@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1017: (2015-12-04 )
MAFESLTERLQGVFKNIRGKKKLSEKDVQEVTKEIRLALLEADVALPVVKTFIKHVRERAVGHEIIDTLDPTQQIVKIVNEELTDLLGAETSEIEKSPKIPTIIMMVGLQGAGKTTFAGKLANKLIKEDNARPMMIAADIYRPAAIDQLKTLGSQINVPVFDMGTNHSAVEIVTKGLEQARENRNDYVLIDTAGRLQIDATLMQELHDVKAIAQPNEILLVVDSMIGQEAANVAEEFNRQLSISGVVLTKIDGDTRGGAALSVREITGKPIKFTGTGEKITDIETFHPDRMASRILGMGDLLTLIERASQEYDEKRSMELAEKMRENTFDFNDFIDQLDQVQNMGPMEDLLKMLPGMANNPAMKNFKVDENEIARKRAIVSSMTPEERENPDLLNPSRRRRIAAGSGNTFVDVNKFIKDFNQAKQMMQGVMSGDMNKMMKKMGIDPNNLPKDMPGMDGMDMSNLEGMMGQNGMPDLSSLGGDMDFSQMFGGGLKGKVGAFAAKQSMKRMANKMKKAKKKRK
Atome Classification :
(46 SA)
.........10........20----------.........30........40........50........60....-....70........80........90.-------.-..--....100.-----......110.......120.......130......-.140.......150.......160........170.......180.......190.......200.....---------..210.------.-----.------.....220.......230.......240........250.......260.......270.......280.......290.......300.......310.....-...320..-..-...330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
F
E
S
L
T
E
R
L
Q
G
V
F
K
N
IRGK-----------KKL
S
E
K
D
V
Q
E
V
T
K
E
I
R
L
A
L
L
EADV
A
L
P
V
V
K
T
F
I
K
H
V
R
E
RAV
G
H
E
I
-
I
DTLD
P
T
Q
Q
I
V
K
I
V
N
E
E
L
T
D
L
LGA
E
T
S
-------
E
-IE--KSPKI
P
T
I
-----
I
M
M
V
GLQGAGKT
T
F
A
G
K
L
A
N
K
L
I
KEDNAR
P
M
M
I
A
A-DIYRP
A
A
I
D
Q
L
K
T
LGSQIN
V
P
V
F
-DMGTN
H
S
A
V
E
I
V
T
K
G
L
E
Q
A
R
ENRN
D
Y
V
L
I
DTAG
R
L
Q
I
D
A
T
L
M
Q
E
L
H
---------
D
V
K
-
A
I------A-----Q------P
N
E
I
L
L
V
V
D
S
M
I
G
Q
E
A
A
N
V
A
E
E
F
N
R
QL-SIS
G
V
V
L
T
K
IDGDTRG
G
A
A
L
S
V
REITGK
P
I
K
F
TGTGE
K
I
T
DIETF
H
P
D
R
M
A
S
R
I
LG
M
G
D
L
L
T
L
I
E
R
A
S
Q
-
E
Y
D
E
K
R
-
S
M
E
L
A
E
K
M
-
R
E-NTF
D
F
N
D
F
I
D
Q
L
D
Q
VQNMG
P
M
E
D
L
L
K
MLPGMANNPAMKNFKV
D
E
N
E
I
A
R
K
R
A
I
V
SSMTPEERENPDLL
N
P
S
R
R
R
R
IAAGSGN
T
F
V
D
V
N
K
F
I
K
D
F
N
Q
A
K
Q
M
M
Q
G
V
MSG
D
M
N
K
M
M
K
KMGIDPNNLPKDMPGMDGM
D
M
S
N
L
E
G
M
MGQNGMP
D
L
S
S
LGGDM
D
F
S
Q
M
FGGGLKG
K
V
G
A
F
A
A
K
Q
S
M
K
R
M
A
N
K
M
K
K
A
K
KKRK
21
PsiBlast_CBE
93.33
48%
-87
- C9 -
2XXA
3
SRP54_ECOLI
C:
[7-421]
-------
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------
T
-
L
N
--
L
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
-
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
---------
Q
V
H
-
A
S
------
I
-----
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
-
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
-
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
----------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
M
M
K
K
M
K
K
-----------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.32
48%
-85
- C9 -
2XXA
3
SRP54_ECOLI
A:
[4-421]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------
T
-
L
N
--
L
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
-
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
---------
Q
V
H
-
A
S
------
I
-----
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
-
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
-
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
---------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
M
M
K
K
M
K
K
-----------------------------------------------------------------------------------------
102
HHSearch
87.99
47%
-58
- C- -
2XXA
3
SRP54_ECOLI
A:
[4-432]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
-
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------
T
-
L
N
--
L
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
-
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
---------
Q
V
H
-
A
S
------
I
-----
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
-
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
K
K
G
-
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
---------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
M
M
K
K
M
K
K
-----------------------------------------------------------------------------------------
23
PsiBlast_CBE
87.42
42%
-79
- C8 -
2FFH
7
SRP54_THEAQ
B:
[2-416]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
-
A
------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
-----
Q
G
L
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
-----------------------------------------------------------------------------------------
7
PsiBlast_PDB
87.22
33%
-80
- C9 -
3DM5
10
SRP54_PYRFU
A:
[1-435]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
-
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
-------
P
-
I
E
--
I
K
E
K
-
P
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
-
R
Y
F
Q
K
R
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
-
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
---------
Q
I
S
-
N
V
------
I
-----
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
-
K
E
E
D
I
E
R
F
-
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
S
-------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.21
42%
-78
- C8 -
2FFH
7
SRP54_THEAQ
A:
[2-416]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
-
A
------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
-----
Q
G
L
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
-----------------------------------------------------------------------------------------
101
HHSearch
86.69
34%
-79
- C9 -
3DM5
10
SRP54_PYRFU
A:
[1-435]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
-
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
-------
P
-
I
E
---
I
K
E
K
P
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
-
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
---------
Q
I
S
-
N
V
------
I
-----
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
-
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
-
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
S
-------------------------------------------------------------------------------------
103
HHSearch
86.53
43%
-74
- C8 -
2FFH
7
SRP54_THEAQ
A:
[1-418]
-
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
-
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
---------
L
---
P
V
L
K
D
R
N
L
-----
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
-
A
-------------------
E
L
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
Q
G
-----
L
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
-----------------------------------------------------------------------------------------
24
PsiBlast_CBE
86.28
51%
-94
- C9 -
4C7O
5
SRP54_ECOLI
C:
[2-298]
--
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------
T
-
L
N
--
L
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
-
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
---------
Q
V
H
-
A
S
------
I
-----
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.23
42%
-77
- C8 -
2FFH
9
SRP54_THEAQ
C:
[2-416]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
-
A
------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
-----
Q
G
L
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
-----------------------------------------------------------------------------------------
25
PsiBlast_CBE
85.86
33%
-80
- C9 -
3DM5
9
SRP54_PYRFU
B:
[1-434]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
-
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
-------
P
-
I
E
--
I
K
E
K
-
P
T
I
-----
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
-
R
Y
F
Q
K
R
G
Y
K
V
G
V
V
C
S
-
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
-
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
---------
Q
I
S
-
N
V
------
I
-----
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
-
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
-
K
E
E
D
I
E
R
F
-
L
R
-
G
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
--------------------
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
--------------------------------------------------------------------------------------
4
PsiBlast_PDB
84.72
51%
-98
- C9 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------
T
-
L
N
--
L
A
A
Q
P
P
A
V
-----
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
-
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
-
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
---------
Q
V
H
-
A
S
------
I
-----
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
-
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
84.24
40%
-82
- C9 -
3NDB
1
SRP54_METJA
B:
[1-420]
--
M
D
K
L
G
E
N
L
N
K
A
L
N
K
L
K
A
A
-----------
A
F
V
D
K
K
L
I
K
E
V
I
K
D
I
Q
R
A
L
I
Q
A
D
V
N
V
K
L
V
L
K
M
S
K
E
I
E
R
R
A
L
E
E
K
T
-
P
K
G
L
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
V
K
L
L
G
E
E
A
K
-------
K
-
L
E
--
L
N
P
K
K
Q
N
V
-----
I
L
L
V
G
I
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
R
Y
I
Q
K
R
G
L
K
P
A
L
I
A
A
-
D
T
Y
R
P
A
A
Y
E
Q
L
K
Q
L
A
E
K
I
H
V
P
I
Y
G
D
E
T
R
T
K
S
P
V
D
I
V
K
E
G
M
E
K
F
K
--
K
A
D
V
L
I
I
D
T
A
G
R
H
K
E
E
K
G
L
L
E
E
M
K
---------
Q
I
K
-
E
I
------
T
-----
N
------
P
D
E
I
I
L
V
I
D
G
T
I
G
Q
Q
A
G
I
Q
A
K
A
F
K
E
A
V
G
E
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
E
T
K
A
P
I
K
F
I
G
I
G
E
G
I
D
D
L
E
P
F
D
P
K
K
F
I
S
R
L
L
G
M
G
D
L
E
S
L
L
E
K
A
E
D
-
M
V
D
E
K
T
-
E
E
S
I
D
A
I
M
-
R
--
G
K
F
T
L
N
E
L
M
T
Q
L
E
A
I
E
N
M
-----------------------
L
T
E
A
K
I
K
K
Y
K
V
I
I
S
S
M
T
K
E
E
R
E
N
P
K
I
I
K
A
S
R
I
R
R
I
A
R
G
S
G
T
T
E
N
D
V
R
E
V
L
R
Y
Y
E
T
T
K
N
A
I
D
K
L
R
K
G
L
A
L
A
L
L
L
L
L
L
A
L
A
L
--------------------------------------------------------------------------
30
PsiBlast_CBE
83.42
45%
-102
- C9 -
2C03
10
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
83.39
45%
-96
- C9 -
1O87
7
SRP54_THEAQ
A:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
83.35
45%
-100
- C9 -
1FFH
1
SRP54_THEAQ
A:
[1-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
-------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
83.33
45%
-100
- C9 -
2J45
4
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
82.79
45%
-101
- C9 -
2J46
5
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
82.67
45%
-94
- C9 -
1RY1
-
SRP54_THEAQ
U:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
82.57
45%
-93
- C9 -
1O87
7
SRP54_THEAQ
B:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
82.51
45%
-94
- C9 -
1JPJ
1
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
82.22
45%
-100
- C9 -
1JPN
4
SRP54_THEAQ
B:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
82.13
44%
-94
- C9 -
1NG1
13
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
81.90
44%
-95
- C9 -
2J7P
11
SRP54_THEAQ
A:
[3-294]
---
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
81.78
44%
-99
- C9 -
2J7P
8
SRP54_THEAQ
B:
[4-294]
----
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
81.72
44%
-98
- C9 -
3NG1
6
SRP54_THEAQ
A:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
81.48
44%
-98
- C9 -
3NG1
7
SRP54_THEAQ
B:
[2-294]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KDRNL
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
81.45
45%
-96
- C9 -
1JPN
4
SRP54_THEAQ
A:
[2-296]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
80.94
44%
-98
- C9 -
1OKK
17
SRP54_THEAQ
A:
[4-293]
----
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
79.86
44%
-92
- C9 -
2NG1
4
SRP54_THEAQ
A:
[1-293]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
KD
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.48
44%
-87
- C9 -
1RJ9
3
SRP54_THEAQ
B:
[14-295]
--------------
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-----------------
R
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
-
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
-
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
-
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
---------
R
L
K
-
E
V
------
L
-----
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
-
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
75.16
33%
-93
- C9 -
3E70
3
?
C:
[7-324]
-
M
F
G
K
L
R
E
K
L
K
S
F
V
K
R
V
E
E
E
VEKEEEEVILT
V
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
-
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I------
D
L
I
E
EI
R
K
A
E
K
P
Y
V
-----
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
V
V
I
A
A
S
-
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
-
K
H
S
Y
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
---------
K
I
A
-
R
V
------
T
-----
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
-
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
72.71
35%
-89
- C9 -
3DMD
4
?
B:
[46-324]
--------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
-
R
I
G
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
--
E
T
S
RRID
L
I
E
E
-
I
R
--
K
A
E
K
-
P
Y
V
-----
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
-
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
-
K
H
S
Y
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
---------
K
I
A
-
R
V
------
T
-----
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
-
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
71.67
35%
-88
- C9 -
3E70
3
?
C:
[46-324]
--------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
-
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
--
E
T
S
RRIDLIE
E
-
I
R
--
K
A
E
K
-
P
Y
V
-----
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
-
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
-
K
H
S
Y
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
---------
K
I
A
-
R
V
------
T
-----
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
-
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115
HHSearch
71.18
31%
-82
- C9 -
2YHS
5
FTSY_ECOLI
A:
[225-495]
---------------------------------------
D
D
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
-
R
K
----
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
-------
P
-
L
N
--
V
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
V
M
L
A
A
G
-
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
-
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
---------
K
I
V
-
R
V
M
K
K
L
DV
E
-----
A
------
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
66.23
32%
-76
- C9 -
4C7O
5
FTSY_ECOLI
D:
[19-267]
----------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
Q
L
-
R
D
A
----
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
-------
P
-
L
N
--
V
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
--
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
-
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
---------
K
I
V
-
R
V
------
M
-----
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
65.23
31%
-73
- C9 -
2YHS
5
FTSY_ECOLI
A:
[238-495]
----------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
Q
L
-
R
D
A
----
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
-------
P
-
L
N
--
V
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
--
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
-
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
-
A
--------------------
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
64.97
32%
-72
- C9 -
4C7O
4
FTSY_ECOLI
B:
[19-267]
----------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
Q
L
-
R
D
A
----
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
-------
P
-
L
N
--
V
E
G
K
A
P
F
V
-----
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
--
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
-
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
---------
K
I
V
-
R
V
------
M
-----
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
-
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
63.99
36%
-94
- C9 -
1VMA
1
?
B:
[101-304]
-----------------------------------------------------------------------------------------------------------------------
P
E
P
P
F
V
-----
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
E
G
K
S
-
V
V
L
A
A
A
-
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
-
S
H
S
E
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
---------
K
V
H
-
R
V
------
V
-----
K
KKIPDA
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
-
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
60.60
31%
-77
- C9 -
1OKK
8
FTSY_THEAQ
D:
[114-301]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
KADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
60.12
31%
-71
- C9 -
2J7P
9
FTSY_THEAQ
E:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
KADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
59.62
31%
-77
- C9 -
2J7P
5
FTSY_THEAQ
D:
[94-281]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
59.09
31%
-72
- C9 -
1RJ9
3
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
58.95
31%
-80
- C9 -
2IYL
3
FTSY_THEAQ
D:
[95-282]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
KADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
57.52
31%
-76
- C9 -
2Q9B
11
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
55.85
31%
-74
- C9 -
2Q9C
7
FTSY_THEAQ
A:
[115-302]
--------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
-
G
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
-
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
-
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
---------
K
V
K
R
A
I
------
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
-
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------