@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1229: (2015-12-06 )
MAKQDITVTNYGDDAIQVLEGLDAVRKRPGMYIGSTDGTGLHHLVWEIVDNAVDEALSGFGNRIDVIINKDGSITVTDHGRGMPTGMHAMGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEIIRDGAIYRQRFENGGKPVTTLKKIGTAPKSKSGTSVSFMPDQSVFSTIDFKFNTIAERLKESAFLLKNVTLTLTDNRSEEAEHLEFHYENGVQDFVEYLNEDKETLTPIMFFEGEEQEFHIEVALQYNDGFSDNILSFVNNVRTKDGGTHETGLKSAITKSMNDYARKTGLLKEKDKNLEGSDYREGLSAILSILVPEEHLQFEGQTKDKLGSPLARPIVDGIVSEKLTYFLMENGDLASNLIRKAIKARDAREAARKARDESRNGKKSKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNTAKAKMADIIKNEEINTMIHTIGAGVGPDFNIDDINYDKVIIMTDADTDGAHIQTLLLTFFYRYMRPLVEEGHVYIALPPLYKMSKGKGKKEIVEYAWTDIELEELRQKFGKGSLLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGDKVPPRRQWIEDNVKFTLEENTVF
Atome Classification :
(50 SA)
.........10........20........30.....-.-..40........50........60........70........80.....-..-.-90....-.....100.......110.......120.......130.......140.......150.......160.......170.......180.-.-..-...190.......200.......210.--..-----...-.---------220.......230.......240..-.--.-...---250........260...-....-270..-.....280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAKQ
D
I
T
V
TNYG
D
D
A
I
Q
V
L
E
G
L
D
A
V
R
KRP
G
M
Y
IGST-D-G
T
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
GFG
N
R
I
D
V
I
I
NKDG
S
I
T
V
TDHGRGMPTG-MH-A-M-GK
P
T
-
V
E
V
I
F
T
V
L
HAGGKFGQGGYKTSGGLH
G
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
IRDG
A
I
Y
R
Q
R
F
ENGGK
P
V
T
T
L
K
K
IGTAPKSKSG
T
S
V
S
FMPDQ
S
V
F
-
S
-
T
I
-
D
F
K
F
N
T
I
A
E
R
L
K
E
S
A
F
L
L
K
N
V
T
L
T
LTD--NR-----SEE-
A
---------
E
H
L
E
F
H
Y
EN
G
V
Q
D
F
V
E
Y
L
NEDKETL-
T
--
P
-
I
M
F
---F-EGEE
Q
E
F
H
I
E
V
A
L
Q
Y-NDGF-
S
D
N
I
L
-
S
F
V
N
N
VRTKDGGT
H
E
T
G
L
K
S
A
I
T
K
S
M
N
D
Y
A
R
KTGLLKEKDKNLEG
S
D
Y
R
E
G
L
S
A
I
L
S
I
LV
P
E
E
HLQFEGQ
T
K
DKLGS
P
L
A
R
P
I
V
D
G
I
V
S
E
K
L
T
Y
F
L
MENG
D
L
A
S
N
L
I
R
K
A
I
K
A
R
D
A
R
E
A
A
R
K
ARDESRNGKKSKKDKGLLSGKLTPAQSKNAKK
N
E
L
Y
L
V
EGDSAGGSAKQGRDR
K
F
Q
A
ILPLRGKVL
N
T
A
K
A
K
M
A
D
I
I
KNE
E
I
N
T
M
I
H
T
IGAGVGPDFNIDDINY
D
K
V
I
I
M
TDADTD
G
A
H
I
Q
T
L
L
L
T
F
F
Y
R
Y
M
R
P
L
V
EEG
H
V
Y
I
ALPP
L
Y
KMSKGK
G
K
K
E
I
V
E
Y
AWTDI
E
L
E
E
L
R
Q
K
FGK
G
S
L
L
Q
R
Y
KGLGEM
N
A
D
Q
L
W
E
TTMNPET
R
T
L
I
R
V
T
I
E
D
L
A
R
A
E
R
R
V
N
V
L
MGDKVP
P
R
R
Q
W
I
EDN
V
K
F
T
LEENTVF
1
PsiBlast_PDB
90.34
88%
-97
- C4 -
4JUO
4
PARE_STRPN
C:
[47-663]
-----------------------
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
D
-
G
A
G
L
H
H
L
V
W
E
I
V
D
N
A
V
D
E
A
L
S
---
D
R
I
D
V
T
I
N
K
D
G
S
L
T
V
Q
D
H
------------------
T
-
V
E
V
I
F
T
I
L
H
A
G
G
K
F
----------
L
H
G
V
G
S
S
V
V
N
A
L
S
S
W
L
E
V
E
I
T
R
D
G
A
V
Y
K
Q
R
F
E
N
G
G
K
P
V
T
T
L
K
K
I
G
T
A
P
K
S
K
T
G
T
K
V
T
F
M
P
D
A
T
I
F
-
S
-
T
T
-
D
F
K
Y
N
T
I
S
E
R
L
N
E
S
A
F
L
L
K
N
V
T
L
S
L
T
D
--
K
R
-----
T
D
E
-
A
-----------
I
E
F
H
Y
E
--
V
Q
D
F
V
S
Y
L
N
E
D
K
E
I
L
-
T
--
P
-
V
L
Y
---
F
-
E
G
E
D
N
G
F
Q
V
E
V
A
L
Q
Y
-
N
D
G
F
-
S
D
N
I
L
-
S
F
V
N
N
V
R
T
K
D
G
G
T
H
E
T
G
L
K
S
A
I
T
K
V
M
N
D
Y
A
R
K
T
G
L
L
K
E
K
----
E
G
S
D
Y
R
E
G
L
A
A
V
L
S
I
L
V
P
E
E
H
L
Q
F
E
G
Q
T
K
D
K
L
G
S
P
L
A
R
P
V
V
D
G
I
V
A
D
K
L
T
F
F
L
M
E
N
G
E
L
A
S
N
L
I
R
K
A
I
K
A
R
D
A
R
E
A
A
R
K
A
R
-------------------
L
T
P
A
Q
S
K
N
P
A
K
N
E
L
Y
L
V
E
G
D
S
A
G
G
S
A
K
Q
G
R
D
R
K
F
Q
A
I
L
P
L
R
G
K
V
I
N
T
A
K
A
K
M
A
D
I
L
K
N
E
E
I
N
T
M
I
Y
T
I
G
A
G
V
G
A
D
F
S
I
E
D
A
N
Y
D
K
I
I
I
M
T
D
A
D
T
D
G
A
H
I
Q
T
L
L
L
T
F
F
Y
R
Y
M
R
P
L
V
E
A
G
H
V
Y
I
A
-
P
P
L
Y
K
-----------
A
Y
A
W
T
D
G
E
L
E
E
L
R
K
-------
L
Q
R
Y
K
G
L
G
E
M
N
A
D
Q
L
W
E
T
T
M
N
P
E
T
R
T
L
I
R
V
T
I
E
D
L
A
R
A
E
R
R
V
N
V
L
M
G
D
K
V
E
P
R
R
K
W
I
E
D
N
V
K
F
T
-------
34
PsiBlast_CBE
61.25
45%
-79
- C3 -
3ZM7
2
GYRB_MYCTU
C:
[36-436]
--------------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
-------------------
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
----------KV-------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
--
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
--
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
60.90
45%
-80
- C3 -
3ZM7
2
GYRB_MYCTU
E:
[37-437]
---------------------
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
--------------------
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
-------------------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
---
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
--
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
60.61
45%
-72
- C3 -
1KIJ
3
?
B:
[7-372]
--------------
A
I
R
V
L
K
G
L
E
G
V
R
H
R
P
A
M
Y
I
G
G
T
-
G
-
V
E
G
Y
H
H
L
F
K
E
I
L
D
N
A
V
D
E
A
L
A
G
Y
A
T
E
I
L
V
R
L
N
E
D
G
S
L
T
V
E
D
N
G
R
G
I
P
V
D
L
M
P
-
E
-
E
-
G
K
P
A
-
V
E
V
I
Y
N
T
L
H
S
G
G
K
F
E
Q
G
A
Y
K
V
S
G
G
L
H
G
V
G
A
S
V
V
N
A
L
S
E
W
T
V
V
E
V
F
R
E
G
K
H
H
R
I
A
F
S
R
-
G
E
V
T
E
P
L
R
V
V
G
E
A
P
R
G
K
T
G
T
R
V
T
F
K
P
D
P
E
I
F
-
G
-
N
L
-
R
F
D
P
S
K
I
R
A
R
L
R
E
V
A
Y
L
V
A
G
L
K
L
V
F
Q
D
--
R
Q
-----
H
G
K
-
E
---------
E
--
V
F
L
D
K
G
G
V
A
S
F
A
K
A
L
A
E
G
E
D
L
L
-
Y
--
E
-
K
P
F
---
L
I
R
G
T
H
G
E
V
E
V
E
V
G
F
L
H
-
T
Q
G
Y
-
N
A
E
I
L
-
T
Y
A
N
M
I
P
T
R
D
G
G
T
H
L
T
A
F
K
S
A
Y
S
R
A
L
N
Q
Y
A
K
K
A
G
L
N
K
E
K
G
P
Q
P
T
G
D
D
L
L
E
G
L
Y
A
V
V
S
V
K
L
P
N
P
--
Q
F
E
G
Q
T
K
G
K
L
L
N
P
E
A
G
T
A
V
G
Q
V
V
Y
E
R
L
L
E
I
L
E
E
N
P
R
I
A
K
A
V
Y
E
K
A
L
R
A
A
Q
A
R
E
A
A
R
K
A
R
E
L
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
60.56
45%
-70
- C3 -
3ZKD
3
GYRB_MYCTU
C:
[17-426]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
VTQDE--
R
-
A
A
E
S
T
APHK
V
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
--
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
60.50
45%
-72
- C3 -
3ZKB
4
GYRB_MYCTU
B:
[17-429]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
----------V--------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
60.37
45%
-65
- C3 -
3ZKD
3
GYRB_MYCTU
H:
[17-426]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
VTQ-------K
V
-------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
---
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
60.33
45%
-71
- C3 -
3ZKB
3
GYRB_MYCTU
D:
[17-427]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
VTQ-------STAPHK
V
--
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
60.18
45%
-75
- C3 -
3ZKD
3
GYRB_MYCTU
G:
[17-425]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
V---------PHK
V
-----
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
----
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
60.10
45%
-70
- C3 -
3ZKB
3
GYRB_MYCTU
A:
[17-428]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
----------PHK
V
-----
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
---
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
59.98
45%
-71
- C3 -
3ZKD
3
GYRB_MYCTU
F:
[17-426]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
VT--------K
V
-------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
------
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
59.90
45%
-70
- C3 -
3ZKB
4
GYRB_MYCTU
C:
[17-430]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
V---------A
P
H
K
V
----
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
125
HHSearch
59.86
46%
-73
- C3 -
1KIJ
3
?
A:
[7-389]
--------------
A
I
R
V
L
K
G
L
E
G
V
R
H
R
P
A
M
Y
I
G
G
T
-
G
-
V
E
G
Y
H
H
L
F
K
E
I
L
D
N
A
V
D
E
A
L
A
G
Y
A
T
E
I
L
V
R
L
N
E
D
G
S
L
T
V
E
D
N
G
R
G
I
P
V
D
-
L
M
-
P
E
E
-
G
K
P
A
-
V
E
V
I
Y
N
T
L
H
S
G
G
K
F
E
Q
G
A
Y
K
V
S
G
G
L
H
G
V
G
A
S
V
V
N
A
L
S
E
W
T
V
V
E
V
F
R
E
G
K
H
H
R
I
A
F
S
R
G
E
V
T
E
P
-
L
R
V
V
G
E
A
P
R
G
K
T
G
T
R
V
T
F
K
P
D
P
E
I
F
-
G
-
N
L
-
R
F
D
P
S
K
I
R
A
R
L
R
E
V
A
Y
L
V
A
G
L
K
L
V
F
Q
D
--
R
Q
-----
H
G
------------
K
E
E
V
F
L
D
K
G
G
V
A
S
F
A
K
A
L
A
E
G
E
D
L
L
-
Y
--
E
K
P
F
L
---
I
-
R
G
T
H
G
E
V
E
V
E
V
G
F
L
H
-
T
Q
G
Y
-
N
A
E
I
L
-
T
Y
A
N
M
I
P
T
R
D
G
G
T
H
L
T
A
F
K
S
A
Y
S
R
A
L
N
Q
Y
A
K
K
A
G
L
N
K
E
K
G
P
Q
P
T
G
D
D
L
L
E
G
L
Y
A
V
V
S
V
K
L
P
N
P
--
Q
F
E
G
Q
T
K
G
K
L
L
N
P
E
A
G
T
A
V
G
Q
V
V
Y
E
R
L
L
E
I
L
E
E
N
P
R
I
A
K
A
V
Y
E
K
A
L
R
A
A
Q
A
R
E
A
A
R
K
A
R
E
L
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
59.72
45%
-69
- C3 -
3ZKD
3
GYRB_MYCTU
A:
[17-429]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
----------HKV------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
-----
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111
Fugue
59.63
49%
-66
- C3 -
1EI1
6
GYRB_ECOLI
A:
[1-391]
-------
S
N
S
S
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
-
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
H
-
P
E
E
-
G
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
G
-
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
-
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
------------
K
E
D
H
F
H
Y
E
G
G
I
K
A
F
V
E
Y
L
N
K
N
K
T
P
I
-
H
--
P
N
I
F
Y
---
F
-
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
-
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
--
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
59.63
45%
-66
- C3 -
3ZKD
3
GYRB_MYCTU
D:
[17-428]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
V---------K
V
-------
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
---
K
D
K
D
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
59.46
45%
-71
- C3 -
3ZKD
3
GYRB_MYCTU
E:
[17-427]
----------
Y
G
A
A
S
I
T
I
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
Y
A
T
T
V
N
V
V
L
L
E
D
G
G
V
E
V
A
D
D
G
R
G
I
P
V
A
-
T
H
-
A
-
S
-
G
I
P
T
-
V
D
V
V
M
T
Q
L
H
A
G
G
K
F
D
S
D
A
Y
A
I
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
V
E
I
K
R
D
G
Y
E
W
S
Q
V
Y
E
K
-
S
E
P
L
-
G
L
K
Q
--
G
A
P
T
K
K
T
G
S
T
V
R
F
W
A
D
P
A
V
F
-
E
-
T
T
-
E
Y
D
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
N
L
T
D
--
E
R
VTQ-------PHKV-----
K
S
R
T
F
H
Y
P
G
G
L
V
D
F
V
K
H
I
N
R
T
K
N
A
I
H
S
--
S
-
I
V
D
---
F
-
S
G
K
G
T
G
H
E
V
E
I
A
M
Q
W
-
N
A
G
Y
-
S
E
S
V
H
-
T
F
A
N
T
I
N
T
H
E
G
G
T
H
E
E
G
F
R
S
A
L
T
S
V
V
N
K
Y
A
K
D
R
K
L
L
K
D
--
P
N
L
T
G
D
D
I
R
E
G
L
A
A
V
I
S
V
K
V
S
E
P
--
Q
F
E
G
Q
T
K
T
K
L
G
N
T
E
V
K
S
F
V
Q
K
V
C
N
E
Q
L
T
H
W
F
E
A
N
P
T
D
A
K
V
V
V
N
K
A
V
S
S
A
Q
A
R
I
A
A
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
59.45
48%
-68
- C3 -
4WUB
5
GYRB_ECOLI
A:
[3-375]
---------
S
Y
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
H
-
P
-
E
E
G
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
G
-
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
E
G
G
I
K
A
F
V
E
Y
L
N
K
N
K
T
P
I
-
H
--
P
N
I
F
Y
---
F
-
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
-
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
-----
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
P
--
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
Fugue
59.40
49%
-66
- C3 -
1EI1
6
GYRB_ECOLI
A:
[1-391]
-------
S
N
S
S
D
S
S
S
I
K
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
D
D
-
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
H
-
P
E
E
-
G
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
G
-
V
P
Q
A
P
L
A
V
T
G
E
T
E
K
T
--
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
N
V
T
-
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
D
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
------------
E
D
H
F
H
Y
E
G
G
I
K
A
F
V
E
Y
L
N
K
N
K
T
P
I
-
H
--
P
N
I
F
Y
---
F
-
S
T
E
K
D
G
I
G
V
E
V
A
L
Q
W
-
N
D
G
F
-
Q
E
N
I
Y
-
C
F
T
N
N
I
P
Q
R
D
G
G
T
H
L
A
G
F
R
A
A
M
T
R
T
L
N
A
Y
M
D
K
E
G
Y
S
K
K
A
K
V
S
A
T
G
D
D
A
R
E
G
L
I
A
V
V
S
V
K
V
P
D
--
P
K
F
S
S
Q
T
K
D
K
L
V
S
S
E
V
K
S
A
V
E
Q
Q
M
N
E
L
L
A
E
Y
L
L
E
N
P
T
D
A
K
I
V
V
G
K
I
I
D
A
A
R
A
R
E
A
A
R
R
A
R
E
M
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
59.08
45%
-73
- C3 -
1KIJ
3
?
A:
[7-372]
--------------
A
I
R
V
L
K
G
L
E
G
V
R
H
R
P
A
M
Y
I
G
G
T
-
G
-
V
E
G
Y
H
H
L
F
K
E
I
L
D
N
A
V
D
E
A
L
A
G
Y
A
T
E
I
L
V
R
L
N
E
D
G
S
L
T
V
E
D
N
G
R
G
I
P
V
D
L
M
P
-
E
-
E
-
G
K
P
A
-
V
E
V
I
Y
N
T
L
H
S
G
G
K
F
E
Q
G
A
Y
K
V
S
G
G
L
H
G
V
G
A
S
V
V
N
A
L
S
E
W
T
V
V
E
V
F
R
E
G
K
H
H
R
I
A
F
S
R
-
G
E
V
T
E
P
L
R
V
V
G
E
A
P
R
G
K
T
G
T
R
V
T
F
K
P
D
P
E
I
F
-
G
-
N
L
-
R
F
D
P
S
K
I
R
A
R
L
R
E
V
A
Y
L
V
A
G
L
K
L
V
F
Q
D
--
R
Q
-----
H
G
K
-
E
---------
E
--
V
F
L
D
K
G
G
V
A
S
F
A
K
A
L
A
E
G
E
D
L
L
-
Y
--
E
-
K
P
F
---
L
I
R
G
T
H
G
E
V
E
V
E
V
G
F
L
H
-
T
Q
G
Y
-
N
A
E
I
L
-
T
Y
A
N
M
I
P
T
R
D
G
G
T
H
L
T
A
F
K
S
A
Y
S
R
A
L
N
Q
Y
A
K
K
A
G
L
N
K
E
K
G
P
Q
P
T
G
D
D
L
L
E
G
L
Y
A
V
V
S
V
K
L
P
N
P
--
Q
F
E
G
Q
T
K
G
K
L
L
N
P
E
A
G
T
A
V
G
Q
V
V
Y
E
R
L
L
E
I
L
E
E
N
P
R
I
A
K
A
V
Y
E
K
A
L
R
A
A
Q
A
R
E
A
A
R
K
A
R
E
L
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
56.61
36%
-75
- C3 -
4KQV
7
?
A:
[7-378]
-------------
K
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
---
T
-
N
-
I
E
N
P
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
-
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
N
----------
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
G
F
K
-
T
K
D
L
E
I
I
D
N
V
G
K
K
N
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
-
D
I
-
K
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
--
E
I
-----
K
K
E
-
K
-----------
L
T
W
H
F
E
T
G
L
K
G
Y
L
D
H
K
------
L
-
P
AE
P
-
F
I
I
---
D
-
N
F
S
N
G
D
S
Y
L
D
A
V
F
C
W
-
C
-----
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
-
L
S
V
K
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
--
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
R
I
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
126
HHSearch
56.58
37%
-66
- C3 -
1S16
4
PARE_ECOLI
A:
[4-383]
---------
T
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
T
D
T
T
-----
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
-
I
H
-
P
E
E
-
G
V
P
A
-
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
G
E
K
V
Q
D
-
L
Q
V
V
G
T
C
G
K
R
N
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
-
S
P
-
R
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
--
E
I
-----
N
N
------------
T
E
Q
R
W
C
Y
Q
D
G
L
N
D
Y
L
A
E
A
V
N
G
L
P
T
L
-
P
--
E
K
P
F
I
---
G
-
N
F
A
G
D
T
E
A
V
D
W
A
L
L
W
-
L
P
E
G
G
E
L
L
T
E
-
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
-
G
V
K
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
--
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
M
R
A
--
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
56.19
36%
-75
- C3 -
4HXZ
1
?
A:
[8-378]
--------------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
---
T
-
N
-
I
E
N
P
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
-
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
----------
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
G
F
K
-
T
K
D
L
E
I
I
D
N
V
G
K
K
N
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
-
D
I
-
K
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
--
E
I
-----
K
K
E
-
K
-----------
L
T
W
H
F
E
T
G
L
K
G
Y
L
D
H
K
L
E
-
A
E
T
L
-
P
AE
P
-
F
I
I
---
D
-
N
F
S
N
G
D
S
Y
L
D
A
V
F
C
W
-
C
E
D
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
-
L
S
V
K
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
--
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
R
I
N
A
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
55.80
38%
-58
- C3 -
1S16
4
PARE_ECOLI
B:
[5-383]
----------
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
---
T
-
D
-
T
T
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
E
G
V
P
A
-
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
G
E
K
-
V
Q
D
L
Q
V
V
G
T
C
G
K
R
N
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
-
S
P
-
R
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
EI
N
N
-----
T
E
Q
--------------
R
W
C
Y
Q
D
G
L
N
D
Y
L
A
E
A
V
N
G
L
P
T
L
-
P
--
E
-
K
P
F
IGN
F
-
A
G
D
T
E
A
--
V
D
W
A
L
L
W
L
P
E
G
G
-
E
L
L
T
E
-
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
G
V
K
-
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
--
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
M
R
A
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
55.44
36%
-72
- C3 -
4HYM
1
?
A:
[7-377]
-------------
K
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
---
T
-
N
-
I
E
N
P
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
-
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
N
------
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
G
F
K
-
T
K
D
L
E
I
I
D
N
V
G
K
K
N
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
-
D
I
-
K
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
--
E
I
-----
K
K
E
-
K
-----------
L
T
W
H
F
E
T
G
L
K
G
Y
L
D
H
K
L
E
-
A
E
T
L
-
P
AE
P
-
F
I
I
---
D
-
N
F
S
N
G
D
S
Y
L
D
A
V
F
C
W
-
C
E
D
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
T
P
Q
D
G
T
H
V
T
G
L
K
N
G
I
Y
D
A
I
K
A
Y
I
E
K
N
S
-----
N
I
K
I
T
A
N
D
S
F
A
Q
L
N
Y
V
I
S
V
K
I
T
N
P
--
Q
F
A
G
Q
T
K
E
K
L
S
N
K
D
V
T
N
F
V
A
T
A
V
K
D
L
L
T
I
W
L
N
Q
N
P
D
E
A
R
Q
I
V
E
N
I
S
K
V
A
Q
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
54.55
38%
-58
- C3 -
1S16
4
PARE_ECOLI
A:
[5-383]
----------
Y
N
A
D
A
I
E
V
L
T
G
L
E
P
V
R
R
R
P
G
M
Y
---
T
-
D
-
T
T
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
E
G
V
P
A
-
V
E
L
I
L
C
R
L
H
A
G
G
K
F
S
N
K
N
Y
Q
F
S
G
G
L
H
G
V
G
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
G
E
K
-
V
Q
D
L
Q
V
V
G
T
C
G
K
R
N
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
-
S
P
-
R
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
EI
N
N
-----
T
E
Q
--------------
R
W
C
Y
Q
D
G
L
N
D
Y
L
A
E
A
V
N
G
L
P
T
L
-
P
--
E
-
K
P
F
I
G
N
F
-
A
G
D
T
E
A
--
V
D
W
A
L
L
W
L
P
E
G
G
-
E
L
L
T
E
-
S
Y
V
N
L
I
P
T
M
Q
G
G
T
H
V
N
G
L
R
Q
G
L
L
D
A
M
R
E
F
C
E
Y
R
N
I
L
P
R
G
V
K
-
L
S
A
E
D
I
W
D
R
C
A
Y
V
L
S
V
K
M
Q
D
P
--
Q
F
A
G
Q
T
K
E
R
L
S
S
R
Q
C
A
A
F
V
S
G
V
V
K
D
A
F
I
L
W
L
N
Q
N
V
Q
A
A
E
L
L
A
E
M
A
I
S
S
A
Q
R
R
M
R
A
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134
HHSearch
51.01
48%
-80
* C3 *
3FV5
1
PARE_ECOLI
A:
[1-201]
--------------------
G
L
E
P
V
R
R
R
P
G
M
Y
T
D
T
T
-----
R
P
N
H
L
G
Q
E
V
I
D
N
S
V
D
E
A
L
A
G
H
A
K
R
V
D
V
I
L
H
A
D
Q
S
L
E
V
I
D
D
G
R
G
M
P
V
D
-
I
H
-
P
E
E
-
G
V
P
A
-
V
E
L
I
L
C
R
L
---------------------
I
S
V
V
N
A
L
S
K
R
V
E
V
N
V
R
R
D
G
Q
V
Y
N
I
A
F
E
N
G
E
K
V
Q
D
-
L
Q
V
V
G
T
C
G
K
R
N
T
G
T
S
V
H
F
W
P
D
E
T
F
F
-
D
-
S
P
-
R
F
S
V
S
R
L
T
H
V
L
K
A
K
A
V
L
C
P
G
V
E
I
T
F
K
D
--
E
I
-----
N
N
------------
T
E
Q
R
W
C
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
50.65
67%
-77
- C3 -
4URN
1
?
A:
[17-223]
------------------
L
E
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
D
-
K
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
-
I
H
-
K
-
S
-
G
K
P
T
-
V
E
V
I
F
T
V
L
-------------------
V
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
K
--
K
G
K
T
K
K
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
-
S
T
-
S
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
--
L
R
-----
S
G
K
-
E
---------
R
Q
E
H
Y
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
50.29
67%
-78
- C3 -
4URN
1
?
C:
[19-224]
--------------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
D
-
K
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
-
I
H
-
K
-
S
-
G
K
P
T
-
V
E
V
I
F
T
V
L
--------------------
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
K
--
K
G
K
T
K
K
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
-
S
T
-
S
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
--
L
R
-----
S
G
K
-
E
---------
R
Q
E
H
Y
H
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
PsiBlast_CBE
48.68
57%
-78
- C3 -
4URM
1
?
B:
[25-230]
---------------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
L
H
A
G
G
K
F
G
------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
PsiBlast_CBE
48.26
52%
-74
- C3 -
1AJ6
1
GYRB_ECOLI
A:
[11-216]
-----------------
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-------
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
H
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
47.41
57%
-71
- C3 -
4URO
1
GYRB_STAAU
B:
[26-230]
----------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
--------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
PsiBlast_CBE
47.32
53%
-73
- C3 -
4HYP
2
GYRB_ECOLI
C:
[2-205]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
PsiBlast_CBE
47.13
57%
-71
- C3 -
4URM
1
?
A:
[25-230]
---------------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
L
H
A
G
G
K
-------------
G
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107
PsiBlast_CBE
46.65
53%
-74
- C3 -
4HYP
2
GYRB_ECOLI
D:
[2-205]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105
PsiBlast_CBE
46.55
53%
-68
- C3 -
4KFG
3
GYRB_ECOLI
B:
[2-205]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
---------
G
V
S
A
-
A
E
V
I
M
T
V
L
-------
D
N
S
Y
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
PsiBlast_CBE
46.54
57%
-78
- C3 -
4URM
2
?
C:
[25-230]
---------------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
L
H
A
G
----------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
46.17
57%
-79
- C3 -
4URO
2
GYRB_STAAU
D:
[25-230]
---------------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
--------
P
A
-
V
E
V
I
L
T
V
--------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109
PsiBlast_CBE
45.90
53%
-71
- C3 -
4HYP
2
GYRB_ECOLI
B:
[2-205]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
45.89
52%
-70
- C3 -
4DUH
1
GYRB_ECOLI
B:
[12-217]
-----------------
V
L
K
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
H
-
P
-
E
E
G
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
------------
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
PsiBlast_CBE
45.79
53%
-72
- C3 -
4HYP
2
GYRB_ECOLI
A:
[2-205]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
-----
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
45.56
54%
-79
- C3 -
4BAE
2
GYRB_MYCSM
B:
[4-203]
--------------------
G
L
E
A
V
R
K
R
P
G
M
Y
I
G
S
T
-
G
-
E
R
G
L
H
H
L
I
W
E
V
V
D
N
A
V
D
E
A
M
A
G
F
A
T
R
V
D
V
K
I
H
A
D
G
S
V
E
V
R
D
D
G
R
G
I
P
V
E
-
M
H
-
A
-
T
-
G
M
P
T
-
I
D
V
V
M
T
Q
L
------------------
G
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
T
V
L
R
D
G
Y
E
W
F
Q
Y
Y
D
---
R
S
V
P
G
K
L
K
Q
G
G
E
T
K
-
E
T
G
T
T
I
R
F
W
A
D
P
E
I
F
-
E
-
T
T
-
D
Y
N
F
E
T
V
A
R
R
L
Q
E
M
A
F
L
N
K
G
L
T
I
E
L
T
D
--
E
R
-------
D
-
G
---------
K
H
R
V
F
H
Y
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
45.17
67%
-70
- C3 -
4URN
2
?
B:
[32-223]
---------------------------------
G
S
T
-
D
-
K
R
G
L
H
H
L
V
Y
E
I
V
D
N
S
V
D
E
V
L
N
G
Y
G
N
E
I
D
V
T
I
N
K
D
G
S
I
S
I
E
D
N
G
R
G
M
P
T
G
-
I
H
-
K
-
S
-
G
K
P
T
-
V
E
V
I
F
T
V
L
------------------
G
V
G
A
S
V
V
N
A
L
S
E
W
L
E
V
E
I
H
R
D
G
N
I
Y
H
Q
S
F
K
N
G
G
S
P
S
S
G
L
V
K
--
K
G
K
T
K
K
T
G
T
K
V
T
F
K
P
D
D
T
I
F
K
A
-
S
T
-
S
F
N
F
D
V
L
S
E
R
L
Q
E
S
A
F
L
L
K
N
L
K
I
T
L
N
D
--
L
R
-----
S
G
K
-
E
---------
R
Q
E
H
Y
H
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
45.09
36%
-81
- C3 -
4HY1
1
?
B:
[8-271]
--------------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
---
T
-
N
-
I
E
N
P
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
-
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
F
S
------------
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
G
F
K
-
T
K
D
L
E
I
I
D
N
V
G
K
K
N
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
-
D
I
-
K
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
--
E
I
-----
K
K
E
-
K
-----------
L
T
W
H
F
E
T
G
L
K
G
Y
L
D
H
K
L
--
A
E
T
L
-
P
AE-----------------------------
P
-
S
E
S
I
K
N
S
Y
V
N
L
I
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
44.95
57%
-75
- C3 -
4URO
1
GYRB_STAAU
A:
[26-230]
----------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
-------------------
G
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106
PsiBlast_CBE
44.92
53%
-66
- C3 -
4KFG
3
GYRB_ECOLI
A:
[2-206]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
-------
V
S
A
-
A
E
V
I
M
T
V
L
-----------
K
V
S
G
G
L
H
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
44.83
52%
-67
- C3 -
4DUH
1
GYRB_ECOLI
A:
[15-217]
--------------------
G
L
D
A
V
R
K
R
P
G
M
Y
I
G
D
T
-
D
D
G
T
G
L
H
H
M
V
F
E
V
V
D
N
A
I
D
E
A
L
A
G
H
C
K
E
I
I
V
T
I
H
A
D
N
S
V
S
V
Q
D
D
G
R
G
I
P
T
G
-
I
H
-
P
-
E
E
G
V
S
A
-
A
E
V
I
M
T
V
L
H
A
G
G
K
F
D
D
N
S
--------
G
V
G
V
S
V
V
N
A
L
S
Q
K
L
E
L
V
I
Q
R
E
G
K
I
H
R
Q
I
Y
E
H
-
G
V
P
Q
A
P
L
A
V
T
G
E
T
--
E
K
T
G
T
M
V
R
F
W
P
S
L
E
T
F
-
T
-
N
V
T
E
F
E
Y
E
I
L
A
K
R
L
R
E
L
S
F
L
N
S
G
V
S
I
R
L
R
D
--
K
R
-----
D
G
K
-
E
---------
D
H
--
F
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
44.63
57%
-73
- C3 -
4URM
1
?
D:
[26-230]
----------------------
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
V
L
H
A
G
----------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
43.20
57%
-69
- C3 -
4URO
1
GYRB_STAAU
C:
[25-230]
---------------------
L
E
A
A
R
K
R
P
G
M
Y
I
G
S
T
-
S
-
E
R
G
L
H
H
L
V
W
E
I
V
D
N
S
I
D
E
A
L
A
G
Y
A
N
Q
I
E
V
V
I
E
K
D
N
W
I
K
V
T
D
N
G
R
G
I
P
V
D
-
I
Q
E
K
-
M
-
G
R
P
A
-
V
E
V
I
L
T
---------------------
V
G
S
S
V
V
N
A
L
S
Q
D
L
E
V
Y
V
H
R
N
E
T
I
Y
H
Q
A
Y
K
K
G
-
V
P
Q
F
D
L
K
E
V
G
T
T
--
D
K
T
G
T
V
I
R
F
K
A
D
G
E
I
F
-
T
E
T
T
-
V
Y
N
Y
E
T
L
Q
Q
R
I
R
E
L
A
F
L
N
K
G
I
Q
I
T
L
R
D
--
E
R
-----
D
E
E
N
V
---------
R
E
D
S
Y
H
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
43.13
36%
-77
- C3 -
4KQV
2
?
B:
[8-217]
--------------
S
I
E
V
L
T
G
L
D
P
V
K
K
R
P
G
M
Y
---
T
-
N
-
I
E
N
P
N
H
L
I
Q
E
I
I
D
N
S
V
D
E
V
L
A
G
F
A
S
K
I
N
I
T
L
Y
E
D
N
S
I
E
V
A
D
D
G
R
G
M
P
V
D
-
I
H
-
P
-
E
-
H
K
M
S
G
I
E
L
I
M
T
K
L
H
S
G
G
K
--------------
V
G
V
S
V
V
N
A
L
S
T
R
L
E
A
E
I
K
R
D
G
N
V
Y
H
I
V
F
E
D
G
F
K
-
T
K
D
L
E
I
I
D
N
V
G
K
K
N
T
G
T
K
I
R
F
W
P
N
K
K
Y
F
-
D
-
D
I
-
K
V
N
F
K
A
L
K
N
L
L
E
A
K
A
I
L
C
K
A
L
T
I
K
Y
S
N
--
E
I
-----
K
K
E
-
K
-----------
L
T
W
H
F
E
T
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------