@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1449: (2015-12-08 )
MKIVVPVMPRSLEEAQEIDLSKFDSVDIIEWRADALPKDDIINVAPAIFEKFAGHEIIFTLRTTREGGNIVLSDAEYVELIQKINSIYNPDYIDFEYFSHKEVFQEMLEFPNLVLSYHNFQETPENIMEIFSELTALAPRVVKIAVMPKNEQDVLDVMNYTRGFKTINPDQVYATVSMSKIGRISRFAGDVTGSSWTFAYLDSSIAPGQITISEMKRVKALLDAD
Atome Classification :
(26 SA)
---------------.........10----......-..20....-.-...30.....----.----.----.40...-.....50.......--..60........70........80..-.-.....90........100.......110-----.......120..--.....130.......140.......150.......160.......170.......180.......190.......200.......210.......220...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------
M
K
I
VVPVMPR
S
----
L
E
E
A
Q
E-IDLSKFDS-
V
-
D
I
I
E
W
RADAL----P----K----DDI
I
N
V
-
A
P
A
I
F
E
-
K
FAG
H
E
I
--
I
F
T
L
R
TTREGG
N
I
V
LS
D
A
E
Y
V
E
L
I
Q
K
-
I
-
N
S
IYNPDYI
D
F
E
YF
S
H
K
E
V
F
Q
E
M
L
EF
P
N
-----
L
V
L
S
YH
N
F
QET
P
--
E
N
I
M
E
I
F
S
E
L
T
A
LAP
R
V
V
K
I
A
V
MPK
N
E
Q
D
V
L
D
V
M
N
Y
TRGFKTI
N
P
D
Q
V
Y
A
T
V
S
M
S
K
I
G
R
I
S
R
F
AGDVTGS
S
W
T
F
A
Y
LDSSIAPG
Q
I
T
I
S
E
M
K
R
V
K
A
L
LDAD
1
PsiBlast_PDB
97.39
69%
-125
- C4 -
3L9C
-
AROD_STRMU
A:
[1-225]
---------------
M
K
I
V
V
P
V
M
P
Q
N
----
I
E
E
A
N
Q
-
L
D
L
T
R
I
D
S
-
T
-
D
I
I
E
W
R
A
D
Y
L
----
V
----
K
----
D
D
I
L
T
V
-
A
P
A
I
F
E
-
K
F
S
G
H
E
V
--
I
F
T
L
R
T
E
K
E
G
G
N
I
S
L
S
N
E
D
Y
L
A
I
I
R
D
-
I
-
A
A
L
Y
Q
P
D
Y
I
D
F
E
Y
F
S
Y
R
D
V
L
E
E
M
Y
D
F
S
N
-----
L
I
L
S
Y
H
N
F
E
E
T
P
--
E
N
L
M
E
V
F
S
E
L
T
A
L
A
P
R
V
V
K
I
A
V
M
P
K
N
E
Q
D
V
L
D
L
M
N
Y
T
R
G
F
K
T
L
N
P
N
Q
E
Y
V
T
M
S
M
S
K
L
G
R
I
S
R
L
A
A
D
L
I
G
S
S
W
T
F
A
S
L
-------
Q
I
S
L
A
D
M
R
K
I
K
E
V
L
D
A
N
33
HHSearch
97.24
69%
-124
- C4 -
3L9C
-
AROD_STRMU
A:
[1-225]
---------------
M
K
I
V
V
P
V
M
P
Q
N
----
I
E
E
A
N
Q
-
L
D
L
T
R
I
D
S
-
T
-
D
I
I
E
W
R
A
D
Y
L
----
V
----
K
----
D
D
I
L
T
V
-
A
P
A
I
F
E
-
K
F
S
G
H
E
V
--
I
F
T
L
R
T
E
K
E
G
G
N
I
S
L
S
N
E
D
Y
L
A
I
I
R
D
I
A
-
A
L
Y
-
Q
P
D
Y
I
D
F
E
Y
F
S
Y
R
D
V
L
E
E
M
Y
D
F
S
N
-----
L
I
L
S
Y
H
N
F
E
E
T
P
--
E
N
L
M
E
V
F
S
E
L
T
A
L
A
P
R
V
V
K
I
A
V
M
P
K
N
E
Q
D
V
L
D
L
M
N
Y
T
R
G
F
K
T
L
N
P
N
Q
E
Y
V
T
M
S
M
S
K
L
G
R
I
S
R
L
A
A
D
L
I
G
S
S
W
T
F
A
S
L
-------
Q
I
S
L
A
D
M
R
K
I
K
E
V
L
D
A
N
2
PsiBlast_PDB
96.50
67%
-118
- C4 -
2OCZ
5
AROD_STRP1
A:
[5-226]
----------------
R
I
V
A
P
V
M
P
R
H
----
F
D
E
A
Q
A
-
I
D
I
S
K
Y
E
D
-
V
-
N
L
I
E
W
R
A
D
F
L
----
P
----
K
----
D
E
I
V
A
V
-
A
P
A
I
F
E
-
K
F
A
G
K
E
I
--
I
F
T
L
R
T
V
Q
E
G
G
N
I
T
L
S
S
Q
E
Y
V
D
I
I
K
E
-
I
-
N
A
I
Y
N
P
D
Y
I
D
F
E
Y
F
T
H
K
S
V
F
Q
E
M
L
D
F
P
N
-----
L
I
L
S
Y
H
N
F
E
E
T
P
--
E
N
L
M
E
A
F
S
E
M
T
K
L
A
P
R
V
V
K
I
A
V
M
P
Q
S
E
Q
D
V
L
D
L
M
N
Y
T
R
G
F
K
T
L
N
P
E
Q
E
F
A
T
I
S
M
G
K
L
G
R
L
S
R
F
A
G
D
V
I
G
S
S
W
T
Y
V
S
L
------
G
Q
V
T
L
N
D
M
K
R
I
I
E
V
L
E
--
32
HHSearch
93.77
67%
-113
- C4 -
2OCZ
5
AROD_STRP1
A:
[4-226]
---------------
M
R
I
V
A
P
V
M
P
R
H
----
F
D
E
A
Q
A
I
D
I
-
S
K
Y
E
D
-
V
-
N
L
I
E
W
R
A
D
F
L
----
P
----
K
----
D
E
I
V
A
V
A
P
A
I
F
E
K
--
F
A
G
K
E
I
--
I
F
T
L
R
T
V
Q
E
G
G
N
I
T
L
S
S
Q
E
Y
V
D
I
I
K
E
-
I
N
A
I
Y
-
N
P
D
Y
I
D
F
E
Y
F
T
H
K
S
V
F
Q
E
M
L
D
F
P
N
-----
L
I
L
S
Y
H
N
F
E
E
T
P
--
E
N
L
M
E
A
F
S
E
M
T
K
L
A
P
R
V
V
K
I
A
V
M
P
Q
S
E
Q
D
V
L
D
L
M
N
Y
T
R
G
F
K
T
L
N
P
E
Q
E
F
A
T
I
S
M
G
K
L
G
R
L
S
R
F
A
G
D
V
I
G
S
S
W
T
Y
V
S
L
------
G
Q
V
T
L
N
D
M
K
R
I
I
E
V
L
E
--
53
Fugue
77.06
30%
-101
- C4 -
1QFE
1
AROD_SALTI
A:
[1-252]
M
K
T
V
T
V
KNLIIGEGM
P
K
I
I
V
S
L
M
G
R
D
----
I
N
S
V
K
A
-
E
A
L
A
Y
R
E
A
T
F
-
D
I
L
E
W
R
V
D
H
F
----
M
DIAS
T
----
Q
S
V
L
T
A
-
A
R
V
I
R
D
-
A
M
P
D
I
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
-
A
-
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
NVY
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
20
PsiBlast_PDB
75.47
29%
-99
- C4 -
1L9W
1
AROD_SALTI
A:
[17-249]
----------------
K
I
I
V
S
L
M
G
R
D
----
I
N
S
V
K
A
-
E
A
L
A
Y
R
E
A
-
T
F
D
I
L
E
W
R
V
D
H
F
MDIA
S
----
T
----
Q
S
V
L
T
A
-
A
R
V
I
R
D
-
A
M
P
D
I
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
-
A
-
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
NVY
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
19
PsiBlast_PDB
75.34
29%
-101
- C4 -
1QFE
1
AROD_SALTI
A:
[17-249]
----------------
K
I
I
V
S
L
M
G
R
D
----
I
N
S
V
K
A
-
E
A
L
A
Y
R
E
A
-
T
F
D
I
L
E
W
R
V
D
H
F
MDIA
S
----
T
----
Q
S
V
L
T
A
-
A
R
V
I
R
D
-
A
M
P
D
I
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
T
I
T
T
Q
H
Y
L
T
L
N
R
A
-
A
-
I
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
A
D
V
K
A
T
V
D
Y
A
H
A
H
NVY
V
V
M
S
N
H
D
F
H
Q
T
P
S
A
E
E
M
V
S
R
L
R
K
M
Q
A
L
G
A
D
I
P
K
I
A
V
M
P
Q
S
K
H
D
V
L
T
L
L
T
A
T
L
E
M
Q
Q
H
Y
A
D
R
P
V
I
T
M
S
M
A
K
E
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
Q
A
S
A
P
G
Q
I
A
V
N
D
L
R
S
V
L
M
I
L
H
N
A
8
PsiBlast_PDB
75.30
30%
-95
- C4 -
3M7W
2
AROD_SALTY
A:
[20-252]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
NVA
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
15
PsiBlast_PDB
75.16
30%
-100
- C4 -
4GUH
1
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
13
PsiBlast_PDB
74.95
30%
-106
- C4 -
4GUF
-
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
--------
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
25
PsiBlast_CBE
74.91
35%
-97
- C4 -
3JS3
1
AROD_PEPD6
C:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
KKDI
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
PL
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
KKEVK
V
I
I
S
N
H
D
F
N
K
T
P
KK
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
18
PsiBlast_PDB
74.75
30%
-100
- C4 -
4IUO
1
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
16
PsiBlast_PDB
74.68
30%
-99
- C4 -
3O1N
3
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
NVA
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
A
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
14
PsiBlast_PDB
74.63
30%
-104
- C4 -
4GUG
2
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
A
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
----
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
17
PsiBlast_PDB
74.55
30%
-101
- C4 -
3NNT
1
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
M
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
11
PsiBlast_PDB
74.53
30%
-98
- C4 -
4GUI
2
AROD_SALTY
A:
[20-252]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
12
PsiBlast_PDB
74.52
30%
-97
- C4 -
4GUJ
2
AROD_SALTY
A:
[20-252]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
6
PsiBlast_PDB
74.52
30%
-99
- C4 -
3LB0
2
AROD_SALTY
A:
[41-273]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
-
9
PsiBlast_PDB
74.25
30%
-97
- C4 -
3OEX
1
AROD_SALTY
A:
[20-252]
----------------
K
I
I
V
S
L
M
G
K
T
----
I
T
D
V
K
S
-
E
A
L
A
Y
R
E
A
D
F
-
D
I
L
E
W
R
V
D
H
F
----
A
----
N
VTT
A
E
S
V
L
E
A
-
A
G
A
I
R
E
-
I
I
T
D
K
P
L
--
L
F
T
F
R
S
A
K
E
G
G
E
Q
A
L
T
T
G
Q
Y
I
D
L
N
R
A
-
A
-
V
D
S
G
L
V
D
M
I
D
L
E
L
F
T
G
D
D
E
V
K
A
T
V
G
Y
A
H
Q
H
N
V
A
V
I
M
S
N
H
D
F
H
K
T
P
A
A
E
E
I
V
Q
R
L
R
K
M
Q
E
L
G
A
D
I
P
K
I
A
V
M
P
Q
T
K
A
D
V
L
T
L
L
T
A
T
V
E
M
Q
E
R
Y
A
D
R
P
I
I
T
M
S
M
S
K
T
G
V
I
S
R
L
A
G
E
V
F
G
S
A
A
T
F
G
A
V
K
K
A
S
A
P
G
Q
I
S
V
A
D
L
R
T
V
L
T
I
L
H
Q
A
3
PsiBlast_PDB
74.18
35%
-97
- C4 -
3JS3
1
AROD_PEPD6
A:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
K
K
D
I
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
P
L
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
K
K
E
V
K
V
I
I
S
N
H
D
F
N
K
T
P
K
K
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
24
PsiBlast_CBE
74.17
35%
-93
- C4 -
3JS3
1
AROD_PEPD6
D:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
KKDI
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
PL
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
KKEVK
V
I
I
S
N
H
D
F
N
K
T
P
KK
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
23
PsiBlast_CBE
73.96
35%
-99
- C4 -
4H3D
3
AROD_PEPD6
B:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
K
K
D
I
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
P
L
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
K
K
E
V
K
V
I
I
S
N
H
D
F
N
K
T
P
K
K
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
21
PsiBlast_CBE
73.16
35%
-99
- C4 -
4H3D
3
AROD_PEPD6
D:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
KKDI
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
PL
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
KKEVK
V
I
I
S
N
H
D
F
N
K
T
P
KK
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
--
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
22
PsiBlast_CBE
72.59
35%
-102
- C4 -
4H3D
2
AROD_PEPD6
C:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
KKDI
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
PL
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
KKEVK
V
I
I
S
N
H
D
F
N
K
T
P
KK
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
---
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
26
PsiBlast_CBE
72.46
35%
-98
- C4 -
3JS3
1
AROD_PEPD6
B:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
KKDI
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
PL
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
KKEVK
V
I
I
S
N
H
D
F
N
K
T
P
KK
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
S
V
S
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S
4
PsiBlast_PDB
70.97
35%
-102
- C4 -
4H3D
3
AROD_PEPD6
A:
[21-253]
----------------
K
I
C
V
P
I
I
G
K
N
K
K
D
I
I
K
E
A
K
E
-
L
---
K
D
A
C
-
L
-
D
I
I
E
W
R
V
D
F
F
----
E
----
N
V---
E
N
I
K
E
V
-
K
E
V
L
Y
E
L
R
S
Y
I
H
D
I
P
L
L
F
T
F
R
S
V
V
E
G
G
E
K
L
I
S
R
D
Y
Y
T
T
L
N
K
E
-
I
-
S
N
T
G
L
V
D
L
I
D
V
E
L
F
M
G
D
E
V
I
D
E
V
V
N
F
A
H
K
K
E
V
K
V
I
I
S
N
H
D
F
N
K
T
P
K
K
E
E
I
V
S
R
L
C
R
M
Q
E
L
G
A
D
L
P
K
I
A
V
M
P
Q
N
E
K
D
V
L
V
L
L
E
A
T
N
E
M
F
K
I
Y
A
D
R
P
I
I
T
M
S
M
S
G
M
G
V
I
S
R
L
C
G
E
I
F
G
S
A
L
T
F
G
A
A
K
---
A
P
G
Q
I
S
F
K
E
L
N
S
V
L
N
L
L
H
K
S