@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1256: (2015-12-06 )
MDELKKLAGVTAAKYVKNGMIVGLGTGSTAYFFVEEIGRRVKEEGLQVVGVTTSNRTTEQARGLGIPLKSADDIDVIDVTVDGADEVDPDFNGIKGGGGALLMEKIVATPTKEYIWVVDESKLVETLGAFKLPVEVVRYGSERLFRVFKSKGYCPSFRETEGDRFITDMGNYIIDLDLKKIEDPKQLANELDHTVGVVEHGLFNSMVNKVIVAGKNGLDILEK
Atome Classification :
(42 SA)
.........10..-.....----.20---.........30........-40..-..-..-..50........60........70...-.....80......-..-90..-......100.......110.......120...----...-.-130.......140..---....------.150-----.-..-------...-.160.-.---------..----.-....170......-.180.......190.......200..-..-...210.......220.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
D
E
L
K
K
L
A
G
V
T
A
A
-
K
Y
VKN----
G
M
----
I
V
G
LGTGS
T
A
Y
F
F
V
E
E
I
G
R
-
R
V
K
E-EG-
L
Q
-
V
V
G
V
TTSNR
T
T
E
Q
ARGLGIPLKSADD
I
-
D
V
I
D
V
T
VDGADEV-DP-DFNG-IKGG
G
G
A
L
L
M
E
K
I
VATPTK
E
Y
I
W
V
VD
E
S
K
L
V
E
----
T
L
G-A-FKL
P
V
E
V
V
R
Y
G
S
E
R
L
---
F
R
V
F
------KSKG-----Y-CP-------SFR-ET--E-G---------D
R
----
F
-
I
T
DMG
N
Y
I
I
D
L
D
L
-
K
KIE
D
P
K
Q
L
A
N
E
L
D
H
T
V
G
V
V
E
H
G
L
F
N
-
S
M
-
V
N
K
V
I
V
AGKNGLDILEK
59
HHSearch
95.06
77%
-96
- C10 -
3L7O
-
RPIA_STRMU
A:
[2-222]
-
E
E
L
K
K
I
A
G
V
R
A
A
-
Q
Y
V
E
D
----
G
M
----
I
V
G
L
G
T
G
S
T
A
Y
Y
F
V
E
E
V
G
R
-
R
V
Q
E
-
E
G
-
L
Q
-
V
I
G
V
T
T
S
S
R
T
T
A
Q
A
Q
A
L
G
I
P
L
K
S
I
D
E
V
-
D
S
V
D
V
T
V
D
G
A
D
E
V
-
D
P
-
N
F
N
G
-
I
K
G
G
G
G
A
L
L
M
E
K
I
V
G
T
L
T
K
D
Y
I
W
V
V
D
E
S
K
M
V
D
----
T
L
G
-
A
-
F
R
L
P
V
E
V
V
Q
Y
G
A
E
R
L
---
F
R
E
F
------
E
K
K
G
-----
Y
-
K
P
-------
S
F
R
-
E
Y
--
D
-
G
---------
V
R
----
F
-
V
T
D
M
K
N
F
I
I
D
L
D
L
-
G
S
I
P
D
P
I
A
F
G
N
M
L
D
H
Q
V
G
V
V
E
H
G
L
F
N
-
G
M
-
V
N
R
V
I
V
A
G
---
V
R
I
L
E
A
1
PsiBlast_PDB
94.79
76%
-96
- C10 -
3L7O
-
RPIA_STRMU
A:
[2-222]
-
E
E
L
K
K
I
A
G
V
R
A
A
-
Q
Y
V
E
D
----
G
M
----
I
V
G
L
G
T
G
S
T
A
Y
Y
F
V
E
E
V
G
R
-
R
V
Q
E
-
E
G
-
L
Q
-
V
I
G
V
T
T
S
S
R
T
T
A
Q
A
Q
A
L
G
I
P
L
K
S
I
D
E
V
-
D
S
V
D
V
T
V
D
G
A
D
E
V
-
D
P
-
N
F
N
G
-
I
K
G
G
G
G
A
L
L
M
E
K
I
V
G
T
L
T
K
D
Y
I
W
V
V
D
E
S
K
M
V
D
----
T
L
G
-
A
-
F
R
L
P
V
E
V
V
Q
Y
G
A
E
R
L
---
F
R
E
F
------
E
K
K
G
-----
Y
-
K
P
-------
S
F
R
-
E
Y
--
D
-
G
---------
V
R
----
F
-
V
T
D
M
K
N
F
I
I
D
L
D
L
-
G
S
I
P
D
P
I
A
F
G
N
M
L
D
H
Q
V
G
V
V
E
H
G
L
F
N
-
G
M
-
V
N
R
V
I
V
A
G
---
V
R
I
L
E
A
21
PsiBlast_CBE
92.46
58%
-95
- C10 -
4GMK
3
?
B:
[5-226]
-
D
E
L
K
Q
L
V
G
T
K
A
V
-
E
W
I
K
D
----
G
M
----
I
V
G
L
G
T
G
S
T
V
K
Y
M
V
D
A
L
G
K
-
R
V
N
E
-
E
G
-
L
D
-
I
V
G
V
T
T
S
I
R
T
A
E
Q
A
K
S
L
G
I
V
I
K
D
I
D
E
V
-
D
H
I
D
L
T
I
D
G
A
D
E
I
-
S
S
-
D
F
Q
G
-
I
K
G
G
G
A
A
L
L
Y
E
K
I
V
A
T
K
S
N
K
N
M
W
I
V
D
E
S
K
M
V
D
----
D
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
Y
G
S
G
T
V
---
F
K
R
F
------
E
E
K
G
-----
L
-
N
P
-------
E
F
R
-
K
N
--
E
D
G
---------
S
L
----
L
-
H
T
D
S
D
N
Y
I
I
D
L
H
L
-
G
K
I
E
N
P
K
E
L
G
D
Y
L
I
N
Q
V
G
V
V
E
H
G
L
F
L
-
D
I
-
V
N
T
V
I
V
G
R
Q
D
G
P
E
V
L
E
A
2
PsiBlast_PDB
91.14
58%
-94
- C10 -
4GMK
4
?
A:
[5-226]
-
D
E
L
K
Q
L
V
G
T
K
A
V
-
E
W
I
K
D
----
G
M
----
I
V
G
L
G
T
G
S
T
V
K
Y
M
V
D
A
L
G
K
-
R
V
N
E
-
E
G
-
L
D
-
I
V
G
V
T
T
S
I
R
T
A
E
Q
A
K
S
L
G
I
V
I
K
D
I
D
E
V
-
D
H
I
D
L
T
I
D
G
A
D
E
I
-
S
S
-
D
F
Q
G
-
I
K
G
G
G
A
A
L
L
Y
E
K
I
V
A
T
K
S
N
K
N
M
W
I
V
D
E
S
K
M
V
D
----
D
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
Y
G
S
G
T
V
---
F
K
R
F
------
E
E
K
G
-----
L
-
N
P
-------
E
F
R
-
K
N
--
E
D
G
---------
S
L
----
L
-
H
T
D
S
D
N
Y
I
I
D
L
H
L
-
G
K
I
E
N
P
K
E
L
G
D
Y
L
I
N
Q
V
G
V
V
E
H
G
L
F
L
-
D
I
-
V
N
T
V
I
V
G
R
Q
D
G
P
E
V
L
E
A
5
PsiBlast_PDB
81.45
43%
-92
- C10 -
1UJ5
3
RPIA_THET2
A:
[5-225]
L
E
S
Y
K
K
E
A
A
H
A
A
I
-
A
Y
V
Q
D
----
G
M
----
V
V
G
L
G
T
G
S
T
A
R
Y
A
V
L
E
L
A
R
-
R
L
R
E
-
G
E
-
L
K
G
V
V
G
V
P
T
S
R
A
T
E
E
L
A
K
R
E
G
I
P
L
V
D
L
P
P
--
E
G
V
D
L
A
I
D
G
A
D
E
I
-
A
P
-
G
L
A
L
-
I
K
G
M
G
G
A
L
L
R
E
K
I
V
E
R
V
A
K
E
F
I
V
I
A
D
H
T
K
K
V
P
----
V
L
G
-
R
-
G
P
V
P
V
E
I
V
P
F
G
Y
R
A
T
---
L
K
A
I
------
A
D
L
G
-----
G
-
E
P
-------
E
L
R
--
M
--
D
-
G
---------
D
E
----
F
Y
F
T
D
G
G
H
L
I
A
D
C
R
F
-
G
P
I
G
D
P
L
G
L
H
R
A
L
L
E
I
P
G
V
V
E
T
G
L
F
V
-
G
M
-
A
T
R
A
L
V
A
G
P
F
G
V
E
E
L
L
P
68
HHSearch
80.47
42%
-85
- C10 -
3IXQ
5
RPIA_METJA
A:
[4-226]
-
E
D
L
K
L
K
V
A
K
E
A
V
-
K
L
V
K
D
----
G
M
----
V
I
G
L
G
T
G
S
T
A
A
L
F
I
R
E
L
G
N
-
R
I
R
E
-
E
E
-
L
T
-
V
F
G
I
P
T
S
F
E
A
K
M
L
A
M
Q
Y
E
I
P
L
V
T
L
D
E
--
Y
D
V
D
I
A
F
D
G
A
D
E
V
-
E
E
T
T
L
F
L
-
I
K
G
G
G
G
C
H
T
Q
E
K
I
V
D
Y
N
A
N
E
F
V
V
L
V
D
E
S
K
L
V
K
----
K
L
G
E
K
-
F
P
I
P
V
E
V
I
P
S
A
Y
R
V
V
---
I
R
A
L
------
S
E
M
G
-----
G
-
E
A
-------
V
I
R
-
L
G
DR
K
-
R
---------
G
P
----
V
-
I
T
D
N
G
N
M
I
I
D
V
F
M
-
N
-
I
D
D
A
I
E
L
E
K
E
I
N
N
I
P
G
V
V
E
N
G
I
F
T
-
K
--
V
D
K
V
L
V
G
T
K
K
G
V
K
T
L
K
K
32
PsiBlast_CBE
80.35
42%
-90
- C10 -
3IXQ
5
RPIA_METJA
D:
[4-226]
-
E
D
L
K
L
K
V
A
K
E
A
V
-
K
L
V
K
D
----
G
M
----
V
I
G
L
G
T
G
S
T
A
A
L
F
I
R
E
L
G
N
-
R
I
R
E
-
E
E
-
L
T
-
V
F
G
I
P
T
S
F
E
A
K
M
L
A
M
Q
Y
E
I
P
L
V
T
L
D
E
Y
-
D
V
-
D
I
A
F
D
G
A
D
E
V
E
E
T
-
T
L
F
L
-
I
K
G
G
G
G
C
H
T
Q
E
K
I
V
D
Y
N
A
N
E
F
V
V
L
V
D
E
S
K
L
V
K
----
K
L
G
E
K
-
F
P
I
P
V
E
V
I
P
S
A
Y
R
V
V
---
I
R
A
L
------
S
E
M
G
-----
G
-
E
A
-------
V
I
R
-----
L
-
G
---------
D
R
KRGP
V
-
I
T
D
N
G
N
M
I
I
D
V
-
F
-
M
N
I
D
D
A
I
E
L
E
K
E
I
N
N
I
P
G
V
V
E
N
G
I
F
--
T
K
-
V
D
K
V
L
V
G
T
K
K
G
V
K
T
L
K
K
13
PsiBlast_PDB
79.69
42%
-87
- C10 -
3IXQ
5
RPIA_METJA
A:
[4-226]
-
E
D
L
K
L
K
V
A
K
E
A
V
-
K
L
V
K
D
----
G
M
----
V
I
G
L
G
T
G
S
T
A
A
L
F
I
R
E
L
G
N
-
R
I
R
E
-
E
E
-
L
T
-
V
F
G
I
P
T
S
F
E
A
K
M
L
A
M
Q
Y
E
I
P
L
V
T
L
D
E
Y
-
D
V
-
D
I
A
F
D
G
A
D
E
V
E
E
T
-
T
L
F
L
-
I
K
G
G
G
G
C
H
T
Q
E
K
I
V
D
Y
N
A
N
E
F
V
V
L
V
D
E
S
K
L
V
K
----
K
L
G
E
K
-
F
P
I
P
V
E
V
I
P
S
A
Y
R
V
V
---
I
R
A
L
------
S
E
M
G
-----
G
-
E
A
-------
V
I
R
-----
L
-
G
---------
D
R
KRGP
V
-
I
T
D
N
G
N
M
I
I
D
V
-
F
-
M
N
I
D
D
A
I
E
L
E
K
E
I
N
N
I
P
G
V
V
E
N
G
I
F
--
T
K
-
V
D
K
V
L
V
G
T
K
K
G
V
K
T
L
K
K
33
PsiBlast_CBE
79.57
42%
-89
- C10 -
3IXQ
5
RPIA_METJA
C:
[4-226]
-
E
D
L
K
L
K
V
A
K
E
A
V
-
K
L
V
K
D
----
G
M
----
V
I
G
L
G
T
G
S
T
A
A
L
F
I
R
E
L
G
N
-
R
I
R
E
-
E
E
-
L
T
-
V
F
G
I
P
T
S
F
E
A
K
M
L
A
M
Q
Y
E
I
P
L
V
T
L
D
E
Y
-
D
V
-
D
I
A
F
D
G
A
D
E
V
E
E
T
-
T
L
F
L
-
I
K
G
G
G
G
C
H
T
Q
E
K
I
V
D
Y
N
A
N
E
F
V
V
L
V
D
E
S
K
L
V
K
----
K
L
G
E
K
-
F
P
I
P
V
E
V
I
P
S
A
Y
R
V
V
---
I
R
A
L
------
S
E
M
G
-----
G
-
E
A
-------
V
I
R
-----
L
-
G
---------
D
R
KRGP
V
-
I
T
D
N
G
N
M
I
I
D
V
-
F
-
M
N
I
D
D
A
I
E
L
E
K
E
I
N
N
I
P
G
V
V
E
N
G
I
F
--
T
K
-
V
D
K
V
L
V
G
T
K
K
G
V
K
T
L
K
K
12
PsiBlast_PDB
79.57
41%
-88
- C10 -
1UJ6
3
RPIA_THET2
A:
[5-225]
L
E
S
Y
K
K
E
A
A
H
A
A
I
-
A
Y
V
Q
D
----
G
M
----
V
V
G
L
G
T
G
S
T
A
R
Y
A
V
L
E
L
A
R
-
R
L
R
E
-
G
E
-
L
K
G
V
V
G
V
P
T
S
R
A
T
E
E
L
A
K
R
E
G
I
P
L
V
D
L
P
P
--
E
G
V
D
L
A
I
D
G
A
D
E
I
-
A
P
-
G
L
A
L
-
I
K
G
M
G
G
A
L
L
R
E
K
I
V
E
R
V
A
K
E
F
I
V
I
A
D
H
T
K
K
V
P
----
V
L
G
-
R
-
G
P
V
P
V
E
I
V
P
F
G
Y
R
A
T
---
L
K
A
I
------
A
D
L
G
-----
G
-
E
P
-------
E
L
R
-
M
D
--
G
-
D
---------
E
F
----
Y
-
F
T
D
G
G
H
L
I
A
D
C
R
F
-
G
P
I
G
D
P
L
G
L
H
R
A
L
L
E
I
P
G
V
V
E
T
G
L
F
V
-
G
M
-
A
T
R
A
L
V
A
G
P
F
G
V
E
E
L
L
P
11
PsiBlast_PDB
79.55
41%
-86
- C10 -
1UJ4
3
RPIA_THET2
A:
[5-225]
L
E
S
Y
K
K
E
A
A
H
A
A
I
-
A
Y
V
Q
D
----
G
M
----
V
V
G
L
G
T
G
S
T
A
R
Y
A
V
L
E
L
A
R
-
R
L
R
E
-
G
E
-
L
K
G
V
V
G
V
P
T
S
R
A
T
E
E
L
A
K
R
E
G
I
P
L
V
D
L
P
P
--
E
G
V
D
L
A
I
D
G
A
D
E
I
-
A
P
-
G
L
A
L
-
I
K
G
M
G
G
A
L
L
R
E
K
I
V
E
R
V
A
K
E
F
I
V
I
A
D
H
T
K
K
V
P
----
V
L
G
-
R
-
G
P
V
P
V
E
I
V
P
F
G
Y
R
A
T
---
L
K
A
I
------
A
D
L
G
-----
G
-
E
P
-------
E
L
R
-
M
D
--
G
-
D
---------
E
F
----
Y
-
F
T
D
G
G
H
L
I
A
D
C
R
F
-
G
P
I
G
D
P
L
G
L
H
R
A
L
L
E
I
P
G
V
V
E
T
G
L
F
V
-
G
M
-
A
T
R
A
L
V
A
G
P
F
G
V
E
E
L
L
P
34
PsiBlast_CBE
79.21
42%
-89
- C10 -
3IXQ
5
RPIA_METJA
B:
[4-226]
-
E
D
L
K
L
K
V
A
K
E
A
V
-
K
L
V
K
D
----
G
M
----
V
I
G
L
G
T
G
S
T
A
A
L
F
I
R
E
L
G
N
-
R
I
R
E
-
E
E
-
L
T
-
V
F
G
I
P
T
S
F
E
A
K
M
L
A
M
Q
Y
E
I
P
L
V
T
L
D
E
Y
-
D
V
-
D
I
A
F
D
G
A
D
E
V
E
E
T
-
T
L
F
L
-
I
K
G
G
G
G
C
H
T
Q
E
K
I
V
D
Y
N
A
N
E
F
V
V
L
V
D
E
S
K
L
V
K
----
K
L
G
E
K
-
F
P
I
P
V
E
V
I
P
S
A
Y
R
V
V
---
I
R
A
L
------
S
E
M
G
-----
G
-
E
A
-------
V
I
R
-----
L
-
G
---------
D
R
KRGP
V
-
I
T
D
N
G
N
M
I
I
D
V
-
F
-
M
N
I
D
D
A
I
E
L
E
K
E
I
N
N
I
P
G
V
V
E
N
G
I
F
--
T
K
-
V
D
K
V
L
V
G
T
K
K
G
V
K
T
L
K
K
63
HHSearch
79.01
42%
-86
- C10 -
1UJ6
3
RPIA_THET2
A:
[6-225]
-
E
S
Y
K
K
E
A
A
H
A
A
I
-
A
Y
V
Q
D
----
G
M
----
V
V
G
L
G
T
G
S
T
A
R
Y
A
V
L
E
L
A
R
-
R
L
R
E
-
G
E
L
K
G
-
V
V
G
V
P
T
S
R
A
T
E
E
L
A
K
R
E
G
I
P
L
V
D
L
P
P
--
E
G
V
D
L
A
I
D
G
A
D
E
I
-
A
P
-
G
L
A
L
-
I
K
G
M
G
G
A
L
L
R
E
K
I
V
E
R
V
A
K
E
F
I
V
I
A
D
H
T
K
K
V
P
----
V
L
G
-
R
-
G
P
V
P
V
E
I
V
P
F
G
Y
R
A
T
---
L
K
A
I
------
A
D
L
G
-----
G
-
E
P
-------
E
L
R
-
M
D
--
G
-
D
---------
E
F
----
Y
-
F
T
D
G
G
H
L
I
A
D
C
R
F
-
G
P
I
G
D
P
L
G
L
H
R
A
L
L
E
I
P
G
V
V
E
T
G
L
F
V
-
G
M
-
A
T
R
A
L
V
A
G
P
F
G
V
E
E
L
L
P
25
PsiBlast_CBE
79.01
39%
-80
- C10 -
1LK5
5
RPIA_PYRHO
D:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
27
PsiBlast_CBE
78.25
39%
-79
- C10 -
1LK5
5
RPIA_PYRHO
B:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
18
PsiBlast_PDB
78.21
39%
-82
- C10 -
4NML
3
?
A:
[4-249]
Q
D
K
A
K
Q
A
V
G
Y
F
A
V
D
T
Y
V
R
S
----
G
M
----
K
V
G
L
G
T
G
T
T
A
K
F
V
V
E
R
I
G
Q
-
R
M
Q
E
-
G
S
-
L
K
D
L
L
C
V
P
T
S
E
A
T
R
K
Q
A
E
S
L
G
I
P
L
T
T
L
D
G
I
A
D
C
L
D
V
A
I
D
G
A
D
E
I
-
L
P
-
P
T
L
G
L
V
K
G
R
G
G
A
L
L
R
E
K
M
I
A
A
A
A
K
T
F
I
V
A
A
D
E
T
K
L
V
S
NGIG
S
T
G
-
A
---
L
P
V
E
V
V
V
F
S
G
S
H
T
---
K
R
L
L
S
A
L
P
S
V
K
R
H
G
-----
G
-
R
A
-------
E
F
R
-
K
R
--
A
-
G
AAQEDIREE
D
R
----
F
-
V
T
D
N
G
N
Y
I
V
D
L
Y
F
T
E
T
V
P
D
L
H
E
M
D
K
E
L
K
S
I
P
G
V
V
E
T
G
F
F
L
-
D
L
-
A
S
V
C
L
I
G
K
A
D
G
S
V
A
T
L
T
24
PsiBlast_CBE
78.06
39%
-79
- C10 -
1LK7
6
RPIA_PYRHO
B:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
26
PsiBlast_CBE
77.90
39%
-77
- C10 -
1LK5
5
RPIA_PYRHO
C:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
60
HHSearch
77.74
39%
-82
* C10 *
1LK5
5
RPIA_PYRHO
A:
[3-228]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
-
G
E
I
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
Q
K
-
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
---
I
E
E
L
------
S
I
F
N
-----
A
-
K
A
-------
E
L
R
-
M
G
VN
K
-
D
---------
G
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
3
PsiBlast_PDB
76.82
39%
-78
- C10 -
1LK5
5
RPIA_PYRHO
A:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
I
E
E
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
4
PsiBlast_PDB
76.81
39%
-77
- C10 -
1LK7
6
RPIA_PYRHO
A:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
I
E
E
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
22
PsiBlast_CBE
76.70
39%
-77
- C10 -
1LK7
6
RPIA_PYRHO
D:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
23
PsiBlast_CBE
76.29
39%
-77
- C10 -
1LK7
6
RPIA_PYRHO
C:
[3-229]
V
E
E
M
K
K
I
A
A
K
E
A
L
-
K
F
I
E
D
----
D
M
----
V
I
G
L
G
T
G
S
T
T
A
Y
F
I
K
L
L
G
E
-
K
L
K
R
G
E
I
-
S
D
-
I
V
G
V
P
T
S
Y
Q
A
K
L
L
A
I
E
H
D
I
P
I
A
S
L
D
Q
V
-
D
A
I
D
V
A
V
D
G
A
D
E
V
-
D
P
-
N
L
N
L
-
I
K
G
R
G
A
A
L
T
M
E
K
I
I
E
Y
R
A
G
T
F
I
V
L
V
D
E
R
K
L
V
D
----
Y
L
C
-
Q
K
M
P
V
P
I
E
V
I
P
Q
A
W
K
A
I
IEE
L
S
I
F
------
N
A
K
A
-----
E
-
L
R
-------
M
G
V
-
N
K
--
D
-
G
----------
P
----
V
-
I
T
D
N
G
N
F
I
I
D
A
K
F
-
P
R
I
D
D
P
L
D
M
E
I
E
L
N
T
I
P
G
V
I
E
N
G
I
F
A
-
D
I
-
A
D
I
V
I
V
G
T
R
E
G
V
K
K
L
E
R
65
HHSearch
74.76
38%
-78
- C10 -
3HHE
4
RPIA_BARHE
A:
[25-250]
-
Q
Q
L
K
K
M
A
A
L
K
A
L
-
E
F
V
E
D
----
D
M
----
R
L
G
I
G
S
G
S
T
V
N
E
F
I
P
L
L
G
E
-
R
V
A
N
-
G
--
L
R
-
V
T
C
V
A
T
S
Q
Y
S
E
Q
L
C
H
K
F
G
V
P
I
S
T
L
E
K
I
-
P
E
L
D
L
D
I
D
G
A
D
E
I
-
G
P
-
E
M
T
L
-
I
K
G
G
G
G
A
L
L
H
E
K
I
V
A
S
A
S
R
A
M
F
V
I
A
D
E
T
K
M
V
K
----
T
L
G
-
A
-
F
A
L
P
I
E
V
N
P
F
G
I
H
A
T
---
R
I
A
I
------
E
K
A
A
D
N
L
G
L
S
G
E
I
-------
T
L
R
-
M
N
--
G
-
D
---------
D
P
----
F
-
K
T
D
G
G
H
F
I
F
D
A
F
W
-
G
R
I
L
Q
P
K
L
L
S
E
A
L
L
A
I
P
G
V
V
E
H
G
L
F
L
-
G
L
-
A
S
R
A
I
V
A
M
A
D
S
Q
I
K
V
L
E
7
PsiBlast_PDB
73.04
39%
-76
- C10 -
3HHE
4
RPIA_BARHE
A:
[24-241]
V
Q
Q
L
K
K
M
A
A
L
K
A
L
-
E
F
V
E
D
----
D
M
----
R
L
G
I
G
S
G
S
T
V
N
E
F
I
P
L
L
G
E
-
R
V
A
N
--
G
-
L
R
-
V
T
C
V
A
T
S
Q
Y
S
E
Q
L
C
H
K
F
G
V
P
I
S
T
L
E
K
I
-
P
E
L
D
L
D
I
D
G
A
D
E
I
-
G
P
-
E
M
T
L
-
I
K
G
G
G
G
A
L
L
H
E
K
I
V
A
S
A
S
R
A
M
F
V
I
A
D
E
T
K
M
V
K
----
T
L
G
-
A
-
F
A
L
P
I
E
V
N
P
F
G
I
H
A
T
----
R
I
A
------
I
E
K
A
-----
A
-
D
N
L
G
L
S
G
E
I
T
L
R
-
M
N
--
G
-
D
---------
D
P
----
F
-
K
T
D
G
G
H
F
I
F
D
A
F
W
-
G
R
I
L
Q
P
K
L
L
S
E
A
L
L
A
I
P
G
V
V
E
H
G
L
F
L
-
G
L
-
A
S
R
A
I
V
A
M
A
D
S
Q
I
K
V
L
E
19
PsiBlast_PDB
72.36
40%
-72
- C10 -
3U7J
8
?
A:
[12-215]
-
D
E
L
K
R
L
V
G
E
A
A
A
-
R
Y
V
T
D
NVPQ
G
A
----
V
I
G
V
G
T
G
S
T
A
N
C
F
I
D
A
L
A
A
--
V
K
D
-
R
Y
-
R
G
-
A
V
--
S
S
S
V
A
T
T
E
R
L
K
S
H
G
I
R
V
F
D
L
N
E
I
-
E
S
L
Q
V
Y
V
D
G
A
D
E
I
-
D
E
-
S
G
A
M
-
I
K
G
G
G
G
A
L
T
R
E
K
I
V
A
S
V
A
E
T
F
V
C
I
A
D
A
S
K
R
V
A
----
M
L
G
-
Q
-
F
P
L
P
V
E
V
V
P
M
A
R
T
A
I
---
G
R
R
L
------
A
A
L
G
-----
G
-
V
P
-------
V
L
R
V
K
Q
--
D
-
G
---------
T
P
----
Y
-
V
T
D
N
G
N
E
I
L
D
V
K
G
-
L
R
I
D
D
P
R
A
L
E
A
A
I
N
G
W
P
G
V
V
T
V
G
L
F
A
-
Q
R
-
G
A
D
L
C
L
L
G
T
E
H
G
V
E
T
L
R
29
PsiBlast_CBE
71.31
39%
-80
- C10 -
3HHE
3
RPIA_BARHE
B:
[24-241]
V
Q
Q
L
K
K
M
A
A
L
K
A
L
-
E
F
V
E
D
----
D
M
----
R
L
G
I
G
S
G
S
T
V
N
E
F
I
P
L
L
G
E
-
R
V
A
N
--
G
-
L
R
-
V
T
C
V
A
T
S
Q
Y
S
E
Q
L
C
H
K
F
G
V
P
I
S
T
L
E
K
I
-
P
E
L
D
L
D
I
D
G
A
D
E
I
-
G
P
-
E
M
T
L
-
I
K
G
G
G
G
A
L
L
H
E
K
I
V
A
S
A
S
R
A
M
F
V
I
A
D
E
T
K
M
V
K
----
T
L
G
-
A
-
F
A
L
P
I
E
V
N
P
F
G
I
H
A
T
----
R
I
A
------
I
E
K
A
-----
A
-
D
N
LGLSGEI
T
L
R
-
M
N
--
G
-
D
---------
D
P
----
F
-
K
T
D
G
G
H
F
I
F
D
A
F
W
-
G
R
I
L
Q
P
K
L
L
S
E
A
L
L
A
I
P
G
V
V
E
H
G
L
F
L
-
G
L
-
A
S
R
A
I
V
A
M
A
D
S
Q
I
K
V
L
E
67
HHSearch
71.24
40%
-77
- C10 -
1M0S
1
RPIA_HAEIN
A:
[4-218]
-
L
E
M
K
K
L
A
A
Q
A
A
L
-
Q
Y
V
K
A
----
D
R
----
I
V
G
V
G
S
G
S
T
V
N
C
F
I
E
A
L
G
T
-
I
K
D
-----
K
I
-
Q
G
A
V
A
A
S
K
E
S
E
E
L
L
R
K
Q
G
I
E
V
F
N
A
N
D
V
-
S
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
P
-
Q
K
M
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
L
A
K
K
F
I
C
I
V
D
S
S
K
Q
V
D
----
V
L
G
S
T
-
F
P
L
P
V
E
V
I
P
M
A
R
S
Q
V
---
G
R
K
L
------
A
A
L
G
-----
G
-
S
P
-------
E
Y
R
-
E
----------------
G
----
V
-
V
T
D
N
G
N
V
I
L
D
V
H
N
-
F
S
I
L
N
P
V
E
I
E
K
E
L
N
N
V
A
G
V
V
T
N
G
I
F
A
L
R
G
-
A
D
V
V
I
V
G
T
P
E
G
A
K
V
I
D
-
10
PsiBlast_PDB
70.08
41%
-67
- C10 -
3ENW
1
RPIA_VIBVY
A:
[21-226]
-
D
E
M
K
K
A
A
G
W
A
A
L
-
K
Y
V
E
K
----
G
S
----
I
V
G
V
G
T
G
S
T
V
N
H
F
I
D
A
L
G
T
-
M
S
E
E
I
K
G
------
A
V
S
S
S
V
A
S
T
E
K
L
E
A
L
G
I
K
I
F
D
C
N
E
V
-
A
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
A
-
D
R
E
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
I
A
D
K
F
I
C
I
V
D
G
T
K
A
V
D
----
V
L
G
-
T
-
F
P
L
P
V
E
V
I
P
M
A
R
S
Y
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
C
Y
R
-
E
G
--------------------
V
-
I
T
D
N
G
N
V
I
L
D
V
Y
G
-
M
K
I
T
N
P
K
Q
L
E
D
Q
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
H
R
-
G
A
D
V
V
I
T
G
T
P
E
G
A
K
I
E
E
9
PsiBlast_PDB
70.07
41%
-62
- C10 -
3ENV
1
RPIA_VIBVY
A:
[21-226]
-
D
E
M
K
K
A
A
G
W
A
A
L
-
K
Y
V
E
K
----
G
S
----
I
V
G
V
G
T
G
S
T
V
N
H
F
I
D
A
L
G
T
-
M
S
E
E
I
K
G
------
A
V
S
S
S
V
A
S
T
E
K
L
E
A
L
G
I
K
I
F
D
C
N
E
V
-
A
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
A
-
D
R
E
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
I
A
D
K
F
I
C
I
V
D
G
T
K
A
V
D
----
V
L
G
-
T
-
F
P
L
P
V
E
V
I
P
M
A
R
S
Y
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
C
Y
R
-
E
G
--------------------
V
-
I
T
D
N
G
N
V
I
L
D
V
Y
G
-
M
K
I
T
N
P
K
Q
L
E
D
Q
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
H
R
-
G
A
D
V
V
I
T
G
T
P
E
G
A
K
I
E
E
30
PsiBlast_CBE
69.94
41%
-65
- C10 -
3ENW
1
RPIA_VIBVY
B:
[21-226]
-
D
E
M
K
K
A
A
G
W
A
A
L
-
K
Y
V
E
K
----
G
S
----
I
V
G
V
G
T
G
S
T
V
N
H
F
I
D
A
L
G
T
-
M
S
E
E
I
K
G
------
A
V
S
S
S
V
A
S
T
E
K
L
E
A
L
G
I
K
I
F
D
C
N
E
V
-
A
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
A
-
D
R
E
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
I
A
D
K
F
I
C
I
V
D
G
T
K
A
V
D
----
V
L
G
-
T
-
F
P
L
P
V
E
V
I
P
M
A
R
S
Y
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
C
Y
R
-
E
G
--------------------
V
-
I
T
D
N
G
N
V
I
L
D
V
Y
G
-
M
K
I
T
N
P
K
Q
L
E
D
Q
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
H
R
-
G
A
D
V
V
I
T
G
T
P
E
G
A
K
I
E
E
31
PsiBlast_CBE
69.40
41%
-69
- C10 -
3ENV
1
RPIA_VIBVY
B:
[21-226]
-
D
E
M
K
K
A
A
G
W
A
A
L
-
K
Y
V
E
K
----
G
S
----
I
V
G
V
G
T
G
S
T
V
N
H
F
I
D
A
L
G
T
-
M
S
E
E
I
K
G
------
A
V
S
S
S
V
A
S
T
E
K
L
E
A
L
G
I
K
I
F
D
C
N
E
V
-
A
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
A
-
D
R
E
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
I
A
D
K
F
I
C
I
V
D
G
T
K
A
V
D
----
V
L
G
-
T
-
F
P
L
P
V
E
V
I
P
M
A
R
S
Y
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
C
Y
R
-
E
G
--------------------
V
-
I
T
D
N
G
N
V
I
L
D
V
Y
G
-
M
K
I
T
N
P
K
Q
L
E
D
Q
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
H
R
-
G
A
D
V
V
I
T
G
T
P
E
G
A
K
I
E
E
46
PsiBlast_CBE
69.30
36%
-67
- C10 -
4X84
1
RPIA_PSEAE
C:
[12-221]
-
D
Q
L
K
Q
A
V
A
Q
A
A
V
-
D
H
I
L
P
----
H
L
DSK
S
I
V
G
V
G
T
G
S
T
A
N
F
F
I
D
A
L
A
R
-
H
K
A
E
F
D
G
------
A
V
A
S
S
E
A
T
A
K
R
L
K
E
H
G
I
P
V
Y
E
L
N
T
V
-
S
E
L
E
F
Y
V
D
G
A
D
E
S
-
N
E
-
R
L
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
V
A
K
T
F
I
C
I
A
D
A
S
K
L
V
P
----
I
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
M
A
R
S
H
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
V
Y
R
-
E
G
--------------------
V
-
L
T
D
N
G
N
I
I
L
D
V
H
N
-
L
R
I
D
S
P
V
E
L
E
E
K
I
N
A
I
V
G
V
V
T
N
G
L
F
A
-
A
R
-
P
A
D
L
L
L
L
G
T
A
D
G
V
K
T
L
K
39
PsiBlast_CBE
68.36
39%
-74
- C10 -
4M8L
16
RPIA_FRATW
A:
[10-204]
-
D
E
L
K
K
L
A
A
T
E
A
A
-
K
S
I
T
T
----
E
I
----
T
L
G
V
G
T
G
S
T
V
G
F
L
I
E
E
L
V
N
-
Y
--
R
-
D
K
-
I
K
-
T
V
-
V
S
S
S
E
D
S
T
R
K
L
K
A
L
G
F
D
V
V
D
L
N
Y
A
-
G
E
I
D
L
Y
I
D
G
A
D
E
C
-
N
N
-
H
K
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
C
V
A
A
A
K
K
F
I
C
I
I
D
E
S
K
K
V
N
----
T
L
G
-
N
-
F
P
L
P
I
E
V
I
P
M
A
R
S
Y
I
---
A
R
Q
I
------
V
K
L
G
-----
G
-
Q
P
-------
V
Y
R
-
E
----------------
Q
----
T
-
I
T
D
N
G
N
V
I
L
D
V
Y
N
-
L
K
I
D
N
P
L
K
L
E
T
E
L
N
Q
I
T
G
V
V
T
N
G
I
F
A
-
L
K
-
P
A
D
T
V
I
M
A
T
K
D
S
N
I
V
V
L
47
PsiBlast_CBE
68.31
36%
-65
- C10 -
4X84
1
RPIA_PSEAE
B:
[12-221]
-
D
Q
L
K
Q
A
V
A
Q
A
A
V
-
D
H
I
L
P
----
H
L
DSK
S
I
V
G
V
G
T
G
S
T
A
N
F
F
I
D
A
L
A
R
-
H
K
A
E
F
D
G
------
A
V
A
S
S
E
A
T
A
K
R
L
K
E
H
G
I
P
V
Y
E
L
N
T
V
-
S
E
L
E
F
Y
V
D
G
A
D
E
S
-
N
E
-
R
L
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
V
A
K
T
F
I
C
I
A
D
A
S
K
L
V
P
----
I
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
M
A
R
S
H
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
V
Y
R
-
E
G
--------------------
V
-
L
T
D
N
G
N
I
I
L
D
V
H
N
-
L
R
I
D
S
P
V
E
L
E
E
K
I
N
A
I
V
G
V
V
T
N
G
L
F
A
-
A
R
-
P
A
D
L
L
L
L
G
T
A
D
G
V
K
T
L
K
38
PsiBlast_CBE
67.96
39%
-74
- C10 -
4M8L
4
RPIA_FRATW
B:
[10-204]
-
D
E
L
K
K
L
A
A
T
E
A
A
-
K
S
I
T
T
----
E
I
----
T
L
G
V
G
T
G
S
T
V
G
F
L
I
E
E
L
V
N
-
Y
--
R
-
D
K
-
I
K
-
T
V
-
V
S
S
S
E
D
S
T
R
K
L
K
A
L
G
F
D
V
V
D
L
N
Y
A
-
G
E
I
D
L
Y
I
D
G
A
D
E
C
-
N
N
-
H
K
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
C
V
A
A
A
K
K
F
I
C
I
I
D
E
S
K
K
V
N
----
T
L
G
-
N
-
F
P
L
P
I
E
V
I
P
M
A
R
S
Y
I
---
A
R
Q
I
------
V
K
L
G
-----
G
-
Q
P
-------
V
Y
R
-
E
----------------
Q
----
T
-
I
T
D
N
G
N
V
I
L
D
V
Y
N
-
L
K
I
D
N
P
L
K
L
E
T
E
L
N
Q
I
T
G
V
V
T
N
G
I
F
A
-
L
K
-
P
A
D
T
V
I
M
A
T
K
D
S
N
I
V
V
L
35
PsiBlast_CBE
67.82
41%
-60
- C10 -
1M0S
1
RPIA_HAEIN
B:
[5-199]
--
E
M
K
K
L
A
A
Q
A
A
L
-
Q
Y
V
K
A
----
D
R
----
I
V
G
V
G
S
G
S
T
V
N
C
F
I
E
A
L
G
T
I
K
D
K
I
-
Q
G
------
A
V
A
A
S
K
E
S
E
E
L
L
R
K
Q
G
I
E
V
F
N
A
N
D
V
-
S
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
P
-
Q
K
M
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
L
A
K
K
F
I
C
I
V
D
S
S
K
Q
V
D
----
V
L
G
-
S
T
F
P
L
P
V
E
V
I
P
M
A
R
S
Q
V
---
G
R
K
L
------
A
A
L
G
-----
G
-
S
P
-------
E
Y
R
-
E
G
--------------------
V
-
V
T
D
N
G
N
V
I
L
D
V
H
N
-
F
S
I
L
N
P
V
E
I
E
K
E
L
N
N
V
A
G
V
V
T
N
G
I
F
A
-
L
R
-
G
A
D
V
V
I
V
G
T
P
E
G
A
K
V
I
D
48
PsiBlast_CBE
66.87
36%
-68
- C10 -
4X84
1
RPIA_PSEAE
A:
[12-221]
-
D
Q
L
K
Q
A
V
A
Q
A
A
V
-
D
H
I
L
P
----
H
L
DSK
S
I
V
G
V
G
T
G
S
T
A
N
F
F
I
D
A
L
A
R
-
H
K
A
E
F
D
G
------
A
V
A
S
S
E
A
T
A
K
R
L
K
E
H
G
I
P
V
Y
E
L
N
T
V
-
S
E
L
E
F
Y
V
D
G
A
D
E
S
-
N
E
-
R
L
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
V
A
K
T
F
I
C
I
A
D
A
S
K
L
V
P
----
I
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
M
A
R
S
H
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
V
Y
R
-
E
G
--------------------
V
-
L
T
D
N
G
N
I
I
L
D
V
H
N
-
L
R
I
D
S
P
V
E
L
E
E
K
I
N
A
I
V
G
V
V
T
N
G
L
F
A
-
A
R
-
P
A
D
L
L
L
L
G
T
A
D
G
V
K
T
L
K
45
PsiBlast_CBE
66.23
36%
-64
- C10 -
4X84
1
RPIA_PSEAE
D:
[12-221]
-
D
Q
L
K
Q
A
V
A
Q
A
A
V
-
D
H
I
L
P
----
H
L
DSKS
I
V
G
V
G
T
G
S
T
A
N
F
F
I
D
A
L
A
R
-
H
K
A
E
F
D
G
------
A
V
A
S
S
E
A
T
A
K
R
L
K
E
H
G
I
P
V
Y
E
L
N
T
V
-
S
E
L
E
F
Y
V
D
G
A
D
E
S
-
N
E
-
R
L
E
L
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
V
A
K
T
F
I
C
I
A
D
A
S
K
L
V
P
----
I
L
G
-
Q
-
F
P
L
P
V
E
V
I
P
M
A
R
S
H
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
D
P
-------
V
Y
R
-
E
G
--------------------
V
-
L
T
D
N
G
N
I
I
L
D
V
H
N
-
L
R
I
D
S
P
V
E
L
E
E
K
I
N
A
I
V
G
V
V
T
N
G
L
F
A
-
A
R
-
P
A
D
L
L
L
L
G
T
A
D
G
V
K
T
L
K
14
PsiBlast_PDB
64.83
41%
-58
- C10 -
1M0S
1
RPIA_HAEIN
A:
[5-199]
--
E
M
K
K
L
A
A
Q
A
A
L
-
Q
Y
V
K
A
----
D
R
----
I
V
G
V
G
S
G
S
T
V
N
C
F
I
E
A
L
G
T
I
K
D
K
I
-
Q
G
------
A
V
A
A
S
K
E
S
E
E
L
L
R
K
Q
G
I
E
V
F
N
A
N
D
V
-
S
S
L
D
I
Y
V
D
G
A
D
E
I
-
N
P
-
Q
K
M
M
-
I
K
G
G
G
A
A
L
T
R
E
K
I
V
A
A
L
A
K
K
F
I
C
I
V
D
S
S
K
Q
V
D
----
V
L
G
-
S
T
F
P
L
P
V
E
V
I
P
M
A
R
S
Q
V
---
G
R
K
L
------
A
A
L
G
-----
G
-
S
P
-------
E
Y
R
-
E
G
--------------------
V
-
V
T
D
N
G
N
V
I
L
D
V
H
N
-
F
S
I
L
N
P
V
E
I
E
K
E
L
N
N
V
A
G
V
V
T
N
G
I
F
A
-
L
R
-
G
A
D
V
V
I
V
G
T
P
E
G
A
K
V
I
D
64
HHSearch
60.55
38%
-65
- C10 -
1O8B
1
RPIA_ECOLI
A:
[23-218]
-----------------------------
I
V
G
V
G
T
G
S
T
----------------------
E
G
A
V
S
S
S
D
A
------------
F
D
L
N
E
V
-
D
S
L
G
I
Y
V
D
G
A
D
E
I
-
N
G
-
H
M
Q
M
-
I
K
G
G
G
-
A
L
T
R
E
K
I
I
A
S
V
A
E
K
F
I
C
I
A
D
A
S
K
Q
V
D
----
I
L
G
-
K
-
F
P
L
P
V
E
V
I
P
M
A
R
S
A
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
R
P
-------
E
Y
R
-
Q
----------------
G
----
V
-
V
T
D
N
G
N
V
I
L
D
V
H
G
-
M
E
I
L
D
P
I
A
M
E
N
A
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
N
R
G
A
D
V
A
L
I
G
T
P
D
G
V
K
T
I
V
-
16
PsiBlast_PDB
55.94
39%
-56
- C10 -
1O8B
1
RPIA_ECOLI
A:
[23-198]
-----------------------------
I
V
G
V
G
T
G
S
T
----------------
E
G
------
A
V
S
S
S
D
A
------------
F
D
L
N
E
V
-
D
S
L
G
I
Y
V
D
G
A
D
E
I
-
N
G
-
H
M
Q
M
-
I
K
G
G
G
-
A
L
T
R
E
K
I
I
A
S
V
A
E
K
F
I
C
I
A
D
A
S
K
Q
V
D
----
I
L
G
-
K
-
F
P
L
P
V
E
V
I
P
M
A
R
S
A
V
---
A
R
Q
L
------
V
K
L
G
-----
G
-
R
P
-------
E
Y
R
-
Q
G
--------------------
V
-
V
T
D
N
G
N
V
I
L
D
V
H
G
-
M
E
I
L
D
P
I
A
M
E
N
A
I
N
A
I
P
G
V
V
T
V
G
L
F
A
-
N
R
-
G
A
D
V
A
L
I
G
T
P
D
G
V
K
T
I
V