@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1626: (2015-12-09 )
MKKGLMISFEGPDGAGKTTVLEAVLPLLREKLSQDILTTREPGGVTISEEIRHIILDVKHTQMDKKTELLLYMAARRQHLVEKVLPALEEGKIVLMDRFIDSSVAYQGSGRGLDKSHIKWLNDYATDSHKPDLTLYFDVPSEVGLERIQKSVQREVNRLDLEQLDMHQRVRQGYLELADSEPNRIVTIDASQQLDEVIAETFSIILDRINQ
Atome Classification :
(50 SA)
.........10........20........30----......-..40........50........60.---........70........80....-....90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......---200.......210-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKK
G
L
M
I
S
F
EGPDGAG
K
T
T
V
L
E
A
V
L
P
L
L
R
E
K
----
L
S
Q
D
I
L-TTREPG
G
V
T
I
S
E
E
I
R
H
I
I
L
DVKH-T---QMD
K
K
T
E
L
L
L
Y
M
A
A
R
R
Q
H
L
V
E
K
V
L
-
P
A
L
EEG
K
I
V
L
M
DRFIDSS
V
A
YQGSGRGL
D
K
S
H
I
K
W
L
N
D
YATDSHKP
D
L
T
L
Y
F
DV
P
S
E
V
G
L
E
R
I
Q
K
S
V
Q
R
E
V
N
RL
D
L
E
Q
L
D
M
H
Q
R
V
R
Q
G
Y
L
E
LADSEP
N
R
I
V
T
ID
A
S
Q
Q
L
D
E
V
I
A
---
E
T
F
S
I
I
L
D
RINQ--
8
PsiBlast_PDB
87.55
47%
-87
- C1 -
4HEJ
1
KTHY_STAAN
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-----
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
---
29
PsiBlast_CBE
86.86
47%
-88
- C1 -
4QGH
2
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
-------
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
21
PsiBlast_CBE
86.81
47%
-88
- C1 -
4EAQ
1
KTHY_STAAM
B:
[28-223]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
35
PsiBlast_CBE
86.75
47%
-85
- C1 -
4HDC
1
KTHY_STAAN
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
30
PsiBlast_CBE
86.71
47%
-86
- C1 -
4QGG
1
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
34
PsiBlast_CBE
86.63
47%
-85
- C1 -
4HLC
1
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
31
PsiBlast_CBE
86.54
47%
-82
- C1 -
4QGA
1
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
32
PsiBlast_CBE
86.49
47%
-83
- C1 -
4QG7
1
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
16
PsiBlast_PDB
86.35
47%
-83
- C1 -
4XWA
1
KTHY_STAA1
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
----
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
4
PsiBlast_PDB
86.35
47%
-88
- C1 -
2CCJ
5
KTHY_STAAM
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
---
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
----
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
14
PsiBlast_PDB
86.25
47%
-83
- C1 -
4QGG
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
------------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
37
PsiBlast_CBE
86.19
40%
-83
- C1 -
4GMD
4
KTHY_PSEAE
D:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
--------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
GLD
R
L
L
P
N
L
L
E
R
L
N
---
9
PsiBlast_PDB
85.90
47%
-85
- C1 -
4HLC
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
--------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
---
6
PsiBlast_PDB
85.87
47%
-88
- C1 -
4GSY
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
10
PsiBlast_PDB
85.85
47%
-83
- C1 -
4HLD
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
28
PsiBlast_CBE
85.79
47%
-90
- C1 -
4XWA
2
KTHY_STAA1
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
11
PsiBlast_PDB
85.70
47%
-81
- C1 -
4QG7
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
33
PsiBlast_CBE
85.64
47%
-84
- C1 -
4HLD
1
KTHY_STAAR
B:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
2
PsiBlast_PDB
85.59
47%
-85
- C1 -
4EAQ
1
KTHY_STAAM
A:
[28-223]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
---------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
18
PsiBlast_PDB
85.57
47%
-86
- C1 -
4MQB
2
KTHY_STAAM
A:
[7-202]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
--
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
5
PsiBlast_PDB
85.46
47%
-89
- C1 -
4GFD
1
KTHY_STAAM
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
15
PsiBlast_PDB
85.44
47%
-82
- C1 -
4QGH
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
--
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
7
PsiBlast_PDB
85.35
47%
-84
- C1 -
4HDC
1
KTHY_STAAN
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
13
PsiBlast_PDB
85.31
47%
-82
- C1 -
4QGF
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
---------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
41
PsiBlast_CBE
85.27
40%
-73
- C1 -
4EDH
4
KTHY_PSEAE
B:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
----
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
G
--
19
PsiBlast_PDB
85.10
40%
-75
- C1 -
4EDH
5
KTHY_PSEAE
A:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
A
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
---
12
PsiBlast_PDB
85.03
47%
-83
- C1 -
4QGA
1
KTHY_STAAR
A:
[4-199]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
38
PsiBlast_CBE
84.88
40%
-81
- C1 -
4GMD
3
KTHY_PSEAE
C:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-------------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
---
36
PsiBlast_CBE
84.76
47%
-80
- C1 -
2CCG
1
KTHY_STAAM
B:
[24-219]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
-----
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
17
PsiBlast_PDB
83.92
47%
-82
- C1 -
2CCG
1
KTHY_STAAM
A:
[24-219]
-----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
E
V
Y
H
R
L
V
K
D
----
Y
--
D
V
I
-
M
T
R
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
--
G
-
N
---
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
-
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
N
A
D
Q
P
L
E
N
V
V
E
---
D
T
Y
Q
T
I
I
K
Y
L
E
K
--
39
PsiBlast_CBE
83.72
40%
-80
- C1 -
4GMD
4
KTHY_PSEAE
B:
[6-211]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
--------------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
----
20
PsiBlast_PDB
83.47
40%
-78
- C1 -
4ESH
1
KTHY_PSEAE
A:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
------
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
---
46
PsiBlast_CBE
83.24
40%
-79
- C1 -
3UWO
1
KTHY_PSEAE
B:
[11-213]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
--------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
-------
47
PsiBlast_CBE
82.80
40%
-79
- C1 -
3UWO
1
KTHY_PSEAE
A:
[11-215]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-------------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
-----
48
PsiBlast_CBE
81.93
40%
-81
- C1 -
3UWK
1
KTHY_PSEAE
B:
[23-228]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
------------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
----
40
PsiBlast_CBE
81.30
40%
-74
- C1 -
4GMD
3
KTHY_PSEAE
A:
[6-212]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
-------
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
---
43
PsiBlast_CBE
81.23
40%
-79
- C1 -
3UXM
3
KTHY_PSEAE
C:
[2-207]
---
G
L
F
V
T
L
E
G
P
E
G
A
---
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
A
----
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
----
44
PsiBlast_CBE
81.20
40%
-70
- C1 -
3UXM
1
KTHY_PSEAE
B:
[2-206]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
A
A
R
G
--
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
-----
45
PsiBlast_CBE
80.22
40%
-83
- C1 -
3UXM
3
KTHY_PSEAE
A:
[2-207]
---
G
L
F
V
T
L
E
G
P
E
G
----
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
-------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
----
42
PsiBlast_CBE
80.16
40%
-71
- C1 -
3UXM
1
KTHY_PSEAE
D:
[2-204]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
A
A
R
G
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
-------
59
PsiBlast_CBE
79.52
39%
-77
- C1 -
3N2I
2
KTHY_VIBCH
B:
[29-232]
-----
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
N
----
G
I
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
-
E
H
-
P
G
E
-
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
-
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
A
R
G
--
R
G
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
D
-
D
S
V
V
M
I
D
A
A
Q
S
I
E
Q
V
T
A
---
D
I
R
R
A
L
Q
D
W
L
S
Q
--
49
PsiBlast_CBE
78.81
40%
-70
- C1 -
3UWK
2
KTHY_PSEAE
A:
[23-227]
---
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
Y
L
A
E
R
L
R
E
R
-----
G
I
E
V
Q
-
L
T
R
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
S
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
-
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
--
A
A
A
R
---
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
D
A
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
-----
60
PsiBlast_CBE
78.22
39%
-80
- C1 -
3N2I
2
KTHY_VIBCH
A:
[29-232]
-----
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
N
----
G
I
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
-
E
H
-
P
GE-
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
-
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
A
R
G
----
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
D
-
D
S
V
V
M
I
D
A
A
Q
S
I
E
Q
V
T
A
---
D
I
R
R
A
L
Q
D
W
L
S
Q
--
61
PsiBlast_CBE
78.04
39%
-79
- C1 -
3LV8
8
KTHY_VIBCH
A:
[29-232]
-----
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
N
----
G
I
D
H
I
T
-
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
-
E
H
-
P
GE-
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
-
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-------
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
D
-
D
S
V
V
M
I
D
A
A
Q
S
I
E
Q
V
T
A
---
D
I
R
R
A
L
Q
D
W
L
S
Q
--
81
Fugue
76.48
38%
-73
- C1 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
--
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
V
V
V
E
T
L
E
Q
L
----
G
I
R
D
M
V
-
F
T
R
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
D
I
K
S
-
V
GD
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
-
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
--
G
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
D
-
K
S
I
H
T
I
D
A
T
-
Q
P
L
E
A
V
M
---
D
A
I
R
T
T
V
T
H
W
V
K
E
L
95
HHSearch
75.70
36%
-72
- C1 -
3LV8
8
KTHY_VIBCH
A:
[26-231]
--
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
V
V
V
E
T
L
Q
Q
N
----
G
-
I
D
H
I
T
R
T
R
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
E
H
P
G
E
---
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
-
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-----
E
L
D
--
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
-
D
D
S
V
V
M
I
D
A
A
Q
S
I
E
Q
V
T
A
---
D
I
R
R
A
L
Q
D
W
L
S
Q
--
92
HHSearch
75.39
37%
-72
- C1 -
3V9P
5
KTHY_BURTA
A:
[23-226]
-
A
R
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
R
L
G
P
A
G
-
R
H
V
V
-
V
T
R
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
N
Q
-------
P
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
-
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
V
R
M
P
-----
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
D
S
S
E
P
I
A
Q
I
R
K
---
Q
L
E
G
V
L
A
A
L
-----
101
HHSearch
74.54
41%
-75
* C1 *
3HJN
3
KTHY_THEMA
A:
[1-192]
----
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
E
K
R
----
G
-
K
K
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
E
-------
E
V
T
P
K
A
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
-
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
K
---
N
R
F
E
-------
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
K
R
S
I
E
E
I
H
R
---
D
V
V
R
E
V
K
R
R
-----
53
PsiBlast_CBE
71.47
43%
-67
- C1 -
3HJN
3
KTHY_THEMA
A:
[1-181]
----
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
-
E
K
----
R
G
K
K
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
----
E
---
E
V
T
P
K
A
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
-
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
-----
K
---
N
R
--
F
E
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
K
R
S
I
E
E
I
H
R
---
D
V
V
R
E
V
K
R
R
-----
52
PsiBlast_CBE
69.27
43%
-69
- C1 -
3HJN
2
KTHY_THEMA
B:
[1-181]
----
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
L
L
A
Q
Y
L
-
E
K
----
R
G
K
K
V
I
-
L
K
R
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
----
E
---
E
V
T
P
K
A
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
-
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
---------
N
R
--
F
E
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
D
G
K
R
S
I
E
E
I
H
R
---
D
V
V
R
E
---------