@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0902: (2015-12-04 )
MDIFSAIDSKFWASIMENPWMILIHLMDIIIVAVLIYKFIKALAGTKIMSLIQGVILFIIIRFVSEWIGLTTITFLMNQIVTYGVIAGVVIFAPEIRTGLEKFGRTPQLFTQRSQLSSDEKLVDALVKAVAYMSPRKIGALISIERTQTLQEYIATGIPLDADISSELLINIFIPNTPLHDGAVIVKDKKIATACSYLPLSESSSISKEFGTRHRAAIGLSENSDALTVIVSEETGGISVALKGEFLHDLSKDSFEAILRTQLIQNQEENSKLAWYNQLLRRK
Atome Classification :
(20 SA)
------------------------------------------------------.........10........-20....--..-.-.30---------........40...---....-.50......--..60........70.------------------....--...80........90........100.---.------------.....110.......-----120.......130--------------..---.....140.-....---------.-.150.......-----160.......170.---------....-----..180......--.--190....-...200......-.210.......220.....-----..230.......240.....--------------..250--.....---..260.-......270..--.....280.-------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------M
D
I
F
S
A
I
D
S
K
F
W
A
S
I
MEN
P
-
W
M
I
L
I
H
--
L
M
-
D
-
I
I
I
---------
V
A
V
L
I
Y
K
F
I
K
A
LA---
G
T
K
I
-
M
S
L
I
Q
G
V
I
L
--
F
I
I
I
R
F
V
S
E
W
I
G
L
T
T
------------------
I
T
F
L
--
M
N
Q
I
V
T
Y
G
V
I
A
G
V
V
I
F
A
P
E
I
R
T
G
L
E
K
F---G------------RT
P
Q
L
F
T
Q
R
SQLS
S
D
-----
E
K
L
V
D
A
L
V
K
A
V
A
Y--------------MS---PR
K
I
G
A
L
I
S
-
I
E
R
T
---------
Q
-
T
L
Q
E
Y
I
ATGIP-----LDADISS
E
L
L
I
N
I
F
---------IPNT-----PLHD
G
A
V
I
V
KD--K--
K
I
A
T
A
C
S-YLPLSESS
S
I
S
K
-
E
FGTR
H
R
A
A
IGLSENS
D
A
L
-----
T
V
I
V
SEETG
G
I
S
V
A
L
K
G
E
F
L
--------------
H
D
L
S
K
--
D
S
F
E
A
---
I
L
R
T
Q
L
-IQNQEENS
K
L
A
--
W
Y
N
Q
L
LRRK-------------------------------------
10
PsiBlast_CBE
99.33
58%
-153
- C5 -
4RV7
2
DACA_LISMO
D:
[31-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
S
I
E
K
S
T
Q
Y
--------------
M
A
---
K
R
R
I
G
A
L
I
S
-
V
A
R
D
---------
T
-
G
M
D
D
Y
I
E
T
G
I
P
-----
L
N
A
K
I
S
S
Q
L
L
I
N
I
F
---------
I
P
N
T
-----
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
-
Y
L
P
L
S
D
S
P
F
L
S
K
-
E
L
G
T
R
H
R
A
A
L
G
I
S
E
V
T
D
S
I
-----
T
I
V
V
S
E
E
T
G
G
I
S
L
T
K
G
G
E
L
F
--------------
R
D
V
S
E
--
E
E
L
H
K
---
I
L
L
K
E
L
-
V
T
---------------------------------------------------------
1
PsiBlast_PDB
98.45
58%
-154
- C5 -
4RV7
4
DACA_LISMO
A:
[31-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
S
I
E
K
S
T
Q
Y
--------------
M
A
---
K
R
R
I
G
A
L
I
S
-
V
A
R
D
---------
T
-
G
M
D
D
Y
I
E
T
G
I
P
-----
L
N
A
K
I
S
S
Q
L
L
I
N
I
F
---------
I
P
N
T
-----
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
-
Y
L
P
L
S
D
S
P
F
L
S
K
-
E
L
G
T
R
H
R
A
A
L
G
I
S
E
V
T
D
S
I
-----
T
I
V
V
S
E
E
T
G
G
I
S
L
T
K
G
G
E
L
F
--------------
R
D
V
S
E
--
E
E
L
H
K
---
I
L
L
K
E
L
-
V
T
V
T
-------------------------------------------------------
12
PsiBlast_CBE
97.68
58%
-153
- C5 -
4RV7
3
DACA_LISMO
B:
[31-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
S
I
E
K
S
T
Q
Y
--------------
M
A
---
K
R
R
I
G
A
L
I
S
-
V
A
R
D
---------
T
-
G
M
D
D
Y
I
E
T
G
I
P
-----
L
N
A
K
I
S
S
Q
L
L
I
N
I
F
---------
I
P
N
T
-----
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
-
Y
L
P
L
S
D
S
P
F
L
S
K
-
E
L
G
T
R
H
R
A
A
L
G
I
S
E
V
T
D
S
I
-----
T
I
V
V
S
E
E
T
G
G
I
S
L
T
K
G
G
E
L
F
--------------
R
D
V
S
E
--
E
E
L
H
K
---
I
L
L
K
E
L
-
V
T
V
T
-------------------------------------------------------
11
PsiBlast_CBE
97.48
58%
-153
- C5 -
4RV7
3
DACA_LISMO
C:
[31-173]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
E
S
I
E
K
S
T
Q
Y
--------------
M
A
---
K
R
R
I
G
A
L
I
S
-
V
A
R
D
---------
T
-
G
M
D
D
Y
I
E
T
G
I
P
-----
L
N
A
K
I
S
S
Q
L
L
I
N
I
F
---------
I
P
N
T
-----
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
-
Y
L
P
L
S
D
S
P
F
L
S
K
-
E
L
G
T
R
H
R
A
A
L
G
I
S
E
V
T
D
S
I
-----
T
I
V
V
S
E
E
T
G
G
I
S
L
T
K
G
G
E
L
F
--------------
R
D
V
S
E
--
E
E
L
H
K
---
I
L
L
K
E
L
-
V
T
V
T
-------------------------------------------------------
13
HHSearch
83.27
49%
-128
- C5 -
2FB5
-
?
A:
[74-203]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
S
S
S
F
I
T
T
A
I
Q
H
--------------
L
S
---
A
R
K
H
G
A
L
I
V
-
V
E
R
N
---------
E
-
T
L
E
A
L
I
Q
T
G
T
T
-----
L
N
A
H
L
T
A
P
L
L
E
S
I
F
---------
Y
P
G
N
-----
P
L
H
D
G
A
V
L
V
K
N
--
N
--
H
I
V
S
A
A
N
-
I
L
P
L
T
K
S
T
E
V
D
P
-
E
L
G
T
R
H
R
A
A
I
G
L
S
E
K
S
D
A
L
-----
I
L
V
V
S
E
E
T
G
R
T
S
F
A
L
N
G
I
L
Y
--------------
T
I
S
L
-----------------------------------------------------------------------------
2
PsiBlast_PDB
78.70
53%
-133
- C5 -
2FB5
-
?
A:
[80-198]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
T
A
I
Q
H
--------------
L
S
---
A
R
K
H
G
A
L
I
V
-
V
E
R
N
---------
E
-
T
L
E
A
L
I
Q
T
G
T
T
-----
L
N
A
H
L
T
A
P
L
L
E
S
I
F
---------
Y
P
G
N
-----
P
L
H
D
G
A
V
L
V
K
N
--
N
--
H
I
V
S
A
A
N
-
I
L
P
L
T
K
S
T
E
V
D
P
-
E
L
G
T
R
H
R
A
A
I
G
L
S
E
K
S
D
A
L
-----
I
L
V
V
S
E
E
T
G
R
T
S
F
A
L
N
G
I
L
Y
--------------
T
I
S
L
-----------------------------------------------------------------------------
14
HHSearch
63.56
23%
-94
- C5 -
3C1Y
1
DISA_THEMA
A:
[27-181]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
Q
E
L
I
E
K
I
K
L
I
---
S
------------
P
G
----------------------
T
E
L
R
K
A
L
D
D
--------------
I
I
---
N
A
N
F
G
A
L
I
F
-
L
V
D
D
---------
P
K
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
DI
T
--
K
I
Y
Y
A
N
V
-
H
L
V
P
D
P
T
-
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
5
PsiBlast_PDB
56.68
29%
-91
- C5 -
3C21
1
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
4
PsiBlast_PDB
56.38
29%
-91
- C5 -
3C1Z
-
DISA_THEMA
A:
[37-139]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
8
PsiBlast_PDB
56.27
29%
-96
- C5 -
4YXJ
2
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
7
PsiBlast_PDB
56.11
29%
-87
- C5 -
4YVZ
3
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
3
PsiBlast_PDB
55.26
29%
-90
- C5 -
3C1Y
1
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
6
PsiBlast_PDB
54.37
29%
-88
- C5 -
3C23
2
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
-------------------
S
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
9
PsiBlast_PDB
53.85
29%
-90
- C5 -
4YXM
2
DISA_THEMA
A:
[57-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
I
F
L
V
D
D
P
---------
K
-
K
Y
E
D
V
I
Q
G
G
F
W
-----
L
D
T
D
F
S
A
E
K
L
Y
E
L
S
---------
K
M
N
----------
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
-
H
L
-
V
P
D
P
T
I
P
T
G
-
E
T
G
T
R
H
R
T
A
E
R
L
A
K
Q
T
G
K
V
-----
V
I
A
V
S
R
R
R
N
I
I
S
L
Y
Y
K
N
Y
K
Y
--------------
V
V
N
Q
V
--
D
F
L
I
S
---
K
V
T
Q
A
I
-
S
T
L
E
K
Y
K
D
N
F
N
--
K
L
L
S
E
L
E
V
L
-------------------------------------
32
Fugue
47.28
13%
-79
- C1 -
4CI2
2
CRBN_CHICK
B:
[71-451]
---------------------------------------------------MIN
F
D
T
S
L
P
T
S
H
M
Y
L
G
S
D
M
E
E
F
-
H
G
R
T
L
H
--
D
D
-
D
S
C
Q
V
---------
I
P
V
L
P
H
V
M
V
M
L
I
P
---
G
Q
T
L
P
L
Q
L
F
H
P
Q
E
V
--
S
M
V
R
N
L
I
Q
K
D
R
T
F
A
V
------------------
L
A
Y
S
NV
R
E
R
E
A
H
F
G
T
T
A
E
I
Y
A
Y
R
E
E
Q
E
Y
G
I
E
T
V
K
V
K
A
------------
I
G
R
Q
R
F
K
V
L
E
I
R
T
Q
S
-----
D
G
I
Q
Q
A
K
V
Q
I
L
P
E
R
V
L
P
S
TMSAVQLQS
L
S
---
R
R
H
I
R
A
F
R
Q
-
W
W
Q
K
---------
Y
-
Q
K
R
K
F
H
C
A
S
L
T
SWP
P
W
L
Y
S
L
Y
D
A
E
T
L
M
E
R
V
---------
K
R
Q
L
H
E
W
D
E
N
L
K
D
E
S
L
P
T
N
P
--
I
--
D
F
S
Y
R
V
A
A
C
L
P
I
D
D
A
L
R
I
Q
L
L
K
I
G
S
A
I
Q
R
L
R
C
E
L
D
I
M
N
K
C
-----
T
S
L
C
C
K
Q
C
Q
D
T
E
I
T
T
K
N
E
I
F
SLSLCGP
M
A
A
Y
V
N
P
H
G
Y
I
H
--
E
T
L
T
V
---
Y
K
A
C
N
L
-
N
L
S
G
R
P
S
T
E
H
S
--
W
F
P
G
Y
A
W
T
I
A
Q
CRICGNHM
G
W
K
F
T
A
TKKDMSPQKFWGLTRSALLPR
24
Fugue
45.92
10%
-66
- C4 -
3SK9
-
CAS3_THET8
A:
[4-260]
----------------------------------------------------------
S
M
A
A
L
A
L
W
A
K
S
G
N
P
F
-
H
P
L
L
A
H
--
M
L
-
D
-
T
A
A
---------
V
A
L
A
V
L
R
M
E
P
P
R
T
---
R
A
L
Y
-
A
E
D
W
G
-------------------
L
P
------------------
E
E
G
A
--
L
A
W
A
A
A
L
V
G
L
H
D
L
G
K
A
S
P
V
F
Q
A
W
V
A
H
G
---
V
------------
F
T
E
L
F
L
R
R
L
L
K
E
K
G
L
-----
P
---
E
R
A
A
N
D
L
A
A
--------------
A
L
---
G
A
H
H
G
F
P
A
N
-
A
E
E
K
---------
S
-
R
A
R
R
H
L
R
T
E
D
P
-----
L
W
K
E
A
R
R
W
L
L
E
E
V
F
---------
R
R
L
----------------------------
G
-
A
P
L
P
P
A
R
P
E
A
V
L
-
R
V
M
A
L
A
S
F
A
D
W
V
A
S
D
P
S
L
F
-----
P
Y
G
R
D
P
R
R
G
D
Y
L
K
E
A
L
R
L
A
Q
--------------
E
A
L
N
R
--
L
G
W
P
A
---
F
A
K
A
Q
R
-
R
E
F
G
E
L
F
P
Y
I
-------------------------------------------------
29
Fugue
41.25
13%
-101
- C4 -
1YT3
11
RND_ECOLI
A:
[1-375]
M
N
Y
Q
M
I
TT
D
D
A
L
A
S
L
C
E
A
V
RAFP
A
I
A
L
D
T
E
F
V
R
T
RTYYPQLG
L
I
Q
L
F
DGE
H
L
A
L
I
D
P
L
G
I
T
D
W
S
P
L
K
A
I
L
R
D
P
S
I
T
K
F
L
H
AG
S
E
-
D
-
L
E
V
---------
F
L
N
V
F
G
E
L
P
Q
P
L
I
---
D
T
Q
I
-
L
A
A
F
C
G
R
P
M
S-
W
G
F
A
S
M
V
E
E
Y
S
G
V
T
L
D
KSESRTDWLARPLT
E
R
Q
C
E
Y
A
--
A
A
D
V
W
Y
L
L
P
I
T
A
K
L
M
V
E
T
E
A
S
G
W
L
P
A
A
---
L
------------
D
E
C
R
L
M
Q
M
R
R
Q
E
V
V
A
-----
P
E
D
A
W
R
D
I
T
N
A
W
Q
--------------
L
R
---
T
R
Q
L
A
C
L
Q
L
-
L
-
A
D
---------
W
-
R
L
R
K
A
R
E
R
D
L
A
-----
V
N
F
V
V
R
E
E
H
L
W
S
V
A
R
Y
MPGS
L
G
E
L
D
S
L
-----
G
L
S
G
S
E
I
R
F
H
G
--
K
--
T
L
L
A
L
V
E
-
K
A
Q
T
L
P
E
D
A
L
P
Q
-
P
M
-
L
N
L
M
D
M
P
G
Y
R
K
A
F
K
A
I
-----
K
S
L
I
T
D
V
S
E
T
H
K
I
--
S
A
E
L
L
--------------
A
--
S
R
--
R
Q
I
N
Q
---
L
L
N
W
H
W
K
L
K
P
Q
N
N
L
P
E
L
I
SG
W
R
G
E
L
M
A
E
A
L
H
N
L
L
Q
EYPQ---------------------------
31
Fugue
38.44
12%
-75
- C2 -
1XSZ
-
?
A:
[-1-354]
-------ASH
P
E
I
E
K
A
Q
R
E
I
I
E
A
F
N
A
K
P
K
N
G
I
N
K
I
K
E
I
C
E
Q
Y
KIS
P
N
E
E
I
A
E
F
F
H
Q
Q
R
K
N
L
D
L
E
A
V
G
D
Y
L
S
S
P
-
E
A
E
N
Q
Q
--
V
L
-
K
-
A
F
T
S
Q
MNFNGQS
F
V
E
G
L
R
T
F
L
K
T
F
K
---
L
P
G
E
-
A
Q
K
I
D
R
L
V
Q
--
S
F
S
G
A
Y
F
Q
Q
N
P
D
V
V
S
------------------
N
A
D
A
--
A
Y
L
L
A
F
Q
T
I
M
L
N
T
D
L
H
N
P
S
I
P
---
E
K
N
---
K
------------
M
T
V
D
G
L
K
R
N
L
R
G
G
N
N
GGDFD
A
K
F
L
E
E
L
Y
S
E
I
K
A
--------------
K
P
F
E
L
N
F
V
K
T
S
P
G
Y
-
E
L
T
S
---------
T
-
T
L
N
K
D
S
T
F
K
K
L
-----
D
S
F
L
H
S
T
D
V
N
I
N
T
V
---------
F
P
G
I
-----
G
D
N
V
K
T
T
V
D
Q
P
--
K
--
S
W
L
S
F
F
T
-
G
Y
K
G
T
I
T
L
T
D
N
K
-
T
S
A
Q
A
T
I
Q
V
Y
T
P
N
I
F
S
K
W
L
FGE
Q
P
R
V
I
I
Q
P
G
Q
T
K
E
S
I
D
L
A
A
K
A
A
--------------
A
D
F
S
S
PV
K
N
F
K
A
T
YD
Y
E
V
G
D
L
-
I
K
A
Y
D
N
Q
K
K
L
I
--
T
I
E
R
N
L
A
L
K
A------------------------------------
26
Fugue
37.20
15%
-63
- C4 -
4D10
1
CSN5_HUMAN
E:
[24-333]
----------------------------------------------------SI
D
E
I
Y
K
Y
D
K
K
Q
Q
Q
E
I
L
A
A
K
P
-
W
T
K
D
H
H
--
Y
F
K
Y
-
C
K
I
---------
S
A
L
A
L
L
K
M
V
M
H
A
R
S
G
G
N
L
E
V
-
M
G
L
M
L
G
K
V
D
GE
T
M
I
I
M
D
S
F
A
L
P
V
E
G
T
------------------
E
T
R
V
--
N
A
Q
A
A
A
Y
E
Y
M
A
A
Y
I
E
N
A
K
Q
V
G
R
L
E
N
A
I
---
G
W
Y
H
S
HPGY
G
C
W
L
S
G
I
D
V
S
T
Q
M
L
N
Q
Q
F
Q
-----
E
P
F
V
A
V
V
I
D
P
T
R
T
--------------
I
S
---
A
G
K
V
N
--
L
G
-
A
F
R
T
Y
P
KG
Y
K
P
P
D
E
-
G
P
S
E
Y
--
Q
T
I
P
-----
L
N
K
I
E
D
F
G
V
H
C
K
Q
Y
---------
Y
A
L
E
-----
V
S
Y
F
K
S
S
L
D
R
K
--
L
--
L
E
L
L
W
N
K
-
Y
W
V
N
T
L
S
S
S
--
S
-
L
L
T
N
A
D
Y
T
T
G
Q
V
F
D
L
S
E
K
L
-----
E
Q
S
E
A
Q
L
G
R
G
-----
S
E
D
K
L
--------------
A
K
A
T
R
--
D
S
C
K
T
---
T
I
E
A
I
H
-
G
L
M
S
Q
V
I
K
D
K
L
--
F
N
Q
I
N
I
----------------------------------------
25
Fugue
37.10
24%
-56
- C5 -
2JX5
-
?
A:
[1-69]
-----------------------------------------------------------------------------------------------------------------------------------------------
M
L
V
------------------
I
V
R
L
--
Q
D
Q
T
L
P
F
E
L
P
A
G
A
R
--
A
S
Q
L
S
N
L
L
S
S
S
---
G
------------
M
A
F
S
L
H
T
Q
G
R
V
L
S
E
A
-----
A
E
L
N
D
-
K
M
V
I
D
A
F
--------------
V
P
---
A
D
G
A
G
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------