@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1501: (2015-12-08 )
MSKKIILGILSLLSVVTLVACGSSDKQLQDKVEKKGKLVLAVSPDYAPFEFKALVNGKDKVVGADIELAQAIADELHVKLEVSPMSFDNVLSSLQTGKADMAISGLSYTKERAKVYDFSKPYYTTENAVLVRKSDLGKYTSIESLKGKKIAVQKGSIEEGVSKKSFKNSHVVSLTAMGEAISELKSGKVEAVDLEKPVAEGYLAQNPDLVLAKFALKTGEGDAKAVALPKDSGKMLKTVNKVIKRLEKEDKYKVYISDAAKLTGNQVE
Atome Classification :
(20 SA)
.........10........20.....-...30........40........50........60........70.....---.---..80....-....90....-....100.......110...--....120.......130.-......140.......150.......160....--.----..170.......180...---....190.......200---.-...--..--.--.210-------.--..-..-..--.220....-----------..-----------------.230........240....----------...250.......260......----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
K
K
I
I
L
G
I
L
S
L
L
S
V
V
T
L
V
ACGSS
D
K
-
Q
L
Q
D
K
V
E
KKG
K
L
V
L
A
VSPDYAP
F
E
F
K
ALVNGKDKVVGA
D
I
E
L
A
Q
A
I
A
DE
L
---
H
---
V
K
L
E
VSPM-
S
F
D
N
V
L
S
S
L
Q-TGKA
D
M
A
ISGLSY
T
K
E
R
AKV--YDFSK
P
Y
Y
TTE
N
A
V
L
V
R
K-SDLGKYT
S
I
E
SLKG
K
K
I
A
V
QKG
S
I
EEGVSKKSF--K----NS
H
V
V
S
L
T
A
M
G
E
A
I
S
E
L
K---SG
K
V
E
A
V
DLEKPVAEG----Y-LAQ--NP--
D
--
L
V
L
--------
A
--
K
F
-
A
L
-KT--GEGD
A
K
A
V
-----------AL-----------------PK-DS
G
K
M
L
K
T
V
N
K
V
I
K
R
L----------EKED
K
Y
K
V
Y
ISD
A
A
K
LTGNQVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
97.58
53%
-75
- C1 -
4H5F
31
?
A:
[8-239]
--------------------------------
I
K
Q
K
G
K
L
V
V
A
T
S
P
D
Y
A
P
F
E
F
Q
S
L
V
D
G
K
N
Q
V
V
G
A
D
I
D
M
A
Q
A
I
A
D
E
L
---
G
---
V
K
L
E
I
L
S
M
-
S
F
D
N
V
L
T
S
L
Q
-
T
G
K
A
D
L
A
V
A
G
I
S
A
T
D
E
R
K
E
V
--
F
D
F
S
I
P
Y
Y
E
N
K
I
S
F
L
V
H
K
-
A
D
V
E
K
Y
K
D
L
T
S
L
E
S
A
N
I
A
A
Q
K
G
T
V
P
E
S
M
V
K
E
Q
L
--
P
----
K
A
Q
L
T
S
L
T
N
M
G
E
A
V
N
E
L
Q
---
A
G
K
I
D
A
V
H
M
D
E
P
V
A
L
S
----
Y
-
A
A
K
--
N
A
--
G
--
L
A
V
--------
A
--
T
V
-
S
L
-
K
M
--
K
D
G
D
A
N
A
V
-----------
A
L
-----------------
R
K
-
N
S
D
D
L
K
E
V
V
D
K
V
I
Q
K
L
----------
K
D
E
G
T
Y
Q
S
Y
L
E
K
A
A
S
L
T
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
96.71
53%
-75
- C1 -
4H5G
10
?
A:
[8-239]
--------------------------------
I
K
Q
K
G
K
L
V
V
A
T
S
P
D
Y
A
P
F
E
F
Q
S
L
V
D
G
K
N
Q
V
V
G
A
D
I
D
M
A
Q
A
I
A
D
E
L
---
G
---
V
K
L
E
I
L
S
M
-
S
F
D
N
V
L
T
S
L
Q
-
T
G
K
A
D
L
A
V
A
G
I
S
A
T
D
E
R
K
E
V
--
F
D
F
S
I
P
Y
Y
E
N
K
I
S
F
L
V
H
K
-
A
D
V
E
K
Y
K
D
L
T
S
L
E
S
A
N
I
A
A
Q
K
G
T
V
P
E
S
M
V
K
E
Q
L
--
P
----
K
A
Q
L
T
S
L
T
N
M
G
E
A
V
N
E
L
Q
---
A
G
K
I
D
A
V
H
M
D
E
P
V
A
L
S
----
Y
-
A
A
K
--
N
A
--
G
--
L
A
V
--------
A
--
T
V
-
S
L
-
K
M
--
K
D
G
D
A
N
A
V
-----------
A
L
-----------------
R
K
-
N
S
D
D
L
K
E
V
V
D
K
V
I
Q
K
L
----------
K
D
E
G
T
Y
Q
S
Y
L
E
K
A
A
S
L
T
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
96.60
53%
-74
- C1 -
4H5G
5
?
B:
[8-239]
--------------------------------
I
K
Q
K
G
K
L
V
V
A
T
S
P
D
Y
A
P
F
E
F
Q
S
L
V
D
G
K
N
Q
V
V
G
A
D
I
D
M
A
Q
A
I
A
D
E
L
---
G
---
V
K
L
E
I
L
S
M
-
S
F
D
N
V
L
T
S
L
Q
-
T
G
K
A
D
L
A
V
A
G
I
S
A
T
D
E
R
K
E
V
--
F
D
F
S
I
P
Y
Y
E
N
K
I
S
F
L
V
H
K
-
A
D
V
E
K
Y
K
D
L
T
S
L
E
S
A
N
I
A
A
Q
K
G
T
V
P
E
S
M
V
K
E
Q
L
--
P
----
K
A
Q
L
T
S
L
T
N
M
G
E
A
V
N
E
L
Q
---
A
G
K
I
D
A
V
H
M
D
E
P
V
A
L
S
----
Y
-
A
A
K
--
N
A
--
G
--
L
A
V
--------
A
--
T
V
-
S
L
-
K
M
--
K
D
G
D
A
N
A
V
-----------
A
L
-----------------
R
K
-
N
S
D
D
L
K
E
V
V
D
K
V
I
Q
K
L
----------
K
D
E
G
T
Y
Q
S
Y
L
E
K
A
A
S
L
T
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
96.28
53%
-74
- C1 -
4H5F
5
?
B:
[8-239]
--------------------------------
I
K
Q
K
G
K
L
V
V
A
T
S
P
D
Y
A
P
F
E
F
Q
S
L
V
D
G
K
N
Q
V
V
G
A
D
I
D
M
A
Q
A
I
A
D
E
L
---
G
---
V
K
L
E
I
L
S
M
-
S
F
D
N
V
L
T
S
L
Q
-
T
G
K
A
D
L
A
V
A
G
I
S
A
T
D
E
R
K
E
V
--
F
D
F
S
I
P
Y
Y
E
N
K
I
S
F
L
V
H
K
-
A
D
V
E
K
Y
K
D
L
T
S
L
E
S
A
N
I
A
A
Q
K
G
T
V
P
E
S
M
V
K
E
Q
L
--
P
----
K
A
Q
L
T
S
L
T
N
M
G
E
A
V
N
E
L
Q
---
A
G
K
I
D
A
V
H
M
D
E
P
V
A
L
S
----
Y
-
A
A
K
--
N
A
--
G
--
L
A
V
--------
A
--
T
V
-
S
L
-
K
M
--
K
D
G
D
A
N
A
V
-----------
A
L
-----------------
R
K
-
N
S
D
D
L
K
E
V
V
D
K
V
I
Q
K
L
----------
K
D
E
G
T
Y
Q
S
Y
L
E
K
A
A
S
L
T
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
96.13
53%
-74
- C1 -
4H5F
16
?
C:
[8-239]
--------------------------------
I
K
Q
K
G
K
L
V
V
A
T
S
P
D
Y
A
P
F
E
F
Q
S
L
V
D
G
K
N
Q
V
V
G
A
D
I
D
M
A
Q
A
I
A
D
E
L
---
G
---
V
K
L
E
I
L
S
M
-
S
F
D
N
V
L
T
S
L
Q
-
T
G
K
A
D
L
A
V
A
G
I
S
A
T
D
E
R
K
E
V
--
F
D
F
S
I
P
Y
Y
E
N
K
I
S
F
L
V
H
K
-
A
D
V
E
K
Y
K
D
L
T
S
L
E
S
A
N
I
A
A
Q
K
G
T
V
P
E
S
M
V
K
E
Q
L
--
P
----
K
A
Q
L
T
S
L
T
N
M
G
E
A
V
N
E
L
Q
---
A
G
K
I
D
A
V
H
M
D
E
P
V
A
L
S
----
Y
-
A
A
K
--
N
A
--
G
--
L
A
V
--------
A
--
T
V
-
S
L
-
K
M
--
K
D
G
D
A
N
A
V
-----------
A
L
-----------------
R
K
-
N
S
D
D
L
K
E
V
V
D
K
V
I
Q
K
L
----------
K
D
E
G
T
Y
Q
S
Y
L
E
K
A
A
S
L
T
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
79.61
48%
-57
- C- -
4I62
3
?
A:
[32-264]
-----------------------------
I
E
A
I
K
S
K
G
K
L
V
V
A
L
N
P
D
F
A
P
F
E
Y
Q
K
V
V
D
G
K
N
Q
I
V
G
S
D
I
E
L
A
K
A
I
A
T
E
L
---
G
---
V
E
L
E
L
S
P
M
-
S
F
D
N
V
L
A
S
V
Q
-
S
G
K
A
D
L
A
I
S
G
V
S
K
T
D
E
R
S
K
V
--
F
D
F
S
T
P
Y
Y
T
A
K
N
K
L
I
V
K
K
-
S
D
L
A
T
Y
Q
S
V
N
D
L
A
Q
K
K
V
G
A
Q
K
G
S
I
Q
E
T
M
A
K
D
L
L
--
Q
----
N
S
S
L
V
S
L
P
K
N
G
N
L
I
T
D
L
K
---
S
G
Q
V
D
A
V
I
F
E
E
P
V
A
K
G
----
F
-
V
E
N
--
N
P
--
D
--
L
A
I
--------
A
--
D
L
-
N
F
-
E
K
---
Q
D
D
S
Y
A
V
-----------
A
M
-----------------
K
K
-
D
S
K
E
L
K
E
A
V
D
K
T
I
Q
K
L
----------
K
E
S
G
E
L
D
K
L
I
E
D
A
F
K
A
S
I
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.47
34%
-68
- C1 -
4PSH
1
?
A:
[3-221]
------------------------------
D
E
I
K
S
R
G
Y
L
L
V
G
L
S
A
D
F
P
P
F
E
F
---
V
D
E
N
G
N
I
V
G
F
D
V
D
L
A
K
E
I
A
R
R
L
---
G
---
V
E
L
K
I
V
D
M
-
T
F
D
G
L
I
P
S
L
L
-
T
K
K
I
D
V
I
I
S
G
M
T
I
T
E
E
R
K
K
V
--
V
A
F
S
D
P
Y
F
D
A
G
Q
V
I
V
V
R
K
-
D
S
D
F
R
P
K
T
Y
E
D
L
V
G
K
T
V
A
V
Q
I
G
T
T
G
D
-
I
E
V
S
K
Y
--
D
----
G
I
K
V
V
R
F
D
K
F
T
D
A
F
L
E
L
K
---
R
G
R
A
D
A
V
V
L
D
S
A
T
A
R
A
----
F
-
V
A
K
--
N
P
--
D
--
L
V
I
--------
S
--
S
G
-
V
L
-
S
S
-----
E
Q
Y
G
I
-----------
A
V
-----------------
R
K
-
E
D
T
D
L
L
E
F
I
N
S
V
L
R
E
L
----------
K
K
S
-
P
Y
D
V
L
I
E
K
W
F
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
79.43
34%
-68
- C1 -
4PSH
1
?
B:
[3-221]
------------------------------
D
E
I
K
S
R
G
Y
L
L
V
G
L
S
A
D
F
P
P
F
E
F
---
V
D
E
N
G
N
I
V
G
F
D
V
D
L
A
K
E
I
A
R
R
L
---
G
---
V
E
L
K
I
V
D
M
-
T
F
D
G
L
I
P
S
L
L
-
T
K
K
I
D
V
I
I
S
G
M
T
I
T
E
E
R
K
K
V
--
V
A
F
S
D
P
Y
F
D
A
G
Q
V
I
V
V
R
K
-
D
S
D
F
R
P
K
T
Y
E
D
L
V
G
K
T
V
A
V
Q
I
G
T
T
G
D
-
I
E
V
S
K
Y
--
D
----
G
I
K
V
V
R
F
D
K
F
T
D
A
F
L
E
L
K
---
R
G
R
A
D
A
V
V
L
D
S
A
T
A
R
A
----
F
-
V
A
K
--
N
P
--
D
--
L
V
I
--------
S
--
S
G
-
V
L
-
S
S
-----
E
Q
Y
G
I
-----------
A
V
-----------------
R
K
-
E
D
T
D
L
L
E
F
I
N
S
V
L
R
E
L
----------
K
K
S
-
P
Y
D
V
L
I
E
K
W
F
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.71
36%
-68
- C1 -
4YMX
1
?
A:
[37-250]
------------------------------------
G
V
I
V
M
G
T
S
A
D
F
P
P
F
E
F
H
K
V
E
G
G
K
D
E
I
V
G
F
D
I
D
I
A
N
A
I
A
K
K
L
---
G
---
V
K
L
E
I
K
D
M
-
D
F
K
G
L
I
P
A
L
Q
-
A
G
R
V
D
M
V
I
A
G
M
T
P
T
A
E
R
K
K
S
--
V
D
F
S
D
L
Y
Y
D
S
R
Q
V
V
V
V
K
N
D
S
P
I
S
K
F
---
D
D
L
K
V
K
T
I
A
V
Q
I
G
T
T
S
E
E
A
A
K
K
-
I
--
P
----
N
V
K
L
K
Q
L
N
R
V
S
D
E
F
M
D
L
Q
---
N
G
R
C
D
A
I
V
V
E
D
T
V
A
K
A
----
Y
-
L
K
E
--
Y
K
--
D
--
M
K
I
--------
L
--
Y
M
-
D
E
-
I
N
--
N
V
E
N
G
S
A
V
-----------
A
V
-----------------
A
K
-
G
N
K
S
L
L
D
V
V
N
E
V
I
K
E
L
----------
K
Q
S
G
E
Y
D
K
L
V
D
K
W
F
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
78.54
36%
-66
- C1 -
4YMX
1
?
B:
[37-250]
------------------------------------
G
V
I
V
M
G
T
S
A
D
F
P
P
F
E
F
H
K
V
E
G
G
K
D
E
I
V
G
F
D
I
D
I
A
N
A
I
A
K
K
L
---
G
---
V
K
L
E
I
K
D
M
-
D
F
K
G
L
I
P
A
L
Q
-
A
G
R
V
D
M
V
I
A
G
M
T
P
T
A
E
R
K
K
S
--
V
D
F
S
D
L
Y
Y
D
S
R
Q
V
V
V
V
K
N
D
S
P
I
S
K
F
---
D
D
L
K
V
K
T
I
A
V
Q
I
G
T
T
S
E
E
A
A
K
K
-
I
--
P
----
N
V
K
L
K
Q
L
N
R
V
S
D
E
F
M
D
L
Q
---
N
G
R
C
D
A
I
V
V
E
D
T
V
A
K
A
----
Y
-
L
K
E
--
Y
K
--
D
--
M
K
I
--------
L
--
Y
M
-
D
E
-
I
N
--
N
V
E
N
G
S
A
V
-----------
A
V
-----------------
A
K
-
G
N
K
S
L
L
D
V
V
N
E
V
I
K
E
L
----------
K
Q
S
G
E
Y
D
K
L
V
D
K
W
F
K
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
77.27
27%
-64
- C1 -
2Y7I
7
?
A:
[3-228]
---------------------------------
V
S
A
R
T
L
H
F
G
T
S
A
T
Y
A
P
Y
E
F
V
D
-
A
--
D
N
K
I
V
G
F
D
I
D
V
A
N
A
V
C
K
E
M
---
Q
---
A
E
C
S
F
T
N
Q
-
S
F
D
S
L
I
P
S
L
R
-
F
K
K
F
D
A
V
I
A
G
M
D
M
T
P
K
R
E
Q
Q
--
V
S
F
S
Q
P
Y
Y
E
G
L
S
A
V
V
V
T
R
-
K
--
G
A
Y
H
T
F
A
D
L
K
G
K
K
V
G
L
E
N
G
T
T
H
Q
R
Y
L
Q
D
K
Q
--
Q
----
A
I
T
P
V
A
Y
D
S
Y
L
N
A
F
T
D
L
K
---
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
K
----
W
-
L
K
N
--
N
P
--
D
--
Y
A
I
--------
M
--
D
E
R
A
S
D
P
D
--
Y
Y
G
K
G
L
G
I
-----------
A
V
-----------------
R
K
-
D
N
D
A
L
L
Q
E
I
N
A
A
L
D
K
V
----------
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
F
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
76.20
24%
-51
- C1 -
2YJP
10
?
A:
[45-280]
--------------------------A
A
T
V
A
A
I
K
E
K
G
V
I
R
I
G
V
F
G
D
K
P
P
F
G
Y
V
D
-
A
--
N
G
K
N
Q
G
F
D
V
E
I
A
K
D
L
A
K
D
L
LGS
P
---
D
K
V
E
F
V
L
T
-
E
A
A
N
R
V
E
Y
V
R
-
S
G
K
V
D
L
I
L
A
N
F
T
Q
T
P
E
R
A
E
A
--
V
D
F
A
D
P
Y
M
K
V
A
L
G
V
V
S
P
K
-
N
K
--
P
I
T
D
M
A
Q
L
K
D
Q
T
L
L
V
N
K
G
T
T
A
D
A
F
F
T
K
S
H
--
P
----
E
V
K
L
L
K
F
D
Q
N
T
E
T
F
D
A
L
K
---
D
G
R
G
V
A
L
A
H
D
N
A
L
L
W
A
----
W
-
A
K
E
--
N
P
--
N
--
F
E
V
--------
A
--
I
G
-
N
L
--
G
---
P
A
E
F
I
A
P
-----------
A
V
-----------------
Q
K
-
G
N
A
D
L
L
N
W
V
N
G
E
I
A
A
M
----------
K
K
D
G
R
L
K
A
A
Y
E
K
T
L
L
P
V
Y
G
E
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
75.25
27%
-72
- C1 -
2Y7I
7
?
A:
[8-219]
--------------------------------------
L
H
F
G
T
S
A
T
Y
A
P
Y
E
F
---
V
D
A
D
N
K
I
V
G
F
D
I
D
V
A
N
A
V
C
K
E
M
---
Q
---
A
E
C
S
F
T
N
Q
-
S
F
D
S
L
I
P
S
L
R
-
F
K
K
F
D
A
V
I
A
G
M
D
M
T
P
K
R
E
Q
Q
--
V
S
F
S
Q
P
Y
Y
E
G
L
S
A
V
V
V
T
R
-
K
--
G
A
Y
H
T
F
A
D
L
K
G
K
K
V
G
L
E
N
G
T
T
H
Q
R
Y
L
Q
D
K
Q
--
Q
----
A
I
T
P
V
A
Y
D
S
Y
L
N
A
F
T
D
L
K
---
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
K
----
W
-
L
K
N
--
N
P
--
D
--
Y
A
I
--------
M
D
E
R
A
-
S
D
-
P
D
--
Y
Y
G
K
G
L
G
I
-----------
A
V
-----------------
R
K
-
D
N
D
A
L
L
Q
E
I
N
A
A
L
D
K
V
----------
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
F
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
74.44
34%
-73
- C1 -
4PRS
-
?
A:
[3-221]
------------------------------
D
E
I
K
S
R
G
Y
L
L
V
G
L
S
A
D
F
P
P
F
E
F
---
V
D
E
N
G
N
I
V
G
F
D
V
D
L
A
K
E
I
A
R
R
L
---
G
---
V
E
L
K
I
V
D
M
-
T
F
D
G
L
I
P
S
L
L
-
T
K
K
I
D
V
I
I
S
G
M
T
I
T
E
E
R
K
K
V
--
V
A
F
S
D
P
Y
F
D
A
G
Q
V
I
V
V
R
K
-
D
S
D
F
R
P
K
T
Y
E
D
L
V
G
K
T
V
A
V
Q
I
G
T
T
G
D
-
I
E
V
S
K
Y
--
D
----
G
I
K
V
V
R
F
D
K
F
T
D
A
F
L
E
L
K
---
R
G
R
A
D
A
V
V
L
D
S
A
T
A
R
A
----
F
-
V
A
K
--
N
P
--
D
--
L
V
I
--------
S
--
S
G
-
V
L
-
S
S
-----
E
Q
Y
G
I
-----------
A
V
-----------------
R
K
-
E
D
T
D
L
L
E
F
I
N
S
V
L
R
E
L
----------
K
K
S
-
P
Y
D
V
L
I
E
K
W
F
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.35
31%
-81
- C1 -
1WDN
1
GLNH_ECOLI
A:
[4-213]
-------------------------------------
K
L
V
V
A
T
D
T
A
F
V
P
F
E
F
K
Q
----
G
D
L
Y
V
G
F
D
V
D
L
W
A
A
I
A
K
E
L
---
K
---
L
D
Y
E
L
K
P
M
-
D
F
S
G
I
I
P
A
L
Q
-
T
K
N
V
D
L
A
L
A
G
I
T
I
T
D
E
R
K
K
A
--
I
D
F
S
D
G
Y
Y
K
S
G
L
L
V
M
V
-
K
-
A
N
N
N
D
V
K
S
V
K
D
L
D
G
K
V
V
A
V
K
S
G
T
G
S
V
D
Y
A
K
A
N
I
--
K
----
T
K
D
L
R
Q
F
P
N
I
D
N
A
Y
M
E
L
G
---
T
N
R
A
D
A
V
---------------
L
H
D
--
T
P
--
N
--
I
L
Y
------------
F
-
I
K
-
T
A
--
G
N
G
Q
F
K
A
V
G
DSLEA
Q
Q
Y
G
I
A
F
-----------------
P
K
-
G
S
D
E
L
R
D
K
V
N
G
A
L
K
T
L
----------
R
E
N
G
T
Y
N
E
I
Y
K
K
W
F
G
T
E
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
73.35
28%
-62
- C1 -
2PVU
3
?
A:
[38-265]
--------------------------------
G
A
T
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
----
K
G
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
---
G
---
L
D
Y
E
L
K
N
I
-
G
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
T
D
E
R
K
Q
S
--
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
-
G
S
--
P
V
K
N
A
L
D
L
K
G
K
T
I
G
V
Q
N
A
T
T
G
Q
E
A
A
E
K
L
F
--
G
K---
G
P
H
I
K
K
F
E
T
T
V
V
A
I
M
E
L
L
---
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
E
----
Y
-
V
K
N
--
N
P
--
N
KK
L
Q
V
--------
I
--
E
D
-
P
K
-
N
F
---
A
S
E
Y
Y
G
M
-----------
I
F
-----------------
P
K
--
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
----------
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
Fugue
72.91
27%
-64
- C1 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
------------------------
A
P
-
T
A
L
E
R
V
Q
K
E
G
V
L
R
V
I
T
R
N
S
P
A
T
Y
-----
F
Q
D
R
N
G
E
T
G
F
E
Y
E
L
A
K
R
F
A
E
R
L
---
G
---
V
E
L
K
I
E
T
A
D
N
L
D
D
L
Y
A
Q
L
S
R
E
G
G
P
A
L
A
A
A
G
L
T
P
G
R
E
D
D
A
S
--
V
R
Y
S
H
T
Y
L
D
V
-
T
P
Q
I
I
Y
R
-
N
G
Q
Q
R
P
T
R
P
E
D
L
V
G
K
R
I
M
V
L
K
G
S
------------------
S
H
A
E
Q
L
A
E
L
K
K
Q
Y
P
E
L
K
Y
E
E
S
D
A
V
E
V
V
D
L
L
R
M
V
D
V
G
DID
L
T
-
L
V
D
--
S
N
--
E
--
L
A
M
N
QVYFPN-
V
--
R
V
-
A
F
-
D
F
--
G
E
A
R
G
L
A
W
-----------
A
L
-----------------
P
G
G
D
D
D
S
L
M
N
E
V
N
A
F
L
D
Q
A
----------
K
K
E
G
L
L
Q
R
L
K
D
R
Y
Y
----
G
H
V
D
VLG
Y
V
G
A
Y
T
F
A
Q
H
L
Q
Q
RLPRY
E
S
H
F
K
Q
S
G
K
Q
L
DTD
W
R
L
L
A
A
I
G
Y
Q
E
SLWQPGATSKTGVRGLMMLT
N
R
T
A
Q
A
M
GVSNRLD
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
LPESIKE
P
D
R
S
W
F
A
L
A
A
Y
N
IG
G
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
K
K
M
LPRLAQKQWYAKTRYGYAR
G
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
63
Fugue
72.68
25%
-41
- C1 -
4Z9N
5
?
A:
[9-328]
-------------------------
A
-
D
T
L
S
D
V
K
A
K
G
F
L
Q
C
G
V
N
T
G
L
L
G
F
---
A
S
P
N
D
K
G
E
W
S
G
F
D
V
D
Y
C
R
A
V
A
S
A
I
---
F
GDP
T
K
V
K
F
T
P
L
-
N
A
K
E
R
F
T
A
L
Q
-
S
G
E
V
D
V
L
I
R
N
T
T
W
T
I
S
R
D
T
S
LG
L
D
F
A
G
I
N
Y
Y
D
G
Q
G
F
M
I
N
S
-
K
K
L
A
G
I
N
S
A
L
Q
L
S
G
A
S
I
C
V
Q
A
G
T
T
T
E
L
N
M
A
D
Y
F
--
R
A
N
K
M
E
Y
N
P
V
V
F
E
K
I
E
E
A
N
A
A
Y
D
---
S
G
R
C
D
A
Y
T
T
D
Q
S
S
L
Y
G
----
V
-
R
L
A
LA
N
P
--
D
--
D
H
V
I
L
PEII
S
K
E
--
P
F
-
G
L
-
T
V
--
R
Q
G
D
A
R
W
A
-----------
D
V
V
R
W
T
H
N
A
L
L
N
A
E
E
Y
GIT
Q
A
-
N
V
E
E
M
K
K
S
D
N
P
D
I
K
R
L
L
GAEADTK
I
G
T
D
L
G
L
D
K
D
W
V
V
K
I
I
K
G
V
G
N
Y
G
E
I
F
E
R
N
IGSGSPLKIARGLNAQWNKGGL
Q
Y
G
I
P
VR------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
72.14
26%
-52
- C1 -
1LST
1
ARGT_SALTY
A:
[2-234]
----------------------------------
L
P
Q
T
V
R
I
G
T
D
T
T
Y
A
P
F
S
S
K
D
-
A
--
K
G
E
F
I
G
F
D
I
D
L
G
N
E
M
C
K
R
M
---
Q
---
V
K
C
T
W
V
A
S
-
D
F
D
A
L
I
P
S
L
K
-
A
K
K
I
D
A
I
I
S
S
L
S
I
T
D
K
R
Q
Q
E
--
I
A
F
S
D
K
L
Y
A
A
D
S
R
L
I
A
A
K
-
G
S
-
P
I
Q
P
T
L
E
S
L
K
G
K
H
V
G
V
L
Q
G
S
T
Q
E
A
Y
A
N
D
N
W
RT
K
----
G
V
D
V
V
A
Y
A
N
Q
D
L
I
Y
S
D
L
T
---
A
G
R
L
D
A
A
L
Q
D
E
V
A
A
S
E
----
G
F
L
K
Q
--
P
A
GK
E
--
Y
A
F
--------
A
--
G
P
-
S
V
-
K
D
KK
Y
F
G
D
G
T
G
V
-----------
G
L
-----------------
R
K
-
D
D
T
E
L
K
A
A
F
D
K
A
L
T
E
L
----------
R
Q
D
G
T
Y
D
K
M
A
K
K
Y
F
D
F
N
V
Y
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
72.03
24%
-53
- C1 -
1XT8
1
?
A:
[34-264]
-------------------------
L
-
N
S
L
D
K
I
K
Q
N
G
V
V
R
I
G
V
F
G
D
K
P
P
F
G
Y
V
D
-
E
--
K
G
N
N
Q
G
Y
D
I
A
L
A
K
R
I
A
K
E
L
---
F
GDE
N
K
V
Q
F
V
L
V
-
E
A
A
N
R
V
E
F
L
K
-
S
N
K
V
D
I
I
L
A
N
F
T
Q
T
P
Q
R
A
E
Q
--
V
D
F
C
S
P
Y
M
K
V
A
L
G
V
A
V
P
K
-
D
S
--
N
I
T
S
V
E
D
L
K
D
K
T
L
L
L
N
K
G
T
T
A
D
A
Y
F
T
Q
N
Y
--
P
----
N
I
K
T
L
K
Y
D
Q
N
T
E
T
F
A
A
L
M
---
D
K
R
G
D
A
L
S
H
D
N
T
L
L
F
A
----
W
-
V
K
D
--
H
P
--
D
--
F
K
M
--------
G
--
I
K
-
E
L
--
G
---
N
K
D
V
I
A
P
-----------
A
V
-----------------
K
K
-
G
D
K
E
L
K
E
F
I
D
N
L
I
I
K
L
----------
G
Q
E
Q
F
F
H
K
A
Y
D
E
T
L
K
A
H
F
G
D
D
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------