@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1038: (2015-12-05 )
MGKTFWKDIYRSITTSKGRFSSILLLMMLGSFAFIGLKVSAPNMQRTAQNYLAHHHVMDITVFNSWGLDKHDQTVLESLKGSQVEFSYFVDTTPQQNSKSYRLYSNTKTISTFDLVKGRLPLNKSEIALSFQERKKYAIGDKINFKQDKNKLFSNTGPLTIVGFVNSTEIWSKTNLGSSQTGDGDLDSYGVLDKTAFHSPVYTMARVTFKDLRLINPFSISYKEKVAKYQEKVSRKLNIHNKIRYTKTKKESLRKIDEEEKSLLKAQKQINRLDNDSLAMPLSQRQAIQMKIKQDRLSLLKRTKELLKLRHNTQIMESPQIIVYNRTTFPGGQGYNTFDSSTNSTSKISNLFPIILYLVAALVTLTTMTRFVEEERTNAGILKALGYSDRQVIFKFIIYGFIAGTLGTTLGIIGGHYLLPRIISDIISKDLTIPNTQYHLFLNYSLLAFVFSLLSIVLPVFVITRRELKEKAAFLLLPKPPAKGSKIALEYINWIWKKLSFTQKVTARNIFRYKQRMIMTIFGVAGSVALLFSGLGIQSSLKQTVNEHFGRIMPYDILLTYNTNASPPKILELLSKDSKIDKYQPIHLENLDESIPGQINKQSISLFITDKKQLLPFIYLQEATTNKSLHLNNKGIIISKKLAQFYHVNTGDFIHLSHSQTLPSRKLKITGVVNANVGHYIFMTKQYYRTIFKKETKDNAFLVKLTKHKIANNLAEKLLEINGVESLTQNALQLASVEAVVRSLDGSMTILVVVSLLLAIVILYNLTNINLAERKRELSTIKVLGFYNEEVTLYIYRETIILSTIGVILGTISGTYLHRQMMLLIGSDQILFGEKVSPTTFIIPISVVVIILISLCFIVNHQLKKLNMLDALKSVD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........-80...-.....90...--....-.100.--....---..110.....---..120------.......130..---..---...140.......150.......160.......170.......180....---...190.....-..200.......210.......220.......230.......240.---......--250........260.......270.......280.......290.......--300.......--310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570..-.....580.......590........600.......610.......620.......630----........640.....-.---.650.......660.......670.....-----..680.......690...---....700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MG
K
T
F
W
K
D
I
Y
R
S
ITTSK
G
R
F
S
S
I
L
L
L
M
M
L
G
S
F
A
F
I
G
L
K
VSAP
N
M
Q
R
T
A
Q
N
Y
L
A
HH
H
V
M
D
I
T
V
FNSWGLDK
H
D
Q
T
V
L
E
SL-KGS
Q
V
-
E
F
S
Y
F
VDTTP--QQNS-K
S
Y
R
L
--
Y
SN
T
---
K
T
I
S
T
F
D
LVK---GRLPL------
N
K
S
E
I
A
L
S
F
Q
ER---KK---YAIGDKINF
K
Q
D
K
N
K
LFSNTG
P
L
T
I
V
G
F
VNS
T
E
I
W
SKTNLGSSQTGDGDL---DSYGVLDKTAF-HSP
V
Y
T
M
A
R
V
T
F
K
D
L
R
L
INPFS
I
S
Y
K
E
K
V
A
K
Y
Q
E
K
V
S
R
K
LNIHN
K
I
---
R
Y
TK
T
K
--
K
-
E
S
L
R
K
I
D
E
E
E
K
S
L
L
K
A
Q
K
Q
I
N
RLDNDSLAMP
L
S
Q
R
Q
A
I
Q
M
K
I
K
Q
D
R
L
S
L
--
L
K
R
T
K
E
L
L
K
L
--RHNTQIMES
P
Q
I
I
V
Y
NRTTFPGGQGYNTFDSSTNST
S
K
I
S
N
L
F
P
I
I
L
Y
L
V
A
A
L
V
T
L
T
T
M
T
R
F
V
E
E
ERTNA
G
I
L
K
ALGYS
D
R
Q
V
I
F
K
F
I
I
Y
G
F
I
A
G
T
L
G
T
T
L
G
IIG
G
H
Y
L
L
P
R
I
I
S
D
I
I
SKDLTIPNT
Q
Y
H
L
F
L
N
Y
S
L
L
A
F
V
F
S
L
L
S
I
V
L
P
V
F
V
I
T
R
R
E
L
K
EKA
A
F
L
L
LPKPPAKG
S
K
I
A
L
E
Y
I
N
W
I
W
K
KL
S
F
T
Q
K
V
T
A
R
N
I
F
R
Y
K
Q
R
M
I
M
T
I
FGV
A
G
S
V
A
L
L
F
SGLG
I
Q
S
S
L
K
Q
T
V
N
E
H
FGRIM
P
Y
D
I
L
L
T
YNTNAS
P
P
K
I
L
E
L
L
-SKDSKIDKYQP
I
H
L
E
N-L
D
E
SIPGQINK
Q
S
I
S
L
F
I
TDKKQL
L
P
F
I
Y
L
QEATTN
K
S
L
H
L-----NNK
G
I
I
I
S
K
K
L
A
Q
F
Y
H-V---NTG
D
F
I
H
LSHSQTLPSR
K
L
K
I
T
G
V
V
NANV-----
G
H
Y
I
F
M
T
K
Q
Y
Y
R
T
I
F
KKE---TKD
N
A
F
L
V
K
L
T
K
H
K
I
A
N
N
L
A
E
K
L
L
EIN
G
V
E
S
L
T
Q
N
A
L
Q
L
A
S
V
E
A
V
V
R
SLDGS
M
T
I
L
V
V
V
S
L
L
L
A
I
V
I
L
Y
NLTNI
N
L
A
E
R
K
REL
S
T
I
K
V
L
G
F
YNE
E
V
T
L
Y
I
Y
R
E
T
I
I
L
S
T
I
G
V
I
L
G
TI
S
G
T
Y
L
H
R
Q
M
M
L
L
IGSD
Q
I
L
FGEKVSP
T
T
F
I
I
P
I
S
V
V
V
I
I
L
I
S
L
C
F
I
V
N
H
Q
L
K
K
L
N
M
L
D
A
L
KSVD
12
HHSearch
76.97
15%
-35
- C1 -
3FTJ
-
MACB_AGGAC
A:
[344-488]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
N
T
L
-
S
K
Q
S
Y
I
Q
S
V
T
P
N
T
S
S
S
-
G
I
L
V
V
G
N
-
K
S
F
T
S
A
N
L
Y
G
I
G
-
E
Q
Y
F
D
V
E
G
L
K
L
K
Q
-
G
R
L
L
T
E
D
D
V
D
Q
S
N
Q
V
V
V
L
D
E
S
A
K
K
A
I
F
-
A
NEN
P
L
G
K
T
V
I
F
N
K
------
R
P
F
R
V
I
G
V
V
S
D
Q
------
S
L
N
L
Y
S
P
Y
S
T
V
L
N
K
I
T
G
G
---
S
R
I
G
S
I
T
V
K
I
S
D
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
75.03
28%
132
- C3 -
5BN4
1
?
A:
[487-567]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
L
Q
Q
D
A
F
D
E
N
D
S
Y
S
P
L
E
K
T
I
E
L
M
R
I
I
H
K
Y
Y
V
T
V
K
Q
L
L
G
K
I
P
L
E
E
I
E
Q
K
G
I
H
E
K
I
I
K
L
R
Y
K
S
L
K
E
F
R
-
E
E
I
K
A
I
E
Q
E
I
L
S
L
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
73.59
28%
146
- C3 -
5BN3
1
?
A:
[487-566]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
L
Q
Q
D
A
F
D
E
N
D
S
Y
S
P
L
E
K
T
I
E
L
M
R
I
I
H
K
Y
Y
V
T
V
K
Q
L
L
G
-
I
P
L
E
E
I
E
Q
K
G
I
H
E
K
I
I
K
L
R
Y
K
S
L
K
E
F
R
-
E
E
I
K
A
I
E
Q
E
I
L
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
73.02
28%
142
- C3 -
5BN5
-
?
A:
[487-566]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
L
Q
Q
D
A
F
D
E
N
D
S
Y
S
P
L
E
K
T
I
E
L
M
R
I
I
H
K
Y
Y
V
T
V
K
Q
L
L
G
-
I
P
L
E
E
I
E
Q
K
G
I
H
E
K
I
I
K
L
R
Y
K
S
L
K
E
F
R
-
E
E
I
K
A
I
E
Q
E
I
L
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
62.61
19%
89
* C1 *
3FTJ
-
MACB_AGGAC
A:
[338-449]
-----------------------------------------------------------------
Q
N
L
K
I
S
D
A
N
T
L
S
K
Q
-
S
Y
I
Q
S
V
T
P
N
T
S
S
S
G
I
L
V
V
G
N
K
S
F
T
S
A
N
L
--
Y
G
I
G
EQ
Y
F
D
V
E
G
L
K
L
K
Q
---
G
R
L
L
T
E
D
D
V
D
Q
S
N
Q
V
V
V
L
D
E
S
A
K
K
A
-
I
F
ANE
N
P
L
G
K
T
V
I
F
N
---------
K
R
P
F
R
V
I
G
V
V
S
D
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
59.55
12%
3
- C1 -
3IS6
2
?
A:
[45-199]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
I
Q
E
E
I
P
G
V
E
L
A
T
R
T
T
L
Y
G
T
S
K
M
I
L
E
D
-
N
K
T
Y
E
T
K
T
L
L
A
E
-
P
A
F
L
D
M
F
G
V
E
L
I
A
-
G
V
R
D
S
A
LR---
D
N
M
T
C
L
I
S
E
S
L
A
R
K
M
G
G
D
---
V
L
G
K
R
L
R
P
A
E
--
S
K
S
D
R
A
I
T
I
G
G
V
F
E
D
L
P
HNSSI
Q
A
D
M
L
L
P
I
T
W
M
P
A
E
S
L
N
N
WIG
N
D
R
Y
I
A
Y
V
R
L
R
P
G
V
S
P
E
S
L
D
E
A
L
L
E
M
Q
K
R
H
Q
D
M
E
V
F
R
K
A
G
V
E
L
H
Y
S
L
T
P
F
N
R
L
R
L
E
D
P
T
L
V
N
M
L
R
I
Q
------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
56.82
26%
130
- C3 -
1WHR
-
R3HD2_HUMAN
A:
[150-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
P
R
D
R
M
M
L
--
L
K
L
E
Q
E
I
L
E
F
I
N
D
N
N
N
Q
F
K
K
F
P
Q
M
T
S
Y
H
R
M
L
L
H
R
V
A
A
Y
F
G
M
D
H
N
V
D
Q
T
G
K
------------
A
V
I
I
N
K
T
S
N
T
R
I
P
E
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
56.77
15%
162
* C3 *
1D7M
-
CTXA_DICDI
A:
[243-343]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
A
N
R
L
A
G
L
E
N
S
L
---
E
S
E
K
V
S
--
R
-
E
Q
L
I
K
Q
K
D
Q
L
N
S
L
L
A
S
L
E
S
E
G
A
E
R
E
K
R
L
R
E
L
E
A
K
L
D
E
T
L
K
N
L
E
L
E
K
L
A
R
--
M
E
L
E
A
R
L
A
K
T
--
E
K
D
R
A
I
L
E
L
K
L
A
E
A
I
D
E
K
S
K
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
56.44
17%
246
- C3 -
2W83
2
JIP4_HUMAN
C:
[1-67]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
---
M
D
P
E
F
M
--
G
-
R
E
V
E
N
L
I
L
E
N
T
Q
L
L
E
T
K
N
A
L
N
I
V
K
N
D
L
I
A
K
--
V
D
E
L
T
C
E
K
D
V
L
Q
G
E
L
E
A
--
V
K
Q
A
K
L
K
L
E
E
--
K
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
55.75
25%
95
- C3 -
4AKF
-
?
A:
[153-244]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
K
I
A
L
Y
E
D
K
L
S
R
A
G
I
V
I
N
N
V
--------------------
D
D
I
I
N
L
T
K
S
V
K
D
L
E
K
L
D
K
A
L
N
S
I
P
T
E
L
K
G
A
K
G
E
Q
L
E
N
P
R
L
T
L
G
D
L
G
R
L
R
E
L
L
P
---
E
E
N
K
H
L
I
K
N
L
S
V
V
V
T
N
Q
T
K
H
E
L
E
R
Y
S
E
D
T
T
P
Q
Q
S
I
A
Q
V
V
Q
W
S
G
A
H
P
V
L
F
V
P
G
R
N
A
K
G
E
Y
I
A
D
G
G
I
L
D
N
M
P
E
I
E
G
L
D
R
E
E
V
L
C
V
K
A
E
A
G
T
A
F
E
D
R
V
N
K
A
K
Q
S
A
M
E
A
I
S
W
F
K
A
R
M
D
S
L
V
E
A
T
I
G
G
K
W
L
H
A
T
S
S
V
L
N
R
E
K
V
Y
Y
N
I
D
N
M
I
Y
I
N
T
G
E
V
T
T
T
N
T
S
P
T
P
E
Q
R
A
R
A
V
K
N
G
Y
D
Q
T
M
Q
L
L
D
S
H
K
Q
T
F
D
H
P
L
M
A
I
L
Y
I
G
H
D
K
L
K
D
A
L
I
D
E
K
S
E
K
E
I
F
E
A
S
A
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
N
D
G
D
Y
S
S
V
Q
N
Y
L
D
Q
I
E
D
I
L
T
V
D
A
K
M
D
D
I
Q
-
K
E
K
A
F
A
L
C
I
K
Q
V
N
F
L
S
-
E
G
K
L
E
T
Y
L
N
K
V
E
A
E
A
K
A
A
A
E
P
S
W
A
T
K
I
L
N
L
L
W
A
P
I
E
W
V
V
S
L
-----
F
K
G
P
A
Q
D
F
K
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.17
25%
103
- C3 -
4KYI
-
?
A:
[140-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
K
I
A
L
Y
E
D
K
L
S
R
A
G
I
V
I
N
N
V
--------------------
D
D
I
I
N
L
T
K
S
V
K
D
L
E
K
L
D
K
A
L
N
S
I
P
T
E
L
K
G
A
K
G
E
Q
L
E
N
P
R
L
T
L
G
D
L
G
R
L
R
E
L
L
P
---
E
E
N
K
H
L
I
K
N
L
S
V
V
V
T
N
Q
T
K
H
E
L
E
R
Y
S
E
D
T
T
P
Q
Q
S
I
A
Q
V
V
Q
W
S
G
A
H
P
V
L
F
V
P
G
R
N
A
K
G
E
Y
I
A
D
G
G
I
L
D
N
M
P
E
I
E
G
L
D
R
E
E
V
L
C
V
K
A
E
A
G
T
A
F
E
D
R
V
N
K
A
K
Q
S
A
M
E
A
I
S
W
F
K
A
R
M
D
S
L
V
T
S
S
V
L
N
R
E
K
V
Y
Y
N
I
D
N
M
I
Y
I
N
T
G
E
V
T
T
T
N
T
S
P
T
P
E
Q
R
A
R
A
V
K
N
G
Y
D
Q
T
M
Q
L
L
D
S
H
K
Q
T
F
D
H
P
L
M
A
I
L
Y
I
G
H
D
K
L
K
D
A
L
I
D
E
K
S
E
K
E
I
F
E
A
S
A
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
N
D
G
D
Y
S
S
V
Q
N
Y
L
D
Q
I
E
D
I
L
T
V
D
A
K
M
D
D
I
Q
K
E
K
A
F
A
L
C
I
K
Q
-
V
N
F
L
S
E
G
K
L
E
T
Y
L
N
K
V
-
E
A
E
A
K
A
A
A
E
P
S
W
A
T
K
I
L
N
L
L
W
A
P
I
E
W
V
V
S
L
F
K
G
P
A
Q
D
F
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
54.85
33%
144
- C1 -
1GWH
3
CATA_MICLU
A:
[244-306]
--------------------------------------------------------------------
D
F
H
R
Q
D
L
F
E
S
I
A
K
G
D
H
P
-
K
W
D
L
Y
I
Q
A
I
P
--
Y
E
E
G
-
K
T
Y
R
F
NP
F
D
L
T
---
K
T
I
S
Q
K
D
Y
P
R
I
K
V
G
T
L
T
L
------
N
R
N
P
E
N
H
F
A
Q
I
E
---
S
A
---
A
F
S
P
S
N
T
V
P
G
I
G
L
S
P
D
R
M
L
L
G
R
A
F
A
Y
H
D
A
Q
L
Y
R
V
G
A
H
V
N
Q
L
P
V
N
R
P
K
N
A
V
---
H
N
Y
A
F
E
G
Q
M
W
Y
-
D
H
T
G
D
R
S
T
Y
V
P
N
S
N
G
D
S
W
S
D
E
T
G
P
V
D
D
G
W
E
A
D
G
T
L
T
R
E
A
Q
A
L
R
A
D
D
---
D
D
F
G
Q
A
--
G
-
T
L
V
R
E
V
F
S
D
Q
E
R
D
D
F
V
E
T
V
A
G
A
L
K
G
V
R
Q
D
V
Q
A
R
A
F
E
Y
W
K
N
V
D
A
T
I
G
Q
R
I
--
E
D
E
V
K
R
H
E
G
D
--
G
I
P
G
V
E
A
G
G
E
A
R
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.71
33%
138
- C1 -
1HBZ
2
CATA_MICLU
A:
[239-301]
--------------------------------------------------------------------
D
F
H
R
Q
D
L
F
E
S
I
A
K
G
D
H
P
-
K
W
D
L
Y
I
Q
A
I
P
--
Y
E
E
G
-
K
T
Y
R
F
NP
F
D
L
T
---
K
T
I
S
Q
K
D
Y
P
R
I
K
V
G
T
L
T
L
------
N
R
N
P
K
N
H
F
A
Q
I
E
---
S
A
---
A
F
S
P
S
N
T
V
P
G
I
G
L
S
P
D
R
M
L
L
G
R
A
F
A
Y
H
D
A
Q
L
Y
R
V
G
A
H
V
N
Q
L
P
V
N
R
P
K
N
A
V
---
H
N
Y
A
F
E
G
Q
M
W
Y
-
D
H
T
G
D
R
S
T
Y
V
P
N
S
N
G
D
S
W
S
D
E
T
G
P
V
D
D
G
W
E
A
D
G
T
L
T
R
E
A
Q
A
L
R
A
D
D
---
D
D
F
G
Q
A
--
G
-
T
L
V
R
E
V
F
S
D
Q
E
R
D
D
F
V
E
T
V
A
G
A
L
K
G
V
R
Q
D
V
Q
A
R
A
F
E
Y
W
K
N
V
D
A
T
I
G
Q
R
I
--
E
D
E
V
K
R
H
E
G
D
--
G
I
P
G
V
E
A
G
G
E
A
R
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.44
33%
147
- C1 -
1GWE
2
CATA_MICLU
A:
[244-306]
--------------------------------------------------------------------
D
F
H
R
Q
D
L
F
E
S
I
A
K
G
D
H
P
-
K
W
D
L
Y
I
Q
A
I
P
--
Y
E
E
G
-
K
T
Y
R
F
NP
F
D
L
T
---
K
T
I
S
Q
K
D
Y
P
R
I
K
V
G
T
L
T
L
------
N
R
N
P
E
N
H
F
A
Q
I
E
---
S
A
---
A
F
S
P
S
N
T
V
P
G
I
G
L
S
P
D
R
M
L
L
G
R
A
F
A
Y
H
D
A
Q
L
Y
R
V
G
A
H
V
N
Q
L
P
V
N
R
P
K
N
A
V
---
H
N
Y
A
F
E
G
Q
M
W
Y
-
D
H
T
G
D
R
S
T
Y
V
P
N
S
N
G
D
S
W
S
D
E
T
G
P
V
D
D
G
W
E
A
D
G
T
L
T
R
E
A
Q
A
L
R
A
D
D
---
D
D
F
G
Q
A
--
G
-
T
L
V
R
E
V
F
S
D
Q
E
R
D
D
F
V
E
T
V
A
G
A
L
K
G
V
R
Q
D
V
Q
A
R
A
F
E
Y
W
K
N
V
D
A
T
I
G
Q
R
I
--
E
D
E
V
K
R
H
E
G
D
--
G
I
P
G
V
E
A
G
G
E
A
R
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
49.17
16%
285
- C3 -
1DH3
3
CREB1_MOUSE
A:
[1-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
E
V
R
L
M
K
N
R
E
A
A
R
E
S
R
R
K
K
K
---
E
Y
V
K
S
L
--
E
-
N
R
V
A
V
L
E
N
Q
N
K
T
L
I
E
E
L
K
A
L
K
D
L
Y
S
H
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
48.11
12%
220
- C3 -
1X8Y
-
LMNA_HUMAN
A:
[313-386]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
K
E
A
K
L
R
D
L
E
---
D
S
L
A
R
E
--
R
-
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
--
E
G
E
E
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
47.45
20%
288
- C3 -
1UII
-
GEMI_HUMAN
A:
[92-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
P
S
S
Q
Y
W
K
E
V
A
E
K
R
R
K
A
L
Y
E
A
L
K
E
N
E
K
L
---
H
K
E
I
E
Q
--
K
D
N
E
I
A
R
L
K
K
E
N
K
E
L
A
E
V
A
E
H
V
Q
Y
M
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
40.17
18%
297
- C3 -
1GK6
-
GCN4_YEAST (first)
A:
[355-409]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
--
K
-
Q
L
E
D
K
V
E
E
L
L
S
K
N
Y
H
L
E
N
E
V
A
R
L
K
K
L
V
G
D
L
-
L
N
V
K
M
A
L
D
I
E
I
A
T
Y
R
K
L
L
--
E
G
E
E
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.05
29%
187
* C2 *
4JRU
1
?
A:
[44-98]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
W
A
R
T
N
C
N
F
D
A
S
G
N
G
K
C
ETG
D
C
G
G
L
L
Q
C
T
A
Y
-
G
T
P
P
N
T
L
A
E
F
A
L
N
Q
F
S
N
L
D
F
F
D
I
S
L
V
D
G
F
N
V
P
M
A
F
N
P
T
S
N
G
C
T
R
G
I
---
S
C
T
A
D
I
--
V
-
G
E
C
P
A
A
L
K
T
T
G
G
C
N
N
P
C
T
V
F
K
T
D
E
Y
C
C
N
S
G
S
C
S
A
T
D
Y
S
R
F
F
K
T
R
C
P
D
A
Y
--
S
Y
P
K
D
D
Q
T
S
T
--
F
T
C
T
A
G
T
N
Y
E
V
V
F
C
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
39.26
14%
133
- C1 -
3IS6
1
?
A:
[88-149]
---------------------------------------------------------------------------------------------------------------------
L
D
M
F
G
V
E
L
I
A
---
G
V
R
D
S
ALR---
D
N
M
T
C
L
I
S
E
S
L
A
R
K
M
G
G
---
D
V
L
G
K
R
L
R
P
A
E
S
K
-----
S
D
R
A
I
T
I
G
G
V
F
E
D
L
P
H
N
S
S
I
Q
A
D
M
L
L
P
I
T
W
M
P
---
A
E
S
L
N
N
W
I
G
N
D
-
R
Y
I
A
Y
V
R
L
R
P
G
V
S
P
E
S
L
D
E
A
L
L
E
M
Q
K
R
H
Q
D
M
E
V
F
R
K
A
G
V
E
L
H
Y
S
L
T
---
P
F
N
R
L
R
--
L
-
E
D
P
T
L
V
N
M
L
R
I
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------