@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1169: (2015-12-05 )
MKFEKRQVYYVVITFAICYAIQAYWGAVSNILTTLHKAIFPFLMGAGIAYIINIVMSVYERLYIKLFKGSRLLMAIKRSVSMILSYATFIGLIVWLFSIVIPDLISSLSSLLVIDTGALAKLVNNLNENKQISEALNYMGTDKDLVSTLSGYSQQILKQVLSVLTNLLTSVSSIAATLLNVFVSFIFSIYVLANKEQLGRQFNLLIDTYLGSTGKTFHYVRHILHQRFHGFFVSQTLEAMILGSLTVIGMLIFQFPYALTVGVLVAFTALIPVVGAYIGVTIGFILIATESLTEAFLFVLFLILLQQFEGNVIYPKVVGGSIGLPSMWVLTAITIGGALWGILGMLLAVPVAATIYQIVKDHIIKRQTLRNRARTYR
Atome Classification :
(20 SA)
------------......---...10........20----........30........40--...----.....50........60........70........80--........90........100...---......110.......120.......130......-.140......------.--150-........160.........170.......180.......190...-....200.......210.......220..--.....230.......240-.......250.......260.----......270.......280.......290....------...300.......310.......320------.........330.....--..340..--......350--........360.......370.....----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MKF
E
K
R
---
Q
V
Y
Y
V
V
I
T
F
A
I
C
Y
A
I
----
Q
A
Y
W
G
A
V
S
N
I
L
T
T
L
H
K
A
I
F
P
--
F
L
M
----
G
A
G
I
A
Y
I
I
N
I
V
M
S
V
Y
E
R
L
Y
I
K
LFKG
S
R
L
L
M
A
I
K
R
S
V
S
--
M
I
L
S
Y
A
T
F
I
G
L
I
V
W
L
F
S
I
V
--
I
P
D
---
L
I
S
S
L
S
S
L
L
V
ID
T
G
A
L
A
K
L
V
N
NLNE
N
K
Q
I
S
E
A
L
N
Y-MGT
D
K
D
L
V
S
T
------
L
--
S
G
--
Y
S
Q
Q
I
L
K
Q
V
--
L
S
V
L
T
N
L
L
T
S
V
S
S
I
A
A
T
L
L
N
V
F
V
S
F
I
F
S
I
Y
VLA
N
K
-
E
Q
L
G
R
Q
F
N
L
L
I
D
TYLGSTG
K
T
F
H
Y
V
R
H
I
L
--
H
Q
R
F
H
G
F
F
V
S
Q
T
L
E
A
M
I
L
-
G
S
L
T
V
I
G
M
L
I
F
Q
F
P
Y
A
L
T
V
G
V
----
L
V
A
F
T
A
L
I
P
V
V
G
A
Y
I
G
V
T
I
G
F
I
L
I
A
T
E
S
L
T
E
A
F
------
L
F
V
L
F
L
I
L
L
Q
QFEG
N
V
I
Y
P
K
VVGG--------SIGL
P
S
M
W
V
L
T
A
I
T
I
G
G
--
A
L
W
G
-
I
L
--
G
M
L
L
A
V
P
V
---
A
A
T
I
Y
Q
I
V
K
D
H
I
I
K
R
Q
T
L
R
N
R
ARTYR----------
25
Fugue
89.55
17%
-165
- C2 -
4FDT
2
?
A:
[21-425]
MQT
K
I
Q
K
Y
A
GTA
M
P
Y
P
N
R
TDG
M
T
P
F
Y
I
N
H
L
G
R
H
G
A
R
FPTS
R
K
A
L
D
K
V
E
K
V
L
V
S
A
Q
Q
E
N
G
L
--
T
S
E
----
G
M
A
L
L
S
M
I
R
R
L
S
R
L
F
D
G
Q
W
G
K
L
---
S
K
L
G
E
T
E
Q
E
G
I
A
G
R
M
I
R
N
Y
P
Q
L
F
S
N
S
A
K
I
E
A
I
A
T
Y
V
P
R
---
S
I
N
S
M
D
A
F
L
S
C
M
I
R
H
N
P
A
L
Q
V
Q
R
S
E
G
K
Q
Y
N
H
I
L
R
F
-
F
D
L
N
K
S
Y
V
N
Y
K
E
KG
D
W
L
--
P
I
--
Y
K
A
F
V
H
K
K
I
SP
V
P
I
M
K
K
F
L
L
N
P
E
Q
Y
L
D
K
E
A
E
E
F
V
M
A
L
F
S
V
A
A
I
L
P
D
------------------
T
S
I
P
L
N
L
E
D
L
F
T
--
L
D
E
W
H
R
Y
W
Q
T
Q
N
L
R
Q
Y
M
S
K
S
S
A
P
V
G
K
M
L
P
V
A
I
A
W
P
L
L
S
E
F
----
I
R
S
A
Q
E
V
I
S
G
K
S
D
Y
-
Q
A
N
F
R
F
A
H
------
A
E
T
V
------
I
P
F
V
S
L
M
G
I
E
K
T
D
V
Q
V
C
R
P
D
S
V
S
V
YWKDYEIS
P
M
A
A
N
V
Q
W
L
F
Y
R
D
R
D
Q
R
--
I
W
V
K
-
I
L
L
N
E
E
A
A
A
L
P
I
STA
C
F
P
Y
Y
S
W
E
K
T
R
I
F
F
N
Q
R
I
E
M
A
K
K
T
L
S
V
F
N-------
26
Fugue
66.42
11%
-141
- C1 -
1E94
1
HSLU_ECOLI
E:
[7-449]
--HSEMTPREIV
S
E
L
D
K
H
---
I
I
G
Q
D
N
A
K
R
S
V
A
I
A
L
----
R
N
R
W
R
R
M
-
Q
L
N
E
E
L
R
H
E
V
T
P
KN
I
L
M
IGPT
G
V
G
K
T
E
I
A
R
R
L
A
K
L
A
N
A
P
F
I
K
V
E
-
A
T
K
F
T
E
V
G
Y
V
G
K
E
--
V
D
S
I
I
R
D
L
T
D
A
A
V
K
M
V
R
V
Q
--
A
I
E
---
K
N
R
Y
R
A
E
E
L
A
E
E
R
I
L
D
V
L
I
P
P
A
K
N
N
W
G
Q
T
E
Q
Q
Q
E
P
-
S
A
A
R
Q
A
F
R
K
K
------
L
RE
G
Q
--
L
D
D
K
E
I
E
K
Q
--
K
A
R
K
L
K
I
K
D
A
M
K
L
L
I
E
E
E
A
A
K
L
V
N
P
E
E
L
K
Q
D
A
I
D
A
V
E
Q
H
G
I
V
F
I
D
E
I
D
K
I
C
K
R
G
E
S
S
----------
G
P
D
V
S
R
E
G
V
Q
R
D
L
L
P
L
V
E
-
G
C
T
V
S
T
K
H
G
M
V
K
T
D
H
I
L
F
I
A
S
GAFQ
I
A
K
P
S
D
L
I
P
E
L
Q
G
R
L
P
I
R
V
E
L
Q
A
L
T
T
S
D
F
E
R
I
L
TEPNAS
I
T
V
Q
Y
K
A
L
M
A
T
E
G
V
N
I
E
F
T
D
S
G
I
K
--------
R
I
A
E
A
A
W
Q
V
N
E
S
T
E
N
I
G
AR
R
L
H
T
-
V
L
--
E
R
L
M
E
E
I
S
---
Y
D
A
S
D
L
S
G
Q
N
I
T
I
D
A
D
Y
V
S
K
H
L
D
A
L
V
ADEDLSRFIL
8
PsiBlast_PDB
56.47
27%
-97
- C3 -
4WYQ
-
DICER_HUMAN
A:
[7-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
E
A
L
N
F
-
I
N
D
C
N
I
S
------------
E
R
--
D
S
T
L
I
S
K
Q
I
--
L
S
D
C
R
A
V
L
V
V
L
G
P
W
C
A
D
K
V
A
G
M
M
V
R
E
L
Q
K
Y
I
K
H
E
Q
-
E
E
L
H
R
K
F
L
L
F
T
D
T
F
L
R
K
I
H
A
L
C
E
E
H
F
S
P
A
--
S
L
D
L
K
F
V
T
P
K
V
I
K
L
L
E
I
L
-
R
K
Y
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
49.10
13%
-89
- C3 -
3WPA
1
?
A:
[65-410]
------------
N
V
A
Q
G
N
---
Q
T
N
-------
V
G
D
A
L
----
T
A
L
D
N
A
I
N
T
A
A
T
T
S
K
S
T
V
-----------
S
N
G
Q
N
I
V
V
S
K
S
K
N
A
D
G
S
D
N
Y
E
V
S
T
A
K
D
L
T
V
D
S
V
K
A
G
D
--
T
V
L
N
N
A
---
G
I
T
I
G
N
N
A
V
V
--
L
N
N
T
G
L
T
I
S
G
G
P
S
V
T
L
A
G
I
D
A
G
N
K
T
I
Q
N
V
A
N
A
V
N
A
T
D
A
V
N
--
K
G
Q
L
D
S
A
I
N
N
------
V
--
N
N
--
N
V
N
E
L
A
N
N
A
--
V
K
Y
D
D
A
S
K
D
K
I
T
L
G
G
G
A
T
G
T
T
I
T
N
V
K
D
G
T
V
A
Q
G
S
K
-
D
A
V
N
G
G
Q
L
W
N
V
Q
Q
Q
V
D
Q
N
T
T
D
I
S
N
I
K
N
D
I
--
N
N
G
T
V
G
L
V
Q
Q
A
G
K
D
A
P
V
T
-
V
A
K
D
T
G
G
T
T
V
---
N
V
A
G
T
D
G
N
----
R
V
V
T
G
V
K
E
G
A
V
N
A
T
----------
S
K
D
A
V
N
G
S
Q
------
L
N
T
T
N
Q
A
V
V
N
Y
L
G
G
G
A
G
Y
D
N
I
-
T
G
--------
S
F
T
A
P
S
------
Y
T
V
G
D
--
S
K
Y
N
N
V
G
--
G
A
I
D
A
L
N
Q
---
A
D
Q
A
L
N
S
K
I
D
N
V
S
N
K
L
D
N
A
F
R
I
T
N
N
R
I---------
18
Fugue
49.06
20%
-26
- C3 -
1V66
-
PIAS1_HUMAN
A:
[1-65]
------------------------------------------------------------------------------------------------------------------------------------------------
M
A
D
S
A
E
L
K
Q
M
V
M
S
L
R
-
V
S
E
L
Q
V
L
L
G
Y
-
A
G
R
N
K
--------------
H
G
--
R
K
H
E
L
L
T
K
A
--
L
H
L
L
K
A
G
C
S
P
A
V
Q
M
K
I
K
E
L
Y
R
R
R
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.30
24%
-104
- C3 -
3QOA
1
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
T
Q
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
3
PsiBlast_PDB
47.71
24%
-104
- C3 -
3QU8
1
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
TQ
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
4
PsiBlast_PDB
47.36
24%
-93
- C3 -
3UA5
2
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
T
Q
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
1
PsiBlast_PDB
46.91
24%
-98
- C3 -
3IBD
2
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
T
Q
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
7
PsiBlast_PDB
46.71
24%
-101
- C3 -
4RRT
3
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
T
Q
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
--------------------------------------------------
5
PsiBlast_PDB
46.31
24%
-102
- C3 -
4I91
2
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
TQ
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
6
PsiBlast_PDB
46.28
24%
-101
- C3 -
4RQL
3
CP2B6_HUMAN
A:
[348-438]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
H
I
V
T
Q
H
T
S
F
R
G
Y
I
I
P
K
D
T
E
V
F
L
I
-
L
S
T
A
L
H
D
P
H
Y
F
E
K
P
D
A
F
N
P
D
H
----
F
L
D
A
N
G
A
L
K
K
T
E
A
F
I
P
F
S
L
G
K
R
I
C
L
G
E
G
I
A
R
A
E
------
L
F
L
F
F
T
T
I
L
Q
N
F
S
M
A
S
P
V
A
P
E
D
I
D
--------
L
T
P
Q
E
C
G
V
G
K
I
P
P
T
Y
Q
I
--
R
F
L
P
-
R
H
-------------------------------------------------
22
Fugue
35.25
23%
242
- C3 -
3BPQ
-
RELB3_METJA
A:
[8-48]
-------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
F
I
S
R
K
E
Y
E
K
I
E
E
I
L
D
--
I
G
L
A
K
A
M
E
E
T
------
K
--
D
D
E
L
L
T
Y
D
E
I
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
35.08
31%
64
- C3 -
4RPA
-
PPAC_STAAM
A:
[250-309]
--------------------------------------------------------------------------------------------------------------------------
L
F
V
L
V
--
V
T
D
---
I
I
N
S
D
S
K
I
L
V
V
--
G
A
---------
E
K
D
K
V
G
E
A
F
N
V
Q
L
E
D
D
M
A
F
L
S
G
------
V
--
V
S
--
R
K
K
Q
I
V
P
Q
I
--
T
E
A
L
T
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
33.83
14%
136
- C3 -
2KK9
-
A:
[1-55]
-------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
L
R
R
D
L
D
A
S
R
E
A
K
K
Q
L
E
A
-
E
Q
Q
K
L
E
E
Q
N
K
------
I
--
S
E
--
A
S
R
K
G
L
R
R
D
--
L
D
A
S
R
E
A
K
K
Q
V
E
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
32.94
14%
117
- C3 -
3X0U
-
?
A:
[41-61]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
F
G
L
S
N
I
P
Y
A
G
G
F
L
S
T
L
W
N
I
F
W
P
N
T
P
N
E
P
D
I
E
------
N
I
W
E
Q
L
R
D
R
I
Q
D
L
V
D
E
S
I
I
D
A
I
N
G
--------
I
L
D
S
K
I
K
E
T
R
D
K
I
Q
D
I
N
--
E
T
I
E
-
N
F
--
G
Y
A
A
A
K
D
D
---
Y
I
G
L
V
T
H
Y
L
I
G
L
E
E
N
F
K
R
E
L
D
G
D
E
W
L
----------
27
Fugue
31.89
18%
271
* C3 *
2KJ4
-
?
B:
[99-130]
--------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
V
E
K
L
T
A
D
A
E
L
Q
R
L
K
N
E
-
R
H
E
E
A
E
L
E
R
L
------
K
--
S
E
--
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
29.04
18%
165
- C3 -
3AJF
2
VSR_RHBVC
A:
[41-74]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
I
R
K
P
D
D
---
P
E
N
L
S
V
F
L
K
S
A
I
W
M
L
S
H
K
R
D
L
P
G
H
Y
R
----------
13
HHSearch
26.90
4%
201
- C3 -
3ZE3
2
KDGL_ECOLI
A:
[102-127]
-----------------------------------------------------------------------------------------------------
A
K
D
L
G
--
S
A
A
V
L
I
A
I
I
D
A
V
I
T
W
A
I
L
L
--
W
S
H
---
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
26.02
22%
410
- C3 -
3WU2
-
PSBJ_THEVL
J:
[12-29]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
T
V
A
G
M
--
G
V
I
V
-
I
V
--
G
L
F
F
Y
G
A
Y
---
A
G
L
G
S
S
L
-----------------------------