@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1383: (2015-12-07 )
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDRAKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKNILFIVGGAFDGIEDLVKQRLGEKIIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRILTEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGTDKPVLETA
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260-.......270..--.....---280.......290.......300.......310.......320.......330.......340.......350......-----.360.......370.......380.......390.......400......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAGNRNND
M
N
V
Y
C
SFCGK
S
Q
D
E
V
K
K
I
IAGN
G
V
F
I
C
N
E
C
V
A
L
S
Q
E
I
I
K
E
E
L
A
E
E
V
L
A
D
L
A
EVP
K
P
K
E
L
L
E
I
L
N
Q
Y
VV
G
Q
D
R
A
K
R
A
L
A
V
A
V
Y
N
HYKRVSYTESSDDDVDLQKS
N
I
L
M
I
GPTGS
G
K
T
F
L
A
Q
T
L
A
K
SLNV
P
F
A
IADATSLTEAGYV
G
E
D
V
E
N
I
L
L
K
L
I
Q
AADY
N
V
E
R
AER
G
I
I
Y
V
D
E
I
D
K
I
A
KKGE
N
V
S
I
T
RDVS
G
E
G
V
Q
Q
A
L
L
K
I
I
E
G
T
V
ASVPPQGGRKHPNQ
E
M
I
Q
I
NT
K
N
I
L
F
I
VGG
A
F
D
G
I
E
D
L
V
K
Q
R
L
G
E
-
K
I
IGFGQTSRKI--DD
N
A
S
---
Y
M
Q
E
I
I
S
E
D
I
Q
KFG
L
I
P
E
F
I
GR
L
P
V
V
A
A
L
E
L
L
T
A
E
D
L
V
R
I
L
TE
P
R
N
A
L
V
K
Q
Y
Q
T
L
L
SYDG
V
E
L
E
FDQ
D
A
L
L
A
I
A
D
K
A
I
E
-----
R
K
T
G
A
R
G
L
R
S
I
I
E
E
T
M
L
D
I
M
FEIPSQED
V
T
K
V
R
I
T
K
A
AVEGTDKPVLETA
6
PsiBlast_PDB
97.76
60%
-128
- C6 -
4I81
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
-----
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
S
----------
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
---------------------E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
34
PsiBlast_CBE
96.75
60%
-125
- C6 -
4I4L
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
----
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
---
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
--------
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
38
PsiBlast_CBE
96.68
60%
-128
- C6 -
4I81
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
G
-
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
-----
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
-------------
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
21
PsiBlast_CBE
96.27
60%
-127
- C6 -
4I9K
2
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
--------
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
---------
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
---------------------EGE
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
31
PsiBlast_CBE
96.04
60%
-127
- C6 -
4I4L
2
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
--------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
-
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
-------------
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
---------------------E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
27
PsiBlast_CBE
95.92
60%
-124
- C6 -
4I5O
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
-------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
---------
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
4
PsiBlast_PDB
95.86
60%
-127
- C6 -
4I9K
3
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
--------
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
---------
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
---------------------E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
42
PsiBlast_CBE
95.66
60%
-118
- C6 -
3HWS
4
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
G
-
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
-------------
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
---------
R
K
H
P
Q
Q
E
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
G
136
HHSearch
95.33
60%
-116
- C6 -
3HWS
4
CLPX_ECOLI
A:
[3-351]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
G
S
-----------DK
A
S
E
G
E
---
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
2
PsiBlast_PDB
95.23
60%
-124
- C6 -
4I5O
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
----
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
---
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
---------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
30
PsiBlast_CBE
94.97
60%
-125
- C6 -
4I4L
1
CLPX_ECOLI
F:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
---
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
----
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
----------
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
29
PsiBlast_CBE
94.75
60%
-122
- C6 -
4I5O
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
--------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
---------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
41
PsiBlast_CBE
94.51
60%
-123
- C6 -
3HWS
3
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
G
-
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
----------
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
V
A
A
V
P
-------------
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
G
23
PsiBlast_CBE
94.49
60%
-121
- C6 -
4I63
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
----
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
---
22
PsiBlast_CBE
94.45
60%
-119
- C6 -
4I63
1
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
----
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
-------------
D
K
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
5
PsiBlast_PDB
94.36
60%
-118
- C6 -
3HWS
4
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
G
-
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
-------------
D
K
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
1
PsiBlast_PDB
94.34
60%
-120
- C6 -
4I34
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
N
G
-
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
24
PsiBlast_CBE
94.33
60%
-123
- C6 -
4I63
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-----
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
-------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
32
PsiBlast_CBE
94.11
60%
-121
- C6 -
4I4L
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
---
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
3
PsiBlast_PDB
94.06
60%
-123
- C6 -
4I63
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-----
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
-
137
HHSearch
66.02
41%
-102
- C6 -
1G41
2
HSLU_HAEIN
A:
[249-434]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
N
G
I
V
F
I
D
E
I
D
K
I
C
K
K
G
E
Y
S
--
G
A
D
V
S
R
E
G
V
Q
R
D
L
L
P
L
V
E
G
S
T
V
S
T
-----------
K
H
G
M
V
K
T
D
H
I
L
F
I
A
S
G
A
F
Q
V
-------------------------------------------
A
R
P
S
D
L
I
P
E
L
Q
G
R
L
P
I
R
V
E
L
T
A
L
S
A
A
D
F
E
R
I
L
T
E
P
H
A
S
L
T
E
Q
Y
K
A
L
M
A
T
E
G
V
N
I
A
F
T
T
D
A
V
K
K
I
A
E
A
A
F
R
V
N
E
K
T
E
N
I
G
A
R
R
L
H
T
V
M
E
R
L
M
D
K
I
S
F
S
A
S
D
M
N
-
G
Q
T
V
N
I
D
A
A
Y
V
A
D
A
L
G
E
V
V
E
N
E