@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1126: (2015-12-05 )
MANTYDLISQRIEAQRQKLIAIDIVAVASSLGLNLKQGSGGHLYWDEHDSFHIYPQTNTFRWWSRSMGTNTIDLVQVIQEELTGKKPSFRETVNFLETGQFESVTVTPVVREPFKHYLAPYEHHNFDLGRQYLKEERGLSDETIDFALASGSMSSATLKKGDYFEPVIIFKSFAEDGRMIGGSLQGIVENKVQHPERGRLKQIMKHSDGLAGFHLDVGTPKRLVFSEAPIDLLSYYELHKESLQNVRLVAMDGVKKGVISRYTADLLTDGQYSQTMPRESIRGAIDAINQTTRILKNNPNMITIAVDNDEAGRNFIKELQEDGIPINVDLPPRKEHQSKMDWNNYLKQKKGLLKMPQTEGTQKAPEQVLEHEKMDRSQISSGSLEDDPQGSAKPVSKRDTFEQAVTSHPTFSYPLLQFSTEEAFVSNVRDGYHIASEEDIRNLNYYAPSLQQTANWYRDNLADRQVTYMLKGDKEIKALQVSFAKDKFAHLTGIRPIGKGLSAEKLLDDFAKGRGSYPNLTLSNGFNDKIQVLPMIQELSQSKSFVFTDLEEVQKMRNLKASHAIQSNNRSLVVALKTIDDVTFPSSLLRGKKNLNDDLIQKAKENEVLGVLSEKDGNITVLSVNDKYIQDGGQALKDMIKNGELEPLQMETIQRHVPHENAYPKDSDGDGLTDDEEIALGTNPFSSDSDGDGTPDNVEKANGTDPTNASDNEVTRQQEANKRDFTLSEMIKAKNTAALNQHLQDGIKQYFDSDTYKQYLEGMAHFNNYSPRNIQLIMSQFPEASMVASFQEWRKRNGSVKKGEKAIYIQAPVSVMKKDENGKPILNPETGEKETITYFKPVPVFDIKQVSPQEGKELNLPKAMGTIPEQLDKEYYQNVYRSLRDISQNNNKVPIRFRELGQEDGFYSPQTNEIVIKKGMSYERTLSTLIHEMAHSELHNKQSLTERFDGKLTRSTKELQAESIAYVVSSHLGFDTSQESFPYLASWSKEKDGLANLTAQLEIVQEEAKNLMERIDQQLSQYQTVTLNKETQQLTKQEMKKQTHPFYQSLAAAKTSRAQVTTQEKEASVKKDNRPTMP
Atome Classification :
(20 SA)
.....----------....10........20..------.......30........40..-----......50.......-------.60........70........80.--.......90........100......--.110.....--..120.--.......130.......140......--------------------------.150.--------------------------......160.......170.....-..180.......190...-...-------..200.-....--..210.....---..220....-...230.......240.......-250.......260.....---..270.......280.......290......---.300.......310.......320------...--...-..330.......340..---.....350.......360.-----------...------...370.......380-........390.......400.......410.......420.......430.--......----440.......450-........460.......470-.....-..---.480.......490.......500.......510..--.....520.......530........540...--.-...550.......560.....-..570.......580.......590.......600.......610.......620.......630.---......640.......650.......660.-......------670.......680....--...690.-------------......700.......710.......720.......730.......740.......750.......760.......770---........780.......790.......800.......810.......820.......830.......840.......850.......--860.......-----870.......880.......890.......900.....-----..910.......920----.........930.......----940.......950.......960.......970..------.....980...-...-.990........1000---.........----------1010.....----.1020......1030......1040......1050......-1060......1070.....------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
N
T
Y
----------
D
L
I
S
Q
R
I
E
A
Q
R
Q
K
L
I
-
A
I
------
D
I
V
A
V
A
S
S
LGLNLKQGSGG
H
L
-----
Y
WDEHD
S
F
H
I
Y
PQTN-------
T
F
R
W
WSRSMGT
N
T
I
D
L
V
Q
V
I
Q
E
EL--TGKKP
S
F
R
E
T
V
N
F
L
ETGQF
E
S
V
T
VT
P
--
V
V
R
E
P
F
K
H
Y--LAP-YE--HH
N
F
D
L
G
R
Q
Y
L
K
E
ERGLSDE
T
I
D
F
A
L--------------------------ASGSM--------------------------SSATLKKGDYFEP
V
I
I
F
K
S
F
AEDG-RMIG
G
S
L
Q
G
I
V
E
N
-KVQH-PE
R
-------
G
R
L
K
Q
I
-
M
K
HS--DG
L
A
G
F
H
LDV---GTP
K
R
L
V
FS-EAP
I
D
L
L
S
Y
Y
E
L
H
K
E
S
L
QN
V
R
L
V
-
A
M
D
G
V
K
K
G
V
I
S
R
Y
T
A
D
LL---TDGQYSQTM
P
R
E
S
I
R
G
A
I
D
A
I
N
Q
T
T
R
I
LKNN---P
N
M
I
T
I
A
VDN
D
E
A
G
R
N
F
I
K
E
L
Q
E-------DG
I
--
P
I
N-VDLPP
R
K
E
H
Q
SKM
D
W
N
N
---
Y
L
K
Q
K
KGLLKMPQTEGTQK-----------
A
P
E
------
Q
V
L
E
H
E
KM
D
R
S
QISS--GSLEDDPQGSAKPVS
K
R
D
T
F
E
Q
A
V
TSHPTFSYPLLQFS
T
E
E
A
F
V
S
N
VRD
G
Y
H--IA
S
E
E
D----IRNLNYYA
P
S
L
Q
--
Q
T
A
N
W
Y
R
DNLADR
Q
V
T
Y
M
LK--GDK
E
I
-
K
A
---
L
Q
V
SFAKD
K
F
A
H
LTGI
R
P
IGKGL
S
A
E
K
L
L
D
D
F
A
KGR--GSYP
N
L
T
LSNGFND
K
I
Q
-
V
L
P
M
I
Q
E
L
S
QSK
S
F
--
V
-
F
T
D
L
E
E
V
Q
K
M
R
N
L
K
A
S
H
A
IQS-NN
R
S
L
V
V
A
L
K
TIDDVTF
P
S
S
L
L
RGKKNL
N
D
D
L
I
Q
K
AKEN
E
V
L
G
V
L
SEKDG
N
I
T
V
L
SVN
D
K
Y
I
Q
D
G
G
---
Q
A
L
K
D
M
I
KNGELEP
L
Q
M
E
T
I
Q
R
HVPHENAY-PKDSDG------DGLTDDE
E
I
A
LGTNPFS--SDSDGDG-------------TPDNVEKANGTDPTNASD
N
E
V
T
R
Q
Q
EANKRDF
T
L
S
E
M
I
K
AK
N
T
A
A
L
N
Q
H
L
Q
D
G
I
K
Q
Y
FD
S
D
T
Y
K
Q
Y
L
E
G
M
A
HFNNYSP----
R
N
I
Q
L
I
M
S
QFP
E
A
S
M
V
A
S
F
Q
E
W
R
K
RNGSVKKG
E
K
A
I
Y
I
QA
P
V
S
V
MKKDENGKPILNPETGEK
E
T
I
T
Y
FKPV
P
V
F
D
I
KQVSPQEGKELN--LPKAMGT
I
P
E
-----
Q
L
D
K
E
Y
Y
Q
N
V
Y
R
S
L
R
D
I
SQNNNKV
P
I
R
F
R
ELGQEDGFY-----SPQT
N
E
I
V
I
KKGM------
S
Y
E
R
T
L
S
T
L
I
H
E
M
A
H
S
E
LH----
N
K
Q
S
L
T
E
R
FDGKLTR
S
T
K
E
L
Q
A
E
S
I
A
Y
V
V
S
S
HLGF------DTSQESFP
Y
L
A-SWS-KE-KD
G
L
A
N
L
T
A
Q
------
L
E
I
V
Q
E
E
A
K
----------
N
L
M
E
R
I
D
Q
Q
----
L
S
QY
Q
T
V
T
L
N
K
E
T
Q
Q
L
T
K
Q
E
M
K
K
QT
H
P
F
Y
Q
S
L
A
A
AKTSR
A
Q
-
V
T
T
Q
E
K
EASVKKDNRPTMP------------
49
Fugue
83.62
16%
11
- C2 -
4DDU
3
RGYR_THEMA
A:
[2-1103]
A
V
N
S
K
Y
H
HSCINCGG
L
N
T
D
E
R
N
E
R
G
L
P
C
E
V
-
C
L
PEDSPS
D
I
Y
R
A
L
L
E
R
K
-
T
L
K
E
Y
R
F
Y
H
E
-----
F
W
N
E
Y
E
D
F
R
S
F
F
K
K
K
F
G
K
D
L
T
G
Y
Q
R
L
W
A
K
R
I
V
Q
G
--
K
S
F
T
M
V
A
P
T
G
--
V
G
K
T
T
F
G
M
M
T
A
L
W
L
A
R
K
G
K
K
S
A
L
V
F
P
-----------------------
T
V
T
L
V
K
Q
T
L
E
R
L
Q
K
L
A
D
E
K
V
K
I
F
G
--------------------------
F
Y
S
S
M
--------------------------
K
K
E
--------
E
K
E
K
F
E
K
S
F
E
E
D
D
Y
H
I
L
V
F
S
T
Q
F
V
S
K
N
-
R
E
K
L
-
S
Q
K
RFD
F
V
F
V
D
D
V
D
A
V
-
L
K
A
S
--
R
N
I
D
T
L
L
M
M
V
---
G
I
P
E
E
I
I
R
K
A
F
S
T
I
K
Q
G
K
I
Y
E
R
P
K
N
L
K
P
G
I
L
V
V
S
S
A
T
A
K
P
R
G
I
R
P
L
L
F
R
D
L
L
NFT
V
G
R
L
V
S
V
A
R
N
I
T
H
V
R
I
S
S
R
S
K
E
K
L
V
E
L
L
E
I
F
---
R
D
G
I
L
I
F
A
Q
T
E
E
E
G
K
E
L
Y
E
Y
L
K
R
-------
F
K
F
--
N
V
G
-
E
T
W
S
E
F
E
K
N
F
E
D
F
K
V
G
K
IN
I
L
I
G
V
Q
A
Y
Y
G
K
L
T
R
G
V
D
L
P
E
RIK
Y
V
I
F
WG
T
P
S
M
R
------
F
S
L
E
L
D
K
A
P
R
F
V
L
A
R
---
V
L
K
E
M
G
L
I
K
A
Q
E
N
P
D
V
E
E
L
R
K
I
A
K
E
H
L
T
----------
Q
K
E
F
V
E
K
V
K
E
M
F
R
GV
V
V
K
D
E
D
L
E
L
I
I
P
D
V
Y
T
Y
I
Q
A
S
G
--
R
S
S
R
I
L
N
G
V
L
V
-
K
G
V
S
V
I
F
E
--
E
D
E
E
I
F
E
S
---
L
K
T
R
L
L
L
I
A
E
E
E
I
I
E
E
A
E
A
N
W
K
E
L
V
H
E
V
E
E
S
R
R
R
S
E
--
R
E
L
T
D
T
S
R
S
---------
L
L
I
I
V
E
S
P
T
K
A
E
T
L
--
S
R
F
L
G
R
A
S
S
R
K
E
R
N
I
I
V
H
E
A
V
T
---
G
E
G
V
I
L
F
T
A
T
R
G
H
V
--------------
Y
D
L
V
T
K
G
G
I
H
G
V
----
E
E
E
N
G
K
F
V
P
V
Y
N
S
L
K
R
C
R
D
C
G
-----------------
Y
Q
F
T
E
D
R
D
E
C
P
V
C
S
S
K
-
N
I
D
D
K
T
------
E
T
L
R
A
L
R
E
I
S
L
E
A
D
E
I
L
V
A
T
D
P
D
V
E
G
E
K
I
S
W
D
V
T
Q
Y
L
L
P
S
T
R
S
L
R
R
I
E
M
H
E
I
T
R
Y
G
F
K
K
A
R
E
S
V
R
F
V
D
F
N
L
V
K
A
Q
I
V
R
R
V
Q
D
R
W
I
G
F
E
L
S
G
K
L
Q
K
R
F
G
R
S
N
L
S
A
G
R
V
Q
S
T
V
L
G
W
I
V
E
----
R
E
E
E
Y
K
K
S
E
K
D
F
T
L
L
V
L
E
N
G
V
N
L
E
V
E
G
K
I
A
D
D
------
V
V
T
V
V
E
L
Q
E
A
E
E
E
K
N
P
L
P
P
Y
T
-
T
S
S
A
L
S
E
I
S
Q
K
L
R
L
G
V
Q
E
V
M
D
I
L
Q
D
L
F
E
K
G
F
I
T
Y
H
R
T
D
S
T
-----
R
I
S
L
E
G
Q
N
V
A
R
T
Y
L
R
K
I
G
K
E
D
I
F
M
G
R
S
W
S
T
E
G
A
H
E
A
I
R
PVKPI
D
A
R
E
L
E
E
M
I
E
E
G
L
IADLT
K
K
H
L
R
V
Y
E
L
I
F
N
R
F
L
A
S
Q
S
A
A
V
K
V
K
K
Q
I
V
T
V
D
V
D
G
K
R
M
G
I
E
Q
I
V
E
I
L
R
D
G
W
N
L
F
V
P
L
T
V
------
S
P
R
F
E
H
R
T
Y
K
I
-
K
E
K
-
K
F
Y
K
K
H
T
V
P
L
F
T
Q
------
A
S
I
V
E
E
M
K
K
R
GIGRPST
Y
A
K
I
V
E
V
L
F
R
R
GY
V
Y
E
D
K
Y
K
R
V
R
P
T
R
F
G
V
M
V
Y
S
Y
L
K
E
R
-----
Y
E
K
Y
V
T
E
E
T
T
R
R
L
-
E
E
I
M
D
K
V
E
R
G
E
E
D
Y
Q
A
T
L
R
L
L
Y
E
E
I
K
S
L
M
E
E
41
Fugue
72.53
18%
23
- C3 -
3UGM
-
PTHX1_XANOP
A:
[169-1048]
K
P
K
V
R
----------
E
L
V
A
H
I
V
A
L
S
Q
H
P
--------------------------------------------------------------------------------
A
A
L
--
G
T
V
A
V
T
Y
Q
H
I
I
T
A
L
A
T
----------------------------
H
--
E
D
I
V
G
V
G
K
Q
W
-------------------------------------------
S
G
A
R
--------------------------
A
L
E
A
L
L
T
D
A
--------------
G
-
E
L
R
G
P
P
L
Q
-----------
L
D
T
-------
G
Q
L
V
K
I
-
A
K
R
G
---
G
V
T
A
M
E
A
V
H
---
A
S
R
N
A
L
T
-----
P
L
N
L
-
T
P
A
Q
V
V
A
I
A
S
N
N
G
G
K
Q
-
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
---
T
P
A
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
M
Q
R
L
L
P
V
L
C
Q
A
HGL
P
P
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
-------
L
----------
L
P
V
L
C
Q
A
H
G
L
-----------
T
P
D
Q
V
V
A
I
A
S
H
G
G
G
K
Q
-----------
A
L
E
------
T
V
Q
R
L
L
P
V
L
C
Q
A
--
H
--
G
L
T
P
D
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
--
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
G
-----
G
G
K
Q
A
----
L
E
T
V
Q
R
L
L
P
V
L
C
--
Q
A
-----
H
G
L
T
P
D
Q
V
V
A
I
A
S
NG
G
K
Q
A
L
-
E
T
---
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
--
R
L
L
P
V
L
C
Q
T
H
G
L
T
-
P
A
Q
-
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
-
Q
Q
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
A
T
V
Q
R
L
L
---
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
G
-----
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
LT
P
D
Q
V
V
A
I
A
S
N
G
G
G
K
Q
A
-
L
E
T
V
Q
R
L
L
-------
P
V
L
C
Q
A
------
H
G
L
T
Q
V
Q
V
V
A
I
A
S
N
I
----------
G
-------------
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
-----------------
A
Q
V
V
A
I
A
S
H
--
D
G
G
K
Q
A
L
E
T
V
Q
R
L
--
L
P
V
L
C
Q
A
H
G
L
T
P
----
D
Q
V
V
A
I
A
S
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
G
L
T
-----------
Q
E
Q
V
V
A
I
A
S
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
G
G
G
K
Q
A
--
L
E
T
V
Q
R
L
L
P
V
LCQAH
G
L
T
P
A
Q
V
V
A
I
A
S
N
I
-
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
-----
L
A
Q
V
V
A
I
A
S
N
I
G
--------------------
G
K
Q
A
L
E
----
T
V
Q
R
L
L
P
V
L
C
Q
G
L
T
----
Q
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
------
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
-
L
T
-
P
D
Q
V
V
A
I
A
S
N
IGGKQ
A
L
E
T
V
Q
R
L
L
P
----------
V
L
C
Q
D
H
G
L
T
----
L
D
Q
V
V
A
I
A
S
N
G
G
K
Q
A
L
E
T
V
Q
----------
R
L
L
P
V
L
C
Q
D
H
G
-
L
T
P
D
Q
V
V
A
I
A
S
N
S
G
-----------------
27
HHSearch
64.97
21%
-45
* C4 *
2AU3
1
DNAG_AQUAE
A:
[3-338]
---------------------
M
S
S
D
I
D
E
L
R
R
E
I
------
D
I
V
D
V
I
S
E
Y
-
L
N
L
E
K
V
G
S
N
Y
R
T
N
CPF
H
P
D
D
T
P
S
F
Y
V
S
P
S
K
Q
-------
I
F
K
C
F
G
C
G
V
G
G
D
A
I
K
F
V
S
L
Y
E
--------
D
I
S
Y
F
E
A
A
L
E
L
A
K
R
Y
G
K
K
L
D
L
E
K
IS
K
D
E
K
V
Y
V
A
L
D
R
V
C
D
F
Y
R
E
S
L
L
K
N
R
E
A
S
E
Y
V
K
-
S
R
G
I
D
P
K
V
A
R
K
F
D
---------------------------
L
G
Y
A
PS
S
E
A
L
V
K
V
L
K
E
N
DL
L
E
A
Y
L
E
T
KNLL
S
P
T
K
G
V
Y
R
D
L
F
L
R
R
V
V
I
P
I
K
D
P
R
G
-
R
V
I
G
F
G
G
R
R
I
V
E
D
K
S
P
K
Y
-
I
N
S
-------
P
D
-
S
R
V
-
F
K
K
G
--
E
N
L
F
G
L
Y
E
A
K
E
Y
I
K
E
E
G
F
A
I
L
V
-
E
G
Y
F
D
L
L
R
L
F
S
E
G
I
---
R
--
N
V
V
-
A
P
L
G
T
A
---
L
T
Q
N
Q
A
N
L
---------------------
L
S
----------
K
F
---
T
K
K
V
Y
I
L
Y
D
G
D
D
A
G
R
K
A
M
K
S
A
I
P
L
L
L
S
---
A
G
V
--
E
V
Y
-
P
V
Y
L
P
-----
E
G
Y
D
P
D
E
---
F
I
K
E
F
G
K
E
E
L
R
R
L
I
N
S
S
G
E
-----------
L
F
E
------
T
L
I
K
T
A
R
E
N
L
E
E
K
T
R
--
E
F
R
Y
Y
L
G
F
I
S
D
G
V
R
R
F
A
L
A
S
E
F
H
T
K
Y
K
V
P
M
E
I
L
L
M
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
58.63
13%
21
- C3 -
4UI9
-
ANC2_HUMAN
N:
[15-730]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
G
Q
E
L
L
V
A
W
N
T
V
-------
S
T
E
--
E
L
R
-
A
A
V
E
V
L
R
G
H
V
L
E
E
W
F
V
E
---
V
L
Q
N
D
L
Q
A
N
I
S
P
E
F
W
N
A
I
S
-----------
Q
C
E
NSACLL
L
L
L
D
A
F
G
L
L
E
S
R
L
D
P
YL
R
S
L
E
L
L
E
K
W
T
R
L
G
L
L
M
G
T
G
A
Q
G
L
R
E
E
V
H
T
M
L
R
G
V
L
F
F
S
T
P
R
T
F
Q
E
M
I
Q
R
L
Y
G
--
C
F
L
R
V
Y
----
M
Q
S
K
R
K
G
D
P
E
L
E
GE
L
D
S
R
Y
A
R
R
R
Y
Y
R
L
L
Q
S
P
L
W
C
--
R
Q
A
L
E
-
Q
F
---
H
Q
L
S
Q
V
L
H
R
L
S
L
L
E
R
V
S
A
E
A
V
T
T
T
L
H
Q
V
T
R
E
R
M
E
D
R
CR
G
E
Y
E
R
-
S
F
L
R
E
F
H
K
W
I
E
R
V
V
G
W
L
G
K
V
F
T
L
R
R
W
--
R
-
C
H
V
Q
R
F
F
Y
R
I
Y
A
S
L
R
I
E
E
L
F
S
-
I
V
R
D
F
P
D
S
R
P
A
I
E
D
L
K
Y
C
L
E
R
T
D
Q
R
Q
Q
L
L
V
S
L
K
A
A
L
E
T
R
----
L
L
H
P
G
V
N
T
C
D
I
I
T
L
Y
I
S
A
I
K
-------
A
L
R
V
I
D
P
S
M
V
I
L
E
V
A
C
E
P
I
R
R
Y
L
R
T
R
E
-----
D
T
V
R
------
Q
I
V
A
G
L
T
D
L
A
V
E
L
S
K
E
P
--
E
D
W
-----------------
V
P
D
P
V
D
A
D
P
G
K
S
S
S
K
-------------
R
R
S
S
D
I
I
S
L
L
V
S
I
Y
----------
G
S
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
L
L
H
Q
F
S
F
S
P
EREI
R
N
V
E
L
L
K
L
R
F
G
E
A
P
M
-------
H
F
C
E
V
M
L
K
D
M
A
D
S
R
R
I
N
A
N
I
R
E
E
D
E
K
R
P
A
E
E
--
Q
P
P
F
G
V
Y
A
V
I
L
S
S
E
F
W
P
--------
P
F
K
D
E
K
L
E
--
V
P
E
D
I
R
A
A
L
E
-----
A
Y
C
K
K
Y
E
Q
L
--
K
A
M
R
T
L
S
W
K
--------
H
T
L
G
L
V
T
M
D
V
-----
E
L
A
D
R
T
L
S
V
----------
A
V
T
P
V
Q
A
V
I
L
L
Y
F
Q
D
Q
A
S
W
----
T
L
E
E
L
S
K
A
V
K
M
P
V
A
L
L
R
R
R
M
S
V
W
L
Q
Q
G
V
L
R
-----------
E
E
P
P
G
T
F
S
V
I
E
-
E
E
R
P
Q
D
-
R
D
N
M
V
L
I
------------------------------------------------------------------------------------------------------------------
29
HHSearch
57.98
23%
-17
- C4 -
1DD9
1
DNAG_ECOLI
A:
[42-259]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
A
R
Q
Y
L
E
-
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
APPGWD
N
V
L
K
R
FGGN
P
E
N
R
Q
S
L
I
D
A
G
M
L
--------------------------
V
T
N
--
R
S
Y
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
-
R
V
I
G
F
G
G
R
V
L
G
N
D
-
T
P
K
Y
-
L
N
S
-------
P
E
-
T
D
I
-
F
H
K
G
--
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
-
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
-----
Y
A
V
-
A
S
L
G
-
S
---
T
T
A
D
H
I
Q
L
---------------------
L
F
----------
R
A
---
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
LPYMT
D
G
R
--
Q
L
R
-
F
M
F
L
P
-----
D
G
E
D
P
D
T
---
L
V
R
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
-----------
L
S
A
------
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
--
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
55.64
17%
16
- C1 -
4CR2
-
RPN1_YEAST
Z:
[49-993]
----
L
----------
E
L
L
V
E
R
L
K
E
D
D
S
S
L
Y
-
E
A
------
S
L
N
A
L
K
E
S
I
K
N
S
T
S
S
M
T
A
V
P
K
-----
P
L
K
F
L
R
P
T
Y
P
D
L
C
S
I
-------
Y
D
K
W
T
D
P
N
L
K
S
S
L
A
D
V
L
S
I
L
A
M
T
Y
SE
N
G
K
H
D
S
L
R
Y
R
L
L
S
D
V
S
D
--------------------------
F
E
--
G
W
G
H
E
Y
I
R
H
L
A
L
E
I
G
E
V
Y
N
D
Q
V
E
K
D
A
--------------------------
E
D
E
T
S
--------------------------
S
D
G
S
K
S
D
G
S
A
A
T
S
-----
G
F
E
F
S
K
-
E
D
T
L
R
L
C
L
D
I
V
P
Y
-
F
L
K
H
N
G
E
E
-------
D
A
V
D
L
L
-
L
E
I
E
S
I
D
K
L
P
Q
F
V
D
E
N
---
T
F
Q
R
V
C
Q
Y
M
-
V
A
C
V
P
L
L
P
P
P
E
-
D
V
A
F
L
K
T
A
Y
S
I
-
Y
L
S
---
Q
N
E
L
T
D
A
I
A
L
A
V
---
R
L
G
------
E
E
D
M
I
R
S
V
F
D
A
--------
T
S
D
---
P
V
M
H
K
Q
L
A
Y
I
L
A
A
---
Q
K
T
S
F
E
Y
-------
E
G
V
--
Q
D
I
-
I
G
N
G
K
L
S
E
H
------
F
L
---
Y
L
A
K
E
L
N
L
T
------
G
P
K
V
-----------
P
E
D
------
I
Y
K
S
H
L
D
N
S
K
S
V
F
S
S
--
A
G
L
--------------
D
S
A
Q
Q
N
L
A
S
S
F
V
N
G
F
L
N
L
G
Y
C
N
D
K
L
I
V
D
N
D
N
W
V
Y
K
--
T
K
G
--------
D
G
M
T
S
A
V
A
S
I
G
--
S
I
Y
Q
W
N
L
D
G
L
Q
Q
L
D
-
K
Y
L
Y
V
--
D
E
P
E
V
-
K
A
G
A
L
L
G
I
G
I
S
A
S
G
-
V
H
D
G
E
V
E
P
A
L
L
L
L
Q
D
Y
V
T
N
P
D
T
K
I
S
S
--
A
A
I
L
G
L
G
I
A
F
A
G
S
K
N
D
E
-
V
L
G
L
L
L
P
I
A
A
S
T
D
L
--
P
-
I
E
T
A
A
----
M
A
S
L
A
L
A
H
V
F
V
G
-
T
C
N
------
G
D
I
T
T
S
I
M
D
N
F
L
E
R
T
A
I
E
L
K
T
D
W
V
R
F
L
A
L
--
A
L
G
I
L
---------------
Y
M
G
Q
G
E
---
Q
V
D
D
V
L
E
T
I
S
A
I
E
------------------------------
H
P
M
T
S
A
I
E
V
L
V
G
S
C
A
Y
T
--
G
T
G
D
-------------------------------------
V
L
L
I
Q
D
L
L
H
R
L
T
L
A
Y
A
V
L
G
I
A
L
I
A
L
G
-----------
E
D
I
G
K
E
M
S
L
R
H
F
G
H
L
M
H
Y
G
N
----
E
H
I
R
R
M
V
---
P
L
A
M
G
I
V
S
-----------------------------------
V
S
D
P
Q
M
K
V
F
D
T
L
T
R
F
S
H
---------
D
A
D
L
E
V
S
M
N
--
S
I
F
A
M
G
L
C
G
----------------------
A
G
T
N
N
A
R
L
A
Q
L
L
R
Q
L
A
S
---
Y
Y
-----
S
R
E
------
Q
D
A
L
------
F
I
T
R
L
A
Q
G
L
L
H
L
-----------
G
K
G
T
M
T
--
M
D
--
V
F
N
D
A
H
V
L
N
K
V
T
L
A
S
I
L
T
T
A
V
G
L
VSPSFM
L
K
H
H
Q
L
F
Y
M
L
N
-
A
G
I
-
R
P
-
K
F
--------------
I
L
A
L
N
D
E
G
--------------
E
P
I
K
V
N
----
V
R
V
G
Q
P
V
L
L
N
H
G
------
E
R
A
E
L
E
T
D
E
Y
I
-----
S
Y
T
S
H
I
E
G
V
V
I
L
K
K
N
P
D
Y
R
E
E
E
-----------------
30
HHSearch
50.21
22%
-17
- C4 -
1Q57
-
PRIM_BPT7
A:
[73-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
N
G
R
Y
S
A
L
T
-
A
R
G
I
S
K
E
T
C
Q
K
A
-----------------------------
G
Y
W
--------------------------
I
A
K
V
D
-----
G
V
M
Y
Q
V
A
D
Y
R
D
Q
N
G
-
N
I
V
S
Q
K
V
R
D
K
D
K
------------------
N
F
K
T
T
G
S
H
K
S
--
D
A
L
F
G
K
H
L
W
N
----
G
G
K
K
I
V
V
T
-
E
G
E
I
D
M
L
T
V
M
E
L
Q
D
C
---
K
Y
P
V
V
-
S
L
G
H
G
A
S
A
A
K
-
K
T
C
A
A
---------------------
N
Y
E
--------
Y
F
D
Q
---
F
E
Q
I
I
L
M
F
D
M
D
E
A
G
R
K
A
V
E
E
A
A
Q
-------
V
L
P
AG
K
V
R
-
V
A
V
L
P
------
C
K
D
A
N
E
---
C
H
L
N
G
H
D
R
E
I
M
E
Q
V
W
N
A
G
P
-----------
W
I
P
------
D
G
V
V
S
A
L
S
L
R
E
R
I
R
E
--
H
L
S
S
E
E
S
V
G
L
L
F
S
G
C
T
G
I
N
D
K
T
L
G
A
R
G
G
E
V
I
M
V
T
S
G
S
G
M
V
M
S
T
F
V
R
Q
Q
A
L
Q
W
--
G
T
A
M
G
K
----
K
V
G
L
A
M
L
E
E
S
V
E
--
E
T
A
E
D
L
I
G
L
H
N
R
V
R
L
R
Q
S
D
S
--
L
K
R
E
I
-
I
E
---
N
G
K
F
D
Q
W
F
D
E
L
F
G
N
D
T
F
H
L
Y
D
S
F
E
T
D
R
L
L
A
K
L
A
Y
M
R
--
S
G
L
G
C
D
V
I
I
L
D
H
I
S
I
V
V
-
S
A
S
G
E
S
D
E
R
K
M
I
D
N
--
L
-
M
T
K
L
K
G
F
A
K
S
T
G
V
V
L
V
V
I
C
H
L
-
K
N
P
D
K
G
K
A
H
E
E
G
R
P
V
S
I
T
D
L
R
G
S
G
A
L
R
Q
L
S
D
T
I
I
A
L
E
R
N
Q
Q
G
D
M
P
N
L
V
L
V
R
I
L
K
C
R
F
T
G
D
T
G
I
A
G
Y
---
M
E
Y
N
K
E
T
G
W
L
E
P
S
S
Y
S
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
49.86
18%
-9
- C4 -
1NUI
3
PRIM_BPT7
A:
[20-248]
------------------------------------------------------------------
C
G
S
S
D
G
N
S
L
F
S
-
D
G
-------
H
T
F
C
Y
V
C
E
K
W
T
A
----
T
K
E
R
A
-------------------
S
K
R
K
P
S
--
G
G
K
P
--
G
T
Y
N
V
W
N
----
F
G
--
E
------
S
N
G
R
Y
S
A
L
T
-
A
R
G
I
S
K
E
T
C
Q
K
A
-----------------------------
G
Y
W
--------------------------
I
A
K
V
-----
D
G
V
M
Y
Q
V
A
D
Y
R
D
Q
N
G
-
N
I
V
S
Q
K
V
R
D
K
D
-----
K
-------------
N
F
K
T
T
G
S
H
K
S
--
D
A
L
F
G
K
H
L
W
----
N
G
G
K
K
I
V
V
T
-
E
G
E
I
D
M
L
T
V
M
E
L
Q
D
C
---
K
Y
P
V
V
-
S
L
G
H
G
A
S
A
----
A
K
K
T
C
A
---
A
---------------
N
Y
E
--------
Y
F
D
Q
---
F
E
Q
I
I
L
M
F
D
M
D
E
A
G
R
K
A
V
E
E
A
A
Q
-------
V
L
P
AG
K
V
R
-
V
A
V
L
P
------
C
K
D
A
N
E
---
C
H
L
N
G
H
D
R
E
I
M
E
Q
V
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
47.70
31%
269
- C6 -
4ODN
4
?
A:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
V
Q
V
V
P
L
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
46.83
31%
276
- C6 -
4ODL
2
?
A:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
V
Q
V
V
P
L
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
46.12
31%
266
* C6 *
4ODM
3
?
B:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
46.05
14%
54
- C4 -
2FCJ
-
?
A:
[4-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
K
V
I
I
V
-
E
G
R
S
D
K
Q
K
V
A
A
V
L
N
---
E
P
V
V
I
V
-
C
T
N
G
T
----
I
S
D
A
R
L
E
E
L
---------------------
A
--------
D
E
L
E
---
G
Y
D
V
Y
L
L
A
D
A
D
E
A
G
E
K
L
R
R
Q
F
R
R
-------
M
F
P
--
E
A
E
H
L
Y
I
D
R
-----
A
Y
R
E
V
A
A
---
A
P
I
W
H
L
A
Q
V
L
L
R
A
R
F
D
V
R
I
-----------
E
S
L
------
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
45.87
31%
265
- C6 -
4ODO
3
?
A:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
V
Q
V
V
P
L
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
45.28
31%
268
- C6 -
4ODM
2
?
C:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
L
V
P
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
45.02
31%
277
- C6 -
4ODO
3
?
B:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
S
G
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
44.42
31%
265
- C6 -
4ODM
3
?
D:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
43.92
36%
132
- C5 -
3DTK
3
IRRE_DEIDV
A:
[64-107]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
L
T
F
M
P
M
G
Q
R
D
G
A
Y
-----
D
P
E
H
H
V
I
L
I
N
S
Q
V
------
R
P
E
R
Q
R
F
T
L
A
H
E
I
S
H
A
L
L
L
----
G
D
D
D
L
L
S
D
L
H
D
E
Y
E
G
D
R
L
E
Q
V
I
E
T
L
C
N
V
G
A
A
A
L
L
M
------
P
A
E
L
I
D
D
L
L
T
R
-
F
G
P
-
T
G
-
R
A
L
A
E
L
A
R
R
A
------
D
V
S
A
T
S
A
L
Y
----------
A
L
A
E
R
T
A
P
P
----
V
I
Y
A
V
C
A
L
S
R
A
K
E
L
T
V
R
A
S
S
A
S
A
G
V
K
Y
S
L
S
A
G
T
P
V
P
D
D
H
P
A
-
A
L
A
L
D
T
R
L
P
L
A
Q
D
S
Y
V
P
F
R
------------
26
PsiBlast_CBE
43.85
31%
289
- C6 -
4ODL
2
?
B:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
43.58
31%
258
- C6 -
4ODM
2
?
A:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
V
Q
V
V
P
L
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
42.24
31%
272
- C6 -
4ODO
5
?
C:
[51-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
F
Q
A
H
V
P
A
E
K
A
Y
G
P
H
D
P
E
G
VQVVPL
S
A
F
P
E
D
A
E
V
V
P
G
A
Q
F
Y
A
--
Q
D
M
E
G
N
P
-------------
M
P
L
T
V
V
A
V
E
G
E
E
V
T
V
D
F
N
H
P
L
A
G
K
D
L
D
F
Q
V
E
V
V
K
V
R
E
A
T
P
E
E
L
L
H
G
H
A
H
P
S
G
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------