@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0899: (2015-12-04 )
MKYIVNTSNDPAYNVALEAYAFQKLTDIDEIFILWINEPAIIIGRHQNTIQEINKEFIDKNGIHVVRRLSGGGAVYHDLNNLNYTIISNNTQEGAFDFQTFSKPVIDTLAKLGVKAEFTGRNDLEINGQKFAGNAQAYYKGRMMHHGCLLFDVDMSVLGQALKVSKDKIESKGIKSVRARVTNIVDHLSDKITVQEFSDAILAQMKEEYPEMDEYVLSDAELSEIQAMRDNQFATWDWTYGKAPEYTIERGVRYPAGKITTYANVENSTIKSVKIFGDFFGVKPVDDIEKMLEGVRYDYKDVLAALKTVDTSQYFSRMTPEEITKAIVD
Atome Classification :
(20 SA)
.........10........20.....--...30........40........50-........60........70........80.-.....-..90.--.......100.......110--......-.-120--------......----------..---.-130.......140.......150.......160.......170.......180.......190.......200......-.210.-.---...----...---220........230-........240.......250...--....260.......270.......-280..-.....290.......300.......310.......320.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
Y
I
V
NTSNDP
A
Y
N
V
A
L
E
A
Y
A
F
Q
KLT--DI
D
E
I
F
I
L
W
INE
P
A
I
I
I
GRH
Q
N
T
I
Q
-
E
I
N
K
E
F
IDKNG
I
H
V
V
R
RLSGG
G
A
V
Y
H
DLNNL-
N
Y
T
I
I-SNNTQ--EG
A
F
D
F
Q
TFS
K
P
V
I
D
T
L
A
KL--G
V
K
A
E
F-T-G----------RN
D
L
E
I----------NG---Q-KFAGNAQ
A
Y
YKGRMMHH
G
C
L
L
F
DV
D
M
S
V
L
G
Q
A
L
K
V
S
K
D
K
I
E
SK
G
I
K
S
V
R
A
R
V
T
N
I
V
D
H
LSDK
I
T
V
Q
E
F
S
D
A
I
L
A
Q
M
K
E
E-YP
E
-
M
-
D
---
E
Y
V
----LSD---
A
E
-
L
S
E
I
Q
A
M
RDN--Q
F
A
T
W
DWTYGKAP
E
Y
T
I
E
RGVRYP--AG
K
I
T
T
Y
A
NVENS
T
I
K
S
V
K
I
F
G
DF-FGVK
P
-
V
D
D
I
E
K
M
L
E
GVRY
D
Y
K
D
V
L
A
A
L
K
TV
D
T
S
Q
Y
F
S
RM
T
P
E
E
I
T
K
A
IVD
41
HHSearch
99.52
64%
-103
- C3 -
1VQZ
18
?
A:
[13-340]
M
K
Y
I
I
N
H
S
N
D
T
A
F
N
I
A
L
E
E
Y
A
F
K
H
L
L
--
D
E
D
Q
I
F
L
L
W
I
N
K
P
S
I
I
V
G
R
H
Q
N
T
I
E
-
E
I
N
R
D
Y
V
R
E
N
G
I
E
V
V
R
R
I
S
G
G
G
A
V
Y
H
D
L
N
N
L
-
N
Y
T
I
I
-
S
K
E
D
E
--
N
K
A
F
D
F
K
S
F
S
T
P
V
I
N
T
L
A
Q
L
--
G
V
K
A
E
F
-
T
-
G
----------
R
N
D
L
E
I
----------
D
G
---
K
-
K
F
C
G
N
A
Q
A
Y
I
N
G
R
I
M
H
H
G
C
L
L
F
D
V
D
L
S
V
L
A
N
A
L
K
V
S
K
D
K
F
E
S
K
G
V
K
S
V
R
A
R
V
T
N
I
I
N
E
L
P
K
K
I
T
V
E
K
F
R
D
L
L
L
E
Y
M
K
K
E
-
Y
P
E
-
M
-
T
---
E
Y
V
----
F
S
E
---
E
E
-
L
A
E
I
N
R
I
K
D
T
--
K
F
G
T
W
D
W
N
Y
G
K
S
P
E
F
N
V
R
R
G
I
K
F
T
--
S
G
K
V
E
V
F
A
N
V
T
E
S
K
I
Q
D
I
K
I
Y
G
D
F
-
F
G
I
E
D
-
V
A
A
V
E
D
V
L
R
G
V
K
Y
E
R
E
D
V
L
K
A
L
K
T
I
D
I
T
R
Y
F
A
G
I
S
R
E
E
I
A
E
A
V
V
G
1
PsiBlast_PDB
98.43
62%
-102
- C3 -
1VQZ
18
?
A:
[14-340]
-
K
Y
I
I
N
H
S
N
D
T
A
F
N
I
A
L
E
E
Y
A
F
K
H
L
L
--
D
E
D
Q
I
F
L
L
W
I
N
K
P
S
I
I
V
G
R
H
Q
N
T
I
E
-
E
I
N
R
D
Y
V
R
E
N
G
I
E
V
V
R
R
I
S
G
G
G
A
V
Y
H
D
L
N
N
L
-
N
Y
T
I
I
-
S
K
E
D
E
--
N
K
A
F
D
F
K
S
F
S
T
P
V
I
N
T
L
A
Q
L
--
G
V
K
A
E
F
-
T
-
G
----------
R
N
D
L
E
I
----------
D
G
---
K
-
K
F
C
G
N
A
Q
A
Y
I
N
G
R
I
M
H
H
G
C
L
L
F
D
V
D
L
S
V
L
A
N
A
L
K
V
S
K
D
K
F
E
S
K
G
V
K
S
V
R
A
R
V
T
N
I
I
N
E
L
P
K
K
I
T
V
E
K
F
R
D
L
L
L
E
Y
M
K
K
E
-
Y
P
E
-
M
-
T
---
E
Y
V
----
F
S
E
---
E
E
-
L
A
E
I
N
R
I
K
D
T
--
K
F
G
T
W
D
W
N
Y
G
K
S
P
E
F
N
V
R
R
G
I
K
F
T
--
S
G
K
V
E
V
F
A
N
V
T
E
S
K
I
Q
D
I
K
I
Y
G
D
F
-
F
G
I
E
D
-
V
A
A
V
E
D
V
L
R
G
V
K
Y
E
R
E
D
V
L
K
A
L
K
T
I
D
I
T
R
Y
F
A
G
I
S
R
E
E
I
A
E
A
V
V
G
42
HHSearch
77.27
29%
-87
* C3 *
3A7R
6
LPLA_ECOLI
A:
[3-334]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
E
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
F
H
H
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
G
I
T
S
V
R
S
R
V
T
N
L
T
E
L
L
P
-
G
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
-
R
V
E
---
A
E
I
----
I
S
P
NKT
P
D
-
L
P
N
F
A
E
T
F
A
R
---
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
2
PsiBlast_PDB
75.75
30%
-86
- C3 -
3A7A
2
LPLA_ECOLI
A:
[3-302]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
E
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
F
H
H
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
G
I
T
S
V
R
S
R
V
T
N
L
T
E
L
L
P
G
-
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
R
V
-
E
---
A
E
I
----
I
S
P
---
N
K
-
T
P
D
L
P
N
F
A
E
T
F
A
R
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
3
PsiBlast_PDB
75.13
30%
-85
- C3 -
3A7R
5
LPLA_ECOLI
A:
[3-302]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
E
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
F
H
H
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
G
I
T
S
V
R
S
R
V
T
N
L
T
E
L
L
P
G
-
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
R
V
-
E
---
A
E
I
----
I
S
P
---
N
K
-
T
P
D
L
P
N
F
A
E
T
F
A
R
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
6
PsiBlast_PDB
74.16
29%
-83
- C3 -
4TVW
1
LPLA_ECOLI
A:
[7-306]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
A
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
A
H
G
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
G
I
T
S
V
R
S
R
V
T
N
L
T
E
L
L
P
G
-
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
R
V
-
E
---
A
E
I
----
I
S
P
---
N
K
-
T
P
D
L
P
N
F
A
E
T
F
A
R
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
43
HHSearch
73.66
24%
-86
- C3 -
2E5A
5
LIPT_BOVIN
A:
[5-341]
G
L
I
L
Q
S
I
S
N
D
V
Y
H
N
L
A
V
E
D
W
I
H
D
H
M
N
L-
E
G
K
P
V
L
F
L
W
R
N
S
P
T
V
V
I
G
R
H
Q
N
P
W
Q
-
E
C
N
L
N
L
M
R
E
E
G
V
K
L
A
R
R
R
S
G
G
G
T
V
Y
H
D
M
G
N
I
-
N
L
T
F
F
-
T
T
K
K
K
-----
Y
D
R
M
E
N
L
K
L
V
V
R
A
L
K
A
V
H
P
H
L
D
V
Q
A
-
T
-
K
----------
R
F
D
L
L
L
----------
D
G
Q--
F
-
K
I
S
G
T
A
S
K
I
G
R
N
A
A
Y
H
H
C
T
L
L
C
G
T
D
G
T
F
L
S
S
L
L
K
S
P
Y
Q
G
I
R
S
N
A
T
A
S
T
P
A
L
V
K
N
L
M
E
K
D
P
-
T
L
T
C
E
V
V
I
N
A
V
A
T
E
Y
A
T
S
-
H
Q
I
-
D
-
N
H
I
H
L
I
N
----
P
T
D
---
E
T
V
F
P
G
I
N
S
K
A
I
E
---
L
Q
T
W
E
W
I
Y
G
K
T
P
K
F
S
V
D
T
S
F
T
V
L
HS
H
V
E
I
K
V
F
I
D
V
K
N
G
R
I
E
V
C
N
I
E
A
P
D
H
W
L
P
L
E
I
C
D
Q
L
N
S
S
L
I
G
S
K
F
S
P
I
E
T
T
V
-------------
D
E
L
H
S
K
W
N
I
L
C
E
5
PsiBlast_PDB
72.49
30%
-83
- C3 -
1X2H
1
LPLA_ECOLI
A:
[3-302]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
E
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
F
H
H
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
-------
R
V
T
N
L
T
E
L
L
P
G
-
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
R
V
-
E
---
A
E
I
----
I
S
P
---
N
K
-
T
P
D
L
P
N
F
A
E
T
F
A
R
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
44
HHSearch
70.17
27%
-91
- C3 -
2C8M
1
LPLAN_THEAC
A:
[4-256]
R
L
L
L
L
E
T
P
G
N
T
R
M
S
L
A
Y
D
E
A
I
Y
R
S
F
Q
Y-
G
D
K
P
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
-
R
S
S
D
D
M-
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
LNDVSIPVNK
K
T
D
I
M
A
----------
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
---------------
E
R
V
A
N
V
T
D
F
V
--
D
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
-
L
H
I
-
D
F
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
-------------------------------------------------------------------------------------------
14
PsiBlast_PDB
64.53
29%
-94
- C3 -
2ARS
1
LPLAN_THEAC
A:
[35-255]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
PVNKKTDIMA
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
------------
K
S
T
R
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
L
------------------------------------------------------------------------------------------
13
PsiBlast_PDB
64.18
29%
-101
- C3 -
2C8M
1
LPLAN_THEAC
A:
[35-255]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
PVNKKTDIMA
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
---------------
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
-------------------------------------------------------------------------------------------
7
PsiBlast_PDB
64.15
28%
-75
- C3 -
2E5A
5
LIPT_BOVIN
A:
[12-256]
-------
S
N
D
V
Y
H
N
L
A
V
E
D
W
I
H
D
H
M
N
L-
E
G
K
P
V
L
F
L
W
R
N
S
P
T
V
V
I
G
R
H
Q
N
P
W
Q
-
E
C
N
L
N
L
M
R
E
E
G
V
K
L
A
R
R
R
S
G
G
G
T
V
Y
H
D
M
G
N
I
-
N
L
T
F
F
----
T
T
--
K
K
K
Y
D
R
M
E
N
L
K
L
V
V
R
A
L
K
A
V
H
P
H
L
D
V
Q
A
-
T
-
K
----------
R
F
D
L
L
L
----------
D
G
---
Q
F
K
I
S
G
T
A
S
K
I
G
R
N
A
A
Y
H
H
C
T
L
L
C
G
T
D
G
T
F
L
S
S
L
L
K
S
P
Y
Q
G
I
R
S
N
A
T
A
S
T
P
A
L
V
K
N
L
M
E
K
-
D
P
T
L
T
C
E
V
V
I
N
A
V
A
T
E
Y
A
T
S
-
H
-
Q
-
I
-
D
---
N
H
I
H
L
I
N
P
T
D
---
E
T
-
V
F
P
G
I
N
S
K
A
I
--
E
L
Q
T
W
E
W
I
Y
G
K
T
P
K
F
S
V
D
T
S
F
T
V
L
--
H
S
H
V
E
I
K
V
F
I
D
V
K
N
G
R
I
E
V
C
N
I
E
A
-
P
D
H
W
L
-
P
L
E
I
C
D
Q
L
N
S
S
L
I
G
S
K
F
S
P
I
E
T
T
V
D
E
L
H
S
K
W
N
I
L
C
E
K
I
K
G
I
M
---
8
PsiBlast_PDB
64.13
28%
-83
- C3 -
3A7U
-
LIPT_BOVIN
A:
[12-256]
-------
S
N
D
V
Y
H
N
L
A
V
E
D
W
I
H
D
H
M
N
L-
E
G
K
P
V
L
F
L
W
R
N
S
P
T
V
V
I
G
R
H
Q
N
P
W
Q
-
E
C
N
L
N
L
M
R
E
E
G
V
K
L
A
R
R
R
S
G
G
G
T
V
Y
H
D
M
G
N
I
-
N
L
T
F
F
----
T
T
--
K
K
K
Y
D
R
M
E
N
L
K
L
V
V
R
A
L
K
A
V
HP
H
L
D
V
Q
A
-
T
-
K
----------
R
F
D
L
L
L
----------
D
G
---
Q
F
K
I
S
G
T
A
S
K
I
G
R
N
A
A
Y
H
H
C
T
L
L
C
G
T
D
G
T
F
L
S
S
L
L
K
------------------
K
N
L
M
E
K
-
D
P
T
L
T
C
E
V
V
I
N
A
V
A
T
E
Y
A
T
S
-
H
-
Q
-
I
-
D
---
N
H
I
HLIN
P
T
D
---
E
T
-
V
F
P
G
I
N
S
K
A
I
--
E
L
Q
T
W
E
W
I
Y
G
K
T
P
K
F
S
V
D
T
S
F
T
V
L
--
H
E
Q
S
H
V
E
I
K
V
F
I
D
V
K
N
G
R
I
E
V
C
N
I
-
E
A
P
D
H
-
W
L
P
L
E
I
C
D
Q
L
N
S
S
L
I
G
S
K
F
S
P
I
E
T
T
V
L
T
S
I
L
H
R
T
Y
P
G
D
D
E
L
H
S
K
W
11
PsiBlast_PDB
64.02
29%
-93
- C3 -
2ARU
2
LPLAN_THEAC
A:
[35-255]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
PVNKKT
D
I
M
A
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
V
P
----------
S
T
R
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
L
------------------------------------------------------------------------------------------
10
PsiBlast_PDB
63.48
29%
-97
- C3 -
2ART
3
LPLAN_THEAC
A:
[35-255]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
PVNKKT
D
I
M
A
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
V
P
----------
S
T
R
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
L
------------------------------------------------------------------------------------------
12
PsiBlast_PDB
63.16
29%
-101
- C3 -
2C7I
-
LPLAN_THEAC
A:
[35-255]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
PVNKKTDIMA
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
--------------
R
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
L
R
-----------------------------------------------------------------------------------------
9
PsiBlast_PDB
62.22
29%
-90
- C3 -
3R07
3
LPLAN_THEAC
A:
[58-278]
--------------------------------
I
L
R
F
Y
R
H
D
R
S
V
I
I
G
Y
F
Q
V
A
E
E
-
E
V
D
L
D
Y
M
K
K
N
G
I
M
L
A
R
R
Y
T
G
G
G
A
V
Y
H
D
L
G
D
L
-
N
F
S
V
V
R
S
S
D
D
M
--
D
I
T
S
M
F
R
T
M
N
E
A
V
V
N
S
L
R
I
L
--
G
L
D
A
R
P
-
G
-
E
----------
L
N
D
V
S
I
P
V--------
G
E
---
K
-
K
I
M
G
A
A
G
A
M
R
K
G
A
K
L
W
H
A
A
M
L
V
H
T
D
L
D
M
L
S
A
V
L
K
V
P
D
E
K
F
R
D
K
I
A
K
S
T
R
E
R
V
A
N
V
T
D
F
V
D
--
V
S
I
D
E
V
R
N
A
L
I
R
G
F
S
E
T
L
H
I
D
-
F
-
R
---
E
D
T
----
I
T
E
---
K
E
-
E
S
L
A
R
E
L
F
D
K
--
K
Y
S
T
E
E
W
N
M
G
L
L
R
K
E
V
V
-------------------------------------------------------------------------------------
4
PsiBlast_PDB
57.46
30%
-10
- C3 -
1X2G
-
LPLA_ECOLI
A:
[3-302]
L
R
L
L
I
S
D
S
Y
D
P
W
F
N
L
A
V
E
E
C
I
F
R
Q
M
P
--
A
T
Q
R
V
L
F
L
W
R
N
A
D
T
V
V
I
G
R
A
Q
N
P
W
K
-
E
C
N
T
R
R
M
E
E
D
N
V
R
L
A
R
R
S
S
G
G
G
A
V
F
H
D
L
G
N
T
-
C
F
T
F
M
-
A
G
K
P
E
-----
Y
D
K
T
I
S
T
S
I
V
L
N
A
L
N
A
L
--
G
V
S
A
E
A
-
S
-
G
----------
R
N
D
L
V
V
K
T
VE------
G
D
---
R
-
K
V
S
G
S
A
Y
R
E
T
K
D
R
G
F
H
H
G
T
L
L
L
N
A
D
L
S
R
L
A
N
Y
L
N
P
D
K
K
K
L
A
A
K
G
------
R
V
T
N
L
T
E
L
L
P
G
-
I
T
H
E
Q
V
C
E
A
I
T
E
A
F
F
A
H
-
Y
G
E
R
V
-
E
---
A
E
I
----
I
S
P
---
N
K
-
T
P
D
L
P
N
F
A
E
T
F
A
R
Q
S
S
W
E
W
N
F
G
Q
A
P
A
F
S
H
L
L
D
E
R
F
T
--
W
G
G
V
E
L
H
F
D
V
E
K
G
H
I
T
R
A
Q
V
F
T
D
S
-
L
N
P
A
P
-
L
E
A
L
A
G
R
L
Q
G
C
L
Y
R
A
D
M
L
Q
Q
E
C
E
A
L
L
V
D
F
P
E
Q
E
K
E
L
R
E
L
S
A
W
M
A
G
48
HHSearch
57.41
19%
-68
- C3 -
1W66
1
LIPB_MYCTU
A:
[14-218]
I
D
V
R
Q
L
G
T
V
D
Y
R
T
A
W
Q
L
Q
R
E
L
A
D
A
R
V
A
-
G
G
A
D
T
L
L
L
L
E
H
P
A
V
Y
T
A
G
R
R
T
E
T
H
--
E
-----
R
P
I
D
G
T
P
V
V
D
T
D
R
G
G
K
I
T
W
H
G
P
G
Q
L
-
V
G
Y
P
I
-
I
G
L
A
E
PL
D
V
V
N
Y
V
R
R
L
E
E
S
L
I
Q
V
C
A
D
L
--
G
L
H
A
G
R
V
D
-
G
----------
R
S
G
V
W
L
----------
P
G
RP
A
R
-
K
V
A
A
I
G
V
R
V
S
R
A
T
T
L
H
G
F
A
L
N
C
D
C
D
L
A
A
F
T
A
I
V
-
P
C
G
--
I
S
-------
D
A
A
V
T
S
L
S
A
E
L
G
R
T
V
T
V
D
E
V
R
A
T
V
A
A
A
V
C
A
A
-
L
D
G
-
V
L
P
-------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
56.39
16%
-65
- C3 -
2QHS
1
LIPB_THET8
A:
[23-228]
F
L
V
E
D
L
G
L
V
P
Y
G
E
A
W
A
Y
Q
K
R
V
H
R
E
V
V
A
G
N
R
P
P
T
L
L
L
L
E
H
P
R
V
I
T
L
G
R
K
A
T
G
E
N
L
L
F
P
E
S
W
Y
R
E
N
G
F
E
L
Y
W
V
E
R
G
G
D
V
T
Y
H
G
P
G
Q
L
V
G
Y
P
I
F
-
P
V
G
R
---
E
V
R
R
F
L
R
Q
I
E
E
A
I
V
R
V
A
A
G
Y
--
G
I
S
A
Y
P
-
T
P
G
----------
Y
A
G
V
W
V
----------
G
E
---
D
-
K
L
C
A
I
G
V
A
V
K
E
G
V
S
F
H
G
F
A
L
N
V
N
T
D
L
N
D
F
T
V
I
V
-
P
C
--
G
L
K
-------
G
K
G
V
T
S
L
E
K
L
L
G
R
K
V
P
M
E
E
A
K
A
R
V
V
A
A
F
A
E
V
-
F
G
L
-
R
-
P
---
V
---------------------------------------------------------------------------------------------------------------------------------