@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1560: (2015-12-08 )
MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALQGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......-..10........20........30........40........50...-......60.-----.-.-..-..--.-----70.----.......80........90........100......-.110-........120....-...-130..---.....-.---140.-......150.......160.......170.......180........190.......200.......210.......-220-.......230.......240.......250.......260.......270.......280.......290.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFKS
G
F
-
V
A
I
LGRPNV
G
K
S
T
F
L
N
H
VMG
Q
K
I
A
I
MSDKAQTTRN
K
I
M
G
I
Y
TT-ET
E
-
Q
I
V
F
IDTPG-----I-H-K
P
-
K
T
--
A
-----
L
G
D
----
F
M
V
E
S
A
Y
S
T
L
R
E
V
E
T
V
L
F
M
VPADEKRGKG
D
D
M
I
I
E
R
-
L
K
A--AKI
P
V
I
L
V
I
NKIDKV-
H
P
D
-
Q
-
L
L
E
---
Q
I
D
D
F
-
R
---SQM
D
-
F
K
EVVPISALQGNN
V
P
T
L
I
K
L
L
T
D
N
L
E
E
G
F
QYFPEDQI-TD
H
P
E
R
F
L
V
S
E
M
V
R
E
K
V
L
H
L
T
Q
Q
EVP
H
S
V
A
V
V
V
E
S
M
KR-DEE-T
D
K
V
H
I
R
A
T
I
M
V
ERDSQK
G
I
I
IGKQ
G
A
M
L
K
K
I
G
K
M
A
R
R
D
I
E
L
MLG
D
K
V
Y
L
E
T
W
V
K
V
K
KNWRDKKLDLADFGYNEKEY
67
HHSearch
96.10
47%
-106
- C1 -
3IEV
4
ERA_AQUAE
A:
[7-307]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
N
E
A
-
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
K
SD
V
-----
L
G
H
----
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
---
L
I
D
E
I
-
H
---
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
-
G
D
A
N
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
---
3
PsiBlast_PDB
95.59
46%
-108
- C1 -
3IEV
4
ERA_AQUAE
A:
[8-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
-
P
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
K
--
S
D
V
---
L
G
H
----
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
---
L
I
D
E
I
H
K
---
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
-
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
---
2
PsiBlast_PDB
94.07
46%
-108
- C1 -
3R9X
4
ERA_AQUAE
A:
[7-305]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
-
P
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
K
--
S
D
V
---
L
G
H
----
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
---
L
I
D
E
I
H
K
---
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
-
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
---
1
PsiBlast_PDB
93.70
46%
-111
- C1 -
3R9W
8
ERA_AQUAE
A:
[7-305]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
G
Y
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
-
P
N
E
A
Q
I
I
F
L
D
T
P
G
-----
I
-
Y
-
E
P
-
K
K
--
S
D
V
---
L
G
H
----
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
-
G
P
A
-
K
N
V
L
P
---
L
I
D
E
I
H
K
---
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
N
-
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
---
6
PsiBlast_PDB
91.20
43%
-115
- C1 -
3IEU
7
ERA_ECOLI
A:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
R
--
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
-
R
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
-
A
D
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
R
-
G
G
-
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
22
PsiBlast_CBE
90.78
43%
-116
- C1 -
1EGA
2
ERA_ECOLI
B:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
R
--
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
-
R
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
-
A
D
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
R
-
G
G
-
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
21
PsiBlast_CBE
90.65
43%
-114
- C1 -
3IEU
9
ERA_ECOLI
B:
[8-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
R
--
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
-
R
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
-
A
D
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
R
-
G
G
-
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
------
4
PsiBlast_PDB
89.37
43%
-111
- C1 -
1EGA
3
ERA_ECOLI
A:
[8-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
M
E
E
-
K
R
--
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
-
R
W
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
-
A
D
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
R
-
G
G
-
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
65
HHSearch
88.71
43%
-108
- C1 -
1EGA
3
ERA_ECOLI
A:
[5-295]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
Y
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
-
H
-
M
E
-
E
K
R
-
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
-
Q
E
K
A
D
-
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
--
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-------
8
PsiBlast_PDB
86.65
38%
-96
- C1 -
1WF3
4
ERA_THET8
A:
[7-297]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
F
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
E
-
G
R
R
-
Q
I
V
F
V
D
T
P
G
-----
L
-
H
-
K
P
-
M
D
--
A
-----
L
G
E
----
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
A
-
L
K
P
LV
G
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
Y
P
E
-
E
-
A
M
K
---
A
Y
H
E
L
-
L
---
P
E
A
E
-
P
R
M
---
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
--
E
R
E
-
N
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
---
66
HHSearch
86.39
39%
-90
- C1 -
1WF3
4
ERA_THET8
A:
[4-298]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
Y
S
G
F
-
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
E
-
G
R
R
-
Q
I
V
F
V
D
T
P
G
-----
L
-
H
-
K
P
-
M
D
--
A
-----
L
G
E
----
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
P
T
P
E
D
E
L
V
A
R
A
-
L
K
P
LV
G
K
V
P
I
L
L
V
G
N
K
L
D
A
A
-
K
Y
P
-
E
---
E
---
A
M
K
A
Y
-
H
---
E
L
L
P
-
E
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
-
R
E
--
N
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
---
55
Fugue
67.75
44%
-111
- C1 -
1EGA
3
ERA_ECOLI
A:
[4-182]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
S
Y
C
G
F
-
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
-
G
A
Y
-
Q
A
I
Y
V
D
T
P
G
-----
L
H
M
-
E
E
-
K
R
--
A
-----
I
N
R
----
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
T
R
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
E
K
A
-
D
-
L
L
P
---
H
L
Q
F
L
-
A
---
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-
N
E
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
--------
17
PsiBlast_PDB
67.37
28%
-128
- C1 -
3PR1
1
ENGB_THEMA
A:
[24-193]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
-
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
-------------
R
S
--
I
N
F
Y
L
V
-
N
S
--
K
Y
Y
F
V
D
L
P
G
Y---------
K
-
E
R
--
M
-----
L
W
K
----
R
L
V
E
D
Y
F
K
N
R
W
S
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
W
-
M
K
S
--
L
N
I
P
F
T
I
V
L
T
K
M
D
K
V
-
K
M
S
-
E
-
R
A
K
---
K
L
E
E
H
-
R
K
V
F
S
K
Y
G
-
E
Y
T
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
66.48
28%
-119
- C1 -
3PQC
2
ENGB_THEMA
A:
[24-193]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
-
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
--
I
N
F
Y
L
V
-
N
S
--
K
Y
Y
F
V
D
L
P
G
YGYAK
V
-
S
-
K
K
-
E
R
--
M
-----
L
W
K
----
R
L
V
E
D
Y
F
K
N
R
W
S
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
W
-
M
K
S
--
L
N
I
P
F
T
I
V
L
T
K
M
D
K
V
-
K
M
S
-
E
-
R
A
K
---
K
L
E
E
H
-
R
K
V
F
S
K
Y
G
-
E
Y
T
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
65.32
31%
-131
- C1 -
4KYU
5
DER_BACSU
B:
[6-163]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
-----------------
I
Y
S
S
A
E
W
--
N
Y
-
D
F
N
L
I
D
T
G
G
-----
I
-
D
-
I
G
-
D
E
--
P
-----
F
L
A
----
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
K
K
P
V
V
L
A
V
N
K
L
D
N
T
-----
E
-
M
R
A
---
N
I
Y
D
F
-
Y
---
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
-------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
64.00
28%
-103
- C1 -
3PQC
2
ENGB_THEMA
A:
[21-193]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
K
G
E
-
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
I
N
---
F
Y
L
-
V
N
S
-
K
Y
Y
F
V
D
L
P
G
-----
Y
-
G
-
Y
A
-
K
V
--
S
K
K
E
R
M
L
W
K
----
R
L
V
E
D
Y
F
K
N
R
W
S
L
Q
M
V
F
L
L
V
D
G
R
I
P
P
Q
D
S
D
L
M
M
V
E
W
-
M
K
S
--
L
N
I
P
F
T
I
V
L
T
K
M
D
K
V
-
K
M
S
-
E
-
R
A
K
K
L
E
E
H
R
K
V
-
F
---
S
K
Y
G
-
E
Y
T
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
62.44
31%
-113
- C1 -
4KYU
6
DER_BACSU
A:
[6-163]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
----------
R
D
R
I
Y
S
S
A
E
W
-
L
N
Y
-
D
F
N
L
I
D
T
G
G
-----
I
-
D
-
I
G
-
D
E
--
P
-----
F
L
A
----
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
K
K
P
V
V
L
A
V
N
K
L
D
N
T
-----
E
-
M
R
A
---
N
I
Y
D
F
-
Y
---
S
-
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
-------------------------------------------------------------------------------------------------------------------------------------
86
HHSearch
61.57
27%
-104
- C1 -
2DYK
1
?
A:
[2-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
-
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
E
T
-
D
R
G
-
R
F
L
L
V
D
T
G
G
-----
L
-
W
-
S
G
-
D
K
--
W
------
E
K
----
K
I
Q
E
K
V
D
R
A
L
E
D
A
E
V
V
L
F
A
V
D
G
R
A
E
L
T
Q
A
D
Y
E
V
A
E
Y
-
L
R
R
--
K
G
K
P
V
I
L
V
A
T
K
V
D
D
P
-
K
H
E
-
L
-
Y
L
G
---
P
L
--------
Y
G
L
G
-
F
G
D
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
P
------------------------------------------------------------------------------------------------------------------------------------
57
Fugue
61.07
24%
-82
- C1 -
1XZP
3
MNME_THEMA
A:
[27-482]
SSVDKL
M
D
T
I
V
A
VATPPGKGA
I
A
I
L
R
L
S
GPD
S
W
K
I
V
Q
K
H
L
R
T
R
SKIVPRKA
I
H
G
W
I
H
ENGED
V
D
E
V
V
V
V
F
Y
K
SPKSYTG
E
D
M
V
E
V
M
C
HGG
P
L
V
V
K
K
L
L
D
L
F
L
K
S
GARMAEPG
E
F
T
K
R
A
F
L
N
GKMD
L
T
S
A
E
A
V
R
D
L
I
E
AKS
E
T
S
L
K
L
S
L
R
N
L
K
G
G
L
R
D
F
V
D
S
L
R
R
E
L
I
E
V
L
A
E
I
R
V
E
L
D
Y
PDEIETN
T
G
E
V
V
T
R
L
E
R
I
K
E
K
L
T
E
E
L
K
K
A
D
A
G
I
L
L
N
R
G
L
R
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
D
R
A
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
I
-
R
G
I
-
L
F
R
I
V
D
T
A
G
-----
V
-
R
-
S
E
T
N
D
--
L
-----
V
E
R
----
L
G
I
E
R
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
S
S
P
L
D
E
E
D
R
K
I
L
E
R
-
I
K
N
--
K
--
R
Y
L
V
V
I
N
K
V
D
V
V
-
E
K
I
-
N
-
E
E
E
---
I
K
N
K
L
-
G
---
T
D
----
R
H
M
V
K
I
S
A
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
Q
E
I
F
E
R
G
S
D
S
L
I
-
T
N
---------------------------------------
L
-
R
Q
K
Q
L
L
E
N
V
K
G
H
L
E
D
A
I
K
S
L
K
E
G
M
P
V
D
M
A
S
I
D
L
E
R
A
L
N
L
L
D
E
V
T
G
R
S
F
R
E
D
L
L
D
T
I
F
S
N
F
C
V
G
K
-------------
18
PsiBlast_PDB
60.90
27%
-109
- C1 -
2DYK
1
?
A:
[4-160]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
E
T
-
D
R
G
-
R
F
L
L
V
D
T
G
G
-----
L
-
W
-
S
-------------
G
D
KWE
K
K
I
Q
E
K
V
D
R
A
L
E
D
A
E
V
V
L
F
A
V
D
G
R
A
E
L
T
Q
A
D
Y
E
V
A
E
Y
-
L
R
R
--
K
G
K
P
V
I
L
V
A
T
K
V
D
D
P
-
K
H
E
-
L
-
Y
L
G
---
P
L
--------
Y
G
L
G
-
F
G
D
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
P
------------------------------------------------------------------------------------------------------------------------------------