------GINLAST-NYAIDMDKTVAFKNSVVKTLTGGVRGLLKANKVEIFNGLGQ-VNPDKSV--VI-----G-----------D--KVIKGRNVVLATGSKVSRIN-IPG--IE----SPL----VLTSDDILDLR-E-IPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIP-AMDKEVSLELQKILAK-KGMKIK--TSVGVSEIVEANN---Q--LTL-------K--L-----N-----N----G---E----E--V-V---ADKALLSI-----GRVPQMN--GLENLEP-E-L-E-M-E-R-GRIKVNAYQETSIPGIYAPGDV-NGT-RMLAHAAYRMGEVAAENALG------GNKRKAHLDF-T--PAAV----YTHPEVAMVGMTEEQAREQYGDILVGKNSFTGNGRAIASNEAHGFVKVIAEPKYKEILGVHIIGPAAAELINEASTIMENELTVYDVAQSIHGHPTFSEVMYEAFLDVLGEAIHNPPKRK
104 HHSearch 91.4243% -92 - C3 -2EQ6 ? A:[4-458] ---------------------------------------------------------------------------------------------------------------------------MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEA-------G-------E-VGGVCLNVGCIPTKALL----HAAET--L----H----HL-K--V-A-E---GF-------GLKA----KPELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFAR-LVGPKEV--EV-----G-----------G--ERYGAKSLILATGSEPLELKGFPF--------GED----VWDSTRALKVEEG-LPKRLLVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILP-QGDPETAALLRRALEK-EGIRVR--TKTKAVGYEKKKD---G--LHV-------R--LEPAEGG-----E----G---E----E--V-V---VDKVLVAV-----GRKPRTE--GLG-LEK-AGV-KVD-E-R-GFIRVNARMETSVPGVYAIGDA-ARP-PLLAHKAMREGLIAAENAAG------KDS-AFDY-Q-V--PSVV----YTSPEWAGVGLTEEEAKRAGYKVKVGKFPLAASGRALTLGGAEGMVKVVGDEETDLLLGVFIVGPQAGELIAEAALALEMGATLTDLALTVHPHPTLSESLMEAAEAFHKQAIHILN---
21 PsiBlast_CBE 91.0840% -89 - C3 -3LAD DLDH_AZOVI B:[1-472] ---------------------------------------------------------------------------------------------------------------------------SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKT-------A-LGGTCLNVGCIPSKALLDSSYKFHEA--H----E----SF-K--L--------H-------GIS--TG-EVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK-LLAGKKV--EVTAADGS-----------S--QVLDTENVILASGSKPVEIP-PAP--VD----QDV----IVDSTGALDFQ-N-VPGKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLP-AVDEQVAKEAQKILTK-QGLKIL--LGARVTGTEVKNK---Q--VTV-------K--F-----V-----D----A---EGEK-S--Q-A---FDKLIVAV-----GRRPVTT--DLLAADS-G-V-T-LDE-R-GFIYVDDYCATSVPGVYAIGDV-VRG-AMLAHKASEEGVVVAER-IA------GHKAQMNYDL-I--PAVI----YTHPEIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIHVA----
103 HHSearch 90.7042% -92 - C3 -3LAD DLDH_AZOVI A:[1-472] ---------------------------------------------------------------------------------------------------------------------------SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIEK-------YKGKEGKTA-LGGTCLNVGCIPSKALL----DSSYK--F----H----EA-HE-S-F-K---LH-------GISTG---EVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK-LLAGKKV--EV-----TAADGS------S--QVLDTENVILASGSKPVEIP-PAP--VD----QDV----IVDSTGALDFQ-N-VPGKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLP-AVDEQVAKEAQKILTK-QGLKIL--LGARVTGTEVKNK---Q--VTV-------K--F-----V-----DAEG-E---K----S--Q-A---FDKLIVAV-----GRRPVTT--DLL-AAD-SGV-TLD-E-R-GFIYVDDYCATSVPGVYAIGDV-VRG-AMLAHKASEEGVVVAERIAG------HKA-QMNYDL-I--PAVI----YTHPEIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIHVA----
14 PsiBlast_PDB 90.6540% -93 - C3 -1EBD DLDH1_GEOSE A:[1-450] ---------------------------------------------------------------------------------------------------------------------------AIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEK-------G-------N-LGGVCLNVGCIPSKALI----SASHR--Y----E----QA-K--H-S-E---EM-------GIK--AE-NVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAY-FVDANTVRVVN-----G-----------DSAQTYTFKNAIIATGSR--PIE-LPN--FKF---SNR----ILDSTGALNLG-E-VPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILS-GFEKQMAAIIKKRLKK-KGVEVV--TNALAKGAEERED---G--VTV-------T--Y-----EA----N----G---E----TKTI-D---ADYVLVTV-----GRRPNTDELGLEQIGI-K-M---T-N-R-GLIEVDQQCRTSVPNIFAIGDI-VPG-PALAHKASYEGKVAAE-AIA------GHPSAVDYVA-I--PAVV----FSDPECASVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVAL-----------
1 PsiBlast_PDB 90.5340% -94 - C3 -3LAD DLDH_AZOVI A:[1-472] ---------------------------------------------------------------------------------------------------------------------------SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKT-------A-LGGTCLNVGCIPSKALLDSSYKFHEA--H----E----SF-K--L--------H-------GIS--TG-EVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK-LLAGKKV--EVTAADGS-----------S--QVLDTENVILASGSKPVEIP-PAP--VD----QDV----IVDSTGALDFQ-N-VPGKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLP-AVDEQVAKEAQKILTK-QGLKIL--LGARVTGTEVKNK---Q--VTV-------K--F-----V-----D----A---EGEK-S--Q-A---FDKLIVAV-----GRRPVTT--DLLAADS-G-V-T-LDE-R-GFIYVDDYCATSVPGVYAIGDV-VRG-AMLAHKASEEGVVVAER-IA------GHKAQMNYDL-I--PAVI----YTHPEIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIHVA----
114 HHSearch 90.5040% -96 - C3 -1EBD DLDH1_GEOSE A:[2-455] ----------------------------------------------------------------------------------------------------------------------------IETETLVVGAGPGGYVAAIRAAQLGQKVTIVEK-------G-------N-LGGVCLNVGCIPSKALI----SASHR--Y----E----QA-K--H-S-E---EM-------GIKAE---NVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAY-FVDANTV--RV-----VNGDS-------A--QTYTFKNAIIATGSRPIELP-NFK--F-----SNR----ILDSTGALNLG-E-VPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILS-GFEKQMAAIIKKRLKK-KGVEVV--TNALAKGAEERED---G--VTV-------T--Y-----EA----N----GET-K----T--I-D---ADYVLVTV-----GRRPNTD--ELG-LEQ-IGI-KMT-N-R-GLIEVDQQCRTSVPNIFAIGDI-VPG-PALAHKASYEGKVAAEAIAG------HPS-AVDYVA-I--PAVV----FSDPECASVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVAL-----------
72 PsiBlast_CBE 89.3440% -93 - C3 -1EBD DLDH1_GEOSE B:[1-450] ---------------------------------------------------------------------------------------------------------------------------AIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEK-------G-------N-LGGVCLNVGCIPSKALI----SASHR--Y----E----QA-K--H-S-E---EM-------GIK--AE-NVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAY-FVDANTVRVVN-----G-----------DSAQTYTFKNAIIATGSR--PIE-LPN--FKF---SNR----ILDSTGALNLG-E-VPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILS-GFEKQMAAIIKKRLKK-KGVEVV--TNALAKGAEERED---G--VTV-------T--Y-----EA----N----G---E----TKTI-D---ADYVLVTV-----GRRPNTDELGLEQIGI-K-M---T-N-R-GLIEVDQQCRTSVPNIFAIGDI-VPG-PALAHKASYEGKVAAE-AIA------GHPSAVDYVA-I--PAVV----FSDPECASVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVAL-----------
102 HHSearch 89.2840% -95 * C3 *3URH ? A:[26-486] ------------------------------------------------------------------------------------------------------------------------------YDLIVIGSGPGGYVCAIKAAQLGMKVAVVEK-------RS------T-YGGTCLNVGCIPSKALL----HASEM--F----H----QA-Q--HGL-E---AL-------GVEVA---NPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGK-VLGQGKV--SV-----TNEKGE------E--QVLEAKNVVIATGSDVAG---IPG--VEVAFDEKT----IVSSTGALALE-K-VPASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILG-GMDGEVAKQLQRMLTK-QGIDFK--LGAKVTGAVKSGD---G--AKV-------T--F-----EPVKGGE----A---T----T--L-D---AEVVLIAT-----GRKPSTD--GLG-LAK-AGV-VLD-S-R-GRVEIDRHFQTSIAGVYAIGDV-VRG-PMLAHKAEDEGVAVAEIIAG------QAG-HVNYDV-I--PGVV----YTQPEVASVGKTEEELKAAGVAYKIGKFPFTANGRARAMLQTDGFVKILADKETDRVLGGHIIGFGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAVKEAALSTFF----------
17 PsiBlast_PDB 88.4738% -96 - C3 -3URH ? A:[26-486] ------------------------------------------------------------------------------------------------------------------------------YDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKR------S-------T-YGGTCLNVGCIPSKALL----HASEM--F----HQAQHGL-E--A-L--------------GVEVA---NPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGK-VLGQGKV--SV-----TNEKGE------E--QVLEAKNVVIATGSDVA--G-IPG--VE----VAFDEKTIVSSTGALALE-K-VPASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILG-GMDGEVAKQLQRMLTK-QGIDFK--LGAKVTGAVKSGDGA-K--VTF-------E--P-----V-----K----G---G----E--A-TTLDAEVVLIAT-----GRKPSTD--GLGLAKA-G-V-V-L-DSR-GRVEIDRHFQTSIAGVYAIGDV-VRG-PMLAHKAEDEG-VAVAEIIA------GQAGHVNYDV-I--PGVV----YTQPEVASVGKTEEELKAAGVAYKIGKFPFTANGRARAMLQTDGFVKILADKETDRVLGGHIIGFGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAVKEAALSTFF----------
99 HHSearch 88.2740% -89 - C3 -2QAE DLDH_TRYCR A:[1-464] ----------------------------------------------------------------------------------------------------------------------------NPYDVVVIGGGPGGYVASIKAAQLGMKTACVEK-------RG------A-LGGTCLNVGCIPSKALL----HATHL--Y----H----DA-H--ANF-A---RY-------GLMGG-E-GVTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYYKGEGS-FETAHSI--RV-----NGLDGK------Q--EMLETKKTIIATGSEPTELP-FLP--FD----EKV----VLSSTGALALP-R-VPKTMVVIGGGVIGLELGSVWARLGAEVTVVEFAPRCAP-TLDEDVTNALVGALAKNEKMKFM--TSTKVVGGTNNGD---S--VSLEV-----E-------------------GKR-E----T--V-T---CEALLVSV-----GRRPFTG--GLG-LDK-INV-AKN-E-R-GFVKIGDHFETSIPDVYAIGDV-VDKGPMLAHKAEDEGVACAEILAG------KPG-HVNYGV-I--PAVI----YTMPEVASVGKSEDELKKEGVAYKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRILGVHIVCTTAGELIGEACLAMEYGASSEDVGRTCHAHPTMSEALKEACMALFAKTINF-----
13 PsiBlast_PDB 88.0940% -88 - C3 -1DXL DLDH_PEA A:[4-469] ---------------------------------------------------------------------------------------------------------------------------SDENDVVIIGGGPGGYVAAIKAAQLGFKTTCIEK-------RG------A-LGGTCLNVGCIPSKALL----HSSHM--Y----H----EA-K--H-SFA---NH-------GVKV--S-NVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGKFVSPSEIS--VD-----TIEGE-------N--TVVKGKHIIIATGSDVK--S-LPGVTID----EKK----IVSSTGALALS-E-IPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVP-TMDAEIRKQFQRSLEK-QGMKFK--LKTKVVGVDTSGD---G--VKL-------T--V-----EPSA--G----G---E----Q--T-IIE-ADVVLVSA-----GRTPFTS--GLNLDKI-G-V-E-T-D-KLGRILVNERFSTNVSGVYAIGDV-IPG-PMLAHKAEEDG-VACVEYLA------GKVGHVDYDK-V--PGVV----YTNPEVASVGKTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHIMAPNAGELIHEAAIALQYDASSEDIARVCHAHPTMSEAIKEAAMATYDKPIHI-----
112 HHSearch 87.7439% -94 - C3 -2YQU ? A:[1-452] -----------------------------------------------------------------------------------------------------------------------------MYDLLVIGAGPGGYVAAIRAAQLGMKVGVVEK-------EK------A-LGGTCLRVGCIPSKALL----ETTER--I----Y----EA-K--K-G-----LL-------GAKVK---GVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTAR-FLSERKV--LVEE---T-----------G--EELEARYILIATGSAPLIPP-WAQ--VD----YER----VVTSTEALSFP-E-VPKRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRILP-TMDLEVSRAAERVFKK-QGLTIR--TGVRVTAVVPEAK---G--ARV-------E--L-----E-----G----G---E----V--L-E---ADRVLVAV-----GRRPYTE--GLS-LEN-AGL-STD-E-R-GRIPVDEHLRTRVPHIYAIGDV-VRG-PMLAHKASEEGIAAVEHMVR------GFG-HVDYQA-I--PSVV----YTHPEIAAVGYTEEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEILKEAALAAWERPIHL-----
100 HHSearch 87.4939% -90 - C3 -1ZMD DLDH_HUMAN A:[3-470] --------------------------------------------------------------------------------------------------------------------------QPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEK-------NE------T-LGGTCLNVGCIPSKALL----NNSHY--Y----H----MA-HGTD-F-A---SR-------GIEMS---EVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGK-ITGKNQV--TA-----TKADGG------T--QVIDTKNILIATGSEVTPFP-GIT--ID----EDT----IVSSTGALSLK-K-VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQK-QGFKFK--LNTKVTGATKKSDG--K--IDV-------SIEA-----A-----S----GGKAE----V--I-T---CDVLLVCI-----GRRPFTK--NLG-LEE-LGI-ELD-P-R-GRIPVNTRFQTKIPNIYAIGDV-VAG-PMLAHKAEDEGIICVEGMAG------GAV-HIDYNC-V--PSVI----YTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF----
5 PsiBlast_PDB 87.3738% -96 - C3 -2YQU ? A:[2-454] ------------------------------------------------------------------------------------------------------------------------------YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEK-------E-------KALGGTCLRVGCIPSKALL----ETTER--IYEAKK----GL-L--G-A-K---VK-------GVEL--------DLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTAR-FLSERKV--LV-----E-----------ETGEELEARYILIATGSAPLIPP-WAQ--VD----YER----VVTSTEALSFP-E-VPKRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRILP-TMDLEVSRAAERVFKK-QGLTIR--TGVRVTAVVPEAK---G--ARV-------E--L-----E-----G----G---E----V--L-E---ADRVLVAV-----GRRPYTE--GLSLENA-G-L-S-TDE-R-GRIPVDEHLRTRVPHIYAIGDV-VRG-PMLAHKASEEGIAAVEHMVR------GF---GHVDY-QAIPSVV----YTHPEIAAVGYTEEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEILKEAALAAWERPIHL-----
109 HHSearch 87.3040% -92 - C3 -1DXL DLDH_PEA A:[4-467] ---------------------------------------------------------------------------------------------------------------------------SDENDVVIIGGGPGGYVAAIKAAQLGFKTTCIEK-------RG------A-LGGTCLNVGCIPSKALL----HSSHM--Y----H----EA-K--HSF-A---NH-------GVKVS---NVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGK-FVSPSEI--SV-----DTIEGE------N--TVVKGKHIIIATGSDVKSLP-GVT--ID----EKK----IVSSTGALALS-E-IPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVP-TMDAEIRKQFQRSLEK-QGMKFK--LKTKVVGVDTSGD---G--VKL-------T--V-----EPSAGGE----Q---T----I--I-E---ADVVLVSA-----GRTPFTS--GLN-LDK-IGV-ETD-K-L-GRILVNERFSTNVSGVYAIGDV-IPG-PMLAHKAEEDGVACVEYLAG------KVG-HVDYDK-V--PGVV----YTNPEVASVGKTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHIMAPNAGELIHEAAIALQYDASSEDIARVCHAHPTMSEAIKEAAMATYDKPIHI-----
32 PsiBlast_CBE 87.2438% -95 - C3 -2YQU ? B:[2-454] ------------------------------------------------------------------------------------------------------------------------------YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEK-------E-------KALGGTCLRVGCIPSKALL----ETTER--IYEAKK----GL-L--G-A-K---VK-------GVEL--------DLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTAR-FLSERKV--LV-----E-----------ETGEELEARYILIATGSAPLIPP-WAQ--VD----YER----VVTSTEALSFP-E-VPKRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRILP-TMDLEVSRAAERVFKK-QGLTIR--TGVRVTAVVPEAK---G--ARV-------E--L-----E-----G----G---E----V--L-E---ADRVLVAV-----GRRPYTE--GLSLENA-G-L-S-TDE-R-GRIPVDEHLRTRVPHIYAIGDV-VRG-PMLAHKASEEGIAAVEHMVR------GF---GHVDY-QAIPSVV----YTHPEIAAVGYTEEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEILKEAALAAWERPIHL-----
26 PsiBlast_CBE 86.9539% -96 - C3 -1ZY8 DLDH_HUMAN G:[8-464] -------------------------------------------------------------------------------------------------------------------------------DVTVIGSGPGGYVAAIKAAQLGFKTVCIEK-------N-------ETLGGTCLNVGCIPSKALL----NNSHYYHM----A----HG-K--D-F-A---SR-------GIEMSEV-R--LNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGK-ITGKNQV--TATKADGG-----------T--QVIDTKNILIATGSEVTPFP-GIT--ID----EDT----IVSSTGALSLK-K-VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQK-QGFKFK--LNTKVTGATKKSDGKID--VSI-------E--A-----A-----S----GGKAE----V--I-T---CDVLLVCI-----GRRPFTKNLGLEELGI-E-L-D---P-R-GRIPVNTRFQTKIPNIYAIGDV-VAG-PMLAHKAEDEGIICVEGMAG------G---AVHIDY-NCVPSVI----YTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF----
15 PsiBlast_PDB 86.9337% -92 - C3 -1JEH DLDH_YEAST A:[6-477] ------------------------------------------------------------------------------------------------------------------------------HDVVIIGGGPAGYVAAIKAAQLGFNTACVEK-------RG------K-LGGTCLNVGCIPSKALL----NNSHL--F----H----QM-H--TEA-Q---KR-------GIDV-NG-DIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGS-FEDETKI--RV-----TPVDGLEGTVKED--HILDVKNIIVATGSEVTPF---PG--IEID--EEK----IVSSTGALSLK-E-IPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGA-SMDGEVAKATQKFLKK-QGLDFK--LSTKVISAKRNDD---K--NVVEIVVEDTK--T-----N-----K----Q---E----N--L-E---AEVLLVAV-----GRRPYIA--GLGAEKI-G-L-E-V-DKR-GRLVIDDQFNSKFPHIKVVGDV-TFG-PMLAHKAEEEGIAAVEMLKT------GH---GHVNY-NNIPSVM----YSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC-----
33 PsiBlast_CBE 86.9138% -97 - C3 -2EQ7 ? B:[2-452] ------------------------------------------------------------------------------------------------------------------------------YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEK-------E-------KALGGTCLRVGCIPSKALL----ETTER--IYEAKK----GL-L--G-A-K---VK-------GVEL--------DLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTAR-FLSERKV--LV-----E-----------ETGEELEARYILIATGSAPLIPP-WAQ--VD----YER----VVTSTEALSFP-E-VPKRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRILP-TMDLEVSRAAERVFKK-QGLTIR--TGVRVTAVVPEAK---G--ARV-------E--L-----E-----G----G---E----V--L-E---ADRVLVAV-----GRRPYTE--GLSLENA-G-L-S-TDE-R-GRIPVDEHLRTRVPHIYAIGDV-VRG-PMLAHKASEEGIAAVEHMVR------GF---GHVDY-QAIPSVV----YTHPEIAAVGYTEEELKAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHGIGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEILKEAALAAWERP--------
106 HHSearch 86.7638% -90 - C3 -1V59 DLDH_YEAST A:[2-474] --------------------------------------------------------------------------------------------------------------------------INKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEK-------RG------K-LGGTCLNVGCIPSKALL----NNSHL--F----H----QM-HT-E-A-Q---KR-------GIDVNG--DIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGS-FEDETKI--RV-----TPVDGLEGTVKED--HILDVKNIIVATGSEVTPFP-GIE--ID----EEK----IVSSTGALSLK-E-IPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGA-SMDGEVAKATQKFLKK-QGLDFK--LSTKVISAKRNDD---KNVVEI-------V--V-----EDTKTNK----Q---E----N--L-E---AEVLLVAV-----GRRPYIA--GLG-AEK-IGL-EVD-K-R-GRLVIDDQFNSKFPHIKVVGDV-TFG-PMLAHKAEEEGIAAVEMLKT------GHG-HVNYNN-I--PSVM----YSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC-----
96 HHSearch 86.1035% -93 - C3 -1LVL DLDH1_PSEPU A:[2-455] --------------------------------------------------------------------------------------------------------------------------QTIQTTLLIIGGGPGGYVAAIRAGQLGIPTVLVEG-------Q-------A-LGGTCLNIGCIPSKALI----HVAEQ--F----H----QA-S--R-F-TEPSPL-------GISVA---SPRLDIGQSVAWKDGIVDRLTTGVAALLKKHGVKVVHGWAK-VLDGKQV--EV-----D-----------G--QRIQCEHLLLATGSSSVELP-MLP--LG-----GP----VISSTEALAPK-A-LPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERILP-TYDSELTAPVAESLKK-LGIALH--LGHSVEGYENG-----C----L-------L--A-----N-----DGKGGQ---L----R--L-E---ADRVLVAV-----GRRPRTK--GFN-LEC-LDL-KMN---G-AAIAIDERCQTSMHNVWAIGDV-AGE-PMLAHRAMAQGEMVAEIIAG------KAR-RFEPAA-I--AAVC----FTDPEVVVVGKTPEQASQQGLDCIVAQFPFAANGRAMSLESKSGFVRV